Lili Yang

Title(s)Professor, MIMG
SchoolMedicine
ORCID ORCID Icon0000-0001-6568-0404 Additional info
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    Collapse Biography 
    Collapse Education and Training
    California Institute of Technology, PasadenaPh.D.06/2004Biology
    Collapse Awards and Honors
    BIOS2023Top Women in Academic Entrepreneurship
    Endpoints News2022Women in Biopharm (20 women blazing trails in biopharma R&D)
    CIRM2022Quest Award
    UCLA U Magazine2021Spotlight Featured Faculty
    Department of Defense (DoD)2021Impact Award
    CIRM2021Translational Research Award
    Tower Cancer Research Foundation2020Senior Investigator Award
    UCLA2019Ablon Scholars Award
    CIRM2018Quest Award
    The American Association of Immunologist (AAI)2017Young Investigator Award
    American Society of Gene & Cell Therapy (ASGCT)2017Outstanding New Investigator (ONI) Award
    UCLA2017Life Sciences Faculty Excellence Award for Outstanding Research Publication
    Prostate Cancer Foundation (PCF)2015GTSN Challenge Award for Lethal Prostate Cancer
    Rose Hills Foundation2016RHF Research Award
    STOP CANCER Foundation2015Research Career Development Award
    CIRM2016Translational Research Award
    National Institutes of Health (NIH)2014Director's New Innovator Award (DP2)
    California Institute for Generative Medicine (CIRM)2014Exploratory Concepts Award
    Concern Foundation2014Stem Cell Research Award
    UCLA2014SPORE in Prostate Cancer Career Development Award
    UCLA2013Broad Stem Cell Research Center (BSCRC) Innovation Award
    CHARVI/HVTN2009Early Career Investigator Award
    William Guy Forbeck Research Foundation2008Forbeck Scholar Award
    MIT's Technology Review Magazine2007TR35 Award (nation's top 35 innovators under age 35)
    California Institute of Technology1999Helen G. and Arthur MmCallum Fellowship
    University of California, Riverside1997Chancellor's Distinguished Fellowship

    Collapse Overview 
    Collapse Overview
    Dr. Lili Yang is currently an Associate Professor of Microbiology, Immunology and Molecular Genetics at the University of California, Los Angeles (UCLA).

    Dr. Yang has over 20 years of experience in both basic and translational study of the immune system. Her research centers on deciphering the cellular and molecular mechanisms regulating immune responses against cancer, infection, and autoimmune diseases, and exploiting this knowledge to develop innovative immunotherapies to treat these diseases. A major strength of her research program is that it both generates scientific discoveries and translates these discoveries into clinical and commercial development. So far Dr. Yang's research has resulted in over 60 peer-reviewed publications (in prestigious journals including Nature, Nature Biotechnology, Nature Communications, Science Immunology, Cell Stem Cell, PNAS, J Exp Med, J Clin Invest, etc.), 22 patents, 2 clinical trials, and 2 biotech startups.

    The Yang Engineering Immunity Lab at UCLA has two active research directions:

    1) Identify new immune checkpoints and develop new immune checkpoint blockade (ICB) therapy for cancer.
    • New immune metabolic checkpoints (e.g., creatine).
    • New neuron/immune interface checkpoints (e.g., serotonin axis).

    2) Develop novel “off-the-shelf” allogeneic immune cell therapies for cancer.
    • Harnessing unconventional T cells: NKT, γδT, MAIT, and more.
    • Engineering stem cells: iPSC, HSC, and more.
    • Exploiting gene therapy modalities: TCR, CAR, immune enhancers, and more.
    • Targeting a broad range of cancers: blood cancers (e.g., multiple myeloma, AML), solid tumors (e.g., ovarian cancer, lung cancer, liver cancer), and more (e.g., infections and autoimmune disorders).

    Overall, the Yang Engineering Immunity Lab at UCLA has established a strong research platform that supports interdisciplinary studies spanning the areas of immunology, stem cell biology, cancer biology, infection, and gene & cell-based immunotherapy. Please visit the Lab website for details and updates: https://www.liliyanglab.com/.
