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Particle Radiation Side-Effects: Intestinal Microbiota Composition Shapes Interferon-γ-Induced Osteo-Immunogenicity. Radiat Res. 2022 Feb 01; 197(2):184-192.
Maier I, Ruegger PM, Deutschmann J, Helbich TH, Pietschmann P, Schiestl RH, Borneman J. PMID: 35130347.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Cyanovirin-N Binds Viral Envelope Proteins at the Low-Affinity Carbohydrate Binding Site without Direct Virus Neutralization Ability. Molecules. 2021 Jun 13; 26(12).
Maier I, Schiestl RH, Kontaxis G. PMID: 34199200; PMCID: PMC8231982.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Intestinal bacterial indicator phylotypes associate with impaired DNA double-stranded break sensors but augmented skeletal bone micro-structure. Carcinogenesis. 2020 06 17; 41(4):483-489.
Maier I, Liu J, Ruegger PM, Deutschmann J, Patsch JM, Helbich TH, Borneman J, Schiestl RH. PMID: 31840161; PMCID: PMC7456343.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Mannosylated hemagglutinin peptides bind cyanovirin-N independent of disulfide-bonds in complementary binding sites. RSC Adv. 2020 Mar 16; 10(19):11079-11087.
Schilling PE, Kontaxis G, Dragosits M, Schiestl RH, Becker CFW, Maier I. PMID: 35495330; PMCID: PMC9050506.
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PubMed Mentions:
3
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A novel probiotic, Lactobacillus johnsonii 456, resists acid and can persist in the human gut beyond the initial ingestion period. Gut Microbes. 2019; 10(4):458-480.
Davoren MJ, Liu J, Castellanos J, Rodríguez-Malavé NI, Schiestl RH. PMID: 30580660; PMCID: PMC6748577.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Cognitive performance in survivors of breast cancer and markers of biological aging. Cancer. 2019 01 15; 125(2):298-306.
Carroll JE, Van Dyk K, Bower JE, Scuric Z, Petersen L, Schiestl R, Irwin MR, Ganz PA. PMID: 30474160; PMCID: PMC7082843.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
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Retraction Note to: Mouse models of intestinal inflammation and cancer. Arch Toxicol. 2018 11; 92(11):3441.
Westbrook AM, Szakmary A, Schiestl RH. PMID: 30267108.
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PubMed Mentions: Fields:
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Glyphosate-based herbicides and cancer risk: a post-IARC decision review of potential mechanisms, policy and avenues of research. Carcinogenesis. 2018 10 08; 39(10):1207-1215.
Davoren MJ, Schiestl RH. PMID: 30060078; PMCID: PMC7530464.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsPHPublic Health
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Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice. Nutrients. 2017 Dec 12; 9(12).
Böhmdorfer M, Szakmary A, Schiestl RH, Vaquero J, Riha J, Brenner S, Thalhammer T, Szekeres T, Jäger W. PMID: 29231856; PMCID: PMC5748797.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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Biomarkers of aging associated with past treatments in breast cancer survivors. NPJ Breast Cancer. 2017; 3:50.
Scuric Z, Carroll JE, Bower JE, Ramos-Perlberg S, Petersen L, Esquivel S, Hogan M, Chapman AM, Irwin MR, Breen EC, Ganz PA, Schiestl R. PMID: 29238750; PMCID: PMC5727230.
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PubMed Mentions:
36
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MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis. Nat Commun. 2016 08 10; 7:12376.
Wang W, Org T, Montel-Hagen A, Pioli PD, Duan D, Israely E, Malkin D, Su T, Flach J, Kurdistani SK, Schiestl RH, Mikkola HK. PMID: 27507714; PMCID: PMC4987520.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Mouse models of intestinal inflammation and cancer. Arch Toxicol. 2016 Sep; 90(9):2109-2130.
Westbrook AM, Szakmary A, Schiestl RH. PMID: 27311821.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis. PLoS One. 2016; 11(4):e0151190.
Cheema AK, Maier I, Dowdy T, Wang Y, Singh R, Ruegger PM, Borneman J, Fornace AJ, Schiestl RH. PMID: 27073845; PMCID: PMC4830457.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Evidence from Animal Models: Is a Restricted or Conventional Intestinal Microbiota Composition Predisposing to Risk for High-LET Radiation Injury? Radiat Res. 2015 Jun; 183(6):589-93.
