Timothy R Donahue

Title(s)Professor, Surgery
SchoolMedicine
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    Other Positions
    Title(s)Professor, Molecular and Medical Pharmacology


    Collapse Overview 
    Collapse Overview
    Dr. Timothy Donahue holds the Garry Shandling Chair in Pancreatic Surgery. He is also the Director of the UCLA Agi Hirshberg Center for Pancreatic Diseases.

    Collapse Research 
    Collapse Research Activities and Funding
    Targeting KRAS and adenosine mediated immunosuppression in pancreatic cancer
    NIH R01CA260678Mar 1, 2021 - Feb 28, 2026
    Role: Co-Principal Investigator
    Leveraging Vulnerabilities Induced by STING Activation in Pancreatic Cancer
    NIH R01CA250529Feb 15, 2021 - Jan 31, 2026
    Role: Principal Investigator
    UCLA Multifunctional Mesoporous Silica Nanoparticle Platform for Treatment of Pancreas Cancer
    NIH U01CA198846Sep 25, 2015 - Jul 31, 2021
    Role: Co-Principal Investigator
    PET Imaging-guided Personalized Therapy in Pancreatic Cancer
    NIH R01CA187678Aug 18, 2014 - Jul 31, 2020
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Carnitine palmitoyltransferase 1B mediates gemcitabine resistance in pancreatic cancer. Surgery. 2024 Mar 25. Srienc MK, Donahue TR. PMID: 38527919.
      View in: PubMed   Mentions:    Fields:    
    2. Clinical and pathological factors associated with survival in patients with pancreatic cancer who receive adjuvant therapy after neoadjuvant therapy: A retrospective multi-institutional analysis. Surgery. 2024 May; 175(5):1377-1385. Shimizu T, Maeda S, Link J, Deranteriassian A, Premji A, Verma A, Chervu N, Park J, Girgis M, Benharash P, Hines J, Wainberg Z, Wolfgang C, Burns W, Yu J, Fernandez-Del Castillo C, Lillemoe K, Ferrone C, Donahue T. PMID: 38365548.
      View in: PubMed   Mentions:    Fields:    
    3. ASO Author Reflections: Unlocking the Value of Inpatient Palliative Care for Patients with Pancreatic Cancer. Ann Surg Oncol. 2024 Feb; 31(2):1362-1363. Kim S, Chervu N, Premji A, Mallick S, Verma A, Ali K, Benharash P, Donahue T. PMID: 38063981.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Development of a Novel CLDN18.2-directed Monoclonal Antibody and Antibody-Drug Conjugate for Treatment of CLDN18.2-Positive Cancers. Mol Cancer Ther. 2023 Dec 01; 22(12):1365-1375. O'Brien NA, McDermott MSJ, Zhang J, Gong KW, Lu M, Hoffstrom B, Luo T, Ayala R, Chau K, Liang M, Madrid AM, Donahue TR, Glaspy JA, Presta L, Slamon DJ. PMID: 37788341.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    5. Association of Inpatient Palliative Care Consultation with Clinical and Financial Outcomes for Pancreatic Cancer. Ann Surg Oncol. 2024 Feb; 31(2):1328-1335. Kim S, Chervu N, Premji A, Mallick S, Verma A, Ali K, Benharash P, Donahue T. PMID: 37957512.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Machine Learning Based Prediction of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy. Ann Surg. 2023 Nov 10. Verma A, Balian J, Hadaya J, Premji A, Shimizu T, Donahue T, Benharash P. PMID: 37947154.
      View in: PubMed   Mentions:    Fields:    
    7. Establishing a mouse model of lung metastases using ultrasound-guided right heart ventricle injection. STAR Protoc. 2023 Dec 15; 4(4):102698. Labora A, Creech A, Lee H, Tabornal E, Radu C, Donahue T. PMID: 37925631; PMCID: PMC10652205.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. MEK Inhibition Sensitizes Pancreatic Cancer to STING Agonism by Tumor Cell-intrinsic Amplification of Type I IFN Signaling. Clin Cancer Res. 2023 08 15; 29(16):3130-3141. Ghukasyan R, Liang K, Chau K, Li L, Chan C, Abt ER, Le T, Park JY, Wu N, Premji A, Damoiseaux R, Luu T, Labora A, Rashid K, Link JM, Radu CG, Donahue TR. PMID: 37195712; PMCID: PMC10865884.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Ampullary Adenocarcinoma, Version 1.2023, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023 07; 21(7):753-782. Chiorean EG, Chiaro MD, Tempero MA, Malafa MP, Benson AB, Cardin DB, Christensen JA, Chung V, Czito B, Dillhoff M, Donahue TR, Dotan E, Fountzilas C, Glazer ES, Hardacre J, Hawkins WG, Klute K, Ko AH, Kunstman JW, LoConte N, Lowy AM, Masood A, Moravek C, Nakakura EK, Narang AK, Nardo L, Obando J, Polanco PM, Reddy S, Reyngold M, Scaife C, Shen J, Truty MJ, Vollmer C, Wolff RA, Wolpin BM, Rn BM, Lubin S, Darlow SD. PMID: 37433437.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    10. Learning Curves in Establishing a New Minimally Invasive Pancreas Program. Am Surg. 2023 Oct; 89(10):4166-4170. Park JY, Mirzaie S, Premji A, Seo Y, Mederos M, Hines J, Donahue T, Tomlinson J, King J, Girgis M. PMID: 37279455.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Invited Commentary: Adjuvant Chemotherapy Is Beneficial in Stage III Ampullary Adenocarcinoma. J Am Coll Surg. 2023 09 01; 237(3):512-514. Premji AM, Donahue TR. PMID: 37260119.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Generation of liver metastases in a mouse model using ultrasound-guided intravenous injection. STAR Protoc. 2023 Mar 15; 4(2):102163. Labora A, Lee H, Chan C, Tabornal E, Le T, Rashid K, Abt E, Yamao T, Mandl H, Creech A, Premji A, Li L, Link J, Wu N, Radu C, Donahue T. PMID: 36930646; PMCID: PMC10036864.
