Ameya S Champhekar

Title(s)Assistant Adjunct Professor, Medicine
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Melanoma dedifferentiation induced by IFN-γ epigenetic remodeling in response to anti-PD-1 therapy. J Clin Invest. 2021 06 15; 131(12). Kim YJ, Sheu KM, Tsoi J, Abril-Rodriguez G, Medina E, Grasso CS, Torrejon DY, Champhekar AS, Litchfield K, Swanton C, Speiser DE, Scumpia PO, Hoffmann A, Graeber TG, Puig-Saus C, Ribas A. PMID: 33914706.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    2. Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma. Cancer Cell. 2021 Jan 11; 39(1):122. Grasso CS, Tsoi J, Onyshchenko M, Abril-Rodriguez G, Ross-Macdonald P, Wind-Rotolo M, Champhekar A, Medina E, Torrejon DY, Shin DS, Tran P, Kim YJ, Puig-Saus C, Campbell K, Vega-Crespo A, Quist M, Martignier C, Luke JJ, Wolchok JD, Johnson DB, Chmielowski B, Hodi FS, Bhatia S, Sharfman W, Urba WJ, Slingluff CL, Diab A, Haanen JBAG, Algarra SM, Pardoll DM, Anagnostou V, Topalian SL, Velculescu VE, Speiser DE, Kalbasi A, Ribas A. PMID: 33306984.
      View in: PubMed   Mentions: 2     Fields:    
    3. Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma. Cancer Cell. 2020 10 12; 38(4):500-515.e3. Grasso CS, Tsoi J, Onyshchenko M, Abril-Rodriguez G, Ross-Macdonald P, Wind-Rotolo M, Champhekar A, Medina E, Torrejon DY, Shin DS, Tran P, Kim YJ, Puig-Saus C, Campbell K, Vega-Crespo A, Quist M, Martignier C, Luke JJ, Wolchok JD, Johnson DB, Chmielowski B, Hodi FS, Bhatia S, Sharfman W, Urba WJ, Slingluff CL, Diab A, Haanen JBAG, Algarra SM, Pardoll DM, Anagnostou V, Topalian SL, Velculescu VE, Speiser DE, Kalbasi A, Ribas A. PMID: 32916126.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    4. Overcoming Genetically Based Resistance Mechanisms to PD-1 Blockade. Cancer Discov. 2020 08; 10(8):1140-1157. Torrejon DY, Abril-Rodriguez G, Champhekar AS, Tsoi J, Campbell KM, Kalbasi A, Parisi G, Zaretsky JM, Garcia-Diaz A, Puig-Saus C, Cheung-Lau G, Wohlwender T, Krystofinski P, Vega-Crespo A, Lee CM, Mascaro P, Grasso CS, Berent-Maoz B, Comin-Anduix B, Hu-Lieskovan S, Ribas A. PMID: 32467343.
      View in: PubMed   Mentions: 11     Fields:    
    5. IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System. Clin Cancer Res. 2019 02 01; 25(3):1000-1011. Puig-Saus C, Parisi G, Garcia-Diaz A, Krystofinski PE, Sandoval S, Zhang R, Champhekar AS, McCabe J, Cheung-Lau GC, Truong NA, Vega-Crespo A, Komenan MDS, Pang J, Macabali MH, Saco JD, Goodwin JL, Bolon B, Seet CS, Montel-Hagen A, Crooks GM, Hollis RP, Campo-Fernandez B, Bischof D, Cornetta K, Gschweng EH, Adelson C, Nguyen A, Yang L, Witte ON, Baltimore D, Comin-Anduix B, Kohn DB, Wang X, Cabrera P, Kaplan-Lefko PJ, Berent-Maoz B, Ribas A. PMID: 30409823.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    6. Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral Persistence. PLoS Pathog. 2016 Jan; 12(1):e1005356. Cunningham CR, Champhekar A, Tullius MV, Dillon BJ, Zhen A, de la Fuente JR, Herskovitz J, Elsaesser H, Snell LM, Wilson EB, de la Torre JC, Kitchen SG, Horwitz MA, Bensinger SJ, Smale ST, Brooks DG. PMID: 26808628.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    7. Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control. Adv Immunol. 2016; 129:109-74. Rothenberg EV, Ungerbäck J, Champhekar A. PMID: 26791859.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    8. Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1. Genes Dev. 2015 Apr 15; 29(8):832-48. Champhekar A, Damle SS, Freedman G, Carotta S, Nutt SL, Rothenberg EV. PMID: 25846797.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    9. GATA-3 dose-dependent checkpoints in early T cell commitment. J Immunol. 2014 Oct 01; 193(7):3470-91. Scripture-Adams DD, Damle SS, Li L, Elihu KJ, Qin S, Arias AM, Butler RR, Champhekar A, Zhang JA, Rothenberg EV. PMID: 25172496.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    10. Transcriptional establishment of cell-type identity: dynamics and causal mechanisms of T-cell lineage commitment. Cold Spring Harb Symp Quant Biol. 2013; 78:31-41. Rothenberg EV, Champhekar A, Damle S, Del Real MM, Kueh HY, Li L, Yui MA. PMID: 24135716.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    11. Positive feedback between PU.1 and the cell cycle controls myeloid differentiation. Science. 2013 Aug 09; 341(6146):670-3. Kueh HY, Champhekar A, Champhekhar A, Nutt SL, Elowitz MB, Rothenberg EV. PMID: 23868921.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    12. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood. 2008 Sep 01; 112(5):1813-21. Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA. PMID: 18550850.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    13. Differential control of peripheral circadian rhythms by suprachiasmatic-dependent neural signals. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):3111-6. Guo H, Brewer JM, Champhekar A, Harris RB, Bittman EL. PMID: 15710878.
      View in: PubMed   Mentions: 73     Fields:    Translation:Animals
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