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David Yao

Title(s)HS Assistant Clinical Professor, Urology
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network. Cell Death Differ. 2025 Apr 22. Boutelle AM, Mabene AR, Yao D, Xu H, Wang M, Tang YJ, Lopez SS, Sinha S, Demeter J, Cheng R, Benard BA, McCrea EM, Valente LJ, Drainas AP, Fischer M, Majeti R, Petrov DA, Jackson PK, Yang F, Winslow MM, Bassik MC, Attardi LD. PMID: 40263541.
      View in: PubMed   Mentions:    Fields:    
    2. Long-range regulation of transcription scales with genomic distance in a gene-specific manner. Mol Cell. 2025 Jan 16; 85(2):347-361.e7. Jensen CL, Chen LF, Swigut T, Crocker OJ, Yao D, Bassik MC, Ferrell JE, Boettiger AN, Wysocka J. PMID: 39626660; PMCID: PMC11741922.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    3. Development of compact transcriptional effectors using high-throughput measurements in diverse contexts. Nat Biotechnol. 2025 Sep; 43(9):1525-1538. Tycko J, Van MV, DelRosso N, Ye H, Yao D, Valbuena R, Vaughan-Jackson A, Xu X, Ludwig C, Spees K, Liu K, Gu M, Khare V, Mukund AX, Suzuki PH, Arana S, Zhang C, Du PP, Ornstein TS, Hess GT, Kamber RA, Qi LS, Khalil AS, Bintu L, Bassik MC. PMID: 39487265; PMCID: PMC12043968.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    4. Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment. Nature. 2023 10; 622(7982):359-366. Meng X, Yao D, Imaizumi K, Chen X, Kelley KW, Reis N, Thete MV, Arjun McKinney A, Kulkarni S, Panagiotakos G, Bassik MC, Pa?ca SP. PMID: 37758944; PMCID: PMC10567561.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    5. Death-seq identifies regulators of cell death and senolytic therapies. Cell Metab. 2023 10 03; 35(10):1814-1829.e6. Colville A, Liu JY, Rodriguez-Mateo C, Thomas S, Ishak HD, Zhou R, Klein JDD, Morgens DW, Goshayeshi A, Salvi JS, Yao D, Spees K, Dixon SJ, Liu C, Rhee JW, Lai C, Wu JC, Bassik MC, Rando TA. PMID: 37699398; PMCID: PMC10597643.
      View in: PubMed   Mentions: 14     Fields:    
    6. Programmable multi-kilobase RNA editing using CRISPR-mediated trans-splicing. bioRxiv. 2023 Aug 18. Borrajo J, Javanmardi K, Griffin J, St Martin SJ, Yao D, Hill K, Blainey PC, Al-Shayeb B. PMID: 37645763; PMCID: PMC10462116.
      View in: PubMed   Mentions:
    7. Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis. Nature. 2021 09; 597(7877):549-554. Kamber RA, Nishiga Y, Morton B, Banuelos AM, Barkal AA, Vences-Catalán F, Gu M, Fernandez D, Seoane JA, Yao D, Liu K, Lin S, Spees K, Curtis C, Jerby-Arnon L, Weissman IL, Sage J, Bassik MC. PMID: 34497417; PMCID: PMC9419706.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    8. An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens. Elife. 2021 08 20; 10. Coukos R, Yao D, Sanchez MI, Strand ET, Olive ME, Udeshi ND, Weissman JS, Carr SA, Bassik MC, Ting AY. PMID: 34414886; PMCID: PMC8423448.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    9. High-Throughput Discovery and Characterization of Human Transcriptional Effectors. Cell. 2020 12 23; 183(7):2020-2035.e16. Tycko J, DelRosso N, Hess GT, Banerjee A, Mukund A, Van MV, Ego BK, Yao D, Spees K, Suzuki P, Marinov GK, Kundaje A, Bassik MC, Bintu L. PMID: 33326746; PMCID: PMC8178797.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    10. CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities. Nature. 2020 04; 580(7801):136-141. Han K, Pierce SE, Li A, Spees K, Anderson GR, Seoane JA, Lo YH, Dubreuil M, Olivas M, Kamber RA, Wainberg M, Kostyrko K, Kelly MR, Yousefi M, Simpkins SW, Yao D, Lee K, Kuo CJ, Jackson PK, Sweet-Cordero A, Kundaje A, Gentles AJ, Curtis C, Winslow MM, Bassik MC. PMID: 32238925; PMCID: PMC7368463.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansAnimalsCells
    11. Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins. Elife. 2019 11 01; 8. Morgens DW, Chan C, Kane AJ, Weir NR, Li A, Dubreuil MM, Tsui CK, Hess GT, Lavertu A, Han K, Polyakov N, Zhou J, Handy EL, Alabi P, Dombroski A, Yao D, Altman RB, Sello JK, Denic V, Bassik MC. PMID: 31674906; PMCID: PMC6858068.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    12. Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements. Nat Commun. 2019 Sep 06; 10(1):4063. Tycko J, Wainberg M, Marinov GK, Ursu O, Hess GT, Ego BK, Li A, Truong A, Trevino AE, Spees K, Yao D, Kaplow IM, Greenside PG, Morgens DW, Phanstiel DH, Snyder MP, Bintu L, Greenleaf WJ, Kundaje A, Bassik MC. PMID: 31492858; PMCID: PMC6731277.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    13. A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions. Mol Cell. 2019 01 03; 73(1):183-194.e8. Chong R, Insigne KD, Yao D, Burghard CP, Wang J, Hsiao YE, Jones EM, Goodman DB, Xiao X, Kosuri S. PMID: 30503770; PMCID: PMC6599603.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    14. Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes. Mol Cell. 2017 Oct 05; 68(1):26-43. Hess GT, Tycko J, Yao D, Bassik MC. PMID: 28985508; PMCID: PMC5997582.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    15. Diving for drugs: tunicate anticancer compounds. Drug Discov Today. 2012 Jun; 17(11-12):636-48. Cooper EL, Yao D. PMID: 22406646.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
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