Joseph R Pisegna

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
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    Other Positions
    Title(s)Professor-in-Residence, Human Genetics


    Collapse Research 
    Collapse Research Activities and Funding
    ShEEP Request for Acquisition a 10x Genomics Single Cell RNA Sequencer
    NIH IS1BX005025Sep 1, 2019 - Sep 30, 2020
    Role: Principal Investigator
    CMA: Cancer Stem Cells in the Pathogenesis and Treatment of Colorectal Cancer
    NIH I01BX004560Apr 1, 2019 - Mar 31, 2023
    Role: Principal Investigator
    Gastrointestinal Hormonal Regulation of Obesity
    NIH I01RX000194Oct 1, 2010 - Sep 30, 2015
    Role: Principal Investigator
    LOCALIZATION/SIGNAL TRANSDUCTION
    NIH R03DK052274Sep 30, 1996 - Aug 31, 1998
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Human liver single nucleus and single cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival. Genome Med. 2022 05 17; 14(1):50. Alvarez M, Benhammou JN, Darci-Maher N, French SW, Han SB, Sinsheimer JS, Agopian VG, Pisegna JR, Pajukanta P. PMID: 35581624; PMCID: PMC9115949.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    2. The VIP/VPAC1R Pathway Regulates Energy and Glucose Homeostasis by Modulating GLP-1, Glucagon, Leptin and PYY Levels in Mice. Biology (Basel). 2022 Mar 11; 11(3). Sanford D, Luong L, Vu JP, Oh S, Gabalski A, Lewis M, Pisegna JR, Germano P. PMID: 35336804; PMCID: PMC8945135.
      View in: PubMed   Mentions: 1  
    3. β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development. Sci Transl Med. 2021 12 15; 13(624):eabk2267. Rao S, Yang X, Ohshiro K, Zaidi S, Wang Z, Shetty K, Xiang X, Hassan MI, Mohammad T, Latham PS, Nguyen BN, Wong L, Yu H, Al-Abed Y, Mishra B, Vacca M, Guenigault G, Allison MED, Vidal-Puig A, Benhammou JN, Alvarez M, Pajukanta P, Pisegna JR, Mishra L. PMID: 34910547; PMCID: PMC8941321.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    4. Duodenal Microbiome and Serum Metabolites Predict Hepatocellular Carcinoma in a Multicenter Cohort of Patients with Cirrhosis. Dig Dis Sci. 2022 08; 67(8):3831-3841. Dong TS, Jacobs JP, Agopian V, Pisegna JR, Ayoub W, Durazo F, Enayati P, Sundaram V, Benhammou JN, Noureddin M, Choi G, Lagishetty V, Fiehn O, Goodman MT, Elashoff D, Hussain SK. PMID: 34799768; PMCID: PMC9287237.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Prediction of Pancreatic Cancer in Diabetes Patients with Worsening Glycemic Control. Cancer Epidemiol Biomarkers Prev. 2022 01; 31(1):242-253. Jeon CY, Kim S, Lin YC, Risch HA, Goodarzi MO, Nuckols TK, Freedland SJ, Pandol SJ, Pisegna JR. PMID: 34728468; PMCID: PMC8759109.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Longitudinal Changes in Liver Enzyme Levels Among Transgender People Receiving Gender Affirming Hormone Therapy. J Sex Med. 2021 09; 18(9):1662-1675. Hashemi L, Zhang Q, Getahun D, Jasuja GK, McCracken C, Pisegna J, Roblin D, Silverberg MJ, Tangpricha V, Vupputuri S, Goodman M. PMID: 34366264; PMCID: PMC8444147.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. The Intestinal Microbiome Predicts Weight Loss on a Calorie-Restricted Diet and Is Associated With Improved Hepatic Steatosis. Front Nutr. 2021; 8:718661. Dong TS, Luu K, Lagishetty V, Sedighian F, Woo SL, Dreskin BW, Katzka W, Chang C, Zhou Y, Arias-Jayo N, Yang J, Ahdoot AI, Ye J, Li Z, Pisegna JR, Jacobs JP. PMID: 34307440; PMCID: PMC8295485.
