Steven David Mittelman

Title(s)Professor, Pediatrics
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    Steven Mittelman, M.D., Ph.D., holds the Solomon A. and Marie M. Kaplan Chair of Pediatric Endocrinology.

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    Collapse Research Activities and Funding
    Sequestration and deactivation of anthracycline by adipocytes in the leukemia microenvironment
    NIH R01CA213129Aug 15, 2017 - Jul 31, 2022
    Role: Principal Investigator
    Adipocytes are Important Players in the Acute Lymphoblastic Leukemia Microenvironment
    NIH R01CA201444Jul 15, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Investigating the Role of Adipocytes on Leukemia Relapse
    NIH R01CA139060Jul 10, 2009 - May 31, 2014
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fasting-Mimicking Diet Inhibits Autophagy and Synergizes with Chemotherapy to Promote T-Cell-Dependent Leukemia-Free Survival. Cancers (Basel). 2023 Dec 16; 15(24). Buono R, Tucci J, Cutri R, Guidi N, Mangul S, Raucci F, Pellegrini M, Mittelman SD, Longo VD. PMID: 38136414; PMCID: PMC10741737.
      View in: PubMed   Mentions:
    2. Wearable Devices Beyond Activity Trackers in Youth with Obesity: Summary of Options. Child Obes. 2023 Apr 06. Chimatapu SN, Mittelman SD, Habib M, Osuna-Garcia A, Vidmar AP. PMID: 37023409.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Erratum. Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome. Diabetes 2022;71:2256-2271. Diabetes. 2023 Feb 01; 72(2):309. Yao T, Yan H, Zhu X, Zhang Q, Kong X, Guo S, Feng Y, Wang H, Hua Y, Zhang J, Mittelman SD, Tontonoz P, Zhou Z, Liu T, Kong X. PMID: 36409587; PMCID: PMC9871192.
      View in: PubMed   Mentions:    Fields:    
    4. An addiction-based digital weight loss intervention: A multi-centre randomized controlled trial. Pediatr Obes. 2023 03; 18(3):e12990. Vidmar AP, Salvy SJ, Wee CP, Pretlow R, Fox DS, Yee JK, Garell C, Glasner S, Mittelman SD. PMID: 36484235; PMCID: PMC9905275.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. From soup to nuts: Obesity impairs chemotherapy during early and late phases of acute lymphoblastic leukemia treatment. Cancer. 2023 01 01; 129(1):15-17. Orgel E, Mittelman SD. PMID: 36369919.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome. Diabetes. 2022 11 01; 71(11):2256-2271. Yao T, Yan H, Zhu X, Zhang Q, Kong X, Guo S, Feng Y, Wang H, Hua Y, Zhang J, Mittelman SD, Tontonoz P, Zhou Z, Liu T, Kong X. PMID: 35713959; PMCID: PMC9630087.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    7. Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity. J Clin Invest. 2022 08 15; 132(16). Abt ER, Rashid K, Le TM, Li S, Lee HR, Lok V, Li L, Creech AL, Labora AN, Mandl HK, Lam AK, Cho A, Rezek V, Wu N, Abril-Rodriguez G, Rosser EW, Mittelman SD, Hugo W, Mehrling T, Bantia S, Ribas A, Donahue TR, Crooks GM, Wu TT, Radu CG. PMID: 35653193; PMCID: PMC9374381.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    8. Targeting Adiposity and Inflammation With Movement to Improve Prognosis in Breast Cancer Survivors (The AIM Trial): Rationale, Design, and Methods. Front Oncol. 2022; 12:896995. Kang DW, Wilson RL, Gonzalo-Encabo P, Norris MK, Hans M, Tahbaz M, Dawson J, Nguyen D, Normann AJ, Yunker AG, Sami N, Uno H, Ligibel JA, Mittelman SD, Dieli-Conwright CM. PMID: 35795051; PMCID: PMC9251632.
