Michael B Elowitz

Title(s)Assistant Adjunct Professor, Biological Chemistry
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Dynamics of chromosome organization and chromatin states in single cells
    NIH U01DK127420Sep 19, 2020 - Jun 30, 2025
    Role: Co-Principal Investigator
    Cell targeting with synthetic sense-and-respond protease circuits
    NIH R01EB030015Sep 1, 2020 - May 31, 2024
    Role: Principal Investigator
    MEMOIR: Recording, and in situ readout of cell lineage and transcriptional history
    NIH R01MH116508Sep 20, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Deciphering the Dynamic Notch Signaling Code
    NIH R01HD075335Sep 26, 2012 - Feb 28, 2025
    Role: Principal Investigator
    Genetic Interactions and Synthetic Population Biology
    NIH R01GM086793Sep 1, 2010 - Jun 30, 2015
    Role: Principal Investigator
    Stochastic Pulsing in Microbial Regulation and Differentiation
    NIH R01GM079771Feb 1, 2007 - Jun 30, 2017
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Diversity in Notch ligand-receptor signaling interactions. Elife. 2025 Jan 03; 12. Kuintzle R, Santat LA, Elowitz MB. PMID: 39751380; PMCID: PMC11698495.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    2. A synthetic protein-level neural network in mammalian cells. Science. 2024 Dec 13; 386(6727):1243-1250. Chen Z, Linton JM, Xia S, Fan X, Yu D, Wang J, Zhu R, Elowitz MB. PMID: 39666795.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. The lives of cells, recorded. Nat Rev Genet. 2024 Nov 25. Askary A, Chen W, Choi J, Du LY, Elowitz MB, Gagnon JA, Schier AF, Seidel S, Shendure J, Stadler T, Tran M. PMID: 39587306.
      View in: PubMed   Mentions:    Fields:    
    4. Simultaneous Protein and RNA Analysis in Single Extracellular Vesicles, Including Viruses. ACS Nano. 2024 Oct 01; 18(39):26568-26584. Troyer Z, Gololobova O, Koppula A, Liao Z, Horns F, Elowitz MB, Tosar JP, Batish M, Witwer KW. PMID: 39306763; PMCID: PMC11447916.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Temporal BMP4 effects on mouse embryonic and extraembryonic development. Nature. 2024 Oct; 634(8034):652-661. Hadas R, Rubinstein H, Mittnenzweig M, Mayshar Y, Ben-Yair R, Cheng S, Aguilera-Castrejon A, Reines N, Orenbuch AH, Lifshitz A, Chen DY, Elowitz MB, Zernicka-Goetz M, Hanna JH, Tanay A, Stelzer Y. PMID: 39294373; PMCID: PMC11485214.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. Principles of Computation by Competitive Protein Dimerization Networks. bioRxiv. 2024 Sep 15. Parres-Gold J, Levine M, Emert B, Stuart A, Elowitz MB. PMID: 37961250; PMCID: PMC10634983.
      View in: PubMed   Mentions:
    7. Diversity in Notch ligand-receptor signaling interactions. bioRxiv. 2024 Jul 31. Kuintzle R, Santat LA, Elowitz MB. PMID: 37662208; PMCID: PMC10473737.
      View in: PubMed   Mentions:
    8. Synthetic protein circuits for programmable control of mammalian cell death. Cell. 2024 May 23; 187(11):2785-2800.e16. Xia S, Lu AC, Tobin V, Luo K, Moeller L, Shon DJ, Du R, Linton JM, Sui M, Horns F, Elowitz MB. PMID: 38657604; PMCID: PMC11127782.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Synthetic dosage-compensating miRNA circuits allow precision gene therapy for Rett syndrome. bioRxiv. 2024 Mar 14. Flynn MJ, Mayfield AMH, Du R, Gradinaru V, Elowitz MB. PMID: 38559034; PMCID: PMC10980028.
      View in: PubMed   Mentions:
    10. miRNA circuit modules for precise, tunable control of gene expression. bioRxiv. 2024 Mar 12. Du R, Flynn MJ, Honsa M, Jungmann R, Elowitz MB. PMID: 38559239; PMCID: PMC10979901.
