Loading...

Hevener, Andrea L

Title(s)Professor-in-Residence, Medicine
SchoolEndocrinology
Phone75884
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms controlling skeletal muscle mitochondrial function and metabolic health
    NIH/NIDDK R01DK109724Apr 15, 2016 - Mar 31, 2021
    Role: Principal Investigator
    ERalpha and the metabolic syndrome
    NIH/NIDDK R01DK089109Aug 15, 2011 - Jun 30, 2015
    Role: Principal Investigator
    The Impact of Heat Shock Protein Expression on Inflammation and Insulin Action
    NIH/NIDDK R01DK078760Jul 15, 2009 - Jun 30, 2010
    Role: Principal Investigator
    The impact of PPAR-gamma and estrogen receptor crosstalk on insulin action
    NIH/NIDDK R21DK073227Sep 30, 2006 - Aug 31, 2009
    Role: Principal Investigator
    The Role of PPAR-gamma Expression on Insulin Action
    NIH/NIDDK K01DK060484Feb 15, 2002 - Jan 31, 2007
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Hevener AL, Ribas V, Moore TM, Zhou Z. The Impact of Skeletal Muscle ERa on Mitochondrial Function and Metabolic Health. Endocrinology. 2020 Feb 01; 161(2). PMID: 32053721.
      View in: PubMed
    2. Moore TM, Zhou Z, Cohn W, Norheim F, Lin AJ, Kalajian N, Strumwasser AR, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Shirihai O, van der Bliek AM, Whitelegge JP, Seldin MM, Lusis AJ, Lee S, Drevon CA, Mahata SK, Turcotte LP, Hevener AL. The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle. Mol Metab. 2019 03; 21:51-67. PMID: 30591411.
      View in: PubMed
    3. Bond ST, Moody SC, Liu Y, Civelek M, Villanueva CJ, Gregorevic P, Kingwell BA, Hevener AL, Lusis AJ, Henstridge DC, Calkin AC, Drew BG. The E3 ligase MARCH5 is a PPAR? target gene that regulates mitochondria and metabolism in adipocytes. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E293-E304. PMID: 30512991.
      View in: PubMed
    4. Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin XJ, Wong J, Ding S, Seki E, Schnabl B, Hevener AL, Greenberg HB, Kisseleva T, Karin M. New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. Nature. 2018 08; 560(7717):198-203. PMID: 30046112.
      View in: PubMed
    5. Hevener AL, Zhou Z, Moore TM, Drew BG, Ribas V. The impact of ERa action on muscle metabolism and insulin sensitivity - Strong enough for a man, made for a woman. Mol Metab. 2018 09; 15:20-34. PMID: 30005878.
      View in: PubMed
    6. Norheim F, Bjellaas T, Hui ST, Chella Krishnan K, Lee J, Gupta S, Pan C, Hasin-Brumshtein Y, Parks BW, Li DY, Bui HH, Mosier M, Wu Y, Huertas-Vazquez A, Hazen SL, Gundersen TE, Mehrabian M, Tang WHW, Hevener AL, Drevon CA, Lusis AJ. Genetic, dietary, and sex-specific regulation of hepatic ceramides and the relationship between hepatic ceramides and IR. J Lipid Res. 2018 07; 59(7):1164-1174. PMID: 29739864.
      View in: PubMed
    7. Zhou Z, Ribas V, Rajbhandari P, Drew BG, Moore TM, Fluitt AH, Reddish BR, Whitney KA, Georgia S, Vergnes L, Reue K, Liesa M, Shirihai O, van der Bliek AM, Chi NW, Mahata SK, Tiano JP, Hewitt SC, Tontonoz P, Korach KS, Mauvais-Jarvis F, Hevener AL. Estrogen receptor a protects pancreatic ß-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress. J Biol Chem. 2018 03 30; 293(13):4735-4751. PMID: 29378845.
      View in: PubMed
    8. Herbst A, Widjaja K, Nguy B, Lushaj EB, Moore TM, Hevener AL, McKenzie D, Aiken JM, Wanagat J. Digital PCR Quantitation of Muscle Mitochondrial DNA: Age, Fiber Type, and Mutation-Induced Changes. J Gerontol A Biol Sci Med Sci. 2017 Oct 01; 72(10):1327-1333. PMID: 28460005.
      View in: PubMed
    9. Song Y, Cho M, Brennan KM, Chen BH, Song Y, Manson JE, Hevener AL, You NY, Butch AW, Liu S. Relationships of sex hormone levels with leukocyte telomere length in Black, Hispanic, and Asian/Pacific Islander postmenopausal women. J Diabetes. 2018 Jun; 10(6):502-511. PMID: 28609023.
