Robert H Schiestl

Title(s)Professor Emeritus, Pathology and Laboratory Medicine
SchoolMedicine
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    Mechanisms of Intestinal Inflammation - Associated Systemic Genotoxicity
    NIH R56AI094756Sep 21, 2012 - Aug 31, 2014
    Role: Principal Investigator
    Effect of Particulate Matter on DNA Deletions in Mice
    NIH R03TW007166Feb 15, 2006 - Jan 31, 2009
    Role: Principal Investigator
    Effect of parkin on DNA damage induced rearrangements
    NIH R21ES013547Jun 16, 2005 - May 30, 2008
    Role: Principal Investigator
    Effect of Diesel Exhaust Particles on DNA Deletions
    NIH R21ES013713May 20, 2005 - Apr 30, 2008
    Role: Principal Investigator
    MECHANISM OF RADIATION INDUCED DELAYED GENOTOXICITY
    NIH R01CA082473Sep 17, 1999 - Jun 30, 2004
    Role: Principal Investigator
    Antioxidant Therapy for Ataxia Telangiectasia
    NIH R01ES009519Jun 1, 1999 - May 31, 2010
    Role: Principal Investigator
    DEVELOPMENT AND VALIDATION OF THE YEAST DEL ASSAY
    NIH R41ES009038Sep 30, 1997 - Dec 31, 1998
    Role: Principal Investigator
    CARCINOGEN INDUCED DELETIONS IN VIVO AND IN VITRO
    NIH K02ES000299May 1, 1996 - Apr 30, 2001
    Role: Principal Investigator
    CARCINOGEN INDUCED DELETIONS
    NIH R01ES007694Aug 1, 1995 - Jul 31, 1999
    Role: Principal Investigator
    BIOLOGICAL RESPONSES TO OZONE EXPOSURE
    NIH R01ES006593Aug 1, 1993 - Jul 31, 1997
    Role: Principal Investigator
    CONSTRUCTION OF A SHORT TERM TEST TO DETECT CARCINOGENS
    NIH R03RR008112Sep 30, 1992 - Sep 29, 1993
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Particle Radiation Side-Effects: Intestinal Microbiota Composition Shapes Interferon-γ-Induced Osteo-Immunogenicity. Radiat Res. 2022 Feb 01; 197(2):184-192. Maier I, Ruegger PM, Deutschmann J, Helbich TH, Pietschmann P, Schiestl RH, Borneman J. PMID: 35130347.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    2. Cyanovirin-N Binds Viral Envelope Proteins at the Low-Affinity Carbohydrate Binding Site without Direct Virus Neutralization Ability. Molecules. 2021 Jun 13; 26(12). Maier I, Schiestl RH, Kontaxis G. PMID: 34199200; PMCID: PMC8231982.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    3. Intestinal bacterial indicator phylotypes associate with impaired DNA double-stranded break sensors but augmented skeletal bone micro-structure. Carcinogenesis. 2020 06 17; 41(4):483-489. Maier I, Liu J, Ruegger PM, Deutschmann J, Patsch JM, Helbich TH, Borneman J, Schiestl RH. PMID: 31840161; PMCID: PMC7456343.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    4. Mannosylated hemagglutinin peptides bind cyanovirin-N independent of disulfide-bonds in complementary binding sites. RSC Adv. 2020 Mar 16; 10(19):11079-11087. Schilling PE, Kontaxis G, Dragosits M, Schiestl RH, Becker CFW, Maier I. PMID: 35495330; PMCID: PMC9050506.
      View in: PubMed   Mentions: 3  
    5. A novel probiotic, Lactobacillus johnsonii 456, resists acid and can persist in the human gut beyond the initial ingestion period. Gut Microbes. 2019; 10(4):458-480. Davoren MJ, Liu J, Castellanos J, Rodríguez-Malavé NI, Schiestl RH. PMID: 30580660; PMCID: PMC6748577.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    6. Cognitive performance in survivors of breast cancer and markers of biological aging. Cancer. 2019 01 15; 125(2):298-306. Carroll JE, Van Dyk K, Bower JE, Scuric Z, Petersen L, Schiestl R, Irwin MR, Ganz PA. PMID: 30474160; PMCID: PMC7082843.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    7. Retraction Note to: Mouse models of intestinal inflammation and cancer. Arch Toxicol. 2018 11; 92(11):3441. Westbrook AM, Szakmary A, Schiestl RH. PMID: 30267108.
