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Skeletal muscle-on-a-chip in microgravity as a platform for regeneration modeling and drug screening. Stem Cell Reports. 2024 Aug 13; 19(8):1061-1073.
Kim S, Ayan B, Shayan M, Rando TA, Huang NF. PMID: 39059375; PMCID: PMC11368695.
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PubMed Mentions: Fields:
Translation:
Humans
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Spatiotemporal transcriptomic profiling and modeling of mouse brain at single-cell resolution reveals cell proximity effects of aging and rejuvenation. bioRxiv. 2024 Jul 19.
Sun ED, Zhou OY, Hauptschein M, Rappoport N, Xu L, Navarro Negredo P, Liu L, Rando TA, Zou J, Brunet A. PMID: 39071282; PMCID: PMC11275735.
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Erratum: Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation. iScience. 2024 Jul 19; 27(7):110313.
Reyes JM, Tovy A, Zhang L, Bortoletto AS, Rosas C, Chen CW, Waldvogel SM, Guzman AG, Aguilar R, Gupta S, Liu L, Buckley MT, Patel KR, Marcogliese AN, Li Y, Curry CV, Rando TA, Brunet A, Parchem RJ, Rau RE, Goodell MA. PMID: 39027369; PMCID: PMC11255835.
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PubMed Mentions:
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Scanorama: integrating large and diverse single-cell transcriptomic datasets. Nat Protoc. 2024 Aug; 19(8):2283-2297.
Hie BL, Kim S, Rando TA, Bryson B, Berger B. PMID: 38844552; PMCID: PMC11361826.
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Translation:
HumansCells
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Division-Independent Differentiation of Muscle Stem Cells During a Growth Stimulus. Stem Cells. 2024 Mar 14; 42(3):266-277.
Ismaeel A, Goh J, Mobley CB, Murach KA, Brett JO, de Morrée A, Rando TA, Peterson CA, Wen Y, McCarthy JJ. PMID: 38066665; PMCID: PMC10938546.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation. iScience. 2024 Mar 15; 27(3):109122.
Reyes JM, Tovy A, Zhang L, Bortoletto AS, Rosas C, Chen CW, Waldvogel SM, Guzman AG, Aguilar R, Gupta S, Liu L, Buckley MT, Patel KR, Marcogliese AN, Li Y, Curry CV, Rando TA, Brunet A, Parchem RJ, Rau RE, Goodell MA. PMID: 38414863; PMCID: PMC10897855.
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PubMed Mentions:
2
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Depletion of SAM leading to loss of heterochromatin drives muscle stem cell ageing. Nat Metab. 2024 Jan; 6(1):153-168.
Kang J, Benjamin DI, Kim S, Salvi JS, Dhaliwal G, Lam R, Goshayeshi A, Brett JO, Liu L, Rando TA. PMID: 38243132; PMCID: PMC10976122.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Expression of Concern: The bi-directional translocation of MARCKS between membrane and cytosol regulates integrin-mediated muscle cell spreading. J Cell Sci. 2023 11 15; 136(22).
Disatnik MH, Boutet SC, Pacio W, Chan AY, Ross LB, Lee CH, Rando TA. PMID: 37997931.
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Expression of Concern: Sequential activation of individual PKC isozymes in integrin-mediated muscle cell spreading: a role for MARCKS in an integrin signaling pathway. J Cell Sci. 2023 11 15; 136(22).
Disatnik MH, Boutet SC, Lee CH, Mochly-Rosen D, Rando TA. PMID: 37997930.
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PubMed Mentions: Fields:
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Combinatorial activation of the WNT-dependent fibrogenic program by distinct complement subunits in dystrophic muscle. EMBO Mol Med. 2023 Dec 07; 15(12):e17405.
Florio F, Vencato S, Papa FT, Libergoli M, Kheir E, Ghzaiel I, Rando TA, Torrente Y, Biressi S. PMID: 37927228; PMCID: PMC10701616.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Death-seq identifies regulators of cell death and senolytic therapies. Cell Metab. 2023 10 03; 35(10):1814-1829.e6.
Colville A, Liu JY, Rodriguez-Mateo C, Thomas S, Ishak HD, Zhou R, Klein JDD, Morgens DW, Goshayeshi A, Salvi JS, Yao D, Spees K, Dixon SJ, Liu C, Rhee JW, Lai C, Wu JC, Bassik MC, Rando TA. PMID: 37699398; PMCID: PMC10597643.
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PubMed Mentions:
2 Fields:
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Identification of an adipose tissue-resident pro-preadipocyte population. Cell Rep. 2023 05 30; 42(5):112440.
Chen M, Kim S, Li L, Chattopadhyay S, Rando TA, Feldman BJ. PMID: 37119138; PMCID: PMC10370484.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging. Cell Stem Cell. 2023 05 04; 30(5):689-705.e4.
Liu L, Kim S, Buckley MT, Reyes JM, Kang J, Tian L, Wang M, Lieu A, Mao M, Rodriguez-Mateo C, Ishak HD, Jeong M, Wu JC, Goodell MA, Brunet A, Rando TA. PMID: 37080206; PMCID: PMC10216894.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity. Nat Rev Mol Cell Biol. 2023 05; 24(5):334-354.
de Morree A, Rando TA. PMID: 36922629; PMCID: PMC10725182.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Activation of β-catenin in mesenchymal progenitors leads to muscle mass loss. Dev Cell. 2023 03 27; 58(6):489-505.e7.
Kajabadi N, Low M, Jacques E, Lad H, Tung LW, Babaeijandaghi F, Gamu D, Zelada D, Wong CK, Chang C, Yi L, Wosczyna MN, Rando TA, Henríquez JP, Gibson WT, Gilbert PM, Rossi FMV. PMID: 36898377.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Multiomics reveals glutathione metabolism as a driver of bimodality during stem cell aging. Cell Metab. 2023 03 07; 35(3):472-486.e6.
Benjamin DI, Brett JO, Both P, Benjamin JS, Ishak HL, Kang J, Kim S, Chung M, Arjona M, Nutter CW, Tan JH, Krishnan AK, Dulay H, Louie SM, de Morree A, Nomura DK, Rando TA. PMID: 36854304; PMCID: PMC10015599.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain. Nat Aging. 2023 01; 3(1):121-137.
Buckley MT, Sun ED, George BM, Liu L, Schaum N, Xu L, Reyes JM, Goodell MA, Weissman IL, Wyss-Coray T, Rando TA, Brunet A. PMID: 37118510; PMCID: PMC10154228.
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PubMed Mentions:
26 Fields:
Translation:
Animals
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Modulating myoblast differentiation with RNA-based controllers. PLoS One. 2022; 17(9):e0275298.
Dykstra PB, Rando TA, Smolke CD. PMID: 36166456; PMCID: PMC9514614.
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PubMed Mentions: Fields:
Translation:
Cells
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Scalable macroporous hydrogels enhance stem cell treatment of volumetric muscle loss. Biomaterials. 2022 11; 290:121818.
Eugenis I, Wu D, Hu C, Chiang G, Huang NF, Rando TA. PMID: 36209578; PMCID: PMC10267099.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Regenerative medicine: postnatal approaches. Lancet Child Adolesc Health. 2022 09; 6(9):654-666.
Tam PKH, Wong KKY, Atala A, Giobbe GG, Booth C, Gruber PJ, Monone M, Rafii S, Rando TA, Vacanti J, Comer CD, Elvassore N, Grikscheit T, de Coppi P. PMID: 35963270.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Ageing and rejuvenation of tissue stem cells and their niches. Nat Rev Mol Cell Biol. 2023 01; 24(1):45-62.
Brunet A, Goodell MA, Rando TA. PMID: 35859206; PMCID: PMC9879573.
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PubMed Mentions:
65 Fields:
Translation:
Cells
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RNA-binding proteins direct myogenic cell fate decisions. Elife. 2022 06 13; 11.
Wheeler JR, Whitney ON, Vogler TO, Nguyen ED, Pawlikowski B, Lester E, Cutler A, Elston T, Dalla Betta N, Parker KR, Yost KE, Vogel H, Rando TA, Chang HY, Johnson AM, Parker R, Olwin BB. PMID: 35695839; PMCID: PMC9191894.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling. Cell Metab. 2022 06 07; 34(6):902-918.e6.
Benjamin DI, Both P, Benjamin JS, Nutter CW, Tan JH, Kang J, Machado LA, Klein JDD, de Morree A, Kim S, Liu L, Dulay H, Feraboli L, Louie SM, Nomura DK, Rando TA. PMID: 35584694; PMCID: PMC9177797.
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PubMed Mentions:
16 Fields:
Translation:
Cells
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The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science. 2022 05 13; 376(6594):eabl4896.
Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, Aaron KA, Concepcion W, Gardner JM, Kelly B, Neidlinger N, Wang Z, Crasta S, Kolluru S, Morri M, Tan SY, Travaglini KJ, Xu C, Alcántara-Hernández M, Almanzar N, Antony J, Beyersdorf B, Burhan D, Calcuttawala K, Carter MM, Chan CKF, Chang CA, Chang S, Colville A, Culver RN, Cvijovic I, D'Amato G, Ezran C, Galdos FX, Gillich A, Goodyer WR, Hang Y, Hayashi A, Houshdaran S, Huang X, Irwin JC, Jang S, Juanico JV, Kershner AM, Kim S, Kiss B, Kong W, Kumar ME, Kuo AH, Li B, Loeb GB, Lu WJ, Mantri S, Markovic M, McAlpine PL, de Morree A, Mrouj K, Mukherjee S, Muser T, Neuhöfer P, Nguyen TD, Perez K, Puluca N, Qi Z, Rao P, Raquer-McKay H, Schaum N, Scott B, Seddighzadeh B, Segal J, Sen S, Sikandar S, Spencer SP, Steffes LC, Subramaniam VR, Swarup A, Swift M, Van Treuren W, Trimm E, Veizades S, Vijayakumar S, Vo KC, Vorperian SK, Wang W, Weinstein HNW, Winkler J, Wu TTH, Xie J, Yung AR, Zhang Y, Detweiler AM, Mekonen H, Neff NF, Sit RV, Tan M, Yan J, Bean GR, Charu V, Forgó E, Martin BA, Ozawa MG, Silva O, Toland A, Vemuri VNP, Afik S, Awayan K, Botvinnik OB, Byrne A, Chen M, Dehghannasiri R, Gayoso A, Granados AA, Li Q, Mahmoudabadi G, McGeever A, Olivieri JE, Park M, Ravikumar N, Stanley G, Tan W, Tarashansky AJ, Vanheusden R, Wang P, Wang S, Xing G, Dethlefsen L, Ezran C, Gillich A, Hang Y, Ho PY, Irwin JC, Jang S, Leylek R, Liu S, Maltzman JS, Metzger RJ, Phansalkar R, Sasagawa K, Sinha R, Song H, Swarup A, Trimm E, Veizades S, Wang B, Beachy PA, Clarke MF, Giudice LC, Huang FW, Huang KC, Idoyaga J, Kim SK, Kuo CS, Nguyen P, Rando TA, Red-Horse K, Reiter J, Relman DA, Sonnenburg JL, Wu A, Wu SM, Wyss-Coray T. PMID: 35549404; PMCID: PMC9812260.
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PubMed Mentions:
248 Fields:
Translation:
HumansCells
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ATR activity controls stem cell quiescence via the cyclin F-SCF complex. Proc Natl Acad Sci U S A. 2022 05 03; 119(18):e2115638119.
Salvi JS, Kang J, Kim S, Colville AJ, de Morrée A, Billeskov TB, Larsen MC, Kanugovi A, van Velthoven CTJ, Cimprich KA, Rando TA. PMID: 35476521; PMCID: PMC9170012.
View in:
PubMed Mentions:
5 Fields:
Translation:
Cells
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Muscle Stem Cell Function Is Impaired in β2-Adrenoceptor Knockout Mice. Stem Cell Rev Rep. 2022 10; 18(7):2431-2443.
Koike TE, Fuziwara CS, Brum PC, Kimura ET, Rando TA, Miyabara EH. PMID: 35244862.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Comparative Effects of Basic Fibroblast Growth Factor Delivery or Voluntary Exercise on Muscle Regeneration after Volumetric Muscle Loss. Bioengineering (Basel). 2022 Jan 14; 9(1).
Hu C, Ayan B, Chiang G, Chan AHP, Rando TA, Huang NF. PMID: 35049746; PMCID: PMC8773127.
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PubMed Mentions:
7
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Tubastatin A maintains adult skeletal muscle stem cells in a quiescent state ex vivo and improves their engraftment ability in vivo. Stem Cell Reports. 2022 01 11; 17(1):82-95.
Arjona M, Goshayeshi A, Rodriguez-Mateo C, Brett JO, Both P, Ishak H, Rando TA. PMID: 35021050; PMCID: PMC8758944.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Exercise plasma boosts memory and dampens brain inflammation via clusterin. Nature. 2021 12; 600(7889):494-499.
De Miguel Z, Khoury N, Betley MJ, Lehallier B, Willoughby D, Olsson N, Yang AC, Hahn O, Lu N, Vest RT, Bonanno LN, Yerra L, Zhang L, Saw NL, Fairchild JK, Lee D, Zhang H, McAlpine PL, Contrepois K, Shamloo M, Elias JE, Rando TA, Wyss-Coray T. PMID: 34880498; PMCID: PMC9721468.
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PubMed Mentions:
121 Fields:
Translation:
HumansAnimalsCells
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Cells, scaffolds, and bioactive factors: Engineering strategies for improving regeneration following volumetric muscle loss. Biomaterials. 2021 11; 278:121173.
Eugenis I, Wu D, Rando TA. PMID: 34619561; PMCID: PMC8556323.
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PubMed Mentions:
18 Fields:
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Hairless regulates heterochromatin maintenance and muscle stem cell function as a histone demethylase antagonist. Proc Natl Acad Sci U S A. 2021 09 14; 118(37).
Liu L, Rodriguez-Mateo C, Huang P, Huang A, Lieu A, Mao M, Chung M, Yang S, Yu K, Charville GW, Gan Q, Rando TA. PMID: 34493660; PMCID: PMC8449361.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Regeneration, Rejuvenation, and Replacement: Turning Back the Clock on Tissue Aging. Cold Spring Harb Perspect Biol. 2021 09 01; 13(9).
Rando TA, Jones DL. PMID: 34187808; PMCID: PMC8411956.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms. Oncogene. 2021 08; 40(31):4955-4966.
Bauer J, Cuvelier N, Ragab N, Simon-Keller K, Nitzki F, Geyer N, Botermann DS, Elmer DP, Rosenberger A, Rando TA, Biressi S, Fagin JA, Saur D, Dullin C, Schildhaus HU, Schulz-Schaeffer W, Aberger F, Uhmann A, Hahn H. PMID: 34172934; PMCID: PMC8342309.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Electrical stimulation of human neural stem cells via conductive polymer nerve guides enhances peripheral nerve recovery. Biomaterials. 2021 08; 275:120982.
Song S, McConnell KW, Amores D, Levinson A, Vogel H, Quarta M, Rando TA, George PM. PMID: 34214785; PMCID: PMC8325644.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells. Cell Stem Cell. 2021 07 01; 28(7):1323-1334.e8.
Wosczyna MN, Perez Carbajal EE, Wagner MW, Paredes S, Konishi CT, Liu L, Wang TT, Walsh RA, Gan Q, Morrissey CS, Rando TA. PMID: 33945794; PMCID: PMC8254802.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Computational modeling of malignant ascites reveals CCL5-SDC4 interaction in the immune microenvironment of ovarian cancer. Mol Carcinog. 2021 05; 60(5):297-312.
Kim S, Han Y, Kim SI, Lee J, Jo H, Wang W, Cho U, Park WY, Rando TA, Dhanasekaran DN, Song YS. PMID: 33721368; PMCID: PMC8080545.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Asynchronous, contagious and digital aging. Nat Aging. 2021 01; 1(1):29-35.
Rando TA, Wyss-Coray T. PMID: 34223194; PMCID: PMC8248898.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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ARDD 2020: from aging mechanisms to interventions. Aging (Albany NY). 2020 12 30; 12(24):24484-24503.
Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG, Georgievskaya A, Gladyshev VN, Glass DJ, Gorbunova V, de Grey A, He WW, Hoeijmakers J, Hoffmann E, Horvath S, Houtkooper RH, Jensen MK, Jensen MB, Kane A, Kassem M, de Keizer P, Kennedy B, Karsenty G, Lamming DW, Lee KF, MacAulay N, Mamoshina P, Mellon J, Molenaars M, Moskalev A, Mund A, Niedernhofer L, Osborne B, Pak HH, Parkhitko A, Raimundo N, Rando TA, Rasmussen LJ, Reis C, Riedel CG, Franco-Romero A, Schumacher B, Sinclair DA, Suh Y, Taub PR, Toiber D, Treebak JT, Valenzano DR, Verdin E, Vijg J, Young S, Zhang L, Bakula D, Zhavoronkov A, Scheibye-Knudsen M. PMID: 33378272; PMCID: PMC7803558.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):30907-30917.
Lee SJ, Lehar A, Liu Y, Ly CH, Pham QM, Michaud M, Rydzik R, Youngstrom DW, Shen MM, Kaartinen V, Germain-Lee EL, Rando TA. PMID: 33219121; PMCID: PMC7733802.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Stem cell therapy for muscular dystrophies. J Clin Invest. 2020 11 02; 130(11):5652-5664.
Biressi S, Filareto A, Rando TA. PMID: 32946430; PMCID: PMC7598050.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Transplantation of insulin-like growth factor-1 laden scaffolds combined with exercise promotes neuroregeneration and angiogenesis in a preclinical muscle injury model. Biomater Sci. 2020 Oct 07; 8(19):5376-5389.
