Nicolas Musi

Title(s)Professor-in-residence, Medicine
SchoolMedicine
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evaluation of Exploratory Fluid Biomarker Results from a Phase 1 Senolytic Trial in Mild Alzheimer's Disease. Res Sq. 2024 Mar 08. Garbarino VR, Palavicini JP, Melendez J, Barthelemy N, He Y, Kautz TF, Lopez-Cruzan M, Mathews JJ, Xu P, Zhan B, Saliba A, Ragi N, Sharma K, Craft S, Petersen RC, Espindola-Netto JM, Xue A, Tchkonia T, Kirkland JL, Seshadri S, Salardini A, Musi N, Bateman RJ, Gonzales MM, Orr ME. PMID: 38496619; PMCID: PMC10942554.
      View in: PubMed   Mentions:
    2. A pilot study to investigate the safety and feasibility of antiretroviral therapy for Alzheimer's disease (ART-AD). medRxiv. 2024 Feb 28. Sullivan AC, Zuniga G, Ramirez P, Fernandez R, Wang CP, Li J, Davila L, Pelton K, Gomez S, Sohn C, Gonzalez E, Lopez-Cruzan M, Gonzalez DA, Parker A, Zilli E, de Erausquin GA, Seshadri S, Espinoza S, Musi N, Frost B. PMID: 38464267; PMCID: PMC10925371.
      View in: PubMed   Mentions:
    3. A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment. Geroscience. 2024 Feb; 46(1):665-682. Orr ME, Kotkowski E, Ramirez P, Bair-Kelps D, Liu Q, Brenner C, Schmidt MS, Fox PT, Larbi A, Tan C, Wong G, Gelfond J, Frost B, Espinoza S, Musi N, Powers B. PMID: 37994989; PMCID: PMC10828186.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Correction: the clinical significance of binge eating among older adult women: an investigation into health correlates, psychological wellbeing, and quality of life. J Eat Disord. 2023 Nov 15; 11(1):203. Kilpela LS, Marshall VB, Keel PK, LaCroix AZ, Espinoza SE, Hooper SC, Musi N. PMID: 37968703; PMCID: PMC10648719.
      View in: PubMed   Mentions:
    5. Skeletal muscle TFEB signaling promotes central nervous system function and reduces neuroinflammation during aging and neurodegenerative disease. Cell Rep. 2023 11 28; 42(11):113436. Matthews I, Birnbaum A, Gromova A, Huang AW, Liu K, Liu EA, Coutinho K, McGraw M, Patterson DC, Banks MT, Nobles AC, Nguyen N, Merrihew GE, Wang L, Baeuerle E, Fernandez E, Musi N, MacCoss MJ, Miranda HC, La Spada AR, Cortes CJ. PMID: 37952157; PMCID: PMC10841857.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    6. Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns. Endocr Rev. 2023 11 09; 44(6):1047-1073. Bhasin S, Seals D, Migaud M, Musi N, Baur JA. PMID: 37364580.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Senolytic therapy in mild Alzheimer's disease: a phase 1 feasibility trial. Nat Med. 2023 Oct; 29(10):2481-2488. Gonzales MM, Garbarino VR, Kautz TF, Palavicini JP, Lopez-Cruzan M, Dehkordi SK, Mathews JJ, Zare H, Xu P, Zhang B, Franklin C, Habes M, Craft S, Petersen RC, Tchkonia T, Kirkland JL, Salardini A, Seshadri S, Musi N, Orr ME. PMID: 37679434; PMCID: PMC10875739.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    8. NAD-elevating Interventions for Cardiometabolic Disease. J Clin Endocrinol Metab. 2023 08 18; 108(9):e897-e898. Musi N. PMID: 36869827.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop. J Gerontol A Biol Sci Med Sci. 2023 06 16; 78(Suppl 1):53-60. Espinoza SE, Khosla S, Baur JA, de Cabo R, Musi N. PMID: 37325957; PMCID: PMC10272987.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Targeting hepatic serine-arginine protein kinase 2 ameliorates alcohol-associated liver disease by alternative splicing control of lipogenesis. Hepatology. 2023 11 01; 78(5):1506-1524. Li G, Chen H, Shen F, Smithson SB, Shealy GL, Ping Q, Liang Z, Han J, Adams AC, Li Y, Feng D, Gao B, Morita M, Han X, Huang TH, Musi N, Zang M. PMID: 37129868; PMCID: PMC10592686.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    11. Senolytic therapy to modulate the progression of Alzheimer's Disease (SToMP-AD) - Outcomes from the first clinical trial of senolytic therapy for Alzheimer's disease. Res Sq. 2023 Apr 24. Gonzales MM, Garbarino VR, Kautz T, Palavicini JP, Lopez-Cruzan M, Dehkordi SK, Mathews J, Zare H, Xu P, Zhang B, Franklin C, Habes M, Craft S, Petersen RC, Tchkonia T, Kirkland J, Salardini A, Seshadri S, Musi N, Orr ME. PMID: 37162971; PMCID: PMC10168460.
      View in: PubMed   Mentions:
    12. Binge eating age of onset, frequency, and associated emotional distress among women aged 60 years and over. Eat Disord. 2023 Sep 03; 31(5):479-486. Kilpela LS, Marshall VB, Hooper SC, Becker CB, Keel PK, LaCroix AZ, Musi N, Espinoza SE. PMID: 37039323; PMCID: PMC10876154.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Age-dependent loss of hepatic SIRT1 enhances NLRP3 inflammasome signaling and impairs capacity for liver fibrosis resolution. Aging Cell. 2023 05; 22(5):e13811. Adjei-Mosi J, Sun Q, Smithson SB, Shealy GL, Amerineni KD, Liang Z, Chen H, Wang M, Ping Q, Han J, Morita M, Kamat A, Musi N, Zang M. PMID: 36999514; PMCID: PMC10186605.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    14. microRNA-449a reduces growth hormone-stimulated senescent cell burden through PI3K-mTOR signaling. Proc Natl Acad Sci U S A. 2023 04 04; 120(14):e2213207120. Noureddine S, Nie J, Schneider A, Menon V, Fliesen Z, Dhahbi J, Victoria B, Oyer J, Robles-Carrillo L, Nunes ADC, Ashiqueali S, Janusz A, Copik A, Robbins PD, Musi N, Masternak MM. PMID: 36976763; PMCID: PMC10083567.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    15. Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability. EBioMedicine. 2023 Apr; 90:104481. Nambiar A, Kellogg D, Justice J, Goros M, Gelfond J, Pascual R, Hashmi S, Masternak M, Prata L, LeBrasseur N, Limper A, Kritchevsky S, Musi N, Tchkonia T, Kirkland J. PMID: 36857968; PMCID: PMC10006434.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    16. Effects of an exogenous ketone ester using multi-omics in skeletal muscle of aging C57BL/6J male mice. Front Nutr. 2022; 9:1041026. Roberts BM, Deemer SE, Smith DL, Mobley JA, Musi N, Plaisance EP. PMID: 36458175; PMCID: PMC9707703.