Maier I, Schiestl RH. PMID: 26010710.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCellsPHPublic Health
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Drug affinity responsive target stability (DARTS) for small-molecule target identification. Methods Mol Biol. 2015; 1263:287-98.
Pai MY, Lomenick B, Hwang H, Schiestl R, McBride W, Loo JA, Huang J. PMID: 25618353; PMCID: PMC4442491.
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PubMed Mentions:
137 Fields:
Translation:
Cells
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Lymphoma caused by intestinal microbiota. Int J Environ Res Public Health. 2014 Sep 01; 11(9):9038-49.
Yamamoto ML, Schiestl RH. PMID: 25257357; PMCID: PMC4199005.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Intestinal microbiome and lymphoma development. Cancer J. 2014 May-Jun; 20(3):190-4.
Yamamoto ML, Schiestl RH. PMID: 24855006; PMCID: PMC4047521.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimals
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Intestinal microbiota reduces genotoxic endpoints induced by high-energy protons. Radiat Res. 2014 Jan; 181(1):45-53.
Maier I, Berry DM, Schiestl RH. PMID: 24397477.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity. Cancer Res. 2013 Jul 15; 73(14):4222-32.
Yamamoto ML, Maier I, Dang AT, Berry D, Liu J, Ruegger PM, Yang JI, Soto PA, Presley LL, Reliene R, Westbrook AM, Wei B, Loy A, Chang C, Braun J, Borneman J, Schiestl RH. PMID: 23860718; PMCID: PMC3718495.
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PubMed Mentions:
49 Fields:
Translation:
AnimalsCells
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Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cells. Mutat Res. 2013 Sep; 749(1-2):58-65.
Yamamoto ML, Chapman AM, Schiestl RH. PMID: 23748015; PMCID: PMC3810249.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCellsPHPublic Health
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Mouse models for efficacy testing of agents against radiation carcinogenesis—a literature review. Int J Environ Res Public Health. 2012 Dec 27; 10(1):107-43.
Rivina L, Schiestl R. PMID: 23271302; PMCID: PMC3564133.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases. PLoS One. 2012; 7(9):e44700.
Cabeza-Arvelaiz Y, Schiestl RH. PMID: 22970289; PMCID: PMC3436760.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity. Environ Mol Mutagen. 2012 Mar; 53(2):94-100.
Sobol Z, Schiestl RH. PMID: 22020802.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Exp Hematol. 2012 Jan; 40(1):3-13.e3.
Hacke K, Szakmary A, Cuddihy AR, Rozengurt N, Lemp NA, Aubrecht J, Lawson GW, Rao NP, Crooks GM, Schiestl RH, Kasahara N. PMID: 22001673; PMCID: PMC4305396.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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The role of tumour necrosis factor-α and tumour necrosis factor receptor signalling in inflammation-associated systemic genotoxicity. Mutagenesis. 2012 Jan; 27(1):77-86.
Westbrook AM, Wei B, Hacke K, Xia M, Braun J, Schiestl RH. PMID: 21980144; PMCID: PMC3241942.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Intestinal inflammation induces genotoxicity to extraintestinal tissues and cell types in mice. Int J Cancer. 2011 Oct 15; 129(8):1815-25.
Westbrook AM, Wei B, Braun J, Schiestl RH. PMID: 21520038; PMCID: PMC3197753.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae. Mol Genet Genomics. 2011 Jun; 285(6):471-84.
Chan CY, Zhu J, Schiestl RH. PMID: 21512733.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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High throughput screening of small molecule libraries for modifiers of radiation responses. Int J Radiat Biol. 2011 Aug; 87(8):839-45.
Kim K, Damoiseaux R, Norris AJ, Rivina L, Bradley K, Jung ME, Gatti RA, Schiestl RH, McBride WH. PMID: 21401317; PMCID: PMC3203687.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg. Cancer Res. 2010 Dec 01; 70(23):9703-10.
Reliene R, Yamamoto ML, Rao PN, Schiestl RH. PMID: 21118969; PMCID: PMC3059244.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Effects of 1 GeV/nucleon ⁵⁶Fe particles on longevity, carcinogenesis and neuromotor ability in Atm-deficient mice. Radiat Res. 2011 Feb; 175(2):231-9.