      View in: PubMed   Mentions: 4  
    8. A Case-CrossovEr study deSign to inform tailored interventions to prevent disease progression in Acute Pancreatitis (ACCESS-AP) - study design and population. Pancreatology. 2021 Oct; 21(7):1231-1236. Jeon CY, Papachristou GI, Pisegna JR, Pendergast FJ, Lin YC, Cherpitel CJ, Ye Y, Pandol SJ, Yadav D. PMID: 34229971.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    9. Specimen Collection and Analysis of the Duodenal Microbiome. J Vis Exp. 2021 01 12; (167). Dreskin BW, Luu K, Dong TS, Benhammou J, Lagishetty V, Vu J, Sanford D, Durazo F, Agopian VG, Jacobs JP, Pisegna JR, Hussain SK. PMID: 33522511.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. A High Protein Calorie Restriction Diet Alters the Gut Microbiome in Obesity. Nutrients. 2020 Oct 21; 12(10). Dong TS, Luu K, Lagishetty V, Sedighian F, Woo SL, Dreskin BW, Katzka W, Chang C, Zhou Y, Arias-Jayo N, Yang J, Ahdoot A, Li Z, Pisegna JR, Jacobs JP. PMID: 33096810; PMCID: PMC7590138.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    11. Three Cases of Diffuse, Intense Stomach Uptake on DOTATATE PET. Clin Nucl Med. 2020 Oct; 45(10):813-816. Auerbach MS, Pisegna JR, Kim S, Yu R. PMID: 32604111.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    12. Editorial: tegoprazan-the newest advance in the management of acid-related diseases. Aliment Pharmacol Ther. 2020 09; 52(6):1074-1075. Marcus EA, Pisegna JR. PMID: 33119154.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Nonalcoholic Fatty Liver Disease Risk Factors Affect Liver-Related Outcomes After Direct-Acting Antiviral Treatment for Hepatitis C. Dig Dis Sci. 2021 07; 66(7):2394-2406. Benhammou JN, Moon AM, Pisegna JR, Su F, Vutien P, Moylan CA, Ioannou GN. PMID: 32654086; PMCID: PMC7854862.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    14. Enhancing droplet-based single-nucleus RNA-seq resolution using the semi-supervised machine learning classifier DIEM. Sci Rep. 2020 07 03; 10(1):11019. Alvarez M, Rahmani E, Jew B, Garske KM, Miao Z, Benhammou JN, Ye CJ, Pisegna JR, Pietiläinen KH, Halperin E, Pajukanta P. PMID: 32620816; PMCID: PMC7335186.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    15. Dietary Protein, Fiber and Coffee Are Associated with Small Intestine Microbiome Composition and Diversity in Patients with Liver Cirrhosis. Nutrients. 2020 May 13; 12(5). Hussain SK, Dong TS, Agopian V, Pisegna JR, Durazo FA, Enayati P, Sundaram V, Benhammou JN, Noureddin M, Choi G, Ayoub WS, Lagishetty V, Elashoff D, Goodman MT, Jacobs JP. PMID: 32414035; PMCID: PMC7285216.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. A Telephone and Mail Outreach Program Successfully Increases Uptake of Hepatocellular Carcinoma Surveillance. Hepatol Commun. 2020 Jun; 4(6):825-833. Aby ES, Winters AC, Lin J, Bui A, Kawamoto J, Goetz MB, Bhattacharya D, Pisegna JR, May FP, Patel AA, Benhammou JN. PMID: 32490319; PMCID: PMC7262281.
      View in: PubMed   Mentions: 2     Fields:    
    17. A Microbial Signature Identifies Advanced Fibrosis in Patients with Chronic Liver Disease Mainly Due to NAFLD. Sci Rep. 2020 02 17; 10(1):2771. Dong TS, Katzka W, Lagishetty V, Luu K, Hauer M, Pisegna J, Jacobs JP. PMID: 32066758; PMCID: PMC7026172.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    18. Intraperitoneal Treatment of Kisspeptin Suppresses Appetite and Energy Expenditure and Alters Gastrointestinal Hormones in Mice. Dig Dis Sci. 2020 08; 65(8):2254-2263. Dong TS, Vu JP, Oh S, Sanford D, Pisegna JR, Germano P. PMID: 31729619.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    19. Baseline human gut microbiota profile in healthy people and standard reporting template. PLoS One. 2019; 14(9):e0206484. King CH, Desai H, Sylvetsky AC, LoTempio J, Ayanyan S, Carrie J, Crandall KA, Fochtman BC, Gasparyan L, Gulzar N, Howell P, Issa N, Krampis K, Mishra L, Morizono H, Pisegna JR, Rao S, Ren Y, Simonyan V, Smith K, VedBrat S, Yao MD, Mazumder R. PMID: 31509535; PMCID: PMC6738582.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    20. Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation-Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl-Coenzyme A Desaturase As an Enhancer RNA. Hepatol Commun. 2019 Oct; 3(10):1356-1372. Benhammou JN, Ko A, Alvarez M, Kaikkonen MU, Rankin C, Garske KM, Padua D, Bhagat Y, Kaminska D, Kärjä V, Pihlajamäki J, Pisegna JR, Pajukanta P. PMID: 31592021; PMCID: PMC6771395.