      View in: PubMed
    10. Clegg D, Hevener AL, Moreau KL, Morselli E, Criollo A, Van Pelt RE, Vieira-Potter VJ. Sex Hormones and Cardiometabolic Health: Role of Estrogen and Estrogen Receptors. Endocrinology. 2017 05 01; 158(5):1095-1105. PMID: 28323912.
      View in: PubMed
    11. Hevener AL, Zhou Z, Drew BG, Ribas V. The Role of Skeletal Muscle Estrogen Receptors in Metabolic Homeostasis and Insulin Sensitivity. Adv Exp Med Biol. 2017; 1043:257-284. PMID: 29224099.
      View in: PubMed
    12. McCurdy CE, Schenk S, Hetrick B, Houck J, Drew BG, Kaye S, Lashbrook M, Bergman BC, Takahashi DL, Dean TA, Nemkov T, Gertsman I, Hansen KC, Philp A, Hevener AL, Chicco AJ, Aagaard KM, Grove KL, Friedman JE. Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques. JCI Insight. 2016 Oct 06; 1(16):e86612. PMID: 27734025.
      View in: PubMed
    13. Wanagat J, Hevener AL. Mitochondrial quality control in insulin resistance and diabetes. Curr Opin Genet Dev. 2016 06; 38:118-126. PMID: 27318536.
      View in: PubMed
    14. Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. Skeletal muscle action of estrogen receptor a is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Sci Transl Med. 2016 Apr 13; 8(334):334ra54. PMID: 27075628.
      View in: PubMed
    15. Kramerova I, Ermolova N, Eskin A, Hevener A, Quehenberger O, Armando AM, Haller R, Romain N, Nelson SF, Spencer MJ. Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy). Hum Mol Genet. 2016 06 01; 25(11):2194-2207. PMID: 27005420.
      View in: PubMed
    16. Ashcroft F, Pearce E, Partridge L, Suomalainen A, Brunet A, Schulze A, Tseng YH, Sethi JK, Reue K, Kingwell B, McNally E, Cnop M, Hevener AL, Diano S. Women in Metabolism: Part 3. Cell Metab. 2015 Dec 01; 22(6):949-53. PMID: 26636490.
      View in: PubMed
    17. Pfluger PT, Kabra DG, Aichler M, Schriever SC, Pfuhlmann K, García VC, Lehti M, Weber J, Kutschke M, Rozman J, Elrod JW, Hevener AL, Feuchtinger A, Hrabe de Angelis M, Walch A, Rollmann SM, Aronow BJ, Müller TD, Perez-Tilve D, Jastroch M, De Luca M, Molkentin JD, Tschöp MH. Calcineurin Links Mitochondrial Elongation with Energy Metabolism. Cell Metab. 2015 Nov 03; 22(5):838-50. PMID: 26411342.
      View in: PubMed
    18. Roberts CK, Lee MM, Katiraie M, Krell SL, Angadi SS, Chronley MK, Oh CS, Ribas V, Harris RA, Hevener AL, Croymans DM. Strength fitness and body weight status on markers of cardiometabolic health. Med Sci Sports Exerc. 2015 Jun; 47(6):1211-8. PMID: 25251047.
      View in: PubMed
    19. Hevener AL, Clegg DJ, Mauvais-Jarvis F. Impaired estrogen receptor action in the pathogenesis of the metabolic syndrome. Mol Cell Endocrinol. 2015 Dec 15; 418 Pt 3:306-21. PMID: 26033249.
      View in: PubMed
    20. Lee C, Zeng J, Drew BG, Sallam T, Martin-Montalvo A, Wan J, Kim SJ, Mehta H, Hevener AL, de Cabo R, Cohen P. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 2015 Mar 03; 21(3):443-54. PMID: 25738459.
      View in: PubMed
    21. Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ. Genetic architecture of insulin resistance in the mouse. Cell Metab. 2015 Feb 03; 21(2):334-347. PMID: 25651185.
      View in: PubMed
    22. Song Y, Huang YT, Song Y, Hevener AL, Ryckman KK, Qi L, LeBlanc ES, Kazlauskaite R, Brennan KM, Liu S. Birthweight, mediating biomarkers and the development of type 2 diabetes later in life: a prospective study of multi-ethnic women. Diabetologia. 2015 Jun; 58(6):1220-30. PMID: 25567102.
