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Stephen J Pandol

Title(s)Professor-in-Residence, Medicine
SchoolMedicine
Phone(310) 423-4139
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    Collapse Research 
    Collapse Research Activities and Funding
    Evaluation of SBP-101 for the Treatment of Acute Pancreatitis
    NIH/NIDDK R41DK111337Sep 21, 2016 - Aug 31, 2017
    Role: Co-Principal Investigator
    Targeting protein kinase D in alcoholic pancreatitis
    NIH/NIAAA R01AA024464Sep 1, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Pathophysiology, Epidemiology, and Prevention of Pancreatogenic Diabetes
    NIH/NIDDK U01DK108314Sep 28, 2015 - Aug 31, 2020
    Role: Principal Investigator
    Smoking, Alcohol Abuse and the Pancreas
    VA I01BX001484Jul 1, 2012 - Jun 30, 2016
    Role: Principal Investigator
    Alcohol and the Exocrine Pancreas ER Stress Responses
    NIH/NIAAA R21AA016010Mar 1, 2006 - Feb 29, 2008
    Role: Principal Investigator
    THE INFLAMMATORY RESPONSE OF THE PANCREATIC ACINAR CELL
    NIH/NIDDK R01DK059508May 1, 2002 - Apr 30, 2008
    Role: Principal Investigator
    MECHANISM OF ETHANOL INDUCED PANCREATITIS
    NIH/NIDDK R01DK051476Sep 30, 1995 - Aug 31, 1998
    Role: Principal Investigator
    FUNCTION AND SUBCELLULAR NATURE OF CALCIUM SIGNALING
    NIH/NIDDK R01DK033010Dec 1, 1983 - Nov 30, 1998
    Role: Principal Investigator
    PANCREATIC SECRETION AND PHOSPHATIDYLINOSITOL METABOLISM
    NIH/NIADDK R01AM033010Dec 1, 1983 - Nov 30, 1986
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Jeon CY, Chen Q, Yu W, Dong EY, Chung J, Pandol SJ, Yadav D, Conwell DL, Wu BU. Identification of Individuals at Increased Risk for Pancreatic Cancer in a Community-Based Cohort of Patients With Suspected Chronic Pancreatitis. Clin Transl Gastroenterol. 2020 Apr; 11(4):e00147. PMID: 32352677.
      View in: PubMed
    2. Taylor DJR, Hamid SM, Andres AM, Saadaeijahromi H, Piplani H, Germano JF, Song Y, Sawaged S, Feuer R, Pandol SJ, Sin J. Antiviral Effects of Menthol on Coxsackievirus B. Viruses. 2020 Mar 28; 12(4). PMID: 32231022.
      View in: PubMed
    3. Pereira SP, Oldfield L, Ney A, Hart PA, Keane MG, Pandol SJ, Li D, Greenhalf W, Jeon CY, Koay EJ, Almario CV, Halloran C, Lennon AM, Costello E. Early detection of pancreatic cancer. Lancet Gastroenterol Hepatol. 2020 Mar 02. PMID: 32135127.
      View in: PubMed
    4. Wang N, Gaddam S, Wang L, Xie Y, Fan Z, Yang W, Tuli R, Lo S, Hendifar A, Pandol S, Christodoulou AG, Li D. Six-dimensional quantitative DCE MR Multitasking of the entire abdomen: Method and application to pancreatic ductal adenocarcinoma. Magn Reson Med. 2020 Aug; 84(2):928-948. PMID: 31961967.
      View in: PubMed
    5. Wang R, Lewis MS, Lyu J, Zhau HE, Pandol SJ, Chung LWK. Cancer-stromal cell fusion as revealed by fluorescence protein tracking. Prostate. 2020 Feb; 80(3):274-283. PMID: 31846114.
      View in: PubMed
    6. Weissman S, Amrutiya V, Saleem S, Mehta TI, Aziz M, Lo A, Elias S, Sotiriadis J, Takakura K, Pandol SJ, Tabibian JH. Herbal supplement-induced acute pancreatitis: An unfamiliar culprit. Pancreatology. 2019 Dec 13. PMID: 31864812.
      View in: PubMed
    7. Huang BZ, Pandol SJ, Jeon CY, Chari ST, Sugar CA, Chao CR, Zhang ZF, Wu BU, Wendy Setiawan V. New-Onset Diabetes, Longitudinal Trends in Metabolic Markers, and Risk of Pancreatic Cancer in a Heterogeneous Population. Clin Gastroenterol Hepatol. 2019 Dec 04. PMID: 31809917.
