Jason Micheal Link

Title(s)Associate Adjunct Professor, Surgery
SchoolMedicine
ORCID ORCID Icon0000-0002-6892-0431 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. T-cell Dysfunction upon Expression of MYC with Altered Phosphorylation at Threonine 58 and Serine 62. Mol Cancer Res. 2022 07 06; 20(7):1151-1165. Daniel CJ, Pelz C, Wang X, Munks MW, Ko A, Murugan D, Byers SA, Juarez E, Taylor KL, Fan G, Coussens LM, Link JM, Sears RC. PMID: 35380701; PMCID: PMC9262837.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    2. Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells. Cell Rep. 2022 01 11; 38(2):110236. Abt ER, Le TM, Dann AM, Capri JR, Poddar S, Lok V, Li L, Liang K, Creech AL, Rashid K, Kim W, Wu N, Cui J, Cho A, Lee HR, Rosser EW, Link JM, Czernin J, Wu TT, Damoiseaux R, Dawson DW, Donahue TR, Radu CG. PMID: 35021095; PMCID: PMC8893345.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    3. High-content single-cell combinatorial indexing. Nat Biotechnol. 2021 12; 39(12):1574-1580. Mulqueen RM, Pokholok D, O'Connell BL, Thornton CA, Zhang F, O'Roak BJ, Link J, Yardimci GG, Sears RC, Steemers FJ, Adey AC. PMID: 34226710; PMCID: PMC8678206.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    4. Leukocyte Heterogeneity in Pancreatic Ductal Adenocarcinoma: Phenotypic and Spatial Features Associated with Clinical Outcome. Cancer Discov. 2021 08; 11(8):2014-2031. Liudahl SM, Betts CB, Sivagnanam S, Morales-Oyarvide V, da Silva A, Yuan C, Hwang S, Grossblatt-Wait A, Leis KR, Larson W, Lavoie MB, Robinson P, Dias Costa A, Väyrynen SA, Clancy TE, Rubinson DA, Link J, Keith D, Horton W, Tempero MA, Vonderheide RH, Jaffee EM, Sheppard B, Goecks J, Sears RC, Park BS, Mori M, Nowak JA, Wolpin BM, Coussens LM. PMID: 33727309; PMCID: PMC8338775.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    5. Tumor-Infiltrating Leukocyte Phenotypes Distinguish Outcomes in Related Patients With Pancreatic Adenocarcinoma. JCO Precis Oncol. 2021; 5. Link JM, Liudahl SM, Betts CB, Sivagnanam S, Leis KR, McDonnell M, Pelz CR, Johnson B, Hamman KJ, Keith D, Sampson JE, Morgan TK, Lopez CD, Coussens LM, Sears RC. PMID: 34036232; PMCID: PMC8140804.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer. J Exp Med. 2020 08 03; 217(8). Bhattacharyya S, Oon C, Kothari A, Horton W, Link J, Sears RC, Sherman MH. PMID: 32434218; PMCID: PMC7398167.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    7. Innate αβ T Cells Mediate Antitumor Immunity by Orchestrating Immunogenic Macrophage Programming. Cancer Discov. 2019 09; 9(9):1288-1305. Hundeyin M, Kurz E, Mishra A, Rossi JAK, Liudahl SM, Leis KR, Mehrotra H, Kim M, Torres LE, Ogunsakin A, Link J, Sears RC, Sivagnanam S, Goecks J, Islam KMS, Dolgalev I, Savadkar S, Wang W, Aykut B, Leinwand J, Diskin B, Adam S, Israr M, Gelas M, Lish J, Chin K, Farooq MS, Wadowski B, Wu J, Shah S, Adeegbe DO, Pushalkar S, Vasudevaraja V, Saxena D, Wong KK, Coussens LM, Miller G. PMID: 31266770; PMCID: PMC6726581.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    8. A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression. Cancer Discov. 2019 05; 9(5):617-627. Auciello FR, Bulusu V, Oon C, Tait-Mulder J, Berry M, Bhattacharyya S, Tumanov S, Allen-Petersen BL, Link J, Kendsersky ND, Vringer E, Schug M, Novo D, Hwang RF, Evans RM, Nixon C, Dorrell C, Morton JP, Norman JC, Sears RC, Kamphorst JJ, Sherman MH. PMID: 30837243; PMCID: PMC6497553.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    9. MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance. Nat Commun. 