      View in: PubMed
    23. Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL. Estrogen receptor (ER)a-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression. J Biol Chem. 2015 Feb 27; 290(9):5566-81. PMID: 25468909.
      View in: PubMed
    24. Henstridge DC, Bruce CR, Drew BG, Tory K, Kolonics A, Estevez E, Chung J, Watson N, Gardner T, Lee-Young RS, Connor T, Watt MJ, Carpenter K, Hargreaves M, McGee SL, Hevener AL, Febbraio MA. Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistance. Diabetes. 2014 Jun; 63(6):1881-94. PMID: 24430435.
      View in: PubMed
    25. Kim JH, Meyers MS, Khuder SS, Abdallah SL, Muturi HT, Russo L, Tate CR, Hevener AL, Najjar SM, Leloup C, Mauvais-Jarvis F. Tissue-selective estrogen complexes with bazedoxifene prevent metabolic dysfunction in female mice. Mol Metab. 2014 Apr; 3(2):177-90. PMID: 24634829.
      View in: PubMed
    26. Drew BG, Ribas V, Le JA, Henstridge DC, Phun J, Zhou Z, Soleymani T, Daraei P, Sitz D, Vergnes L, Wanagat J, Reue K, Febbraio MA, Hevener AL. HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle. Diabetes. 2014 May; 63(5):1488-505. PMID: 24379352.
      View in: PubMed
    27. Beaven SW, Matveyenko A, Wroblewski K, Chao L, Wilpitz D, Hsu TW, Lentz J, Drew B, Hevener AL, Tontonoz P. Reciprocal regulation of hepatic and adipose lipogenesis by liver X receptors in obesity and insulin resistance. Cell Metab. 2013 Jul 02; 18(1):106-17. PMID: 23823481.
      View in: PubMed
    28. Wend K, Wend P, Drew BG, Hevener AL, Miranda-Carboni GA, Krum SA. ERa regulates lipid metabolism in bone through ATGL and perilipin. J Cell Biochem. 2013 Jun; 114(6):1306-14. PMID: 23296636.
      View in: PubMed
    29. Villanueva CJ, Vergnes L, Wang J, Drew BG, Hong C, Tu Y, Hu Y, Peng X, Xu F, Saez E, Wroblewski K, Hevener AL, Reue K, Fong LG, Young SG, Tontonoz P. Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPAR? specifies lipid storage versus thermogenic gene programs. Cell Metab. 2013 Mar 05; 17(3):423-35. PMID: 23473036.
      View in: PubMed
    30. Mauvais-Jarvis F, Clegg DJ, Hevener AL. The role of estrogens in control of energy balance and glucose homeostasis. Endocr Rev. 2013 Jun; 34(3):309-38. PMID: 23460719.
      View in: PubMed
    31. Roberts CK, Hevener AL, Barnard RJ. Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training. Compr Physiol. 2013 Jan; 3(1):1-58. PMID: 23720280.
      View in: PubMed
    32. Chao LC, Wroblewski K, Ilkayeva OR, Stevens RD, Bain J, Meyer GA, Schenk S, Martinez L, Vergnes L, Narkar VA, Drew BG, Hong C, Boyadjian R, Hevener AL, Evans RM, Reue K, Spencer MJ, Newgard CB, Tontonoz P. Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. J Lipid Res. 2012 Dec; 53(12):2610-9. PMID: 23028113.
      View in: PubMed
    33. Gombos I, Crul T, Piotto S, Güngör B, Török Z, Balogh G, Péter M, Slotte JP, Campana F, Pilbat AM, Hunya A, Tóth N, Literati-Nagy Z, Vígh L, Glatz A, Brameshuber M, Schütz GJ, Hevener A, Febbraio MA, Horváth I, Vígh L. Membrane-lipid therapy in operation: the HSP co-inducer BGP-15 activates stress signal transduction pathways by remodeling plasma membrane rafts. PLoS One. 2011; 6(12):e28818. PMID: 22174906.
      View in: PubMed
    34. Ribas V, Drew BG, Le JA, Soleymani T, Daraei P, Sitz D, Mohammad L, Henstridge DC, Febbraio MA, Hewitt SC, Korach KS, Bensinger SJ, Hevener AL. Myeloid-specific estrogen receptor alpha deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development. Proc Natl Acad Sci U S A. 2011 Sep 27; 108(39):16457-62. PMID: 21900603.
      View in: PubMed
    35. Monetti M, Levin MC, Watt MJ, Hubbard BK, Newgard C, Farese RV, Hevener AL, Farese RV. Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity. Proc Natl Acad Sci U S A. 2011 Aug 23; 108(34):E523; author reply E524. PMID: 21807991.