      View in: PubMed   Mentions: 4  
    17. Effect of acute TLR4 inhibition on insulin resistance in humans. J Clin Invest. 2022 11 01; 132(21). Liang H, Sathavarodom N, Colmenares C, Gelfond J, Espinoza SE, Ganapathy V, Musi N. PMID: 36066991; PMCID: PMC9621129.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. The clinical significance of binge eating among older adult women: an investigation into health correlates, psychological wellbeing, and quality of life. J Eat Disord. 2022 Jul 07; 10(1):97. Kilpela LS, Marshall VB, Keel PK, LaCroix AZ, Espinoza SE, Hooper SC, Musi N. PMID: 35799222; PMCID: PMC9264536.
      View in: PubMed   Mentions: 1  
    19. Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure. Cell Metab. 2022 04 05; 34(4):564-580.e8. Katsumura S, Siddiqui N, Goldsmith MR, Cheah JH, Fujikawa T, Minegishi G, Yamagata A, Yabuki Y, Kobayashi K, Shirouzu M, Inagaki T, Huang TH, Musi N, Topisirovic I, Larsson O, Morita M. PMID: 35385705; PMCID: PMC9386786.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    20. Exercise and Creatine Supplementation to Augment the Adaptation of Exercise Training Among Breast Cancer Survivors Completing Chemotherapy: Protocol for an Open-label Randomized Controlled Trial (the THRIVE Study). JMIR Res Protoc. 2022 Apr 01; 11(4):e26827. Patel DI, Gonzalez A, Moon C, Serra M, Bridges PB, Hughes D, Clarke G, Kilpela L, Jiwani R, Musi N. PMID: 35363152; PMCID: PMC9015753.
      View in: PubMed   Mentions: 1  
    21. Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans. EBioMedicine. 2022 Mar; 77:103912. Zhu Y, Prata LGPL, Gerdes EOW, Netto JME, Pirtskhalava T, Giorgadze N, Tripathi U, Inman CL, Johnson KO, Xue A, Palmer AK, Chen T, Schaefer K, Justice JN, Nambiar AM, Musi N, Kritchevsky SB, Chen J, Khosla S, Jurk D, Schafer MJ, Tchkonia T, Kirkland JL. PMID: 35292270; PMCID: PMC9034457.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    22. Stress-Busting Program for Family Caregivers: Validation of the Spanish version using biomarkers and quality-of-life measures. Res Nurs Health. 2022 04; 45(2):205-217. Arévalo-Flechas LC, Flores BP, Wang H, Liang H, Li Y, Gelfond J, Espinoza S, Lewis SL, Musi N, Yeh CK. PMID: 35174517.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD): A Pilot Clinical Trial. J Prev Alzheimers Dis. 2022; 9(1):22-29. Gonzales MM, Garbarino VR, Marques Zilli E, Petersen RC, Kirkland JL, Tchkonia T, Musi N, Seshadri S, Craft S, Orr ME. PMID: 35098970; PMCID: PMC8612719.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCTClinical Trials
    24. Binge eating among older women: prevalence rates and health correlates across three independent samples. J Eat Disord. 2021 Oct 19; 9(1):132. Wilfred SA, Becker CB, Kanzler KE, Musi N, Espinoza SE, Kilpela LS. PMID: 34666821; PMCID: PMC8524882.
      View in: PubMed   Mentions: 5  
    25. Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era. J Am Geriatr Soc. 2021 11; 69(11):3023-3033. Verdoorn BP, Evans TK, Hanson GJ, Zhu Y, Langhi Prata LGP, Pignolo RJ, Atkinson EJ, Wissler-Gerdes EO, Kuchel GA, Mannick JB, Kritchevsky SB, Khosla S, Rizza SA, Walston JD, Musi N, Lipsitz LA, Kiel DP, Yung R, LeBrasseur NK, Singh RJ, McCarthy T, Puskarich MA, Niedernhofer LJ, Robbins PD, Sorenson M, Tchkonia T, Kirkland JL. PMID: 34375437; PMCID: PMC8447437.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    26. Cellular Senescence in Idiopathic Pulmonary Fibrosis. Curr Mol Biol Rep. 2021; 7(3):31-40. Kellogg DL, Kellogg DL, Musi N, Nambiar AM. PMID: 34401216; PMCID: PMC8358258.