      View in: PubMed   Mentions: 15     Fields:    
    21. Magnetic resonance imaging as a non-invasive method for the assessment of pancreatic fibrosis (MINIMAP): a comprehensive study design from the consortium for the study of chronic pancreatitis, diabetes, and pancreatic cancer. Abdom Radiol (NY). 2019 08; 44(8):2809-2821. Tirkes T, Yadav D, Conwell DL, Territo PR, Zhao X, Venkatesh SK, Kolipaka A, Li L, Pisegna JR, Pandol SJ, Park WG, Topazian M, Serrano J, Fogel EL, Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. PMID: 31089778; PMCID: PMC6599731.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    22. Correction to: PACAP/PAC1 Regulation of Inflammation via Catecholaminergic Neurons in a Model of Multiple Sclerosis. J Mol Neurosci. 2019 07; 68(3):452. Van C, Condro MC, Lov K, Zhu R, Ricaflanca PT, Ko HH, Diep AL, Hoang AQ, Pisegna J, Rohrer H, Waschek JA. PMID: 30362069; PMCID: PMC6873810.
      View in: PubMed   Mentions: 1     Fields:    
    23. Do changes in health reveal the possibility of undiagnosed pancreatic cancer? Development of a risk-prediction model based on healthcare claims data. PLoS One. 2019; 14(6):e0218580. Baecker A, Kim S, Risch HA, Nuckols TK, Wu BU, Hendifar AE, Pandol SJ, Pisegna JR, Jeon CY. PMID: 31237889; PMCID: PMC6592596.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Reverse gene-environment interaction approach to identify variants influencing body-mass index in humans. Nat Metab. 2019 06; 1(6):630-642. Garske KM, Pan DZ, Miao Z, Bhagat YV, Comenho C, Robles CR, Benhammou JN, Alvarez M, Ko A, Ye CJ, Pisegna JR, Mohlke KL, Sinsheimer JS, Laakso M, Pajukanta P. PMID: 31538139; PMCID: PMC6752726.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    25. Generalized Cytokine Increase in the Setting of a Multisystem Clinical Disorder and Carcinoid Syndrome Associated with a Novel NLRP12 Variant. Dig Dis Sci. 2019 08; 64(8):2140-2146. Jacob N, Dasharathy SS, Bui V, Benhammou JN, Grody WW, Singh RR, Pisegna JR. PMID: 30788684; PMCID: PMC6707534.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    26. An Intraperitoneal Treatment with Calcitonin Gene-Related Peptide (CGRP) Regulates Appetite, Energy Intake/Expenditure, and Metabolism. J Mol Neurosci. 2019 Jan; 67(1):28-37. Sanford D, Luong L, Gabalski A, Oh S, Vu JP, Pisegna JR, Germano P. PMID: 30535790; PMCID: PMC6736536.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    27. Passing the "Acid Test": Do Proton Pump Inhibitors Affect the Composition of the Microbiome? Dig Dis Sci. 2018 11; 63(11):2817-2819. Dong T, Pisegna J. PMID: 30218426; PMCID: PMC6408263.
      View in: PubMed   Mentions: 1     Fields:    
    28. A Prognostic Scoring System for the Prediction of Metastatic Recurrence Following Curative Resection of Pancreatic Neuroendocrine Tumors. J Gastrointest Surg. 2019 07; 23(7):1392-1400. Sho S, Court CM, Winograd P, Toste PA, Pisegna JR, Lewis M, Donahue TR, Hines OJ, Reber HA, Dawson DW, Tomlinson JS. PMID: 30353489; PMCID: PMC6736531.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    29. Metabolic syndrome does not affect sustained virologic response of direct-acting antivirals while hepatitis C clearance improves hemoglobin A1c. World J Hepatol. 2018 Sep 27; 10(9):612-621. Dong TS, Aby ES, Benhammou JN, Kawamoto J, Han SH, May FP, Pisegna JR. PMID: 30310539; PMCID: PMC6177571.