      View in: PubMed   Mentions:    Fields:    
    13. Higher Numbers of Examined Lymph Nodes Are Associated with Increased Survival in Resected, Treatment-Naïve, Node-Positive Esophageal, Gastric, Pancreatic, and Colon Cancers. J Gastrointest Surg. 2023 06; 27(6):1197-1207. Ghukasyan R, Banerjee S, Childers C, Labora A, McClintick D, Girgis M, Varley P, Dann A, Donahue T. PMID: 36854990.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Construction of a radiogenomic association map of pancreatic ductal adenocarcinoma. BMC Cancer. 2023 Feb 27; 23(1):189. Jamshidi N, Senthilvelan J, Dawson DW, Donahue TR, Kuo MD. PMID: 36843111; PMCID: PMC9969670.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer. Cancer Discov. 2023 02 06; 13(2):298-311. Kemp SB, Cheng N, Markosyan N, Sor R, Kim IK, Hallin J, Shoush J, Quinones L, Brown NV, Bassett JB, Joshi N, Yuan S, Smith M, Vostrejs WP, Perez-Vale KZ, Kahn B, Mo F, Donahue TR, Radu CG, Clendenin C, Christensen JG, Vonderheide RH, Stanger BZ. PMID: 36472553; PMCID: PMC9900321.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    16. Race, Insurance, and Sex-Based Disparities in Access to High-Volume Centers for Pancreatectomy. Ann Surg Oncol. 2023 May; 30(5):3002-3010. Williamson CG, Ebrahimian S, Sakowitz S, Aguayo E, Kronen E, Donahue TR, Benharash P. PMID: 36592257; PMCID: PMC10085903.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Robotic versus open pancreaticoduodenectomy in elderly patients: a propensity score-matched analysis. HPB (Oxford). 2023 03; 25(3):301-310. Mederos MA, Starr S, Park JY, King JC, Tomlinson JS, Hines OJ, Donahue TR, Girgis MD. PMID: 36529625.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Compliance of National Cancer Institute-Designated Cancer Centers With January 2021 Price Transparency Requirements. JAMA Surg. 2022 10 01; 157(10):959-960. Childers CP, Guorgui J, Siddiqui S, Donahue T. PMID: 35947377; PMCID: PMC9366656.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Purine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity. J Clin Invest. 2022 08 15; 132(16). Abt ER, Rashid K, Le TM, Li S, Lee HR, Lok V, Li L, Creech AL, Labora AN, Mandl HK, Lam AK, Cho A, Rezek V, Wu N, Abril-Rodriguez G, Rosser EW, Mittelman SD, Hugo W, Mehrling T, Bantia S, Ribas A, Donahue TR, Crooks GM, Wu TT, Radu CG. PMID: 35653193; PMCID: PMC9374381.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    20. A Novel Expert Coaching Model in Urology, Aimed at Accelerating the Learning Curve in Robotic Prostatectomy. J Surg Educ. 2022 Nov-Dec; 79(6):1480-1488. Fainberg J, Vanden Berg RNW, Chesnut G, Coleman JA, Donahue T, Ehdaie B, Goh AC, Laudone VP, Lee T, Pyon J, Scardino PT, Smith RC. PMID: 35872029; PMCID: PMC10353766.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. 18F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models. J Nucl Med. 2023 01; 64(1):117-123. Le TM, Lee HR, Abt ER, Rashid K, Creech AL, Liang K, Cui J, Cho A, Wei L, Labora A, Chan C, Sanchez E, Kriti K, Karin D, Li L, Wu N, Mona C, Carlucci G, Hugo W, Wu TT, Donahue TR, Czernin J, Radu CG. PMID: 35738905; PMCID: PMC9841248.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    22. Porcupine Inhibition Disrupts Mitochondrial Function and Homeostasis in WNT Ligand-Addicted Pancreatic Cancer. Mol Cancer Ther. 2022 06 01; 21(6):936-947. Aguilera KY, Le T, Riahi R, Lay AR, Hinz S, Saadat EA, Vashisht AA, Wohlschlegel J, Donahue TR, Radu CG, Dawson DW. PMID: 35313331; PMCID: PMC9167706.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Long-term Outcomes of Local and Metastatic Small Cell Carcinoma of the Urinary Bladder and Genomic Analysis of Patients Treated With Neoadjuvant Chemotherapy. Clin Genitourin Cancer. 2022 10; 20(5):431-441. Teo MY, Guercio BJ, Arora A, Hao X, Regazzi AM, Donahue T, Herr HW, Goh AC, Cha EK, Pietzak E, Donat SM, Dalbagni G, Bochner BH, Olgac S, Sarungbam J, Sirintrapun SJ, Chen YB, Gopalan A, Fine SW, Tickoo SK, Reuter VE, Weigelt B, Schultheis AM, Funt SA, Bajorin DF, Solit DB, Iyer G, Ostrovnaya I, Rosenberg JE, Al-Ahmadie H. PMID: 35676169.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Emotional Regulation in Surgery: Fostering Well-Being, Performance, and Leadership. J Surg Res. 2022 09; 277:A25-A35. Greenberg AL, Sullins VF, Donahue TR, Sundaram VM, Saldinger PF, Divino CM, Anton NE, Stefanidis D, Reilly LM, Egan RJ, Beals CKJ, Riall TS, Duh QY, Mukhtar RA, Hirose K, Lebares CC. PMID: 35307162.
      View in: PubMed   Mentions:    Fields:    
    25. Feasibility of a geriatric comanagement (GERICO) pilot program for patients 75 and older undergoing radical cystectomy. Eur J Surg Oncol. 2022 06; 48(6):1427-1432. Letica-Kriegel AS, Tin AL, Nash GM, Benfante NE, McNeil N, Vickers AJ, Bochner B, Donat SM, Goh A, Dalbagni G, Donahue T, Cha EK, Pietzak E, Herr H, Korc-Grodzicki B, Shahrokni A. PMID: 35304038; PMCID: PMC9232991.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    26. Association of research timing with surgery resident perceptions of operative autonomy and satisfaction: A multi-institutional study. Surgery. 2022 07; 172(1):102-109. Schumm MA, Huang IA, Blair KJ, Nameth C, Tseng CH, Quach C, Wagner JP, Lewis CE, Donahue TR, Tillou A. PMID: 35256194.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells. Cell Rep. 2022 01 11; 38(2):110236. Abt ER, Le TM, Dann AM, Capri JR, Poddar S, Lok V, Li L, Liang K, Creech AL, Rashid K, Kim W, Wu N, Cui J, Cho A, Lee HR, Rosser EW, Link JM, Czernin J, Wu TT, Damoiseaux R, Dawson DW, Donahue TR, Radu CG. PMID: 35021095; PMCID: PMC8893345.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    28. Discovery and characterization of circulating tumor cell clusters in neuroendocrine tumor patients using nanosubstrate-embedded microchips. Biosens Bioelectron. 2022 Mar 01; 199:113854. Sun N, Yang Y, Miao H, Redublo P, Liu H, Liu W, Huang YW, Teng PC, Zhang C, Zhang RY, Smalley M, Yang P, Chou SJ, Huai K, Zhang Z, Lee YT, Wang JJ, Wang J, Liang IY, Zhang TX, Zhang D, Liang L, Weiss PS, Posadas EM, Donahue T, Hecht JR, Allen-Auerbach MS, Bergsland EK, Hope TA, Pei R, Zhu Y, Tseng HR, Heaney AP. PMID: 34896918; PMCID: PMC8900541.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    29. Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. 2021 Dec; 600(7889):E18. Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T. PMID: 34848876.