      View in: PubMed   Mentions: 18  
    27. San Antonio Nathan Shock Center: your one-stop shop for aging research. Geroscience. 2021 10; 43(5):2105-2118. Salmon AB, Nelson JF, Gelfond JAL, Javors M, Ginsburg B, Lopez-Cruzan M, Galvan V, Fernandez E, Musi N, Ikeno Y, Hubbard G, Lechleiter J, Hornsby PJ, Strong R. PMID: 34240333; PMCID: PMC8599539.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    28. Circulating microRNA profile in humans and mice with congenital GH deficiency. Aging Cell. 2021 07; 20(7):e13420. Saccon TD, Schneider A, Marinho CG, Nunes ADC, Noureddine S, Dhahbi J, Nunez Lopez YO, LeMunyan G, Salvatori R, Oliveira CRP, Oliveira-Santos AA, Musi N, Bartke A, Aguiar-Oliveira MH, Masternak MM. PMID: 34118183; PMCID: PMC8282278.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    29. Intranasal Oxytocin Improves Lean Muscle Mass and Lowers LDL Cholesterol in Older Adults with Sarcopenic Obesity: A Pilot Randomized Controlled Trial. J Am Med Dir Assoc. 2021 09; 22(9):1877-1882.e2. Espinoza SE, Lee JL, Wang CP, Ganapathy V, MacCarthy D, Pascucci C, Musi N, Volpi E. PMID: 34029521; PMCID: PMC8567747.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    30. Rapid report on using data to make standardized decisions about enrollment during the COVID-19 pandemic: perspectives from the MoTrPAC study. Ann Epidemiol. 2021 10; 62:19-21. George SM, Chen H, Miller ME, Rejeski WJ, Stowe CL, Webb C, Kraus WE, Musi N, Jakicic JM. PMID: 33957248; PMCID: PMC8089030.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    31. Early disruption of nerve mitochondrial and myelin lipid homeostasis in obesity-induced diabetes. JCI Insight. 2020 11 05; 5(21). Palavicini JP, Chen J, Wang C, Wang J, Qin C, Baeuerle E, Wang X, Woo JA, Kang DE, Musi N, Dupree JL, Han X. PMID: 33148881; PMCID: PMC7710310.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    32. Rapamycin-mediated mouse lifespan extension: Late-life dosage regimes with sex-specific effects. Aging Cell. 2020 11; 19(11):e13269. Strong R, Miller RA, Bogue M, Fernandez E, Javors MA, Libert S, Marinez PA, Murphy MP, Musi N, Nelson JF, Petrascheck M, Reifsnyder P, Richardson A, Salmon AB, Macchiarini F, Harrison DE. PMID: 33145977; PMCID: PMC7681050.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    33. NFκB Regulates Muscle Development and Mitochondrial Function. J Gerontol A Biol Sci Med Sci. 2020 03 09; 75(4):647-653. Valentine JM, Li ME, Shoelson SE, Zhang N, Reddick RL, Musi N. PMID: 30423026; PMCID: PMC7328192.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    34. Acarbose improved survival for Apc+/Min mice. Aging Cell. 2020 02; 19(2):e13088. Dodds SG, Parihar M, Javors M, Nie J, Musi N, Dave Sharp Z, Hasty P. PMID: 31903726; PMCID: PMC6996958.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    35. Rationale and Study Design of a Randomized Clinical Trial of Metformin to Prevent Frailty in Older Adults With Prediabetes. J Gerontol A Biol Sci Med Sci. 2020 01 01; 75(1):102-109. Espinoza SE, Musi N, Wang CP, Michalek J, Orsak B, Romo T, Powers B, Conde A, Moris M, Bair-Kelps D, Li Y, Ganapathy V, Jergensen TE, Kelly LC, Jiwani R. PMID: 30888034; PMCID: PMC7175970.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    36. Nexrutine and exercise similarly prevent high grade prostate tumors in transgenic mouse model. PLoS One. 2019; 14(12):e0226187. Patel DI, Abuchowski K, Bedolla R, Rivas P, Musi N, Reddick R, Kumar AP. PMID: 31856170; PMCID: PMC6922346.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    37. Exercise preserves muscle mass and force in a prostate cancer mouse model. Eur J Transl Myol. 2019 Oct 29; 29(4):8520. Patel DI, Abuchowski K, Sheikh B, Rivas P, Musi N, Kumar AP. PMID: 31908747; PMCID: PMC6926432.
      View in: PubMed   Mentions: 8  
    38. The enigmatic role of growth hormone in age-related diseases, cognition, and longevity. Geroscience. 2019 12; 41(6):759-774. Colon G, Saccon T, Schneider A, Cavalcante MB, Huffman DM, Berryman D, List E, Ikeno Y, Musi N, Bartke A, Kopchick J, Kirkland JL, Tchkonia T, Masternak MM. PMID: 31485887; PMCID: PMC6925094.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    39. Nexrutine® preserves muscle mass similar to exercise in prostate cancer mouse model. Physiol Rep. 2019 08; 7(16):e14217. Patel DI, Wallace D, Abuchowski K, Rivas P, Gallegos A, Musi N, Kumar AP. PMID: 31456341; PMCID: PMC6712237.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    40. Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson's diseases. Aging Cell. 2019 06; 18(3):e12941. Song C, Zhang J, Qi S, Liu Z, Zhang X, Zheng Y, Andersen JP, Zhang W, Strong R, Martinez PA, Musi N, Nie J, Shi Y. PMID: 30838774; PMCID: PMC6516155.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    41. Models and Studies of Aging: Executive Summary of a Report from the U13 Conference Series. J Am Geriatr Soc. 2019 03; 67(3):428-433. Hurria A, Carpenter CR, McFarland F, Lundebjerg NE, de Cabo R, Ferrucci L, Studenski SA, Barzilai N, Briggs JP, Ix JH, Kitzman DW, Kuchel GA, Musi N, Newman JC, Rando TA, Smith AK, Walston JD, Kirkland JL, Yung R. PMID: 30693953; PMCID: PMC6403012.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    42. Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study. EBioMedicine. 2019 Feb; 40:554-563. Justice JN, Nambiar AM, Tchkonia T, LeBrasseur NK, Pascual R, Hashmi SK, Prata L, Masternak MM, Kritchevsky SB, Musi N, Kirkland JL. PMID: 30616998; PMCID: PMC6412088.
      View in: PubMed   Mentions: 428     Fields:    Translation:HumansCTClinical Trials
    43. Effects of intravenous AICAR (5-aminoimidazole-4-carboximide riboside) administration on insulin signaling and resistance in premature baboons, Papio sp. PLoS One. 2018; 13(12):e0208757. Blanco CL, Gastaldelli A, Anzueto DG, Winter LA, Seidner SR, McCurnin DC, Liang H, Javors MA, DeFronzo RA, Musi N. PMID: 30540820; PMCID: PMC6291136.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    44. Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell. 2018 12; 17(6):e12840. Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME. PMID: 30126037; PMCID: PMC6260915.