Alcazar CA, Hu C, Rando TA, Huang NF, Nakayama KH. PMID: 32996916; PMCID: PMC7531607.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D1. Nat Metab. 2020 04; 2(4):307-317.
Brett JO, Arjona M, Ikeda M, Quarta M, de Morrée A, Egner IM, Perandini LA, Ishak HD, Goshayeshi A, Benjamin DI, Both P, Rodríguez-Mateo C, Betley MJ, Wyss-Coray T, Rando TA. PMID: 32601609; PMCID: PMC7323974.
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PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells. Nat Commun. 2020 03 24; 11(1):1545.
Sarkar TJ, Quarta M, Mukherjee S, Colville A, Paine P, Doan L, Tran CM, Chu CR, Horvath S, Qi LS, Bhutani N, Rando TA, Sebastiano V. PMID: 32210226; PMCID: PMC7093390.
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PubMed Mentions:
103 Fields:
Translation:
HumansAnimalsCells
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Taking the Next Steps in Regenerative Rehabilitation: Establishment of a New Interdisciplinary Field. Arch Phys Med Rehabil. 2020 05; 101(5):917-923.
Willett NJ, Boninger ML, Miller LJ, Alvarez L, Aoyama T, Bedoni M, Brix KA, Chisari C, Christ G, Dearth CL, Dyson-Hudson TA, Evans CH, Goldman SM, Gregory K, Gualerzi A, Hart J, Ito A, Kuroki H, Loghmani MT, Mack DL, Malanga GA, Noble-Haeusslein L, Pasquina P, Roche JA, Rose L, Stoddart MJ, Tajino J, Terzic C, Topp KS, Wagner WR, Warden SJ, Wolf SL, Xie H, Rando TA, Ambrosio F. PMID: 32035141; PMCID: PMC7576442.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Angiotensin receptor blockade mimics the effect of exercise on recovery after orthopaedic trauma by decreasing pain and improving muscle regeneration. J Physiol. 2020 01; 598(2):317-329.
Tawfik VL, Quarta M, Paine P, Forman TE, Pajarinen J, Takemura Y, Goodman SB, Rando TA, Clark JD. PMID: 31784993; PMCID: PMC8830491.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019 12; 25(12):1822-1832.
Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, Ferrucci L, Gilroy DW, Fasano A, Miller GW, Miller AH, Mantovani A, Weyand CM, Barzilai N, Goronzy JJ, Rando TA, Effros RB, Lucia A, Kleinstreuer N, Slavich GM. PMID: 31806905; PMCID: PMC7147972.
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PubMed Mentions:
1349 Fields:
Translation:
Humans
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Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function. Science. 2019 11 08; 366(6466):734-738.
de Morree A, Klein JDD, Gan Q, Farup J, Urtasun A, Kanugovi A, Bilen B, van Velthoven CTJ, Quarta M, Rando TA. PMID: 31699935; PMCID: PMC7046176.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Adult stem cells and regenerative medicine-a symposium report. Ann N Y Acad Sci. 2020 02; 1462(1):27-36.
Cable J, Fuchs E, Weissman I, Jasper H, Glass D, Rando TA, Blau H, Debnath S, Oliva A, Park S, Passegué E, Kim C, Krasnow MA. PMID: 31655007; PMCID: PMC7135961.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle. Cell Rep. 2019 05 14; 27(7):2029-2035.e5.
Wosczyna MN, Konishi CT, Perez Carbajal EE, Wang TT, Walsh RA, Gan Q, Wagner MW, Rando TA. PMID: 31091443; PMCID: PMC7034941.
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PubMed Mentions:
145 Fields:
Translation:
AnimalsCells
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Treatment of volumetric muscle loss in mice using nanofibrillar scaffolds enhances vascular organization and integration. Commun Biol. 2019; 2:170.
Nakayama KH, Quarta M, Paine P, Alcazar C, Karakikes I, Garcia V, Abilez OJ, Calvo NS, Simmons CS, Rando TA, Huang NF. PMID: 31098403; PMCID: PMC6505043.
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PubMed Mentions:
35 Translation:
HumansAnimalsCells
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mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism. Aging Cell. 2019 06; 18(3):e12943.
Tang H, Inoki K, Brooks SV, Okazawa H, Lee M, Wang J, Kim M, Kennedy CL, Macpherson PCD, Ji X, Van Roekel S, Fraga DA, Wang K, Zhu J, Wang Y, Sharp ZD, Miller RA, Rando TA, Goldman D, Guan KL, Shrager JB. PMID: 30924297; PMCID: PMC6516169.
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PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCells
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Stem Cell Quiescence: Dynamism, Restraint, and Cellular Idling. Cell Stem Cell. 2019 02 07; 24(2):213-225.
van Velthoven CTJ, Rando TA. PMID: 30735649; PMCID: PMC6413865.
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PubMed Mentions:
118 Fields:
Translation:
HumansAnimalsCells
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Models and Studies of Aging: Executive Summary of a Report from the U13 Conference Series. J Am Geriatr Soc. 2019 03; 67(3):428-433.
Hurria A, Carpenter CR, McFarland F, Lundebjerg NE, de Cabo R, Ferrucci L, Studenski SA, Barzilai N, Briggs JP, Ix JH, Kitzman DW, Kuchel GA, Musi N, Newman JC, Rando TA, Smith AK, Walston JD, Kirkland JL, Yung R. PMID: 30693953; PMCID: PMC6403012.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Honey bee Royalactin unlocks conserved pluripotency pathway in mammals. Nat Commun. 2018 12 04; 9(1):5078.
Wan DC, Morgan SL, Spencley AL, Mariano N, Chang EY, Shankar G, Luo Y, Li TH, Huh D, Huynh SK, Garcia JM, Dovey CM, Lumb J, Liu L, Brown KV, Bermudez A, Luong R, Zeng H, Mascetti VL, Pitteri SJ, Wang J, Tu H, Quarta M, Sebastiano V, Nusse R, Rando TA, Carette JE, Bazan JF, Wang KC. PMID: 30510260; PMCID: PMC6277453.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration. Nat Commun. 2018 11 19; 9(1):4859.
Sahu A, Mamiya H, Shinde SN, Cheikhi A, Winter LL, Vo NV, Stolz D, Roginskaya V, Tang WY, St Croix C, Sanders LH, Franti M, Van Houten B, Rando TA, Barchowsky A, Ambrosio F. PMID: 30451844; PMCID: PMC6242898.
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PubMed Mentions:
74 Fields:
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AnimalsCells
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The regenerative rehabilitation collection: a forum for an emerging field. NPJ Regen Med. 2018; 3:20.
Ambrosio F, Rando TA. PMID: 30374410; PMCID: PMC6195606.
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PubMed Mentions:
3
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Biomechanics show stem cell necessity for effective treatment of volumetric muscle loss using bioengineered constructs. NPJ Regen Med. 2018; 3:18.
Quarta M, Cromie Lear MJ, Blonigan J, Paine P, Chacon R, Rando TA. PMID: 30323949; PMCID: PMC6180087.
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PubMed Mentions:
10
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Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells. Cell Stem Cell. 2018 10 04; 23(4):544-556.e4.
Liu L, Charville GW, Cheung TH, Yoo B, Santos PJ, Schroeder M, Rando TA. PMID: 30244867; PMCID: PMC6173623.
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PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
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Rehabilitative exercise and spatially patterned nanofibrillar scaffolds enhance vascularization and innervation following volumetric muscle loss. NPJ Regen Med. 2018; 3:16.
Nakayama KH, Alcazar C, Yang G, Quarta M, Paine P, Doan L, Davies A, Rando TA, Huang NF. PMID: 30245849; PMCID: PMC6141593.
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PubMed Mentions:
30
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Bioengineered Viral Platform for Intramuscular Passive Vaccine Delivery to Human Skeletal Muscle. Mol Ther Methods Clin Dev. 2018 Sep 21; 10:144-155.
Paulk NK, Pekrun K, Charville GW, Maguire-Nguyen K, Wosczyna MN, Xu J, Zhang Y, Lisowski L, Yoo B, Vilches-Moure JG, Lee GK, Shrager JB, Rando TA, Kay MA. PMID: 30101152; PMCID: PMC6077147.
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PubMed Mentions:
13
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A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration. Dev Cell. 2018 07 16; 46(2):135-143.
Wosczyna MN, Rando TA. PMID: 30016618; PMCID: PMC6075730.
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PubMed Mentions:
146 Fields:
Translation:
HumansAnimalsCells
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Monitoring disease activity noninvasively in the mdx model of Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2018 07 24; 115(30):7741-7746.
Filareto A, Maguire-Nguyen K, Gan Q, Aldanondo G, Machado L, Chamberlain JS, Rando TA. PMID: 29987034; PMCID: PMC6064991.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics. Cell Stem Cell. 2018 04 05; 22(4):608.
Rando TA, Ambrosio F. PMID: 29625074.
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5 Fields:
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Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging. Science. 2018 03 16; 359(6381):1277-1283.
