Miklos Sahin-Toth

Title(s)	Professor-in-Residence, Surgery
School	Medicine
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Overview

overview

Miklos Sahin-Toth, M.D., Ph.D., holds the Garry Shandling Chair in Pancreatic Diseases.

Research

research activities and funding

Trypsin-dependent mechanisms in pancreatitis
NIH R01DK117809Jul 1, 2018 - Mar 31, 2023
Role: Principal Investigator

Digestive enzyme misfolding promotes alcoholic pancreatitis
NIH R21AA026456Feb 15, 2018 - Jan 31, 2020
Role: Principal Investigator

Pancreatic elastases
NIH R01DK095753Jan 1, 2013 - Dec 31, 2017
Role: Principal Investigator

Chymotrypsin C in pancreatitis
NIH R01DK082412Dec 1, 2008 - Dec 31, 2024
Role: Principal Investigator

Role of trypsinogen sulfation in alcoholic pancreatitis
NIH R21AA014544Sep 20, 2005 - Aug 31, 2008
Role: Principal Investigator

Molecular pathomechanism of hereditary pancreatitis
NIH R01DK058088Jul 1, 2000 - Jun 30, 2021
Role: Principal Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Secretagogue-induced pancreatitis in mice devoid of chymotrypsin. Am J Physiol Gastrointest Liver Physiol. 2024 Sep 01; 327(3):G333-G344. Demcsák A, Shariatzadeh S, Sahin-Tóth M. PMID: 38981616; PMCID: PMC11427105.

View in: PubMed Mentions: 1 Fields:
Gas Gastroenterology Phy Physiology
Translation:Animals
Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2021 12 01; 321(6):G719-G734. Orekhova A, Németh BC, Jancsó Z, Geisz A, Mosztbacher D, Demcsák A, Sahin-Tóth M. PMID: 34643096; PMCID: PMC8668397.

View in: PubMed Mentions: 2 Fields:
Gas Gastroenterology Phy Physiology
Translation:Animals Cells
Channelopathy of the Pancreas Causes Chronic Pancreatitis. Gastroenterology. 2020 05; 158(6):1538-1540. Sahin-Tóth M. PMID: 32205170; PMCID: PMC7751598.

View in: PubMed Mentions: 7 Fields:
Gas Gastroenterology
Translation:Humans Cells
Changing the lactose permease of Escherichia coli into a galactose-specific symporter. Proc Natl Acad Sci U S A. 2002 May 14; 99(10):6613-8. Guan L, Sahin-Toth M, Kaback HR. PMID: 12011425; PMCID: PMC124451.

View in: PubMed Mentions: 12 Fields:
Sci Science
Translation:Cells
Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen. J Biol Chem. 2002 Feb 15; 277(7):5404-10. Simon P, Weiss FU, Sahin-Toth M, Parry M, Nayler O, Lenfers B, Schnekenburger J, Mayerle J, Domschke W, Lerch MM. PMID: 11719509.

View in: PubMed Mentions: 27 Fields:
Bio Biochemistry
Translation:Humans Cells
Arg-302 facilitates deprotonation of Glu-325 in the transport mechanism of the lactose permease from Escherichiacoli. Proc Natl Acad Sci U S A. 2001 May 22; 98(11):6068-73. Sahin-Toth M, Kaback HR. PMID: 11353849; PMCID: PMC33423.

View in: PubMed Mentions: 23 Fields:
Sci Science
Translation:Cells