      View in: PubMed   Mentions: 235     Fields:    Translation:HumansAnimalsCells
    45. SAD-A Promotes Glucose-Stimulated Insulin Secretion Through Phosphorylation and Inhibition of GDIα in Male Islet β Cells. Endocrinology. 2018 08 01; 159(8):3036-3047. Nie J, Sun C, Chang Z, Musi N, Shi Y. PMID: 29873699; PMCID: PMC6693047.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    46. Older Subjects With β-Cell Dysfunction Have an Accentuated Incretin Release. J Clin Endocrinol Metab. 2018 07 01; 103(7):2613-2619. de Jesús Garduno-Garcia J, Gastaldelli A, DeFronzo RA, Lertwattanarak R, Holst JJ, Musi N. PMID: 29672742; PMCID: PMC6669818.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    47. DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease. Hepatology. 2018 08; 68(2):496-514. Chen H, Shen F, Sherban A, Nocon A, Li Y, Wang H, Xu MJ, Rui X, Han J, Jiang B, Lee D, Li N, Keyhani-Nejad F, Fan JG, Liu F, Kamat A, Musi N, Guarente L, Pacher P, Gao B, Zang M. PMID: 29457836; PMCID: PMC6097912.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    48. A low dose lipid infusion is sufficient to induce insulin resistance and a pro-inflammatory response in human subjects. PLoS One. 2018; 13(4):e0195810. Liang H, Lum H, Alvarez A, Garduno-Garcia JJ, Daniel BJ, Musi N. PMID: 29649324; PMCID: PMC5897027.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    49. A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects. Exp Gerontol. 2018 05; 105:53-69. Kraig E, Linehan LA, Liang H, Romo TQ, Liu Q, Wu Y, Benavides AD, Curiel TJ, Javors MA, Musi N, Chiodo L, Koek W, Gelfond JAL, Kellogg DL. PMID: 29408453; PMCID: PMC5869166.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCellsCTClinical Trials
    50. SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice. Diabetologia. 2018 04; 61(4):906-918. Qin K, Zhang N, Zhang Z, Nipper M, Zhu Z, Leighton J, Xu K, Musi N, Wang P. PMID: 29322219; PMCID: PMC6203439.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    51. Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health. Aging Cell. 2017 08; 16(4):847-858. Zhang N, Valentine JM, Zhou Y, Li ME, Zhang Y, Bhattacharya A, Walsh ME, Fischer KE, Austad SN, Osmulski P, Gaczynska M, Shoelson SE, Van Remmen H, Chen HI, Chen Y, Liang H, Musi N. PMID: 28556540; PMCID: PMC5506420.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    52. Hepatic Insulin Resistance and Altered Gluconeogenic Pathway in Premature Baboons. Endocrinology. 2017 05 01; 158(5):1140-1151. McGill-Vargas L, Gastaldelli A, Liang H, Anzueto Guerra D, Johnson-Pais T, Seidner S, McCurnin D, Muscogiuri G, DeFronzo R, Musi N, Blanco C. PMID: 28324053; PMCID: PMC5460827.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    53. IGF-1 receptor haploinsufficiency leads to age-dependent development of metabolic syndrome. Biochem Biophys Res Commun. 2017 05 13; 486(4):937-944. Thakur S, Garg N, Zhang N, Hussey SE, Musi N, Adamo ML. PMID: 28351623.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    54. Exenatide improves both hepatic and adipose tissue insulin resistance: A dynamic positron emission tomography study. Hepatology. 2016 12; 64(6):2028-2037. Gastaldelli A, Gaggini M, Daniele G, Ciociaro D, Cersosimo E, Tripathy D, Triplitt C, Fox P, Musi N, DeFronzo R, Iozzo P. PMID: 27639082.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    55. Pioglitazone is equally effective for diabetes prevention in older versus younger adults with impaired glucose tolerance. Age (Dordr). 2016 Dec; 38(5-6):485-493. Espinoza SE, Wang CP, Tripathy D, Clement SC, Schwenke DC, Banerji MA, Bray GA, Buchanan TA, Henry RR, Kitabchi AE, Mudaliar S, Stentz FB, Reaven PD, DeFronzo RA, Musi N. PMID: 27585671; PMCID: PMC5266219.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    56. Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus: A Randomized Trial. Ann Intern Med. 2016 Sep 06; 165(5):305-15. Cusi K, Orsak B, Bril F, Lomonaco R, Hecht J, Ortiz-Lopez C, Tio F, Hardies J, Darland C, Musi N, Webb A, Portillo-Sanchez P. PMID: 27322798.
      View in: PubMed   Mentions: 349     Fields:    Translation:Humans
    57. Diabetes Incidence and Glucose Tolerance after Termination of Pioglitazone Therapy: Results from ACT NOW. J Clin Endocrinol Metab. 2016 05; 101(5):2056-62. Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Reaven PD, DeFronzo RA. PMID: 26982008; PMCID: PMC6287507.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    58. Pharmacological TLR4 Inhibition Protects against Acute and Chronic Fat-Induced Insulin Resistance in Rats. PLoS One. 2015; 10(7):e0132575. Zhang N, Liang H, Farese RV, Li J, Musi N, Hussey SE. PMID: 26196892; PMCID: PMC4510579.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    59. Exenatide Regulates Cerebral Glucose Metabolism in Brain Areas Associated With Glucose Homeostasis and Reward System. Diabetes. 2015 Oct; 64(10):3406-12. Daniele G, Iozzo P, Molina-Carrion M, Lancaster J, Ciociaro D, Cersosimo E, Tripathy D, Triplitt C, Fox P, Musi N, DeFronzo R, Gastaldelli A. PMID: 26116695; PMCID: PMC6908417.
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    60. A novel insulin resistance index to monitor changes in insulin sensitivity and glucose tolerance: the ACT NOW study. J Clin Endocrinol Metab. 2015 May; 100(5):1855-62. Tripathy D, Cobb JE, Gall W, Adam KP, George T, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Reaven PD, Musi N, Ferrannini E, DeFronzo RA. PMID: 25603459; PMCID: PMC4422894.
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    61. The effect of muraglitazar on adiponectin signalling, mitochondrial function and fat oxidation genes in human skeletal muscle in vivo. Diabet Med. 2015 May; 32(5):657-64. Coletta DK, Fernandez M, Cersosimo E, Gastaldelli A, Musi N, DeFronzo RA. PMID: 25484175; PMCID: PMC6824198.
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    62. Peripheral insulin resistance and impaired insulin signaling contribute to abnormal glucose metabolism in preterm baboons. Endocrinology. 2015 Mar; 156(3):813-23. Blanco CL, McGill-Vargas LL, Gastaldelli A, Seidner SR, McCurnin DC, Leland MM, Anzueto DG, Johnson MC, Liang H, DeFronzo RA, Musi N. PMID: 25560831; PMCID: PMC4330304.
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    63. Acute insulin resistance stimulates and insulin sensitization attenuates vascular smooth muscle cell migration and proliferation. Physiol Rep. 2014 Aug 01; 2(8). Cersosimo E, Xu X, Upala S, Triplitt C, Musi N. PMID: 25138792; PMCID: PMC4246575.
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    64. Diabetes and cardiovascular disease in older adults: current status and future directions. Diabetes. 2014 Aug; 63(8):2578-89. Halter JB, Musi N, McFarland Horne F, Crandall JP, Goldberg A, Harkless L, Hazzard WR, Huang ES, Kirkman MS, Plutzky J, Schmader KE, Zieman S, High KP. PMID: 25060886; PMCID: PMC4113072.
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    65. The disposition index does not reflect β-cell function in IGT subjects treated with pioglitazone. J Clin Endocrinol Metab. 2014 Oct; 99(10):3774-81. DeFronzo RA, Tripathy D, Abdul-Ghani M, Musi N, Gastaldelli A. PMID: 24937535.