      View in: PubMed   Mentions:
    11. Lineage motifs as developmental modules for control of cell type proportions. Dev Cell. 2024 Mar 25; 59(6):812-826.e3. Tran M, Askary A, Elowitz MB. PMID: 38359830.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    12. Combinatorial expression motifs in signaling pathways. Cell Genom. 2024 Jan 10; 4(1):100463. Granados AA, Kanrar N, Elowitz MB. PMID: 38216284; PMCID: PMC10794782.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    13. Tuning Methylation-Dependent Silencing Dynamics by Synthetic Modulation of CpG Density. ACS Synth Biol. 2023 09 15; 12(9):2536-2545. Ma Y, Budde MW, Zhu J, Elowitz MB. PMID: 37572041; PMCID: PMC10510725.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. Reconstitution of morphogen shuttling circuits. Sci Adv. 2023 07 14; 9(28):eadf9336. Zhu R, Santat LA, Markson JS, Nandagopal N, Gregrowicz J, Elowitz MB. PMID: 37436981; PMCID: PMC10337948.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    15. Engineering RNA export for measurement and manipulation of living cells. Cell. 2023 08 17; 186(17):3642-3658.e32. Horns F, Martinez JA, Fan C, Haque M, Linton JM, Tobin V, Santat L, Maggiolo AO, Bjorkman PJ, Lois C, Elowitz MB. PMID: 37437570; PMCID: PMC10528933.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    16. The computational capabilities of many-to-many protein interaction networks. Cell Syst. 2023 06 21; 14(6):430-446. Klumpe HE, Garcia-Ojalvo J, Elowitz MB, Antebi YE. PMID: 37348461; PMCID: PMC10318606.
      View in: PubMed   Mentions: 5     Fields:    
    17. Lineage motifs: developmental modules for control of cell type proportions. bioRxiv. 2023 Jun 07. Tran M, Askary A, Elowitz MB. PMID: 37333085; PMCID: PMC10274800.
      View in: PubMed   Mentions:
    18. Tuning methylation-dependent silencing dynamics by synthetic modulation of CpG density. bioRxiv. 2023 Jun 01. Ma Y, Budde MW, Zhu J, Elowitz MB. PMID: 37398290; PMCID: PMC10312471.
      View in: PubMed   Mentions:
    19. Alternative splicing of GSDMB modulates killer lymphocyte-triggered pyroptosis. Sci Immunol. 2023 04 28; 8(82):eadg3196. Kong Q, Xia S, Pan X, Ye K, Li Z, Li H, Tang X, Sahni N, Yi SS, Liu X, Wu H, Elowitz MB, Lieberman J, Zhang Z. PMID: 37115914; PMCID: PMC10338320.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    20. The sound of silence: Transgene silencing in mammalian cell engineering. Cell Syst. 2022 12 21; 13(12):950-973. Cabrera A, Edelstein HI, Glykofrydis F, Love KS, Palacios S, Tycko J, Zhang M, Lensch S, Shields CE, Livingston M, Weiss R, Zhao H, Haynes KA, Morsut L, Chen YY, Khalil AS, Wong WW, Collins JJ, Rosser SJ, Polizzi K, Elowitz MB, Fussenegger M, Hilton IB, Leonard JN, Bintu L, Galloway KE, Deans TL. PMID: 36549273; PMCID: PMC9880859.
      View in: PubMed   Mentions: 32     Fields:    Translation:Animals
    21. Periodic spatial patterning with a single morphogen. Cell Syst. 2022 12 21; 13(12):1033-1047.e7. Wang S, Garcia-Ojalvo J, Elowitz MB. PMID: 36435178.