      View in: PubMed
    36. Villanueva CJ, Waki H, Godio C, Nielsen R, Chou WL, Vargas L, Wroblewski K, Schmedt C, Chao LC, Boyadjian R, Mandrup S, Hevener A, Saez E, Tontonoz P. TLE3 is a dual-function transcriptional coregulator of adipogenesis. Cell Metab. 2011 Apr 06; 13(4):413-427. PMID: 21459326.
      View in: PubMed
    37. Sachithanandan N, Fam BC, Fynch S, Dzamko N, Watt MJ, Wormald S, Honeyman J, Galic S, Proietto J, Andrikopoulos S, Hevener AL, Kay TW, Steinberg GR. Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity. Hepatology. 2010 Nov; 52(5):1632-42. PMID: 20799351.
      View in: PubMed
    38. Yamada PM, Mehta HH, Hwang D, Roos KP, Hevener AL, Lee KW. Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation. Endocrinology. 2010 Dec; 151(12):5741-50. PMID: 20926583.
      View in: PubMed
    39. Hevener AL, Febbraio MA. The 2009 stock conference report: inflammation, obesity and metabolic disease. Obes Rev. 2010 Sep; 11(9):635-44. PMID: 20002885.
      View in: PubMed
    40. Srikanthan P, Hevener AL, Karlamangla AS. Sarcopenia exacerbates obesity-associated insulin resistance and dysglycemia: findings from the National Health and Nutrition Examination Survey III. PLoS One. 2010 May 26; 5(5):e10805. PMID: 22421977.
      View in: PubMed
    41. Ribas V, Nguyen MT, Henstridge DC, Nguyen AK, Beaven SW, Watt MJ, Hevener AL. Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERalpha-deficient mice. Am J Physiol Endocrinol Metab. 2010 Feb; 298(2):E304-19. PMID: 19920214.
      View in: PubMed
    42. Dzamko N, van Denderen BJ, Hevener AL, Jørgensen SB, Honeyman J, Galic S, Chen ZP, Watt MJ, Campbell DJ, Steinberg GR, Kemp BE. AMPK beta1 deletion reduces appetite, preventing obesity and hepatic insulin resistance. J Biol Chem. 2010 Jan 01; 285(1):115-22. PMID: 19892703.
      View in: PubMed
    43. Chao LC, Wroblewski K, Zhang Z, Pei L, Vergnes L, Ilkayeva OR, Ding SY, Reue K, Watt MJ, Newgard CB, Pilch PF, Hevener AL, Tontonoz P. Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. Diabetes. 2009 Dec; 58(12):2788-96. PMID: 19741162.
      View in: PubMed
    44. Yeh TY, Beiswenger KK, Li P, Bolin KE, Lee RM, Tsao TS, Murphy AN, Hevener AL, Chi NW. Hypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice. Diabetes. 2009 Nov; 58(11):2476-85. PMID: 19651815.
      View in: PubMed
    45. Crowe S, Wu LE, Economou C, Turpin SM, Matzaris M, Hoehn KL, Hevener AL, James DE, Duh EJ, Watt MJ. Pigment epithelium-derived factor contributes to insulin resistance in obesity. Cell Metab. 2009 Jul; 10(1):40-7. PMID: 19583952.
      View in: PubMed
    46. Turpin SM, Ryall JG, Southgate R, Darby I, Hevener AL, Febbraio MA, Kemp BE, Lynch GS, Watt MJ. Examination of 'lipotoxicity' in skeletal muscle of high-fat fed and ob/ob mice. J Physiol. 2009 Apr 01; 587(Pt 7):1593-605. PMID: 19204053.
      View in: PubMed
    47. Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA. HSP72 protects against obesity-induced insulin resistance. Proc Natl Acad Sci U S A. 2008 Feb 05; 105(5):1739-44. PMID: 18223156.
      View in: PubMed
    48. Watt MJ, Hevener AL. Fluxing the mitochondria to insulin resistance. Cell Metab. 2008 Jan; 7(1):5-6. PMID: 18177719.
      View in: PubMed
    49. Pascual G, Ricote M, Hevener AL. Macrophage peroxisome proliferator activated receptor gamma as a therapeutic target to combat Type 2 diabetes. Expert Opin Ther Targets. 2007 Nov; 11(11):1503-20. PMID: 18028013.