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    66. Elevated muscle TLR4 expression and metabolic endotoxemia in human aging. J Gerontol A Biol Sci Med Sci. 2015 Feb; 70(2):232-46. Ghosh S, Lertwattanarak R, Garduño Jde J, Galeana JJ, Li J, Zamarripa F, Lancaster JL, Mohan S, Hussey S, Musi N. PMID: 24846769; PMCID: PMC4311182.
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    67. APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor. Cell Rep. 2014 May 22; 7(4):1227-38. Ryu J, Galan AK, Xin X, Dong F, Abdul-Ghani MA, Zhou L, Wang C, Li C, Holmes BM, Sloane LB, Austad SN, Guo S, Musi N, DeFronzo RA, Deng C, White MF, Liu F, Dong LQ. PMID: 24813896; PMCID: PMC4380268.
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    68. Antenatal corticosteroids alter insulin signaling pathways in fetal baboon skeletal muscle. J Endocrinol. 2014 May; 221(2):253-60. Blanco CL, Moreira AG, McGill-Vargas LL, Anzueto DG, Nathanielsz P, Musi N. PMID: 24756099; PMCID: PMC4347920.
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    69. Baseline adiponectin levels do not influence the response to pioglitazone in ACT NOW. Diabetes Care. 2014 Jun; 37(6):1706-11. Tripathy D, Clement SC, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Gastaldelli A, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Reaven PD, DeFronzo RA. PMID: 24705615; PMCID: PMC4179517.
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    70. A sustained increase in plasma NEFA upregulates the Toll-like receptor network in human muscle. Diabetologia. 2014 Mar; 57(3):582-91. Hussey SE, Lum H, Alvarez A, Cipriani Y, Garduño-Garcia J, Anaya L, Dube J, Musi N. PMID: 24337154; PMCID: PMC3945433.
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    71. Combined acute hyperglycemic and hyperinsulinemic clamp induced profibrotic and proinflammatory responses in the kidney. Am J Physiol Cell Physiol. 2014 Feb 01; 306(3):C202-11. Mariappan MM, DeSilva K, Sorice GP, Muscogiuri G, Jimenez F, Ahuja S, Barnes JL, Choudhury GG, Musi N, DeFronzo R, Kasinath BS. PMID: 24108867; PMCID: PMC3919997.
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    72. Prediction of diabetes based on baseline metabolic characteristics in individuals at high risk. Diabetes Care. 2013 Nov; 36(11):3607-12. Defronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Reaven PD, Gastaldelli A, ACT NOW Study. PMID: 24062330; PMCID: PMC3816921.
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    73. Energy expenditure evaluation in humans and non-human primates by SenseWear Armband. Validation of energy expenditure evaluation by SenseWear Armband by direct comparison with indirect calorimetry. PLoS One. 2013; 8(9):e73651. Casiraghi F, Lertwattanarak R, Luzi L, Chavez AO, Davalli AM, Naegelin T, Comuzzie AG, Frost P, Musi N, Folli F. PMID: 24069218; PMCID: PMC3777938.
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    74. Genetic disruption of SOD1 gene causes glucose intolerance and impairs β-cell function. Diabetes. 2013 Dec; 62(12):4201-7. Muscogiuri G, Salmon AB, Aguayo-Mazzucato C, Li M, Balas B, Guardado-Mendoza R, Giaccari A, Reddick RL, Reyna SM, Weir G, Defronzo RA, Van Remmen H, Musi N. PMID: 24009256; PMCID: PMC3837066.
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    75. Prevention of diabetes with pioglitazone in ACT NOW: physiologic correlates. Diabetes. 2013 Nov; 62(11):3920-6. Defronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Gastaldelli A, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Reaven PD, ACT NOW Study. PMID: 23863810; PMCID: PMC3806596.
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    76. Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle. Nutr Diabetes. 2013 Jun 10; 3:e74. Middelbeek RJ, Chambers MA, Tantiwong P, Treebak JT, An D, Hirshman MF, Musi N, Goodyear LJ. PMID: 23752133; PMCID: PMC3697402.
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    77. Effect of lipopolysaccharide on inflammation and insulin action in human muscle. PLoS One. 2013; 8(5):e63983. Liang H, Hussey SE, Sanchez-Avila A, Tantiwong P, Musi N. PMID: 23704966; PMCID: PMC3660322.
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    78. Effect of pioglitazone on body composition and bone density in subjects with prediabetes in the ACT NOW trial. Diabetes Obes Metab. 2013 Oct; 15(10):931-7. Bray GA, Smith SR, Banerji MA, Tripathy D, Clement SC, Buchanan TA, Henry RR, Kitabchi AE, Mudaliar S, Musi N, Ratner RE, Schwenke DC, Stentz FB, Reaven PD, DeFronzo RA. PMID: 23551856.
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    79. Effect of a sustained reduction in plasma free fatty acid concentration on insulin signalling and inflammation in skeletal muscle from human subjects. J Physiol. 2013 Jun 01; 591(11):2897-909. Liang H, Tantiwong P, Sriwijitkamol A, Shanmugasundaram K, Mohan S, Espinoza S, Defronzo RA, Dubé JJ, Musi N. PMID: 23529132; PMCID: PMC3690693.
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    80. Short-term exercise training improves insulin sensitivity but does not inhibit inflammatory pathways in immune cells from insulin-resistant subjects. J Diabetes Res. 2013; 2013:107805. Reyna SM, Tantiwong P, Cersosimo E, Defronzo RA, Sriwijitkamol A, Musi N. PMID: 23671849; PMCID: PMC3647562.
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    81. Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle. Nat Commun. 2013; 4:1871. Koh HJ, Toyoda T, Didesch MM, Lee MY, Sleeman MW, Kulkarni RN, Musi N, Hirshman MF, Goodyear LJ. PMID: 23695665; PMCID: PMC3707125.
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    82. Improved insulin sensitivity associated with reduced mitochondrial complex IV assembly and activity. FASEB J. 2013 Apr; 27(4):1371-80. Deepa SS, Pulliam D, Hill S, Shi Y, Walsh ME, Salmon A, Sloane L, Zhang N, Zeviani M, Viscomi C, Musi N, Van Remmen H. PMID: 23241310.
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    83. TAK-242, a small-molecule inhibitor of Toll-like receptor 4 signalling, unveils similarities and differences in lipopolysaccharide- and lipid-induced inflammation and insulin resistance in muscle cells. Biosci Rep. 2012 Nov 30; 33(1):37-47. Hussey SE, Liang H, Costford SR, Klip A, DeFronzo RA, Sanchez-Avila A, Ely B, Musi N. PMID: 23050932; PMCID: PMC3522475.