Leeman DS, Hebestreit K, Ruetz T, Webb AE, McKay A, Pollina EA, Dulken BW, Zhao X, Yeo RW, Ho TT, Mahmoudi S, Devarajan K, Passegué E, Rando TA, Frydman J, Brunet A. PMID: 29590078; PMCID: PMC5915358.
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PubMed Mentions:
197 Fields:
Translation:
AnimalsCells
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Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics. Cell Stem Cell. 2018 03 01; 22(3):306-309.
Rando TA, Ambrosio F. PMID: 29499150; PMCID: PMC5931336.
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PubMed Mentions:
34 Fields:
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HumansAnimalsCells
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Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential. Cell Stem Cell. 2018 02 01; 22(2):177-190.e7.
Judson RN, Quarta M, Oudhoff MJ, Soliman H, Yi L, Chang CK, Loi G, Vander Werff R, Cait A, Hamer M, Blonigan J, Paine P, Doan LTN, Groppa E, He W, Su L, Zhang RH, Xu P, Eisner C, Low M, Barta I, Lewis CB, Zaph C, Karimi MM, Rando TA, Rossi FM. PMID: 29395054; PMCID: PMC6031334.
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27 Fields:
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AnimalsCells
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mTORC1 Activation during Repeated Regeneration Impairs Somatic Stem Cell Maintenance. Cell Stem Cell. 2017 Dec 07; 21(6):806-818.e5.
Haller S, Kapuria S, Riley RR, O'Leary MN, Schreiber KH, Andersen JK, Melov S, Que J, Rando TA, Rock J, Kennedy BK, Rodgers JT, Jasper H. PMID: 29220665; PMCID: PMC5823264.
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PubMed Mentions:
56 Fields:
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AnimalsCells
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Transcriptional Profiling of Quiescent Muscle Stem Cells In Vivo. Cell Rep. 2017 Nov 14; 21(7):1994-2004.
van Velthoven CTJ, de Morree A, Egner IM, Brett JO, Rando TA. PMID: 29141228; PMCID: PMC5711481.
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PubMed Mentions:
93 Fields:
Translation:
AnimalsCells
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Smad3 initiates oxidative stress and proteolysis that underlies diaphragm dysfunction during mechanical ventilation. Sci Rep. 2017 11 06; 7(1):14530.
Tang H, L Kennedy C, Lee M, Gao Y, Xia H, Olguin F, Fraga DA, Ayers K, Choi S, Kim M, Tehrani A, Sowb YA, Rando TA, Shrager JB. PMID: 29109401; PMCID: PMC5673963.
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15 Fields:
Translation:
AnimalsCells
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Staufen1 inhibits MyoD translation to actively maintain muscle stem cell quiescence. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):E8996-E9005.
de Morrée A, van Velthoven CTJ, Gan Q, Salvi JS, Klein JDD, Akimenko I, Quarta M, Biressi S, Rando TA. PMID: 29073096; PMCID: PMC5664522.
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PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
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Macrophage-released ADAMTS1 promotes muscle stem cell activation. Nat Commun. 2017 09 22; 8(1):669.
Du H, Shih CH, Wosczyna MN, Mueller AA, Cho J, Aggarwal A, Rando TA, Feldman BJ. PMID: 28939843; PMCID: PMC5610267.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss. Nat Commun. 2017 06 20; 8:15613.
Quarta M, Cromie M, Chacon R, Blonigan J, Garcia V, Akimenko I, Hamer M, Paine P, Stok M, Shrager JB, Rando TA. PMID: 28631758; PMCID: PMC5481841.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimals
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HGFA Is an Injury-Regulated Systemic Factor that Induces the Transition of Stem Cells into GAlert. Cell Rep. 2017 04 18; 19(3):479-486.
Rodgers JT, Schroeder MD, Ma C, Rando TA. PMID: 28423312; PMCID: PMC5468096.
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73 Fields:
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AnimalsCells
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Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion. Aging Cell. 2017 06; 16(3):518-528.
Stearns-Reider KM, D'Amore A, Beezhold K, Rothrauff B, Cavalli L, Wagner WR, Vorp DA, Tsamis A, Shinde S, Zhang C, Barchowsky A, Rando TA, Tuan RS, Ambrosio F. PMID: 28371268; PMCID: PMC5418187.
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PubMed Mentions:
103 Fields:
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AnimalsCells
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Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c. Proc Natl Acad Sci U S A. 2017 04 11; 114(15):E3071-E3080.
Luo D, de Morree A, Boutet S, Quach N, Natu V, Rustagi A, Rando TA. PMID: 28351977; PMCID: PMC5393251.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Fleeting factors, turning back time. Nat Biotechnol. 2017 03 07; 35(3):218-220.
Rando TA. PMID: 28267729.
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HumansAnimals
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The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues. NPJ Regen Med. 2017; 2:4.
Smith AM, Maguire-Nguyen KK, Rando TA, Zasloff MA, Strange KB, Yin VP. PMID: 29302341; PMCID: PMC5677970.
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PubMed Mentions:
26
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Interaction between epigenetic and metabolism in aging stem cells. Curr Opin Cell Biol. 2017 04; 45:1-7.
Brunet A, Rando TA. PMID: 28129586; PMCID: PMC5482778.
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PubMed Mentions:
38 Fields:
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HumansAnimalsCells
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Intronic polyadenylation of PDGFRα in resident stem cells attenuates muscle fibrosis. Nature. 2016 12 08; 540(7632):276-279.
Mueller AA, van Velthoven CT, Fukumoto KD, Cheung TH, Rando TA. PMID: 27894125; PMCID: PMC5384334.
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PubMed Mentions:
65 Fields:
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AnimalsCells
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An artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy. Nat Biotechnol. 2016 07; 34(7):752-9.
Quarta M, Brett JO, DiMarco R, De Morree A, Boutet SC, Chacon R, Gibbons MC, Garcia VA, Su J, Shrager JB, Heilshorn S, Rando TA. PMID: 27240197; PMCID: PMC4942359.
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PubMed Mentions:
87 Fields:
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AnimalsCells
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UTX in muscle regeneration--the right dose and the right time. J Clin Invest. 2016 Apr 01; 126(4):1233-5.
Liu L, Rando TA. PMID: 26999609; PMCID: PMC4811162.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Stem cells and healthy aging. Science. 2015 Dec 04; 350(6265):1199-204.
Goodell MA, Rando TA. PMID: 26785478.
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PubMed Mentions:
143 Fields:
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HumansAnimalsCells
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H3K4me3 Breadth Is Linked to Cell Identity and Transcriptional Consistency. Cell. 2015 Nov 19; 163(5):1281-1286.
Benayoun BA, Pollina EA, Ucar D, Mahmoudi S, Karra K, Wong ED, Devarajan K, Daugherty AC, Kundaje AB, Mancini E, Hitz BC, Gupta R, Rando TA, Baker JC, Snyder MP, Cherry JM, Brunet A. PMID: 28930648.
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21 Fields:
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Isolation of skeletal muscle stem cells by fluorescence-activated cell sorting. Nat Protoc. 2015 Oct; 10(10):1612-24.
Liu L, Cheung TH, Charville GW, Rando TA. PMID: 26401916; PMCID: PMC4793971.
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PubMed Mentions:
169 Fields:
Translation:
AnimalsCells
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Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells. Stem Cell Reports. 2015 Oct 13; 5(4):621-32.
Charville GW, Cheung TH, Yoo B, Santos PJ, Lee GK, Shrager JB, Rando TA. PMID: 26344908; PMCID: PMC4624935.
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PubMed Mentions:
98 Fields:
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HumansAnimalsCells
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Mimicking the niche: cytokines expand muscle stem cells. Cell Res. 2015 Jul; 25(7):761-2.
Quarta M, Rando TA. PMID: 26113258; PMCID: PMC4493285.
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PubMed Mentions:
4 Fields:
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HumansAnimalsCells
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The JAK-STAT pathway is critical in ventilator-induced diaphragm dysfunction. Mol Med. 2015 Feb 19; 20:579-89.
Tang H, Smith IJ, Hussain SN, Goldberg P, Lee M, Sugiarto S, Godinez GL, Singh BK, Payan DG, Rando TA, Kinsella TM, Shrager JB. PMID: 25286450; PMCID: PMC4365068.
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PubMed Mentions:
27 Fields:
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HumansAnimalsCells
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Synergizing Engineering and Biology to Treat and Model Skeletal Muscle Injury and Disease. Annu Rev Biomed Eng. 2015; 17:217-42.
Bursac N, Juhas M, Rando TA. PMID: 26643021; PMCID: PMC4858326.
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PubMed Mentions:
22 Fields:
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HumansAnimalsCells
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A Wnt-TGFβ2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice. Sci Transl Med. 2014 Dec 17; 6(267):267ra176.
Biressi S, Miyabara EH, Gopinath SD, Carlig PM, Rando TA. PMID: 25520397; PMCID: PMC4350665.