      View in: PubMed   Mentions: 4     Fields:    
    22. Embryo model completes gastrulation to neurulation and organogenesis. Nature. 2022 10; 610(7930):143-153. Amadei G, Handford CE, Qiu C, De Jonghe J, Greenfeld H, Tran M, Martin BK, Chen DY, Aguilera-Castrejon A, Hanna JH, Elowitz MB, Hollfelder F, Shendure J, Glover DM, Zernicka-Goetz M. PMID: 36007540; PMCID: PMC9534772.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    23. Dynamics and functional roles of splicing factor autoregulation. Cell Rep. 2022 06 21; 39(12):110985. Ding F, Su CJ, Edmonds KK, Liang G, Elowitz MB. PMID: 35732114; PMCID: PMC9262138.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    24. The context-dependent, combinatorial logic of BMP signaling. Cell Syst. 2022 05 18; 13(5):388-407.e10. Klumpe HE, Langley MA, Linton JM, Su CJ, Antebi YE, Elowitz MB. PMID: 35421361; PMCID: PMC9127470.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    25. Ligand-receptor promiscuity enables cellular addressing. Cell Syst. 2022 05 18; 13(5):408-425.e12. Su CJ, Murugan A, Linton JM, Yeluri A, Bois J, Klumpe H, Langley MA, Antebi YE, Elowitz MB. PMID: 35421362; PMCID: PMC10897978.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    26. Synthetic mammalian signaling circuits for robust cell population control. Cell. 2022 03 17; 185(6):967-979.e12. Ma Y, Budde MW, Mayalu MN, Zhu J, Lu AC, Murray RM, Elowitz MB. PMID: 35235768; PMCID: PMC8995209.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    27. Protease-controlled secretion and display of intercellular signals. Nat Commun. 2022 02 17; 13(1):912. Vlahos AE, Kang J, Aldrete CA, Zhu R, Chong LS, Elowitz MB, Gao XJ. PMID: 35177637; PMCID: PMC8854555.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    28. Synthetic multistability in mammalian cells. Science. 2022 01 21; 375(6578):eabg9765. Zhu R, Del Rio-Salgado JM, Garcia-Ojalvo J, Elowitz MB. PMID: 35050677.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    29. Single cell biology-a Keystone Symposia report. Ann N Y Acad Sci. 2021 12; 1506(1):74-97. Cable J, Elowitz MB, Domingos AI, Habib N, Itzkovitz S, Hamidzada H, Balzer MS, Yanai I, Liberali P, Whited J, Streets A, Cai L, Stergachis AB, Hong CKY, Keren L, Guilliams M, Alon U, Shalek AK, Hamel R, Pfau SJ, Raj A, Quake SR, Zhang NR, Fan J, Trapnell C, Wang B, Greenwald NF, Vento-Tormo R, Santos SDM, Spencer SL, Garcia HG, Arekatla G, Gaiti F, Arbel-Goren R, Rulands S, Junker JP, Klein AM, Morris SA, Murray JI, Galloway KE, Ratz M, Romeike M. PMID: 34605044.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    30. Benchmarked approaches for reconstruction of in vitro cell lineages and in silico models of C. elegans and M. musculus developmental trees. Cell Syst. 2021 08 18; 12(8):810-826.e4. Gong W, Granados AA, Hu J, Jones MG, Raz O, Salvador-Martínez I, Zhang H, Chow KK, Kwak IY, Retkute R, Prusokiene A, Prusokas A, Khodaverdian A, Zhang R, Rao S, Wang R, Rennert P, Saipradeep VG, Sivadasan N, Rao A, Joseph T, Srinivasan R, Peng J, Han L, Shang X, Garry DJ, Yu T, Chung V, Mason M, Liu Z, Guan Y, Yosef N, Shendure J, Telford MJ, Shapiro E, Elowitz MB, Meyer P. PMID: 34146472.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    31. Programmable protein circuit design. Cell. 2021 04 29; 184(9):2284-2301. Chen Z, Elowitz MB. PMID: 33848464; PMCID: PMC8087657.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimals
    32. Imaging cell lineage with a synthetic digital recording system. Science. 2021 04 09; 372(6538). Chow KK, Budde MW, Granados AA, Cabrera M, Yoon S, Cho S, Huang TH, Koulena N, Frieda KL, Cai L, Lois C, Elowitz MB. PMID: 33833095.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    33. Publisher Correction: In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription. Nat Biotechnol. 2020 Feb; 38(2):245. Askary A, Sanchez-Guardado L, Linton JM, Chadly DM, Budde MW, Cai L, Lois C, Elowitz MB. PMID: 31988471.