2017 11 23; 8(1):1728. Farrell AS, Joly MM, Allen-Petersen BL, Worth PJ, Lanciault C, Sauer D, Link J, Pelz C, Heiser LM, Morton JP, Muthalagu N, Hoffman MT, Manning SL, Pratt ED, Kendsersky ND, Egbukichi N, Amery TS, Thoma MC, Jenny ZP, Rhim AD, Murphy DJ, Sansom OJ, Crawford HC, Sheppard BC, Sears RC. PMID: 29170413; PMCID: PMC5701042.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    10. Deep learning based Nucleus Classification in pancreas histological images. Annu Int Conf IEEE Eng Med Biol Soc. 2017 Jul; 2017:672-675. Thibault G, Madin O, Azimi V, Meyers C, Johnson B, Link J, Margolin A, Gray JW. PMID: 29059962.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    11. Quantitative analysis of histological tissue image based on cytological profiles and spatial statistics. Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug; 2016:1175-1178. Thibault G, Azimi V, Johnson B, Jorgens D, Link J, Margolin A, Gray JW. PMID: 28324942.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    12. The activities of MYC, MNT and the MAX-interactome in lymphocyte proliferation and oncogenesis. Biochim Biophys Acta. 2015 May; 1849(5):554-62. Link JM, Hurlin PJ. PMID: 24731854.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    13. MYC needs MNT. Cell Cycle. 2013 Feb 01; 12(3):385-6. Link JM, Hurlin PJ. PMID: 23324353; PMCID: PMC3587433.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    14. A critical role for Mnt in Myc-driven T-cell proliferation and oncogenesis. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19685-90. Link JM, Ota S, Zhou ZQ, Daniel CJ, Sears RC, Hurlin PJ. PMID: 23150551; PMCID: PMC3511755.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    15. Measurement of the ratio of the numu charged-current single-pion production to quasielastic scattering with a 0.8 GeV neutrino beam on mineral oil. Phys Rev Lett. 2009 Aug 21; 103(8):081801. Aguilar-Arevalo AA, Anderson CE, Bazarko AO, Brice SJ, Brown BC, Bugel L, Cao J, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Garcia FG, Garvey GT, Green C, Green JA, Hart TL, Hawker E, Imlay R, Johnson RA, Karagiorgi G, Kasper P, Katori T, Kobilarcik T, Kourbanis I, Koutsoliotas S, Laird EM, Linden SK, Link JM, Liu Y, Liu Y, Louis WC, Mahn KB, Marsh W, McGary VT, McGregor G, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Nelson RH, Nienaber P, Nowak JA, Osmanov B, Ouedraogo S, Patterson RB, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smith D, Soderberg M, Sorel M, Spentzouris P, Spitz J, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Van de Water R, Wascko MO, White DH, Wilking MJ, Yang HJ, Zeller GP, Zimmerman ED, MiniBooNE Collaboration. PMID: 19792715.
      View in: PubMed   Mentions:    Fields:    
    16. Search for muon neutrino and antineutrino disappearance in MiniBooNE. Phys Rev Lett. 2009 Aug 07; 103(6):061802. Aguilar-Arevalo AA, Anderson CE, Bazarko AO, Brice SJ, Brown BC, Bugel L, Cao J, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Garcia FG, Garvey GT, Grange J, Green C, Green JA, Hart TL, Hawker E, Imlay R, Johnson RA, Karagiorgi G, Kasper P, Katori T, Kobilarcik T, Kourbanis I, Koutsoliotas S, Laird EM, Linden SK, Link JM, Liu Y, Liu Y, Louis WC, Mahn KB, Marsh W, Mauger C, McGary VT, McGregor G, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Mousseau J, Nelson RH, Nienaber P, Nowak JA, Osmanov B, Ouedraogo S, Patterson RB, Pavlovic Z, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smith D, Soderberg M, Sorel M, Spentzouris P, Spitz J, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Van de Water RG, Wascko MO, White DH, Wilking MJ, Yang HJ, Zeller GP, Zimmerman ED, MiniBooNE Collaboration. PMID: 19792551.