      View in: PubMed   Mentions: 6  
    30. PACAP/PAC1 Regulation of Inflammation via Catecholaminergic Neurons in a Model of Multiple Sclerosis. J Mol Neurosci. 2019 Jul; 68(3):439-451. Van C, Condro MC, Lov K, Zhu R, Ricaflanca PT, Ko HH, Diep AL, Hoang AQ, Pisegna J, Rohrer H, Waschek JA. PMID: 30058008; PMCID: PMC6353700.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    31. Microbiome and bile acid profiles in duodenal aspirates from patients with liver cirrhosis: The Microbiome, Microbial Markers and Liver Disease Study. Hepatol Res. 2018 Dec; 48(13):1108-1117. Jacobs JP, Dong TS, Agopian V, Lagishetty V, Sundaram V, Noureddin M, Ayoub WS, Durazo F, Benhammou J, Enayati P, Elashoff D, Goodman MT, Pisegna J, Hussain S. PMID: 29923681; PMCID: PMC6334634.
      View in: PubMed   Mentions: 15  
    32. Prevalence of Panoramically Imaged Carotid Atheromas in Alcoholic Patients With Chronic Pancreatitis and Comorbid Diabetes. J Oral Maxillofac Surg. 2018 09; 76(9):1929.e1-1929.e7. Lee UK, Chang TI, Polanco JC, Pisegna JR, Friedlander AH. PMID: 29859950; PMCID: PMC6707531.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions. Dig Dis Sci. 2018 05; 63(5):1123-1138. Mohapatra SS, Batra SK, Bharadwaj S, Bouvet M, Cosman B, Goel A, Jogunoori W, Kelley MJ, Mishra L, Mishra B, Mohapatra S, Patel B, Pisegna JR, Raufman JP, Rao S, Roy H, Scheuner M, Singh S, Vidyarthi G, White J. PMID: 29572615; PMCID: PMC5895694.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Race affects SVR12 in a large and ethnically diverse hepatitis C-infected patient population following treatment with direct-acting antivirals: Analysis of a single-center Department of Veterans Affairs cohort. Pharmacol Res Perspect. 2018 04; 6(2):e00379. Benhammou JN, Dong TS, May FP, Kawamoto J, Dixit R, Jackson S, Dixit V, Bhattacharya D, Han SB, Pisegna JR. PMID: 29484189; PMCID: PMC5821896.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    35. A Challenging Case of Severe Ulcerative Colitis following the Initiation of Secukinumab for Ankylosing Spondylitis. Case Rep Gastrointest Med. 2018; 2018:9679287. Ehrlich D, Jamaluddin N, Pisegna J, Padua D. PMID: 29666723; PMCID: PMC5832071.
      View in: PubMed   Mentions: 11  
    36. Impact of sustained virologic response on chronic kidney disease progression in hepatitis C. World J Hepatol. 2017 Dec 28; 9(36):1352-1360. Aby ES, Dong TS, Kawamoto J, Pisegna JR, Benhammou JN. PMID: 29359019; PMCID: PMC5756725.
      View in: PubMed   Mentions: 8  
    37. Long-Term Intake of a High-Protein Diet Affects Body Phenotype, Metabolism, and Plasma Hormones in Mice. J Nutr. 2017 12; 147(12):2243-2251. Vu JP, Luong L, Parsons WF, Oh S, Sanford D, Gabalski A, Lighton JR, Pisegna JR, Germano PM. PMID: 29070713; PMCID: PMC5697971.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    38. Gastrointestinal Manifestations of Hereditary Hemorrhagic Telangiectasia (HHT): A Systematic Review of the Literature. Dig Dis Sci. 2017 10; 62(10):2623-2630. Jackson SB, Villano NP, Benhammou JN, Lewis M, Pisegna JR, Padua D. PMID: 28836046; PMCID: PMC5641264.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    39. The Gastric and Intestinal Microbiome: Role of Proton Pump Inhibitors. Curr Gastroenterol Rep. 2017 Aug; 19(8):42. Minalyan A, Gabrielyan L, Scott D, Jacobs J, Pisegna JR. PMID: 28733944; PMCID: PMC5621514.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    40. High-protein diet improves sensitivity to cholecystokinin and shifts the cecal microbiome without altering brain inflammation in diet-induced obesity in rats. Am J Physiol Regul Integr Comp Physiol. 2017 Oct 01; 313(4):R473-R486. Wang L, Jacobs JP, Lagishetty V, Yuan PQ, Wu SV, Million M, Reeve JR, Pisegna JR, Taché Y. PMID: 28724546; PMCID: PMC5668619.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    41. Most of the Intended Management Changes After 68Ga-DOTATATE PET/CT Are Implemented. J Nucl Med. 2017 11; 58(11):1793-1796. Calais J, Czernin J, Eiber M, Fendler WP, Gartmann J, Heaney AP, Hendifar AE, Pisegna JR, Hecht JR, Wolin EM, Slavik R, Gupta P, Quon A, Schiepers C, Allen-Auerbach MS, Herrmann K. PMID: 28473600; PMCID: PMC5666645.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    42. Endoscopic Ultrasound-Guided Fine Needle Aspiration Accurately Diagnoses Smaller Pancreatic Neuroendocrine Tumors Compared To Computer Tomography-Guided Fine Needle Aspiration. J Gastroenterol Pancreatol Liver Disord. 2017; 4(2):1-7. Wang J, Benhammou JN, Ghassemi K, Kim S, Sedarat A, Farrell J, Pisegna JR. PMID: 29516037; PMCID: PMC5837075.
      View in: PubMed   Mentions:
    43. Ambient Ultrafine Particle Ingestion Alters Gut Microbiota in Association with Increased Atherogenic Lipid Metabolites. Sci Rep. 2017 02 17; 7:42906. Li R, Yang J, Saffari A, Jacobs J, Baek KI, Hough G, Larauche MH, Ma J, Jen N, Moussaoui N, Zhou B, Kang H, Reddy S, Henning SM, Campen MJ, Pisegna J, Li Z, Fogelman AM, Sioutas C, Navab M, Hsiai TK. PMID: 28211537; PMCID: PMC5314329.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    44. Autoimmune atrophic gastritis: current perspectives. Clin Exp Gastroenterol. 2017; 10:19-27. Minalyan A, Benhammou JN, Artashesyan A, Lewis MS, Pisegna JR. PMID: 28223833; PMCID: PMC5304992.
      View in: PubMed   Mentions: 41  
    45. A Sodium Channel Myotonia Presenting with Intermittent Dysphagia as a Manifestation of a Rare SCN4A Variant. J Mol Neurosci. 2017 Mar; 61(3):312-314. Benhammou JN, Phan J, Lee H, Ghassemi K, Parsons W, Grody WW, Pisegna JR. PMID: 28012096; PMCID: PMC5346050.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    46. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. Am J Physiol Gastrointest Liver Physiol. 2016 09 01; 311(3):G446-57. Padua D, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih D, Iliopoulos D, Pothoulakis C. PMID: 27492330; PMCID: PMC5076004.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    47. The Role of Neuropeptides in Mouse Models of Colitis. J Mol Neurosci. 2016 Jun; 59(2):203-10. Padua D, Vu JP, Germano PM, Pisegna JR. PMID: 26646243; PMCID: PMC4884658.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    48. Gastric Hypersecretory States: Investigation and Management. Curr Treat Options Gastroenterol. 2015 Dec; 13(4):386-97. Phan J, Benhammou JN, Pisegna JR. PMID: 26342486; PMCID: PMC4633316.
      View in: PubMed   Mentions: 12  
    49. PACAP intraperitoneal treatment suppresses appetite and food intake via PAC1 receptor in mice by inhibiting ghrelin and increasing GLP-1 and leptin. Am J Physiol Gastrointest Liver Physiol. 2015 Nov 15; 309(10):G816-25. Vu JP, Goyal D, Luong L, Oh S, Sandhu R, Norris J, Parsons W, Pisegna JR, Germano PM. PMID: 26336928; PMCID: PMC4652141.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    50. Regulation of Appetite, Body Composition, and Metabolic Hormones by Vasoactive Intestinal Polypeptide (VIP). J Mol Neurosci. 2015 Jun; 56(2):377-87. Vu JP, Larauche M, Flores M, Luong L, Norris J, Oh S, Liang LJ, Waschek J, Pisegna JR, Germano PM. PMID: 25904310; PMCID: PMC4458420.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    51. Inhibition of vasoactive intestinal polypeptide (VIP) induces resistance to dextran sodium sulfate (DSS)-induced colitis in mice. J Mol Neurosci. 2014 Jan; 52(1):37-47. Vu JP, Million M, Larauche M, Luong L, Norris J, Waschek JA, Pothoulakis C, Pisegna JR, Germano PM. PMID: 24395090; PMCID: PMC4114158.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    52. High-protein diet selectively reduces fat mass and improves glucose tolerance in Western-type diet-induced obese rats. Am J Physiol Regul Integr Comp Physiol. 2013 Sep 15; 305(6):R582-91. Stengel A, Goebel-Stengel M, Wang L, Hu E, Karasawa H, Pisegna JR, Tach? Y. PMID: 23883680; PMCID: PMC3763043.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    53. Adenoma detection rate is necessary but insufficient for distinguishing high versus low endoscopist performance. Gastrointest Endosc. 2013 Jan; 77(1):71-8. Wang HS, Pisegna J, Modi R, Liang LJ, Atia M, Nguyen M, Cohen H, Ohning G, van Oijen M, Spiegel BM. PMID: 23261096.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    54. Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1. Br J Pharmacol. 2012 May; 166(1):4-17. Harmar AJ, Fahrenkrug J, Gozes I, Laburthe M, May V, Pisegna JR, Vaudry D, Vaudry H, Waschek JA, Said SI. PMID: 22289055; PMCID: PMC3415633.
      View in: PubMed   Mentions: 183     Fields:    Translation:HumansAnimals
    55. Ghrelin in neuroendocrine tumors. Peptides. 2011 Nov; 32(11):2340-7. Vu JP, Wang HS, Germano PM, Pisegna JR. PMID: 22041110; PMCID: PMC6707517.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    56. Clinical trial report: Eradication of Helicobacter pylori reduces the risk for subsequent gastric cancer. Curr Gastroenterol Rep. 2010 Dec; 12(6):427-30. Pisegna JR, Surti B, Scott DR. PMID: 20857239; PMCID: PMC2974208.
      View in: PubMed   Mentions: 1     Fields:    
    57. PAC1 deficiency in a murine model induces gastric mucosa hypertrophy and higher basal gastric acid output. J Mol Neurosci. 2011 Jan; 43(1):76-84. Lu Y, Germano P, Ohning GV, Vu JP, Pisegna JR. PMID: 20821075; PMCID: PMC3018609.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    58. Do COX-2 inhibitors reduce metachronous cancer development? Curr Gastroenterol Rep. 2009 Dec; 11(6):429-30. Pisegna JR. PMID: 19903417.
      View in: PubMed   Mentions:    Fields:    
    59. PACAP induces signaling and stimulation of 5-hydroxytryptamine release and growth in neuroendocrine tumor cells. J Mol Neurosci. 2009 Nov; 39(3):391-401. Germano PM, Lieu SN, Xue J, Cooke HJ, Christofi FL, Lu Y, Pisegna JR. PMID: 19701709; PMCID: PMC6736522.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    60. Duodenal bulb mucosa with hypertrophic gastric oxyntic heterotopia in patients with zollinger ellison syndrome. Diagn Ther Endosc. 2009; 2009:298381. Kohan E, Oh D, Wang H, Hazany S, Ohning G, Pisegna JR. PMID: 19587828; PMCID: PMC2705831.
      View in: PubMed   Mentions: 3  
    61. Is surveillance upper endoscopy indicated for gastric ulcers? Curr Gastroenterol Rep. 2008 Dec; 10(6):521-2. Pisegna JR. PMID: 19006604.
      View in: PubMed   Mentions:    Fields:    
    62. Effect of preoperative intravenous pantoprazole in elective-surgery patients: a pilot study. Dig Dis Sci. 2009 May; 54(5):1041-9. Pisegna JR, Karlstadt RG, Norton JA, Fogel R, Oh DS, Jay Graepel G, Dorr MB. PMID: 18754096; PMCID: PMC6736543.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    63. Comparative efficacy of rabeprazole and pantoprazole in the control of nocturnal Acid output and intragastric acidity. Gut Liver. 2008 Jun; 2(1):30-8. Wang HS, Oh DS, Anderson A, Nieto J, Tien P, Ohning G, Pisegna JR. PMID: 20485608; PMCID: PMC2871576.
      View in: PubMed   Mentions: 1     Fields:    
    64. Intravenous esomeprazole 40 mg vs. intravenous lansoprazole 30 mg for controlling intragastric acidity in healthy adults. Aliment Pharmacol Ther. 2008 Mar 15; 27(6):483-90. Pisegna JR, Sostek MB, Monyak JT, Miner PB. PMID: 18162083; PMCID: PMC6736538.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    65. Effects of esomeprazole on acid output in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion. Am J Gastroenterol. 2007 Dec; 102(12):2648-54. Metz DC, Sostek MB, Ruszniewski P, Forsmark CE, Monyak J, Pisegna JR. PMID: 17764495.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    66. Elevated serum ghrelin exerts an orexigenic effect that may maintain body mass index in patients with metastatic neuroendocrine tumors. J Mol Neurosci. 2007; 33(3):225-31. Wang HS, Oh DS, Ohning GV, Pisegna JR. PMID: 17952631; PMCID: PMC6736537.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    67. Pituitary adenylate cyclase-activating polypeptide: a novel peptide with protean implications. Curr Opin Endocrinol Diabetes Obes. 2007 Feb; 14(1):58-62. Pisegna JR, Oh DS. PMID: 17940421; PMCID: PMC6736533.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    68. Cyto-reduction of neuroendocrine tumours using Sandostatin LAR in combination with Infergen: results of a case series. J Pharm Pharmacol. 2006 Dec; 58(12):1623-8. Wang HS, Oh DS, Ohning GV, Pisegna JR. PMID: 17331326; PMCID: PMC6736541.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    69. Validation of a new endoscopic technique to assess acid output in Zollinger-Ellison syndrome. Clin Gastroenterol Hepatol. 2006 Dec; 4(12):1467-73. Oh DS, Wang HS, Ohning GV, Pisegna JR. PMID: 17101299; PMCID: PMC6736528.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    70. Neuroendocrine tumors express PAC1 receptors. Ann N Y Acad Sci. 2006 Jul; 1070:399-404. Lieu SN, Oh DS, Pisegna JR, Germano PM. PMID: 16888199; PMCID: PMC6719703.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    71. The role of proton pump inhibitors in the treatment of Zollinger-Ellison syndrome. Expert Opin Pharmacother. 2006 Feb; 7(2):169-75. Nieto JM, Pisegna JR. PMID: 16433582.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    72. Rabeprazole controls GERD symptoms in a patient for whom treatment with lansoprazole failed: first report of "cluster GERD.". Dig Dis Sci. 2005 May; 50(5):853-7. Oh DS, Ohning GV, Pisegna JR. PMID: 15912621; PMCID: PMC6719682.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    73. Acid suppression in the perioperative period. J Clin Gastroenterol. 2005 Jan; 39(1):10-6. Pisegna JR, Martindale RG. PMID: 15599203.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    74. PACAP regulation of secretion and proliferation of pure populations of gastric ECL cells. J Mol Neurosci. 2005; 26(1):85-97. Oh DS, Lieu SN, Yamaguchi DJ, Tachiki K, Lambrecht N, Ohning GV, Sachs G, Germano PM, Pisegna JR. PMID: 15968088; PMCID: PMC6719686.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    75. Review article: oesophageal complications and consequences of persistent gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2004 Dec; 20 Suppl 9:47-56. Pisegna J, Holtmann G, Howden CW, Katelaris PH, Sharma P, Spechler S, Triadafilopoulos G, Tytgat G. PMID: 15527464; PMCID: PMC6736593.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    76. Reflux laryngitis in a patient with Zollinger Ellison syndrome and the role of epidermal growth factor. Dig Dis Sci. 2004 Apr; 49(4):693-6. Weinberg BM, Oh DS, Ohning GV, Pisegna JR. PMID: 15185880; PMCID: PMC6736585.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    77. Differential coupling of the PAC1 SV1 splice variant on human colonic tumors to the activation of intracellular cAMP but not intracellular Ca2+ does not activate tumor proliferation. J Mol Neurosci. 2004; 22(1-2):83-92. Germano PM, Le SV, Oh DS, Fan R, Lieu S, Siu A, Pisegna JR. PMID: 14742913; PMCID: PMC6707513.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    78. Treating patients with acute gastrointestinal bleeding or rebleeding. Pharmacotherapy. 2003 Oct; 23(10 Pt 2):81S-86S. Pisegna JR. PMID: 14587962.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    79. Alcohol abuse and dependence: psychopathology, medical management and dental implications. J Am Dent Assoc. 2003 Jun; 134(6):731-40. Friedlander AH, Marder SR, Pisegna JR, Yagiela JA. PMID: 12839410; PMCID: PMC6736549.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    80. Pharmacologic Treatment of Upper Gastrointestinal Bleeding. Curr Treat Options Gastroenterol. 2003 Apr; 6(2):157-162. Oh DS, Pisegna JR. PMID: 12628074; PMCID: PMC6746337.
      View in: PubMed   Mentions:
    81. Maintenance oral pantoprazole therapy is effective for patients with Zollinger-Ellison syndrome and idiopathic hypersecretion. Am J Gastroenterol. 2003 Feb; 98(2):301-7. Metz DC, Soffer E, Forsmark CE, Cryer B, Chey W, Bochenek W, Pisegna JR. PMID: 12591045.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    82. PAC1 and PACAP expression, signaling, and effect on the growth of HCT8, human colonic tumor cells. Regul Pept. 2002 Nov 15; 109(1-3):115-25. Le SV, Yamaguchi DJ, McArdle CA, Tachiki K, Pisegna JR, Germano P. PMID: 12409223; PMCID: PMC6736540.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    83. PACAP-27 tyrosine phosphorylates mitogen activated protein kinase and increases VEGF mRNAs in human lung cancer cells. Regul Pept. 2002 Nov 15; 109(1-3):135-40. Moody TW, Leyton J, Casibang M, Pisegna J, Jensen RT. PMID: 12409225; PMCID: PMC6736550.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    84. Pharmacology of acid suppression in the hospital setting: focus on proton pump inhibition. Crit Care Med. 2002 Jun; 30(6 Suppl):S356-61. Pisegna JR. PMID: 12072661; PMCID: PMC6736586.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    85. Expression of pituitary adenylate cyclase-activating polypeptide and PACAP type 1 receptor in the rat gastric and colonic myenteric neurons. Regul Pept. 2002 May 30; 105(3):145-54. Miampamba M, Germano PM, Arli S, Wong HH, Scott D, Taché Y, Pisegna JR. PMID: 11959368; PMCID: PMC6736535.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    86. Proton pump activation in stimulated parietal cells is regulated by gastric acid secretory capacity: a human study. J Clin Pharmacol. 2002 May; 42(5):512-9. Metz DC, Ferron GM, Paul J, Turner MB, Soffer E, Pisegna JR, Bochenek WJ. PMID: 12017345; PMCID: PMC6719691.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    87. Paraesophageal hernia repair and deep vein thrombosis. J Clin Gastroenterol. 2002 Feb; 34(2):187-8. Tang SJ, Tran T, Memmesheimer C, Pandol S, Aranda R, Pisegna JR, Jensen DM. PMID: 11782617.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    88. The novel use of an intravenous proton pump inhibitor in a patient with short bowel syndrome. J Clin Gastroenterol. 2002 Jan; 34(1):62-3. Tang SJ, Nieto JM, Jensen DM, Ohning GV, Pisegna JR. PMID: 11743248; PMCID: PMC6736583.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    89. GERD and its complications. The pathogenic relationship between symptoms and disease progression. Postgrad Med. 2001 Oct; Spec No:19-23. Pisegna JR. PMID: 11868427.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    90. Switching between intravenous and oral pantoprazole. J Clin Gastroenterol. 2001 Jan; 32(1):27-32. Pisegna JR. PMID: 11154164; PMCID: PMC6746342.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    91. Role of PACAP1 receptor in regulation of ECL cells and gastric acid secretion by pituitary adenylate cyclase activating peptide. Ann N Y Acad Sci. 2000; 921:233-41. Pisegna JR, Ohning GV, Athmann C, Zeng N, Walsh JH, Sachs G. PMID: 11193828; PMCID: PMC6736551.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    92. Essential structural motif in the C-terminus of the PACAP type I receptor for signal transduction and internalization. Ann N Y Acad Sci. 2000; 921:195-201. Pisegna JR, Lyu RM, Germano PM. PMID: 11193823.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
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