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    84. Pioglitazone slows progression of atherosclerosis in prediabetes independent of changes in cardiovascular risk factors. Arterioscler Thromb Vasc Biol. 2013 Feb; 33(2):393-9. Saremi A, Schwenke DC, Buchanan TA, Hodis HN, Mack WJ, Banerji M, Bray GA, Clement SC, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Tripathy D, DeFronzo RA, Reaven PD. PMID: 23175674; PMCID: PMC3908828.
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    85. Methionine sulfoxide reductase A affects insulin resistance by protecting insulin receptor function. Free Radic Biol Med. 2013 Mar; 56:123-32. Styskal J, Nwagwu FA, Watkins YN, Liang H, Richardson A, Musi N, Salmon AB. PMID: 23089224; PMCID: PMC3578155.
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    86. Reduced AMPK-ACC and mTOR signaling in muscle from older men, and effect of resistance exercise. Mech Ageing Dev. 2012 Nov-Dec; 133(11-12):655-64. Li M, Verdijk LB, Sakamoto K, Ely B, van Loon LJ, Musi N. PMID: 23000302; PMCID: PMC3631591.
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    87. Disruption of growth factor receptor-binding protein 10 in the pancreas enhances β-cell proliferation and protects mice from streptozotocin-induced β-cell apoptosis. Diabetes. 2012 Dec; 61(12):3189-98. Zhang J, Zhang N, Liu M, Li X, Zhou L, Huang W, Xu Z, Liu J, Musi N, DeFronzo RA, Cunningham JM, Zhou Z, Lu XY, Liu F. PMID: 22923474; PMCID: PMC3501856.
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    88. Fat-specific DsbA-L overexpression promotes adiponectin multimerization and protects mice from diet-induced obesity and insulin resistance. Diabetes. 2012 Nov; 61(11):2776-86. Liu M, Xiang R, Wilk SA, Zhang N, Sloane LB, Azarnoush K, Zhou L, Chen H, Xiang G, Walter CA, Austad SN, Musi N, DeFronzo RA, Asmis R, Scherer PE, Dong LQ, Liu F. PMID: 22807031; PMCID: PMC3478538.
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    89. Effect of acute exercise on glycogen synthase in muscle from obese and diabetic subjects. Am J Physiol Endocrinol Metab. 2012 Jul 01; 303(1):E82-9. Jensen J, Tantiwong P, Stuenæs JT, Molina-Carrion M, DeFronzo RA, Sakamoto K, Musi N. PMID: 22510711; PMCID: PMC3404561.
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    90. Does reduced IGF-1R signaling in Igf1r+/- mice alter aging? PLoS One. 2011; 6(11):e26891. Bokov AF, Garg N, Ikeno Y, Thakur S, Musi N, DeFronzo RA, Zhang N, Erickson RC, Gelfond J, Hubbard GB, Adamo ML, Richardson A. PMID: 22132081; PMCID: PMC3223158.
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    91. Potential role of insulin signaling on vascular smooth muscle cell migration, proliferation, and inflammation pathways. Am J Physiol Cell Physiol. 2012 Feb 15; 302(4):C652-7. Cersosimo E, Xu X, Musi N. PMID: 22094332.
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    92. Metabolic effects of muraglitazar in type 2 diabetic subjects. Diabetes Obes Metab. 2011 Oct; 13(10):893-902. Fernandez M, Gastaldelli A, Triplitt C, Hardies J, Casolaro A, Petz R, Tantiwong P, Musi N, Cersosimo E, Ferrannini E, DeFronzo RA. PMID: 21615671.
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    93. Improving treatment in Hispanic/Latino patients. Am J Med. 2011 Oct; 124(10 Suppl):S16-21. Cersosimo E, Musi N. PMID: 21939794.
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    94. APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathway. Mol Endocrinol. 2011 Oct; 25(10):1773-85. Deepa SS, Zhou L, Ryu J, Wang C, Mao X, Li C, Zhang N, Musi N, DeFronzo RA, Liu F, Dong LQ. PMID: 21835890; PMCID: PMC3182423.
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    95. Critical role of chemokine (C-C motif) receptor 2 (CCR2) in the KKAy + Apoe -/- mouse model of the metabolic syndrome. Diabetologia. 2011 Oct; 54(10):2660-8. Martinez HG, Quinones MP, Jimenez F, Estrada CA, Clark K, Muscogiuri G, Sorice G, Musi N, Reddick RL, Ahuja SS. PMID: 21779871; PMCID: PMC4430553.
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    96. Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance. Diabetes. 2011 Aug; 60(8):2051-60. Ghosh S, Lertwattanarak R, Lefort N, Molina-Carrion M, Joya-Galeana J, Bowen BP, Garduno-Garcia Jde J, Abdul-Ghani M, Richardson A, DeFronzo RA, Mandarino L, Van Remmen H, Musi N. PMID: 21677280; PMCID: PMC3142073.
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    97. Effects of insulin and oral anti-diabetic agents on glucose metabolism, vascular dysfunction and skeletal muscle inflammation in type 2 diabetic subjects. Diabetes Metab Res Rev. 2011 May; 27(4):373-82. Joya-Galeana J, Fernandez M, Cervera A, Reyna S, Ghosh S, Triplitt C, Musi N, DeFronzo RA, Cersosimo E. PMID: 21309063; PMCID: PMC4416699.
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    98. β-Adrenergic Responsive Induction of Insulin Resistance in Liver of Aging Rats. Endocr Res. 2011; 36(2):74-82. Muscogiuri G, Kamat A, Balas B, Giaccari A, Defronzo RA, Musi N, Katz MS. PMID: 21438725.
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    99. Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med. 2011 Mar 24; 364(12):1104-15. DeFronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Henry RR, Hodis HN, Kitabchi AE, Mack WJ, Mudaliar S, Ratner RE, Williams K, Stentz FB, Musi N, Reaven PD, ACT NOW Study. PMID: 21428766.
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    100. Effect of exenatide on splanchnic and peripheral glucose metabolism in type 2 diabetic subjects. J Clin Endocrinol Metab. 2011 Jun; 96(6):1763-70. Cersosimo E, Gastaldelli A, Cervera A, Wajcberg E, Sriwijilkamol A, Fernandez M, Zuo P, Petz R, Triplitt C, Musi N, DeFronzo RA. PMID: 21411546.
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    101. NF-κB activity in muscle from obese and type 2 diabetic subjects under basal and exercise-stimulated conditions. Am J Physiol Endocrinol Metab. 2010 Nov; 299(5):E794-801. Tantiwong P, Shanmugasundaram K, Monroy A, Ghosh S, Li M, DeFronzo RA, Cersosimo E, Sriwijitkamol A, Mohan S, Musi N. PMID: 20739506; PMCID: PMC2980364.
