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The Subcutaneous Adipose Microenvironment as a Determinant of Body Fat Development in Polycystic Ovary Syndrome. J Endocr Soc. 2024 Sep 26; 8(11):bvae162.
Dumesic DA, Rasouli MA, Katz JD, Lu GG, Dharanipragada D, Turcu AF, Grogan TR, Flores KE, Magyar CE, Abbott DH, Chazenbalk GD. PMID: 39345868; PMCID: PMC11424691.
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PubMed Mentions:
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Anti-Müllerian Hormone: A Molecular Key to Unlocking Polycystic Ovary Syndrome? Semin Reprod Med. 2024 Mar; 42(1):41-48.
Abbott DH, Hutcherson BA, Dumesic DA. PMID: 38908381.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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An Evolutionary Model for the Ancient Origins of Polycystic Ovary Syndrome. J Clin Med. 2023 Sep 22; 12(19).
Dumesic DA, Abbott DH, Chazenbalk GD. PMID: 37834765; PMCID: PMC10573644.
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PubMed Mentions:
2
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Interplay of Cortisol, Testosterone, and Abdominal Fat Mass in Normal-weight Women With Polycystic Ovary Syndrome. J Endocr Soc. 2023 Jul 03; 7(8):bvad079.
Dumesic DA, Turcu AF, Liu H, Grogan TR, Abbott DH, Lu G, Dharanipragada D, Chazenbalk GD. PMID: 37404244; PMCID: PMC10315644.
View in:
PubMed Mentions:
4
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Randomized clinical trial: effect of low-dose flutamide on abdominal adipogenic function in normal-weight women with polycystic ovary syndrome. Fertil Steril. 2023 01; 119(1):116-126.
Dumesic DA, Winnett C, Lu G, Grogan TR, Abbott DH, Naik R, Chazenbalk GD. PMID: 36400597.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Experimentally Induced Hyperinsulinemia Fails to Induce Polycystic Ovary Syndrome-like Traits in Female Rhesus Macaques. Int J Mol Sci. 2022 Feb 27; 23(5).
Zhou R, Bruns CM, Bird IM, Kemnitz JW, Dumesic DA, Abbott DH. PMID: 35269778; PMCID: PMC8910161.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Female Adult Acne and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee. J Endocr Soc. 2022 Mar 01; 6(3):bvac003.
Carmina E, Dreno B, Lucky WA, Agak WG, Dokras A, Kim JJ, Lobo RA, Ramezani Tehrani F, Dumesic D. PMID: 35155970; PMCID: PMC8826298.
View in:
PubMed Mentions:
15
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Polycystic ovary syndrome as a plausible evolutionary outcome of metabolic adaptation. Reprod Biol Endocrinol. 2022 Jan 10; 20(1):12.
Dumesic DA, Padmanabhan V, Chazenbalk GD, Abbott DH. PMID: 35012577; PMCID: PMC8744313.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
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Serum Testosterone to Androstenedione Ratio Predicts Metabolic Health in Normal-Weight Polycystic Ovary Syndrome Women. J Endocr Soc. 2021 Nov 01; 5(11):bvab158.
Dumesic DA, Tulberg A, McNamara M, Grogan TR, Abbott DH, Naik R, Lu G, Chazenbalk GD. PMID: 34661039; PMCID: PMC8513761.
View in:
PubMed Mentions:
7
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Passing on PCOS: new insights into its epigenetic transmission. Cell Metab. 2021 03 02; 33(3):463-466.
Abbott DH, Dumesic DA. PMID: 33657389; PMCID: PMC9133658.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Accelerated subcutaneous abdominal stem cell adipogenesis predicts insulin sensitivity in normal-weight women with polycystic ovary syndrome. Fertil Steril. 2021 07; 116(1):232-242.
Dumesic DA, Tulberg A, Leung KL, Fisch SC, Grogan TR, Abbott DH, Naik R, Chazenbalk GD. PMID: 33341231; PMCID: PMC8209112.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Dynamic changes in chromatin accessibility, altered adipogenic gene expression, and total versus de novo fatty acid synthesis in subcutaneous adipose stem cells of normal-weight polycystic ovary syndrome (PCOS) women during adipogenesis: evidence of cellular programming. Clin Epigenetics. 2020 11 23; 12(1):181.
Leung KL, Sanchita S, Pham CT, Davis BA, Okhovat M, Ding X, Dumesic P, Grogan TR, Williams KJ, Morselli M, Ma F, Carbone L, Li X, Pellegrini M, Dumesic DA, Chazenbalk GD. PMID: 33228780; PMCID: PMC7686698.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Loss of anti-Müllerian hormone (AMH) immunoactivity due to a homozygous AMH gene variant rs10417628 in a woman with classical polycystic ovary syndrome (PCOS). Hum Reprod. 2020 10 01; 35(10):2294-2302.