      View in: PubMed   Mentions: 1     Fields:    
    34. In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription. Nat Biotechnol. 2020 01; 38(1):66-75. Askary A, Sanchez-Guardado L, Linton JM, Chadly DM, Budde MW, Cai L, Lois C, Elowitz MB. PMID: 31740838; PMCID: PMC6954335.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    35. Communication codes in developmental signaling pathways. Development. 2019 06 27; 146(12). Li P, Elowitz MB. PMID: 31249008; PMCID: PMC6602343.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    36. Constitutive splicing and economies of scale in gene expression. Nat Struct Mol Biol. 2019 06; 26(6):424-432. Ding F, Elowitz MB. PMID: 31133700; PMCID: PMC6663491.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    37. Cis-activation in the Notch signaling pathway. Elife. 2019 01 10; 8. Nandagopal N, Santat LA, Elowitz MB. PMID: 30628888; PMCID: PMC6345567.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    38. A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment. Elife. 2018 11 20; 7. Ng KK, Yui MA, Mehta A, Siu S, Irwin B, Pease S, Hirose S, Elowitz MB, Rothenberg EV, Kueh HY. PMID: 30457103; PMCID: PMC6245732.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    39. Self-Amplifying Pulsatile Protein Dynamics without Positive Feedback. Cell Syst. 2018 10 24; 7(4):453-462.e1. Martinez-Corral R, Raimundez E, Lin Y, Elowitz MB, Garcia-Ojalvo J. PMID: 30316816.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    40. Programmable protein circuits in living cells. Science. 2018 09 21; 361(6408):1252-1258. Gao XJ, Chong LS, Kim MS, Elowitz MB. PMID: 30237357; PMCID: PMC7176481.
      View in: PubMed   Mentions: 138     Fields:    Translation:Cells
    41. Metabolic interactions between dynamic bacterial subpopulations. Elife. 2018 05 29; 7. Rosenthal AZ, Qi Y, Hormoz S, Park J, Li SH, Elowitz MB. PMID: 29809139; PMCID: PMC6025961.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    42. Morphogen gradient reconstitution reveals Hedgehog pathway design principles. Science. 2018 05 04; 360(6388):543-548. Li P, Markson JS, Wang S, Chen S, Vachharajani V, Elowitz MB. PMID: 29622726; PMCID: PMC6516753.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    43. Molecular Time Sharing through Dynamic Pulsing in Single Cells. Cell Syst. 2018 Feb 28; 6(2):216-229.e15. Park J, Dies M, Lin Y, Hormoz S, Smith-Unna SE, Quinodoz S, Hernández-Jiménez MJ, Garcia-Ojalvo J, Locke JCW, Elowitz MB. PMID: 29454936; PMCID: PMC6070344.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    44. Dynamic Ligand Discrimination in the Notch Signaling Pathway. Cell. 2018 02 08; 172(4):869-880.e19. Nandagopal N, Santat LA, LeBon L, Sprinzak D, Bronner ME, Elowitz MB. PMID: 29398116; PMCID: PMC6414217.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansAnimalsCells
    45. Combinatorial Signal Perception in the BMP Pathway. Cell. 2017 Sep 07; 170(6):1184-1196.e24. Antebi YE, Linton JM, Klumpe H, Bintu B, Gong M, Su C, McCardell R, Elowitz MB. PMID: 28886385; PMCID: PMC5612783.
      View in: PubMed   Mentions: 112     Fields:    Translation:AnimalsCells
    46. Challenges and emerging directions in single-cell analysis. Genome Biol. 2017 05 08; 18(1):84. Yuan GC, Cai L, Elowitz M, Enver T, Fan G, Guo G, Irizarry R, Kharchenko P, Kim J, Orkin S, Quackenbush J, Saadatpour A, Schroeder T, Shivdasani R, Tirosh I. PMID: 28482897; PMCID: PMC5421338.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansAnimals
    47. An operational view of intercellular signaling pathways. Curr Opin Syst Biol. 2017 Feb; 1:16-24. Antebi YE, Nandagopal N, Elowitz MB. PMID: 29104946; PMCID: PMC5665397.