      View in: PubMed   Mentions:    Fields:    
    8. Glyphosate-based herbicides and cancer risk: a post-IARC decision review of potential mechanisms, policy and avenues of research. Carcinogenesis. 2018 10 08; 39(10):1207-1215. Davoren MJ, Schiestl RH. PMID: 30060078; PMCID: PMC7530464.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsPHPublic Health
    9. Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice. Nutrients. 2017 Dec 12; 9(12). Böhmdorfer M, Szakmary A, Schiestl RH, Vaquero J, Riha J, Brenner S, Thalhammer T, Szekeres T, Jäger W. PMID: 29231856; PMCID: PMC5748797.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    10. Biomarkers of aging associated with past treatments in breast cancer survivors. NPJ Breast Cancer. 2017; 3:50. Scuric Z, Carroll JE, Bower JE, Ramos-Perlberg S, Petersen L, Esquivel S, Hogan M, Chapman AM, Irwin MR, Breen EC, Ganz PA, Schiestl R. PMID: 29238750; PMCID: PMC5727230.
      View in: PubMed   Mentions: 37  
    11. MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis. Nat Commun. 2016 08 10; 7:12376. Wang W, Org T, Montel-Hagen A, Pioli PD, Duan D, Israely E, Malkin D, Su T, Flach J, Kurdistani SK, Schiestl RH, Mikkola HK. PMID: 27507714; PMCID: PMC4987520.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    12. Mouse models of intestinal inflammation and cancer. Arch Toxicol. 2016 Sep; 90(9):2109-2130. Westbrook AM, Szakmary A, Schiestl RH. PMID: 27311821.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    13. Mouse models for radiation-induced cancers. Mutagenesis. 2016 09; 31(5):491-509. Rivina L, Davoren MJ, Schiestl RH. PMID: 27209205; PMCID: PMC6280996.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    14. Chemopreventive Metabolites Are Correlated with a Change in Intestinal Microbiota Measured in A-T Mice and Decreased Carcinogenesis. PLoS One. 2016; 11(4):e0151190. Cheema AK, Maier I, Dowdy T, Wang Y, Singh R, Ruegger PM, Borneman J, Fornace AJ, Schiestl RH. PMID: 27073845; PMCID: PMC4830457.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    15. Requirement of POL3 and POL4 on non-homologous and microhomology-mediated end joining in rad50/xrs2 mutants of Saccharomyces cerevisiae. Mutagenesis. 2015 Nov; 30(6):841-9. Galli A, Chan CY, Parfenova L, Cervelli T, Schiestl RH. PMID: 26122113; PMCID: PMC4757936.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    16. Evidence from Animal Models: Is a Restricted or Conventional Intestinal Microbiota Composition Predisposing to Risk for High-LET Radiation Injury? Radiat Res. 2015 Jun; 183(6):589-93. Maier I, Schiestl RH. PMID: 26010710.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    17. Drug affinity responsive target stability (DARTS) for small-molecule target identification. Methods Mol Biol. 2015; 1263:287-98. Pai MY, Lomenick B, Hwang H, Schiestl R, McBride W, Loo JA, Huang J. PMID: 25618353; PMCID: PMC4442491.
