Aurelia Lugea

Title(s)Associate Adjunct Professor, Medicine
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Low dosage combination treatment with metformin and simvastatin inhibits obesity-promoted pancreatic cancer development in male KrasG12D mice. Sci Rep. 2023 09 26; 13(1):16144. Teper Y, Ye L, Waldron RT, Lugea A, Sun X, Sinnett-Smith J, Hines OJ, Pandol SJ, Rozengurt E, Eibl G. PMID: 37752238; PMCID: PMC10522691.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Salivary Biomarker Evaluation of Chronic Pancreatitis Patients Reveals Alterations in Human Proteins, Cytokines, Prostaglandin E2 Levels, and Bacterial Diversity. Pancreas. 2022 08 01; 51(7):723-732. Waldron RT, Jones EK, Anani VI, Hines JM, Zhao J, Lugea A, Diniz MA, Kim S, Habtezion A, Hoffman KL, Petrosino JF, Fisher WE, Li L, Lennon RJ, Singh RJ, Vege SS, Pandol SJ, Topazian MD. PMID: 36395395; PMCID: PMC9681020.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. The unique pancreatic stellate cell gene expression signatures are associated with the progression from acute to chronic pancreatitis. Comput Struct Biotechnol J. 2021; 19:6375-6385. Hu C, Yin L, Chen Z, Waldron RT, Lugea A, Lin Y, Zhai X, Wen L, Han YP, Pandol SJ, Deng L, Xia Q. PMID: 34938413; PMCID: PMC8649580.
      View in: PubMed   Mentions: 4  
    4. Pathological Mechanisms in Diabetes of the Exocrine Pancreas: What's Known and What's to Know. Front Physiol. 2020; 11:570276. Wei Q, Qi L, Lin H, Liu D, Zhu X, Dai Y, Waldron RT, Lugea A, Goodarzi MO, Pandol SJ, Li L. PMID: 33250773; PMCID: PMC7673428.
      View in: PubMed   Mentions: 10  
    5. Deficient Endoplasmic Reticulum Acetyl-CoA Import in Pancreatic Acinar Cells Leads to Chronic Pancreatitis. Cell Mol Gastroenterol Hepatol. 2021; 11(3):725-738. Cooley MM, Thomas DDH, Deans K, Peng Y, Lugea A, Pandol SJ, Puglielli L, Groblewski GE. PMID: 33080365; PMCID: PMC7841443.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    6. Critical thresholds: key to unlocking the door to the prevention and specific treatments for acute pancreatitis. Gut. 2021 01; 70(1):194-203. Barreto SG, Habtezion A, Gukovskaya A, Lugea A, Jeon C, Yadav D, Hegyi P, Venglovecz V, Sutton R, Pandol SJ. PMID: 32973069; PMCID: PMC7816970.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    7. Targeting the CBP/β-Catenin Interaction to Suppress Activation of Cancer-Promoting Pancreatic Stellate Cells. Cancers (Basel). 2020 Jun 05; 12(6). Che M, Kweon SM, Teo JL, Yuan YC, Melstrom LG, Waldron RT, Lugea A, Urrutia RA, Pandol SJ, Lai KKY. PMID: 32516943; PMCID: PMC7352534.