      View in: PubMed
    8. Waldron RT, Lugea A, Pandol SJ. Brake adjustment: Ca2+ entry pathway provides a novel target for acute pancreatitis therapy. Ann Transl Med. 2019 Dec; 7(Suppl 8):S284. PMID: 32016003.
      View in: PubMed
    9. Piplani H, Marek-Iannucci S, Sin J, Hou J, Takahashi T, Sharma A, de Freitas Germano J, Waldron RT, Saadaeijahromi H, Song Y, Gulla A, Wu B, Lugea A, Andres AM, Gaisano HY, Gottlieb RA, Pandol SJ. Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis. Biochim Biophys Acta Mol Basis Dis. 2019 Nov 01; 1865(11):165530. PMID: 31398467.
      View in: PubMed
    10. Goodarzi MO, Nagpal T, Greer P, Cui J, Chen YI, Guo X, Pankow JS, Rotter JI, Alkaade S, Amann ST, Baillie J, Banks PA, Brand RE, Conwell DL, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, LaRusch J, Lewis MD, Money ME, Muniraj T, Papachristou GI, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Wilcox CM, Pandol SJ, Park WG, Andersen DK, Bellin MD, Hart PA, Yadav D, Whitcomb DC. Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus. Clin Transl Gastroenterol. 2019 07; 10(7):e00057. PMID: 31232720.
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    11. Ohashi K, Wang Z, Yang YM, Billet S, Tu W, Pimienta M, Cassel SL, Pandol SJ, Lu SC, Sutterwala FS, Bhowmick N, Seki E. NOD-like receptor C4 Inflammasome Regulates the Growth of Colon Cancer Liver Metastasis in NAFLD. Hepatology. 2019 Nov; 70(5):1582-1599. PMID: 31044438.
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    12. Waldron RT, Chen Y, Pham H, Go A, Su HY, Hu C, Wen L, Husain SZ, Sugar CA, Roos J, Ramos S, Lugea A, Dunn M, Stauderman K, Pandol SJ. The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis. J Physiol. 2019 Jun; 597(12):3085-3105. PMID: 31050811.
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    13. Yuan J, Hasdemir B, Tan T, Chheda C, Rivier J, Pandol SJ, Bhargava A. Protective effects of urocortin 2 against caerulein-induced acute pancreatitis. PLoS One. 2019; 14(5):e0217065. PMID: 31100090.
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    14. Setiawan VW, Stram DO, Porcel J, Chari ST, Maskarinec G, Le Marchand L, Wilkens LR, Haiman CA, Pandol SJ, Monroe KR. Pancreatic Cancer Following Incident Diabetes in African Americans and Latinos: The Multiethnic Cohort. J Natl Cancer Inst. 2019 01 01; 111(1):27-33. PMID: 29917105.
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    15. Saylor J, Ma Z, Goodridge HS, Huang F, Cress AE, Pandol SJ, Shiao SL, Vidal AC, Wu L, Nickols NG, Gertych A, Knudsen BS. Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining. Front Immunol. 2018; 9:2925. PMID: 30619287.
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    16. Forsmark CE, Andersen DK, Farrar JT, Golden M, Habtezion A, Husain SZ, Li L, Mayerle J, Pandol SJ, Uc A, Zhu Z, Yadav D. Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis: Summary of the Working Group on Drug Development and Trials in Chronic Pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas. 2018 Nov/Dec; 47(10):1200-1207. PMID: 30325858.
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    17. Yadav D, Park WG, Fogel EL, Li L, Chari ST, Feng Z, Fisher WE, Forsmark CE, Jeon CY, Habtezion A, Hart PA, Hughes SJ, Othman MO, Rinaudo JAS, Pandol SJ, Tirkes T, Serrano J, Srivastava S, Van Den Eeden SK, Whitcomb DC, Topazian M, Conwell DL. PROspective Evaluation of Chronic Pancreatitis for EpidEmiologic and Translational StuDies: Rationale and Study Design for PROCEED From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1229-1238. PMID: 30325862.
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    18. Abu-El-Haija M, Gukovskaya AS, Andersen DK, Gardner TB, Hegyi P, Pandol SJ, Papachristou GI, Saluja AK, Singh VK, Uc A, Wu BU. Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis: Summary of the Working Group on Drug Development and Trials in Acute Pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas. 2018 Nov/Dec; 47(10):1185-1192. PMID: 30325856.