      View in: PubMed   Mentions: 1     Fields:    
    30. Pathological treatment response has different prognostic implications for pancreatic cancer patients treated with neoadjuvant chemotherapy or chemoradiotherapy. Surgery. 2022 05; 171(5):1379-1387. Maeda S, Mederos MA, Chawla A, Moore AM, Shoucair S, Yin L, Burkhart RA, Cameron JL, Park JY, Girgis MD, Wainberg ZA, Hines OJ, Fernandez-Del Castillo C, Qadan M, Lillemoe KD, Ferrone CR, He J, Wolfgang CL, Burns WR, Yu J, Donahue TR. PMID: 34774289.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    31. STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [18F]FLT PET imaging. Proc Natl Acad Sci U S A. 2021 09 07; 118(36). Liang K, Abt ER, Le TM, Cho A, Dann AM, Cui J, Li L, Rashid K, Creech AL, Wei L, Ghukasyan R, Rosser EW, Wu N, Carlucci G, Czernin J, Donahue TR, Radu CG. PMID: 34480004; PMCID: PMC8433573.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    32. Surgical resection of high-grade nonfunctional pancreatic neuroendocrine carcinoma is associated with improved survival. J Surg Oncol. 2021 Dec; 124(8):1373-1380. Jiang J, Park J, Kim S, Daan A, Donahue T, Girgis MD. PMID: 34406651.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Proteome heterogeneity and malignancy detection in pancreatic cyst fluids. Clin Transl Med. 2021 08; 11(8):e506. Pan S, Brand RE, Lai LA, Dawson DW, Donahue TR, Kim S, Khalaf NI, Othman MO, Fisher WE, Bronner MP, Simeone DM, Brentnall TA, Chen R. PMID: 34459141; PMCID: PMC8382978.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. Factors Associated With General Surgery Residents' Operative Experience During the COVID-19 Pandemic. JAMA Surg. 2021 08 01; 156(8):767-774. Purdy AC, de Virgilio C, Kaji AH, Shields Frey E, Lee-Kong S, Inaba K, Gauvin JM, Neville AL, Donahue TR, Smith BR, Salcedo ES, Calhoun KE, Poola VP, Namm JP, Spain DA, Dickinson KJ, Tanner T, Wolfe M, Amersi F. PMID: 33929493; PMCID: PMC8087976.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsPHPublic Health
    35. Persistence of Gender Bias Over Four Decades of Surgical Training. J Surg Educ. 2021 Nov-Dec; 78(6):1868-1877. Ouyang K, Huang IA, Wagner JP, Wu J, Chen F, Quach C, Donahue TR, Hines OJ, Hiatt JR, Tillou A. PMID: 34294569.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. 18F-FDG PET/CT Imaging Biomarkers for Early and Late Evaluation of Response to First-Line Chemotherapy in Patients with Pancreatic Ductal Adenocarcinoma. J Nucl Med. 2022 Feb; 63(2):199-204. Benz MR, Armstrong WR, Ceci F, Polverari G, Donahue TR, Wainberg ZA, Quon A, Auerbach M, Girgis MD, Herrmann K, Czernin J, Calais J. PMID: 34272317.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    37. The Duration of Antibiotics Prophylaxis at the Time of Catheter Removal after Radical Prostatectomy: Clinically Integrated, Cluster, Randomized Trial. J Urol. 2021 09; 206(3):662-668. Ehdaie B, Jibara G, Sjoberg DD, Laudone V, Eastham J, Touijer K, Scardino P, Donahue T, Goh A, Vickers A. PMID: 33904798; PMCID: PMC8441991.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    38. Pancreatic Adenocarcinoma, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2021 04 01; 19(4):439-457. Tempero MA, Malafa MP, Al-Hawary M, Behrman SW, Benson AB, Cardin DB, Chiorean EG, Chung V, Czito B, Del Chiaro M, Dillhoff M, Donahue TR, Dotan E, Ferrone CR, Fountzilas C, Hardacre J, Hawkins WG, Klute K, Ko AH, Kunstman JW, LoConte N, Lowy AM, Moravek C, Nakakura EK, Narang AK, Obando J, Polanco PM, Reddy S, Reyngold M, Scaife C, Shen J, Vollmer C, Wolff RA, Wolpin BM, Lynn B, George GV. PMID: 33845462.
      View in: PubMed   Mentions: 254     Fields:    Translation:Humans
    39. NAD+ depletion by type I interferon signaling sensitizes pancreatic cancer cells to NAMPT inhibition. Proc Natl Acad Sci U S A. 2021 02 23; 118(8). Moore AM, Zhou L, Cui J, Li L, Wu N, Yu A, Poddar S, Liang K, Abt ER, Kim S, Ghukasyan R, Khachatourian N, Pagano K, Elliott I, Dann AM, Riahi R, Le T, Dawson DW, Radu CG, Donahue TR. PMID: 33597293; PMCID: PMC7923374.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    40. Natural history, response to systemic therapy, and genomic landscape of plasmacytoid urothelial carcinoma. Br J Cancer. 2021 03; 124(7):1214-1221. Teo MY, Al-Ahmadie H, Seier K, Tully C, Regazzi AM, Pietzak E, Solit DB, Tickoo S, Reuter V, Cha EK, Herr H, Donahue T, Donat SM, Dalbagni G, Bochner BH, Funt S, Iyer GV, Bajorin DF, Ostrovnaya I, Rosenberg JE. PMID: 33473164; PMCID: PMC8007750.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    41. A multi-institutional study assessing general surgery faculty teaching evaluations. Am J Surg. 2021 08; 222(2):334-340. Shellito AD, de Virgilio C, Kaji AH, Harrington DW, Robertson JM, Zern NK, Spain DA, Dickinson KJ, Smink DS, Cho NL, Donahue T, Aarons CB, Namm JP, Amersi F, Tanner TN, Frey ES, Jarman BT, Smith BR, Gauvin JM, Brasel KJ, Salcedo ES, Murayama K, Poola VP, Mpinga E, Inaba K, Calhoun KE. PMID: 33388134.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Examining the Accuracy of Self-Reported Smoking-Related Exposure among Recently Diagnosed Nonmuscle Invasive Bladder Cancer Patients. J Urol. 2021 May; 205(5):1321-1325. Petruzella S, Bochner BH, Kenney J, Whiting K, Sadeghi K, Benfante N, Cha EK, Dalbagni G, Donahue T, Donat SM, Herr HW, Pietzak E, Orlow I, Ostroff JS, Furberg H. PMID: 33356484; PMCID: PMC9262154.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity. Cancer Discov. 2021 03; 11(3):714-735. Hong A, Piva M, Liu S, Hugo W, Lomeli SH, Zoete V, Randolph CE, Yang Z, Wang Y, Lee JJ, Lo SJ, Sun L, Vega-Crespo A, Garcia AJ, Shackelford DB, Dubinett SM, Scumpia PO, Byrum SD, Tackett AJ, Donahue TR, Michielin O, Holmen SL, Ribas A, Moriceau G, Lo RS. PMID: 33318037; PMCID: PMC7933113.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    44. Multi-institutional virtual mock oral examinations for general surgery residents in the era of COVID-19. Am J Surg. 2021 02; 221(2):429-430. Huang IA, Lu Y, Wagner JP, Quach C, Donahue TR, Tillou A, Chen F, Wu J. PMID: 33218677; PMCID: PMC7664339.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    45. Poorly differentiated histologic grade correlates with worse survival in SMAD4 negative pancreatic adenocarcinoma patients. J Surg Oncol. 2021 Feb; 123(2):389-398. Park JY, King J, Reber H, Joe Hines O, Mederos MA, Wang HL, Dawson D, Wainberg Z, Donahue T, Girgis M. PMID: 33146409.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. Risk Factors for Failure of Splenic Angioembolization: A Multicenter Study of Level I Trauma Centers. J Surg Res. 2021 01; 257:227-231. Bankhead-Kendall B, Teixeira P, Musonza T, Donahue T, Regner J, Harrell K, Brown CVR, Texas Trauma Study Group. PMID: 32861100.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    47. Use of ratiometrically designed nanocarrier targeting CDK4/6 and autophagy pathways for effective pancreatic cancer treatment. Nat Commun. 2020 08 25; 11(1):4249. Ji Y, Liu X, Li J, Xie X, Huang M, Jiang J, Liao YP, Donahue T, Meng H. PMID: 32843618; PMCID: PMC7447818.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    48. Endoscopic placement of pancreatic stent for "Deep" pancreatic enucleations operative technique and preliminary experience at two high-volume centers. Surg Endosc. 2020 06; 34(6):2796-2802. Giuliani T, Marchegiani G, Girgis MD, Crinò SF, Muthusamy VR, Bernardoni L, Pea A, Ramera M, Paiella S, Landoni L, Gabbrielli A, Salvia R, Donahue TR, Bassi C. PMID: 32180000.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    49. Isoquinoline thiosemicarbazone displays potent anticancer activity with in vivo efficacy against aggressive leukemias. RSC Med Chem. 2020 Mar 01; 11(3):392-410. Sun DL, Poddar S, Pan RD, Rosser EW, Abt ER, Van Valkenburgh J, Le TM, Lok V, Hernandez SP, Song J, Li J, Turlik A, Chen X, Cheng CA, Chen W, Mona CE, Stuparu AD, Vergnes L, Reue K, Damoiseaux R, Zink JI, Czernin J, Donahue TR, Houk KN, Jung ME, Radu CG. PMID: 33479645; PMCID: PMC7593890.