      View in: PubMed   Mentions: 27  
    48. Inferring Cell-State Transition Dynamics from Lineage Trees and Endpoint Single-Cell Measurements. Cell Syst. 2016 11 23; 3(5):419-433.e8. Hormoz S, Singer ZS, Linton JM, Antebi YE, Shraiman BI, Elowitz MB. PMID: 27883889; PMCID: PMC5142829.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    49. Synthetic recording and in situ readout of lineage information in single cells. Nature. 2017 01 05; 541(7635):107-111. Frieda KL, Linton JM, Hormoz S, Choi J, Chow KK, Singer ZS, Budde MW, Elowitz MB, Cai L. PMID: 27869821; PMCID: PMC6487260.
      View in: PubMed   Mentions: 179     Fields:    Translation:AnimalsCells
    50. Synthetic biology: Precision timing in a cell. Nature. 2016 10 27; 538(7626):462-463. Gao XJ, Elowitz MB. PMID: 27732579.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment. Nat Immunol. 2016 08; 17(8):956-65. Kueh HY, Yui MA, Ng KK, Pease SS, Zhang JA, Damle SS, Freedman G, Siu S, Bernstein ID, Elowitz MB, Rothenberg EV. PMID: 27376470; PMCID: PMC4955789.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    52. Central Dogma Goes Digital. Mol Cell. 2016 Mar 17; 61(6):791-2. Lin Y, Elowitz MB. PMID: 26990983.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    53. Dynamics of epigenetic regulation at the single-cell level. Science. 2016 Feb 12; 351(6274):720-4. Bintu L, Yong J, Antebi YE, McCue K, Kazuki Y, Uno N, Oshimura M, Elowitz MB. PMID: 26912859; PMCID: PMC5108652.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansAnimalsCells
    54. Combinatorial gene regulation by modulation of relative pulse timing. Nature. 2015 Nov 05; 527(7576):54-8. Lin Y, Sohn CH, Dalal CK, Cai L, Elowitz MB. PMID: 26466562; PMCID: PMC4870307.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    55. Single-cell transcriptome analysis reveals dynamic changes in lncRNA expression during reprogramming. Cell Stem Cell. 2015 Jan 08; 16(1):88-101. Kim DH, Marinov GK, Pepke S, Singer ZS, He P, Williams B, Schroth GP, Elowitz MB, Wold BJ. PMID: 25575081; PMCID: PMC4291542.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    56. Synthetic biology of multicellular systems: new platforms and applications for animal cells and organisms. ACS Synth Biol. 2014 Dec 19; 3(12):875-6. Markson JS, Elowitz MB. PMID: 25524091; PMCID: PMC4476972.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    57. Polyphasic feedback enables tunable cellular timers. Curr Biol. 2014 Oct 20; 24(20):R994-5. Levine JH, Elowitz MB. PMID: 25442853; PMCID: PMC4451454.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    58. Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states. Elife. 2014 Sep 25; 3:e02950. LeBon L, Lee TV, Sprinzak D, Jafar-Nejad H, Elowitz MB. PMID: 25255098; PMCID: PMC4174579.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    59. Pulsatile dynamics in the yeast proteome. Curr Biol. 2014 Sep 22; 24(18):2189-2194. Dalal CK, Cai L, Lin Y, Rahbar K, Elowitz MB. PMID: 25220054; PMCID: PMC4203654.
      View in: PubMed   Mentions: 46     Fields:    Translation:Animals
    60. Dynamic heterogeneity and DNA methylation in embryonic stem cells. Mol Cell. 2014 Jul 17; 55(2):319-31. Singer ZS, Yong J, Tischler J, Hackett JA, Altinok A, Surani MA, Cai L, Elowitz MB. PMID: 25038413; PMCID: PMC4104113.
      View in: PubMed   Mentions: 160     Fields:    Translation:AnimalsCells
    61. Brf1 posttranscriptionally regulates pluripotency and differentiation responses downstream of Erk MAP kinase. Proc Natl Acad Sci U S A. 2014 Apr 29; 111(17):E1740-8. Tan FE, Elowitz MB. PMID: 24733888; PMCID: PMC4035916.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    62. Realizing the potential of synthetic biology. Nat Rev Mol Cell Biol. 2014 04; 15(4):289-94. Church GM, Elowitz MB, Smolke CD, Voigt CA, Weiss R. PMID: 24622617; PMCID: PMC9645560.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    63. Functional roles of pulsing in genetic circuits. Science. 2013 Dec 06; 342(6163):1193-200. Levine JH, Lin Y, Elowitz MB. PMID: 24311681; PMCID: PMC4100686.