Hoyos LR, Visser JA, McLuskey A, Chazenbalk GD, Grogan TR, Dumesic DA. PMID: 32918081; PMCID: PMC7518710.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Midgestation origins of androgenic and estrogenic pathophysiology in three major women's health disorders. Fertil Steril. 2020 12; 114(6):1183-1184.
Abbott DH, Dumesic DA. PMID: 32919706; PMCID: PMC8131034.
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PubMed Mentions: Fields:
Translation:
Humans
-
Intergenerational programming and in vitro fertilization: another turn of the screw. Fertil Steril. 2020 12; 114(6):1167-1168.
Hoyos LR, Dumesic DA. PMID: 32873372.
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PubMed Mentions: Fields:
Translation:
Humans
-
Androgen Receptors in Multiple Organ Systems Provide Molecular Gateways to Polycystic Ovary Syndrome. Endocrinology. 2020 08 01; 161(8).
Abbott DH, Levine JE, Dumesic DA. PMID: 32530028; PMCID: PMC7446857.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Developmental Programming: Sheep Granulosa and Theca Cell-Specific Transcriptional Regulation by Prenatal Testosterone. Endocrinology. 2020 08 01; 161(8).
Puttabyatappa M, Guo X, Dou J, Dumesic D, Bakulski KM, Padmanabhan V. PMID: 32516392; PMCID: PMC7417881.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Animal Models to Understand the Etiology and Pathophysiology of Polycystic Ovary Syndrome. Endocr Rev. 2020 07 01; 41(4).
Stener-Victorin E, Padmanabhan V, Walters KA, Campbell RE, Benrick A, Giacobini P, Dumesic DA, Abbott DH. PMID: 32310267; PMCID: PMC7279705.
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PubMed Mentions:
113 Fields:
Translation:
HumansAnimals
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Measures of Patient Dissatisfaction With Health Care in Polycystic Ovary Syndrome: Retrospective Analysis. J Med Internet Res. 2020 04 21; 22(4):e16541.
Hoyos LR, Putra M, Armstrong AA, Cheng CY, Riestenberg CK, Schooler TA, Dumesic DA. PMID: 32314967; PMCID: PMC7201322.
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PubMed Mentions:
16 Fields:
Translation:
Humans
-
Endocrine-Metabolic Dysfunction in Polycystic Ovary Syndrome: an Evolutionary Perspective. Curr Opin Endocr Metab Res. 2020 Jun; 12:41-48.
Dumesic DA, Abbott DH, Sanchita S, Chazenbalk GD. PMID: 32363240; PMCID: PMC7194185.
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PubMed Mentions:
23
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A primate perspective on oocytes and transgenerational PCOS. Reprod Biomed Online. 2020 06; 40(6):765-767.
Dumesic DA, Wood JR, Abbott DH, Strauss JF. PMID: 32312513; PMCID: PMC7847722.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Mechanisms of intergenerational transmission of polycystic ovary syndrome. Reproduction. 2020 01; 159(1):R1-R13.
Dumesic DA, Hoyos LR, Chazenbalk GD, Naik R, Padmanabhan V, Abbott DH. PMID: 31376813; PMCID: PMC6989388.
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PubMed Mentions:
34 Fields:
Translation:
HumansPHPublic Health
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Naturally Occurring and Experimentally Induced Rhesus Macaque Models for Polycystic Ovary Syndrome: Translational Gateways to Clinical Application. Med Sci (Basel). 2019 Nov 27; 7(12).
Abbott DH, Rogers J, Dumesic DA, Levine JE. PMID: 31783681; PMCID: PMC6950671.
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PubMed Mentions:
15 Fields:
-
In utero Androgen Excess: A Developmental Commonality Preceding Polycystic Ovary Syndrome? Front Horm Res. 2019; 53:1-17.
Abbott DH, Kraynak M, Dumesic DA, Levine JE. PMID: 31499494; PMCID: PMC6954824.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
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Massive Ovarian Growth in a Woman With Severe Insulin-Resistant Polycystic Ovary Syndrome Receiving GnRH Analogue. J Clin Endocrinol Metab. 2019 07 01; 104(7):2796-2800.
Singh P, Agress A, Madrigal VK, Magyar C, Ostrzega N, Chazenbalk GD, Dumesic DA. PMID: 30759233; PMCID: PMC6894611.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Adipose Insulin Resistance in Normal-Weight Women With Polycystic Ovary Syndrome. J Clin Endocrinol Metab. 2019 06 01; 104(6):2171-2183.
Dumesic DA, Phan JD, Leung KL, Grogan TR, Ding X, Li X, Hoyos LR, Abbott DH, Chazenbalk GD. PMID: 30649347; PMCID: PMC6482023.