      View in: PubMed   Mentions: 157     Fields:    Translation:Cells
    18. IL-13 overexpression in mouse lungs triggers systemic genotoxicity in peripheral blood. Mutat Res. 2014 Nov; 769:100-7. Chapmana AM, Malkin DJ, Camacho J, Schiestl RH. PMID: 25400503; PMCID: PMC4228791.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    19. Lymphoma caused by intestinal microbiota. Int J Environ Res Public Health. 2014 Sep 01; 11(9):9038-49. Yamamoto ML, Schiestl RH. PMID: 25257357; PMCID: PMC4199005.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    20. Radiation-induced myeloid leukemia in murine models. Hum Genomics. 2014 Jul 25; 8:13. Rivina L, Davoren M, Schiestl RH. PMID: 25062865; PMCID: PMC4128013.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsPHPublic Health
    21. Intestinal microbiome and lymphoma development. Cancer J. 2014 May-Jun; 20(3):190-4. Yamamoto ML, Schiestl RH. PMID: 24855006; PMCID: PMC4047521.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    22. Intestinal microbiota reduces genotoxic endpoints induced by high-energy protons. Radiat Res. 2014 Jan; 181(1):45-53. Maier I, Berry DM, Schiestl RH. PMID: 24397477.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    23. Intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity. Cancer Res. 2013 Jul 15; 73(14):4222-32. Yamamoto ML, Maier I, Dang AT, Berry D, Liu J, Ruegger PM, Yang JI, Soto PA, Presley LL, Reliene R, Westbrook AM, Wei B, Loy A, Chang C, Braun J, Borneman J, Schiestl RH. PMID: 23860718; PMCID: PMC3718495.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    24. Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cells. Mutat Res. 2013 Sep; 749(1-2):58-65. Yamamoto ML, Chapman AM, Schiestl RH. PMID: 23748015; PMCID: PMC3810249.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCellsPHPublic Health
    25. Mouse models of radiation-induced cancers. Adv Genet. 2013; 84:83-122. Rivina L, Schiestl R. PMID: 24262097.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    26. Mouse models for efficacy testing of agents against radiation carcinogenesis—a literature review. Int J Environ Res Public Health. 2012 Dec 27; 10(1):107-43. Rivina L, Schiestl R. PMID: 23271302; PMCID: PMC3564133.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    27. Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases. PLoS One. 2012; 7(9):e44700. Cabeza-Arvelaiz Y, Schiestl RH. PMID: 22970289; PMCID: PMC3436760.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    28. Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons. Mol Neurodegener. 2011 Dec 13; 6:83. Cabeza-Arvelaiz Y, Fleming SM, Richter F, Masliah E, Chesselet MF, Schiestl RH. PMID: 22165993; PMCID: PMC3271045.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    29. Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity. Environ Mol Mutagen. 2012 Mar; 53(2):94-100. Sobol Z, Schiestl RH. PMID: 22020802.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    30. Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Exp Hematol. 2012 Jan; 40(1):3-13.e3. Hacke K, Szakmary A, Cuddihy AR, Rozengurt N, Lemp NA, Aubrecht J, Lawson GW, Rao NP, Crooks GM, Schiestl RH, Kasahara N. PMID: 22001673; PMCID: PMC4305396.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    31. The role of tumour necrosis factor-α and tumour necrosis factor receptor signalling in inflammation-associated systemic genotoxicity. Mutagenesis. 2012 Jan; 27(1):77-86. Westbrook AM, Wei B, Hacke K, Xia M, Braun J, Schiestl RH. PMID: 21980144; PMCID: PMC3241942.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    32. Intestinal inflammation induces genotoxicity to extraintestinal tissues and cell types in mice. Int J Cancer. 2011 Oct 15; 129(8):1815-25. Westbrook AM, Wei B, Braun J, Schiestl RH. PMID: 21520038; PMCID: PMC3197753.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    33. A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro. Drug Chem Toxicol. 2011 Oct; 34(4):433-9. Aubrecht J, Goad ME, Czopik AK, Lerner CP, Johnson KA, Simpson EM, Schiestl RH. PMID: 21740348.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    34. Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae. Mol Genet Genomics. 2011 Jun; 285(6):471-84. Chan CY, Zhu J, Schiestl RH. PMID: 21512733.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    35. High throughput screening of small molecule libraries for modifiers of radiation responses. Int J Radiat Biol. 2011 Aug; 87(8):839-45. Kim K, Damoiseaux R, Norris AJ, Rivina L, Bradley K, Jung ME, Gatti RA, Schiestl RH, McBride WH. PMID: 21401317; PMCID: PMC3203687.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    36. Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg. Cancer Res. 2010 Dec 01; 70(23):9703-10. Reliene R, Yamamoto ML, Rao PN, Schiestl RH. PMID: 21118969; PMCID: PMC3059244.