      View in: PubMed   Mentions: 193     Fields:    Translation:AnimalsCells
    64. Positive feedback between PU.1 and the cell cycle controls myeloid differentiation. Science. 2013 Aug 09; 341(6146):670-3. Kueh HY, Champhekar A, Champhekhar A, Nutt SL, Elowitz MB, Rothenberg EV. PMID: 23868921; PMCID: PMC3913367.
      View in: PubMed   Mentions: 155     Fields:    Translation:AnimalsCells
    65. Rate of environmental change determines stress response specificity. Proc Natl Acad Sci U S A. 2013 Mar 05; 110(10):4140-5. Young JW, Locke JC, Elowitz MB. PMID: 23407164; PMCID: PMC3593889.
      View in: PubMed   Mentions: 67     Fields:    Translation:Cells
    66. Pulsed feedback defers cellular differentiation. PLoS Biol. 2012 Jan; 10(1):e1001252. Levine JH, Fontes ME, Dworkin J, Elowitz MB. PMID: 22303282; PMCID: PMC3269414.
      View in: PubMed   Mentions: 64     Fields:    Translation:Cells
    67. Following evolution of bacterial antibiotic resistance in real time. Nat Genet. 2011 Dec 27; 44(1):11-3. Rosenthal AZ, Elowitz MB. PMID: 22200772.
      View in: PubMed   Mentions: 3     Fields:    
    68. Measuring single-cell gene expression dynamics in bacteria using fluorescence time-lapse microscopy. Nat Protoc. 2011 Dec 15; 7(1):80-8. Young JW, Locke JC, Altinok A, Rosenfeld N, Bacarian T, Swain PS, Mjolsness E, Elowitz MB. PMID: 22179594; PMCID: PMC4161363.
      View in: PubMed   Mentions: 161     Fields:    Translation:Cells
    69. Stochastic pulse regulation in bacterial stress response. Science. 2011 Oct 21; 334(6054):366-9. Locke JC, Young JW, Fontes M, Hernández Jiménez MJ, Elowitz MB. PMID: 21979936; PMCID: PMC4100694.
      View in: PubMed   Mentions: 113     Fields:    Translation:Cells
    70. The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM). Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):16889-94. Zheng G, Lee SA, Antebi Y, Elowitz MB, Yang C. PMID: 21969539; PMCID: PMC3193234.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    71. Dynamical consequences of bandpass feedback loops in a bacterial phosphorelay. PLoS One. 2011; 6(9):e25102. Sen S, Garcia-Ojalvo J, Elowitz MB. PMID: 21980382; PMCID: PMC3182994.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    72. Synthetic biology: integrated gene circuits. Science. 2011 Sep 02; 333(6047):1244-8. Nandagopal N, Elowitz MB. PMID: 21885772; PMCID: PMC4117316.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    73. Mutual inactivation of Notch receptors and ligands facilitates developmental patterning. PLoS Comput Biol. 2011 Jun; 7(6):e1002069. Sprinzak D, Lakhanpal A, LeBon L, Garcia-Ojalvo J, Elowitz MB. PMID: 21695234; PMCID: PMC3111533.
      View in: PubMed   Mentions: 56     Fields:    Translation:Animals
    74. Mixed messages: how bacteria resolve conflicting signals. Mol Cell. 2011 May 20; 42(4):405-6. Young JW, Elowitz MB. PMID: 21596304; PMCID: PMC4117311.
      View in: PubMed   Mentions: 1     Fields:    
    75. Build life to understand it. Nature. 2010 Dec 16; 468(7326):889-90. Elowitz M, Lim WA. PMID: 21164460; PMCID: PMC3068207.
      View in: PubMed   Mentions: 75     Fields:    Translation:Animals
    76. A general mechanism for network-dosage compensation in gene circuits. Science. 2010 Sep 24; 329(5999):1656-60. Acar M, Pando BF, Arnold FH, Elowitz MB, van Oudenaarden A. PMID: 20929850; PMCID: PMC3138731.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    77. Functional roles for noise in genetic circuits. Nature. 2010 Sep 09; 467(7312):167-73. Eldar A, Elowitz MB. PMID: 20829787; PMCID: PMC4100692.
      View in: PubMed   Mentions: 604     Fields:    Translation:HumansAnimals
    78. A synthetic three-color scaffold for monitoring genetic regulation and noise. J Biol Eng. 2010 Jul 21; 4:10. Cox RS, Dunlop MJ, Elowitz MB. PMID: 20646328; PMCID: PMC2918530.
      View in: PubMed   Mentions: 37  
    79. Cis-interactions between Notch and Delta generate mutually exclusive signalling states. Nature. 2010 May 06; 465(7294):86-90. Sprinzak D, Lakhanpal A, Lebon L, Santat LA, Fontes ME, Anderson GA, Garcia-Ojalvo J, Elowitz MB. PMID: 20418862; PMCID: PMC2886601.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansAnimalsCells
    80. Architecture-dependent noise discriminates functionally analogous differentiation circuits. Cell. 2009 Oct 30; 139(3):512-22. Cagatay T, Turcotte M, Elowitz MB, Garcia-Ojalvo J, Süel GM. PMID: 19853288.
      View in: PubMed   Mentions: 113     Fields:    Translation:Cells
    81. Partial penetrance facilitates developmental evolution in bacteria. Nature. 2009 Jul 23; 460(7254):510-4. Eldar A, Chary VK, Xenopoulos P, Fontes ME, Losón OC, Dworkin J, Piggot PJ, Elowitz MB. PMID: 19578359; PMCID: PMC2716064.
      View in: PubMed   Mentions: 64     Fields:    Translation:Cells
    82. Using movies to analyse gene circuit dynamics in single cells. Nat Rev Microbiol. 2009 May; 7(5):383-92. Locke JC, Elowitz MB. PMID: 19369953; PMCID: PMC2853934.
      View in: PubMed   Mentions: 111     Fields:    Translation:Cells
    83. Regulatory activity revealed by dynamic correlations in gene expression noise. Nat Genet. 2008 Dec; 40(12):1493-8. Dunlop MJ, Cox RS, Levine JH, Murray RM, Elowitz MB. PMID: 19029898; PMCID: PMC2829635.
      View in: PubMed   Mentions: 113     Fields:    Translation:Cells
    84. Frequency-modulated nuclear localization bursts coordinate gene regulation. Nature. 2008 Sep 25; 455(7212):485-90. Cai L, Dalal CK, Elowitz MB. PMID: 18818649; PMCID: PMC2695983.
      View in: PubMed   Mentions: 243     Fields:    Translation:AnimalsCells
    85. The evolutionary dynamics of the Saccharomyces cerevisiae protein interaction network after duplication. Proc Natl Acad Sci U S A. 2008 Jan 22; 105(3):950-4. Presser A, Elowitz MB, Kellis M, Kishony R. PMID: 18199840; PMCID: PMC2242688.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    86. Accurate prediction of gene feedback circuit behavior from component properties. Mol Syst Biol. 2007; 3:143. Rosenfeld N, Young JW, Alon U, Swain PS, Elowitz MB. PMID: 18004276; PMCID: PMC2132446.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    87. Programming gene expression with combinatorial promoters. Mol Syst Biol. 2007; 3:145. Cox RS, Surette MG, Elowitz MB. PMID: 18004278; PMCID: PMC2132448.
      View in: PubMed   Mentions: 165     Fields:    Translation:Cells
    88. Tunability and noise dependence in differentiation dynamics. Science. 2007 Mar 23; 315(5819):1716-9. Süel GM, Kulkarni RP, Dworkin J, Garcia-Ojalvo J, Elowitz MB. PMID: 17379809.