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PubMed Mentions:
36 Fields:
Translation:
Humans
-
Polycystic Ovary Syndrome: Impact of Lipotoxicity on Metabolic and Reproductive Health. Obstet Gynecol Surv. 2019 Apr; 74(4):223-231.
Brennan KM, Kroener LL, Chazenbalk GD, Dumesic DA. PMID: 31344250; PMCID: PMC6952118.
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PubMed Mentions:
14 Fields:
Translation:
Humans
-
Hyperandrogenic origins of polycystic ovary syndrome - implications for pathophysiology and therapy. Expert Rev Endocrinol Metab. 2019 03; 14(2):131-143.
Abbott DH, Dumesic DA, Levine JE. PMID: 30767580; PMCID: PMC6992448.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimals
-
Precocious subcutaneous abdominal stem cell development to adipocytes in normal-weight women with polycystic ovary syndrome. Fertil Steril. 2018 12; 110(7):1367-1376.
Fisch SC, Nikou AF, Wright EA, Phan JD, Leung KL, Grogan TR, Abbott DH, Chazenbalk GD, Dumesic DA. PMID: 30503136; PMCID: PMC6287278.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Reproductive and metabolic determinants of granulosa cell dysfunction in normal-weight women with polycystic ovary syndrome. Fertil Steril. 2018 03; 109(3):508-515.
Guedikian AA, Lee AY, Grogan TR, Abbott DH, Largaespada K, Chazenbalk GD, Dumesic DA. PMID: 29428312; PMCID: PMC5812340.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Developmental Programming: Impact of Prenatal Testosterone Excess on Steroidal Machinery and Cell Differentiation Markers in Visceral Adipocytes of Female Sheep. Reprod Sci. 2018 07; 25(7):1010-1023.
Puttabyatappa M, Lu C, Martin JD, Chazenbalk G, Dumesic D, Padmanabhan V. PMID: 29237348; PMCID: PMC6346350.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Pluripotent nontumorigenic multilineage differentiating stress enduring cells (Muse cells): a seven-year retrospective. Stem Cell Res Ther. 2017 10 18; 8(1):227.
Fisch SC, Gimeno ML, Phan JD, Simerman AA, Dumesic DA, Perone MJ, Chazenbalk GD. PMID: 29041955; PMCID: PMC5646122.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Use of fertility medications and cancer risk: a review and update. Curr Opin Obstet Gynecol. 2017 Aug; 29(4):195-201.
Kroener L, Dumesic D, Al-Safi Z. PMID: 28538003; PMCID: PMC5551049.
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PubMed Mentions:
14 Fields:
Translation:
Humans
-
Cost-Benefit Analysis of Hysteroscopic Polypectomy Before Controlled Ovarian Hyperstimulation and Intrauterine Insemination in Infertile Women. J Reprod Med. 2017 Mar-Apr; 62(3-4):127-32.
Sundheimer LW, Kathiresan A, Dumesic D, Parvataneni R, Shamonki M. PMID: 30230303.
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PubMed Mentions: Fields:
Translation:
Humans
-
Attributes That Fellowship Directors Value in the Selection of Reproductive Endocrinology and Infertility Fellows. J Reprod Med. 2017 Jan-Feb; 62(1-2):31-6.
Kaing A, Kathiresan ASQ, Dumesic D, Shamonki M. PMID: 29999279.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Muse Cells: Nontumorigenic Pluripotent Stem Cells Present in Adult Tissues-A Paradigm Shift in Tissue Regeneration and Evolution. Stem Cells Int. 2016; 2016:1463258.
Simerman AA, Phan JD, Dumesic DA, Chazenbalk GD. PMID: 28070194; PMCID: PMC5192335.
View in:
PubMed Mentions:
10
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Hyperandrogenism Accompanies Increased Intra-Abdominal Fat Storage in Normal Weight Polycystic Ovary Syndrome Women. J Clin Endocrinol Metab. 2016 11; 101(11):4178-4188.
Dumesic DA, Akopians AL, Madrigal VK, Ramirez E, Margolis DJ, Sarma MK, Thomas AM, Grogan TR, Haykal R, Schooler TA, Okeya BL, Abbott DH, Chazenbalk GD. PMID: 27571186; PMCID: PMC5095243.
View in:
PubMed Mentions:
81 Fields:
Translation:
HumansCells
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Cumulus Cell Mitochondrial Resistance to Stress In Vitro Predicts Oocyte Development During Assisted Reproduction. J Clin Endocrinol Metab. 2016 05; 101(5):2235-45.
Dumesic DA, Guedikian AA, Madrigal VK, Phan JD, Hill DL, Alvarez JP, Chazenbalk GD. PMID: 27003307.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Translational Insight Into Polycystic Ovary Syndrome (PCOS) From Female Monkeys with PCOS-like Traits. Curr Pharm Des. 2016; 22(36):5625-5633.
Abbott DH, Levine JE, Dumesic DA. PMID: 27426126; PMCID: PMC5673087.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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Developmental Programming: Impact of Gestational Steroid and Metabolic Milieus on Adiposity and Insulin Sensitivity in Prenatal Testosterone-Treated Female Sheep. Endocrinology. 2016 Feb; 157(2):522-35.
Cardoso RC, Veiga-Lopez A, Moeller J, Beckett E, Pease A, Keller E, Madrigal V, Chazenbalk G, Dumesic D, Padmanabhan V. PMID: 26650569; PMCID: PMC4733129.
View in:
PubMed Mentions:
35 Fields:
Translation:
Animals
-
Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome. Endocr Rev. 2015 Oct; 36(5):487-525.
Dumesic DA, Oberfield SE, Stener-Victorin E, Marshall JC, Laven JS, Legro RS. PMID: 26426951; PMCID: PMC4591526.
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PubMed Mentions:
340 Fields:
Translation:
Humans
-
Phospholipase C-zeta deficiency as a cause for repetitive oocyte fertilization failure during ovarian stimulation for in vitro fertilization with ICSI: a case report. J Assist Reprod Genet. 2015 Sep; 32(9):1415-9.
Chithiwala ZH, Lee HC, Hill DL, Jellerette-Nolan T, Fissore R, Grow D, Dumesic DA. PMID: 26174123; PMCID: PMC4595401.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Inflammatory Factors in Reproductive Medicine. Semin Reprod Med. 2015 Jul; 33(4):237.
Dumesic D. PMID: 26132927.
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PubMed Mentions: Fields:
Translation:
Humans
-
Disparities and relative risk ratio of preterm birth in six Central and Eastern European centers. Croat Med J. 2015 Apr; 56(2):119-27.
Arora CP, Kacerovsky M, Zinner B, Ertl T, Ceausu I, Rusnak I, Shurpyak S, Sandhu M, Hobel CJ, Dumesic DA, Vari SG. PMID: 25891871; PMCID: PMC4410174.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Oocyte environment: follicular fluid and cumulus cells are critical for oocyte health. Fertil Steril. 2015 Feb; 103(2):303-16.
Dumesic DA, Meldrum DR, Katz-Jaffe MG, Krisher RL, Schoolcraft WB. PMID: 25497448.
View in:
PubMed Mentions:
236 Fields:
Translation:
HumansAnimalsCells
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Exploring the potential association between brominated diphenyl ethers, polychlorinated biphenyls, organochlorine pesticides, perfluorinated compounds, phthalates, and bisphenol A in polycystic ovary syndrome: a case-control study. BMC Endocr Disord. 2014 Oct 28; 14:86.
Vagi SJ, Azziz-Baumgartner E, Sjödin A, Calafat AM, Dumesic D, Gonzalez L, Kato K, Silva MJ, Ye X, Azziz R. PMID: 25348326; PMCID: PMC4287339.
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PubMed Mentions:
47 Fields:
Translation:
HumansPHPublic Health
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Intrafollicular cortisol levels inversely correlate with cumulus cell lipid content as a possible energy source during oocyte meiotic resumption in women undergoing ovarian stimulation for in vitro fertilization. Fertil Steril. 2015 Jan; 103(1):249-57.
Simerman AA, Hill DL, Grogan TR, Elashoff D, Clarke NJ, Goldstein EH, Manrriquez AN, Chazenbalk GD, Dumesic DA. PMID: 25439840; PMCID: PMC4380141.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCellsCTClinical Trials
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Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys. PLoS One. 2014; 9(9):e106527.
Nicol LE, O'Brien TD, Dumesic DA, Grogan T, Tarantal AF, Abbott DH. PMID: 25207967; PMCID: PMC4160158.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansAnimals
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Pluripotent muse cells derived from human adipose tissue: a new perspective on regenerative medicine and cell therapy. Clin Transl Med. 2014; 3:12.
Simerman AA, Dumesic DA, Chazenbalk GD. PMID: 24940477; PMCID: PMC4041046.
View in:
PubMed Mentions:
19 Fields:
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Protein phospholipase C Zeta1 expression in patients with failed ICSI but with normal sperm parameters. J Assist Reprod Genet. 2014 Jun; 31(6):749-56.
Lee HC, Arny M, Grow D, Dumesic D, Fissore RA, Jellerette-Nolan T. PMID: 24756570; PMCID: PMC4048377.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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A mystery unraveled: nontumorigenic pluripotent stem cells in human adult tissues. Expert Opin Biol Ther. 2014 Jul; 14(7):917-29.