      View in: PubMed
    19. Lowe ME, Goodman MT, Coté GA, Glesby MJ, Haupt M, Schork NJ, Singh VK, Andersen DK, Pandol SJ, Uc A, Whitcomb DC. Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis: Summary of the Working Group on Drug Development and Trials in Recurrent Acute Pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas. 2018 Nov/Dec; 47(10):1193-1199. PMID: 30325857.
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    20. Serrano J, Andersen DK, Forsmark CE, Pandol SJ, Feng Z, Srivastava S, Rinaudo JAS. Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer: From Concept to Reality. Pancreas. 2018 Nov/Dec; 47(10):1208-1212. PMID: 30325859.
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    21. Fisher WE, Cruz-Monserrate Z, McElhany AL, Lesinski GB, Hart PA, Ghosh R, Van Buren G, Fishman DS, Rinaudo JAS, Serrano J, Srivastava S, Mace T, Topazian M, Feng Z, Yadav D, Pandol SJ, Hughes SJ, Liu RY, Lu E, Orr R, Whitcomb DC, Abouhamze AS, Steen H, Sellers ZM, Troendle DM, Uc A, Lowe ME, Conwell DL. Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1213-1221. PMID: 30325860.
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    22. Uc A, Andersen DK, Borowitz D, Glesby MJ, Mayerle J, Sutton R, Pandol SJ. Accelerating the Drug Delivery Pipeline for Acute and Chronic Pancreatitis-Knowledge Gaps and Research Opportunities: Overview Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas. 2018 Nov/Dec; 47(10):1180-1184. PMID: 30325855.
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    23. Andersen DK, Forsmark CE, Pandol SJ. The Agenda for Accelerating Pancreatic Research. Pancreas. 2018 Nov/Dec; 47(10):1177-1179. PMID: 30325854.
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    24. Maitra A, Sharma A, Brand RE, Van Den Eeden SK, Fisher WE, Hart PA, Hughes SJ, Mather KJ, Pandol SJ, Park WG, Feng Z, Serrano J, Rinaudo JAS, Srivastava S, Chari ST. A Prospective Study to Establish a New-Onset Diabetes Cohort: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1244-1248. PMID: 30325864.
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    25. Waldron RT, Lugea A, Gulla A, Pandol SJ. Proteomic Identification of Novel Plasma Biomarkers and Pathobiologic Pathways in Alcoholic Acute Pancreatitis. Front Physiol. 2018; 9:1215. PMID: 30214418.
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    26. Edderkaoui M, Chheda C, Soufi B, Zayou F, Hu RW, Ramanujan VK, Pan X, Boros LG, Tajbakhsh J, Madhav A, Bhowmick NA, Wang Q, Lewis M, Tuli R, Habtezion A, Murali R, Pandol SJ. An Inhibitor of GSK3B and HDACs Kills Pancreatic Cancer Cells and Slows Pancreatic Tumor Growth and Metastasis in Mice. Gastroenterology. 2018 12; 155(6):1985-1998.e5. PMID: 30144430.
      View in: PubMed
    27. Lew D, Wu BU, Pandol SJ, Sugar CA, Senturk D, Afghani E. Disease Course Differences in Acute Pancreatitis Based on Etiology Using the Pancreatitis Activity Scoring System. Pancreas. 2018 08; 47(7):e40-e41. PMID: 29985848.
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    28. Manegold P, Lai KKY, Wu Y, Teo JL, Lenz HJ, Genyk YS, Pandol SJ, Wu K, Lin DP, Chen Y, Nguyen C, Zhao Y, Kahn M. Differentiation Therapy Targeting the ß-Catenin/CBP Interaction in Pancreatic Cancer. Cancers (Basel). 2018 Mar 29; 10(4). PMID: 29596326.
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    29. Buxbaum J, Quezada M, Chong B, Gupta N, Yu CY, Lane C, Da B, Leung K, Shulman I, Pandol S, Wu B. The Pancreatitis Activity Scoring System predicts clinical outcomes in acute pancreatitis: findings from a prospective cohort study. Am J Gastroenterol. 2018 05; 113(5):755-764. PMID: 29545634.