      View in: PubMed   Mentions: 216     Fields:    Translation:Cells
    89. A fluctuation method to quantify in vivo fluorescence data. Biophys J. 2006 Jul 15; 91(2):759-66. Rosenfeld N, Perkins TJ, Alon U, Elowitz MB, Swain PS. PMID: 16648159; PMCID: PMC1483091.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    90. An excitable gene regulatory circuit induces transient cellular differentiation. Nature. 2006 Mar 23; 440(7083):545-50. Süel GM, Garcia-Ojalvo J, Liberman LM, Elowitz MB. PMID: 16554821.
      View in: PubMed   Mentions: 288     Fields:    Translation:Cells
    91. Reconstruction of genetic circuits. Nature. 2005 Nov 24; 438(7067):443-8. Sprinzak D, Elowitz MB. PMID: 16306982.
      View in: PubMed   Mentions: 113     Fields:    Translation:Animals
    92. Systems biology: deviations in mating. Nature. 2005 Sep 29; 437(7059):631-2. Eldar A, Elowitz M. PMID: 16193031.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    93. Gene regulation at the single-cell level. Science. 2005 Mar 25; 307(5717):1962-5. Rosenfeld N, Young JW, Alon U, Swain PS, Elowitz MB. PMID: 15790856.
      View in: PubMed   Mentions: 433     Fields:    Translation:Cells
    94. Modeling a synthetic multicellular clock: repressilators coupled by quorum sensing. Proc Natl Acad Sci U S A. 2004 Jul 27; 101(30):10955-60. Garcia-Ojalvo J, Elowitz MB, Strogatz SH. PMID: 15256602; PMCID: PMC503725.
      View in: PubMed   Mentions: 113     Fields:    Translation:Cells
    95. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat Genet. 2004 Feb; 36(2):147-50. Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U. PMID: 14730303.
      View in: PubMed   Mentions: 415     Fields:    Translation:HumansCells
    96. The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11547-52. Overholtzer M, Rao PH, Favis R, Lu XY, Elowitz MB, Barany F, Ladanyi M, Gorlick R, Levine AJ. PMID: 12972634; PMCID: PMC208795.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    97. Negative autoregulation speeds the response times of transcription networks. J Mol Biol. 2002 Nov 08; 323(5):785-93. Rosenfeld N, Elowitz MB, Alon U. PMID: 12417193.
      View in: PubMed   Mentions: 280     Fields:    Translation:Cells
    98. Intrinsic and extrinsic contributions to stochasticity in gene expression. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):12795-800. Swain PS, Elowitz MB, Siggia ED. PMID: 12237400; PMCID: PMC130539.
      View in: PubMed   Mentions: 575     Fields:    Translation:Cells
    99. Stochastic gene expression in a single cell. Science. 2002 Aug 16; 297(5584):1183-6. Elowitz MB, Levine AJ, Siggia ED, Swain PS. PMID: 12183631.
      View in: PubMed   Mentions: 1994     Fields:    Translation:Cells
    100. Combinatorial synthesis of genetic networks. Science. 2002 May 24; 296(5572):1466-70. Guet CC, Elowitz MB, Hsing W, Leibler S. PMID: 12029133.
      View in: PubMed   Mentions: 169     Fields:    Translation:Cells
    101. A synthetic oscillatory network of transcriptional regulators. Nature. 2000 Jan 20; 403(6767):335-8. Elowitz MB, Leibler S. PMID: 10659856.
      View in: PubMed   Mentions: 1172     Fields:    Translation:Cells
    102. Protein mobility in the cytoplasm of Escherichia coli. J Bacteriol. 1999 Jan; 181(1):197-203. Elowitz MB, Surette MG, Wolf PE, Stock JB, Leibler S. PMID: 9864330; PMCID: PMC103549.
      View in: PubMed   Mentions: 245     Fields:    Translation:Cells
    103. Chromophore-assisted light inactivation and self-organization of microtubules and motors. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4293-8. Surrey T, Elowitz MB, Wolf PE, Yang F, Nédélec F, Shokat K, Leibler S. PMID: 9539730; PMCID: PMC22482.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    104. Photoactivation turns green fluorescent protein red. Curr Biol. 1997 Oct 01; 7(10):809-12. Elowitz MB, Surette MG, Wolf PE, Stock J, Leibler S. PMID: 9368766.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
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