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    37. Effects of 1 GeV/nucleon ⁵⁶Fe particles on longevity, carcinogenesis and neuromotor ability in Atm-deficient mice. Radiat Res. 2011 Feb; 175(2):231-9. Yamamoto ML, Hafer K, Reliene R, Fleming S, Kelly O, Hacke K, Schiestl RH. PMID: 21268717.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    38. Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version. Radiat Res. 2010 Dec; 174(6):719-26. Hafer K, Rivina Y, Schiestl RH. PMID: 21128795; PMCID: PMC3080456.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    39. New and emerging technologies for genetic toxicity testing. Environ Mol Mutagen. 2011 Apr; 52(3):205-23. Lynch AM, Sasaki JC, Elespuru R, Jacobson-Kram D, Thybaud V, De Boeck M, Aardema MJ, Aubrecht J, Benz RD, Dertinger SD, Douglas GR, White PA, Escobar PA, Fornace A, Honma M, Naven RT, Rusling JF, Schiestl RH, Walmsley RM, Yamamura E, van Benthem J, Kim JH. PMID: 20740635.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    40. Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae. Mol Genet Genomics. 2010 Oct; 284(4):231-42. Friedl AA, Kiechle M, Maxeiner HG, Schiestl RH, Eckardt-Schupp F. PMID: 20677012; PMCID: PMC2939329.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    41. Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice. J Nucl Med. 2010 Aug; 51(8):1285-92. Walter MA, Hildebrandt IJ, Hacke K, Kesner AL, Kelly O, Lawson GW, Phelps ME, Czernin J, Weber WA, Schiestl RH. PMID: 20660381.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    42. Cell cycle dependence of ionizing radiation-induced DNA deletions and antioxidant radioprotection in Saccharomyces cerevisiae. Radiat Res. 2010 Jun; 173(6):802-8. Hafer K, Rivina L, Schiestl RH. PMID: 20518659; PMCID: PMC3873222.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    43. Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models. Mutat Res. 2010 Jul-Sep; 705(1):40-59. Westbrook AM, Szakmary A, Schiestl RH. PMID: 20298806; PMCID: PMC2878867.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimals
    44. Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation. Cancer Res. 2010 Mar 01; 70(5):1875-84. Westbrook AM, Schiestl RH. PMID: 20179206; PMCID: PMC2831166.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    45. Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice. Cancer Res. 2009 Nov 15; 69(22):8784-9. Trouiller B, Reliene R, Westbrook A, Solaimani P, Schiestl RH. PMID: 19887611; PMCID: PMC3873219.
      View in: PubMed   Mentions: 151     Fields:    Translation:AnimalsCells
    46. The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in Saccharomyces cerevisiae is RAD50 dependent. J Biomed Biotechnol. 2009; 2009:312710. Galli A, Hafer K, Cervelli T, Schiestl RH. PMID: 19834566; PMCID: PMC2761004.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    47. More damaging than we think: systemic effects of intestinal inflammation. Cell Cycle. 2009 Aug 15; 8(16):2482-3. Westbrook AM, Wei B, Braun J, Schiestl RH. PMID: 19657227; PMCID: PMC3753000.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    48. Rad1, rad10 and rad52 mutations reduce the increase of microhomology length during radiation-induced microhomology-mediated illegitimate recombination in saccharomyces cerevisiae. Radiat Res. 2009 Aug; 172(2):141-51. Chan CY, Schiestl RH. PMID: 19630519; PMCID: PMC2741414.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    49. Intestinal mucosal inflammation leads to systemic genotoxicity in mice. Cancer Res. 2009 Jun 01; 69(11):4827-34. Westbrook AM, Wei B, Braun J, Schiestl RH. PMID: 19487293; PMCID: PMC2709766.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    50. Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells. Radiat Res. 2009 Apr; 171(4):454-63. Scuric Z, Chan CY, Hafer K, Schiestl RH. PMID: 19397446; PMCID: PMC2709764.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    51. N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals. Mutat Res. 2009 Jun 01; 665(1-2):37-43. Reliene R, Pollard JM, Sobol Z, Trouiller B, Gatti RA, Schiestl RH. PMID: 19427509.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    52. Biological aspects of dichlorofluorescein measurement of cellular reactive oxygen species. Radiat Res. 2008 Sep; 170(3):408. Hafer K, Schiestl RH. PMID: 18763872.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    53. Pol3 is involved in nonhomologous end-joining in Saccharomyces cerevisiae. DNA Repair (Amst). 2008 Sep 01; 7(9):1531-41. Chan CY, Galli A, Schiestl RH. PMID: 18606574.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    54. Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice. Mutat Res. 2008 Sep 26; 644(1-2):11-6. Yamamoto ML, Reliene R, Oshima J, Schiestl RH. PMID: 18639560.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    55. Experimental antioxidant therapy in ataxia telangiectasia. Clin Med Oncol. 2008; 2:431-6. Reliene R, Schiestl RH. PMID: 21892312; PMCID: PMC3161695.