      View in: PubMed   Mentions: 9  
    8. Recent Advances in Understanding the Complexity of Alcohol-Induced Pancreatic Dysfunction and Pancreatitis Development. Biomolecules. 2020 04 27; 10(5). Rasineni K, Srinivasan MP, Balamurugan AN, Kaphalia BS, Wang S, Ding WX, Pandol SJ, Lugea A, Simon L, Molina PE, Gao P, Casey CA, Osna NA, Kharbanda KK. PMID: 32349207; PMCID: PMC7277520.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    9. Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells. Cells. 2020 01 18; 9(1). Dalva M, Lavik IK, El Jellas K, Gravdal A, Lugea A, Pandol SJ, Njølstad PR, Waldron RT, Fjeld K, Johansson BB, Molven A. PMID: 31963687; PMCID: PMC7017060.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    10. Trypsin activity governs increased susceptibility to pancreatitis in mice expressing human PRSS1R122H. J Clin Invest. 2020 01 02; 130(1):189-202. Gui F, Zhang Y, Wan J, Zhan X, Yao Y, Li Y, Haddock AN, Shi J, Guo J, Chen J, Zhu X, Edenfield BH, Zhuang L, Hu C, Wang Y, Mukhopadhyay D, Radisky ES, Zhang L, Lugea A, Pandol SJ, Bi Y, Ji B. PMID: 31550238; PMCID: PMC6934224.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    11. Yes-Associated Protein 1 Plays Major Roles in Pancreatic Stellate Cell Activation and Fibroinflammatory Responses. Front Physiol. 2019; 10:1467. Hu C, Yang J, Su HY, Waldron RT, Zhi M, Li L, Xia Q, Pandol SJ, Lugea A. PMID: 31849712; PMCID: PMC6901825.
      View in: PubMed   Mentions: 10  
    12. Brake adjustment: Ca2+ entry pathway provides a novel target for acute pancreatitis therapy. Ann Transl Med. 2019 Dec; 7(Suppl 8):S284. Waldron RT, Lugea A, Pandol SJ. PMID: 32016003; PMCID: PMC6976478.
      View in: PubMed   Mentions: 3  
    13. Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis. Biochim Biophys Acta Mol Basis Dis. 2019 11 01; 1865(11):165530. Piplani H, Marek-Iannucci S, Sin J, Hou J, Takahashi T, Sharma A, de Freitas Germano J, Waldron RT, Saadaeijahromi H, Song Y, Gulla A, Wu B, Lugea A, Andres AM, Gaisano HY, Gottlieb RA, Pandol SJ. PMID: 31398467.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    14. New-Onset Diabetes Mellitus After Chronic Pancreatitis Diagnosis: A Systematic Review and Meta-analysis. Pancreas. 2019 08; 48(7):868-875. Zhu X, Liu D, Wei Q, Lin H, Zhi M, Chen Y, Qi L, Waldron RT, Lugea A, Pandol SJ, Li L. PMID: 31268977.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    15. Incidence of New Onset Diabetes Mellitus Secondary to Acute Pancreatitis: A Systematic Review and Meta-Analysis. Front Physiol. 2019; 10:637. Zhi M, Zhu X, Lugea A, Waldron RT, Pandol SJ, Li L. PMID: 31231233; PMCID: PMC6558372.
      View in: PubMed   Mentions: 30  
    16. The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis. J Physiol. 2019 06; 597(12):3085-3105. Waldron RT, Chen Y, Pham H, Go A, Su HY, Hu C, Wen L, Husain SZ, Sugar CA, Roos J, Ramos S, Lugea A, Dunn M, Stauderman K, Pandol SJ. PMID: 31050811; PMCID: PMC6582954.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    17. Recent Insights Into the Pathogenic Mechanism of Pancreatitis: Role of Acinar Cell Organelle Disorders. Pancreas. 2019 04; 48(4):459-470. Gukovskaya AS, Gorelick FS, Groblewski GE, Mareninova OA, Lugea A, Antonucci L, Waldron RT, Habtezion A, Karin M, Pandol SJ, Gukovsky I. PMID: 30973461; PMCID: PMC6461375.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    18. Proteomic Identification of Novel Plasma Biomarkers and Pathobiologic Pathways in Alcoholic Acute Pancreatitis. Front Physiol. 2018; 9:1215. Waldron RT, Lugea A, Gulla A, Pandol SJ. PMID: 30214418; PMCID: PMC6125332.