      View in: PubMed   Mentions:    Fields:    
    17. Measurement of numicro and nue events in an off-axis horn-focused neutrino beam. Phys Rev Lett. 2009 May 29; 102(21):211801. Adamson P, Aguilar-Arevalo AA, Anderson CE, Bazarko AO, Bishai M, Brice SJ, Brown BC, Bugel L, Cao J, Choudhary BC, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Gallagher HR, Garcia FG, Garvey GT, Green C, Green JA, Harris D, Hart TL, Hawker E, Hylen J, Imlay R, Johnson RA, Karagiorgi G, Kasper P, Katori T, Kobilarcik T, Kopp S, Kourbanis I, Koutsoliotas S, Laird EM, Linden SK, Link JM, Liu Y, Liu Y, Loiacono L, Louis WC, Marchionni A, Mahn KB, Marsh W, McGregor G, Messier MD, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Nelson JK, Nelson RH, Nguyen VT, Nienaber P, Nowak JA, Ouedraogo S, Patterson RB, Pavlovic Z, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smart W, Smith D, Sodeberg M, Sorel M, Spentzouris P, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Vahle P, Van de Water R, Viren B, Wascko MO, White DH, Wilking MJ, Yang HJ, Yumiceva FX, Zeller GP, Zimmerman ED, Zwaska R. PMID: 19519094.
      View in: PubMed   Mentions:    Fields:    
    18. The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects. Hum Mol Genet. 2009 Jul 15; 18(14):2609-21. Ota S, Zhou ZQ, Link JM, Hurlin PJ. PMID: 19403560; PMCID: PMC2701333.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    19. Unexplained excess of electronlike events from a 1-GeV neutrino beam. Phys Rev Lett. 2009 Mar 13; 102(10):101802. Aguilar-Arevalo AA, Anderson CE, Bazarko AO, Brice SJ, Brown BC, Bugel L, Cao J, Coney L, Conrad JM, Cox DC, Curioni A, Djurcic Z, Finley DA, Fleming BT, Ford R, Garcia FG, Garvey GT, Green C, Green JA, Hart TL, Hawker E, Imlay R, Johnson RA, Karagiorgi G, Kasper P, Katori T, Kobilarcik T, Kourbanis I, Koutsoliotas S, Laird EM, Linden SK, Link JM, Liu Y, Liu Y, Louis WC, Mahn KB, Marsh W, McGregor G, Metcalf W, Meyers PD, Mills F, Mills GB, Monroe J, Moore CD, Nelson RH, Nguyen VT, Nienaber P, Nowak JA, Ouedraogo S, Patterson RB, Perevalov D, Polly CC, Prebys E, Raaf JL, Ray H, Roe BP, Russell AD, Sandberg V, Schirato R, Schmitz D, Shaevitz MH, Shoemaker FC, Smith D, Sodeberg M, Sorel M, Spentzouris P, Stancu I, Stefanski RJ, Sung M, Tanaka HA, Tayloe R, Tzanov M, Van de Water R, Wascko MO, White DH, Wilking MJ, Yang HJ, Zeller GP, Zimmerman ED, MiniBooNE Collaboration. PMID: 19392103.
      View in: PubMed   Mentions:    Fields:    
    20. Monomeric DR2/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice. Clin Immunol. 2007 Apr; 123(1):95-104. Link JM, Rich CM, Korat M, Burrows GG, Offner H, Vandenbark AA. PMID: 17257899.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsPHPublic Health
    21. AlphaB-crystallin-reactive T cells from knockout mice are not encephalitogenic. J Neuroimmunol. 2006 Jul; 176(1-2):51-62. Wang C, Chou YK, Rich CM, Link JM, Afentoulis ME, van Noort JM, Wawrousek EF, Offner H, Vandenbark AA. PMID: 16844233.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    22. Identification of HLA-DRB1*1501-restricted T-cell epitopes from prostate-specific antigen. Clin Cancer Res. 2005 Apr 15; 11(8):2853-61. Klyushnenkova EN, Link J, Oberle WT, Kodak J, Rich C, Vandenbark AA, Alexander RB. PMID: 15837732.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    23. Despite extensive similarity in germline DH and JH sequence, the adult Rhesus macaque CDR-H3 repertoire differs from human. Mol Immunol. 2005 May; 42(8):943-55. Link JM, Larson JE, Schroeder HW. PMID: 15829286.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    24. Adult lupus-prone MRL/MpJ2+ mice express a primary antibody repertoire that differs in CDR-H3 length distribution and hydrophobicity from that expressed in the C3H parental strain. Mol Immunol. 2005 May; 42(7):789-98. Zemlin M, Ippolito GC, Zemlin C, Link J, Monestier M, Schroeder HW. PMID: 15829267.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    25. Rationally designed mutations convert complexes of human recombinant T cell receptor ligands into monomers that retain biological activity. J Chem Technol Biotechnol. 2005 Jan; 80(1):2-12. Huan JY, Meza-Romero R, Mooney JL, Chou YK, Edwards DM, Rich C, Link JM, Vandenbark AA, Bourdette DN, Bächinger HP, Burrows GG. PMID: 22973070; PMCID: PMC3438139.
      View in: PubMed   Mentions: 10     Fields:    
    26. HLA-DRB1*1501 risk association in multiple sclerosis may not be related to presentation of myelin epitopes. J Neurosci Res. 2004 Oct 01; 78(1):100-14. Finn TP, Jones RE, Rich C, Dahan R, Link J, David CS, Chou YK, Offner H, Vandenbark AA. PMID: 15372502.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    27. T-cell hybridoma specific for myelin oligodendrocyte glycoprotein-35-55 peptide produced from HLA-DRB1*1501-transgenic mice. J Neurosci Res. 2004 Sep 01; 77(5):670-80. Chou YK, Culbertson N, Rich C, LaTocha D, Buenafe AC, Huan J, Link J, Wands JM, Born WK, Offner H, Bourdette DN, Burrows GG, Vandenbark AA. PMID: 15352213.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    28. Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. Eur J Immunol. 2004 May; 34(5):1251-61. Rich C, Link JM, Zamora A, Jacobsen H, Meza-Romero R, Offner H, Jones R, Burrows GG, Fugger L, Vandenbark AA. PMID: 15114658.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    29. Monomeric recombinant TCR ligand reduces relapse rate and severity of experimental autoimmune encephalomyelitis in SJL/J mice through cytokine switch. J Immunol. 2004 Apr 01; 172(7):4556-66. Huan J, Subramanian S, Jones R, Rich C, Link J, Mooney J, Bourdette DN, Vandenbark AA, Burrows GG, Offner H. PMID: 15034073.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    30. Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures. J Mol Biol. 2003 Dec 05; 334(4):733-49. Zemlin M, Klinger M, Link J, Zemlin C, Bauer K, Engler JA, Schroeder HW, Kirkham PM. PMID: 14636599.
      View in: PubMed   Mentions: 135     Fields:    Translation:HumansAnimalsCells
    31. The Rhesus monkey immunoglobulin IGHD and IGHJ germline repertoire. Immunogenetics. 2002 Jul; 54(4):240-50. Link JM, Hellinger MA, Schroeder HW. PMID: 12136335.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    32. Clues to the etiology of autoimmune diseases through analysis of immunoglobulin genes. Arthritis Res. 2002; 4(2):80-3. Link JM, Schroeder HW. PMID: 11879542; PMCID: PMC128918.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    33. Cardiac receptor physiology and its application to clinical imaging: present and future. J Nucl Cardiol. 2001 May-Jun; 8(3):390-409. Tseng H, Link JM, Stratton JR, Caldwell JH. PMID: 11391310.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans