Paul Christopher Boutros

Title(s)Professor, Human Genetics
SchoolMedicine
Address695 Charles E. Young Drive, So 6506
Los Angeles CA 90024
Phone47160
ORCID ORCID Icon0000-0003-0553-7520 Additional info
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    Other Positions
    Title(s)Professor, Urology


    Collapse Biography 
    Collapse Education and Training
    University of Toronto , CanadaExecutive MBA2016Business Administration
    University of Waterloo , CanadaB.Sc.2004Chemistry
    University of Toronto , CanadaPhD2008Medical Biophysics
    Institute of Genetics, Canadian Institutes of Health Research, Canada2017Sex and Gender in Biomedical Research Workshop
    Rotman School of Management, University of Toronto, Canada2017Rotman-UHN Leadership Training Program
    Collapse Awards and Honors
    Journal of the National Cancer Institute2019  - 2020Top 25 Peer Reviewer
    Canadian Cancer Society20182018 Bernard and Francine Dorval Prize
    European Urology2018Reviewer of the Month
    Rotman School of Management, University of Toronto2016Dean’s List & Bregman’s Scholar
    Faculty of Medicine Graduate Teaching Award, University of Toronto2016Early Career Excellence in Graduate Teaching and Mentorship
    University of Waterloo, Faculty of Science2015Young Alumni Award
    DREAM AML Prognosis Challenge Sub-Challenge 2: Remission Duration20141st Place
    DREAM AML Prognosis Challenge Sub-Challenge 3: Overall Survival Time20141st Place
    Prostate Cancer Canada2013Travel Award
    Prostate Cancer Canada2012Collaboration Exploration and Development Award
    Canadian Cancer Society Research Institute2010CCSRI Junior Investigator Grant Panel Travel Award
    The 17th International Conference on Intelligent Systems for Molecular Biology2009Travel Award
    The 11th International Meeting of the Microarray and Gene Expression Data Society2008Travel Award (declined)
    Department of Medical Biophysics Harold Johns Memorial Prize2008First Place Oral Presentation
    BioConductor Workshop 20082008Travel Award
    International Society for Computational Biology Student Council2008Travel Award
    National Cancer Institute of Canada2007Travel Award
    Canadian Cancer Society2007Travel Award
    BioVision.Nxt2007Fellow
    UHN Research Day 20062006Abstract Winner
    Canadian Institutes for Health Research / BioContact-Québec2006First Place CIHR Next Generation Award
    Canadian Institutes for Health Research / BioContact-Québec2006Travel Award
    Invitrogen Canada, Inc.2006Invitrogen Canada Young Investigator Silver Award
    Natural Sciences and Engineering Research Council2006  - 2009CGS Postgraduate Fellowship
    Excellence in Radiation Research for the 21st Century CIHR STIHR2006  - 2008CIHR Strategic Training Fellowship Alumni Award
    The Government of Ontario2006  - 2007Ontario Graduate Scholarship (declined)
    25th International Symposium on Halogenated Environmental Organic Pollutants and POPs2005Student Presenter Award
    CIHR EIRR21st Research Day2005Best Presentation Award
    Excellence in Radiation Research for the 21st Century CIHR STIHR2005  - 2007CIHR Strategic Training Fellowship (2007 declined)
    Institute for Robotics and Intelligent Systems2004PRECARN Fellowship
    15th International Symposium on Microsomes and Drug Oxidations; Mainz, Germany2004First Prize, Poster Presentations
    National Undergraduate Chemistry Conference2003First Place, Overall
    National Undergraduate Chemistry Conference2003Travel Award
    Southwestern Ontario Undergraduate Conference2003Second Place, Biochemistry Presentation
    University of Waterloo, Faculty of Science2002Dean’s Honour List
    Dow Canada Environmental Chemistry2001Work-Term Report Award

    Collapse Overview 
    Collapse Overview
    Paul Boutros, Ph.D., M.B.A., is a renowned data scientist and professor in the departments of human genetics and urology at the David Geffen School of Medicine at UCLA. He currently serves as director of the UCLA Jonsson Comprehensive Cancer Center’s Cancer Data Science program, Associate Director of cancer informatics at the UCLA Institute for Precision Health, and is a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research.

    The research in Boutros’ laboratory lies at the intersection of clinical, molecular and imaging data. He focuses on how these diverse pieces of information can be linked to personalize therapy for cancer patients. By applying techniques from modern data science strategies, particularly machine-learning, he creates biomarkers to help ensure therapies are selected that maximize cure and minimize morbidities. His work sometimes centers on specific tumor types, particularly prostate and thyroid, but often includes others in conjunction to identify general and tumor-type specific features of cancer. Some of his recent studies focus on how cancers develop differently based on the sex, age or ethnic features of the patient.

    Boutros has published over 200 peer-reviewed papers, and in his leadership roles as professor in the departments of human genetics and urology, he is currently working to support personalizing therapy for cancer by developing novel statistical methodologies. He leads the ICGC-TCGA DREAM Somatic Mutation Calling Challenge that is setting global standards for analyzing cancer genomic data, and drives programs in cancer genomics, data science and biomarker translation.

    Collapse Research 
    Collapse Research Activities and Funding
    The Influence of Germline Variation on Prostate Cancer RNA Circularization
    Prostate Cancer Foundation Sep 1, 2020 - Aug 1, 2022
    Role: PI
    Role Description: The major goal of this project is to identify if germline genomic features shape the circular RNA landscape of localized prostate cancer.
