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Chen, Yvonne Yu-Hsuan

Title(s)Associate Professor, Mimg
Phone310-825-2816
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    Collapse Research 
    Collapse Research Activities and Funding
    Engineering of computational receptors and gene circuits for T-cell immunotherapy
    NIH DP5OD012133Sep 25, 2012 - Aug 31, 2017
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chang ZL, Hou AJ, Chen YY. Engineering primary T cells with chimeric antigen receptors for rewired responses to soluble ligands. Nat Protoc. 2020 Feb 26. PMID: 32103205.
      View in: PubMed
    2. Chen YY, Van Deventer JA. Editorial overview: Pharmaceutical biotechnology: new frontiers in protein, gene, and cell therapies. Curr Opin Biotechnol. 2019 12; 60:iii-v. PMID: 31690473.
      View in: PubMed
    3. Chen YY. Cell fishing with DNA aptamers. Nat Biomed Eng. 2019 10; 3(10):757-758. PMID: 31591522.
      View in: PubMed
    4. Chen LC, Chen YY. Outsmarting and outmuscling cancer cells with synthetic and systems immunology. Curr Opin Biotechnol. 2019 12; 60:111-118. PMID: 30822698.
      View in: PubMed
    5. Hou AJ, Chang ZL, Lorenzini MH, Zah E, Chen YY. TGF-ß-responsive CAR-T cells promote anti-tumor immune function. Bioeng Transl Med. 2018 May; 3(2):75-86. PMID: 30065964.
      View in: PubMed
    6. Chen YY. Increasing T Cell Versatility with SUPRA CARs. Cell. 2018 05 31; 173(6):1316-1317. PMID: 29856949.
      View in: PubMed
    7. Chang ZL, Lorenzini MH, Chen X, Tran U, Bangayan NJ, Chen YY. Rewiring T-cell responses to soluble factors with chimeric antigen receptors. Nat Chem Biol. 2018 03; 14(3):317-324. PMID: 29377003.
      View in: PubMed
    8. Ho P, Chen YY. Mammalian synthetic biology in the age of genome editing and personalized medicine. Curr Opin Chem Biol. 2017 Oct; 40:57-64. PMID: 28628856.
      View in: PubMed
    9. Ho P, Ede C, Chen YY. Modularly Constructed Synthetic Granzyme B Molecule Enables Interrogation of Intracellular Proteases for Targeted Cytotoxicity. ACS Synth Biol. 2017 08 18; 6(8):1484-1495. PMID: 28510446.
      View in: PubMed
    10. Chang ZL, Chen YY. CARs: Synthetic Immunoreceptors for Cancer Therapy and Beyond. Trends Mol Med. 2017 05; 23(5):430-450. PMID: 28416139.
      View in: PubMed
    11. Zah E, Lin MY, Silva-Benedict A, Jensen MC, Chen YY. T Cells Expressing CD19/CD20 Bispecific Chimeric Antigen Receptors Prevent Antigen Escape by Malignant B Cells. Cancer Immunol Res. 2016 06; 4(6):498-508. PMID: 27059623.
      View in: PubMed
    12. Ede C, Chen X, Lin MY, Chen YY. Quantitative Analyses of Core Promoters Enable Precise Engineering of Regulated Gene Expression in Mammalian Cells. ACS Synth Biol. 2016 05 20; 5(5):395-404. PMID: 26883397.
      View in: PubMed
    13. Chen YY. Efficient Gene Editing in Primary Human T Cells. Trends Immunol. 2015 Nov; 36(11):667-669. PMID: 26440702.
      View in: PubMed
    14. Chang ZL, Silver PA, Chen YY. Identification and selective expansion of functionally superior T cells expressing chimeric antigen receptors. J Transl Med. 2015 May 20; 13:161. PMID: 25990251.
      View in: PubMed