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PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Geroscience: linking aging to chronic disease. Cell. 2014 Nov 06; 159(4):709-13.
Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, Wyss-Coray T, Sierra F. PMID: 25417146; PMCID: PMC4852871.
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PubMed Mentions:
990 Fields:
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HumansAnimals
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Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation. EMBO J. 2014 Dec 01; 33(23):2782-97.
Tang AH, Rando TA. PMID: 25316028; PMCID: PMC4282556.
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PubMed Mentions:
153 Fields:
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AnimalsCells
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Translational strategies and challenges in regenerative medicine. Nat Med. 2014 Aug; 20(8):814-21.
Dimmeler S, Ding S, Rando TA, Trounson A. PMID: 25100527.
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PubMed Mentions:
78 Fields:
Translation:
HumansCells
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H3K4me3 breadth is linked to cell identity and transcriptional consistency. Cell. 2014 Jul 31; 158(3):673-88.
Benayoun BA, Pollina EA, Ucar D, Mahmoudi S, Karra K, Wong ED, Devarajan K, Daugherty AC, Kundaje AB, Mancini E, Hitz BC, Gupta R, Rando TA, Baker JC, Snyder MP, Cherry JM, Brunet A. PMID: 25083876; PMCID: PMC4137894.
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PubMed Mentions:
261 Fields:
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HumansAnimalsCells
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Lineage of origin in rhabdomyosarcoma informs pharmacological response. Genes Dev. 2014 Jul 15; 28(14):1578-91.
Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, Brack AS, Wagers AJ, Rando TA, Capecchi MR, Marini FC, Ehler BR, Zarzabal LA, Goros MW, Michalek JE, Meltzer PS, Langenau DM, LeGallo RD, Mansoor A, Chen Y, Suelves M, Rubin BP, Keller C. PMID: 25030697; PMCID: PMC4102765.
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PubMed Mentions:
63 Fields:
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HumansAnimalsCells
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Alive and well? Exploring disease by studying lifespan. Curr Opin Genet Dev. 2014 Jun; 26:33-40.
Brett JO, Rando TA. PMID: 25005743; PMCID: PMC4253307.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Stem cells as vehicles for youthful regeneration of aged tissues. J Gerontol A Biol Sci Med Sci. 2014 Jun; 69 Suppl 1:S39-42.
Rando TA, Wyss-Coray T. PMID: 24833585; PMCID: PMC4022127.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert). Nature. 2014 Jun 19; 510(7505):393-6.
Rodgers JT, King KY, Brett JO, Cromie MJ, Charville GW, Maguire KK, Brunson C, Mastey N, Liu L, Tsai CR, Goodell MA, Rando TA. PMID: 24870234; PMCID: PMC4065227.
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PubMed Mentions:
353 Fields:
Translation:
AnimalsCells
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FOXO3 promotes quiescence in adult muscle stem cells during the process of self-renewal. Stem Cell Reports. 2014 Apr 08; 2(4):414-26.
Gopinath SD, Webb AE, Brunet A, Rando TA. PMID: 24749067; PMCID: PMC3986584.
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PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
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Regenerative medicine: Of fish and men. Nat Chem Biol. 2014 Feb; 10(2):91-2.
Rando TA. PMID: 24441638.
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Animals
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The CHC22 clathrin-GLUT4 transport pathway contributes to skeletal muscle regeneration. PLoS One. 2013; 8(10):e77787.
Hoshino S, Sakamoto K, Vassilopoulos S, Camus SM, Griffin CA, Esk C, Torres JA, Ohkoshi N, Ishii A, Tamaoka A, Funke BH, Kucherlapati R, Margeta M, Rando TA, Brodsky FM. PMID: 24204966; PMCID: PMC3813726.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Numb-deficient satellite cells have regeneration and proliferation defects. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18549-54.
George RM, Biressi S, Beres BJ, Rogers E, Mulia AK, Allen RE, Rawls A, Rando TA, Wilson-Rawls J. PMID: 24170859; PMCID: PMC3831958.
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PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
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Cardiac aging and rejuvenation--a sense of humors? N Engl J Med. 2013 Aug 08; 369(6):575-6.
Rando TA, Finkel T. PMID: 23924010.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis. Cell Rep. 2013 Aug 15; 4(3):477-91.
Webb AE, Pollina EA, Vierbuchen T, Urbán N, Ucar D, Leeman DS, Martynoga B, Sewak M, Rando TA, Guillemot F, Wernig M, Brunet A. PMID: 23891001; PMCID: PMC3838667.
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PubMed Mentions:
92 Fields:
Translation:
AnimalsCells
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Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging. Cell Rep. 2013 Jul 11; 4(1):189-204.
Liu L, Cheung TH, Charville GW, Hurgo BM, Leavitt T, Shih J, Brunet A, Rando TA. PMID: 23810552; PMCID: PMC4103025.
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PubMed Mentions:
280 Fields:
Translation:
AnimalsCells
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A sexy spin on nonrandom chromosome segregation. Cell Stem Cell. 2013 Jun 06; 12(6):641-3.
Charville GW, Rando TA. PMID: 23746972; PMCID: PMC3715869.
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AnimalsCells
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Molecular regulation of stem cell quiescence. Nat Rev Mol Cell Biol. 2013 Jun; 14(6):329-40.
Cheung TH, Rando TA. PMID: 23698583; PMCID: PMC3808888.
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PubMed Mentions:
543 Fields:
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HumansAnimalsCells
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The mortal strand hypothesis: non-random chromosome inheritance and the biased segregation of damaged DNA. Semin Cell Dev Biol. 2013 Aug-Sep; 24(8-9):653-60.
Charville GW, Rando TA. PMID: 23701893; PMCID: PMC3786026.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Myf5 expression during fetal myogenesis defines the developmental progenitors of adult satellite cells. Dev Biol. 2013 Jul 15; 379(2):195-207.
Biressi S, Bjornson CR, Carlig PM, Nishijo K, Keller C, Rando TA. PMID: 23639729; PMCID: PMC3679295.
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PubMed Mentions:
45 Fields:
Translation:
AnimalsCells
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Assessment of disease activity in muscular dystrophies by noninvasive imaging. J Clin Invest. 2013 May; 123(5):2298-305.
Maguire KK, Lim L, Speedy S, Rando TA. PMID: 23619364; PMCID: PMC3638910.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration. Cell. 2013 Apr 11; 153(2):376-88.
Heredia JE, Mukundan L, Chen FM, Mueller AA, Deo RC, Locksley RM, Rando TA, Chawla A. PMID: 23582327; PMCID: PMC3663598.
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PubMed Mentions:
398 Fields:
Translation:
AnimalsCells
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Heterochronic parabiosis: historical perspective and methodological considerations for studies of aging and longevity. Aging Cell. 2013 Jun; 12(3):525-30.
Conboy MJ, Conboy IM, Rando TA. PMID: 23489470; PMCID: PMC4072458.
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PubMed Mentions:
123 Fields:
Translation:
AnimalsCells
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All's well that ends well: alternative polyadenylation and its implications for stem cell biology. Curr Opin Cell Biol. 2013 Apr; 25(2):222-32.
Mueller AA, Cheung TH, Rando TA. PMID: 23357469; PMCID: PMC3615088.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Guest editorial: emergent themes from second annual symposium on regenerative rehabilitation, Pittsburgh, Pennsylvania. J Rehabil Res Dev. 2013; 50(3):vii-xiv.
Ambrosio F, Boninger ML, Brubaker CE, Delitto A, Wagner WR, Shields RK, Wolf SL, Rando TA. PMID: 23881770; PMCID: PMC4018824.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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The ins and outs of aging and longevity. Annu Rev Physiol. 2013; 75:617-9.
Rando TA. PMID: 23398156.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Collagen VI regulates satellite cell self-renewal and muscle regeneration. Nat Commun. 2013; 4:1964.
Urciuolo A, Quarta M, Morbidoni V, Gattazzo F, Molon S, Grumati P, Montemurro F, Tedesco FS, Blaauw B, Cossu G, Vozzi G, Rando TA, Bonaldo P. PMID: 23743995; PMCID: PMC3682802.
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PubMed Mentions:
225 Fields:
Translation:
AnimalsCells
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Sprouting a new take on stem cell aging. EMBO J. 2012 Nov 05; 31(21):4103-5.
Rodgers JT, Rando TA. PMID: 23042560; PMCID: PMC3492738.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Recent advances in the pathogenesis and treatment of neuromuscular diseases. Curr Opin Neurol. 2012 Oct; 25(5):586-7.
Rando TA. PMID: 22892955.
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PubMed Mentions:
2 Fields:
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HumansAnimals
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The place of genetics in ageing research. Nat Rev Genet. 2012 07 10; 13(8):589-94.
Barzilai N, Guarente L, Kirkwood TB, Partridge L, Rando TA, Slagboom PE. PMID: 22777128.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches. Cell Cycle. 2012 Jun 15; 11(12):2260-7.
Conboy IM, Rando TA. PMID: 22617385; PMCID: PMC3383588.