    The Evolution of Sarcoma Drug Sensitivity through Time and Space
    NIH R01CA244729Jul 1, 2020 - Jun 30, 2025
    Role: Co-Principal Investigator
    Advancing method benchmarking and data sharing through crowd-sourced competitions in cancer research
    NIH U24CA248265Jul 1, 2020 - Jun 30, 2025
    Role: Co-Principal Investigator
    Comparing the Nuclear, Mitochondrial and Microenvironmental Evolution of Adult & Pediatric Brain Cancers
    UCLA Developmental Research Program Jul 1, 2020 - Jun 1, 2021
    Role: PI
    Role Description: The major goal of this project is to investigate the evolutionary trajectories of pediatric and adult brain cancer through changes in mitochondrial numbers, hypoxia, and tumor evolution.
    Expanding the Prostate Cancer Proteome: Identity & Function of Non-Canonical ORFs
    UCLA Developmental Research Program Jul 1, 2020 - Jun 1, 2020
    Role: PI
    Role Description: The major goal of this project is to develop a database of non-canonical proteins in lethal prostate cancer and associate these proteins with clinico-molecular phenotypes.
    Characterization of Novel Molecular Signature for Accurately Predicting Prostate Cancer Progression in Active Surveillance
    The University of Calgary Feb 1, 2020 - Dec 1, 2023
    Role: Co-Investigator
    Role Description: The main goal of this project is to identify if the TMPRSS2-ERG fusion gene, PTEN genomic deletions and SPINK1 as individual or combined markers explains the metastatic potential of prostate cancer cells.
    Identification and Characterization of Oncometabolite-induced DNA Repair Defects in Sporadic Papillary Kidney Cancer
    The Hope Foundation Jan 1, 2020 - Dec 1, 2020
    Role: Co-Investigator
    Molecular Characterization and Behavior of Tumors Arising in Patients Taking 5-alpha Reductase Inhibitors
    University Health Network Nov 1, 2019 - Jul 1, 2000
    Role: PI
    PRECEPT – PRostate CancEr Prognosis and Treatment
    The University of Melbourne Jan 1, 2019 - Jan 1, 2021
    Role: Site-PI
    Role Description: The major goal of this project is to identify changes in the genomic/epigenomic/transcriptional landscape of prostate cancer that drives progression of localized disease.
    Development of Protein Biomarkers in Post-DRE Urine for use in Liquid Biopsy of Prostate Cancer
    NIH U01CA214194Sep 15, 2016 - Aug 31, 2021
    Role: Co-Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Comparative survival analysis of multiparametric tests-when molecular tests disagree-A TEAM Pathology study. NPJ Breast Cancer. 2021 Jul 08; 7(1):90. Bartlett JMS, Bayani J, Kornaga E, Xu K, Pond GR, Piper T, Mallon E, Yao CQ, Boutros PC, Hasenburg A, Dunn JA, Markopoulos C, Dirix L, Seynaeve C, van de Velde CJH, Stein RC, Rea D. PMID: 34238931.
      View in: PubMed   Mentions:
    2. Comparison of Multimodal Therapies and Outcomes Among Patients With High-Risk Prostate Cancer With Adverse Clinicopathologic Features. JAMA Netw Open. 2021 Jul 01; 4(7):e2115312. Kishan AU, Karnes RJ, Romero T, Wong JK, Motterle G, Tosoian JJ, Trock BJ, Klein EA, Stish BJ, Dess RT, Spratt DE, Pilar A, Reddy C, Levin-Epstein R, Wedde TB, Lilleby WA, Fiano R, Merrick GS, Stock RG, Demanes DJ, Moran BJ, Braccioforte M, Huland H, Tran PT, Martin S, Martínez-Monge R, Krauss DJ, Abu-Isa EI, Alam R, Schwen Z, Chang AJ, Pisansky TM, Choo R, Song DY, Greco S, Deville C, McNutt T, DeWeese TL, Ross AE, Ciezki JP, Boutros PC, Nickols NG, Bhat P, Shabsovich D, Juarez JE, Chong N, Kupelian PA, D'Amico AV, Rettig MB, Berlin A, Tward JD, Davis BJ, Reiter RE, Steinberg ML, Elashoff D, Horwitz EM, Tendulkar RD, Tilki D. PMID: 34196715.
      View in: PubMed   Mentions:    Fields:    
    3. Serological abnormalities that predict progression to systemic autoimmune rheumatic diseases in antinuclear antibody positive individuals. Rheumatology (Oxford). 2021 Jun 27. Muñoz-Grajales C, Prokopec SD, Johnson SR, Touma Z, Ahmad Z, Bonilla D, Hiraki L, Bookman A, Boutros PC, Chruscinski A, Wither J. PMID: 34175923.
      View in: PubMed   Mentions:    Fields:    
    4. A proteomic investigation of isogenic radiation resistant prostate cancer cell lines. Proteomics Clin Appl. 2021 Jun 21; e2100037. Kurganovs N, Wang H, Huang X, Ignatchenko V, Macklin A, Khan S, Downes MR, Boutros PC, Liu SK, Kislinger T. PMID: 34152685.
      View in: PubMed   Mentions:    Fields:    
    5. A community challenge to evaluate RNA-seq, fusion detection, and isoform quantification methods for cancer discovery. Cell Syst. 2021 Jun 16. Creason A, Haan D, Dang K, Chiotti KE, Inkman M, Lamb A, Yu T, Hu Y, Norman TC, Buchanan A, van Baren J, Spangler R, Rollins MR, Spellman PT, Rozanov D, Zhang J, Maher CA, Caloian C, Watson JD, Uhrig S, Haas BJ, Jain M, Akeson M, Ahsen ME, SMC-RNA Challenge Participants , Stolovitzky G, Guinney J, Boutros PC, Stuart JM, Ellrott K. PMID: 34146471.