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    30. Waldron RT, Su HY, Piplani H, Capri J, Cohn W, Whitelegge JP, Faull KF, Sakkiah S, Abrol R, Yang W, Zhou B, Freeman MR, Pandol SJ, Lugea A. Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model. Cell Mol Gastroenterol Hepatol. 2018; 5(4):479-497. PMID: 29930975.
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    31. Yuan J, Tan T, Geng M, Tan G, Chheda C, Pandol SJ. Novel Small Molecule Inhibitors of Protein Kinase D Suppress NF-kappaB Activation and Attenuate the Severity of Rat Cerulein Pancreatitis. Front Physiol. 2017; 8:1014. PMID: 29270134.
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    32. Bharmal SH, Pendharkar SA, Singh RG, Goodarzi MO, Pandol SJ, Petrov MS. Relationship between circulating levels of pancreatic proteolytic enzymes and pancreatic hormones. Pancreatology. 2017 Nov - Dec; 17(6):876-883. PMID: 28958690.
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    33. Lugea A, Waldron RT, Mareninova OA, Shalbueva N, Deng N, Su HY, Thomas DD, Jones EK, Messenger SW, Yang J, Hu C, Gukovsky I, Liu Z, Groblewski GE, Gukovskaya AS, Gorelick FS, Pandol SJ. Human Pancreatic Acinar Cells: Proteomic Characterization, Physiologic Responses, and Organellar Disorders in ex Vivo Pancreatitis. Am J Pathol. 2017 Dec; 187(12):2726-2743. PMID: 28935577.
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    34. Eibl G, Cruz-Monserrate Z, Korc M, Petrov MS, Goodarzi MO, Fisher WE, Habtezion A, Lugea A, Pandol SJ, Hart PA, Andersen DK. Diabetes Mellitus and Obesity as Risk Factors for Pancreatic Cancer. J Acad Nutr Diet. 2018 04; 118(4):555-567. PMID: 28919082.
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    35. Lugea A, Gerloff A, Su HY, Xu Z, Go A, Hu C, French SW, Wilson JS, Apte MV, Waldron RT, Pandol SJ. The Combination of Alcohol and Cigarette Smoke Induces Endoplasmic Reticulum Stress and Cell Death in Pancreatic Acinar Cells. Gastroenterology. 2017 12; 153(6):1674-1686. PMID: 28847752.
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    36. Tomasi ML, Cossu C, Spissu Y, Floris A, Ryoo M, Iglesias-Ara A, Wang Q, Pandol SJ, Bhowmick NA, Seki E, Posadas EM, Lu SC. S-adenosylmethionine and methylthioadenosine inhibit cancer metastasis by targeting microRNA 34a/b-methionine adenosyltransferase 2A/2B axis. Oncotarget. 2017 Oct 03; 8(45):78851-78869. PMID: 29108270.
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    37. Sue LY, Batech M, Yadav D, Pandol SJ, Blumentals WA, von Krusenstiern LS, Chen W, Wu BU. Effect of Serum Triglycerides on Clinical Outcomes in Acute Pancreatitis: Findings From a Regional Integrated Health Care System. Pancreas. 2017 08; 46(7):874-879. PMID: 28697126.
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    38. Lew D, Afghani E, Pandol S. Chronic Pancreatitis: Current Status and Challenges for Prevention and Treatment. Dig Dis Sci. 2017 07; 62(7):1702-1712. PMID: 28501969.
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    39. Wu BU, Batech M, Quezada M, Lew D, Fujikawa K, Kung J, Jamil LH, Chen W, Afghani E, Reicher S, Buxbaum J, Pandol SJ. Dynamic Measurement of Disease Activity in Acute Pancreatitis: The Pancreatitis Activity Scoring System. Am J Gastroenterol. 2017 Jul; 112(7):1144-1152. PMID: 28462914.
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    40. Setiawan VW, Monroe KR, Pandol SJ. Reply. Clin Gastroenterol Hepatol. 2017 07; 15(7):1139. PMID: 28377072.
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    41. Sheth SG, Conwell DL, Whitcomb DC, Alsante M, Anderson MA, Barkin J, Brand R, Cote GA, Freedman SD, Gelrud A, Gorelick F, Lee LS, Morgan K, Pandol S, Singh VK, Yadav D, Wilcox CM, Hart PA. Academic Pancreas Centers of Excellence: Guidance from a multidisciplinary chronic pancreatitis working group at PancreasFest. Pancreatology. 2017 May - Jun; 17(3):419-430. PMID: 28268158.