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PubMed Mentions:
113 Fields:
Translation:
HumansAnimalsCells
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Tissue-specific stem cells: lessons from the skeletal muscle satellite cell. Cell Stem Cell. 2012 May 04; 10(5):504-14.
Brack AS, Rando TA. PMID: 22560074; PMCID: PMC3348769.
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PubMed Mentions:
209 Fields:
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HumansAnimalsCells
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Losartan improves adipose tissue-derived stem cell niche by inhibiting transforming growth factor-β and fibrosis in skeletal muscle injury. Cell Transplant. 2012; 21(11):2407-24.
Park JK, Ki MR, Lee EM, Kim AY, You SY, Han SY, Lee EJ, Hong IH, Kwon SH, Kim SJ, Rando TA, Jeong KS. PMID: 22507443.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Alternative polyadenylation mediates microRNA regulation of muscle stem cell function. Cell Stem Cell. 2012 Mar 02; 10(3):327-36.
Boutet SC, Cheung TH, Quach NL, Liu L, Prescott SL, Edalati A, Iori K, Rando TA. PMID: 22385659; PMCID: PMC3306803.
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PubMed Mentions:
96 Fields:
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HumansAnimalsCells
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Maintenance of muscle stem-cell quiescence by microRNA-489. Nature. 2012 Feb 23; 482(7386):524-8.
Cheung TH, Quach NL, Charville GW, Liu L, Park L, Edalati A, Yoo B, Hoang P, Rando TA. PMID: 22358842; PMCID: PMC3292200.
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PubMed Mentions:
236 Fields:
Translation:
AnimalsCells
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Notch signaling is necessary to maintain quiescence in adult muscle stem cells. Stem Cells. 2012 Feb; 30(2):232-42.
Bjornson CR, Cheung TH, Liu L, Tripathi PV, Steeper KM, Rando TA. PMID: 22045613; PMCID: PMC3384696.
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PubMed Mentions:
269 Fields:
Translation:
AnimalsCells
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Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell. 2012 Jan 20; 148(1-2):46-57.
Rando TA, Chang HY. PMID: 22265401; PMCID: PMC3336960.
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PubMed Mentions:
227 Fields:
Translation:
HumansAnimals
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The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature. 2011 Aug 31; 477(7362):90-4.
Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T. PMID: 21886162; PMCID: PMC3170097.
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PubMed Mentions:
875 Fields:
Translation:
Animals
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Emerging models and paradigms for stem cell ageing. Nat Cell Biol. 2011 May; 13(5):506-12.
Jones DL, Rando TA. PMID: 21540846; PMCID: PMC3257978.
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PubMed Mentions:
110 Fields:
Translation:
HumansAnimalsCells
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Manifestations and mechanisms of stem cell aging. J Cell Biol. 2011 Apr 18; 193(2):257-66.
Liu L, Rando TA. PMID: 21502357; PMCID: PMC3080271.
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PubMed Mentions:
143 Fields:
Translation:
HumansAnimalsCells
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Stem cell ageing and non-random chromosome segregation. Philos Trans R Soc Lond B Biol Sci. 2011 Jan 12; 366(1561):85-93.
Charville GW, Rando TA. PMID: 21115534; PMCID: PMC3001309.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Taf1 regulates Pax3 protein by monoubiquitination in skeletal muscle progenitors. Mol Cell. 2010 Dec 10; 40(5):749-61.
Boutet SC, Biressi S, Iori K, Natu V, Rando TA. PMID: 21145483; PMCID: PMC3023311.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Heterogeneity in the muscle satellite cell population. Semin Cell Dev Biol. 2010 Oct; 21(8):845-54.
Biressi S, Rando TA. PMID: 20849971; PMCID: PMC2967620.
View in:
PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Impact papers on aging in 2009. Aging (Albany NY). 2010 Mar; 2(3):111-21.
Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, Hall MN, Hekimi S, Helfand SL, Karlseder J, Kenyon C, Kroemer G, Longo V, Nussenzweig A, Osiewacz HD, Peeper DS, Rando TA, Rudolph KL, Sassone-Corsi P, Serrano M, Sharpless NE, Skulachev VP, Tilly JL, Tower J, Verdin E, Vijg J. PMID: 20351400; PMCID: PMC2871240.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Epigenetics and aging. Exp Gerontol. 2010 Apr; 45(4):253-4.
Rando TA. PMID: 20034555; PMCID: PMC2838984.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Enhanced gene repair mediated by methyl-CpG-modified single-stranded oligonucleotides. Nucleic Acids Res. 2009 Dec; 37(22):7468-82.
Bertoni C, Rustagi A, Rando TA. PMID: 19854937; PMCID: PMC2794159.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration. Dev Biol. 2009 Nov 01; 335(1):93-105.
Brack AS, Murphy-Seiler F, Hanifi J, Deka J, Eyckerman S, Keller C, Aguet M, Rando TA. PMID: 19699733; PMCID: PMC3259687.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Focal adhesion kinase signaling regulates the expression of caveolin 3 and beta1 integrin, genes essential for normal myoblast fusion. Mol Biol Cell. 2009 Jul; 20(14):3422-35.
Quach NL, Biressi S, Reichardt LF, Keller C, Rando TA. PMID: 19458188; PMCID: PMC2710835.
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PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
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Biomarker system for studying muscle, stem cells, and cancer in vivo. FASEB J. 2009 Aug; 23(8):2681-90.
Nishijo K, Hosoyama T, Bjornson CR, Schaffer BS, Prajapati SI, Bahadur AN, Hansen MS, Blandford MC, McCleish AT, Rubin BP, Epstein JA, Rando TA, Capecchi MR, Keller C. PMID: 19332644; PMCID: PMC2717773.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
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Preventing oxidative stress: a new role for XBP1. Cell Death Differ. 2009 Jun; 16(6):847-57.
Liu Y, Adachi M, Zhao S, Hareyama M, Koong AC, Luo D, Rando TA, Imai K, Shinomura Y. PMID: 19247368; PMCID: PMC2826168.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Turning back time: reversing tissue pathology to enhance stem cell engraftment. Cell Stem Cell. 2008 Sep 11; 3(3):232-4.
Rando TA. PMID: 18786408.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Stem cell review series: aging of the skeletal muscle stem cell niche. Aging Cell. 2008 Aug; 7(4):590-8.
Gopinath SD, Rando TA. PMID: 18462272.
View in:
PubMed Mentions:
127 Fields:
Translation:
HumansAnimalsCells
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Tissue ageing: do insights into molecular mechanisms of ageing lead to new therapeutic strategies? Exp Gerontol. 2008 Jul; 43(7):603-604.
Simm A, Rando TA. PMID: 18599230; PMCID: PMC2536625.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Get personal with gene therapy for muscular dystrophy. Lancet Neurol. 2008 Mar; 7(3):196-8.
Rando TA. PMID: 18275918.
View in:
PubMed Mentions: Fields:
Translation:
Humans
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Technology insight: therapy for Duchenne muscular dystrophy-an opportunity for personalized medicine? Nat Clin Pract Neurol. 2008 Mar; 4(3):149-58.
Lim LE, Rando TA. PMID: 18268530.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell. 2008 Jan 10; 2(1):50-9.
Brack AS, Conboy IM, Conboy MJ, Shen J, Rando TA. PMID: 18371421.
View in:
PubMed Mentions:
314 Fields:
Translation:
HumansAnimalsCells
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[Proteasomal degradation of Pax3 in skeletal muscle progenitors: one ubiquitin does the trick!]. Med Sci (Paris). 2008 Jan; 24(1):31-3.
Boutet SC, Rando TA. PMID: 18198106.
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PubMed Mentions: Fields:
Translation:
Humans
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Ageing: from stem to stern. Nature. 2007 Sep 20; 449(7160):288-91.
Brunet A, Rando TA. PMID: 17882206.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science. 2007 Aug 10; 317(5839):807-10.
Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, Rando TA. PMID: 17690295.
View in:
PubMed Mentions:
742 Fields:
Translation:
AnimalsCells
-
Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors. Cell. 2007 Jul 27; 130(2):349-62.
Boutet SC, Disatnik MH, Chan LS, Iori K, Rando TA. PMID: 17662948.
View in:
PubMed Mentions:
91 Fields:
Translation:
AnimalsCells
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The immortal strand hypothesis: segregation and reconstruction. Cell. 2007 Jun 29; 129(7):1239-43.
Rando TA. PMID: 17604710.
View in:
PubMed Mentions:
76 Fields:
Translation:
HumansAnimalsCells
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High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. PLoS Biol. 2007 May; 5(5):e102.
Conboy MJ, Karasov AO, Rando TA. PMID: 17439301; PMCID: PMC1852584.
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PubMed Mentions:
136 Fields:
Translation:
AnimalsCells
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Intrinsic changes and extrinsic influences of myogenic stem cell function during aging. Stem Cell Rev. 2007; 3(3):226-37.
Brack AS, Rando TA. PMID: 17917136.