      View in: PubMed   Mentions:    Fields:    
    6. Precision Radiotherapy: Reduction in Radiation for Oropharyngeal Cancer in the 30 ROC Trial. J Natl Cancer Inst. 2021 Jun 01; 113(6):742-751. Riaz N, Sherman E, Pei X, Schöder H, Grkovski M, Paudyal R, Katabi N, Selenica P, Yamaguchi TN, Ma D, Lee SK, Shah R, Kumar R, Kuo F, Ratnakumar A, Aleynick N, Brown D, Zhang Z, Hatzoglou V, Liu LY, Salcedo A, Tsai CJ, McBride S, Morris LGT, Boyle J, Singh B, Higginson DS, Damerla RR, Paula ADC, Price K, Moore EJ, Garcia JJ, Foote R, Ho A, Wong RJ, Chan TA, Powell SN, Boutros PC, Humm JL, Shukla-Dave A, Pfister D, Reis-Filho JS, Lee N. PMID: 33429428.
      View in: PubMed   Mentions: 4     Fields:    
    7. Aging of the progenitor cells that initiate prostate cancer. Cancer Lett. 2021 May 28; 515:28-35. Freeland J, Crowell PD, Giafaglione JM, Boutros PC, Goldstein AS. PMID: 34052326.
      View in: PubMed   Mentions:    Fields:    
    8. Copy Number Profiles of Prostate Cancer in Men of Middle Eastern Ancestry. Cancers (Basel). 2021 May 14; 13(10). Albawardi A, Livingstone J, Almarzooqi S, Palanisamy N, Houlahan KE, Awwad AAA, Abdelsalam RA, Boutros PC, Bismar TA. PMID: 34068856.
      View in: PubMed   Mentions:
    9. Patterns of Clinical Progression in Radiorecurrent High-risk Prostate Cancer. Eur Urol. 2021 May 10. Philipson RG, Romero T, Wong JK, Stish BJ, Dess RT, Spratt DE, Pilar A, Reddy C, Wedde TB, Lilleby WA, Fiano R, Merrick GS, Stock RG, Demanes DJ, Moran BJ, Braccioforte M, Tran PT, Martin S, Martinez-Monge R, Krauss DJ, Abu-Isa EI, Valle L, Chong N, Pisansky TM, Choo CR, Song DY, Greco S, Deville C, McNutt T, DeWeese TL, Ross AE, Ciezki JP, Tilki D, Karnes RJ, Klein EA, Tosoian JJ, Boutros PC, Nickols NG, Bhat P, Shabsovich D, Juarez JE, Kupelian PA, Rettig MB, Berlin A, Tward JD, Davis BJ, Reiter RE, Steinberg ML, Elashoff D, Horwitz EM, Tendulkar RD, Kishan AU. PMID: 33985797.
      View in: PubMed   Mentions:    Fields:    
    10. NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4. Sci Adv. 2021 May; 7(19). Jain P, Dvorkin-Gheva A, Mollen E, Malbeteau L, Xie M, Jessa F, Dhavarasa P, Chung S, Brown KR, Jang GH, Vora P, Notta F, Moffat J, Hedley D, Boutros PC, Wouters BG, Koritzinsky M. PMID: 33962950.
      View in: PubMed   Mentions:    Fields:    
    11. Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. Cell. 2021 Apr 15; 184(8):2239-2254.e39. Dentro SC, Leshchiner I, Haase K, Tarabichi M, Wintersinger J, Deshwar AG, Yu K, Rubanova Y, Macintyre G, Demeulemeester J, Vázquez-García I, Kleinheinz K, Livitz DG, Malikic S, Donmez N, Sengupta S, Anur P, Jolly C, Cmero M, Rosebrock D, Schumacher SE, Fan Y, Fittall M, Drews RM, Yao X, Watkins TBK, Lee J, Schlesner M, Zhu H, Adams DJ, McGranahan N, Swanton C, Getz G, Boutros PC, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Martincorena I, Markowetz F, Mustonen V, Yuan K, Gerstung M, Spellman PT, Wang W, Morris QD, Wedge DC, Van Loo P, PCAWG Evolution and Heterogeneity Working Group and the PCAWG Consortium . PMID: 33831375.
      View in: PubMed   Mentions: 3     Fields:    
    12. Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression. Sci Rep. 2021 Apr 01; 11(1):7434. Busacca S, Zhang Q, Sharkey A, Dawson AG, Moore DA, Waller DA, Nakas A, Jones C, Cain K, Luo JL, Salcedo A, Salaroglio IC, Riganti C, Le Quesne J, John T, Boutros PC, Zhang SD, Fennell DA. PMID: 33795785.
      View in: PubMed   Mentions: 1     Fields:    
    13. CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer. Nat Commun. 2021 03 19; 12(1):1781. Ahmed M, Soares F, Xia JH, Yang Y, Li J, Guo H, Su P, Tian Y, Lee HJ, Wang M, Akhtar N, Houlahan KE, Bosch A, Zhou S, Mazrooei P, Hua JT, Chen S, Petricca J, Zeng Y, Davies A, Fraser M, Quigley DA, Feng FY, Boutros PC, Lupien M, Zoubeidi A, Wang L, Walsh MJ, Wang T, Ren S, Wei GH, He HH. PMID: 33741908.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    14. All HPV-negative head and neck cancers are not the same: Analysis of the TCGA dataset reveals that anatomical sites have distinct mutation, transcriptome, hypoxia, and tumor microenvironment profiles. Oral Oncol. 2021 May; 116:105260. Kim HAJ, Zeng PYF, Shaikh MH, Mundi N, Ghasemi F, Di Gravio E, Khan H, MacNeil D, Khan MI, Patel K, Mendez A, Yoo J, Fung K, Lang P, Palma DA, Mymryk JS, Barrett JW, Boutros PC, Nichols AC. PMID: 33725617.
      View in: PubMed   Mentions:    Fields:    
    15. Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression. Nat Cell Biol. 2021 01; 23(1):87-98. Chen S, Zhu G, Yang Y, Wang F, Xiao YT, Zhang N, Bian X, Zhu Y, Yu Y, Liu F, Dong K, Mariscal J, Liu Y, Soares F, Loo Yau H, Zhang B, Chen W, Wang C, Chen D, Guo Q, Yi Z, Liu M, Fraser M, De Carvalho DD, Boutros PC, Di Vizio D, Jiang Z, van der Kwast T, Berlin A, Wu S, Wang J, He HH, Ren S. PMID: 33420488.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    16. Quantitative and Qualitative Analysis of Blood-based Liquid Biopsies to Inform Clinical Decision-making in Prostate Cancer. Eur Urol. 2021 Jun; 79(6):762-771. Casanova-Salas I, Athie A, Boutros PC, Del Re M, Miyamoto DT, Pienta KJ, Posadas EM, Sowalsky AG, Stenzl A, Wyatt AW, Mateo J. PMID: 33422353.
      View in: PubMed   Mentions: 4     Fields:    
    17. The Mutational Landscape of Metastatic Castration-sensitive Prostate Cancer: The Spectrum Theory Revisited. Eur Urol. 2021 Jan 05. Deek MP, Van der Eecken K, Phillips R, Parikh NR, Isaacsson Velho P, Lotan TL, Kishan AU, Maurer T, GAP6 Consortium , Boutros PC, Hovens C, Abramowtiz M, Pollack A, Desai N, Stish B, Feng FY, Eisenberger M, Carducci M, Pienta KJ, Markowski M, Paller CJ, Antonarakis ES, Berlin A, Ost P, Tran PT. PMID: 33419682.
      View in: PubMed   Mentions: 2     Fields:    
    18. A practical guide to cancer subclonal reconstruction from DNA sequencing. Nat Methods. 2021 02; 18(2):144-155. Tarabichi M, Salcedo A, Deshwar AG, Ni Leathlobhair M, Wintersinger J, Wedge DC, Van Loo P, Morris QD, Boutros PC. PMID: 33398189.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Analysis of the TCGA Dataset Reveals that Subsites of Laryngeal Squamous Cell Carcinoma are Molecularly Distinct. Cancers (Basel). 2020 Dec 31; 13(1). Sorgini A, Kim HAJ, Zeng PYF, Shaikh MH, Mundi N, Ghasemi F, Di Gravio E, Khan H, MacNeil D, Khan MI, Mendez A, Yoo J, Fung K, Lang P, Palma DA, Mymryk JS, Barrett JW, Patel KB, Boutros PC, Nichols AC. PMID: 33396315.
      View in: PubMed   Mentions:
    20. Quantifying the influence of mutation detection on tumour subclonal reconstruction. Nat Commun. 2020 12 07; 11(1):6247. Liu LY, Bhandari V, Salcedo A, Espiritu SMG, Morris QD, Kislinger T, Boutros PC. PMID: 33288765.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Immune-focused multi-omics analysis of prostate cancer: leukocyte Ig-Like receptors are associated with disease progression. Oncoimmunology. 2020 12 01; 9(1):1851950. Vittrant B, Bergeron A, Molina OE, Leclercq M, Légaré XP, Hovington H, Picard V, Martin-Magniette ML, Livingstone J, Boutros PC, Collins C, Fradet Y, Droit A. PMID: 33299664.
      View in: PubMed   Mentions:
    22. Author Correction: A robust benchmark for detection of germline large deletions and insertions. Nat Biotechnol. 2020 Nov; 38(11):1357. Zook JM, Hansen NF, Olson ND, Chapman L, Mullikin JC, Xiao C, Sherry S, Koren S, Phillippy AM, Boutros PC, Sahraeian SME, Huang V, Rouette A, Alexander N, Mason CE, Hajirasouliha I, Ricketts C, Lee J, Tearle R, Fiddes IT, Barrio AM, Wala J, Carroll A, Ghaffari N, Rodriguez OL, Bashir A, Jackman S, Farrell JJ, Wenger AM, Alkan C, Soylev A, Schatz MC, Garg S, Church G, Marschall T, Chen K, Fan X, English AC, Rosenfeld JA, Zhou W, Mills RE, Sage JM, Davis JR, Kaiser MD, Oliver JS, Catalano AP, Chaisson MJP, Spies N, Sedlazeck FJ, Salit M. PMID: 32699374.
      View in: PubMed   Mentions:    Fields:    
    23. TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Ka inhibition in head and neck squamous cell carcinoma. J Exp Clin Cancer Res. 2020 Oct 15; 39(1):217. Ruicci KM, Meens J, Plantinga P, Stecho W, Pinto N, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Howlett CJ, Boutros PC, Ailles L, Nichols AC. PMID: 33059733.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    24. Dose-response with stereotactic body radiotherapy for prostate cancer: A multi-institutional analysis of prostate-specific antigen kinetics and biochemical control. Radiother Oncol. 2021 01; 154:207-213. Levin-Epstein RG, Jiang NY, Wang X, Upadhyaya SK, Collins SP, Suy S, Aghdam N, Mantz C, Katz AJ, Miszczyk L, Napieralska A, Namysl-Kaletka A, Prionas N, Bagshaw H, Buyyounouski MK, Cao M, Agazaryan N, Dang A, Yuan Y, Kupelian PA, Zaorsky NG, Spratt DE, Mohamad O, Feng FY, Mahal BA, Boutros PC, Kishan AU, Juarez J, Shabsovich D, Jiang T, Kahlon S, Patel A, Patel J, Nickols NG, Steinberg ML, Fuller DB, Kishan AU. PMID: 33035622.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Flavopiridol causes cell cycle inhibition and demonstrates anti-cancer activity in anaplastic thyroid cancer models. PLoS One. 2020; 15(9):e0239315. Pinto N, Prokopec SD, Ghasemi F, Meens J, Ruicci KM, Khan IM, Mundi N, Patel K, Han MW, Yoo J, Fung K, MacNeil D, Mymryk JS, Datti A, Barrett JW, Boutros PC, Ailles L, Nichols AC. PMID: 32970704.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    26. Distinguishing Benign Renal Tumors with an Oncocytic Gene Expression (ONEX) Classifier. Eur Urol. 2021 01; 79(1):107-111. McGillivray PD, Ueno D, Pooli A, Mendhiratta N, Syed JS, Nguyen KA, Schulam PG, Humphrey PA, Adeniran AJ, Boutros PC, Shuch B. PMID: 32972793.
      View in: PubMed   Mentions:    Fields:    
    27. Systematic Assessment of Tumor Purity and Its Clinical Implications. JCO Precis Oncol. 2020; 4. Haider S, Tyekucheva S, Prandi D, Fox NS, Ahn J, Xu AW, Pantazi A, Park PJ, Laird PW, Sander C, Wang W, Demichelis F, Loda M, Boutros PC, Cancer Genome Atlas Research Network . PMID: 33015524.
      View in: PubMed   Mentions:
    28. Computational approaches to support comparative analysis of multiparametric tests: Modelling versus Training. PLoS One. 2020; 15(9):e0238593. Bartlett JMS, Bayani J, Kornaga EN, Danaher P, Crozier C, Piper T, Yao CQ, Dunn JA, Boutros PC, Stein RC, OPTIMA Trial Management Group . PMID: 32881987.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Sex differences in oncogenic mutational processes. Nat Commun. 2020 08 28; 11(1):4330. Li CH, Prokopec SD, Sun RX, Yousif F, Schmitz N, PCAWG Tumour Subtypes and Clinical Translation , Boutros PC, PCAWG Consortium . PMID: 32859912.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    30. The landscape of RNA polymerase II-associated chromatin interactions in prostate cancer. J Clin Invest. 2020 08 03; 130(8):3987-4005. Ramanand SG, Chen Y, Yuan J, Daescu K, Lambros MB, Houlahan KE, Carreira S, Yuan W, Baek G, Sharp A, Paschalis A, Kanchwala M, Gao Y, Aslam A, Safdar N, Zhan X, Raj GV, Xing C, Boutros PC, de Bono J, Zhang MQ, Mani RS. PMID: 32343676.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    31. Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics. Cell Syst. 2020 08 26; 11(2):186-195.e9. Yang M, Petralia F, Li Z, Li H, Ma W, Song X, Kim S, Lee H, Yu H, Lee B, Bae S, Heo E, Kaczmarczyk J, Stepniak P, Warchol M, Yu T, Calinawan AP, Boutros PC, Payne SH, Reva B, NCI-CPTAC-DREAM Consortium , Boja E, Rodriguez H, Stolovitzky G, Guan Y, Kang J, Wang P, Fenyö D, Saez-Rodriguez J. PMID: 32710834.
      View in: PubMed   Mentions: 2     Fields:    
    32. The DNA methylation landscape of advanced prostate cancer. Nat Genet. 2020 08; 52(8):778-789. Zhao SG, Chen WS, Li H, Foye A, Zhang M, Sjöström M, Aggarwal R, Playdle D, Liao A, Alumkal JJ, Das R, Chou J, Hua JT, Barnard TJ, Bailey AM, Chow ED, Perry MD, Dang HX, Yang R, Moussavi-Baygi R, Zhang L, Alshalalfa M, Laura Chang S, Houlahan KE, Shiah YJ, Beer TM, Thomas G, Chi KN, Gleave M, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Yvonne Kim M, Fong L, Spratt DE, Morgan TM, Bose R, Huang FW, Li H, Chesner L, Shenoy T, Goodarzi H, Asangani IA, Sandhu S, Lang JM, Mahajan NP, Lara PN, Evans CP, Febbo P, Batzoglou S, Knudsen KE, He HH, Huang J, Zwart W, Costello JF, Luo J, Tomlins SA, Wyatt AW, Dehm SM, Ashworth A, Gilbert LA, Boutros PC, Farh K, Chinnaiyan AM, Maher CA, Small EJ, Quigley DA, Feng FY. PMID: 32661416.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    33. Targeted Mass Spectrometry of a Clinically Relevant PSA Variant from Post-DRE Urines for Quantitation and Genotype Determination. Proteomics Clin Appl. 2020 11; 14(6):e2000012. Otto JJ, Correll VL, Engstroem HA, Hitefield NL, Main BP, Albracht B, Johnson-Pais T, Yang LF, Liss M, Boutros PC, Kislinger T, Leach RJ, Semmes OJ, Nyalwidhe JO. PMID: 32614141.
      View in: PubMed   Mentions: 2     Fields:    
    34. Determining the Impact of Spatial Heterogeneity on Genomic Prognostic Biomarkers for Localized Prostate Cancer. Eur Urol Oncol. 2020 Jun 27. Brastianos HC, Murgic J, Salcedo A, Chua MLK, Meng A, Fraser M, Brundage M, Fleshner NE, van der Kwast T, Bristow RG, Boutros PC, Berlin A. PMID: 32605887.
      View in: PubMed   Mentions: 1     Fields:    
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    142. A Crowdsourcing Approach to Developing and Assessing Prediction Algorithms for AML Prognosis. PLoS Comput Biol. 2016 06; 12(6):e1004890. Noren DP, Long BL, Norel R, Rrhissorrakrai K, Hess K, Hu CW, Bisberg AJ, Schultz A, Engquist E, Liu L, Lin X, Chen GM, Xie H, Hunter GA, Boutros PC, Stepanov O, DREAM 9 AML-OPC Consortium , Norman T, Friend SH, Stolovitzky G, Kornblau S, Qutub AA. PMID: 27351836.
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    155. A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials. Oncotarget. 2015 Oct 13; 6(31):31693-701. Spears M, Yousif F, Lyttle N, Boutros PC, Munro AF, Twelves C, Pritchard KI, Levine MN, Shepherd L, Bartlett JM. PMID: 26372731.
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    156. The path to routine use of genomic biomarkers in the cancer clinic. Genome Res. 2015 Oct; 25(10):1508-13. Boutros PC. PMID: 26430161.
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    157. miR-620 promotes tumor radioresistance by targeting 15-hydroxyprostaglandin dehydrogenase (HPGD). Oncotarget. 2015 Sep 08; 6(26):22439-51. Huang X, Taeb S, Jahangiri S, Korpela E, Cadonic I, Yu N, Krylov SN, Fokas E, Boutros PC, Liu SK. PMID: 26068950.
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    158. Male and female mice show significant differences in hepatic transcriptomic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. BMC Genomics. 2015 Aug 20; 16:625. Lee J, Prokopec SD, Watson JD, Sun RX, Pohjanvirta R, Boutros PC. PMID: 26290441.
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    159. Transcriptional profiling of rat white adipose tissue response to 2,3,7,8-tetrachlorodibenzo-?-dioxin. Toxicol Appl Pharmacol. 2015 Oct 15; 288(2):223-31. Houlahan KE, Prokopec SD, Sun RX, Moffat ID, Lindén J, Lensu S, Okey AB, Pohjanvirta R, Boutros PC. PMID: 26232522.
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    160. Pathway and network analysis of cancer genomes. Nat Methods. 2015 Jul; 12(7):615-621. Creixell P, Reimand J, Haider S, Wu G, Shibata T, Vazquez M, Mustonen V, Gonzalez-Perez A, Pearson J, Sander C, Raphael BJ, Marks DS, Ouellette BFF, Valencia A, Bader GD, Boutros PC, Stuart JM, Linding R, Lopez-Bigas N, Stein LD, Mutation Consequences and Pathway Analysis Working Group of the International Cancer Genome Consorti . PMID: 26125594.
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    161. Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue. Nat Genet. 2015 Jun; 47(6):689. Cooper CS, Eeles R, Wedge DC, Van Loo P, Gundem G, Alexandrov LB, Kremeyer B, Butler A, Lynch AG, Camacho N, Massie CE, Kay J, Luxton HJ, Edwards S, Kote-Jarai Z, Dennis N, Merson S, Leongamornlert D, Zamora J, Corbishley C, Thomas S, Nik-Zainal S, Ramakrishna M, O'Meara S, Matthews L, Clark J, Hurst R, Mithen R, Bristow RG, Boutros PC, Fraser M, Cooke S, Raine K, Jones D, Menzies A, Stebbings L, Hinton J, Teague J, McLaren S, Mudie L, Hardy C, Anderson E, Joseph O, Goody V, Robinson B, Maddison M, Gamble S, Greenman C, Berney D, Hazell S, Livni N, ICGC Prostate Group , Fisher C, Ogden C, Kumar P, Thompson A, Woodhouse C, Nicol D, Mayer E, Dudderidge T, Shah NC, Gnanapragasam V, Voet T, Campbell P, Futreal A, Easton D, Warren AY, Foster CS, Stratton MR, Whitaker HC, McDermott U, Brewer DS, Neal DE. PMID: 26018901.
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    163. Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection. Nat Methods. 2015 Jul; 12(7):623-30. Ewing AD, Houlahan KE, Hu Y, Ellrott K, Caloian C, Yamaguchi TN, Bare JC, P'ng C, Waggott D, Sabelnykova VY, ICGC-TCGA DREAM Somatic Mutation Calling Challenge participants , Kellen MR, Norman TC, Haussler D, Friend SH, Stolovitzky G, Margolin AA, Stuart JM, Boutros PC. PMID: 25984700.
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    164. ISOpureR: an R implementation of a computational purification algorithm of mixed tumour profiles. BMC Bioinformatics. 2015 May 14; 16:156. Anghel CV, Quon G, Haider S, Nguyen F, Deshwar AG, Morris QD, Boutros PC. PMID: 25972088.
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    165. Biomarkers and subtypes of cancer. Aging (Albany NY). 2015 May; 7(5):280-1. Starmans MH, Boutros PC. PMID: 26021974.
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    166. Matching Kidneys and Urines: Establishing Noninvasive Surrogates of Intrarenal Events in Primary Glomerulonephritis. Semin Nephrol. 2015 May; 35(3):256-65. Reich HN, Sabelnykova VY, Boutros PC. PMID: 26215863.
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    167. Developing a prognostic micro-RNA signature for human cervical carcinoma. PLoS One. 2015; 10(4):e0123946. How C, Pintilie M, Bruce JP, Hui AB, Clarke BA, Wong P, Yin S, Yan R, Waggott D, Boutros PC, Fyles A, Hedley DW, Hill RP, Milosevic M, Liu FF. PMID: 25880806.
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    168. Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers. PLoS One. 2015; 10(3):e0121872. Dodbiba L, Teichman J, Fleet A, Thai H, Starmans MH, Navab R, Chen Z, Girgis H, Eng L, Espin-Garcia O, Shen X, Bandarchi B, Schwock J, Tsao MS, El-Zimaity H, Der SD, Xu W, Bristow RG, Darling GE, Boutros PC, Ailles LE, Liu G. PMID: 25826681.
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    169. Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue. Nat Genet. 2015 Apr; 47(4):367-372. Cooper CS, Eeles R, Wedge DC, Van Loo P, Gundem G, Alexandrov LB, Kremeyer B, Butler A, Lynch AG, Camacho N, Massie CE, Kay J, Luxton HJ, Edwards S, Kote-Jarai Z, Dennis N, Merson S, Leongamornlert D, Zamora J, Corbishley C, Thomas S, Nik-Zainal S, O'Meara S, Matthews L, Clark J, Hurst R, Mithen R, Bristow RG, Boutros PC, Fraser M, Cooke S, Raine K, Jones D, Menzies A, Stebbings L, Hinton J, Teague J, McLaren S, Mudie L, Hardy C, Anderson E, Joseph O, Goody V, Robinson B, Maddison M, Gamble S, Greenman C, Berney D, Hazell S, Livni N, ICGC Prostate Group , Fisher C, Ogden C, Kumar P, Thompson A, Woodhouse C, Nicol D, Mayer E, Dudderidge T, Shah NC, Gnanapragasam V, Voet T, Campbell P, Futreal A, Easton D, Warren AY, Foster CS, Stratton MR, Whitaker HC, McDermott U, Brewer DS, Neal DE. PMID: 25730763.
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    170. Identification of a microRNA signature associated with risk of distant metastasis in nasopharyngeal carcinoma. Oncotarget. 2015 Feb 28; 6(6):4537-50. Bruce JP, Hui AB, Shi W, Perez-Ordonez B, Weinreb I, Xu W, Haibe-Kains B, Waggott DM, Boutros PC, O'Sullivan B, Waldron J, Huang SH, Chen EX, Gilbert R, Liu FF. PMID: 25738365.
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    171. Sex-related differences in murine hepatic transcriptional and proteomic responses to TCDD. Toxicol Appl Pharmacol. 2015 Apr 15; 284(2):188-96. Prokopec SD, Watson JD, Lee J, Pohjanvirta R, Boutros PC. PMID: 25703434.
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    172. A Progesterone-CXCR4 Axis Controls Mammary Progenitor Cell Fate in the Adult Gland. Stem Cell Reports. 2015 Mar 10; 4(3):313-322. Shiah YJ, Tharmapalan P, Casey AE, Joshi PA, McKee TD, Jackson HW, Beristain AG, Chan-Seng-Yue MA, Bader GD, Lydon JP, Waterhouse PD, Boutros PC, Khokha R. PMID: 28447939.
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    179. Exploiting high-throughput cell line drug screening studies to identify candidate therapeutic agents in head and neck cancer. BMC Pharmacol Toxicol. 2014 Nov 27; 15:66. Nichols AC, Black M, Yoo J, Pinto N, Fernandes A, Haibe-Kains B, Boutros PC, Barrett JW. PMID: 25428177.
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    181. Onco-proteogenomics: cancer proteomics joins forces with genomics. Nat Methods. 2014 Nov; 11(11):1107-13. Alfaro JA, Sinha A, Kislinger T, Boutros PC. PMID: 25357240.
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    182. Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER. Nat Commun. 2014 Oct 29; 5:5203. van den Beucken T, Koch E, Chu K, Rupaimoole R, Prickaerts P, Adriaens M, Voncken JW, Harris AL, Buffa FM, Haider S, Starmans MHW, Yao CQ, Ivan M, Ivan C, Pecot CV, Boutros PC, Sood AK, Koritzinsky M, Wouters BG. PMID: 25351418.
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    183. Identification of reference proteins for Western blot analyses in mouse model systems of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity. PLoS One. 2014; 9(10):e110730. Prokopec SD, Watson JD, Pohjanvirta R, Boutros PC. PMID: 25329058.
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    244. Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma. Blood. 2010 Jun 10; 115(23):4787-97. Clendening JW, Pandyra A, Li Z, Boutros PC, Martirosyan A, Lehner R, Jurisica I, Trudel S, Penn LZ. PMID: 20360469.
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    245. Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors. Cancer Cell. 2009 Dec 08; 16(6):533-46. Li M, Lee KF, Lu Y, Clarke I, Shih D, Eberhart C, Collins VP, Van Meter T, Picard D, Zhou L, Boutros PC, Modena P, Liang ML, Scherer SW, Bouffet E, Rutka JT, Pomeroy SL, Lau CC, Taylor MD, Gajjar A, Dirks PB, Hawkins CE, Huang A. PMID: 19962671.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    246. Dioxin-dependent and dioxin-independent gene batteries: comparison of liver and kidney in AHR-null mice. Toxicol Sci. 2009 Nov; 112(1):245-56. Boutros PC, Bielefeld KA, Pohjanvirta R, Harper PA. PMID: 19759094.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    247. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet. 2009 Sep 01; 18(17):3227-43. Labrie V, Fukumura R, Rastogi A, Fick LJ, Wang W, Boutros PC, Kennedy JL, Semeralul MO, Lee FH, Baker GB, Belsham DD, Barger SW, Gondo Y, Wong AH, Roder JC. PMID: 19483194.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    248. Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues. Lab Invest. 2009 May; 89(5):597-606. Hui AB, Shi W, Boutros PC, Miller N, Pintilie M, Fyles T, McCready D, Wong D, Gerster K, Waldron L, Jurisica I, Penn LZ, Liu FF. PMID: 19290006.
      View in: PubMed   Mentions: 109     Fields:    Translation:Humans
    249. Prognostic gene signatures for non-small-cell lung cancer. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2824-8. Boutros PC, Lau SK, Pintilie M, Liu N, Shepherd FA, Der SD, Tsao MS, Penn LZ, Jurisica I. PMID: 19196983.
      View in: PubMed   Mentions: 100     Fields:    Translation:Humans
    250. Optimization of experimental design parameters for high-throughput chromatin immunoprecipitation studies. Nucleic Acids Res. 2008 Dec; 36(21):e144. Ponzielli R, Boutros PC, Katz S, Stojanova A, Hanley AP, Khosravi F, Bros C, Jurisica I, Penn LZ. PMID: 18940864.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    251. Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver: comparison of rat and mouse. BMC Genomics. 2008 Sep 16; 9:419. Boutros PC, Yan R, Moffat ID, Pohjanvirta R, Okey AB. PMID: 18796159.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    252. Aryl hydrocarbon receptor-dependent induction of flavin-containing monooxygenase mRNAs in mouse liver. Drug Metab Dispos. 2008 Dec; 36(12):2499-505. Celius T, Roblin S, Harper PA, Matthews J, Boutros PC, Pohjanvirta R, Okey AB. PMID: 18765683.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    253. Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function. Cancer Res. 2008 Aug 15; 68(16):6688-97. Beheshti Zavareh R, Lau KS, Hurren R, Datti A, Ashline DJ, Gronda M, Cheung P, Simpson CD, Liu W, Wasylishen AR, Boutros PC, Shi H, Vengopal A, Jurisica I, Penn LZ, Reinhold VN, Ezzat S, Wrana J, Rose DR, Schachter H, Dennis JW, Schimmer AD. PMID: 18701493.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    254. Patterns of dioxin-altered mRNA expression in livers of dioxin-sensitive versus dioxin-resistant rats. Arch Toxicol. 2008 Nov; 82(11):809-30. Franc MA, Moffat ID, Boutros PC, Tuomisto JT, Tuomisto J, Pohjanvirta R, Okey AB. PMID: 18465118.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    255. Web-based resources for clinical bioinformatics. Methods Mol Med. 2008; 141:309-29. Joshua AM, Boutros PC. PMID: 18453097.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    256. Three-gene prognostic classifier for early-stage non small-cell lung cancer. J Clin Oncol. 2007 Dec 10; 25(35):5562-9. Lau SK, Boutros PC, Pintilie M, Blackhall FH, Zhu CQ, Strumpf D, Johnston MR, Darling G, Keshavjee S, Waddell TK, Liu N, Lau D, Penn LZ, Shepherd FA, Jurisica I, Der SD, Tsao MS. PMID: 18065728.
      View in: PubMed   Mentions: 88     Fields:    Translation:Humans
    257. CUL7 is a novel antiapoptotic oncogene. Cancer Res. 2007 Oct 15; 67(20):9616-22. Kim SS, Shago M, Kaustov L, Boutros PC, Clendening JW, Sheng Y, Trentin GA, Barsyte-Lovejoy D, Mao DY, Kay R, Jurisica I, Arrowsmith CH, Penn LZ. PMID: 17942889.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    258. Changes in gene expression induced by tienilic Acid and sulfamethoxazole: testing the danger hypothesis. J Immunotoxicol. 2007 Oct; 4(4):253-66. Pacitto SR, Uetrecht JP, Boutros PC, Popovic M. PMID: 18958736.
      View in: PubMed   Mentions: 1     Fields:    
    259. Determinants of sensitivity to lovastatin-induced apoptosis in multiple myeloma. . 2007 Jun; 6(6):1886-97. Wong WW, Clendening JW, Martirosyan A, Boutros PC, Bros C, Khosravi F, Jurisica I, Stewart AK, Bergsagel PL, Penn LZ. PMID: 17575117.
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    260. Microarray analysis of the developing cortex. J Neurobiol. 2006 Dec; 66(14):1646-58. Semeralul MO, Boutros PC, Likhodi O, Okey AB, Van Tol HH, Wong AH. PMID: 17013924.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    261. Gene expression profiling in cervical cancer: an exploration of intratumor heterogeneity. Clin Cancer Res. 2006 Oct 01; 12(19):5632-40. Bachtiary B, Boutros PC, Pintilie M, Shi W, Bastianutto C, Li JH, Schwock J, Zhang W, Penn LZ, Jurisica I, Fyles A, Liu FF. PMID: 17020965.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    262. The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis. Cancer Res. 2006 May 15; 66(10):5330-7. Barsyte-Lovejoy D, Lau SK, Boutros PC, Khosravi F, Jurisica I, Andrulis IL, Tsao MS, Penn LZ. PMID: 16707459.
      View in: PubMed   Mentions: 204     Fields:    Translation:HumansAnimalsCells
    263. Unsupervised pattern recognition: an introduction to the whys and wherefores of clustering microarray data. Brief Bioinform. 2005 Dec; 6(4):331-43. Boutros PC, Okey AB. PMID: 16420732.
      View in: PubMed   Mentions: 29     Fields:    
    264. Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol Pharmacol. 2006 Jan; 69(1):140-53. Tijet N, Boutros PC, Moffat ID, Okey AB, Tuomisto J, Pohjanvirta R. PMID: 16214954.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    265. Toxicological implications of polymorphisms in receptors for xenobiotic chemicals: the case of the aryl hydrocarbon receptor. Toxicol Appl Pharmacol. 2005 Sep 01; 207(2 Suppl):43-51. Okey AB, Franc MA, Moffat ID, Tijet N, Boutros PC, Korkalainen M, Tuomisto J, Pohjanvirta R. PMID: 15993909.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    266. Gene expression profiling in a model of D-penicillamine-induced autoimmunity in the Brown Norway rat: predictive value of early signs of danger. Chem Res Toxicol. 2005 Aug; 18(8):1193-202. Séguin B, Boutros PC, Li X, Okey AB, Uetrecht JP. PMID: 16097792.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    267. Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes. Pharmacogenet Genomics. 2005 Jun; 15(6):371-9. Okey AB, Boutros PC, Harper PA. PMID: 15900209.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    268. CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome. Nucleic Acids Res. 2005; 33(9):2952-61. Heisler LE, Torti D, Boutros PC, Watson J, Chan C, Winegarden N, Takahashi M, Yau P, Huang TH, Farnham PJ, Jurisica I, Woodgett JR, Bremner R, Penn LZ, Der SD. PMID: 15911630.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    269. Dioxin-responsive AHRE-II gene battery: identification by phylogenetic footprinting. Biochem Biophys Res Commun. 2004 Aug 27; 321(3):707-15. Boutros PC, Moffat ID, Franc MA, Tijet N, Tuomisto J, Pohjanvirta R, Okey AB. PMID: 15358164.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    270. PUNS: transcriptomic- and genomic-in silico PCR for enhanced primer design. Bioinformatics. 2004 Oct 12; 20(15):2399-400. Boutros PC, Okey AB. PMID: 15073008.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
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