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    42. Afghani E, Lo SK, Covington PS, Cash BD, Pandol SJ. Sphincter of Oddi Function and Risk Factors for Dysfunction. Front Nutr. 2017; 4:1. PMID: 28194398.
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    43. Setiawan VW, Monroe K, Lugea A, Yadav D, Pandol S. Uniting Epidemiology and Experimental Disease Models for Alcohol-Related Pancreatic Disease. Alcohol Res. 2017; 38(2):173-182. PMID: 28988572.
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    44. Birtolo C, Pham H, Morvaridi S, Chheda C, Go VL, Ptasznik A, Edderkaoui M, Weisman MH, Noss E, Brenner MB, Larson B, Guindi M, Wang Q, Pandol SJ. Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration. Am J Pathol. 2017 Jan; 187(1):146-155. PMID: 27855278.
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    45. Hart PA, Bellin MD, Andersen DK, Bradley D, Cruz-Monserrate Z, Forsmark CE, Goodarzi MO, Habtezion A, Korc M, Kudva YC, Pandol SJ, Yadav D, Chari ST. Type 3c (pancreatogenic) diabetes mellitus secondary to chronic pancreatitis and pancreatic cancer. Lancet Gastroenterol Hepatol. 2016 11; 1(3):226-237. PMID: 28404095.
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    46. Yang J, Waldron RT, Su HY, Moro A, Chang HH, Eibl G, Ferreri K, Kandeel FR, Lugea A, Li L, Pandol SJ. Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G675-G687. PMID: 27609771.
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    47. Setiawan VW, Pandol SJ, Porcel J, Wei PC, Wilkens LR, Le Marchand L, Pike MC, Monroe KR. Dietary Factors Reduce Risk of Acute Pancreatitis in a Large Multiethnic Cohort. Clin Gastroenterol Hepatol. 2017 02; 15(2):257-265.e3. PMID: 27609706.
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    48. Gukovskaya AS, Pandol SJ, Gukovsky I. New insights into the pathways initiating and driving pancreatitis. Curr Opin Gastroenterol. 2016 Sep; 32(5):429-435. PMID: 27428704.
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    49. Pham H, Birtolo C, Chheda C, Yang W, Rodriguez MD, Liu ST, Gugliotta G, Lewis MS, Cirulli V, Pandol SJ, Ptasznik A. Essential Role of Lyn in Fibrosis. Front Physiol. 2016; 7:387. PMID: 27630579.
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    50. Wang R, Chu GCY, Mrdenovic S, Annamalai AA, Hendifar AE, Nissen NN, Tomlinson JS, Lewis M, Palanisamy N, Tseng HR, Posadas EM, Freeman MR, Pandol SJ, Zhau HE, Chung LWK. Cultured circulating tumor cells and their derived xenografts for personalized oncology. Asian J Urol. 2016 Oct; 3(4):240-253. PMID: 29264192.
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    51. Pandol SJ, Forsmark CE, Hart PA. Acceleration of our understanding of recurrent acute and chronic pancreatitis. Pancreatology. 2016 Sep-Oct; 16(5):692-3. PMID: 27542963.
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    52. Setiawan VW, Pandol SJ, Porcel J, Wilkens LR, Le Marchand L, Pike MC, Monroe KR. Prospective Study of Alcohol Drinking, Smoking, and Pancreatitis: The Multiethnic Cohort. Pancreas. 2016 07; 45(6):819-25. PMID: 27171516.
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    53. Pham H, Hui H, Morvaridi S, Cai J, Zhang S, Tan J, Wu V, Levin N, Knudsen B, Goddard WA, Pandol SJ, Abrol R. A bitter pill for type 2 diabetes? The activation of bitter taste receptor TAS2R38 can stimulate GLP-1 release from enteroendocrine L-cells. Biochem Biophys Res Commun. 2016 07 01; 475(3):295-300. PMID: 27208775.
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    54. Matsushita H, Yang YM, Pandol SJ, Seki E. Exosome Migration Inhibitory Factor as a Marker and Therapeutic Target for Pancreatic Cancer. Gastroenterology. 2016 Apr; 150(4):1033-5. PMID: 26922869.
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    55. Edderkaoui M, Xu S, Chheda C, Morvaridi S, Hu RW, Grippo PJ, Mascariñas E, Principe DR, Knudsen B, Xue J, Habtezion A, Uyeminami D, Pinkerton KE, Pandol SJ. HDAC3 mediates smoking-induced pancreatic cancer. Oncotarget. 2016 Feb 16; 7(7):7747-60. PMID: 26745602.
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    56. Yuan J, Pandol SJ. PKD signaling and pancreatitis. J Gastroenterol. 2016 Jul; 51(7):651-9. PMID: 26879861.
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    57. Su HY, Waldron RT, Gong R, Ramanujan VK, Pandol SJ, Lugea A. The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells. PLoS One. 2016; 11(2):e0148999. PMID: 26849807.
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    58. Birtolo C, Go VL, Ptasznik A, Eibl G, Pandol SJ. Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 Jan; 45(1):21-31. PMID: 26658038.
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    59. Morvaridi S, Dhall D, Greene MI, Pandol SJ, Wang Q. Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis. Sci Rep. 2015 Nov 16; 5:16759. PMID: 26567630.
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    60. Suraweera DB, Weeratunga AN, Hu RW, Pandol SJ, Hu R. Alcoholic hepatitis: The pivotal role of Kupffer cells. World J Gastrointest Pathophysiol. 2015 Nov 15; 6(4):90-8. PMID: 26600966.
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    61. Afghani E, Pandol SJ, Shimosegawa T, Sutton R, Wu BU, Vege SS, Gorelick F, Hirota M, Windsor J, Lo SK, Freeman ML, Lerch MM, Tsuji Y, Melmed GY, Wassef W, Mayerle J. Acute Pancreatitis-Progress and Challenges: A Report on an International Symposium. Pancreas. 2015 Nov; 44(8):1195-210. PMID: 26465949.
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    62. Xu S, Chheda C, Ouhaddi Y, Benhaddou H, Bourhim M, Grippo PJ, Principe DR, Mascariñas E, DeCant B, Tsukamoto H, Pandol SJ, Edderkaoui M. Characterization of Mouse Models of Early Pancreatic Lesions Induced by Alcohol and Chronic Pancreatitis. Pancreas. 2015 Aug; 44(6):882-7. PMID: 26166469.
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    63. Wu BU, Chang J, Jeon CY, Pandol SJ, Huang B, Ngor EW, Difronzo AL, Cooper RM. Impact of statin use on survival in patients undergoing resection for early-stage pancreatic cancer. Am J Gastroenterol. 2015 Aug; 110(8):1233-9. PMID: 26195180.
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    64. Pandol SJ, Edderkaoui M. What are the macrophages and stellate cells doing in pancreatic adenocarcinoma? Front Physiol. 2015; 6:125. PMID: 26029109.
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    65. Jeon CY, Pandol SJ, Wu B, Cook-Wiens G, Gottlieb RA, Merz CN, Merz NB, Goodman MT. The association of statin use after cancer diagnosis with survival in pancreatic cancer patients: a SEER-medicare analysis. PLoS One. 2015; 10(4):e0121783. PMID: 25830309.
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    66. Lugea A, Waldron RT, Pandol SJ. Pancreatic adaptive responses in alcohol abuse: Role of the unfolded protein response. Pancreatology. 2015 Jul; 15(4 Suppl):S1-5. PMID: 25736240.
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    67. Gong J, Robbins LA, Lugea A, Waldron RT, Jeon CY, Pandol SJ. Diabetes, pancreatic cancer, and metformin therapy. Front Physiol. 2014; 5:426. PMID: 25426078.
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    68. Pandol SJ. 2014 American Pancreatic Association presidential address. Pancreas. 2014 Nov; 43(8):1129. PMID: 25333393.
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    69. Liu Y, Yuan J, Tan T, Jia W, Lugea A, Mareninova O, Waldron RT, Pandol SJ. Genetic inhibition of protein kinase Ce attenuates necrosis in experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2014 Sep 01; 307(5):G550-63. PMID: 25035113.
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    70. Zhou G, Sinnett-Smith J, Liu SH, Yu J, Wu J, Sanchez R, Pandol SJ, Abrol R, Nemunaitis J, Rozengurt E, Brunicardi FC. Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin. Front Physiol. 2014; 5:226. PMID: 25009500.
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    71. Wu BU, Pandol SJ, Liu IL. Simvastatin is associated with reduced risk of acute pancreatitis: findings from a regional integrated healthcare system. Gut. 2015 Jan; 64(1):133-8. PMID: 24742713.