      View in: PubMed   Mentions: 3  
    50. Cancer-Related Venous Thromboembolism as a Complication and Negative Prognostic Factor. Gastroenterology. 2020 04; 158(5):1214-1215. Ghukasyan R, Donahue TR. PMID: 32061863.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Impact of resection margin status on survival in pancreatic cancer patients after neoadjuvant treatment and pancreatoduodenectomy. Surgery. 2020 05; 167(5):803-811. Maeda S, Moore AM, Yohanathan L, Hata T, Truty MJ, Smoot RL, Cleary SP, Nagorney DM, Grotz TE, Park EJ, Girgis MD, Reber HA, Motoi F, Masuda T, Unno M, Kendrick ML, Donahue TR. PMID: 31992444.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    52. Histone deacetylase inhibition is synthetically lethal with arginine deprivation in pancreatic cancers with low argininosuccinate synthetase 1 expression. Theranostics. 2020; 10(2):829-840. Kim SS, Xu S, Cui J, Poddar S, Le TM, Hayrapetyan H, Li L, Wu N, Moore AM, Zhou L, Yu AC, Dann AM, Elliott IA, Abt ER, Kim W, Dawson DW, Radu CG, Donahue TR. PMID: 31903153; PMCID: PMC6929997.
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    53. The Utility of EUS-FNA to Determine Surgical Candidacy in Patients with Pancreatic Cancer after Neoadjuvant Therapy. J Gastrointest Surg. 2020 12; 24(12):2807-2813. Ehrlich D, Ather N, Rahal H, Donahue TR, Hines OJ, Kim S, Sedarat A, Muthusamy VR, Watson R. PMID: 31823316.
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    54. Influence of Student Loan Debt on General Surgery Resident Career and Lifestyle Decision-Making. J Am Coll Surg. 2020 02; 230(2):173-181. Gray K, Kaji AH, Wolfe M, Calhoun K, Amersi F, Donahue T, Smith BR, Salcedo ES, Murayama K, de Virgilio C, Surgery Educators Workgroup. PMID: 31783093.
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    55. Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism. Cell Chem Biol. 2020 02 20; 27(2):197-205.e6. Abt ER, Rosser EW, Durst MA, Lok V, Poddar S, Le TM, Cho A, Kim W, Wei L, Song J, Capri JR, Xu S, Wu N, Slavik R, Jung ME, Damoiseaux R, Czernin J, Donahue TR, Lavie A, Radu CG. PMID: 31734178; PMCID: PMC7035983.
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    56. Career Goals, Salary Expectations, and Salary Negotiation Among Male and Female General Surgery Residents. JAMA Surg. 2019 11 01; 154(11):1023-1029. Gray K, Neville A, Kaji AH, Wolfe M, Calhoun K, Amersi F, Donahue T, Arnell T, Jarman B, Inaba K, Melcher M, Morris JB, Smith B, Reeves M, Gauvin J, Salcedo ES, Sidwell R, Murayama K, Damewood R, Poola VP, Dent D, de Virgilio C. PMID: 31461140; PMCID: PMC6714007.
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    57. Pancreatic Cancer. JAMA. 2019 10 08; 322(14):1426. Moore A, Donahue T. PMID: 31593274; PMCID: PMC7021307.
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    58. Factors associated with general surgery residents' decisions regarding fellowship and subspecialty stratified by burnout and quality of life. Am J Surg. 2019 12; 218(6):1090-1095. McClintock NC, Gray KE, Neville AL, Kaji AH, Wolfe MM, Calhoun KE, Amersi FF, Donahue TR, Arnell TD, Jarman BT, Inaba K, Melcher ML, Morris JB, Smith BR, Reeves ME, Gauvin JM, Salcedo ES, Sidwell RA, Dent DL, Murayama KM, Damewood RB, Poola VP, de Virgilio CM. PMID: 31421896.
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    59. Impact of Changes in the American Joint Committee on Cancer Staging Manual, Eighth Edition, for Pancreatic Ductal Adenocarcinoma. Pancreas. 2019 08; 48(7):876-882. Kassardjian A, Stanzione N, Donahue TR, Wainberg ZA, Damato L, Wang HL. PMID: 31268985.
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    60. Epidural Analgesia Improves Postoperative Pain Control but Impedes Early Discharge in Patients Undergoing Pancreatic Surgery. Pancreas. 2019 May/Jun; 48(5):719-725. Kim SS, Niu X, Elliott IA, Jiang JP, Dann AM, Damato LM, Chung H, Girgis MD, King JC, Hines OJ, Rahman S, Donahue TR. PMID: 31091221; PMCID: PMC6521855.
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    61. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. 2019 05; 569(7754):131-135. Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, Woo G, Fang L, Santisakultarm TP, Manor U, Xu R, Becerra CR, Borazanci E, Von Hoff DD, Grandgenett PM, Hollingsworth MA, Leblanc M, Umetsu SE, Collisson EA, Scadeng M, Lowy AM, Donahue TR, Reya T, Downes M, Evans RM, Wahl GM, Pawson T, Tian R, Hunter T. PMID: 30996350; PMCID: PMC6565370.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansAnimalsCells
    62. Lysosome inhibition sensitizes pancreatic cancer to replication stress by aspartate depletion. Proc Natl Acad Sci U S A. 2019 04 02; 116(14):6842-6847. Elliott IA, Dann AM, Xu S, Kim SS, Abt ER, Kim W, Poddar S, Moore A, Zhou L, Williams JL, Capri JR, Ghukasyan R, Matsumura C, Tucker DA, Armstrong WR, Cabebe AE, Wu N, Li L, Le TM, Radu CG, Donahue TR. PMID: 30894490; PMCID: PMC6452719.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    63. Association of Hospital Length of Stay and Complications With Readmission After Open Pancreaticoduodenectomy. JAMA Surg. 2019 Jan 01; 154(1):88-90. Jiang J, Upfill-Brown A, Dann AM, Kim SS, Girgis MD, King JC, Donahue TR. PMID: 30325979; PMCID: PMC6439846.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    64. A Prognostic Scoring System for the Prediction of Metastatic Recurrence Following Curative Resection of Pancreatic Neuroendocrine Tumors. J Gastrointest Surg. 2019 07; 23(7):1392-1400. Sho S, Court CM, Winograd P, Toste PA, Pisegna JR, Lewis M, Donahue TR, Hines OJ, Reber HA, Dawson DW, Tomlinson JS. PMID: 30353489; PMCID: PMC6736531.