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    102. The ontogeny of insulin signaling in the preterm baboon model. Endocrinology. 2010 May; 151(5):1990-7. Blanco CL, Liang H, Joya-Galeana J, DeFronzo RA, McCurnin D, Musi N. PMID: 20233798; PMCID: PMC2869258.
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    103. Effects of pioglitazone on intramyocellular fat metabolism in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab. 2010 Apr; 95(4):1916-23. Bajaj M, Baig R, Suraamornkul S, Hardies LJ, Coletta DK, Cline GW, Monroy A, Koul S, Sriwijitkamol A, Musi N, Shulman GI, DeFronzo RA. PMID: 20157197; PMCID: PMC2853997.
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    104. Determinants of glucose tolerance in impaired glucose tolerance at baseline in the Actos Now for Prevention of Diabetes (ACT NOW) study. Diabetologia. 2010 Mar; 53(3):435-45. DeFronzo RA, Banerji MA, Bray GA, Buchanan TA, Clement S, Henry RR, Kitabchi AE, Mudaliar S, Musi N, Ratner R, Reaven P, Schwenke DC, Stentz FD, Tripathy D, ACT NOW Study Group. PMID: 20012012.
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    105. Actos Now for the prevention of diabetes (ACT NOW) study. BMC Endocr Disord. 2009 Jul 29; 9:17. Defronzo RA, Banerji M, Bray GA, Buchanan TA, Clement S, Henry RR, Kitabchi AE, Mudaliar S, Musi N, Ratner R, Reaven PD, Schwenke D, Stentz FB, Tripathy D. PMID: 19640291; PMCID: PMC2725044.
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    106. Impaired regulation of the TNF-alpha converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: a new mechanism of insulin resistance in humans. Diabetologia. 2009 Oct; 52(10):2169-81. Monroy A, Kamath S, Chavez AO, Centonze VE, Veerasamy M, Barrentine A, Wewer JJ, Coletta DK, Jenkinson C, Jhingan RM, Smokler D, Reyna S, Musi N, Khokka R, Federici M, Tripathy D, DeFronzo RA, Folli F. PMID: 19633828; PMCID: PMC2845986.
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    107. IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. Mol Endocrinol. 2009 May; 23(5):662-70. Ghosh S, Choudary A, Ghosh S, Musi N, Hu Y, Li R. PMID: 19221050; PMCID: PMC2675949.
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    108. Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity. Am J Physiol Endocrinol Metab. 2009 Apr; 296(4):E945-54. Liang H, Balas B, Tantiwong P, Dube J, Goodpaster BH, O'Doherty RM, DeFronzo RA, Richardson A, Musi N, Ward WF. PMID: 19208857; PMCID: PMC2670619.
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    109. Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial. Diabetologia. 2009 Apr; 52(4):723-32. Coletta DK, Sriwijitkamol A, Wajcberg E, Tantiwong P, Li M, Prentki M, Madiraju M, Jenkinson CP, Cersosimo E, Musi N, Defronzo RA. PMID: 19169664; PMCID: PMC4894502.
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    110. Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators. IUBMB Life. 2009 Jan; 61(1):18-26. Guigas B, Sakamoto K, Taleux N, Reyna SM, Musi N, Viollet B, Hue L. PMID: 18798311; PMCID: PMC2845387.
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    111. Advances in the development of AMPK-activating compounds. Expert Opin Drug Discov. 2008 Oct; 3(10):1167-76. Sriwijitkamol A, Musi N. PMID: 23489075.
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    113. Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects. Diabetes. 2008 Oct; 57(10):2595-602. Reyna SM, Ghosh S, Tantiwong P, Meka CS, Eagan P, Jenkinson CP, Cersosimo E, Defronzo RA, Coletta DK, Sriwijitkamol A, Musi N. PMID: 18633101; PMCID: PMC2551667.
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    114. Diabetic eNOS knockout mice develop distinct macro- and microvascular complications. Lab Invest. 2008 May; 88(5):515-28. Mohan S, Reddick RL, Musi N, Horn DA, Yan B, Prihoda TJ, Natarajan M, Abboud-Werner SL. PMID: 18391994.
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    115. Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes. Am J Physiol Endocrinol Metab. 2008 May; 294(5):E846-52. Cervera A, Wajcberg E, Sriwijitkamol A, Fernandez M, Zuo P, Triplitt C, Musi N, DeFronzo RA, Cersosimo E. PMID: 18334612.
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    116. Physiological and molecular determinants of insulin action in the baboon. Diabetes. 2008 Apr; 57(4):899-908. Chavez AO, Lopez-Alvarenga JC, Tejero ME, Triplitt C, Bastarrachea RA, Sriwijitkamol A, Tantiwong P, Voruganti VS, Musi N, Comuzzie AG, DeFronzo RA, Folli F. PMID: 18174524.
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    117. Peripheral disruption of the Grb10 gene enhances insulin signaling and sensitivity in vivo. Mol Cell Biol. 2007 Sep; 27(18):6497-505. Wang L, Balas B, Christ-Roberts CY, Kim RY, Ramos FJ, Kikani CK, Li C, Deng C, Reyna S, Musi N, Dong LQ, DeFronzo RA, Liu F. PMID: 17620412; PMCID: PMC2099625.
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    118. Effects of peroxisome proliferator-activated receptor (PPAR)-alpha and PPAR-gamma agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus. Diabetologia. 2007 Aug; 50(8):1723-31. Bajaj M, Suraamornkul S, Hardies LJ, Glass L, Musi N, DeFronzo RA. PMID: 17520238.
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    119. Palmitic acid induces IP-10 expression in human macrophages via NF-kappaB activation. Biochem Biophys Res Commun. 2007 Jun 22; 358(1):150-5. Laine PS, Schwartz EA, Wang Y, Zhang WY, Karnik SK, Musi N, Reaven PD. PMID: 17467667.