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    72. Tan CR, Yaffee PM, Jamil LH, Lo SK, Nissen N, Pandol SJ, Tuli R, Hendifar AE. Pancreatic cancer cachexia: a review of mechanisms and therapeutics. Front Physiol. 2014; 5:88. PMID: 24624094.
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    73. Liu ST, Pham H, Pandol SJ, Ptasznik A. Src as the link between inflammation and cancer. Front Physiol. 2013; 4:416. PMID: 24474940.
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    74. Edderkaoui M, Lugea A, Hui H, Eibl G, Lu QY, Moro A, Lu X, Li G, Go VL, Pandol SJ. Ellagic acid and embelin affect key cellular components of pancreatic adenocarcinoma, cancer, and stellate cells. Nutr Cancer. 2013; 65(8):1232-44. PMID: 24127740.
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    75. Park CH, Lee IS, Grippo P, Pandol SJ, Gukovskaya AS, Edderkaoui M. Akt kinase mediates the prosurvival effect of smoking compounds in pancreatic ductal cells. Pancreas. 2013 May; 42(4):655-62. PMID: 23271397.
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    76. Lu QY, Zhang L, Lugea A, Moro A, Edderkaoui M, Eibl G, Pandol SJ, Go VL. Determination of Rottlerin, a Natural Protein Kinases C Inhibitor, in Pancreatic Cancer Cells and Mouse Xenografts by RP-HPLC Method. J Chromatogr Sep Tech. 2013 Jan 01; 4(1). PMID: 24482742.
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    86. Pandol SJ, Gorelick FS, Lugea A. Environmental and genetic stressors and the unfolded protein response in exocrine pancreatic function - a hypothesis. Front Physiol. 2011; 2:8. PMID: 21483727.
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    90. Ye R, Mareninova OA, Barron E, Wang M, Hinton DR, Pandol SJ, Lee AS. Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis. Am J Pathol. 2010 Dec; 177(6):2827-36. PMID: 20971738.
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    96. Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA, Yokosuka O, Pandol SJ, Gukovskaya AS. Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family. Am J Physiol Gastrointest Liver Physiol. 2010 Jan; 298(1):G63-73. PMID: 19762431.
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    97. Sung KF, Odinokova IV, Mareninova OA, Rakonczay Z, Hegyi P, Pandol SJ, Gukovsky I, Gukovskaya AS. Prosurvival Bcl-2 proteins stabilize pancreatic mitochondria and protect against necrosis in experimental pancreatitis. Exp Cell Res. 2009 Jul 01; 315(11):1975-89. PMID: 19331832.
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    102. Lee JK, Edderkaoui M, Truong P, Ohno I, Jang KT, Berti A, Pandol SJ, Gukovskaya AS. NADPH oxidase promotes pancreatic cancer cell survival via inhibiting JAK2 dephosphorylation by tyrosine phosphatases. Gastroenterology. 2007 Nov; 133(5):1637-48. PMID: 17983808.
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    103. Edderkaoui M, Hong P, Lee JK, Pandol SJ, Gukovskaya AS. Insulin-like growth factor-I receptor mediates the prosurvival effect of fibronectin. J Biol Chem. 2007 Sep 14; 282(37):26646-55. PMID: 17627944.
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    104. Hu R, Wang YL, Edderkaoui M, Lugea A, Apte MV, Pandol SJ. Ethanol augments PDGF-induced NADPH oxidase activity and proliferation in rat pancreatic stellate cells. Pancreatology. 2007; 7(4):332-40. PMID: 17627098.
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    109. Lugea A, Nan L, French SW, Bezerra JA, Gukovskaya AS, Pandol SJ. Pancreas recovery following cerulein-induced pancreatitis is impaired in plasminogen-deficient mice. Gastroenterology. 2006 Sep; 131(3):885-99. PMID: 16952557.
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    110. Wang YL, Hu R, Lugea A, Gukovsky I, Smoot D, Gukovskaya AS, Pandol SJ. Ethanol feeding alters death signaling in the pancreas. Pancreas. 2006 May; 32(4):351-9. PMID: 16670617.
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    111. Satoh A, Gukovskaya AS, Reeve JR, Shimosegawa T, Pandol SJ. Ethanol sensitizes NF-kappaB activation in pancreatic acinar cells through effects on protein kinase C-epsilon. Am J Physiol Gastrointest Liver Physiol. 2006 Sep; 291(3):G432-8. PMID: 16574982.