      View in: PubMed   Mentions: 15  
    56. Refinement of the dichlorofluorescein assay for flow cytometric measurement of reactive oxygen species in irradiated and bystander cell populations. Radiat Res. 2008 Apr; 169(4):460-8. Hafer K, Iwamoto KS, Schiestl RH. PMID: 18363435.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    57. Radiation-induced long-lived extracellular radicals do not contribute to measurement of intracellular reactive oxygen species using the dichlorofluorescein method. Radiat Res. 2008 Apr; 169(4):469-73. Hafer K, Konishi T, Schiestl RH. PMID: 18363434.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    58. Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes. Dev Neurobiol. 2008 Feb 01; 68(2):265-73. Chen X, Watkins R, Delot E, Reliene R, Schiestl RH, Burgoyne PS, Arnold AP. PMID: 18004765.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    59. 9,10-Phenanthrenequinone induces DNA deletions and forward mutations via oxidative mechanisms in the yeast Saccharomyces cerevisiae. Toxicol In Vitro. 2008 Mar; 22(2):296-300. Rodriguez CE, Sobol Z, Schiestl RH. PMID: 17959352.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    60. HNO induces DNA deletions in the yeast S. cerevisiae. Mutat Res. 2008 Feb 01; 638(1-2):83-9. Sobol Z, Cook NM, Schiestl RH. PMID: 17963796.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    61. Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice. Food Chem Toxicol. 2008 Apr; 46(4):1371-7. Reliene R, Fleming SM, Chesselet MF, Schiestl RH. PMID: 18037553; PMCID: PMC3107045.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    62. Adaptive response to gamma radiation in mammalian cells proficient and deficient in components of nucleotide excision repair. Radiat Res. 2007 Aug; 168(2):168-74. Hafer K, Iwamoto KS, Iwamoto KK, Scuric Z, Schiestl RH. PMID: 17638404.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    63. Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae. Nucleic Acids Res. 2007; 35(15):5051-9. Chan CY, Kiechle M, Manivasakam P, Schiestl RH. PMID: 17652322; PMCID: PMC1976441.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    64. Development of a microtiter plate version of the yeast DEL assay amenable to high-throughput toxicity screening of chemical libraries. Mutat Res. 2007 Dec 01; 634(1-2):228-34. Hontzeas N, Hafer K, Schiestl RH. PMID: 17707690.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    65. Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment. Toxicol Sci. 2007 Sep; 99(1):20-5. Ku WW, Aubrecht J, Mauthe RJ, Schiestl RH, Fornace AJ. PMID: 17548889.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    66. Microtiter plate transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1):5-8. Gietz RD, Schiestl RH. PMID: 17401331.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    67. Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1):35-7. Gietz RD, Schiestl RH. PMID: 17401335.
      View in: PubMed   Mentions: 225     Fields:    Translation:AnimalsCells
    68. Large-scale high-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1):38-41. Gietz RD, Schiestl RH. PMID: 17401336.
      View in: PubMed   Mentions: 185     Fields:    Translation:AnimalsCells
    69. Frozen competent yeast cells that can be transformed with high efficiency using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1):1-4. Gietz RD, Schiestl RH. PMID: 17401330.