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    65. Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming. Gut. 2019 07; 68(7):1271-1286. Koutsioumpa M, Hatziapostolou M, Polytarchou C, Tolosa EJ, Almada LL, Mahurkar-Joshi S, Williams J, Tirado-Rodriguez AB, Huerta-Yepez S, Karavias D, Kourea H, Poultsides GA, Struhl K, Dawson DW, Donahue TR, Fernández-Zapico ME, Iliopoulos D. PMID: 30337373; PMCID: PMC6697184.
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    66. Low-Dose Continuous 5-Fluorouracil Combined with Leucovorin, nab-Paclitaxel, Oxaliplatin, and Bevacizumab for Patients with Advanced Pancreatic Cancer: A Retrospective Analysis. Target Oncol. 2018 08; 13(4):461-468. Isacoff WH, Reber HA, Bedford R, Hoos W, Rahib L, Upfill-Brown A, Donahue T, Hines OJ. PMID: 29882102; PMCID: PMC6096752.
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    67. Carcinoembryonic Antigen for Diagnosis of Colorectal Cancer Recurrence. JAMA. 2018 Jul 17; 320(3):298-299. Kim SS, Donahue TR, Girgis MD. PMID: 30027230.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    68. Laparoscopic Cholecystectomy. JAMA. 2018 05 01; 319(17):1834. Kim SS, Donahue TR. PMID: 29715356.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    69. Formal sacrocolpopexy reduces hypercontinence rates in female neobladder formation. Neurourol Urodyn. 2018 09; 37(7):2281-2285. Stearns G, Donahue T, Fathollahi A, Dalbagni G, Sandhu J. PMID: 29664125.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    70. Use of Entrustable Professional Activities in the Assessment of Surgical Resident Competency. JAMA Surg. 2018 04 01; 153(4):335-343. Wagner JP, Lewis CE, Tillou A, Agopian VG, Quach C, Donahue TR, Hines OJ. PMID: 29141086; PMCID: PMC5933400.
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    71. Dual-Modality Immuno-PET and Near-Infrared Fluorescence Imaging of Pancreatic Cancer Using an Anti-Prostate Stem Cell Antigen Cys-Diabody. J Nucl Med. 2018 09; 59(9):1398-1405. Zettlitz KA, Tsai WK, Knowles SM, Kobayashi N, Donahue TR, Reiter RE, Wu AM. PMID: 29602820; PMCID: PMC6126441.
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    72. Pasireotide does not prevent postoperative pancreatic fistula: a prospective study. HPB (Oxford). 2018 05; 20(5):418-422. Elliott IA, Dann AM, Ghukasyan R, Damato L, Girgis MD, King JC, Hines OJ, Reber HA, Donahue TR. PMID: 29398424.
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    73. Association of General Surgery Resident Remediation and Program Director Attitudes With Resident Attrition. JAMA Surg. 2017 Dec 01; 152(12):1134-1140. Schwed AC, Lee SL, Salcedo ES, Reeves ME, Inaba K, Sidwell RA, Amersi F, Are C, Arnell TD, Damewood RB, Dent DL, Donahue T, Gauvin J, Hartranft T, Jacobsen GR, Jarman BT, Melcher ML, Mellinger JD, Morris JB, Nehler M, Smith BR, Wolfe M, Kaji AH, de Virgilio C. PMID: 28813585; PMCID: PMC5831434.
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    74. Distinction of Risk Factors for Superficial vs Organ-Space Surgical Site Infections After Pancreatic Surgery. JAMA Surg. 2017 Nov 01; 152(11):1023-1029. Elliott IA, Chan C, Russell TA, Dann AM, Williams JL, Damato L, Chung H, Girgis MD, Hines OJ, Reber HA, Donahue TR. PMID: 28700780; PMCID: PMC5710411.
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    75. A Comprehensive Assessment of Accurate Lymph Node Staging and Preoperative Detection in Resected Pancreatic Cancer. J Gastrointest Surg. 2018 02; 22(2):295-302. Masuda T, Dann AM, Elliott IA, Baba H, Kim S, Sedarat A, Muthusamy VR, Girgis MD, Joe Hines O, Reber HA, Donahue TR. PMID: 29043580.
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    76. ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. Nat Commun. 2017 08 14; 8(1):241. Le TM, Poddar S, Capri JR, Abt ER, Kim W, Wei L, Uong NT, Cheng CM, Braas D, Nikanjam M, Rix P, Merkurjev D, Zaretsky J, Kornblum HI, Ribas A, Herschman HR, Whitelegge J, Faull KF, Donahue TR, Czernin J, Radu CG. PMID: 28808226; PMCID: PMC5556071.
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    77. Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer. J Clin Invest. 2017 May 01; 127(5):2007-2018. Liu X, Lin P, Perrett I, Lin J, Liao YP, Chang CH, Jiang J, Wu N, Donahue T, Wainberg Z, Nel AE, Meng H. PMID: 28414297; PMCID: PMC5409788.
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    78. Preoperative Treatment With FOLFIRINOX and Successful Resection for a Patient With Mixed Acinar-Endocrine Carcinoma of the Pancreas. Pancreas. 2017 Apr; 46(4):e32-e34. Sugimoto M, Hines OJ, Dawson DW, Muthusamy VR, Reber HA, Donahue TR. PMID: 28291165; PMCID: PMC5354082.
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    79. Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts. Oncotarget. 2017 Mar 21; 8(12):19074-19088. Nguyen AH, Elliott IA, Wu N, Matsumura C, Vogelauer M, Attar N, Dann A, Ghukasyan R, Toste PA, Patel SG, Williams JL, Li L, Dawson DW, Radu C, Kurdistani SK, Donahue TR. PMID: 27894105; PMCID: PMC5386671.
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    80. Evaluation of the 2015 AGA guidelines on pancreatic cystic neoplasms in a large surgically confirmed multicenter cohort. Endosc Int Open. 2017 Mar; 5(3):E201-E208. Ge PS, Muthusamy VR, Gaddam S, Jaiyeola DM, Kim S, Sedarat A, Donahue TR, Hosford L, Wilson RH, Grande DP, Keswani RN, Kushnir VM, Mullady D, Edmundowicz SA, Early DS, Komanduri S, Wani S, Watson RR. PMID: 28317015; PMCID: PMC5352566.
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    81. Assessment of a Revised Management Strategy for Patients With Intraductal Papillary Mucinous Neoplasms Involving the Main Pancreatic Duct. JAMA Surg. 2017 01 18; 152(1):e163349. Sugimoto M, Elliott IA, Nguyen AH, Kim S, Muthusamy VR, Watson R, Hines OJ, Dawson DW, Reber HA, Donahue TR. PMID: 27829085.
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    82. Association of Histopathologic Phenotype of Periampullary Adenocarcinomas With Survival. JAMA Surg. 2017 01 01; 152(1):82-88. Williams JL, Chan CK, Toste PA, Elliott IA, Vasquez CR, Sunjaya DB, Swanson EA, Koo J, Hines OJ, Reber HA, Dawson DW, Donahue TR. PMID: 27732711.
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    83. Stiffness of pancreatic cancer cells is associated with increased invasive potential. Integr Biol (Camb). 2016 12 05; 8(12):1232-1245. Nguyen AV, Nyberg KD, Scott MB, Welsh AM, Nguyen AH, Wu N, Hohlbauch SV, Geisse NA, Gibb EA, Robertson AG, Donahue TR, Rowat AC. PMID: 27761545; PMCID: PMC5866717.
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    84. Plectin-1 as a Biomarker of Malignant Progression in Intraductal Papillary Mucinous Neoplasms: A Multicenter Study. Pancreas. 2016 10; 45(9):1353-8. Moris M, Dawson DW, Jiang J, Lewis J, Nassar A, Takeuchi KK, Lay AR, Zhai Q, Donahue TR, Kelly KA, Crawford HC, Wallace M. PMID: 27101571; PMCID: PMC5021548.
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    85. Polymicrobial Transjugular Intrahepatic Portosystemic Shunt Infection in the Setting of a Prior Hepaticojejunostomy Anastomosis: A Case Report. Case Rep Pancreat Cancer. 2016; 2(1):62-64. Gupta P, Donahue TR. PMID: 30631819; PMCID: PMC6319683.
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    86. Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality. Trends Endocrinol Metab. 2016 11; 27(11):770-781. Donahue TR, Dawson DW. PMID: 27461042; PMCID: PMC5075262.
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    87. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G1124-37. Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. PMID: 27151939; PMCID: PMC5005285.
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    88. Pancreatic Cyst Disease: A Review. JAMA. 2016 05 03; 315(17):1882-93. Stark A, Donahue TR, Reber HA, Hines OJ. PMID: 27139061.
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    89. CA19-9 Normalization During Pre-operative Treatment Predicts Longer Survival for Patients with Locally Progressed Pancreatic Cancer. J Gastrointest Surg. 2016 07; 20(7):1331-42. Williams JL, Kadera BE, Nguyen AH, Muthusamy VR, Wainberg ZA, Hines OJ, Reber HA, Donahue TR. PMID: 27114246; PMCID: PMC4919020.
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    90. [18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity. Proc Natl Acad Sci U S A. 2016 Apr 12; 113(15):4027-32. Kim W, Le TM, Wei L, Poddar S, Bazzy J, Wang X, Uong NT, Abt ER, Capri JR, Austin WR, Van Valkenburgh JS, Steele D, Gipson RM, Slavik R, Cabebe AE, Taechariyakul T, Yaghoubi SS, Lee JT, Sadeghi S, Lavie A, Faull KF, Witte ON, Donahue TR, Phelps ME, Herschman HR, Herrmann K, Czernin J, Radu CG. PMID: 27035974; PMCID: PMC4839461.
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    91. Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK. Mol Cancer Res. 2016 05; 14(5):437-47. Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. PMID: 26979711; PMCID: PMC4867256.
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    92. Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma. Mol Cancer Ther. 2016 05; 15(5):1043-52. Gifford JB, Huang W, Zeleniak AE, Hindoyan A, Wu H, Donahue TR, Hill R. PMID: 26939701.
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    93. Irinotecan Delivery by Lipid-Coated Mesoporous Silica Nanoparticles Shows Improved Efficacy and Safety over Liposomes for Pancreatic Cancer. ACS Nano. 2016 Feb 23; 10(2):2702-15. Liu X, Situ A, Kang Y, Villabroza KR, Liao Y, Chang CH, Donahue T, Nel AE, Meng H. PMID: 26835979; PMCID: PMC4851343.
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    94. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. 2016 06; 159(6):1520-1527. Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. PMID: 26847803; PMCID: PMC4856542.
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    95. Predictors for Surgical Referral in Patients With Pancreatic Cystic Lesions Undergoing Endoscopic Ultrasound: Results From a Large Multicenter Cohort Study. Pancreas. 2016 Jan; 45(1):51-7. Ge PS, Gaddam S, Keach JW, Mullady D, Fukami N, Edmundowicz SA, Azar RR, Shah RJ, Murad FM, Kushnir VM, Ghassemi KF, Sedarat A, Watson RR, Amateau SK, Brauer BC, Yen RD, Hosford L, Hollander T, Donahue TR, Schulick RD, Edil BH, McCarter MD, Gajdos C, Attwell AR, Muthusamy VR, Early DS, Wani S. PMID: 26262589.
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    96. Reading Habits of General Surgery Residents and Association With American Board of Surgery In-Training Examination Performance. JAMA Surg. 2015 Sep; 150(9):882-9. Kim JJ, Kim DY, Kaji AH, Gifford ED, Reid C, Sidwell RA, Reeves ME, Hartranft TH, Inaba K, Jarman BT, Are C, Galante JM, Amersi F, Smith BR, Melcher ML, Nelson MT, Donahue T, Jacobsen G, Arnell TD, de Virgilio C. PMID: 26176352.
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    97. Program Factors That Influence American Board of Surgery In-Training Examination Performance: A Multi-Institutional Study. J Surg Educ. 2015 Nov-Dec; 72(6):e236-42. Kim JJ, Gifford ED, Moazzez A, Sidwell RA, Reeves ME, Hartranft TH, Inaba K, Jarman BT, Are C, Galante JM, Amersi F, Smith BR, Melcher ML, Nelson MT, Donahue T, Jacobsen G, Arnell TD, Lee S, Neville A, de Virgilio C. PMID: 26319103.
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    98. Pancreatic cancer patients with lymph node involvement by direct tumor extension have similar survival to those with node-negative disease. J Surg Oncol. 2015 Sep; 112(4):396-402. Williams JL, Nguyen AH, Rochefort M, Muthusamy VR, Wainberg ZA, Dawson DW, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. PMID: 26303811.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    99. Suboptimal accuracy of carcinoembryonic antigen in differentiation of mucinous and nonmucinous pancreatic cysts: results of a large multicenter study. Gastrointest Endosc. 2015 Dec; 82(6):1060-9. Gaddam S, Ge PS, Keach JW, Mullady D, Fukami N, Edmundowicz SA, Azar RR, Shah RJ, Murad FM, Kushnir VM, Watson RR, Ghassemi KF, Sedarat A, Komanduri S, Jaiyeola DM, Brauer BC, Yen RD, Amateau SK, Hosford L, Hollander T, Donahue TR, Schulick RD, Edil BH, McCarter M, Gajdos C, Attwell A, Muthusamy VR, Early DS, Wani S. PMID: 26077458.
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    100. Pancreatic cancer patient survival correlates with DNA methylation of pancreas development genes. PLoS One. 2015; 10(6):e0128814. Thompson MJ, Rubbi L, Dawson DW, Donahue TR, Pellegrini M. PMID: 26039411; PMCID: PMC4454596.
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    101. p85α is a microRNA target and affects chemosensitivity in pancreatic cancer. J Surg Res. 2015 Jun 15; 196(2):285-293. Toste PA, Li L, Kadera BE, Nguyen AH, Tran LM, Wu N, Madnick DL, Patel SG, Dawson DW, Donahue TR. PMID: 25846727; PMCID: PMC4442711.
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    102. Surgical management of pancreatic cancer--pancreaticoduodenectomy. Semin Oncol. 2015 Feb; 42(1):98-109. Donahue TR, Reber HA. PMID: 25726055.
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    103. Current recommendations for surveillance and surgery of intraductal papillary mucinous neoplasms may overlook some patients with cancer. J Gastrointest Surg. 2015 Feb; 19(2):258-65. Nguyen AH, Toste PA, Farrell JJ, Clerkin BM, Williams J, Muthusamy VR, Watson RR, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. PMID: 25373706; PMCID: PMC4305480.
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    104. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clin Cancer Res. 2015 Jan 01; 21(1):157-65. Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. PMID: 25348515; PMCID: PMC4286535.
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    105. Plastic biliary stent patency in patients with locally advanced pancreatic adenocarcinoma receiving downstaging chemotherapy. Gastrointest Endosc. 2015 Feb; 81(2):360-6. Ge PS, Hamerski CM, Watson RR, Komanduri S, Cinnor BB, Bidari K, Klapman JB, Lin CL, Shah JN, Wani S, Donahue TR, Muthusamy VR. PMID: 25442083.
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    106. Mucinous cystic neoplasms of the pancreas: are we overestimating malignant potential? Am Surg. 2014 Oct; 80(10):915-9. Nguyen D, Dawson DW, Hines OJ, Reber HA, Donahue TR. PMID: 25264629.
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    107. Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 2014 Sep 25; 159(1):80-93. Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, Shimosegawa T, Apte MV, Wilson JS, Ng B, Lau SL, Gunton JE, Wahl GM, Hunter T, Drebin JA, O'Dwyer PJ, Liddle C, Tuveson DA, Downes M, Evans RM. PMID: 25259922; PMCID: PMC4177038.
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    108. Stromal microRNA-21 levels predict response to 5-fluorouracil in patients with pancreatic cancer. J Surg Oncol. 2014 Dec; 110(8):952-9. Donahue TR, Nguyen AH, Moughan J, Li L, Tatishchev S, Toste P, Farrell JJ. PMID: 25132574; PMCID: PMC4232442.
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    109. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Mol Cancer Ther. 2014 Oct; 13(10):2303-14. Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. PMID: 25082960; PMCID: PMC4188417.
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    110. Assessment of resident operative performance using a real-time mobile Web system: preparing for the milestone age. J Surg Educ. 2014 Nov-Dec; 71(6):e41-6. Wagner JP, Chen DC, Donahue TR, Quach C, Hines OJ, Hiatt JR, Tillou A. PMID: 25037504.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    111. Locally advanced pancreatic cancer: association between prolonged preoperative treatment and lymph-node negativity and overall survival. JAMA Surg. 2014 Feb; 149(2):145-53. Kadera BE, Sunjaya DB, Isacoff WH, Li L, Hines OJ, Tomlinson JS, Dawson DW, Rochefort MM, Donald GW, Clerkin BM, Reber HA, Donahue TR. PMID: 24306217.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    112. Resolution of persistent pancreaticopleural fistula after an internal drainage procedure. Am Surg. 2014 Jan; 80(1):E19-21. Vasquez CR, Chestovich P, Muthusamy VR, Donahue TR. PMID: 24401504.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    113. A meta-analysis of gemcitabine biomarkers in patients with pancreaticobiliary cancers. Pancreas. 2013 Nov; 42(8):1303-10. Wei CH, Gorgan TR, Elashoff DA, Hines OJ, Farrell JJ, Donahue TR. PMID: 24152955; PMCID: PMC3813307.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    114. Nonfunctional pancreatic neuroendocrine tumors <2 cm on preoperative imaging are associated with a low incidence of nodal metastasis and an excellent overall survival. J Gastrointest Surg. 2013 Dec; 17(12):2105-13. Toste PA, Kadera BE, Tatishchev SF, Dawson DW, Clerkin BM, Muthusamy R, Watson R, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. PMID: 24101447.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    115. Polyp on ultrasound: now what? The association between gallbladder polyps and cancer. Am Surg. 2013 Oct; 79(10):1005-8. Donald G, Sunjaya D, Donahue T, Hines OJ. PMID: 24160788.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    116. Pancreatic surgery. Curr Opin Gastroenterol. 2013 Sep; 29(5):552-8. Donahue TR, Reber HA. PMID: 23892537.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    117. Should the duodenum be "the road less traveled" for biliary reconstruction? JAMA Surg. 2013 Sep; 148(9):865-6. Donahue TR. PMID: 23884302.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    118. MicroRNA-21 in pancreatic ductal adenocarcinoma tumor-associated fibroblasts promotes metastasis. PLoS One. 2013; 8(8):e71978. Kadera BE, Li L, Toste PA, Wu N, Adams C, Dawson DW, Donahue TR. PMID: 23991015; PMCID: PMC3750050.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    119. Impact of tumor grade on pancreatic cancer prognosis: validation of a novel TNMG staging system. Ann Surg Oncol. 2013 Dec; 20(13):4322-9. Rochefort MM, Ankeny JS, Kadera BE, Donald GW, Isacoff W, Wainberg ZA, Hines OJ, Donahue TR, Reber HA, Tomlinson JS. PMID: 23943022.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    120. Endoscopically acquired pancreatic cyst fluid microRNA 21 and 221 are associated with invasive cancer. Am J Gastroenterol. 2013 Aug; 108(8):1352-9. Farrell JJ, Toste P, Wu N, Li L, Wong J, Malkhassian D, Tran LM, Wu X, Li X, Dawson D, Wu H, Donahue TR. PMID: 23752880.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    121. Perioperative antibiotics for surgical site infection in pancreaticoduodenectomy: does the SCIP-approved regimen provide adequate coverage? Surgery. 2013 Aug; 154(2):190-6. Donald GW, Sunjaya D, Lu X, Chen F, Clerkin B, Eibl G, Li G, Tomlinson JS, Donahue TR, Reber HA, Hines OJ. PMID: 23664266; PMCID: PMC4601575.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    122. Metastatic pancreatic insulinoma with treatment-limiting thrombocytopenia. Am Surg. 2013 Mar; 79(3):E124-6. Nguyen AH, Donahue TR. PMID: 23461938.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    123. The evolving management of infected pancreatic necrosis. Am Surg. 2012 Oct; 78(10):1151-5. Donald G, Donahue T, Reber HA, Hines OJ. PMID: 23025961; PMCID: PMC3678520.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    124. HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma. Cancer. 2013 Feb 01; 119(3):529-39. Nguyen Kovochich A, Arensman M, Lay AR, Rao NP, Donahue T, Li X, French SW, Dawson DW. PMID: 22914903; PMCID: PMC3867310.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    125. Cell intrinsic role of COX-2 in pancreatic cancer development. Mol Cancer Ther. 2012 Oct; 11(10):2127-37. Hill R, Li Y, Tran LM, Dry S, Calvopina JH, Garcia A, Kim C, Wang Y, Donahue TR, Herschman HR, Wu H. PMID: 22784710; PMCID: PMC3469770.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    126. Integrative survival-based molecular profiling of human pancreatic cancer. Clin Cancer Res. 2012 Mar 01; 18(5):1352-63. Donahue TR, Tran LM, Hill R, Li Y, Kovochich A, Calvopina JH, Patel SG, Wu N, Hindoyan A, Farrell JJ, Li X, Dawson DW, Wu H. PMID: 22261810; PMCID: PMC3816537.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansCells
    127. T cell receptor transgenic lymphocytes infiltrating murine tumors are not induced to express foxp3. J Hematol Oncol. 2011 Nov 23; 4:48. Quatromoni JG, Morris LF, Donahue TR, Wang Y, McBride W, Chatila T, Economou JS. PMID: 22112546; PMCID: PMC3245424.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    128. Nodal/Activin signaling: a novel target for pancreatic cancer stem cell therapy. Cell Stem Cell. 2011 Nov 04; 9(5):383-4. Donahue TR, Dawson DW. PMID: 22056131.
      View in: PubMed   Mentions: 3     Fields:    
    129. Downstaging chemotherapy and alteration in the classic computed tomography/magnetic resonance imaging signs of vascular involvement in patients with pancreaticobiliary malignant tumors: influence on patient selection for surgery. Arch Surg. 2011 Jul; 146(7):836-43. Donahue TR, Isacoff WH, Hines OJ, Tomlinson JS, Farrell JJ, Bhat YM, Garon E, Clerkin B, Reber HA. PMID: 21768431.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    130. Operative blood loss and survival in pancreatic cancer. Pancreas. 2011 Jan; 40(1):1-2. Donahue TR, Reber HA. PMID: 21160368.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    131. Cystic neoplasms of the pancreas: results of 114 cases. Pancreas. 2010 Nov; 39(8):1271-6. Donahue TR, Hines OJ, Farrell JJ, Tomlinson JS, Eibl G, Reber HA. PMID: 20717069.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    132. Pancreatic surgery. Curr Opin Gastroenterol. 2010 Sep; 26(5):499-505. Donahue TR, Reber HA. PMID: 20651590.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    133. PTEN loss accelerates KrasG12D-induced pancreatic cancer development. Cancer Res. 2010 Sep 15; 70(18):7114-24. Hill R, Calvopina JH, Kim C, Wang Y, Dawson DW, Donahue TR, Dry S, Wu H. PMID: 20807812; PMCID: PMC2940963.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimals
    134. Evaluation of neoadjuvant therapy and histopathologic response in primary, high-grade retroperitoneal sarcomas using the sarcoma nomogram. Cancer. 2010 Aug 15; 116(16):3883-91. Donahue TR, Kattan MW, Nelson SD, Tap WD, Eilber FR, Eilber FC. PMID: 20564145.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    135. Impact of splenectomy on thrombocytopenia, chemotherapy, and survival in patients with unresectable pancreatic cancer. J Gastrointest Surg. 2010 Jun; 14(6):1012-8. Donahue TR, Kazanjian KK, Isacoff WH, Reber HA, Hines OJ. PMID: 20309646; PMCID: PMC2872015.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    136. The ZIP4 pathway in pancreatic cancer. Cancer Biol Ther. 2010 Feb; 9(3):243-5. Donahue T, Hines OJ. PMID: 20104017.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    137. Enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824. Cancer Res. 2009 Nov 15; 69(22):8693-9. Vo DD, Prins RM, Begley JL, Donahue TR, Morris LF, Bruhn KW, de la Rocha P, Yang MY, Mok S, Garban HJ, Craft N, Economou JS, Marincola FM, Wang E, Ribas A. PMID: 19861533; PMCID: PMC2779578.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    138. CXCR2 and RET single nucleotide polymorphisms in pancreatic cancer. World J Surg. 2009 Apr; 33(4):710-5. Donahue TR, Hines OJ. PMID: 19057948.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    139. Intratumoral immune cell infiltrates, FoxP3, and indoleamine 2,3-dioxygenase in patients with melanoma undergoing CTLA4 blockade. Clin Cancer Res. 2009 Jan 01; 15(1):390-9. Ribas A, Comin-Anduix B, Economou JS, Donahue TR, de la Rocha P, Morris LF, Jalil J, Dissette VB, Shintaku IP, Glaspy JA, Gomez-Navarro J, Cochran AJ. PMID: 19118070.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    140. Early versus delayed hormonal therapy for prostate specific antigen only recurrence of prostate cancer after radical prostatectomy. J Urol. 2008 May; 179(5 Suppl):S53-9. Moul JW, Wu H, Sun L, McLeod DG, Amling C, Donahue T, Kusuda L, Sexton W, O'Reilly K, Hernandez J, Chung A, Soderdahl D. PMID: 18405753.
      View in: PubMed   Mentions: 8     Fields:    
    141. Collagenase and surgical disease. Hernia. 2006 Dec; 10(6):478-85. Donahue TR, Hiatt JR, Busuttil RW. PMID: 16977344.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    142. Watchful waiting and factors predictive of secondary treatment of localized prostate cancer. J Urol. 2004 Mar; 171(3):1111-6. Wu H, Sun L, Moul JW, Wu HY, McLeod DG, Amling C, Lance R, Kusuda L, Donahue T, Foley J, Chung A, Sexton W, Soderdahl D. PMID: 14767282.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    143. Early versus delayed hormonal therapy for prostate specific antigen only recurrence of prostate cancer after radical prostatectomy. J Urol. 2004 Mar; 171(3):1141-7. Moul JW, Wu H, Sun L, McLeod DG, Amling C, Donahue T, Kusuda L, Sexton W, O'Reilly K, Hernandez J, Chung A, Soderdahl D. PMID: 14767288.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    144. Temporarily deferred therapy (watchful waiting) for men younger than 70 years and with low-risk localized prostate cancer in the prostate-specific antigen era. J Clin Oncol. 2003 Nov 01; 21(21):4001-8. Carter CA, Donahue T, Sun L, Wu H, McLeod DG, Amling C, Lance R, Foley J, Sexton W, Kusuda L, Chung A, Soderdahl D, Jackmaan S, Moul JW. PMID: 14581423.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    145. Factors associated with blood loss during radical prostatectomy for localized prostate cancer in the prostate-specific antigen (PSA)-era: an overview of the Department of Defense (DOD) Center for Prostate Disease Research (CPDR) national database. Urol Oncol. 2003 Nov-Dec; 21(6):447-55. Moul JW, Sun L, Wu H, McLeod DG, Amling C, Lance R, Foley J, Sexton W, Kusuda L, Chung A, Soderdahl D, Donahue T. PMID: 14693271.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    146. Pretreatment total testosterone level predicts pathological stage in patients with localized prostate cancer treated with radical prostatectomy. J Urol. 2003 May; 169(5):1670-5. Massengill JC, Sun L, Moul JW, Wu H, McLeod DG, Amling C, Lance R, Foley J, Sexton W, Kusuda L, Chung A, Soderdahl D, Donahue T. PMID: 12686805.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    147. Effect of age on biochemical disease-free outcome in patients with T1-T3 prostate cancer treated with definitive radiotherapy in an equal-access health care system: a radiation oncology report of the Department of Defense Center for Prostate Disease Research. Int J Radiat Oncol Biol Phys. 2003 Mar 15; 55(4):964-9. Johnstone PA, Riffenburgh RH, Moul JW, Sun L, Wu H, McLeod DG, Kane CJ, Martin DD, Kusuda L, Lance R, Douglas R, Donahue T, Beat MG, Foley J, Chung A, Soderdahl D, Do J, Amling CL, Department of Defense Center for Prostate Disease Research. PMID: 12605974.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    148. Epidemiology of radical prostatectomy for localized prostate cancer in the era of prostate-specific antigen: an overview of the Department of Defense Center for Prostate Disease Research national database. Surgery. 2002 Aug; 132(2):213-9. Moul JW, Wu H, Sun L, McLeod DG, Amling C, Lance R, Kusuda L, Donahue T, Foley J, Chung A, Sexton W, Soderdahl D, Rich NM. PMID: 12219014.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
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