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    114. Satoh A, Gukovskaya AS, Edderkaoui M, Daghighian MS, Reeve JR, Shimosegawa T, Pandol SJ. Tumor necrosis factor-alpha mediates pancreatitis responses in acinar cells via protein kinase C and proline-rich tyrosine kinase 2. Gastroenterology. 2005 Aug; 129(2):639-51. PMID: 16083718.
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    115. Edderkaoui M, Hong P, Vaquero EC, Lee JK, Fischer L, Friess H, Buchler MW, Lerch MM, Pandol SJ, Gukovskaya AS. Extracellular matrix stimulates reactive oxygen species production and increases pancreatic cancer cell survival through 5-lipoxygenase and NADPH oxidase. Am J Physiol Gastrointest Liver Physiol. 2005 Dec; 289(6):G1137-47. PMID: 16037546.
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    116. Go VL, Gukovskaya A, Pandol SJ. Alcohol and pancreatic cancer. Alcohol. 2005 Apr; 35(3):205-11. PMID: 16054982.
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    117. Gukovskaya AS, Pandol SJ. Cell death pathways in pancreatitis and pancreatic cancer. Pancreatology. 2004; 4(6):567-86. PMID: 15550766.
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    118. Pandol SJ. Neurohumoral control of exocrine pancreatic secretion. Curr Opin Gastroenterol. 2004 Sep; 20(5):435-8. PMID: 15689675.
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    120. Satoh A, Gukovskaya AS, Nieto JM, Cheng JH, Gukovsky I, Reeve JR, Shimosegawa T, Pandol SJ. PKC-delta and -epsilon regulate NF-kappaB activation induced by cholecystokinin and TNF-alpha in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2004 Sep; 287(3):G582-91. PMID: 15117677.
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    121. Gukovsky I, Cheng JH, Nam KJ, Lee OT, Lugea A, Fischer L, Penninger JM, Pandol SJ, Gukovskaya AS. Phosphatidylinositide 3-kinase gamma regulates key pathologic responses to cholecystokinin in pancreatic acinar cells. Gastroenterology. 2004 Feb; 126(2):554-66. PMID: 14762792.
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    122. Lugea A, Gukovsky I, Gukovskaya AS, Pandol SJ. Nonoxidative ethanol metabolites alter extracellular matrix protein content in rat pancreas. Gastroenterology. 2003 Dec; 125(6):1845-59. PMID: 14724836.
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    123. Pandol SJ, Gukovsky I, Satoh A, Lugea A, Gukovskaya AS. Animal and in vitro models of alcoholic pancreatitis: role of cholecystokinin. Pancreas. 2003 Nov; 27(4):297-300. PMID: 14576490.
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    124. Vaquero EC, Edderkaoui M, Nam KJ, Gukovsky I, Pandol SJ, Gukovskaya AS. Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways. Gastroenterology. 2003 Oct; 125(4):1188-202. PMID: 14517801.
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    125. Gukovskaya AS, Hosseini S, Satoh A, Cheng JH, Nam KJ, Gukovsky I, Pandol SJ. Ethanol differentially regulates NF-kappaB activation in pancreatic acinar cells through calcium and protein kinase C pathways. Am J Physiol Gastrointest Liver Physiol. 2004 Feb; 286(2):G204-13. PMID: 12958018.
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    129. Gukovsky I, Reyes CN, Vaquero EC, Gukovskaya AS, Pandol SJ. Curcumin ameliorates ethanol and nonethanol experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2003 Jan; 284(1):G85-95. PMID: 12488237.
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    130. Lu SC, Gukovsky I, Lugea A, Reyes CN, Huang ZZ, Chen L, Mato JM, Bottiglieri T, Pandol SJ. Role of S-adenosylmethionine in two experimental models of pancreatitis. FASEB J. 2003 Jan; 17(1):56-8. PMID: 12424217.
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    132. Mouria M, Gukovskaya AS, Jung Y, Buechler P, Hines OJ, Reber HA, Pandol SJ. Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosis. Int J Cancer. 2002 Apr 10; 98(5):761-9. PMID: 11920648.
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    133. Gukovskaya AS, Vaquero E, Zaninovic V, Gorelick FS, Lusis AJ, Brennan ML, Holland S, Pandol SJ. Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis. Gastroenterology. 2002 Apr; 122(4):974-84. PMID: 11910350.
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