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    120. Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest. 2007 May; 117(5):1432-9. Luptak I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita H, Arad M, Seidman CE, Seidman JG, Ingwall JS, Balschi JA, Tian R. PMID: 17431505; PMCID: PMC1847536.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    121. Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study. Diabetes. 2007 Mar; 56(3):836-48. Sriwijitkamol A, Coletta DK, Wajcberg E, Balbontin GB, Reyna SM, Barrientes J, Eagan PA, Jenkinson CP, Cersosimo E, DeFronzo RA, Sakamoto K, Musi N. PMID: 17327455; PMCID: PMC2844111.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansCellsCTClinical Trials
    122. Relationship between vascular reactivity and lipids in Mexican-Americans with type 2 diabetes treated with pioglitazone. J Clin Endocrinol Metab. 2007 Apr; 92(4):1256-62. Wajcberg E, Sriwijitkamol A, Musi N, DeFronzo RA, Cersosimo E. PMID: 17244785.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    123. AMP-activated protein kinase: Role in metabolism and therapeutic implications. Diabetes Obes Metab. 2006 Nov; 8(6):591-602. Schimmack G, Defronzo RA, Musi N. PMID: 17026483.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    124. A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy. Am J Physiol Renal Physiol. 2007 Feb; 292(2):F617-27. Lee MJ, Feliers D, Mariappan MM, Sataranatarajan K, Mahimainathan L, Musi N, Foretz M, Viollet B, Weinberg JM, Choudhury GG, Kasinath BS. PMID: 17018841.
      View in: PubMed   Mentions: 145     Fields:    Translation:AnimalsCells
    125. Reduced skeletal muscle inhibitor of kappaB beta content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise training. Diabetes. 2006 Mar; 55(3):760-7. Sriwijitkamol A, Christ-Roberts C, Berria R, Eagan P, Pratipanawatr T, DeFronzo RA, Mandarino LJ, Musi N. PMID: 16505240.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    126. Insulin resistance and improvements in signal transduction. Endocrine. 2006 Feb; 29(1):73-80. Musi N, Goodyear LJ. PMID: 16622294.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    127. Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle. Am J Physiol Endocrinol Metab. 2006 Jun; 290(6):E1296-303. Kuhl JE, Ruderman NB, Musi N, Goodyear LJ, Patti ME, Crunkhorn S, Dronamraju D, Thorell A, Nygren J, Ljungkvist O, Degerblad M, Stahle A, Brismar TB, Andersen KL, Saha AK, Efendic S, Bavenholm PN. PMID: 16434556.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCellsCTClinical Trials
    128. AMP-activated protein kinase and type 2 diabetes. Curr Med Chem. 2006; 13(5):583-9. Musi N. PMID: 16515522.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    129. LKB1-AMPK signaling in muscle from obese insulin-resistant Zucker rats and effects of training. Am J Physiol Endocrinol Metab. 2006 May; 290(5):E925-32. Sriwijitkamol A, Ivy JL, Christ-Roberts C, DeFronzo RA, Mandarino LJ, Musi N. PMID: 16352671.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    130. Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy. Circulation. 2005 Nov 15; 112(20):3140-8. Ahmad F, Arad M, Musi N, He H, Wolf C, Branco D, Perez-Atayde AR, Stapleton D, Bali D, Xing Y, Tian R, Goodyear LJ, Berul CI, Ingwall JS, Seidman CE, Seidman JG. PMID: 16275868.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    131. Functional role of AMP-activated protein kinase in the heart during exercise. FEBS Lett. 2005 Apr 11; 579(10):2045-50. Musi N, Hirshman MF, Arad M, Xing Y, Fujii N, Pomerleau J, Ahmad F, Berul CI, Seidman JG, Tian R, Goodyear LJ. PMID: 15811316.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    132. Regulation of glucose transport by the AMP-activated protein kinase. Proc Nutr Soc. 2004 May; 63(2):205-10. Fujii N, Aschenbach WG, Musi N, Hirshman MF, Goodyear LJ. PMID: 15294031.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    133. AMP-activated protein kinase and muscle glucose uptake. Acta Physiol Scand. 2003 Aug; 178(4):337-45. Musi N, Goodyear LJ. PMID: 12864738.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    134. Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative alpha2 subunit of AMP-activated protein kinase. J Biol Chem. 2003 Aug 01; 278(31):28372-7. Xing Y, Musi N, Fujii N, Zou L, Luptak I, Hirshman MF, Goodyear LJ, Tian R. PMID: 12766162.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    135. AMP-activated protein kinase regulation and action in skeletal muscle during exercise. Biochem Soc Trans. 2003 Feb; 31(Pt 1):191-5. Musi N, Yu H, Goodyear LJ. PMID: 12546683.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    136. Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes. 2002 Jul; 51(7):2074-81. Musi N, Hirshman MF, Nygren J, Svanfeldt M, Bavenholm P, Rooyackers O, Zhou G, Williamson JM, Ljunqvist O, Efendic S, Moller DE, Thorell A, Goodyear LJ. PMID: 12086935.
      View in: PubMed   Mentions: 265     Fields:    Translation:HumansCTClinical Trials
    137. Targeting the AMP-activated protein kinase for the treatment of type 2 diabetes. Curr Drug Targets Immune Endocr Metabol Disord. 2002 Jul; 2(2):119-27. Musi N, Goodyear LJ. PMID: 12476786.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    138. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest. 2001 Oct; 108(8):1167-74. Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE. PMID: 11602624; PMCID: PMC209533.
      View in: PubMed   Mentions: 2142     Fields:    Translation:HumansAnimalsCells
    139. AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle. Am J Physiol Endocrinol Metab. 2001 May; 280(5):E677-84. Musi N, Hayashi T, Fujii N, Hirshman MF, Witters LA, Goodyear LJ. PMID: 11287349.
      View in: PubMed   Mentions: 73     Fields:    Translation:Animals
    140. AMP-activated protein kinase (AMPK) is activated in muscle of subjects with type 2 diabetes during exercise. Diabetes. 2001 May; 50(5):921-7. Musi N, Fujii N, Hirshman MF, Ekberg I, Fröberg S, Ljungqvist O, Thorell A, Goodyear LJ. PMID: 11334434.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansCells
    141. Severe thyrotoxicosis after parathyroid surgery for hyperparathyroidism. Am J Med. 2000 Apr 15; 108(6):519-20. Musi N, Braverman LE, Norris CM. PMID: 10866589.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    142. [Comparative study of the digestive antecedents, localization and survival in 100 cases of verified gastric cancer: contribution to the problem of cancerous degeneration of gastric ulcer]. Acta Gastroenterol Belg. 1959 May; 22:306-14. MUSI N. PMID: 14425506.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    143. [Present state of our knowledge of poliomyelitis]. Clin Lab (Zaragoza). 1951 Oct; 52(307):299-306. INVALDI A, MARIN F, RAZETTA E, ESMENDI R, TORRESETTI E, BERTUCCI R, MUSI N, ZAGO T. PMID: 14896490.
      View in: PubMed   Mentions: Translation:Humans
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