Ajit S Divakaruni

Title(s)Assistant Professor, Molecular and Medical Pharmacology
SchoolMedicine
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    1. MEF2C regulates NK cell effector functions through control of lipid metabolism. Nat Immunol. 2024 Apr 08. Li JH, Zhou A, Lee CD, Shah SN, Ji JH, Senthilkumar V, Padilla ET, Ball AB, Feng Q, Bustillos CG, Riggan L, Greige A, Divakaruni AS, Annese F, Cooley-Coleman J, Skinner SA, Cowan CW, O'Sullivan TE. PMID: 38589619.
      View in: PubMed   Mentions:
    2. The metabolic cofactor Coenzyme A enhances alternative macrophage activation via MyD88-linked signaling. bioRxiv. 2024 Mar 31. Jones AE, Rios A, Ibrahimovic N, Chavez C, Bayley NA, Ball AB, Hsieh WY, Sammarco A, Bianchi AR, Cortez AA, Graeber TG, Hoffmann A, Bensinger SJ, Divakaruni AS. PMID: 38585887; PMCID: PMC10996702.
      View in: PubMed   Mentions:
    3. Crym-positive striatal astrocytes gate perseverative behaviour. Nature. 2024 Feb 28. Ollivier M, Soto JS, Linker KE, Moye SL, Jami-Alahmadi Y, Jones AE, Divakaruni AS, Kawaguchi R, Wohlschlegel JA, Khakh BS. PMID: 38418885.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis. J Biol Chem. 2024 Mar; 300(3):105702. Acevedo A, Jones AE, Danna BT, Turner R, Montales KP, Benincá C, Reue K, Shirihai OS, Stiles L, Wallace M, Wang Y, Bertholet AM, Divakaruni AS. PMID: 38301896; PMCID: PMC10910128.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Myeloid cell ACE shapes cellular metabolism and function in PCSK-9 induced atherosclerosis. Front Immunol. 2023; 14:1278383. Cao D, Saito S, Xu L, Fan W, Li X, Ahmed F, Jovanovic P, Shibata T, Che M, Bernstein EA, Gianni J, Divakaruni AS, Okwan-Duodu D, Khan Z, Riera CE, Chen F, Bernstein KE. PMID: 37928535; PMCID: PMC10623052.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer. Cell Rep. 2023 10 31; 42(10):113221. Crowell PD, Giafaglione JM, Jones AE, Nunley NM, Hashimoto T, Delcourt AML, Petcherski A, Agrawal R, Bernard MJ, Diaz JA, Heering KY, Huang RR, Low JY, Matulionis N, Navone NM, Ye H, Zoubeidi A, Christofk HR, Rettig MB, Reiter RE, Haffner MC, Boutros PC, Shirihai OS, Divakaruni AS, Goldstein AS. PMID: 37815914.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis. bioRxiv. 2023 Aug 16. Acevedo A, Jones AE, Danna BT, Turner R, Montales KP, Benincá C, Reue K, Shirihai OS, Stiles L, Wallace M, Wang Y, Bertholet AM, Divakaruni AS. PMID: 37645724; PMCID: PMC10461965.
