Miklos Sahin-Toth

Title(s)Professor-in-Residence, Surgery
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    Miklos Sahin-Toth, M.D., Ph.D., holds the Garry Shandling Chair in Pancreatic Diseases.

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    Trypsin-dependent mechanisms in pancreatitis
    NIH R01DK117809Jul 1, 2018 - Mar 31, 2023
    Role: Principal Investigator
    Digestive enzyme misfolding promotes alcoholic pancreatitis
    NIH R21AA026456Feb 15, 2018 - Jan 31, 2020
    Role: Principal Investigator
    Pancreatic elastases
    NIH R01DK095753Jan 1, 2013 - Dec 31, 2017
    Role: Principal Investigator
    Chymotrypsin C in pancreatitis
    NIH R01DK082412Dec 1, 2008 - Dec 31, 2024
    Role: Principal Investigator
    Role of trypsinogen sulfation in alcoholic pancreatitis
    NIH R21AA014544Sep 20, 2005 - Aug 31, 2008
    Role: Principal Investigator
    Molecular pathomechanism of hereditary pancreatitis
    NIH R01DK058088Jul 1, 2000 - Jun 30, 2021
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2021 12 01; 321(6):G719-G734. Orekhova A, Németh BC, Jancsó Z, Geisz A, Mosztbacher D, Demcsák A, Sahin-Tóth M. PMID: 34643096; PMCID: PMC8668397.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    2. Channelopathy of the Pancreas Causes Chronic Pancreatitis. Gastroenterology. 2020 05; 158(6):1538-1540. Sahin-Tóth M. PMID: 32205170; PMCID: PMC7751598.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    3. Changing the lactose permease of Escherichia coli into a galactose-specific symporter. Proc Natl Acad Sci U S A. 2002 May 14; 99(10):6613-8. Guan L, Sahin-Toth M, Kaback HR. PMID: 12011425; PMCID: PMC124451.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    4. Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen. J Biol Chem. 2002 Feb 15; 277(7):5404-10. Simon P, Weiss FU, Sahin-Toth M, Parry M, Nayler O, Lenfers B, Schnekenburger J, Mayerle J, Domschke W, Lerch MM. PMID: 11719509.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    5. Arg-302 facilitates deprotonation of Glu-325 in the transport mechanism of the lactose permease from Escherichiacoli. Proc Natl Acad Sci U S A. 2001 May 22; 98(11):6068-73. Sahin-Toth M, Kaback HR. PMID: 11353849; PMCID: PMC33423.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
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