    Collapse In The News

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Immune evasion in cell-based immunotherapy: unraveling challenges and novel strategies. J Biomed Sci. 2024 Jan 12; 31(1):5. Li YR, Halladay T, Yang L. PMID: 38217016; PMCID: PMC10785504.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    2. Unlocking the potential of allogeneic Vδ2 T cells for ovarian cancer therapy through CD16 biomarker selection and CAR/IL-15 engineering. Nat Commun. 2023 11 08; 14(1):6942. Lee D, Dunn ZS, Guo W, Rosenthal CJ, Penn NE, Yu Y, Zhou K, Li Z, Ma F, Li M, Song TC, Cen X, Li YR, Zhou JJ, Pellegrini M, Wang P, Yang L. PMID: 37938576; PMCID: PMC10632431.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    3. A self-assembled implantable microtubular pacemaker for wireless cardiac electrotherapy. Sci Adv. 2023 10 20; 9(42):eadj0540. Wang S, Cui Q, Abiri P, Roustaei M, Zhu E, Li YR, Wang K, Duarte S, Yang L, Ebrahimi R, Bersohn M, Chen J, Hsiai TK. PMID: 37851816; PMCID: PMC10584332.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    4. Advancements in CRISPR screens for the development of cancer immunotherapy strategies. Mol Ther Oncolytics. 2023 Dec 19; 31:100733. Li YR, Lyu Z, Tian Y, Fang Y, Zhu Y, Chen Y, Yang L. PMID: 37876793; PMCID: PMC10591018.
      View in: PubMed   Mentions:
    5. Exploring the dynamic interplay between cancer stem cells and the tumor microenvironment: implications for novel therapeutic strategies. J Transl Med. 2023 10 02; 21(1):686. Li YR, Fang Y, Lyu Z, Zhu Y, Yang L. PMID: 37784157; PMCID: PMC10546755.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    6. Profiling ovarian cancer tumor and microenvironment during disease progression for cell-based immunotherapy design. iScience. 2023 Oct 20; 26(10):107952. Li YR, Ochoa CJ, Zhu Y, Kramer A, Wilson M, Fang Y, Chen Y, Singh T, Di Bernardo G, Zhu E, Lee D, Moatamed NA, Bando J, Zhou JJ, Memarzadeh S, Yang L. PMID: 37810241; PMCID: PMC10558812.
      View in: PubMed   Mentions: 4  
    7. Bubble-Mediated Large-Scale Hierarchical Assembly of Ultrathin Pt Nanowire Network Monolayer at Gas/Liquid Interfaces. ACS Nano. 2023 Jul 25; 17(14):14152-14160. Zhu E, Liu Y, Huang J, Zhang A, Peng B, Liu Z, Liu H, Yu J, Li YR, Yang L, Duan X, Huang Y. PMID: 37410702; PMCID: PMC10373521.
      View in: PubMed   Mentions: 3     Fields:    
    8. Advancing cell-based cancer immunotherapy through stem cell engineering. Cell Stem Cell. 2023 05 04; 30(5):592-610. Li YR, Dunn ZS, Yu Y, Li M, Wang P, Yang L. PMID: 36948187; PMCID: PMC10164150.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    9. Graft-versus-Host Disease Modulation by Innate T Cells. Int J Mol Sci. 2023 Feb 17; 24(4). Fang Y, Zhu Y, Kramer A, Chen Y, Li YR, Yang L. PMID: 36835495; PMCID: PMC9962599.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    10. Mucosal-associated invariant T cells for cancer immunotherapy. Mol Ther. 2023 03 01; 31(3):631-646. Li YR, Zhou K, Wilson M, Kramer A, Zhu Y, Dawson N, Yang L. PMID: 36463401; PMCID: PMC10014234.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    11. Target tumor microenvironment by innate T cells. Front Immunol. 2022; 13:999549. Li YR, Wilson M, Yang L. PMID: 36275727; PMCID: PMC9582148.
      View in: PubMed   Mentions: 15     Fields:    
    12. Nanoformulation improves antitumor efficacy of MAOI immune checkpoint blockade therapy without causing aggression-related side effects. Front Pharmacol. 2022; 13:970324. Brown J, Li Z, Wang X, Kim YJ, Wang YC, Zuo Y, Hong W, Wang P, Li B, Yang L. PMID: 36120311; PMCID: PMC9475110.