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PubMed Mentions:
111 Fields:
Translation:
HumansAnimalsCells
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Long-term increase in mVEGF164 in mouse hindlimb muscle mediated by phage phiC31 integrase after nonviral DNA delivery. Hum Gene Ther. 2006 Aug; 17(8):871-6.
Portlock JL, Keravala A, Bertoni C, Lee S, Rando TA, Calos MP. PMID: 16942446.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Prognostic value of telomere length: the long and short of it. Ann Neurol. 2006 Aug; 60(2):155-7.
Rando TA. PMID: 16862590.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Non-viral gene therapy for Duchenne muscular dystrophy: progress and challenges. Biochim Biophys Acta. 2007 Feb; 1772(2):263-71.
Rando TA. PMID: 17005381.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Stem cells, ageing and the quest for immortality. Nature. 2006 Jun 29; 441(7097):1080-6.
Rando TA. PMID: 16810243.
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PubMed Mentions:
271 Fields:
Translation:
HumansAnimalsCells
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Altered caveolin-3 expression disrupts PI(3) kinase signaling leading to death of cultured muscle cells. Exp Cell Res. 2006 Sep 10; 312(15):2816-25.
Smythe GM, Rando TA. PMID: 16814768.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Focal adhesion kinase is essential for costamerogenesis in cultured skeletal muscle cells. Dev Biol. 2006 May 01; 293(1):38-52.
Quach NL, Rando TA. PMID: 16533505.
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PubMed Mentions:
50 Fields:
Translation:
AnimalsCells
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Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration. Proc Natl Acad Sci U S A. 2006 Jan 10; 103(2):419-24.
Bertoni C, Jarrahian S, Wheeler TM, Li Y, Olivares EC, Calos MP, Rando TA. PMID: 16387861; PMCID: PMC1326153.
View in:
PubMed Mentions:
38 Fields:
Translation:
Animals
-
Stem cells in postnatal myogenesis: molecular mechanisms of satellite cell quiescence, activation and replenishment. Trends Cell Biol. 2005 Dec; 15(12):666-73.
Dhawan J, Rando TA. PMID: 16243526.
View in:
PubMed Mentions:
196 Fields:
Translation:
HumansAnimalsCells
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The adult muscle stem cell comes of age. Nat Med. 2005 Aug; 11(8):829-31.
Rando TA. PMID: 16079875.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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The regulation of Notch signaling in muscle stem cell activation and postnatal myogenesis. Semin Cell Dev Biol. 2005 Aug-Oct; 16(4-5):612-22.
Luo D, Renault VM, Rando TA. PMID: 16087370.
View in:
PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Aging, stem cells and tissue regeneration: lessons from muscle. Cell Cycle. 2005 Mar; 4(3):407-10.
Conboy IM, Rando TA. PMID: 15725724.
View in:
PubMed Mentions:
122 Fields:
Translation:
HumansAnimalsCells
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NF90 regulates cell cycle exit and terminal myogenic differentiation by direct binding to the 3'-untranslated region of MyoD and p21WAF1/CIP1 mRNAs. J Biol Chem. 2005 May 13; 280(19):18981-9.
Shi L, Zhao G, Qiu D, Godfrey WR, Vogel H, Rando TA, Hu H, Kao PN. PMID: 15746098.
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PubMed Mentions:
60 Fields:
Translation:
AnimalsCells
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Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature. 2005 Feb 17; 433(7027):760-4.
Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA. PMID: 15716955.
View in:
PubMed Mentions:
962 Fields:
Translation:
AnimalsCells
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Strand bias in oligonucleotide-mediated dystrophin gene editing. Hum Mol Genet. 2005 Jan 15; 14(2):221-33.
Bertoni C, Morris GE, Rando TA. PMID: 15563511.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle. Cell. 2004 Nov 12; 119(4):543-54.
Sherwood RI, Christensen JL, Conboy IM, Conboy MJ, Rando TA, Weissman IL, Wagers AJ. PMID: 15537543.
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PubMed Mentions:
212 Fields:
Translation:
AnimalsCells
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Artificial sweeteners--enhancing glycosylation to treat muscular dystrophies. N Engl J Med. 2004 Sep 16; 351(12):1254-6.
Rando TA. PMID: 15371584.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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The bi-directional translocation of MARCKS between membrane and cytosol regulates integrin-mediated muscle cell spreading. J Cell Sci. 2004 09 01; 117(Pt 19):4469-79.
Disatnik MH, Boutet SC, Pacio W, Chan AY, Ross LB, Lee CH, Rando TA. PMID: 15316066.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
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A caveolin-3 mutant that causes limb girdle muscular dystrophy type 1C disrupts Src localization and activity and induces apoptosis in skeletal myotubes. J Cell Sci. 2003 Dec 01; 116(Pt 23):4739-49.
Smythe GM, Eby JC, Disatnik MH, Rando TA. PMID: 14600260.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Notch-mediated restoration of regenerative potential to aged muscle. Science. 2003 Nov 28; 302(5650):1575-7.
Conboy IM, Conboy MJ, Smythe GM, Rando TA. PMID: 14645852.
View in:
PubMed Mentions:
443 Fields:
Translation:
AnimalsCells
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Late-onset distal muscular dystrophy affecting the posterior calves. Muscle Nerve. 2003 Oct; 28(4):443-8.
Katz JS, Rando TA, Barohn RJ, Saperstein DS, Jackson CE, Wicklund M, Amato AA. PMID: 14506716.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Remarkable preservation of undigested muscle tissue within a Late Cretaceous tyrannosaurid coprolite from Alberta, Canada. Palaios. 2003 Jun; 18(3):286-94.
Chin K, Eberth DA, Schweitzer MH, Rando TA, Sloboda WJ, Horner JR. PMID: 12866547.
View in:
PubMed Mentions:
15 Translation:
Animals
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Restoration of dystrophin expression in mdx muscle cells by chimeraplast-mediated exon skipping. Hum Mol Genet. 2003 May 15; 12(10):1087-99.
Bertoni C, Lau C, Rando TA. PMID: 12719373.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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The regulation of catalase gene expression in mouse muscle cells is dependent on the CCAAT-binding factor NF-Y. Biochem Biophys Res Commun. 2003 Apr 04; 303(2):609-18.
Luo D, Rando TA. PMID: 12659863.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Oxidative stress and the pathogenesis of muscular dystrophies. Am J Phys Med Rehabil. 2002 Nov; 81(11 Suppl):S175-86.
Rando TA. PMID: 12409822.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Oligonucleotide-mediated gene therapy for muscular dystrophies. Neuromuscul Disord. 2002 Oct; 12 Suppl 1:S55-60.
Rando TA. PMID: 12206797.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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The regulation of Notch signaling controls satellite cell activation and cell fate determination in postnatal myogenesis. Dev Cell. 2002 Sep; 3(3):397-409.
Conboy IM, Rando TA. PMID: 12361602.
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PubMed Mentions:
366 Fields:
Translation:
AnimalsCells
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The modulation of cellular susceptibility to oxidative stress: protective and destructive actions of Cu,Zn-superoxide dismutase. Neurobiol Dis. 2002 Aug; 10(3):234-46.
Xing J, Yu Y, Rando TA. PMID: 12270686.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Sequential activation of individual PKC isozymes in integrin-mediated muscle cell spreading: a role for MARCKS in an integrin signaling pathway. J Cell Sci. 2002 05 15; 115(Pt 10):2151-63.
Disatnik MH, Boutet SC, Lee CH, Mochly-Rosen D, Rando TA. PMID: 11973356.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Dystrophin gene repair in mdx muscle precursor cells in vitro and in vivo mediated by RNA-DNA chimeric oligonucleotides. Hum Gene Ther. 2002 Apr 10; 13(6):707-18.
Bertoni C, Rando TA. PMID: 11936970.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Activation of an adipogenic program in adult myoblasts with age. Mech Ageing Dev. 2002 Mar 31; 123(6):649-61.
Taylor-Jones JM, McGehee RE, Rando TA, Lecka-Czernik B, Lipschitz DA, Peterson CA. PMID: 11850028.
View in:
PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Gene delivery to muscle. Curr Protoc Hum Genet. 2002 Feb; Chapter 13:Unit13.4.
Springer ML, Rando TA, Blau HM. PMID: 18428326.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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The dystrophin-glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies. Muscle Nerve. 2001 Dec; 24(12):1575-94.
Rando TA. PMID: 11745966.
View in:
PubMed Mentions:
116 Fields:
Translation:
HumansAnimalsCells
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NF kappa B and AP-1 mediate transcriptional responses to oxidative stress in skeletal muscle cells. Free Radic Biol Med. 2001 Dec 01; 31(11):1405-16.
Zhou LZ, Johnson AP, Rando TA. PMID: 11728812.
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PubMed Mentions:
98 Fields:
Translation:
AnimalsCells
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Role of nitric oxide in the pathogenesis of muscular dystrophies: a "two hit" hypothesis of the cause of muscle necrosis. Microsc Res Tech. 2001 Nov 15; 55(4):223-35.