      View in: PubMed   Mentions: 9  
    19. Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model. Cell Mol Gastroenterol Hepatol. 2018; 5(4):479-497. Waldron RT, Su HY, Piplani H, Capri J, Cohn W, Whitelegge JP, Faull KF, Sakkiah S, Abrol R, Yang W, Zhou B, Freeman MR, Pandol SJ, Lugea A. PMID: 29930975; PMCID: PMC6009017.
      View in: PubMed   Mentions: 13     Fields:    
    20. Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models. Gastroenterology. 2018 Feb; 154(3):689-703. Biczo G, Vegh ET, Shalbueva N, Mareninova OA, Elperin J, Lotshaw E, Gretler S, Lugea A, Malla SR, Dawson D, Ruchala P, Whitelegge J, French SW, Wen L, Husain SZ, Gorelick FS, Hegyi P, Rakonczay Z, Gukovsky I, Gukovskaya AS. PMID: 29074451; PMCID: PMC6369139.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    21. The Differential Role of Human Cationic Trypsinogen (PRSS1) p.R122H Mutation in Hereditary and Nonhereditary Chronic Pancreatitis: A Systematic Review and Meta-Analysis. Gastroenterol Res Pract. 2017; 2017:9505460. Hu C, Wen L, Deng L, Zhang C, Lugea A, Su HY, Waldron RT, Pandol SJ, Xia Q. PMID: 29118810; PMCID: PMC5651130.
      View in: PubMed   Mentions: 2  
    22. Human Pancreatic Acinar Cells: Proteomic Characterization, Physiologic Responses, and Organellar Disorders in ex Vivo Pancreatitis. Am J Pathol. 2017 Dec; 187(12):2726-2743. Lugea A, Waldron RT, Mareninova OA, Shalbueva N, Deng N, Su HY, Thomas DD, Jones EK, Messenger SW, Yang J, Hu C, Gukovsky I, Liu Z, Groblewski GE, Gukovskaya AS, Gorelick FS, Pandol SJ. PMID: 28935577; PMCID: PMC5718097.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    23. Diabetes Mellitus and Obesity as Risk Factors for Pancreatic Cancer. J Acad Nutr Diet. 2018 04; 118(4):555-567. Eibl G, Cruz-Monserrate Z, Korc M, Petrov MS, Goodarzi MO, Fisher WE, Habtezion A, Lugea A, Pandol SJ, Hart PA, Andersen DK, Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. PMID: 28919082; PMCID: PMC5845842.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    24. Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice. PLoS One. 2017; 12(9):e0184455. Chang HH, Moro A, Takakura K, Su HY, Mo A, Nakanishi M, Waldron RT, French SW, Dawson DW, Hines OJ, Li G, Go VLW, Sinnett-Smith J, Pandol SJ, Lugea A, Gukovskaya AS, Duff MO, Rosenberg DW, Rozengurt E, Eibl G. PMID: 28886117; PMCID: PMC5590955.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    25. The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells. Gastroenterology. 2017 12; 153(6):1674-1686. Lugea A, Gerloff A, Su HY, Xu Z, Go A, Hu C, French SW, Wilson JS, Apte MV, Waldron RT, Pandol SJ. PMID: 28847752; PMCID: PMC5705421.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    26. Exosome-Mediated Intercellular Communication Between Stellate Cells and Cancer Cells in Pancreatic Ductal Adenocarcinoma. Pancreas. 2017 01; 46(1):1-4. Lugea A, Waldron RT. PMID: 27977625; PMCID: PMC5171232.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    27. Uniting Epidemiology and Experimental Disease Models for Alcohol-Related Pancreatic Disease. Alcohol Res. 2017; 38(2):173-182. Setiawan VW, Monroe K, Lugea A, Yadav D, Pandol S. PMID: 28988572; PMCID: PMC5513684.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    28. Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models. Front Physiol. 2016; 7:498. Su D, Nie Y, Zhu A, Chen Z, Wu P, Zhang L, Luo M, Sun Q, Cai L, Lai Y, Xiao Z, Duan Z, Zheng S, Wu G, Hu R, Tsukamoto H, Lugea A, Liu Z, Pandol SJ, Han YP. PMID: 27895587; PMCID: PMC5108805.
      View in: PubMed   Mentions: 83  
    29. Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G675-G687. Yang J, Waldron RT, Su HY, Moro A, Chang HH, Eibl G, Ferreri K, Kandeel FR, Lugea A, Li L, Pandol SJ. PMID: 27609771; PMCID: PMC5142202.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    30. The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells. PLoS One. 2016; 11(2):e0148999. Su HY, Waldron RT, Gong R, Ramanujan VK, Pandol SJ, Lugea A. PMID: 26849807; PMCID: PMC4743835.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    31. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, et al. PMID: 26799652; PMCID: PMC4835977.
      View in: PubMed   Mentions: 2775     Fields:    Translation:HumansAnimals
    32. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology. 2015 Jul; 15(4 Suppl):S1-5. Lugea A, Waldron RT, Pandol SJ. PMID: 25736240; PMCID: PMC4515411.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    33. Diabetes, pancreatic cancer, and metformin therapy. Front Physiol. 2014; 5:426. Gong J, Robbins LA, Lugea A, Waldron RT, Jeon CY, Pandol SJ. PMID: 25426078; PMCID: PMC4224068.
      View in: PubMed   Mentions: 35  
    34. Genetic inhibition of protein kinase Cε attenuates necrosis in experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2014 Sep 01; 307(5):G550-63. Liu Y, Yuan J, Tan T, Jia W, Lugea A, Mareninova O, Waldron RT, Pandol SJ. PMID: 25035113; PMCID: PMC4154116.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    35. Ellagic acid and embelin affect key cellular components of pancreatic adenocarcinoma, cancer, and stellate cells. Nutr Cancer. 2013; 65(8):1232-44. Edderkaoui M, Lugea A, Hui H, Eibl G, Lu QY, Moro A, Lu X, Li G, Go VL, Pandol SJ. PMID: 24127740; PMCID: PMC3909533.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    36. High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model. Cancer Prev Res (Phila). 2013 Oct; 6(10):1064-73. Dawson DW, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol SJ, Lugea A, Gukovskaya AS, Li G, Hines OJ, Rozengurt E, Eibl G. PMID: 23943783; PMCID: PMC3835151.
      View in: PubMed   Mentions: 74     Fields:    Translation:Animals
    37. A starring role for stellate cells in the pancreatic cancer microenvironment. Gastroenterology. 2013 Jun; 144(6):1210-9. Apte MV, Wilson JS, Lugea A, Pandol SJ. PMID: 23622130; PMCID: PMC3729446.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansAnimalsCells
    38. Determination of Rottlerin, a Natural Protein Kinases C Inhibitor, in Pancreatic Cancer Cells and Mouse Xenografts by RP-HPLC Method. J Chromatogr Sep Tech. 2013 Jan 01; 4(1). Lu QY, Zhang L, Lugea A, Moro A, Edderkaoui M, Eibl G, Pandol SJ, Go VL. PMID: 24482742; PMCID: PMC3904376.
      View in: PubMed   Mentions: 8  
    39. Epidemiology, risk factors, and the promotion of pancreatic cancer: role of the stellate cell. J Gastroenterol Hepatol. 2012 Mar; 27 Suppl 2:127-34. Pandol S, Gukovskaya A, Edderkaoui M, Edderkoui M, Dawson D, Eibl G, Lugea A. PMID: 22320930; PMCID: PMC3736749.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    40. Pigment epithelium-derived factor regulates early pancreatic fibrotic responses and suppresses the profibrotic cytokine thrombospondin-1. Am J Pathol. 2011 Dec; 179(6):2990-9. Schmitz JC, Protiva P, Gattu AK, Utsumi T, Iwakiri Y, Neto AG, Quinn M, Cornwell ML, Fitchev P, Lugea A, Crawford SE, Chung C. PMID: 21964188; PMCID: PMC3260804.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    41. Drinking and driving pancreatitis: links between endoplasmic reticulum stress and autophagy. Autophagy. 2011 Jul; 7(7):783-5. Lugea A, Waldron RT, French SW, Pandol SJ. PMID: 21460613; PMCID: PMC3359467.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    42. Alcohol abuse, endoplasmic reticulum stress and pancreatitis. Dig Dis. 2010; 28(6):776-82. Pandol SJ, Gorelick FS, Gerloff A, Lugea A. PMID: 21525762; PMCID: PMC3211518.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    43. Environmental and genetic stressors and the unfolded protein response in exocrine pancreatic function - a hypothesis. Front Physiol. 2011; 2:8. Pandol SJ, Gorelick FS, Lugea A. PMID: 21483727; PMCID: PMC3070477.
      View in: PubMed   Mentions: 24  
    44. Investigating the pathobiology of alcoholic pancreatitis. Alcohol Clin Exp Res. 2011 May; 35(5):830-7. Pandol SJ, Lugea A, Mareninova OA, Smoot D, Gorelick FS, Gukovskaya AS, Gukovsky I. PMID: 21284675; PMCID: PMC3083481.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    45. Synergistic steatohepatitis by moderate obesity and alcohol in mice despite increased adiponectin and p-AMPK. J Hepatol. 2011 Sep; 55(3):673-682. Xu J, Lai KKY, Verlinsky A, Lugea A, French SW, Cooper MP, Ji C, Tsukamoto H. PMID: 21256905; PMCID: PMC3094601.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    46. Adaptive unfolded protein response attenuates alcohol-induced pancreatic damage. Gastroenterology. 2011 Mar; 140(3):987-97. Lugea A, Tischler D, Nguyen J, Gong J, Gukovsky I, French SW, Gorelick FS, Pandol SJ. PMID: 21111739; PMCID: PMC3057335.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    47. Cholinergic mediation of alcohol-induced experimental pancreatitis. Alcohol Clin Exp Res. 2010 Oct; 34(10):1768-81. Lugea A, Gong J, Nguyen J, Nieto J, French SW, Pandol SJ. PMID: 20626730; PMCID: PMC2950903.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    48. Protein kinase C delta-mediated processes in cholecystokinin-8-stimulated pancreatic acini. Pancreas. 2009 Nov; 38(8):930-5. Thrower EC, Wang J, Cheriyan S, Lugea A, Kolodecik TR, Yuan J, Reeve JR, Gorelick FS, Pandol SJ. PMID: 19752773; PMCID: PMC2767410.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    49. Desmoplasia of pancreatic ductal adenocarcinoma. Clin Gastroenterol Hepatol. 2009 Nov; 7(11 Suppl):S44-7. Pandol S, Edderkaoui M, Gukovsky I, Lugea A, Gukovskaya A. PMID: 19896098; PMCID: PMC4573641.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    50. Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2008 Dec; 295(6):G1190-201. Yuan J, Lugea A, Zheng L, Gukovsky I, Edderkaoui M, Rozengurt E, Pandol SJ. PMID: 18845574; PMCID: PMC2604803.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    51. A rat model reproducing key pathological responses of alcoholic chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2008 Jan; 294(1):G68-79. Gukovsky I, Lugea A, Shahsahebi M, Cheng JH, Hong PP, Jung YJ, Deng QG, French BA, Lungo W, French SW, Tsukamoto H, Pandol SJ. PMID: 17884979.
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    52. Ethanol augments PDGF-induced NADPH oxidase activity and proliferation in rat pancreatic stellate cells. Pancreatology. 2007; 7(4):332-40. Hu R, Wang YL, Edderkaoui M, Lugea A, Apte MV, Pandol SJ. PMID: 17627098; PMCID: PMC2826430.
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    53. Alcohol redirects CCK-mediated apical exocytosis to the acinar basolateral membrane in alcoholic pancreatitis. Traffic. 2007 May; 8(5):605-17. Lam PP, Cosen Binker LI, Lugea A, Pandol SJ, Gaisano HY. PMID: 17451559.
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    54. The pancreatic stellate cell: a star on the rise in pancreatic diseases. J Clin Invest. 2007 Jan; 117(1):50-9. Omary MB, Lugea A, Lowe AW, Pandol SJ. PMID: 17200706; PMCID: PMC1716214.
      View in: PubMed   Mentions: 316     Fields:    Translation:HumansCells
    55. Substance P mediates cerulein-induced pancreatic microcirculatory dysfunction in mice. Pancreas. 2007 Jan; 34(1):138-43. Ito Y, Lugea A, Pandol SJ, McCuskey RS. PMID: 17198196.
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    56. Polyethylene glycol enhances colonic barrier function and ameliorates experimental colitis in rats. Int J Colorectal Dis. 2007 Jun; 22(6):571-80. Videla S, Lugea A, Vilaseca J, Guarner F, Treserra F, Salas A, Crespo E, Medina C, Malagelada JR. PMID: 17061105.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    57. Cell death in pancreatitis: effects of alcohol. J Gastroenterol Hepatol. 2006 Oct; 21 Suppl 3:S10-3. Gukovskaya AS, Mareninova OA, Odinokova IV, Sung KF, Lugea A, Fischer L, Wang YL, Gukovsky I, Pandol SJ. PMID: 16958657.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    58. Pancreas recovery following cerulein-induced pancreatitis is impaired in plasminogen-deficient mice. Gastroenterology. 2006 Sep; 131(3):885-99. Lugea A, Nan L, French SW, Bezerra JA, Gukovskaya AS, Pandol SJ. PMID: 16952557; PMCID: PMC1636452.
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    59. Long-term ethanol consumption alters pancreatic gene expression in rats: a possible connection to pancreatic injury. Pancreas. 2006 Jul; 33(1):68-76. Kubisch CH, Gukovsky I, Lugea A, Pandol SJ, Kuick R, Misek DE, Hanash SM, Logsdon CD. PMID: 16804415.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    60. Ethanol feeding alters death signaling in the pancreas. Pancreas. 2006 May; 32(4):351-9. Wang YL, Hu R, Lugea A, Gukovsky I, Smoot D, Gukovskaya AS, Pandol SJ. PMID: 16670617.
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    61. Cell death in pancreatitis: caspases protect from necrotizing pancreatitis. J Biol Chem. 2006 Feb 10; 281(6):3370-81. Mareninova OA, Sung KF, Hong P, Lugea A, Pandol SJ, Gukovsky I, Gukovskaya AS. PMID: 16339139.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    62. Phosphatidylinositol 3-kinase regulates Ca2+ signaling in pancreatic acinar cells through inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase. Am J Physiol Gastrointest Liver Physiol. 2004 Dec; 287(6):G1200-12. Fischer L, Gukovskaya AS, Young SH, Gukovsky I, Lugea A, Buechler P, Penninger JM, Friess H, Pandol SJ. PMID: 15271649.
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    63. Phosphatidylinositide 3-kinase gamma regulates key pathologic responses to cholecystokinin in pancreatic acinar cells. Gastroenterology. 2004 Feb; 126(2):554-66. Gukovsky I, Cheng JH, Nam KJ, Lee OT, Lugea A, Fischer L, Penninger JM, Pandol SJ, Gukovskaya AS. PMID: 14762792.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    64. Nonoxidative ethanol metabolites alter extracellular matrix protein content in rat pancreas. Gastroenterology. 2003 Dec; 125(6):1845-59. Lugea A, Gukovsky I, Gukovskaya AS, Pandol SJ. PMID: 14724836.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    65. Animal and in vitro models of alcoholic pancreatitis: role of cholecystokinin. Pancreas. 2003 Nov; 27(4):297-300. Pandol SJ, Gukovsky I, Satoh A, Lugea A, Gukovskaya AS. PMID: 14576490.
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    66. Emerging concepts for the mechanism of alcoholic pancreatitis from experimental models. J Gastroenterol. 2003; 38(7):623-8. Pandol SJ, Gukovsky I, Satoh A, Lugea A, Gukovskaya AS. PMID: 12898353.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    67. Epidermal growth factor increases surface hydrophobicity and resistance to acid in the rat duodenum. Am J Physiol Gastrointest Liver Physiol. 2001 Apr; 280(4):G774-9. Lugea A, Mourelle M, Domingo A, Salas A, Guarner F, Malagelada JR. PMID: 11254505.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    68. Surface hydrophobicity of the rat colonic mucosa is a defensive barrier against macromolecules and toxins. Gut. 2000 Apr; 46(4):515-21. Lugea A, Salas A, Casalot J, Guarner F, Malagelada JR. PMID: 10716681; PMCID: PMC1727902.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    69. Deranged hydrophobic barrier of the rat gastroduodenal mucosa after parenteral nonsteroidal anti-inflammatory drugs. Gastroenterology. 1997 Jun; 112(6):1931-9. Lugea A, Antolín M, Mourelle M, Guarner F, Malagelada JR. PMID: 9178685.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    70. Effect of zinc on D-galactose and L-phenylalanine uptake in rat intestine in vitro. Rev Esp Fisiol. 1995 Sep; 51(3):139-46. Lugea A, Barber A, Ponz F. PMID: 8606991.
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    71. Phosphatidylcholines as mediators of adaptive cytoprotection of the rat duodenum. Gastroenterology. 1994 Sep; 107(3):720-7. Lugea A, Mourelle M, Guarner F, Domingo A, Salas A, Malagelada JR. PMID: 8076757.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    72. Inhibition of D-galactose and L-phenylalanine transport by HgCl2 in rat intestine in vitro. Rev Esp Fisiol. 1994 Sep; 50(3):167-73. Lugea A, Barber A, Ponz F. PMID: 7886274.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    73. Influence of dietary fat on duodenal resistance to acid. Gut. 1993 Oct; 34(10):1303-9. Lugea A, Salas A, Guarner F, Malagelada JR. PMID: 8244092; PMCID: PMC1374531.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    74. Adaptive cytoprotection of the rat duodenum is not dependent on nitric oxide-induced changes in blood flow. Am J Physiol. 1993 May; 264(5 Pt 1):G994-1000. Lugea A, Salas A, Guarner F, Malagelada JR. PMID: 7684570.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    75. Duodenal mucosal resistance to intraluminal acid in the rat: role of adaptive cytoprotection. Gastroenterology. 1992 Apr; 102(4 Pt 1):1129-35. Lugea A, Salas A, Guarner F, Azpiroz F, Malagelada JR. PMID: 1551521.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    76. Antiulcerogenic and antiinflammatory actions of fatty acids on the gastrointestinal tract. Prostaglandins Leukot Essent Fatty Acids. 1991 Jul; 43(3):135-40. Lugea A, Videla S, Vilaseca J, Guarner F. PMID: 1871179.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    77. Inhibition of sugar and amino acid transport across rat jejunum by cadmium, copper and mercury. Rev Esp Fisiol. 1989; 45 Suppl:207-14. Rodríguez-Yoldi MJ, Lugea A, Barber A, Lluch M, Ponz F. PMID: 2641822.
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    78. Inhibition by cadmium of D-galactose and L-phenylalanine transport by rat intestine in vitro. Rev Esp Fisiol. 1988 Jun; 44(2):121-6. Lugea A, Barber A, Ponz F. PMID: 3143131.
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