      View in: PubMed   Mentions: 2  
    13. Off-the-shelf third-party HSC-engineered iNKT cells for ameliorating GvHD while preserving GvL effect in the treatment of blood cancers. iScience. 2022 Sep 16; 25(9):104859. Li YR, Zeng S, Dunn ZS, Zhou Y, Li Z, Yu J, Wang YC, Ku J, Cook N, Kramer A, Yang L. PMID: 36034226; PMCID: PMC9399487.
      View in: PubMed   Mentions: 13  
    14. Tumor-Localized Administration of α-GalCer to Recruit Invariant Natural Killer T Cells and Enhance Their Antitumor Activity against Solid Tumors. Int J Mol Sci. 2022 Jul 07; 23(14). Li YR, Zhou Y, Wilson M, Kramer A, Hon R, Zhu Y, Fang Y, Yang L. PMID: 35886891; PMCID: PMC9317565.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    15. Interleukin 15 in Cell-Based Cancer Immunotherapy. Int J Mol Sci. 2022 Jun 30; 23(13). Zhou Y, Husman T, Cen X, Tsao T, Brown J, Bajpai A, Li M, Zhou K, Yang L. PMID: 35806311; PMCID: PMC9266896.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    16. Human γδ T Cell Subsets and Their Clinical Applications for Cancer Immunotherapy. Cancers (Basel). 2022 Jun 18; 14(12). Lee D, Rosenthal CJ, Penn NE, Dunn ZS, Zhou Y, Yang L. PMID: 35740670; PMCID: PMC9221220.
      View in: PubMed   Mentions: 18  
    17. Targeting Immunosuppressive Tumor-Associated Macrophages Using Innate T Cells for Enhanced Antitumor Reactivity. Cancers (Basel). 2022 Jun 01; 14(11). Li YR, Brown J, Yu Y, Lee D, Zhou K, Dunn ZS, Hon R, Wilson M, Kramer A, Zhu Y, Fang Y, Yang L. PMID: 35681730; PMCID: PMC9179365.
      View in: PubMed   Mentions: 28  
    18. An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy. Cells. 2022 05 08; 11(9). Li YR, Yu Y, Kramer A, Hon R, Wilson M, Brown J, Yang L. PMID: 35563889; PMCID: PMC9101510.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    19. Engineering Induced Pluripotent Stem Cells for Cancer Immunotherapy. Cancers (Basel). 2022 May 01; 14(9). Zhou Y, Li M, Zhou K, Brown J, Tsao T, Cen X, Husman T, Bajpai A, Dunn ZS, Yang L. PMID: 35565395; PMCID: PMC9100203.
      View in: PubMed   Mentions: 23  
    20. Minimally Invasive Preclinical Monitoring of the Peritoneal Cavity Tumor Microenvironment. Cancers (Basel). 2022 Mar 31; 14(7). Dunn ZS, Li YR, Yu Y, Lee D, Gibbons A, Kim JJ, Zhou TY, Li M, Nguyen M, Cen X, Zhou Y, Wang P, Yang L. PMID: 35406547; PMCID: PMC8997523.
      View in: PubMed   Mentions: 1  
    21. Development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention. Stem Cell Res Ther. 2022 03 21; 13(1):112. Li YR, Dunn ZS, Garcia G, Carmona C, Zhou Y, Lee D, Yu J, Huang J, Kim JT, Arumugaswami V, Wang P, Yang L. PMID: 35313965; PMCID: PMC8935266.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    22. MAOI Antidepressants: Could They Be a Next-Generation ICB Therapy? Front Immunol. 2022; 13:853624. Brown J, Li B, Yang L. PMID: 35359979; PMCID: PMC8963899.
      View in: PubMed   Mentions: 3     Fields:    
    23. Development of Stem Cell-Derived Immune Cells for Off-the-Shelf Cancer Immunotherapies. Cells. 2021 12 10; 10(12). Li YR, Dunn ZS, Zhou Y, Lee D, Yang L. PMID: 34944002; PMCID: PMC8700013.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    24. HLA-A∗02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses. Cell Rep. 2021 12 28; 37(13):110167. Nesterenko PA, McLaughlin J, Tsai BL, Burton Sojo G, Cheng D, Zhao D, Mao Z, Bangayan NJ, Obusan MB, Su Y, Ng RH, Chour W, Xie J, Li YR, Lee D, Noguchi M, Carmona C, Phillips JW, Kim JT, Yang L, Heath JR, Boutros PC, Witte ON. PMID: 34919800; PMCID: PMC8660260.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    25. Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy. Cell Rep Med. 2021 11 16; 2(11):100449. Li YR, Zhou Y, Kim YJ, Zhu Y, Ma F, Yu J, Wang YC, Chen X, Li Z, Zeng S, Wang X, Lee D, Ku J, Tsao T, Hardoy C, Huang J, Cheng D, Montel-Hagen A, Seet CS, Crooks GM, Larson SM, Sasine JP, Wang X, Pellegrini M, Ribas A, Kohn DB, Witte O, Wang P, Yang L. PMID: 34841295; PMCID: PMC8607011.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    26. Engineering stem cells for cancer immunotherapy. Trends Cancer. 2021 12; 7(12):1059-1073. Li YR, Zhou Y, Kramer A, Yang L. PMID: 34479851.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    27. Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy. Nat Commun. 2021 06 10; 12(1):3530. Wang YC, Wang X, Yu J, Ma F, Li Z, Zhou Y, Zeng S, Ma X, Li YR, Neal A, Huang J, To A, Clarke N, Memarzadeh S, Pellegrini M, Yang L. PMID: 34112755; PMCID: PMC8192781.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    28. Targeting monoamine oxidase A for T cell-based cancer immunotherapy. Sci Immunol. 2021 05 14; 6(59). Wang X, Li B, Kim YJ, Wang YC, Li Z, Yu J, Zeng S, Ma X, Choi IY, Di Biase S, Smith DJ, Zhou Y, Li YR, Ma F, Huang J, Clarke N, To A, Gong L, Pham AT, Moon H, Pellegrini M, Yang L. PMID: 33990379.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    29. Creatine in T Cell Antitumor Immunity and Cancer Immunotherapy. Nutrients. 2021 May 13; 13(5). Li B, Yang L. PMID: 34067957; PMCID: PMC8152274.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    30. Methods for Studying Mouse and Human Invariant Natural Killer T Cells. Methods Mol Biol. 2021; 2388:35-57. Zhou Y, Li YR, Zeng S, Yang L. PMID: 34524660.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    31. Creatine uptake regulates CD8 T cell antitumor immunity. J Exp Med. 2019 12 02; 216(12):2869-2882. Di Biase S, Ma X, Wang X, Yu J, Wang YC, Smith DJ, Zhou Y, Li Z, Kim YJ, Clarke N, To A, Yang L. PMID: 31628186; PMCID: PMC6888972.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    32. Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. Cell Stem Cell. 2019 10 03; 25(4):542-557.e9. Zhu Y, Smith DJ, Zhou Y, Li YR, Yu J, Lee D, Wang YC, Di Biase S, Wang X, Hardoy C, Ku J, Tsao T, Lin LJ, Pham AT, Moon H, McLaughlin J, Cheng D, Hollis RP, Campo-Fernandez B, Urbinati F, Wei L, Pang L, Rezek V, Berent-Maoz B, Macabali MH, Gjertson D, Wang X, Galic Z, Kitchen SG, An DS, Hu-Lieskovan S, Kaplan-Lefko PJ, De Oliveira SN, Seet CS, Larson SM, Forman SJ, Heath JR, Zack JA, Crooks GM, Radu CG, Ribas A, Kohn DB, Witte ON, Yang L. PMID: 31495780; PMCID: PMC7018522.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    33. IND-Enabling Studies for a Clinical Trial to Genetically Program a Persistent Cancer-Targeted Immune System. Clin Cancer Res. 2019 02 01; 25(3):1000-1011. Puig-Saus C, Parisi G, Garcia-Diaz A, Krystofinski PE, Sandoval S, Zhang R, Champhekar AS, McCabe J, Cheung-Lau GC, Truong NA, Vega-Crespo A, Komenan MDS, Pang J, Macabali MH, Saco JD, Goodwin JL, Bolon B, Seet CS, Montel-Hagen A, Crooks GM, Hollis RP, Campo-Fernandez B, Bischof D, Cornetta K, Gschweng EH, Adelson C, Nguyen A, Yang L, Witte ON, Baltimore D, Comin-Anduix B, Kohn DB, Wang X, Cabrera P, Kaplan-Lefko PJ, Berent-Maoz B, Ribas A. PMID: 30409823; PMCID: PMC6359988.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    34. Isolation and characterization of NY-ESO-1-specific T cell receptors restricted on various MHC molecules. Proc Natl Acad Sci U S A. 2018 11 06; 115(45):E10702-E10711. Bethune MT, Li XH, Yu J, McLaughlin J, Cheng D, Mathis C, Moreno BH, Woods K, Knights AJ, Garcia-Diaz A, Wong S, Hu-Lieskovan S, Puig-Saus C, Cebon J, Ribas A, Yang L, Witte ON, Baltimore D. PMID: 30348802; PMCID: PMC6233129.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimals
    35. Off-the-Shelf CAR-NK Cells for Cancer Immunotherapy. Cell Stem Cell. 2018 08 02; 23(2):160-161. Siegler EL, Zhu Y, Wang P, Yang L. PMID: 30075127.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    36. Characterization of Postinfusion Phenotypic Differences in Fresh Versus Cryopreserved TCR Engineered Adoptive Cell Therapy Products. J Immunother. 2018 Jun; 41(5):248-259. Nowicki TS, Escuin-Ordinas H, Avramis E, Chmielowski B, Chodon T, Berent-Maoz B, Wang X, Kaplan-Lefko P, Yang L, Baltimore D, Economou JS, Ribas A, Comin-Anduix B. PMID: 29470191; PMCID: PMC5959255.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    37. miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity. J Clin Invest. 2017 Oct 02; 127(10):3702-3716. Li B, Wang X, Choi IY, Wang YC, Liu S, Pham AT, Moon H, Smith DJ, Rao DS, Boldin MP, Yang L. PMID: 28872459; PMCID: PMC5617680.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    38. Dendritic cell-targeted lentiviral vector immunization uses pseudotransduction and DNA-mediated STING and cGAS activation. Sci Immunol. 2017 Jul 21; 2(13). Kim JT, Liu Y, Kulkarni RP, Lee KK, Dai B, Lovely G, Ouyang Y, Wang P, Yang L, Baltimore D. PMID: 28733470; PMCID: PMC5845465.
      View in: PubMed   Mentions: 9     Fields:    
    39. Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy. Stem Cells Dev. 2016 12 15; 25(24):1863-1873. Smith DJ, Lin LJ, Moon H, Pham AT, Wang X, Liu S, Ji S, Rezek V, Shimizu S, Ruiz M, Lam J, Janzen DM, Memarzadeh S, Kohn DB, Zack JA, Kitchen SG, An DS, Yang L. PMID: 27608727; PMCID: PMC5165681.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    40. Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):1523-8. Smith DJ, Liu S, Ji S, Li B, McLaughlin J, Cheng D, Witte ON, Yang L. PMID: 25605948; PMCID: PMC4321292.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    41. Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma. Clin Cancer Res. 2014 May 01; 20(9):2457-65. Chodon T, Comin-Anduix B, Chmielowski B, Koya RC, Wu Z, Auerbach M, Ng C, Avramis E, Seja E, Villanueva A, McCannel TA, Ishiyama A, Czernin J, Radu CG, Wang X, Gjertson DW, Cochran AJ, Cornetta K, Wong DJ, Kaplan-Lefko P, Hamid O, Samlowski W, Cohen PA, Daniels GA, Mukherji B, Yang L, Zack JA, Kohn DB, Heath JR, Glaspy JA, Witte ON, Baltimore D, Economou JS, Ribas A. PMID: 24634374; PMCID: PMC4070853.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    42. Passive immunization against HIV/AIDS by antibody gene transfer. Viruses. 2014 Jan 27; 6(2):428-47. Yang L, Wang P. PMID: 24473340; PMCID: PMC3939464.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    43. Use of mutated self-cleaving 2A peptides as a molecular rheostat to direct simultaneous formation of membrane and secreted anti-HIV immunoglobulins. PLoS One. 2012; 7(11):e50438. Yu KK, Aguilar K, Tsai J, Galimidi R, Gnanapragasam P, Yang L, Baltimore D. PMID: 23209743; PMCID: PMC3508920.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    44. Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice. Blood. 2012 Nov 29; 120(23):4571-82. Hur EM, Patel SN, Shimizu S, Rao DS, Gnanapragasam PN, An DS, Yang L, Baltimore D. PMID: 23065154; PMCID: PMC3512234.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    45. miR-146a controls the resolution of T cell responses in mice. J Exp Med. 2012 Aug 27; 209(9):1655-70. Yang L, Boldin MP, Yu Y, Liu CS, Ea CK, Ramakrishnan P, Taganov KD, Zhao JL, Baltimore D. PMID: 22891274; PMCID: PMC3428948.