      View in: PubMed   Mentions:
    9. Increased prevalence of CRLF2 rearrangements in obesity-associated acute lymphoblastic leukemia. Blood. 2021 07 15; 138(2):199-202. Mittelman SD, Kim J, Raca G, Li G, Oberley MJ, Orgel E. PMID: 33876219; PMCID: PMC8288656.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Adipocytes Provide Fatty Acids to Acute Lymphoblastic Leukemia Cells. Front Oncol. 2021; 11:665763. Tucci J, Chen T, Margulis K, Orgel E, Paszkiewicz RL, Cohen MD, Oberley MJ, Wahhab R, Jones AE, Divakaruni AS, Hsu CC, Noll SE, Sheng X, Zare RN, Mittelman SD. PMID: 33968771; PMCID: PMC8100891.
      View in: PubMed   Mentions: 18  
    11. Caloric and nutrient restriction to augment chemotherapy efficacy for acute lymphoblastic leukemia: the IDEAL trial. Blood Adv. 2021 04 13; 5(7):1853-1861. Orgel E, Framson C, Buxton R, Kim J, Li G, Tucci J, Freyer DR, Sun W, Oberley MJ, Dieli-Conwright C, Mittelman SD. PMID: 33792627; PMCID: PMC8045487.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    12. Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth. Cell Metab. 2021 05 04; 33(5):1013-1026.e6. Krall AS, Mullen PJ, Surjono F, Momcilovic M, Schmid EW, Halbrook CJ, Thambundit A, Mittelman SD, Lyssiotis CA, Shackelford DB, Knott SRV, Christofk HR. PMID: 33609439; PMCID: PMC8102379.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    13. Effect of Body Fat on Population Pharmacokinetics of High-Dose Methotrexate in Pediatric Patients With Acute Lymphoblastic Leukemia. J Clin Pharmacol. 2021 06; 61(6):755-762. Orgel E, Nabais T, Douglas C, Mittelman SD, Neely M. PMID: 33314168.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Flattening the Learning Curve: A Case-Based Video Orientation for a Subspeciality Residency Rotation. Acad Pediatr. 2021 Jan-Feb; 21(1):5-10. Shenoy RV, Mittelman SD, Relan A, Reh C, Yazdani S. PMID: 32858264.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia. Blood. 2020 07 09; 136(2):210-223. Gang EJ, Kim HN, Hsieh YT, Ruan Y, Ogana HA, Lee S, Pham J, Geng H, Park E, Klemm L, Willman CL, Carroll WL, Mittelman SD, Orgel E, Oberley MJ, Parekh C, Abdel-Azim H, Bhojwani D, Wayne AS, De Arcangelis A, Georges-Labouesse E, Wayner E, Bonig H, Minasyan A, Ten Hoeve J, Graeber TG, Müschen M, Heisterkamp N, Kim YM. PMID: 32219444; PMCID: PMC7357190.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    16. The Role of Diet in Cancer Prevention and Chemotherapy Efficacy. Annu Rev Nutr. 2020 09 23; 40:273-297. Mittelman SD. PMID: 32543948; PMCID: PMC8546934.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    17. Levocarnitine does not impair chemotherapy cytotoxicity against acute lymphoblastic leukemia. Leuk Lymphoma. 2020 02; 61(2):420-428. Sea JL, Orgel E, Chen T, Paszkiewicz RL, Krall AS, Oberley MJ, Stiles L, Mittelman SD. PMID: 31526067; PMCID: PMC7305023.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    18. Mechanisms by Which Obesity Impacts Survival from Acute Lymphoblastic Leukemia. J Natl Cancer Inst Monogr. 2019 09 01; 2019(54):152-156. Orgel E, Sea JL, Mittelman SD. PMID: 31532535; PMCID: PMC6750167.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansPHPublic Health
    19. Myosteatosis in adolescents and young adults treated for acute lymphoblastic leukemia. Leuk Lymphoma. 2019 12; 60(13):3146-3153. Mueske NM, Mittelman SD, Wren TAL, Gilsanz V, Orgel E. PMID: 31264493; PMCID: PMC6923569.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    20. Central diabetes insipidus associated with refeeding in anorexia nervosa: A case report. Int J Eat Disord. 2019 06; 52(6):752-756. Rosen EL, Thambundit A, Mehler PS, Mittelman SD. PMID: 31038775.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. Proposed endocrine funding priorities for the NICHD strategic plan: expert opinion from the Pediatric Endocrine Society. Pediatr Res. 2019 08; 86(2):141-143. Singer K, Katz ML, Mittelman SD, PES Research Affairs Committee. PMID: 30995675; PMCID: PMC6703171.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Iodine Nutrition in Weaning Infants in the United States. Thyroid. 2019 04; 29(4):573-576. Fallah R, Du L, Braverman LE, He X, Segura-Harrison M, Yeh MW, Pearce EN, Chiu HK, Mittelman SD, Leung AM. PMID: 30827204; PMCID: PMC6457884.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    23. Energy Management for Personalized Weight Reduction (EMPOWER) Program: Three-Year Outcome Data. Adv Clin Endocrinol Metab. 2019; 2(1):47-54. Vidmar AP, Fink C, Torres B, Manzanarez B, Mittelman SD, Wee CP, Borzutzky C. PMID: 32699839; PMCID: PMC7375743.
      View in: PubMed   Mentions:
    24. An addiction-based mobile health weight loss intervention: protocol of a randomized controlled trial. Contemp Clin Trials. 2019 03; 78:11-19. Vidmar AP, Salvy SJ, Pretlow R, Mittelman SD, Wee CP, Fink C, Steven Fox D, Raymond JK. PMID: 30654026; PMCID: PMC8078064.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    25. Abnormalities in autonomic function in obese boys at-risk for insulin resistance and obstructive sleep apnea. Pediatr Res. 2019 05; 85(6):790-798. Oliveira FMS, Tran WH, Lesser DJ, Bhatia R, Keens TG, Mittelman SD, Davidson Ward SL, Khoo MCK. PMID: 30420708; PMCID: PMC6494692.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Switch to low-fat diet improves outcome of acute lymphoblastic leukemia in obese mice. Cancer Metab. 2018; 6:15. Tucci J, Alhushki W, Chen T, Sheng X, Kim YM, Mittelman SD. PMID: 30410754; PMCID: PMC6211598.
      View in: PubMed   Mentions: 12  
    27. An addiction model-based mobile health weight loss intervention in adolescents with obesity. Pediatr Obes. 2019 02; 14(2):e12464. Vidmar AP, Pretlow R, Borzutzky C, Wee CP, Fox DS, Fink C, Mittelman SD. PMID: 30117309; PMCID: PMC6338524.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    28. Adipocyte metabolism of the chemotherapy daunorubicin. Oncoscience. 2018 May; 5(5-6):146-147. Mittelman SD, Orgel E. PMID: 30035170; PMCID: PMC6049316.
      View in: PubMed   Mentions: 4  
    29. Obesity and risk for venous thromboembolism from contemporary therapy for pediatric acute lymphoblastic leukemia. Thromb Res. 2018 05; 165:44-50. Prasca S, Carmona R, Ji L, Ko RH, Bhojwani D, Rawlins YA, Mittelman SD, Young G, Orgel E. PMID: 29567586; PMCID: PMC7522001.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    30. Adipose tissue inflammation in breast cancer survivors: effects of a 16-week combined aerobic and resistance exercise training intervention. Breast Cancer Res Treat. 2018 Feb; 168(1):147-157. Dieli-Conwright CM, Parmentier JH, Sami N, Lee K, Spicer D, Mack WJ, Sattler F, Mittelman SD. PMID: 29168064; PMCID: PMC6233989.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    31. Adipocytes Sequester and Metabolize the Chemotherapeutic Daunorubicin. Mol Cancer Res. 2017 12; 15(12):1704-1713. Sheng X, Parmentier JH, Tucci J, Pei H, Cortez-Toledo O, Dieli-Conwright CM, Oberley MJ, Neely M, Orgel E, Louie SG, Mittelman SD. PMID: 29117945; PMCID: PMC5726435.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    32. A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro. Sci Rep. 2017 11 03; 7(1):14479. Maggi M, Mittelman SD, Parmentier JH, Colombo G, Meli M, Whitmire JM, Merrell DS, Whitelegge J, Scotti C. PMID: 29101342; PMCID: PMC5670125.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    33. A randomized controlled trial testing an adherence-optimized Vitamin D regimen to mitigate bone change in adolescents being treated for acute lymphoblastic leukemia. Leuk Lymphoma. 2017 Oct; 58(10):2370-2378. Orgel E, Mueske NM, Sposto R, Gilsanz V, Wren TAL, Freyer DR, Butturini AM, Mittelman SD. PMID: 28278717; PMCID: PMC5489365.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    34. Adipocytes cause leukemia cell resistance to daunorubicin via oxidative stress response. Oncotarget. 2016 Nov 08; 7(45):73147-73159. Sheng X, Tucci J, Parmentier JH, Ji L, Behan JW, Heisterkamp N, Mittelman SD. PMID: 27705905; PMCID: PMC5341969.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    35. Effects of exenatide on weight and appetite in overweight adolescents and young adults with Prader-Willi syndrome. Pediatr Obes. 2017 06; 12(3):221-228. Salehi P, Hsu I, Azen CG, Mittelman SD, Geffner ME, Jeandron D. PMID: 27071367; PMCID: PMC5288290.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    36. Early injury to cortical and cancellous bone from induction chemotherapy for adolescents and young adults treated for acute lymphoblastic leukemia. Bone. 2016 Apr; 85:131-7. Orgel E, Mueske NM, Wren TA, Gilsanz V, Butturini AM, Freyer DR, Mittelman SD. PMID: 26851412; PMCID: PMC4795805.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    37. Limitations of body mass index to assess body composition due to sarcopenic obesity during leukemia therapy. Leuk Lymphoma. 2018 01; 59(1):138-145. Orgel E, Mueske NM, Sposto R, Gilsanz V, Freyer DR, Mittelman SD. PMID: 26818609; PMCID: PMC5362342.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    38. Fasting serum blood measures of bone and lipid metabolism in children with myelomeningocele for early detection of cardiovascular and bone fragility risk factors. J Spinal Cord Med. 2017 03; 40(2):193-200. Van Speybroeck A, Mueske NM, Mittelman SD, Kremer RK, Ryan DD, Wren TA. PMID: 26666357; PMCID: PMC5430477.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    39. Increased Abdominal Adiposity in Adolescents and Young Adults With Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency. J Clin Endocrinol Metab. 2015 Aug; 100(8):E1153-9. Kim MS, Ryabets-Lienhard A, Dao-Tran A, Mittelman SD, Gilsanz V, Schrager SM, Geffner ME. PMID: 26062016; PMCID: PMC4524992.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    40. Institutional adherence to cardiovascular risk factor screening guidelines for young survivors of acute lymphoblastic leukemia. J Pediatr Hematol Oncol. 2015 May; 37(4):e253-7. Lin MH, Wood JR, Mittelman SD, Freyer DR. PMID: 25757021.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    41. Glutaminase activity determines cytotoxicity of L-asparaginases on most leukemia cell lines. Leuk Res. 2015 Jul; 39(7):757-62. Parmentier JH, Maggi M, Tarasco E, Scotti C, Avramis VI, Mittelman SD. PMID: 25941002; PMCID: PMC4458142.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    42. Does near-roadway air pollution contribute to childhood obesity? Pediatr Obes. 2016 Feb; 11(1):1-3. McConnell R, Gilliland FD, Goran M, Allayee H, Hricko A, Mittelman S. PMID: 25820202; PMCID: PMC4821543.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansPHPublic Health
    43. Salsalate treatment improves glycemia without altering adipose tissue in nondiabetic obese hispanics. Obesity (Silver Spring). 2015 Mar; 23(3):543-51. Alderete TL, Sattler FR, Richey JM, Allayee H, Mittelman SD, Sheng X, Tucci J, Gyllenhammer LE, Grant EG, Goran MI. PMID: 25644856; PMCID: PMC4340767.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    44. A significant proportion of thalassemia major patients have adrenal insufficiency detectable on provocative testing. J Pediatr Hematol Oncol. 2015 Jan; 37(1):54-9. Huang KE, Mittelman SD, Coates TD, Geffner ME, Wood JC. PMID: 24942024; PMCID: PMC4393555.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    45. Effects of vitamin D repletion on glycemic control and inflammatory cytokines in adolescents with type 1 diabetes. Pediatr Diabetes. 2016 Feb; 17(1):36-43. Shih EM, Mittelman S, Pitukcheewanont P, Azen CG, Monzavi R. PMID: 25524404.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    46. Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia. Blood. 2014 Dec 18; 124(26):3932-8. Orgel E, Tucci J, Alhushki W, Malvar J, Sposto R, Fu CH, Freyer DR, Abdel-Azim H, Mittelman SD. PMID: 25349177.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    47. The role of adipose tissue and obesity in causing treatment resistance of acute lymphoblastic leukemia. Front Pediatr. 2014; 2:53. Sheng X, Mittelman SD. PMID: 24926474; PMCID: PMC4046266.
      View in: PubMed   Mentions: 25  
    48. A novel biopsy method to increase yield of subcutaneous abdominal adipose tissue. Int J Obes (Lond). 2015 Jan; 39(1):183-6. Alderete TL, Sattler FR, Sheng X, Tucci J, Mittelman SD, Grant EG, Goran MI. PMID: 24849392; PMCID: PMC5764758.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    49. Activation of adipose tissue macrophages in obese mice does not require lymphocytes. Obesity (Silver Spring). 2013 Jul; 21(7):1380-8. Behan JW, Ehsanipour EA, Sheng X, Pramanik R, Wang X, Hsieh YT, Kim YM, Mittelman SD. PMID: 23754826; PMCID: PMC3742678.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    50. Adipocyte differentiation is affected by media height above the cell layer. Int J Obes (Lond). 2014 Feb; 38(2):315-20. Sheng X, Tucci J, Malvar J, Mittelman SD. PMID: 23743593; PMCID: PMC4145870.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    51. Adipocytes cause leukemia cell resistance to L-asparaginase via release of glutamine. Cancer Res. 2013 May 15; 73(10):2998-3006. Ehsanipour EA, Sheng X, Behan JW, Wang X, Butturini A, Avramis VI, Mittelman SD. PMID: 23585457; PMCID: PMC3684066.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    52. The links between insulin resistance, diabetes, and cancer. Curr Diab Rep. 2013 Apr; 13(2):213-22. Orgel E, Mittelman SD. PMID: 23271574; PMCID: PMC3595327.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimals
    53. Adipose tissue attracts and protects acute lymphoblastic leukemia cells from chemotherapy. Leuk Res. 2013 May; 37(5):503-9. Pramanik R, Sheng X, Ichihara B, Heisterkamp N, Mittelman SD. PMID: 23332453; PMCID: PMC3622767.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    54. Sleep fragmentation and intermittent hypoxemia are associated with decreased insulin sensitivity in obese adolescent Latino males. Pediatr Res. 2012 Sep; 72(3):293-8. Lesser DJ, Bhatia R, Tran WH, Oliveira F, Ortega R, Keens TG, Mittelman SD, Khoo MC, Davidson Ward SL. PMID: 22669298; PMCID: PMC3427473.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    55. Vitamin D protects acute lymphoblastic leukemia cells from dexamethasone. Leuk Res. 2012 May; 36(5):591-3. Antony R, Sheng X, Ehsanipour EA, Ng E, Pramanik R, Klemm L, Ichihara B, Mittelman SD. PMID: 22341429; PMCID: PMC3312954.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    56. Pituitary iron and volume predict hypogonadism in transfusional iron overload. Am J Hematol. 2012 Feb; 87(2):167-71. Noetzli LJ, Panigrahy A, Mittelman SD, Hyderi A, Dongelyan A, Coates TD, Wood JC. PMID: 22213195.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    57. Pancreatic iron and glucose dysregulation in thalassemia major. Am J Hematol. 2012 Feb; 87(2):155-60. Noetzli LJ, Mittelman SD, Watanabe RM, Coates TD, Wood JC. PMID: 22120775.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    58. A longitudinal assessment of lipids in youth with type 1 diabetes. Pediatr Diabetes. 2011 Jun; 12(4 Pt 2):365-71. Reh CM, Mittelman SD, Wee CP, Shah AC, Kaufman FR, Wood JR. PMID: 21392191.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    59. Effect of gender on intra-abdominal fat in teenagers and young adults. Pediatr Radiol. 2011 Apr; 41(4):469-75. Chung SA, Dorey F, Mittelman S, Gilsanz V. PMID: 21038077.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    60. Diet-induced obesity accelerates acute lymphoblastic leukemia progression in two murine models. Cancer Prev Res (Phila). 2010 Oct; 3(10):1259-64. Yun JP, Behan JW, Heisterkamp N, Butturini A, Klemm L, Ji L, Groffen J, Müschen M, Mittelman SD. PMID: 20823291; PMCID: PMC2955776.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    61. Predicting pituitary iron and endocrine dysfunction. Ann N Y Acad Sci. 2010 Aug; 1202:123-8. Wood JC, Noetzl L, Hyderi A, Joukar M, Coates T, Mittelman S. PMID: 20712782.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    62. Obese adolescents show impaired meal responses of the appetite-regulating hormones ghrelin and PYY. Obesity (Silver Spring). 2010 May; 18(5):918-25. Mittelman SD, Klier K, Braun S, Azen C, Geffner ME, Buchanan TA. PMID: 20094039; PMCID: PMC2940837.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    63. Diet-induced obesity alters vincristine pharmacokinetics in blood and tissues of mice. Pharmacol Res. 2010 May; 61(5):385-90. Behan JW, Avramis VI, Yun JP, Louie SG, Mittelman SD. PMID: 20083201; PMCID: PMC2848885.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    64. Autonomic and metabolic effects of OSA in childhood obesity. Annu Int Conf IEEE Eng Med Biol Soc. 2010; 2010:6134-7. Oliveira FM, Tran WH, Lesser D, Bhatia R, Ortega R, Mittelman SD, Keens TG, Davidson Ward SL, Khoo MC. PMID: 21097142.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    65. Adiposity predicts carotid intima-media thickness in healthy children and adolescents. J Pediatr. 2010 Apr; 156(4):592-7.e2. Mittelman SD, Gilsanz P, Mo AO, Wood J, Dorey F, Gilsanz V. PMID: 20004913.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    66. Adipocytes impair leukemia treatment in mice. Cancer Res. 2009 Oct 01; 69(19):7867-74. Behan JW, Yun JP, Proektor MP, Ehsanipour EA, Arutyunyan A, Moses AS, Avramis VI, Louie SG, Butturini A, Heisterkamp N, Mittelman SD. PMID: 19773440; PMCID: PMC2756308.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    67. Reciprocal relations of subcutaneous and visceral fat to bone structure and strength. J Clin Endocrinol Metab. 2009 Sep; 94(9):3387-93. Gilsanz V, Chalfant J, Mo AO, Lee DC, Dorey FJ, Mittelman SD. PMID: 19531595; PMCID: PMC2741723.
      View in: PubMed   Mentions: 158     Fields:    Translation:Humans
    68. Differential effect of marrow adiposity and visceral and subcutaneous fat on cardiovascular risk in young, healthy adults. Int J Obes (Lond). 2008 Dec; 32(12):1854-60. Di Iorgi N, Mittelman SD, Gilsanz V. PMID: 18838978; PMCID: PMC2605198.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    69. Reciprocal relation between marrow adiposity and the amount of bone in the axial and appendicular skeleton of young adults. J Clin Endocrinol Metab. 2008 Jun; 93(6):2281-6. Di Iorgi N, Rosol M, Mittelman SD, Gilsanz V. PMID: 18381577; PMCID: PMC2435643.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    70. Relationship of highly sensitive C-reactive protein and lipid levels in adolescents with type 1 diabetes mellitus. Pediatr Diabetes. 2008 Apr; 9(2):122-6. Karantza MV, Mittelman SD, Dorey F, Samie S, Kaiserman K, Halvorson M, Kaufman FR. PMID: 18036131.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    71. Fat mass is not beneficial to bone in adolescents and young adults. J Clin Endocrinol Metab. 2007 Jan; 92(1):143-7. Janicka A, Wren TA, Sanchez MM, Dorey F, Kim PS, Mittelman SD, Gilsanz V. PMID: 17047019.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    72. A hypocalcemic child with a novel activating mutation of the calcium-sensing receptor gene: successful treatment with recombinant human parathyroid hormone. J Clin Endocrinol Metab. 2006 Jul; 91(7):2474-9. Mittelman SD, Hendy GN, Fefferman RA, Canaff L, Mosesova I, Cole DE, Burkett L, Geffner ME. PMID: 16608894.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    73. Obesity and fat quantification in lean tissues using three-point Dixon MR imaging. Pediatr Radiol. 2005 Jun; 35(6):601-7. Kovanlikaya A, Mittelman SD, Ward A, Geffner ME, Dorey F, Gilsanz V. PMID: 15785930.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    74. Elevated glucagon-like peptide-1-(7-36)-amide, but not glucose, associated with hyperinsulinemic compensation for fat feeding. J Clin Endocrinol Metab. 2002 Nov; 87(11):5191-8. van Citters GW, Kabir M, Kim SP, Mittelman SD, Dea MK, Brubaker PL, Bergman RN. PMID: 12414891.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    75. Extreme insulin resistance of the central adipose depot in vivo. Diabetes. 2002 Mar; 51(3):755-61. Mittelman SD, Van Citters GW, Kirkman EL, Bergman RN. PMID: 11872676.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    76. Lack of hepatic "interregulation" during inhibition of glycogenolysis in a canine model. Am J Physiol Endocrinol Metab. 2001 Aug; 281(2):E375-83. Fosgerau K, Mittelman SD, Sunehag A, Dea MK, Lundgren K, Bergman RN. PMID: 11440915.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    77. Central role of the adipocyte in the metabolic syndrome. J Investig Med. 2001 Jan; 49(1):119-26. Bergman RN, Van Citters GW, Mittelman SD, Dea MK, Hamilton-Wessler M, Kim SP, Ellmerer M. PMID: 11217141.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    78. Paradoxical effect of troglitazone in normal animals: enhancement of adipocyte but reduction of liver insulin sensitivity. Diabetes. 2000 Dec; 49(12):2087-93. Dea MK, Van Citters GW, Ader M, Mittelman SD, Sunehag AL, Bergman RN. PMID: 11118011.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    79. Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response. Diabetes. 2000 Dec; 49(12):2116-25. Mittelman SD, Van Citters GW, Kim SP, Davis DA, Dea MK, Hamilton-Wessler M, Bergman RN. PMID: 11118015.
      View in: PubMed   Mentions: 65     Fields:    Translation:Animals
    80. Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin. Am J Physiol Endocrinol Metab. 2000 Sep; 279(3):E630-7. Mittelman SD, Bergman RN. PMID: 10950832.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    81. Rapid oscillations in omental lipolysis are independent of changing insulin levels in vivo. J Clin Invest. 2000 Aug; 106(3):421-30. Getty L, Panteleon AE, Mittelman SD, Dea MK, Bergman RN. PMID: 10930445; PMCID: PMC314322.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    82. Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes. Diabetes. 2000 Mar; 49(3):399-408. Carpentier A, Mittelman SD, Bergman RN, Giacca A, Lewis GF. PMID: 10868961.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    83. Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation. Am J Physiol. 1999 06; 276(6):E1055-66. Carpentier A, Mittelman SD, Lamarche B, Bergman RN, Giacca A, Lewis GF. PMID: 10362618.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    84. Role of portal insulin delivery in the disappearance of intravenous glucose and assessment of insulin sensitivity. Diabetes. 1998 May; 47(5):714-20. Steil GM, Rebrin K, Mittelman SD, Bergman RN. PMID: 9588441.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    85. Central role of the adipocyte in insulin resistance. J Basic Clin Physiol Pharmacol. 1998; 9(2-4):205-21. Bergman RN, Mittelman SD. PMID: 10212835.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    86. Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia. J Clin Invest. 1997 Dec 15; 100(12):3121-30. Mittelman SD, Fu YY, Rebrin K, Steil G, Bergman RN. PMID: 9399959; PMCID: PMC508525.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    87. Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs. J Clin Invest. 1996 Aug 01; 98(3):741-9. Rebrin K, Steil GM, Mittelman SD, Bergman RN. PMID: 8698866; PMCID: PMC507484.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
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