Rando TA. PMID: 11748861.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimals
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The susceptibility of muscle cells to oxidative stress is independent of nitric oxide synthase expression. Muscle Nerve. 2001 Apr; 24(4):502-11.
Zhuang W, Eby JC, Cheong M, Mohapatra PK, Bredt DS, Disatnik MH, Rando TA. PMID: 11268022.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides. Proc Natl Acad Sci U S A. 2000 May 09; 97(10):5363-8.
Rando TA, Disatnik MH, Zhou LZ. PMID: 10805797; PMCID: PMC25834.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Dystrophin mutations predict cellular susceptibility to oxidative stress. Muscle Nerve. 2000 May; 23(5):784-92.
Disatnik MH, Chamberlain JS, Rando TA. PMID: 10797403.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Neuromuscular disorders of childhood. Curr Opin Pediatr. 1999 Dec; 11(6):497-503.
Andersson PB, Rando TA. PMID: 10590906.
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PubMed Mentions:
5 Translation:
Humans
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Integrin-mediated muscle cell spreading. The role of protein kinase c in outside-in and inside-out signaling and evidence of integrin cross-talk. J Biol Chem. 1999 Nov 05; 274(45):32486-92.
Disatnik MH, Rando TA. PMID: 10542294.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Regulation of antioxidant enzyme gene expression in response to oxidative stress and during differentiation of mouse skeletal muscle. Free Radic Biol Med. 1999 Nov; 27(9-10):1122-32.
Franco AA, Odom RS, Rando TA. PMID: 10569645.
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PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Copper/zinc superoxide dismutase: more is not necessarily better! Ann Neurol. 1999 Jul; 46(1):135-6.
Rando TA, Epstein CJ. PMID: 10401795.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Evidence of oxidative stress in mdx mouse muscle: studies of the pre-necrotic state. J Neurol Sci. 1998 Nov 26; 161(1):77-84.
Disatnik MH, Dhawan J, Yu Y, Beal MF, Whirl MM, Franco AA, Rando TA. PMID: 9879685.
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PubMed Mentions:
71 Fields:
Translation:
Animals
-
Dystrophic muscle in mice chimeric for expression of alpha5 integrin. J Cell Biol. 1998 Nov 02; 143(3):849-59.
Taverna D, Disatnik MH, Rayburn H, Bronson RT, Yang J, Rando TA, Hynes RO. PMID: 9813102; PMCID: PMC2148145.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Overexpression of copper/zinc superoxide dismutase: a novel cause of murine muscular dystrophy. Ann Neurol. 1998 Sep; 44(3):381-6.
Rando TA, Crowley RS, Carlson EJ, Epstein CJ, Mohapatra PK. PMID: 9749606.
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PubMed Mentions:
20 Fields:
Translation:
Animals
-
Heterogeneity among muscle precursor cells in adult skeletal muscles with differing regenerative capacities. Dev Dyn. 1998 Aug; 212(4):495-508.
Pavlath GK, Thaloor D, Rando TA, Cheong M, English AW, Zheng B. PMID: 9707323.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Two regions of the ryanodine receptor involved in coupling with L-type Ca2+ channels. J Biol Chem. 1998 May 29; 273(22):13403-6.
Nakai J, Sekiguchi N, Rando TA, Allen PD, Beam KG. PMID: 9593671.
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PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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Muscle cells from mdx mice have an increased susceptibility to oxidative stress. Neuromuscul Disord. 1998 Feb; 8(1):14-21.
Rando TA, Disatnik MH, Yu Y, Franco A. PMID: 9565986.
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PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
-
Methods for myoblast transplantation. Methods Cell Biol. 1997; 52:261-72.
Rando TA, Blau HM. PMID: 9379953.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Genetic analysis of alpha 4 integrin functions in the development of mouse skeletal muscle. J Cell Biol. 1996 Nov; 135(3):829-35.
Yang JT, Rando TA, Mohler WA, Rayburn H, Blau HM, Hynes RO. PMID: 8909554; PMCID: PMC2121061.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Myoblast-mediated expression of colony stimulating factor-1 (CSF-1) in the cytokine-deficient op/op mouse. Somat Cell Mol Genet. 1996 Sep; 22(5):363-81.
Dhawan J, Rando TA, Elson SE, Lee F, Stanley ER, Blau HM. PMID: 9039846.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
The fate of myoblasts following transplantation into mature muscle. Exp Cell Res. 1995 Oct; 220(2):383-9.
Rando TA, Pavlath GK, Blau HM. PMID: 7556447.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Tetracycline-regulated gene expression following direct gene transfer into mouse skeletal muscle. Somat Cell Mol Genet. 1995 Jul; 21(4):233-40.
Dhawan J, Rando TA, Elson SL, Bujard H, Blau HM. PMID: 8525429.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Transient immunosuppressive treatment leads to long-term retention of allogeneic myoblasts in hybrid myofibers. J Cell Biol. 1994 Dec; 127(6 Pt 2):1923-32.
Pavlath GK, Rando TA, Blau HM. PMID: 7806570; PMCID: PMC2120274.
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PubMed Mentions:
14 Fields:
Translation:
Animals
-
Pseudochoreoathetosis. Movements associated with loss of proprioception. Arch Neurol. 1994 Nov; 51(11):1103-9.
Sharp FR, Rando TA, Greenberg SA, Brown L, Sagar SM. PMID: 7980104.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J Cell Biol. 1994 Jun; 125(6):1275-87.
Rando TA, Blau HM. PMID: 8207057; PMCID: PMC2290930.
View in:
PubMed Mentions:
416 Fields:
Translation:
AnimalsCells
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Tumor suppression by RNA from the 3' untranslated region of alpha-tropomyosin. Cell. 1993 Dec 17; 75(6):1107-17.
Rastinejad F, Conboy MJ, Rando TA, Blau HM. PMID: 7505203.
View in:
PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
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Wolfram syndrome: evidence of a diffuse neurodegenerative disease by magnetic resonance imaging. Neurology. 1992 Jun; 42(6):1220-4.
Rando TA, Horton JC, Layzer RB. PMID: 1603350.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Spontaneous intracranial hypotension: report of two cases and review of the literature. Neurology. 1992 Mar; 42(3 Pt 1):481-7.
Rando TA, Fishman RA. PMID: 1549206.
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PubMed Mentions:
55 Fields:
Translation:
Humans
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Progressive multifocal leukoencephalopathy in persons infected with human immunodeficiency virus, San Francisco, 1981-1989. Ann Neurol. 1991 Oct; 30(4):597-604.
Gillespie SM, Chang Y, Lemp G, Arthur R, Buchbinder S, Steimle A, Baumgartner J, Rando T, Neal D, Rutherford G, et al. PMID: 1665053.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Rapid and slow gating of veratridine-modified sodium channels in frog myelinated nerve. J Gen Physiol. 1989 Jan; 93(1):43-65.
Rando TA. PMID: 2536798; PMCID: PMC2216201.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Anticipatory grief: the term is a misnomer but the phenomenon exists. J Palliat Care. 1988 May; 4(1-2):70-3.
Rando TA. PMID: 3171779.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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The unrecognized impact of sudden death in terminal illness and in positively progressing convalescence. Isr J Psychiatry Relat Sci. 1987; 24(1-2):125-35.
Rando TA. PMID: 3443538.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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An integrated view of the molecular toxinology of sodium channel gating in excitable cells. Annu Rev Neurosci. 1987; 10:237-67.
Strichartz G, Rando T, Wang GK. PMID: 2436544.
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PubMed Mentions:
42 Fields:
Translation:
Animals
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The interaction between the activator agents batrachotoxin and veratridine and the gating processes of neuronal sodium channels. Mol Pharmacol. 1986 May; 29(5):467-77.
Rando TA, Wang GK, Strichartz GR. PMID: 2422536.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Saxitoxin blocks batrachotoxin-modified sodium channels in the node of Ranvier in a voltage-dependent manner. Biophys J. 1986 Mar; 49(3):785-94.
Rando TA, Strichartz GR. PMID: 2421797; PMCID: PMC1329526.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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On the mechanism by which saxitoxin binds to and blocks sodium channels. Ann N Y Acad Sci. 1986; 479:96-112.
Strichartz G, Rando T, Hall S, Gitschier J, Hall L, Magnani B, Bay CH. PMID: 2434011.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Bereaved parents: particular difficulties, unique factors, and treatment issues. Soc Work. 1985 Jan-Feb; 30(1):19-23.
Rando TA. PMID: 10270480.
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Translation:
Humans
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An investigation of grief and adaptation in parents whose children have died from cancer. J Pediatr Psychol. 1983 Mar; 8(1):3-20.
Rando TA. PMID: 6842349.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Localization of neurons in the rat spinal cord which project to the superior cervical ganglion. J Comp Neurol. 1981 Feb 10; 196(1):73-83.
Rando TA, Bowers CW, Zigmond RE. PMID: 7204667.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells