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Mouad Edderkaoui

Title(s)Associate Adjunct Professor, Medicine
SchoolMedicine
Address760 Westwood Plaza 32-144
Los Angeles CA 90024
Phone(310) 248-8024
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dual targeting of GSK3B and HDACs reduces tumor growth and improves survival in an ovarian cancer mouse model. Gynecol Oncol. 2020 Jul 19. Taylan E, Zayou F, Murali R, Karlan BY, Pandol SJ, Edderkaoui M, Orsulic S. PMID: 32698955.
      View in: PubMed   Mentions:    Fields:    
    2. Animal Models: Challenges and Opportunities to Determine Optimal Experimental Models of Pancreatitis and Pancreatic Cancer. Pancreas. 2019 07; 48(6):759-779. Saloman JL, Albers KM, Cruz-Monserrate Z, Davis BM, Edderkaoui M, Eibl G, Epouhe AY, Gedeon JY, Gorelick FS, Grippo PJ, Groblewski GE, Husain SZ, Lai KKY, Pandol SJ, Uc A, Wen L, Whitcomb DC. PMID: 31206467.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    3. MSP-RON Signaling Is Activated in the Transition From Pancreatic Intraepithelial Neoplasia (PanIN) to Pancreatic Ductal Adenocarcinoma (PDAC). Front Physiol. 2019; 10:147. Li C, Morvaridi S, Lam G, Chheda C, Kamata Y, Katsumata M, Edderkaoui M, Yuan X, Nissen N, Pandol SJ, Wang Q. PMID: 30863319.
      View in: PubMed   Mentions:
    4. An Inhibitor of GSK3B and HDACs Kills Pancreatic Cancer Cells and Slows Pancreatic Tumor Growth and Metastasis in Mice. Gastroenterology. 2018 12; 155(6):1985-1998.e5. Edderkaoui M, Chheda C, Soufi B, Zayou F, Hu RW, Ramanujan VK, Pan X, Boros LG, Tajbakhsh J, Madhav A, Bhowmick NA, Wang Q, Lewis M, Tuli R, Habtezion A, Murali R, Pandol SJ. PMID: 30144430.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    5. Tobacco and alcohol as risk factors for pancreatic cancer. Best Pract Res Clin Gastroenterol. 2017 Oct; 31(5):529-536. Korc M, Jeon CY, Edderkaoui M, Pandol SJ, Petrov MS. PMID: 29195672.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    6. The Potential for Circulating Tumor Cells in Pancreatic Cancer Management. Front Physiol. 2017; 8:381. Pimienta M, Edderkaoui M, Wang R, Pandol S. PMID: 28626429.
      View in: PubMed   Mentions:
    7. Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration. Am J Pathol. 2017 Jan; 187(1):146-155. Birtolo C, Pham H, Morvaridi S, Chheda C, Go VL, Ptasznik A, Edderkaoui M, Weisman MH, Noss E, Brenner MB, Larson B, Guindi M, Wang Q, Pandol SJ. PMID: 27855278.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    8. Aryl Hydrocarbon Receptor Ligands in Cigarette Smoke Induce Production of Interleukin-22 to Promote Pancreatic Fibrosis in Models of Chronic Pancreatitis. Gastroenterology. 2016 12; 151(6):1206-1217. Xue J, Zhao Q, Sharma V, Nguyen LP, Lee YN, Pham KL, Edderkaoui M, Pandol SJ, Park W, Habtezion A. PMID: 27769811.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    9. HDAC3 mediates smoking-induced pancreatic cancer. Oncotarget. 2016 Feb 16; 7(7):7747-60. Edderkaoui M, Xu S, Chheda C, Morvaridi S, Hu RW, Grippo PJ, Mascariñas E, Principe DR, Knudsen B, Xue J, Habtezion A, Uyeminami D, Pinkerton KE, Pandol SJ. PMID: 26745602.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    10. Macrophages and pancreatic ductal adenocarcinoma. Cancer Lett. 2016 10 10; 381(1):211-6. Habtezion A, Edderkaoui M, Pandol SJ. PMID: 26708507.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    11. Characterization of Mouse Models of Early Pancreatic Lesions Induced by Alcohol and Chronic Pancreatitis. Pancreas. 2015 Aug; 44(6):882-7. Xu S, Chheda C, Ouhaddi Y, Benhaddou H, Bourhim M, Grippo PJ, Principe DR, Mascariñas E, DeCant B, Tsukamoto H, Pandol SJ, Edderkaoui M. PMID: 26166469.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    12. What are the macrophages and stellate cells doing in pancreatic adenocarcinoma? Front Physiol. 2015; 6:125. Pandol SJ, Edderkaoui M. PMID: 26029109.
      View in: PubMed   Mentions:
    13. Risk factors for pancreatic cancer: underlying mechanisms and potential targets. Front Physiol. 2014; 5:490. Edderkaoui M, Eibl G. PMID: 25540626.
      View in: PubMed   Mentions:
    14. NADPH oxidase activation in pancreatic cancer cells is mediated through Akt-dependent up-regulation of p22phox. J Biol Chem. 2013 Dec 20; 288(51):36259. Edderkaoui M, Nitsche C, Zheng L, Pandol SJ, Gukovsky I, Gukovskaya AS. PMID: 24363267.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    15. Smoking and Pancreatic Disease. J Cancer Ther. 2013 Nov 01; 4(10A):34-40. Edderkaoui M, Thrower E. PMID: 24660091.
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    16. Ellagic acid and embelin affect key cellular components of pancreatic adenocarcinoma, cancer, and stellate cells. Nutr Cancer. 2013; 65(8):1232-44. Edderkaoui M, Lugea A, Hui H, Eibl G, Lu QY, Moro A, Lu X, Li G, Go VL, Pandol SJ. PMID: 24127740.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    17. Akt kinase mediates the prosurvival effect of smoking compounds in pancreatic ductal cells. Pancreas. 2013 May; 42(4):655-62. Park CH, Lee IS, Grippo P, Pandol SJ, Gukovskaya AS, Edderkaoui M. PMID: 23271397.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    18. Determination of Rottlerin, a Natural Protein Kinases C Inhibitor, in Pancreatic Cancer Cells and Mouse Xenografts by RP-HPLC Method. J Chromatogr Sep Tech. 2013 Jan 01; 4(1). Lu QY, Zhang L, Lugea A, Moro A, Edderkaoui M, Eibl G, Pandol SJ, Go VL. PMID: 24482742.
      View in: PubMed   Mentions:
    19. The burning question: why is smoking a risk factor for pancreatic cancer? Pancreatology. 2012 Jul-Aug; 12(4):344-9. Pandol SJ, Apte MV, Wilson JS, Gukovskaya AS, Edderkaoui M. PMID: 22898636.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    20. Molecular basis for the interplay of apoptosis and proliferation mediated by Bcl-xL:Bim interactions in pancreatic cancer cells. Biochem Biophys Res Commun. 2012 Jun 15; 422(4):596-601. Abrol R, Edderkaoui M, Goddard WA, Pandol SJ. PMID: 22609401.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Epidemiology, risk factors, and the promotion of pancreatic cancer: role of the stellate cell. J Gastroenterol Hepatol. 2012 Mar; 27 Suppl 2:127-34. Pandol S, Gukovskaya A, Edderkaoui M, Edderkoui M, Dawson D, Eibl G, Lugea A. PMID: 22320930.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    22. The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation. Gastroenterology. 2012 Feb; 142(2):377-87.e1-5. Nitsche C, Edderkaoui M, Moore RM, Eibl G, Kasahara N, Treger J, Grippo PJ, Mayerle J, Lerch MM, Gukovskaya AS. PMID: 22044669.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    23. NADPH oxidase activation in pancreatic cancer cells is mediated through Akt-dependent up-regulation of p22phox. J Biol Chem. 2011 03 11; 286(10):7779-87. Edderkaoui M, Nitsche C, Zheng L, Pandol SJ, Gukovsky I, Gukovskaya AS. PMID: 21118808.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    24. Desmoplasia of pancreatic ductal adenocarcinoma. Clin Gastroenterol Hepatol. 2009 Nov; 7(11 Suppl):S44-7. Pandol S, Edderkaoui M, Gukovsky I, Lugea A, Gukovskaya A. PMID: 19896098.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    25. Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family. Am J Physiol Gastrointest Liver Physiol. 2010 Jan; 298(1):G63-73. Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA, Yokosuka O, Pandol SJ, Gukovskaya AS. PMID: 19762431.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    26. Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2008 Dec; 295(6):G1190-201. Yuan J, Lugea A, Zheng L, Gukovsky I, Edderkaoui M, Rozengurt E, Pandol SJ. PMID: 18845574.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    27. Ellagic acid induces apoptosis through inhibition of nuclear factor kappa B in pancreatic cancer cells. World J Gastroenterol. 2008 Jun 21; 14(23):3672-80. Edderkaoui M, Odinokova I, Ohno I, Gukovsky I, Go VL, Pandol SJ, Gukovskaya AS. PMID: 18595134.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    28. NADPH oxidase promotes pancreatic cancer cell survival via inhibiting JAK2 dephosphorylation by tyrosine phosphatases. Gastroenterology. 2007 Nov; 133(5):1637-48. Lee JK, Edderkaoui M, Truong P, Ohno I, Jang KT, Berti A, Pandol SJ, Gukovskaya AS. PMID: 17983808.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    29. Insulin-like growth factor-I receptor mediates the prosurvival effect of fibronectin. J Biol Chem. 2007 Sep 14; 282(37):26646-55. Edderkaoui M, Hong P, Lee JK, Pandol SJ, Gukovskaya AS. PMID: 17627944.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    30. Ethanol augments PDGF-induced NADPH oxidase activity and proliferation in rat pancreatic stellate cells. Pancreatology. 2007; 7(4):332-40. Hu R, Wang YL, Edderkaoui M, Lugea A, Apte MV, Pandol SJ. PMID: 17627098.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    31. Tumor necrosis factor-alpha mediates pancreatitis responses in acinar cells via protein kinase C and proline-rich tyrosine kinase 2. Gastroenterology. 2005 Aug; 129(2):639-51. Satoh A, Gukovskaya AS, Edderkaoui M, Daghighian MS, Reeve JR, Shimosegawa T, Pandol SJ. PMID: 16083718.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    32. Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase. Am J Physiol Gastrointest Liver Physiol. 2005 Dec; 289(6):G1137-47. Edderkaoui M, Hong P, Vaquero EC, Lee JK, Fischer L, Friess H, Buchler MW, Lerch MM, Pandol SJ, Gukovskaya AS. PMID: 16037546.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    33. Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells. J Biol Chem. 2004 Aug 13; 279(33):34643-54. Vaquero EC, Edderkaoui M, Pandol SJ, Gukovsky I, Gukovskaya AS. PMID: 15155719.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    34. Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways. Gastroenterology. 2003 Oct; 125(4):1188-202. Vaquero EC, Edderkaoui M, Nam KJ, Gukovsky I, Pandol SJ, Gukovskaya AS. PMID: 14517801.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
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