      View in: PubMed   Mentions: 166     Fields:    Translation:AnimalsCells
    70. High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc. 2007; 2(1):31-4. Gietz RD, Schiestl RH. PMID: 17401334.
      View in: PubMed   Mentions: 1393     Fields:    Translation:AnimalsCells
    71. Antioxidants suppress lymphoma and increase longevity in Atm-deficient mice. J Nutr. 2007 01; 137(1 Suppl):229S-232S. Reliene R, Schiestl RH. PMID: 17182831.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    72. Involvement of homologous recombination in carcinogenesis. Adv Genet. 2007; 58:67-87. Reliene R, Bishop AJ, Schiestl RH. PMID: 17452246.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    73. Heat-induced phosphorylation of NBS1 in human skin fibroblast cells. J Cell Biochem. 2006 Dec 15; 99(6):1642-50. Ohnishi K, Scuric Z, Yau D, Schiestl RH, Okamoto N, Takahashi A, Ohnishi T. PMID: 16823774.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    74. siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status. Radiat Res. 2006 Sep; 166(3):454-62. Ohnishi K, Scuric Z, Schiestl RH, Okamoto N, Takahashi A, Ohnishi T. PMID: 16972754.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    75. Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine. DNA Repair (Amst). 2006 Nov 08; 5(11):1392-7. Reliene R, Goad ME, Schiestl RH. PMID: 16916625.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    76. Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice. DNA Repair (Amst). 2006 Jul 13; 5(7):852-9. Reliene R, Schiestl RH. PMID: 16781197.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    77. Point-source irradiation with eccentric rotation causes inhomogeneous dose distribution. Radiat Res. 2006 May; 165(5):616-20. Hafer K, Scuric Z, Iwamoto KS, Schiestl RH. PMID: 16669744.
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    78. Differences in animal housing facilities and diet may affect study outcomes-a plea for inclusion of such information in publications. DNA Repair (Amst). 2006 Jun 10; 5(6):651-3. Reliene R, Schiestl RH. PMID: 16581314.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    79. Carcinogenic Cr(VI) and the nutritional supplement Cr(III) induce DNA deletions in yeast and mice. Cancer Res. 2006 Apr 01; 66(7):3480-4. Kirpnick-Sobol Z, Reliene R, Schiestl RH. PMID: 16585171.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    80. Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients. DNA Repair (Amst). 2006 Feb 03; 5(2):251-7. Howlett NG, Scuric Z, D'Andrea AD, Schiestl RH. PMID: 16309973.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    81. Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. Carcinogenesis. 2006 Feb; 27(2):240-4. Reliene R, Schiestl RH. PMID: 16162646.
      View in: PubMed   Mentions: 40     Fields:    Translation:Animals
    82. Effect of benzene and its closed ring metabolites on intrachromosomal recombination in Saccharomyces cerevisiae. Mutat Res. 2006 Jan 29; 593(1-2):1-8. Sommers CH, Schiestl RH. PMID: 16154601.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    83. Yeast DEL assay detects clastogens. Mutat Res. 2005 Apr 04; 582(1-2):116-34. Kirpnick Z, Homiski M, Rubitski E, Repnevskaya M, Howlett N, Aubrecht J, Schiestl RH. PMID: 15781217.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    84. Diesel exhaust particles cause increased levels of DNA deletions after transplacental exposure in mice. Mutat Res. 2005 Mar 01; 570(2):245-52. Reliene R, Hlavacova A, Mahadevan B, Baird WM, Schiestl RH. PMID: 15708583.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    85. Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res. 2004 Dec; 162(6):711-28. Stone HB, Moulder JE, Coleman CN, Ang KK, Anscher MS, Barcellos-Hoff MH, Dynan WS, Fike JR, Grdina DJ, Greenberger JS, Hauer-Jensen M, Hill RP, Kolesnick RN, Macvittie TJ, Marks C, McBride WH, Metting N, Pellmar T, Purucker M, Robbins ME, Schiestl RH, Seed TM, Tomaszewski JE, Travis EL, Wallner PE, Wolpert M, Zaharevitz D. PMID: 15548121.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansAnimalsPHPublic Health
    86. Mutagen X and chlorinated tap water are recombinagenic in yeast. Mutat Res. 2004 Oct 10; 563(2):159-69. Egorov AI, Howlett NG, Schiestl RH. PMID: 15364282.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    87. Increases in oxidative stress in the progeny of X-irradiated cells. Radiat Res. 2004 Oct; 162(4):416-25. Rugo RE, Schiestl RH. PMID: 15447041.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    88. Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res. 2004 Aug 01; 64(15):5148-53. Reliene R, Fischer E, Schiestl RH. PMID: 15289318.
      View in: PubMed   Mentions: 55     Fields:    Translation:Animals
    89. 2-Dodecylcyclobutanone does not induce mutations in the Salmonella mutagenicity test or intrachromosomal recombination in Saccharomyces cerevisiae. J Food Prot. 2004 Jun; 67(6):1293-8. Sommers CH, Schiestl RH. PMID: 15222568.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    90. Nucleotide excision repair deficiency causes elevated levels of chromosome gain in Saccharomyces cerevisiae. DNA Repair (Amst). 2004 Feb 03; 3(2):127-34. Howlett NG, Schiestl RH. PMID: 14706346.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    91. Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice. DNA Repair (Amst). 2004 Feb 03; 3(2):103-11. Reliene R, Bishop AJ, Li G, Schiestl RH. PMID: 14706343.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    92. In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer. Methods Mol Biol. 2004; 262:125-39. Reliene R, Bishop AJ, Aubrecht J, Schiestl RH. PMID: 14769959.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    93. Detecting carcinogens with the yeast DEL assay. Methods Mol Biol. 2004; 262:111-24. Brennan RJ, Schiestl RH. PMID: 14769958.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    94. Mouse models for induced genetic instability at endogenous loci. Oncogene. 2003 Oct 13; 22(45):7000-10. Reliene R, Schiestl RH. PMID: 14557804.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    95. Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development. Cancer Res. 2003 Sep 01; 63(17):5335-43. Bishop AJ, Hollander MC, Kosaras B, Sidman RL, Fornace AJ, Schiestl RH. PMID: 14500365.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    96. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair. Aging Cell. 2003 08; 2(4):191-9. Chen L, Huang S, Lee L, Davalos A, Schiestl RH, Campisi J, Oshima J. PMID: 12934712.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    97. Characterization of the hyperrecombination phenotype of the pol3-t mutation of Saccharomyces cerevisiae. Genetics. 2003 May; 164(1):65-79. Galli A, Cervelli T, Schiestl RH. PMID: 12750321; PMCID: PMC1462548.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    98. Role of homologous recombination in carcinogenesis. Exp Mol Pathol. 2003 Apr; 74(2):94-105. Bishop AJ, Schiestl RH. PMID: 12710940.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    99. Promoter-trapping in Saccharomyces cerevisiae by radiation-assisted fragment insertion. Nucleic Acids Res. 2002 Dec 15; 30(24):e136. Kiechle M, Manivasakam P, Eckardt-Schupp F, Schiestl RH, Friedl AA. PMID: 12490727; PMCID: PMC140085.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    100. Detection of Arabidopsis thaliana AtRAD1 cDNA variants and assessment of function by expression in a yeast rad1 mutant. Gene. 2002 Aug 21; 296(1-2):1-9. Vonarx EJ, Howlett NG, Schiestl RH, Kunz BA. PMID: 12383497.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    101. Lack of WRN results in extensive deletion at nonhomologous joining ends. Cancer Res. 2002 Jan 15; 62(2):547-51. Oshima J, Huang S, Pae C, Campisi J, Schiestl RH. PMID: 11809708.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    102. DNA Damage, Repair, and Diseases. J Biomed Biotechnol. 2002; 2(2):45. Wiesmüller L, Ford JM, Schiestl RH. PMID: 12488582; PMCID: PMC153783.
      View in: PubMed   Mentions: 7     Fields:    
    103. Homologous Recombination and Its Role in Carcinogenesis. J Biomed Biotechnol. 2002; 2(2):75-85. Bishop AJ, Schiestl RH. PMID: 12488587; PMCID: PMC153790.
      View in: PubMed   Mentions: 26     Fields:    
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