Simerman AA, Perone MJ, Gimeno ML, Dumesic DA, Chazenbalk GD. PMID: 24745973; PMCID: PMC4100978.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Impaired preadipocyte differentiation into adipocytes in subcutaneous abdominal adipose of PCOS-like female rhesus monkeys. Endocrinology. 2014 Jul; 155(7):2696-703.
Keller E, Chazenbalk GD, Aguilera P, Madrigal V, Grogan T, Elashoff D, Dumesic DA, Abbott DH. PMID: 24735327; PMCID: PMC4060192.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Intrauterine environment and polycystic ovary syndrome. Semin Reprod Med. 2014 May; 32(3):159-65.
Dumesic DA, Goodarzi MO, Chazenbalk GD, Abbott DH. PMID: 24715510; PMCID: PMC4800983.
View in:
PubMed Mentions:
38 Fields:
Translation:
Humans
-
21-Hydroxylase-derived steroids in follicles of nonobese women undergoing ovarian stimulation for in vitro fertilization (IVF) positively correlate with lipid content of luteinized granulosa cells (LGCs) as a source of cholesterol for steroid synthesis. J Clin Endocrinol Metab. 2014 Apr; 99(4):1299-306.
Amin M, Simerman A, Cho M, Singh P, Briton-Jones C, Hill D, Grogan T, Elashoff D, Clarke NJ, Chazenbalk GD, Dumesic DA. PMID: 24423334; PMCID: PMC3973780.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Pluripotent stem cells derived from mouse and human white mature adipocytes. Stem Cells Transl Med. 2014 Feb; 3(2):161-71.
Jumabay M, Abdmaulen R, Ly A, Cubberly MR, Shahmirian LJ, Heydarkhan-Hagvall S, Dumesic DA, Yao Y, Boström KI. PMID: 24396033; PMCID: PMC3925054.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Awakened by cellular stress: isolation and characterization of a novel population of pluripotent stem cells derived from human adipose tissue. PLoS One. 2013; 8(6):e64752.
Heneidi S, Simerman AA, Keller E, Singh P, Li X, Dumesic DA, Chazenbalk G. PMID: 23755141; PMCID: PMC3673968.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansCells
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Androgens inhibit adipogenesis during human adipose stem cell commitment to preadipocyte formation. Steroids. 2013 Sep; 78(9):920-6.
Chazenbalk G, Singh P, Irge D, Shah A, Abbott DH, Dumesic DA. PMID: 23707571; PMCID: PMC3951890.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansCells
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Introduction to the special issue: 2012 AE-PCOS meeting. Steroids. 2013 Aug; 78(8):733.
Carmina E, Dumesic D. PMID: 23643846.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimals
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Cancer risk and PCOS. Steroids. 2013 Aug; 78(8):782-5.
Dumesic DA, Lobo RA. PMID: 23624028.
View in:
PubMed Mentions:
80 Fields:
Translation:
Humans
-
A novel approach to quantifying ovarian cell lipid content and lipid accumulation in vitro by confocal microscopy in lean women undergoing ovarian stimulation for in vitro fertilization (IVF). J Assist Reprod Genet. 2013 Jun; 30(5):733-40.
Singh P, Amin M, Keller E, Simerman A, Aguilera P, Briton-Jones C, Hill DL, Abbott DH, Chazenbalk G, Dumesic DA. PMID: 23512091; PMCID: PMC3663971.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Ontogeny of the ovary in polycystic ovary syndrome. Fertil Steril. 2013 Jul; 100(1):23-38.
Dumesic DA, Richards JS. PMID: 23472949; PMCID: PMC4562327.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Phenotypic expression of polycystic ovary syndrome in South Asian women. Obstet Gynecol Surv. 2013 Mar; 68(3):228-34.
Mehta J, Kamdar V, Dumesic D. PMID: 23945839.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
Effects of endogenous androgens and abdominal fat distribution on the interrelationship between insulin and non-insulin-mediated glucose uptake in females. J Clin Endocrinol Metab. 2013 Apr; 98(4):1541-8.
Ezeh U, Pall M, Mathur R, Dey D, Berman D, Chen IY, Dumesic DA, Azziz R. PMID: 23450052; PMCID: PMC3615210.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Nonhuman primate models of polycystic ovary syndrome. Mol Cell Endocrinol. 2013 Jul 05; 373(1-2):21-8.
Abbott DH, Nicol LE, Levine JE, Xu N, Goodarzi MO, Dumesic DA. PMID: 23370180; PMCID: PMC3683573.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimals
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Early-to-mid gestation fetal testosterone increases right hand 2D:4D finger length ratio in polycystic ovary syndrome-like monkeys. PLoS One. 2012; 7(8):e42372.
Abbott AD, Colman RJ, Tiefenthaler R, Dumesic DA, Abbott DH. PMID: 22927929; PMCID: PMC3425513.
View in:
PubMed Mentions:
34 Fields:
Translation:
Animals
-
The effect of timing of embryonic progression on chromosomal abnormality. Fertil Steril. 2012 Oct; 98(4):876-80.
Kroener L, Ambartsumyan G, Briton-Jones C, Dumesic D, Surrey M, Munné S, Hill D. PMID: 22789142.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Androgen disorders. Steroids. 2012 Mar 10; 77(4):289.
Carmina E, Dumesic D. PMID: 22178786.
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PubMed Mentions: Fields:
Translation:
Humans
-
Consensus on women's health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group. Fertil Steril. 2012 Jan; 97(1):28-38.e25.
Fauser BC, Tarlatzis BC, Rebar RW, Legro RS, Balen AH, Lobo R, Carmina E, Chang J, Yildiz BO, Laven JS, Boivin J, Petraglia F, Wijeyeratne CN, Norman RJ, Dunaif A, Franks S, Wild RA, Dumesic D, Barnhart K. PMID: 22153789.
View in:
PubMed Mentions:
507 Fields:
Translation:
Humans
-
Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys. PLoS One. 2011; 6(11):e27286.
Xu N, Kwon S, Abbott DH, Geller DH, Dumesic DA, Azziz R, Guo X, Goodarzi MO. PMID: 22076147; PMCID: PMC3208630.
View in:
PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Novel pathway of adipogenesis through cross-talk between adipose tissue macrophages, adipose stem cells and adipocytes: evidence of cell plasticity. PLoS One. 2011 Mar 31; 6(3):e17834.
Chazenbalk G, Bertolotto C, Heneidi S, Jumabay M, Trivax B, Aronowitz J, Yoshimura K, Simmons CF, Dumesic DA, Azziz R. PMID: 21483855; PMCID: PMC3069035.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCells
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Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol. 2011 Apr; 7(4):219-31.
Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R. PMID: 21263450.
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462 Fields:
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Humans
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Polycystic ovary syndrome: an ancient disorder? Fertil Steril. 2011 Apr; 95(5):1544-8.
Azziz R, Dumesic DA, Goodarzi MO. PMID: 20979996; PMCID: PMC3164771.
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48 Fields:
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Humans
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Experimentally induced gestational androgen excess disrupts glucoregulation in rhesus monkey dams and their female offspring. Am J Physiol Endocrinol Metab. 2010 Nov; 299(5):E741-51.
Abbott DH, Bruns CR, Barnett DK, Dunaif A, Goodfriend TL, Dumesic DA, Tarantal AF. PMID: 20682841; PMCID: PMC2980359.
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51 Fields:
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Animals
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Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome (AE-PCOS) Society. J Clin Endocrinol Metab. 2010 May; 95(5):2038-49.
Wild RA, Carmina E, Diamanti-Kandarakis E, Dokras A, Escobar-Morreale HF, Futterweit W, Lobo R, Norman RJ, Talbott E, Dumesic DA. PMID: 20375205.
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283 Fields:
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Humans
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Fetal, infant, adolescent and adult phenotypes of polycystic ovary syndrome in prenatally androgenized female rhesus monkeys. Am J Primatol. 2009 Sep; 71(9):776-84.
Abbott DH, Tarantal AF, Dumesic DA. PMID: 19367587; PMCID: PMC2916860.
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66 Fields:
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Animals
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Intrafollicular antimüllerian hormone levels predict follicle responsiveness to follicle-stimulating hormone (FSH) in normoandrogenic ovulatory women undergoing gonadotropin releasing-hormone analog/recombinant human FSH therapy for in vitro fertilization and embryo transfer. Fertil Steril. 2009 Jul; 92(1):217-21.
Dumesic DA, Lesnick TG, Stassart JP, Ball GD, Wong A, Abbott DH. PMID: 18675414; PMCID: PMC2703699.
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18 Fields:
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Humans
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Menstrual cycle and surgical treatment of breast cancer: findings from the NCCTG N9431 study. J Clin Oncol. 2009 Aug 01; 27(22):3620-6.
Grant CS, Ingle JN, Suman VJ, Dumesic DA, Wickerham DL, Gelber RD, Flynn PJ, Weir LM, Intra M, Jones WO, Perez EA, Hartmann LC. PMID: 19487378; PMCID: PMC2799061.
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11 Fields:
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HumansCTClinical Trials
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Developmental programming: excess weight gain amplifies the effects of prenatal testosterone excess on reproductive cyclicity--implication for polycystic ovary syndrome. Endocrinology. 2009 Mar; 150(3):1456-65.
Steckler TL, Herkimer C, Dumesic DA, Padmanabhan V. PMID: 18974266; PMCID: PMC2654744.
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40 Fields:
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Animals
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Endocrine antecedents of polycystic ovary syndrome in fetal and infant prenatally androgenized female rhesus monkeys. Biol Reprod. 2008 Jul; 79(1):154-63.
Abbott DH, Barnett DK, Levine JE, Padmanabhan V, Dumesic DA, Jacoris S, Tarantal AF. PMID: 18385445; PMCID: PMC2531213.
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PubMed Mentions:
57 Fields:
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Animals
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Plasma free fatty acid storage in subcutaneous and visceral adipose tissue in postabsorptive women. Diabetes. 2008 May; 57(5):1186-94.
Koutsari C, Dumesic DA, Patterson BW, Votruba SB, Jensen MD. PMID: 18285557.
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29 Fields:
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HumansCells
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Fetal programming of adrenal androgen excess: lessons from a nonhuman primate model of polycystic ovary syndrome. Endocr Dev. 2008; 13:145-158.
Abbott DH, Zhou R, Bird IM, Dumesic DA, Conley AJ. PMID: 18493139; PMCID: PMC2531212.
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31 Fields:
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HumansAnimals
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Implications of polycystic ovary syndrome on oocyte development. Semin Reprod Med. 2008 Jan; 26(1):53-61.
Dumesic DA, Abbott DH. PMID: 18181083; PMCID: PMC2655636.
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43 Fields:
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HumansCells
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Polycystic ovary syndrome and oocyte developmental competence. Obstet Gynecol Surv. 2008 Jan; 63(1):39-48.
Dumesic DA, Padmanabhan V, Abbott DH. PMID: 18081939; PMCID: PMC2655633.
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43 Fields:
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HumansCells
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Meal fatty acid uptake in visceral fat in women. Diabetes. 2007 Oct; 56(10):2589-97.
Votruba SB, Mattison RS, Dumesic DA, Koutsari C, Jensen MD. PMID: 17664244.
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32 Fields:
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Humans
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Polycystic ovary syndrome and its developmental origins. Rev Endocr Metab Disord. 2007 Jun; 8(2):127-41.
Dumesic DA, Abbott DH, Padmanabhan V. PMID: 17659447; PMCID: PMC2935197.
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PubMed Mentions:
113 Fields:
Translation:
HumansAnimals
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Omental 11beta-hydroxysteroid dehydrogenase 1 correlates with fat cell size independently of obesity. Obesity (Silver Spring). 2007 May; 15(5):1155-63.
Michailidou Z, Jensen MD, Dumesic DA, Chapman KE, Seckl JR, Walker BR, Morton NM. PMID: 17495191.
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PubMed Mentions:
32 Fields:
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Humans
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Increased adiposity enhances intrafollicular estradiol levels in normoandrogenic ovulatory women receiving gonadotropin-releasing hormone analog/recombinant human follicle-stimulating hormone therapy for in vitro fertilization. J Clin Endocrinol Metab. 2007 Apr; 92(4):1438-41.
Dumesic DA, Lesnick TG, Abbott DH. PMID: 17244784.
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PubMed Mentions:
4 Fields:
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Humans
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Pioglitazone improves insulin action and normalizes menstrual cycles in a majority of prenatally androgenized female rhesus monkeys. Reprod Toxicol. 2007 Apr-May; 23(3):438-48.
Zhou R, Bruns CM, Bird IM, Kemnitz JW, Goodfriend TL, Dumesic DA, Abbott DH. PMID: 17306503; PMCID: PMC2705750.
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PubMed Mentions:
30 Fields:
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Animals
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Molecular abnormalities in oocytes from women with polycystic ovary syndrome revealed by microarray analysis. J Clin Endocrinol Metab. 2007 Feb; 92(2):705-13.
Wood JR, Dumesic DA, Abbott DH, Strauss JF. PMID: 17148555.
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105 Fields:
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HumansCells
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Contributions of androgen and estrogen to fetal programming of ovarian dysfunction. Reprod Biol Endocrinol. 2006 Apr 10; 4:17.
Abbott DH, Padmanabhan V, Dumesic DA. PMID: 16606451; PMCID: PMC1459165.
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27 Fields:
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HumansAnimals
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Follicle luteinization in hyperandrogenic follicles of polycystic ovary syndrome patients undergoing gonadotropin therapy for in vitro fertilization. J Clin Endocrinol Metab. 2006 Jun; 91(6):2327-33.
Foong SC, Abbott DH, Zschunke MA, Lesnick TG, Phy JL, Dumesic DA. PMID: 16551732.
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PubMed Mentions:
24 Fields:
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Humans
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Diagnosis of polycystic ovaries by three-dimensional transvaginal ultrasound. Fertil Steril. 2006 Jan; 85(1):214-9.
Allemand MC, Tummon IS, Phy JL, Foong SC, Dumesic DA, Session DR. PMID: 16412756.
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23 Fields:
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Humans
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Adrenal hyperandrogenism is induced by fetal androgen excess in a rhesus monkey model of polycystic ovary syndrome. J Clin Endocrinol Metab. 2005 Dec; 90(12):6630-7.
Zhou R, Bird IM, Dumesic DA, Abbott DH. PMID: 16174719; PMCID: PMC1350929.
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PubMed Mentions:
28 Fields:
Translation:
Animals
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Diminished intrafollicular estradiol levels in in vitro fertilization cycles from women with reduced ovarian response to recombinant human follicle-stimulating hormone. Fertil Steril. 2005 May; 83(5):1377-83.
Foong SC, Abbott DH, Lesnick TG, Session DR, Walker DL, Dumesic DA. PMID: 15866572.
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PubMed Mentions:
7 Fields:
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Humans
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Early origins of polycystic ovary syndrome. Reprod Fertil Dev. 2005; 17(3):349-60.
Dumesic DA, Schramm RD, Abbott DH. PMID: 15745643.
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PubMed Mentions:
30 Fields:
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AnimalsCells
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Insulin and messenger ribonucleic acid expression of insulin receptor isoforms in ovarian follicles from nonhirsute ovulatory women and polycystic ovary syndrome patients. J Clin Endocrinol Metab. 2004 Jul; 89(7):3561-6.
Phy JL, Conover CA, Abbott DH, Zschunke MA, Walker DL, Session DR, Tummon IS, Thornhill AR, Lesnick TG, Dumesic DA. PMID: 15240646.
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PubMed Mentions:
18 Fields:
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HumansCells
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Vitrification versus programmable rate freezing of late stage murine embryos: a randomized comparison prior to application in clinical IVF. Reprod Biomed Online. 2004 May; 8(5):558-68.
Walker DL, Tummon IS, Hammitt DG, Session DR, Dumesic DA, Thornhill AR. PMID: 15151720.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Cumulative first live birth after elective cryopreservation of all embryos due to ovarian hyperresponsiveness. Fertil Steril. 2004 Feb; 81(2):309-14.
Tummon IS, Contag SA, Thornhill AR, Session DR, Dumesic DA, Damario MA. PMID: 14967365.
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HumansCells
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Nonhuman primates contribute unique understanding to anovulatory infertility in women. ILAR J. 2004; 45(2):116-31.
Abbott DH, Foong SC, Barnett DK, Dumesic DA. PMID: 15111731.
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7 Fields:
Translation:
HumansAnimals
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Regional uptake of meal fatty acids in humans. Am J Physiol Endocrinol Metab. 2003 Dec; 285(6):E1282-8.
Jensen MD, Sarr MG, Dumesic DA, Southorn PA, Levine JA. PMID: 12915396.
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PubMed Mentions:
42 Fields:
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HumansCTClinical Trials
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Reduced intrafollicular androstenedione and estradiol levels in early-treated prenatally androgenized female rhesus monkeys receiving follicle-stimulating hormone therapy for in vitro fertilization. Biol Reprod. 2003 Oct; 69(4):1213-9.
Dumesic DA, Schramm RD, Bird IM, Peterson E, Paprocki AM, Zhou R, Abbott DH. PMID: 12801996.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Prevalence and predictors of coronary artery calcification in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2003 Jun; 88(6):2562-8.
Christian RC, Dumesic DA, Behrenbeck T, Oberg AL, Sheedy PF, Fitzpatrick LA. PMID: 12788855.
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PubMed Mentions:
90 Fields:
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Humans
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Ultrasound-guided unification of noncommunicating uterine cavities. JSLS. 2003 Apr-Jun; 7(2):155-7.
Mullesserill BT, Dumesic DA, Damario MA, Session DR. PMID: 12856848; PMCID: PMC3015487.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Increased adiposity in female rhesus monkeys exposed to androgen excess during early gestation. Obes Res. 2003 Feb; 11(2):279-86.
Eisner JR, Dumesic DA, Kemnitz JW, Colman RJ, Abbott DH. PMID: 12582225.
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PubMed Mentions:
55 Fields:
Translation:
Animals
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Impaired developmental competence of oocytes in adult prenatally androgenized female rhesus monkeys undergoing gonadotropin stimulation for in vitro fertilization. J Clin Endocrinol Metab. 2002 Mar; 87(3):1111-9.
Dumesic DA, Schramm RD, Peterson E, Paprocki AM, Zhou R, Abbott DH. PMID: 11889174.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Ovarian hyperandrogenism in adult female rhesus monkeys exposed to prenatal androgen excess. Fertil Steril. 2002 Jan; 77(1):167-72.
Eisner JR, Barnett MA, Dumesic DA, Abbott DH. PMID: 11779609.
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PubMed Mentions:
44 Fields:
Translation:
Animals