Yamamoto ML, Hafer K, Reliene R, Fleming S, Kelly O, Hacke K, Schiestl RH. PMID: 21268717.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version. Radiat Res. 2010 Dec; 174(6):719-26.
Hafer K, Rivina Y, Schiestl RH. PMID: 21128795; PMCID: PMC3080456.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice. J Nucl Med. 2010 Aug; 51(8):1285-92.
Walter MA, Hildebrandt IJ, Hacke K, Kesner AL, Kelly O, Lawson GW, Phelps ME, Czernin J, Weber WA, Schiestl RH. PMID: 20660381.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Cell cycle dependence of ionizing radiation-induced DNA deletions and antioxidant radioprotection in Saccharomyces cerevisiae. Radiat Res. 2010 Jun; 173(6):802-8.
Hafer K, Rivina L, Schiestl RH. PMID: 20518659; PMCID: PMC3873222.
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PubMed Mentions:
4 Fields:
Translation:
Animals
-
Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models. Mutat Res. 2010 Jul-Sep; 705(1):40-59.
Westbrook AM, Szakmary A, Schiestl RH. PMID: 20298806; PMCID: PMC2878867.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimals
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Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation. Cancer Res. 2010 Mar 01; 70(5):1875-84.
Westbrook AM, Schiestl RH. PMID: 20179206; PMCID: PMC2831166.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice. Cancer Res. 2009 Nov 15; 69(22):8784-9.
Trouiller B, Reliene R, Westbrook A, Solaimani P, Schiestl RH. PMID: 19887611; PMCID: PMC3873219.
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PubMed Mentions:
150 Fields:
Translation:
AnimalsCells
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More damaging than we think: systemic effects of intestinal inflammation. Cell Cycle. 2009 Aug 15; 8(16):2482-3.
Westbrook AM, Wei B, Braun J, Schiestl RH. PMID: 19657227; PMCID: PMC3753000.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Rad1, rad10 and rad52 mutations reduce the increase of microhomology length during radiation-induced microhomology-mediated illegitimate recombination in saccharomyces cerevisiae. Radiat Res. 2009 Aug; 172(2):141-51.
Chan CY, Schiestl RH. PMID: 19630519; PMCID: PMC2741414.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Intestinal mucosal inflammation leads to systemic genotoxicity in mice. Cancer Res. 2009 Jun 01; 69(11):4827-34.
Westbrook AM, Wei B, Braun J, Schiestl RH. PMID: 19487293; PMCID: PMC2709766.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells. Radiat Res. 2009 Apr; 171(4):454-63.
Scuric Z, Chan CY, Hafer K, Schiestl RH. PMID: 19397446; PMCID: PMC2709764.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals. Mutat Res. 2009 Jun 01; 665(1-2):37-43.
Reliene R, Pollard JM, Sobol Z, Trouiller B, Gatti RA, Schiestl RH. PMID: 19427509.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Pol3 is involved in nonhomologous end-joining in Saccharomyces cerevisiae. DNA Repair (Amst). 2008 Sep 01; 7(9):1531-41.
Chan CY, Galli A, Schiestl RH. PMID: 18606574.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice. Mutat Res. 2008 Sep 26; 644(1-2):11-6.
Yamamoto ML, Reliene R, Oshima J, Schiestl RH. PMID: 18639560.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Experimental antioxidant therapy in ataxia telangiectasia. Clin Med Oncol. 2008; 2:431-6.
Reliene R, Schiestl RH. PMID: 21892312; PMCID: PMC3161695.
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PubMed Mentions:
15
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Refinement of the dichlorofluorescein assay for flow cytometric measurement of reactive oxygen species in irradiated and bystander cell populations. Radiat Res. 2008 Apr; 169(4):460-8.
Hafer K, Iwamoto KS, Schiestl RH. PMID: 18363435.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Radiation-induced long-lived extracellular radicals do not contribute to measurement of intracellular reactive oxygen species using the dichlorofluorescein method. Radiat Res. 2008 Apr; 169(4):469-73.
Hafer K, Konishi T, Schiestl RH. PMID: 18363434.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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9,10-Phenanthrenequinone induces DNA deletions and forward mutations via oxidative mechanisms in the yeast Saccharomyces cerevisiae. Toxicol In Vitro. 2008 Mar; 22(2):296-300.
Rodriguez CE, Sobol Z, Schiestl RH. PMID: 17959352.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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HNO induces DNA deletions in the yeast S. cerevisiae. Mutat Res. 2008 Feb 01; 638(1-2):83-9.
Sobol Z, Cook NM, Schiestl RH. PMID: 17963796.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice. Food Chem Toxicol. 2008 Apr; 46(4):1371-7.
Reliene R, Fleming SM, Chesselet MF, Schiestl RH. PMID: 18037553; PMCID: PMC3107045.
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PubMed Mentions:
17 Fields:
Translation:
Animals
-
Adaptive response to gamma radiation in mammalian cells proficient and deficient in components of nucleotide excision repair. Radiat Res. 2007 Aug; 168(2):168-74.
Hafer K, Iwamoto KS, Iwamoto KK, Scuric Z, Schiestl RH. PMID: 17638404.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae. Nucleic Acids Res. 2007; 35(15):5051-9.
Chan CY, Kiechle M, Manivasakam P, Schiestl RH. PMID: 17652322; PMCID: PMC1976441.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Development of a microtiter plate version of the yeast DEL assay amenable to high-throughput toxicity screening of chemical libraries. Mutat Res. 2007 Dec 01; 634(1-2):228-34.
Hontzeas N, Hafer K, Schiestl RH. PMID: 17707690.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Antioxidants suppress lymphoma and increase longevity in Atm-deficient mice. J Nutr. 2007 01; 137(1 Suppl):229S-232S.
Reliene R, Schiestl RH. PMID: 17182831.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
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Involvement of homologous recombination in carcinogenesis. Adv Genet. 2007; 58:67-87.
Reliene R, Bishop AJ, Schiestl RH. PMID: 17452246.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine. DNA Repair (Amst). 2006 Nov 08; 5(11):1392-7.
Reliene R, Goad ME, Schiestl RH. PMID: 16916625.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice. DNA Repair (Amst). 2006 Jul 13; 5(7):852-9.
Reliene R, Schiestl RH. PMID: 16781197.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimalsCells
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Point-source irradiation with eccentric rotation causes inhomogeneous dose distribution. Radiat Res. 2006 May; 165(5):616-20.
Hafer K, Scuric Z, Iwamoto KS, Schiestl RH. PMID: 16669744.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Carcinogenic Cr(VI) and the nutritional supplement Cr(III) induce DNA deletions in yeast and mice. Cancer Res. 2006 Apr 01; 66(7):3480-4.
Kirpnick-Sobol Z, Reliene R, Schiestl RH. PMID: 16585171.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. Carcinogenesis. 2006 Feb; 27(2):240-4.
Reliene R, Schiestl RH. PMID: 16162646.
View in:
PubMed Mentions:
40 Fields:
Translation:
Animals
-
Yeast DEL assay detects clastogens. Mutat Res. 2005 Apr 04; 582(1-2):116-34.
Kirpnick Z, Homiski M, Rubitski E, Repnevskaya M, Howlett N, Aubrecht J, Schiestl RH. PMID: 15781217.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Diesel exhaust particles cause increased levels of DNA deletions after transplacental exposure in mice. Mutat Res. 2005 Mar 01; 570(2):245-52.
Reliene R, Hlavacova A, Mahadevan B, Baird WM, Schiestl RH. PMID: 15708583.
View in:
PubMed Mentions:
13 Fields:
Translation:
Animals
-
Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res. 2004 Aug 01; 64(15):5148-53.
Reliene R, Fischer E, Schiestl RH. PMID: 15289318.
View in:
PubMed Mentions:
55 Fields:
Translation:
Animals
-
Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice. DNA Repair (Amst). 2004 Feb 03; 3(2):103-11.
Reliene R, Bishop AJ, Li G, Schiestl RH. PMID: 14706343.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer. Methods Mol Biol. 2004; 262:125-39.
Reliene R, Bishop AJ, Aubrecht J, Schiestl RH. PMID: 14769959.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Mouse models for induced genetic instability at endogenous loci. Oncogene. 2003 Oct 13; 22(45):7000-10.
Reliene R, Schiestl RH. PMID: 14557804.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Promoter-trapping in Saccharomyces cerevisiae by radiation-assisted fragment insertion. Nucleic Acids Res. 2002 Dec 15; 30(24):e136.
Kiechle M, Manivasakam P, Eckardt-Schupp F, Schiestl RH, Friedl AA. PMID: 12490727; PMCID: PMC140085.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells