Arthur K Cho

Title(s)HS Clinical Professor, Pediatrics
SchoolMedicine
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    CHEMICAL PHARMACOLOGY OF MDA AND MDMA
    NIH R01DA004206Jul 1, 1986 - Mar 31, 1994
    Role: Principal Investigator
    CHEMISTRY PHENCYCLIDINE METABOLISM
    NIH R01DA002411Aug 1, 1979 - Mar 31, 1994
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. 18F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models. J Nucl Med. 2023 01; 64(1):117-123. Le TM, Lee HR, Abt ER, Rashid K, Creech AL, Liang K, Cui J, Cho A, Wei L, Labora A, Chan C, Sanchez E, Kriti K, Karin D, Li L, Wu N, Mona C, Carlucci G, Hugo W, Wu TT, Donahue TR, Czernin J, Radu CG. PMID: 35738905; PMCID: PMC9841248.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    2. Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells. Cell Rep. 2022 01 11; 38(2):110236. Abt ER, Le TM, Dann AM, Capri JR, Poddar S, Lok V, Li L, Liang K, Creech AL, Rashid K, Kim W, Wu N, Cui J, Cho A, Lee HR, Rosser EW, Link JM, Czernin J, Wu TT, Damoiseaux R, Dawson DW, Donahue TR, Radu CG. PMID: 35021095; PMCID: PMC8893345.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    3. Combined adjuvant effects of ambient vapor-phase organic components and particulate matter potently promote allergic sensitization and Th2-skewing cytokine and chemokine milieux in mice: The importance of mechanistic multi-pollutant research. Toxicol Lett. 2022 Mar 01; 356:21-32. Li N, Lewandowski RP, Sidhu D, Holz C, Jackson-Humbles D, Eiguren-Fernandez A, Akbari P, Cho AK, Harkema JR, Froines JR, Wagner JG. PMID: 34863859.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [18F]FLT PET imaging. Proc Natl Acad Sci U S A. 2021 09 07; 118(36). Liang K, Abt ER, Le TM, Cho A, Dann AM, Cui J, Li L, Rashid K, Creech AL, Wei L, Ghukasyan R, Rosser EW, Wu N, Carlucci G, Czernin J, Donahue TR, Radu CG. PMID: 34480004; PMCID: PMC8433573.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    5. CYP2D6 genotype may moderate measures of brain structure in methamphetamine users. Addict Biol. 2021 05; 26(3):e12950. Dean AC, Nurmi EL, Morales AM, Cho AK, Seaman LC, London ED. PMID: 32767519; PMCID: PMC7865018.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism. Cell Chem Biol. 2020 02 20; 27(2):197-205.e6. Abt ER, Rosser EW, Durst MA, Lok V, Poddar S, Le TM, Cho A, Kim W, Wei L, Song J, Capri JR, Xu S, Wu N, Slavik R, Jung ME, Damoiseaux R, Czernin J, Donahue TR, Lavie A, Radu CG. PMID: 31734178; PMCID: PMC7035983.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    7. Chemical speciation, including polycyclic aromatic hydrocarbons (PAHs), and toxicity of particles emitted from meat cooking operations. Sci Total Environ. 2018 Aug 15; 633:1429-1436. Gysel N, Dixit P, Schmitz DA, Engling G, Cho AK, Cocker DR, Karavalakis G. PMID: 29758895.
      View in: PubMed   Mentions: 3     Fields:    Translation:PHPublic Health
    8. A Chemical Perspective of Pharmacology and Toxicology. Annu Rev Pharmacol Toxicol. 2018 01 06; 58:1-16. Cho AK. PMID: 29309258.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    9. Prognostic Value of Pretreatment Metabolic Tumor Volume and Total Lesion Glycolysis Using 18F-FDG PET/CT in Patients With Metastatic Renal Cell Carcinoma Treated With Anti-Vascular Endothelial Growth Factor-Targeted Agents. Clin Nucl Med. 2017 May; 42(5):e235-e241. Hwang SH, Cho A, Yun M, Choi YD, Rha SY, Kang WJ. PMID: 28288043.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    10. Impact of biodiesel on regulated and unregulated emissions, and redox and proinflammatory properties of PM emitted from heavy-duty vehicles. Sci Total Environ. 2017 Apr 15; 584-585:1230-1238. Karavalakis G, Gysel N, Schmitz DA, Cho AK, Sioutas C, Schauer JJ, Cocker DR, Durbin TD. PMID: 28148458.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    11. Trends in Tramadol: Pharmacology, Metabolism, and Misuse. Anesth Analg. 2017 01; 124(1):44-51. Miotto K, Cho AK, Khalil MA, Blanco K, Sasaki JD, Rawson R. PMID: 27861439.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimals
    12. Chemical reactivities of ambient air samples in three Southern California communities. J Air Waste Manag Assoc. 2015 Mar; 65(3):270-7. Eiguren-Fernandez A, Di Stefano E, Schmitz DA, Guarieiro AL, Salinas EM, Nasser E, Froines JR, Cho AK. PMID: 25947123; PMCID: PMC4425251.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    13. The performance of contrast-enhanced FDG PET/CT for the differential diagnosis of unexpected ovarian mass lesions in patients with nongynecologic cancer. Clin Nucl Med. 2015 Feb; 40(2):97-102. Lee JW, Lee JH, Cho A, Yun M, Lee JD, Kim YT, Kang WJ. PMID: 25546187.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    14. The additional value of attenuation correction CT acquired during 18F-FDG PET/CT in differentiating mature from immature teratomas. Clin Nucl Med. 2014 Mar; 39(3):e193-6. Cho A, Kim SW, Choi J, Kang W, Lee JD, Yun M. PMID: 23989446.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    15. Clinical and pharmacological aspects of bath salt use: a review of the literature and case reports. Drug Alcohol Depend. 2013 Sep 01; 132(1-2):1-12. Miotto K, Striebel J, Cho AK, Wang C. PMID: 23916320.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    16. Ambient vapor samples activate the Nrf2-ARE pathway in human bronchial epithelial BEAS-2B cells. Environ Toxicol. 2014 Nov; 29(11):1292-300. Shinkai Y, Nakajima S, Eiguren-Fernandez A, Di Stefano E, Schmitz DA, Froines JR, Cho AK, Kumagai Y. PMID: 23649983; PMCID: PMC4318252.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    17. Correlation between (18)f-fluorodeoxyglucose uptake and epidermal growth factor receptor mutations in advanced lung cancer. Nucl Med Mol Imaging. 2012 Sep; 46(3):169-75. Choi YJ, Cho BC, Jeong YH, Seo HJ, Kim HJ, Cho A, Lee JH, Yun M, Jeon TJ, Lee JD, Kang WJ. PMID: 24900056; PMCID: PMC4043041.
      View in: PubMed   Mentions: 14  
    18. Redox cycling of 1,2-naphthoquinone by thioredoxin1 through Cys32 and Cys35 causes inhibition of its catalytic activity and activation of ASK1/p38 signaling. Chem Res Toxicol. 2012 Jun 18; 25(6):1222-30. Shinkai Y, Iwamoto N, Miura T, Ishii T, Cho AK, Kumagai Y. PMID: 22587396.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    19. Glyceraldehyde-3-phosphate dehydrogenase as a quinone reductase in the suppression of 1,2-naphthoquinone protein adduct formation. Free Radic Biol Med. 2011 Dec 01; 51(11):2082-9. Miura T, Shinkai Y, Hirose R, Iwamoto N, Cho AK, Kumagai Y. PMID: 21963991.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    20. The chemical biology of naphthoquinones and its environmental implications. Annu Rev Pharmacol Toxicol. 2012; 52:221-47. Kumagai Y, Shinkai Y, Miura T, Cho AK. PMID: 21942631.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    21. GSH-mediated S-transarylation of a quinone glyceraldehyde-3-phosphate dehydrogenase conjugate. Chem Res Toxicol. 2011 Nov 21; 24(11):1836-44. Miura T, Kakehashi H, Shinkai Y, Egara Y, Hirose R, Cho AK, Kumagai Y. PMID: 21827172.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    22. Initial response and cellular protection through the Keap1/Nrf2 system during the exposure of primary mouse hepatocytes to 1,2-naphthoquinone. Chem Res Toxicol. 2011 Apr 18; 24(4):559-67. Miura T, Shinkai Y, Jiang HY, Iwamoto N, Sumi D, Taguchi K, Yamamoto M, Jinno H, Tanaka-Kagawa T, Cho AK, Kumagai Y. PMID: 21384861.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    23. Redox and electrophilic properties of vapor- and particle-phase components of ambient aerosols. Environ Res. 2010 Apr; 110(3):207-12. Eiguren-Fernandez A, Shinyashiki M, Schmitz DA, DiStefano E, Hinds W, Kumagai Y, Cho AK, Froines JR. PMID: 20152964; PMCID: PMC2871538.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    24. Determination of metal-based hydroxyl radical generating capacity of ambient and diesel exhaust particles. Inhal Toxicol. 2009 Aug; 21(9):731-8. DiStefano E, Eiguren-Fernandez A, Delfino RJ, Sioutas C, Froines JR, Cho AK. PMID: 19242849.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    25. Oxidative potential of semi-volatile and non volatile particulate matter (PM) from heavy-duty vehicles retrofitted with emission control technologies. Environ Sci Technol. 2009 May 15; 43(10):3905-12. Biswas S, Verma V, Schauer JJ, Cassee FR, Cho AK, Sioutas C. PMID: 19544906.
      View in: PubMed   Mentions: 25     Fields:    Translation:CellsPHPublic Health
    26. Electrophilic and redox properties of diesel exhaust particles. Environ Res. 2009 Apr; 109(3):239-44. Shinyashiki M, Eiguren-Fernandez A, Schmitz DA, Di Stefano E, Li N, Linak WP, Cho SH, Froines JR, Cho AK. PMID: 19200952.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    27. Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells. Free Radic Biol Med. 2008 Apr 15; 44(8):1645-55. Taguchi K, Shimada M, Fujii S, Sumi D, Pan X, Yamano S, Nishiyama T, Hiratsuka A, Yamamoto M, Cho AK, Froines JR, Kumagai Y. PMID: 18294972.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    28. Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative stress potential--a workshop report and consensus statement. Inhal Toxicol. 2008 Jan; 20(1):75-99. Ayres JG, Borm P, Cassee FR, Castranova V, Donaldson K, Ghio A, Harrison RM, Hider R, Kelly F, Kooter IM, Marano F, Maynard RL, Mudway I, Nel A, Sioutas C, Smith S, Baeza-Squiban A, Cho A, Duggan S, Froines J. PMID: 18236225.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimals
    29. Chemical knockdown of protein-tyrosine phosphatase 1B by 1,2-naphthoquinone through covalent modification causes persistent transactivation of epidermal growth factor receptor. J Biol Chem. 2007 Nov 16; 282(46):33396-33404. Iwamoto N, Sumi D, Ishii T, Uchida K, Cho AK, Froines JR, Kumagai Y. PMID: 17878162.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    30. Long-term methamphetamine administration in the vervet monkey models aspects of a human exposure: brain neurotoxicity and behavioral profiles. Neuropsychopharmacology. 2008 May; 33(6):1441-52. Melega WP, Jorgensen MJ, Lacan G, Way BM, Pham J, Morton G, Cho AK, Fairbanks LA. PMID: 17625500.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    31. Relationship between redox activity and chemical speciation of size-fractionated particulate matter. Part Fibre Toxicol. 2007 Jun 07; 4:5. Ntziachristos L, Froines JR, Cho AK, Sioutas C. PMID: 17555562; PMCID: PMC1899517.
      View in: PubMed   Mentions: 41     Fields:    
    32. An approach to evaluate two-electron reduction of 9,10-phenanthraquinone and redox activity of the hydroquinone associated with oxidative stress. Free Radic Biol Med. 2007 Sep 01; 43(5):789-99. Taguchi K, Fujii S, Yamano S, Cho AK, Kamisuki S, Nakai Y, Sugawara F, Froines JR, Kumagai Y. PMID: 17664142.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    33. Methamphetamine blood concentrations in human abusers: application to pharmacokinetic modeling. Synapse. 2007 Apr; 61(4):216-20. Melega WP, Cho AK, Harvey D, Lacan G. PMID: 17230548.
      View in: PubMed   Mentions: 89     Fields:    Translation:Humans
    34. Effects of naphthoquinone on airway responsiveness in the presence or absence of antigen in mice. Arch Toxicol. 2007 Aug; 81(8):575-81. Inoue K, Takano H, Ichinose T, Tomura S, Yanagisawa R, Sakurai M, Sumi D, Cho AK, Hiyoshi K, Kumagai Y. PMID: 17318628.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    35. Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge. Synapse. 2006 Nov; 60(6):465-73. O'Neil ML, Kuczenski R, Segal DS, Cho AK, Lacan G, Melega WP. PMID: 16897726.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    36. Redox activity of airborne particulate matter at different sites in the Los Angeles Basin. Environ Res. 2005 Sep; 99(1):40-7. Cho AK, Sioutas C, Miguel AH, Kumagai Y, Schmitz DA, Singh M, Eiguren-Fernandez A, Froines JR. PMID: 16053926.
      View in: PubMed   Mentions: 115     Fields:    Translation:CellsPHPublic Health
    37. Inhalation of concentrated ambient particulate matter near a heavily trafficked road stimulates antigen-induced airway responses in mice. J Air Waste Manag Assoc. 2005 Sep; 55(9):1277-88. Kleinman MT, Hamade A, Meacher D, Oldham M, Sioutas C, Chakrabarti B, Stram D, Froines JR, Cho AK. PMID: 16259423.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCellsPHPublic Health
    38. 1,2-Naphthoquinone activates vanilloid receptor 1 through increased protein tyrosine phosphorylation, leading to contraction of guinea pig trachea. Toxicol Appl Pharmacol. 2006 Jan 01; 210(1-2):47-54. Kikuno S, Taguchi K, Iwamoto N, Yamano S, Cho AK, Froines JR, Kumagai Y. PMID: 16039679.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    39. The interactions of 9,10-phenanthrenequinone with glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a potential site for toxic actions. Chem Biol Interact. 2005 Jun 30; 155(1-2):97-110. Rodriguez CE, Fukuto JM, Taguchi K, Froines J, Cho AK. PMID: 15950210.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    40. Prolonged exposure of rats to intravenous methamphetamine: behavioral and neurochemical characterization. Psychopharmacology (Berl). 2005 Jul; 180(3):501-12. Segal DS, Kuczenski R, O'Neil ML, Melega WP, Cho AK. PMID: 15959831.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    41. Effects of a single intratracheal administration of phenanthraquinone on murine lung. J Appl Toxicol. 2005 Jan-Feb; 25(1):47-51. Hiyoshi K, Takano H, Inoue K, Ichinose T, Yanagisawa R, Tomura S, Cho AK, Froines JR, Kumagai Y. PMID: 15669044.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    42. Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals. J Immunol. 2004 Sep 01; 173(5):3467-81. Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, Di Stefano E, Slaughter N, Killeen E, Wang X, Huang A, Wang M, Miguel AH, Cho A, Sioutas C, Nel AE. PMID: 15322212.
      View in: PubMed   Mentions: 168     Fields:    Translation:Cells
    43. An examination of quinone toxicity using the yeast Saccharomyces cerevisiae model system. Toxicology. 2004 Sep 01; 201(1-3):185-96. Rodriguez CE, Shinyashiki M, Froines J, Yu RC, Fukuto JM, Cho AK. PMID: 15297032.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    44. Inherent redox properties of diesel exhaust particles: catalysis of the generation of reactive oxygen species by biological reductants. Toxicol Sci. 2004 Sep; 81(1):225-32. Pan CJ, Schmitz DA, Cho AK, Froines J, Fukuto JM. PMID: 15201441.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    45. Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. Neuropsychopharmacology. 2003 Oct; 28(10):1730-40. Segal DS, Kuczenski R, O'Neil ML, Melega WP, Cho AK. PMID: 12865898.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    46. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage. Environ Health Perspect. 2003 Apr; 111(4):455-60. Li N, Sioutas C, Cho A, Schmitz D, Misra C, Sempf J, Wang M, Oberley T, Froines J, Nel A. PMID: 12676598; PMCID: PMC1241427.
      View in: PubMed   Mentions: 415     Fields:    Translation:HumansAnimalsCells
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