      View in: PubMed   Mentions: 159     Fields:    Translation:AnimalsCells
    46. A TLR4 agonist synergizes with dendritic cell-directed lentiviral vectors for inducing antigen-specific immune responses. Vaccine. 2012 Mar 28; 30(15):2570-81. Xiao L, Kim J, Lim M, Dai B, Yang L, Reed SG, Baltimore D, Wang P. PMID: 22314134; PMCID: PMC3360926.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    47. Antibody-based protection against HIV infection by vectored immunoprophylaxis. Nature. 2011 Nov 30; 481(7379):81-4. Balazs AB, Chen J, Hong CM, Rao DS, Yang L, Baltimore D. PMID: 22139420; PMCID: PMC3253190.
      View in: PubMed   Mentions: 322     Fields:    Translation:HumansAnimalsCells
    48. Homeostatic cytokines orchestrate the segregation of CD4 and CD8 memory T-cell reservoirs in mice. Blood. 2011 Sep 15; 118(11):3039-50. Yang L, Yu Y, Kalwani M, Tseng TW, Baltimore D. PMID: 21791416; PMCID: PMC3175781.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    49. miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J Exp Med. 2011 Jun 06; 208(6):1189-201. Boldin MP, Taganov KD, Rao DS, Yang L, Zhao JL, Kalwani M, Garcia-Flores Y, Luong M, Devrekanli A, Xu J, Sun G, Tay J, Linsley PS, Baltimore D. PMID: 21555486; PMCID: PMC3173243.
      View in: PubMed   Mentions: 490     Fields:    Translation:HumansAnimalsCells
    50. Dimeric 2G12 as a potent protection against HIV-1. PLoS Pathog. 2010 Dec 16; 6(12):e1001225. Luo XM, Lei MY, Feidi RA, West AP, Balazs AB, Bjorkman PJ, Yang L, Baltimore D. PMID: 21187894; PMCID: PMC3002980.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    51. Lentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populations. PLoS One. 2010 Aug 06; 5(8):e12009. O'Connell RM, Balazs AB, Rao DS, Kivork C, Yang L, Baltimore D. PMID: 20700454; PMCID: PMC2917362.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    52. Overcoming barriers to programming a therapeutic cellular immune response to fight melanoma. Pigment Cell Melanoma Res. 2010 Apr; 23(2):288-9. Baltimore D, Witte ON, Yang L, Economou J, Ribas A. PMID: 20067554.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    53. HIV-1 Gag-specific immunity induced by a lentivector-based vaccine directed to dendritic cells. Proc Natl Acad Sci U S A. 2009 Dec 01; 106(48):20382-7. Dai B, Yang L, Yang H, Hu B, Baltimore D, Wang P. PMID: 19918062; PMCID: PMC2777969.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    54. Engineering human hematopoietic stem/progenitor cells to produce a broadly neutralizing anti-HIV antibody after in vitro maturation to human B lymphocytes. Blood. 2009 Feb 12; 113(7):1422-31. Luo XM, Maarschalk E, O'Connell RM, Wang P, Yang L, Baltimore D. PMID: 19059876.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    55. Targeting lentiviral vectors to antigen-specific immunoglobulins. Hum Gene Ther. 2008 Sep; 19(9):861-72. Ziegler L, Yang L, Joo Ki, Yang H, Baltimore D, Wang P. PMID: 18590376; PMCID: PMC2599792.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    56. CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model. J Immunol. 2008 Jul 15; 181(2):1063-70. Chhabra A, Yang L, Wang P, Comin-Anduix B, Das R, Chakraborty NG, Ray S, Mehrotra S, Yang H, Hardee CL, Hollis R, Dorsky DI, Koya R, Kohn DB, Ribas A, Economou JS, Baltimore D, Mukherji B. PMID: 18606658; PMCID: PMC2715965.
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