      View in: PubMed   Mentions:
    8. Macrophage angiotensin-converting enzyme reduces atherosclerosis by increasing peroxisome proliferator-activated receptor α and fundamentally changing lipid metabolism. Cardiovasc Res. 2023 08 07; 119(9):1825-1841. Cao D, Khan Z, Li X, Saito S, Bernstein EA, Victor AR, Ahmed F, Hoshi AO, Veiras LC, Shibata T, Che M, Cai L, Temel RE, Giani JF, Luthringer DJ, Divakaruni AS, Okwan-Duodu D, Bernstein KE. PMID: 37225143; PMCID: PMC10681664.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    9. Calculation of ATP production rates using the Seahorse XF Analyzer. EMBO Rep. 2023 10 09; 24(10):e56380. Desousa BR, Kim KK, Jones AE, Ball AB, Hsieh WY, Swain P, Morrow DH, Brownstein AJ, Ferrick DA, Shirihai OS, Neilson A, Nathanson DA, Rogers GW, Dranka BP, Murphy AN, Affourtit C, Bensinger SJ, Stiles L, Romero N, Divakaruni AS. PMID: 37548091; PMCID: PMC10561364.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    10. Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome. Cell Chem Biol. 2023 07 20; 30(7):811-827.e7. Yan T, Julio AR, Villanueva M, Jones AE, Ball AB, Boatner LM, Turmon AC, Nguy?n KB, Yen SL, Desai HS, Divakaruni AS, Backus KM. PMID: 37419112; PMCID: PMC10510412.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    11. A novel approach to measure complex V ATP hydrolysis in frozen cell lysates and tissue homogenates. Life Sci Alliance. 2023 04; 6(4). Fernandez-Del-Rio L, Benincá C, Villalobos F, Shu C, Stiles L, Liesa M, Divakaruni AS, Acin-Perez R, Shirihai OS. PMID: 36918278; PMCID: PMC10019470.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    12. Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA. EMBO J. 2023 06 01; 42(11):e111901. Ngo J, Choi DW, Stanley IA, Stiles L, Molina AJA, Chen PH, Lako A, Sung ICH, Goswami R, Kim MY, Miller N, Baghdasarian S, Kim-Vasquez D, Jones AE, Roach B, Gutierrez V, Erion K, Divakaruni AS, Liesa M, Danial NN, Shirihai OS. PMID: 36917141; PMCID: PMC10233380.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    13. Proximity-labeling chemoproteomics defines the subcellular cysteinome and inflammation-responsive mitochondrial redoxome. bioRxiv. 2023 Jan 31. Yan T, Julio AR, Villanueva M, Jones AE, Ball AB, Boatner LM, Turmon AC, Yen SL, Desai HS, Divakaruni AS, Backus KM. PMID: 36711448; PMCID: PMC9882296.
      View in: PubMed   Mentions:
    14. Isolation of Mitochondria from Mouse Tissues for Functional Analysis. Methods Mol Biol. 2023; 2675:77-96. Acín-Pérez R, Montales KP, Nguyen KB, Brownstein AJ, Stiles L, Divakaruni AS. PMID: 37258757.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    15. Correction: Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium. J Biol Chem. 2022 Oct; 298(10):102493. Hazim RA, Paniagua AE, Tang L, Yang K, Kim KKO, Stiles L, Divakaruni AS, Williams DS. PMID: 36191577; PMCID: PMC9531174.
      View in: PubMed   Mentions:    Fields:    
    16. A practical guide for the analysis, standardization and interpretation of oxygen consumption measurements. Nat Metab. 2022 08; 4(8):978-994. Divakaruni AS, Jastroch M. PMID: 35971004; PMCID: PMC9618452.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    17. Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium. J Biol Chem. 2022 09; 298(9):102286. Hazim RA, Paniagua AE, Tang L, Yang K, Kim KKO, Stiles L, Divakaruni AS, Williams DS. PMID: 35868562; PMCID: PMC9396405.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    18. Amine-weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors. NMR Biomed. 2023 06; 36(6):e4785. Cho NS, Hagiwara A, Yao J, Nathanson DA, Prins RM, Wang C, Raymond C, Desousa BR, Divakaruni A, Morrow DH, Nghiemphu PL, Lai A, Liau LM, Everson RG, Salamon N, Pope WB, Cloughesy TF, Ellingson BM. PMID: 35704275.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    19. Macrophage COX2 Mediates Efferocytosis, Resolution Reprogramming, and Intestinal Epithelial Repair. Cell Mol Gastroenterol Hepatol. 2022; 13(4):1095-1120. Meriwether D, Jones AE, Ashby JW, Solorzano-Vargas RS, Dorreh N, Noori S, Grijalva V, Ball AB, Semis M, Divakaruni AS, Mack JJ, Herschman HR, Martin MG, Fogelman AM, Reddy ST. PMID: 35017061; PMCID: PMC8873959.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    20. "Aerobic glycolytic imaging" of human gliomas using combined pH-, oxygen-, and perfusion-weighted magnetic resonance imaging. Neuroimage Clin. 2021; 32:102882. Hagiwara A, Yao J, Raymond C, Cho NS, Everson R, Patel K, Morrow DH, Desousa BR, Mareninov S, Chun S, Nathanson DA, Yong WH, Andrei G, Divakaruni AS, Salamon N, Pope WB, Nghiemphu PL, Liau LM, Cloughesy TF, Ellingson BM. PMID: 34911188; PMCID: PMC8609049.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Measuring CPT-1-mediated respiration in permeabilized cells and isolated mitochondria. STAR Protoc. 2021 09 17; 2(3):100687. Yang K, Doan MT, Stiles L, Divakaruni AS. PMID: 34401773; PMCID: PMC8348308.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    22. A Single LC-MS/MS Analysis to Quantify CoA Biosynthetic Intermediates and Short-Chain Acyl CoAs. Metabolites. 2021 Jul 21; 11(8). Jones AE, Arias NJ, Acevedo A, Reddy ST, Divakaruni AS, Meriwether D. PMID: 34436409; PMCID: PMC8401288.
      View in: PubMed   Mentions: 4  
    23. Adipocytes Provide Fatty Acids to Acute Lymphoblastic Leukemia Cells. Front Oncol. 2021; 11:665763. Tucci J, Chen T, Margulis K, Orgel E, Paszkiewicz RL, Cohen MD, Oberley MJ, Wahhab R, Jones AE, Divakaruni AS, Hsu CC, Noll SE, Sheng X, Zare RN, Mittelman SD. PMID: 33968771; PMCID: PMC8100891.
      View in: PubMed   Mentions: 18  
    24. Deuterium-Stabilized (R)-Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity. Hepatol Commun. 2021 Aug; 5(8):1412-1425. Jacques V, Bolze S, Hallakou-Bozec S, Czarnik AW, Divakaruni AS, Fouqueray P, Murphy AN, Van der Ploeg LHT, DeWitt S. PMID: 34430785; PMCID: PMC8369945.
      View in: PubMed   Mentions: 13     Fields:    
    25. Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling. EMBO Rep. 2020 12 03; 21(12):e49634. Veliova M, Ferreira CM, Benador IY, Jones AE, Mahdaviani K, Brownstein AJ, Desousa BR, Acín-Pérez R, Petcherski A, Assali EA, Stiles L, Divakaruni AS, Prentki M, Corkey BE, Liesa M, Oliveira MF, Shirihai OS. PMID: 33275313; PMCID: PMC7726774.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    26. Forces, fluxes, and fuels: tracking mitochondrial metabolism by integrating measurements of membrane potential, respiration, and metabolites. Am J Physiol Cell Physiol. 2021 01 01; 320(1):C80-C91. Jones AE, Sheng L, Acevedo A, Veliova M, Shirihai OS, Stiles L, Divakaruni AS. PMID: 33147057; PMCID: PMC7846976.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    27. Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner. Cell Mol Gastroenterol Hepatol. 2021; 11(2):389-406. Chella Krishnan K, Floyd RR, Sabir S, Jayasekera DW, Leon-Mimila PV, Jones AE, Cortez AA, Shravah V, Péterfy M, Stiles L, Canizales-Quinteros S, Divakaruni AS, Huertas-Vazquez A, Lusis AJ. PMID: 32942044; PMCID: PMC7788245.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    28. Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy. iScience. 2020 Sep 25; 23(9):101453. Sperry J, Condro MC, Guo L, Braas D, Vanderveer-Harris N, Kim KKO, Pope WB, Divakaruni AS, Lai A, Christofk H, Castro MG, Lowenstein PR, Le Belle JE, Kornblum HI. PMID: 32861192; PMCID: PMC7471621.
      View in: PubMed   Mentions: 34  
    29. Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome. Cell Metab. 2020 07 07; 32(1):128-143.e5. Hsieh WY, Zhou QD, York AG, Williams KJ, Scumpia PO, Kronenberger EB, Hoi XP, Su B, Chi X, Bui VL, Khialeeva E, Kaplan A, Son YM, Divakaruni AS, Sun J, Smale ST, Flavell RA, Bensinger SJ. PMID: 32516576; PMCID: PMC7891175.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    30. A novel approach to measure mitochondrial respiration in frozen biological samples. EMBO J. 2020 07 01; 39(13):e104073. Acin-Perez R, Benador IY, Petcherski A, Veliova M, Benavides GA, Lagarrigue S, Caudal A, Vergnes L, Murphy AN, Karamanlidis G, Tian R, Reue K, Wanagat J, Sacks H, Amati F, Darley-Usmar VM, Liesa M, Divakaruni AS, Stiles L, Shirihai OS. PMID: 32432379; PMCID: PMC7327496.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    31. Macrophage activation as an archetype of mitochondrial repurposing. Mol Aspects Med. 2020 02; 71:100838. Jones AE, Divakaruni AS. PMID: 31954522; PMCID: PMC7323487.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    32. ACE overexpression in myeloid cells increases oxidative metabolism and cellular ATP. J Biol Chem. 2020 01 31; 295(5):1369-1384. Cao DY, Spivia WR, Veiras LC, Khan Z, Peng Z, Jones AE, Bernstein EA, Saito S, Okwan-Duodu D, Parker SJ, Giani JF, Divakaruni AS, Van Eyk JE, Bernstein KE. PMID: 31871049; PMCID: PMC6996878.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    33. Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury. Mol Metab. 2020 02; 32:122-135. Cordes T, Lucas A, Divakaruni AS, Murphy AN, Cabrales P, Metallo CM. PMID: 32029222; PMCID: PMC6961711.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    34. Do Two Mitochondrial Wrongs Help Make Cells Right? Trends Mol Med. 2020 01; 26(1):3-6. Divakaruni AS, Murphy AN. PMID: 31813762.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    35. Parkin does not prevent accelerated cardiac aging in mitochondrial DNA mutator mice. JCI Insight. 2019 04 16; 5. Woodall BP, Orogo AM, Najor RH, Cortez MQ, Moreno ER, Wang H, Divakaruni AS, Murphy AN, Gustafsson ÅB. PMID: 30990467; PMCID: PMC6542612.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    36. Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function. Cell Rep. 2018 12 04; 25(10):2904-2918.e8. Wortham M, Benthuysen JR, Wallace M, Savas JN, Mulas F, Divakaruni AS, Liu F, Albert V, Taylor BL, Sui Y, Saez E, Murphy AN, Yates JR, Metallo CM, Sander M. PMID: 30517875; PMCID: PMC6317899.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    37. Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span. APL Bioeng. 2018 Sep; 2(3). Sessions AO, Min P, Cordes T, Weickert BJ, Divakaruni AS, Murphy AN, Metallo CM, Engler AJ. PMID: 30105314; PMCID: PMC6086353.
      View in: PubMed   Mentions: 3  
    38. Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis. Cell Metab. 2018 09 04; 28(3):490-503.e7. Divakaruni AS, Hsieh WY, Minarrieta L, Duong TN, Kim KKO, Desousa BR, Andreyev AY, Bowman CE, Caradonna K, Dranka BP, Ferrick DA, Liesa M, Stiles L, Rogers GW, Braas D, Ciaraldi TP, Wolfgang MJ, Sparwasser T, Berod L, Bensinger SJ, Murphy AN. PMID: 30043752; PMCID: PMC6125190.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansAnimalsCells
    39. Etomoxir Actions on Regulatory and Memory T Cells Are Independent of Cpt1a-Mediated Fatty Acid Oxidation. Cell Metab. 2018 09 04; 28(3):504-515.e7. Raud B, Roy DG, Divakaruni AS, Tarasenko TN, Franke R, Ma EH, Samborska B, Hsieh WY, Wong AH, Stüve P, Arnold-Schrauf C, Guderian M, Lochner M, Rampertaap S, Romito K, Monsale J, Brönstrup M, Bensinger SJ, Murphy AN, McGuire PJ, Jones RG, Sparwasser T, Berod L. PMID: 30043753; PMCID: PMC6747686.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansAnimalsCells
    40. In situ measurements of mitochondrial matrix enzyme activities using plasma and mitochondrial membrane permeabilization agents. Anal Biochem. 2018 07 01; 552:60-65. Divakaruni AS, Andreyev AY, Rogers GW, Murphy AN. PMID: 28987935; PMCID: PMC5882612.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    41. Impaired mitophagy facilitates mitochondrial damage in Danon disease. J Mol Cell Cardiol. 2017 07; 108:86-94. Hashem SI, Murphy AN, Divakaruni AS, Klos ML, Nelson BC, Gault EC, Rowland TJ, Perry CN, Gu Y, Dalton ND, Bradford WH, Devaney EJ, Peterson KL, Jones KL, Taylor MRG, Chen J, Chi NC, Adler ED. PMID: 28526246.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    42. Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. J Cell Biol. 2017 04 03; 216(4):1091-1105. Divakaruni AS, Wallace M, Buren C, Martyniuk K, Andreyev AY, Li E, Fields JA, Cordes T, Reynolds IJ, Bloodgood BL, Raymond LA, Metallo CM, Murphy AN. PMID: 28254829; PMCID: PMC5379957.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    43. LKB1 promotes metabolic flexibility in response to energy stress. Metab Eng. 2017 09; 43(Pt B):208-217. Parker SJ, Svensson RU, Divakaruni AS, Lefebvre AE, Murphy AN, Shaw RJ, Metallo CM. PMID: 28034771; PMCID: PMC5484750.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    44. Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions. Cell Rep. 2016 08 09; 16(6):1536-1547. Zhang H, Badur MG, Divakaruni AS, Parker SJ, Jäger C, Hiller K, Murphy AN, Metallo CM. PMID: 27477285; PMCID: PMC4981511.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    45. Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes. Arthritis Rheumatol. 2016 07; 68(7):1614-26. Garcia-Carbonell R, Divakaruni AS, Lodi A, Vicente-Suarez I, Saha A, Cheroutre H, Boss GR, Tiziani S, Murphy AN, Guma M. PMID: 26815411; PMCID: PMC4963240.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    46. Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels. J Biol Chem. 2016 Jul 01; 291(27):14274-14284. Cordes T, Wallace M, Michelucci A, Divakaruni AS, Sapcariu SC, Sousa C, Koseki H, Cabrales P, Murphy AN, Hiller K, Metallo CM. PMID: 27189937; PMCID: PMC4933182.
      View in: PubMed   Mentions: 215     Fields:    Translation:AnimalsCells
    47. Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death. Sci Rep. 2016 Mar 02; 6:22538. Ding B, Parmigiani A, Divakaruni AS, Archer K, Murphy AN, Budanov AV. PMID: 26932729; PMCID: PMC4773760.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    48. HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders. Neurobiol Dis. 2016 02; 86:154-69. Fields JA, Serger E, Campos S, Divakaruni AS, Kim C, Smith K, Trejo M, Adame A, Spencer B, Rockenstein E, Murphy AN, Ellis RJ, Letendre S, Grant I, Masliah E. PMID: 26611103; PMCID: PMC4713337.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    49. Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis. Nat Chem Biol. 2016 Jan; 12(1):15-21. Green CR, Wallace M, Divakaruni AS, Phillips SA, Murphy AN, Ciaraldi TP, Metallo CM. PMID: 26571352; PMCID: PMC4684771.
      View in: PubMed   Mentions: 186     Fields:    Translation:HumansAnimalsCells
    50. GLP-1 Cleavage Product Reverses Persistent ROS Generation After Transient Hyperglycemia by Disrupting an ROS-Generating Feedback Loop. Diabetes. 2015 Sep; 64(9):3273-84. Giacco F, Du X, Carratú A, Gerfen GJ, D'Apolito M, Giardino I, Rasola A, Marin O, Divakaruni AS, Murphy AN, Shah MS, Brownlee M. PMID: 26294429; PMCID: PMC4542449.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    51. Proteomic and Metabolic Analyses of S49 Lymphoma Cells Reveal Novel Regulation of Mitochondria by cAMP and Protein Kinase A. J Biol Chem. 2015 Sep 04; 290(36):22274-86. Wilderman A, Guo Y, Divakaruni AS, Perkins G, Zhang L, Murphy AN, Taylor SS, Insel PA. PMID: 26203188; PMCID: PMC4571978.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    52. Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation. Circ Res. 2015 Feb 27; 116(5):e28-39. Westenbrink BD, Ling H, Divakaruni AS, Gray CB, Zambon AC, Dalton ND, Peterson KL, Gu Y, Matkovich SJ, Murphy AN, Miyamoto S, Dorn GW, Heller Brown J. PMID: 25605649; PMCID: PMC4344921.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    53. Regulation of substrate utilization by the mitochondrial pyruvate carrier. Mol Cell. 2014 Nov 06; 56(3):425-435. Vacanti NM, Divakaruni AS, Green CR, Parker SJ, Henry RR, Ciaraldi TP, Murphy AN, Metallo CM. PMID: 25458843; PMCID: PMC4267523.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    54. Measuring Mitochondrial Function in Permeabilized Cells Using the Seahorse XF Analyzer or a Clark-Type Oxygen Electrode. Curr Protoc Toxicol. 2014 May 27; 60:25.2.1-16. Divakaruni AS, Rogers GW, Murphy AN. PMID: 24865646.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    55. Assessment of fatty acid beta oxidation in cells and isolated mitochondria. Curr Protoc Toxicol. 2014 May 27; 60:25.3.1-19. Rogers GW, Nadanaciva S, Swiss R, Divakaruni AS, Will Y. PMID: 24865647.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    56. Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function. Int J Cardiol. 2014 Aug 01; 175(2):297-306. Yamazaki KG, Andreyev AY, Ortiz-Vilchis P, Petrosyan S, Divakaruni AS, Wiley SE, De La Fuente C, Perkins G, Ceballos G, Villarreal F, Murphy AN. PMID: 24908200; PMCID: PMC4506135.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    57. IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism. Cancer Res. 2014 Jun 15; 74(12):3317-31. Grassian AR, Parker SJ, Davidson SM, Divakaruni AS, Green CR, Zhang X, Slocum KL, Pu M, Lin F, Vickers C, Joud-Caldwell C, Chung F, Yin H, Handly ED, Straub C, Growney JD, Vander Heiden MG, Murphy AN, Pagliarini R, Metallo CM. PMID: 24755473; PMCID: PMC4885639.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansAnimalsCells
    58. Analysis and interpretation of microplate-based oxygen consumption and pH data. Methods Enzymol. 2014; 547:309-54. Divakaruni AS, Paradyse A, Ferrick DA, Murphy AN, Jastroch M. PMID: 25416364.
      View in: PubMed   Mentions: 234     Fields:    Translation:AnimalsCells
    59. Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane. Mol Metab. 2014 Apr; 3(2):114-23. Kenwood BM, Weaver JL, Bajwa A, Poon IK, Byrne FL, Murrow BA, Calderone JA, Huang L, Divakaruni AS, Tomsig JL, Okabe K, Lo RH, Cameron Coleman G, Columbus L, Yan Z, Saucerman JJ, Smith JS, Holmes JW, Lynch KR, Ravichandran KS, Uchiyama S, Santos WL, Rogers GW, Okusa MD, Bayliss DA, Hoehn KL. PMID: 24634817; PMCID: PMC3953706.
      View in: PubMed   Mentions: 114     Fields:    
    60. Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. EMBO Mol Med. 2013 Jun; 5(6):904-18. Wiley SE, Andreyev AY, Divakaruni AS, Karisch R, Perkins G, Wall EA, van der Geer P, Chen YF, Tsai TF, Simon MI, Neel BG, Dixon JE, Murphy AN. PMID: 23703906; PMCID: PMC3779451.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    61. Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. PLoS One. 2013; 8(5):e61551. Colca JR, McDonald WG, Cavey GS, Cole SL, Holewa DD, Brightwell-Conrad AS, Wolfe CL, Wheeler JS, Coulter KR, Kilkuskie PM, Gracheva E, Korshunova Y, Trusgnich M, Karr R, Wiley SE, Divakaruni AS, Murphy AN, Vigueira PA, Finck BN, Kletzien RF. PMID: 23690925; PMCID: PMC3655167.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    62. Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Proc Natl Acad Sci U S A. 2013 Apr 02; 110(14):5422-7. Divakaruni AS, Wiley SE, Rogers GW, Andreyev AY, Petrosyan S, Loviscach M, Wall EA, Yadava N, Heuck AP, Ferrick DA, Henry RR, McDonald WG, Colca JR, Simon MI, Ciaraldi TP, Murphy AN. PMID: 23513224; PMCID: PMC3619368.
      View in: PubMed   Mentions: 142     Fields:    Translation:HumansAnimalsCells
    63. Fatty acids change the conformation of uncoupling protein 1 (UCP1). J Biol Chem. 2012 Oct 26; 287(44):36845-53. Divakaruni AS, Humphrey DM, Brand MD. PMID: 22952235; PMCID: PMC3481287.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    64. Cell biology. A mitochondrial mystery, solved. Science. 2012 Jul 06; 337(6090):41-3. Divakaruni AS, Murphy AN. PMID: 22767917.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    65. The regulation and physiology of mitochondrial proton leak. Physiology (Bethesda). 2011 Jun; 26(3):192-205. Divakaruni AS, Brand MD. PMID: 21670165.
      View in: PubMed   Mentions: 188     Fields:    Translation:HumansAnimalsCells
    66. Mitochondrial uncoupling and lifespan. Mech Ageing Dev. 2010 Jul-Aug; 131(7-8):463-72. Mookerjee SA, Divakaruni AS, Jastroch M, Brand MD. PMID: 20363244; PMCID: PMC2924931.
      View in: PubMed   Mentions: 60     Fields:    
    67. The regulation and turnover of mitochondrial uncoupling proteins. Biochim Biophys Acta. 2010 Jun-Jul; 1797(6-7):785-91. Azzu V, Jastroch M, Divakaruni AS, Brand MD. PMID: 20211596; PMCID: PMC2891119.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    68. Mitochondrial proton and electron leaks. Essays Biochem. 2010; 47:53-67. Jastroch M, Divakaruni AS, Mookerjee S, Treberg JR, Brand MD. PMID: 20533900; PMCID: PMC3122475.
      View in: PubMed   Mentions: 299     Fields:    Translation:HumansAnimalsCells
    69. Real-time visualization of cytoplasmic calpain activation and calcium deregulation in acute glutamate excitotoxicity. J Neurochem. 2009 Aug; 110(3):990-1004. Gerencser AA, Mark KA, Hubbard AE, Divakaruni AS, Mehrabian Z, Nicholls DG, Polster BM. PMID: 19493161; PMCID: PMC2745075.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
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