      View in: PubMed
    50. Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese RV, Hevener AL, Farese RV. Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. Cell Metab. 2007 Jul; 6(1):69-78. PMID: 17618857.
      View in: PubMed
    51. Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest. 2007 Jun; 117(6):1658-69. PMID: 17525798.
      View in: PubMed
    52. Todd MK, Watt MJ, Le J, Hevener AL, Turcotte LP. Thiazolidinediones enhance skeletal muscle triacylglycerol synthesis while protecting against fatty acid-induced inflammation and insulin resistance. Am J Physiol Endocrinol Metab. 2007 Feb; 292(2):E485-93. PMID: 17003244.
      View in: PubMed
    53. Lee CH, Olson P, Hevener A, Mehl I, Chong LW, Olefsky JM, Gonzalez FJ, Ham J, Kang H, Peters JM, Evans RM. PPARdelta regulates glucose metabolism and insulin sensitivity. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3444-9. PMID: 16492734.
      View in: PubMed
    54. Watt MJ, Hevener A, Lancaster GI, Febbraio MA. Ciliary neurotrophic factor prevents acute lipid-induced insulin resistance by attenuating ceramide accumulation and phosphorylation of c-Jun N-terminal kinase in peripheral tissues. Endocrinology. 2006 May; 147(5):2077-85. PMID: 16396984.
      View in: PubMed
    55. Bard-Chapeau EA, Hevener AL, Long S, Zhang EE, Olefsky JM, Feng GS. Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action. Nat Med. 2005 May; 11(5):567-71. PMID: 15821749.
      View in: PubMed
    56. Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M. IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med. 2005 Feb; 11(2):191-8. PMID: 15685170.
      View in: PubMed
    57. Wiedmer T, Zhao J, Li L, Zhou Q, Hevener A, Olefsky JM, Curtiss LK, Sims PJ. Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3). Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13296-301. PMID: 15328404.
      View in: PubMed
    58. Sumida KD, Garrett JH, McJilton WT, Hevener AL, Donovan CM. Effect of endurance training and fasting on renal gluconeogenic enzymes in the rat. Int J Sport Nutr Exerc Metab. 2004 Jun; 14(3):323-32. PMID: 15256692.
      View in: PubMed
    59. He W, Barak Y, Hevener A, Olson P, Liao D, Le J, Nelson M, Ong E, Olefsky JM, Evans RM. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15712-7. PMID: 14660788.
      View in: PubMed
    60. Hevener AL, He W, Barak Y, Le J, Bandyopadhyay G, Olson P, Wilkes J, Evans RM, Olefsky J. Muscle-specific Pparg deletion causes insulin resistance. Nat Med. 2003 Dec; 9(12):1491-7. PMID: 14625542.
      View in: PubMed
    61. Wilkes JJ, Hevener A, Olefsky J. Chronic endothelin-1 treatment leads to insulin resistance in vivo. Diabetes. 2003 Aug; 52(8):1904-9. PMID: 12882904.
      View in: PubMed
    62. Yu JG, Javorschi S, Hevener AL, Kruszynska YT, Norman RA, Sinha M, Olefsky JM. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes. 2002 Oct; 51(10):2968-74. PMID: 12351435.
      View in: PubMed
    63. Hevener A, Reichart D, Janez A, Olefsky J. Female rats do not exhibit free fatty acid-induced insulin resistance. Diabetes. 2002 Jun; 51(6):1907-12. PMID: 12031980.
      View in: PubMed
    64. Worrall DS, McDunn JE, List B, Reichart D, Hevener A, Gustafson T, Barbas CF, Lerner RA, Olefsky JM. Synthesis of an organoinsulin molecule that can be activated by antibody catalysis. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13514-8. PMID: 11707596.
      View in: PubMed
    65. Hevener AL, Reichart D, Janez A, Olefsky J. Thiazolidinedione treatment prevents free fatty acid-induced insulin resistance in male wistar rats. Diabetes. 2001 Oct; 50(10):2316-22. PMID: 11574414.
      View in: PubMed
    66. Hevener AL, Bergman RN, Donovan CM. Hypoglycemic detection does not occur in the hepatic artery or liver: findings consistent with a portal vein glucosensor locus. Diabetes. 2001 Feb; 50(2):399-403. PMID: 11272153.
      View in: PubMed
    67. Hevener AL, Reichart D, Olefsky J. Exercise and thiazolidinedione therapy normalize insulin action in the obese Zucker fatty rat. Diabetes. 2000 Dec; 49(12):2154-9. PMID: 11118020.
      View in: PubMed
    68. Hevener AL, Bergman RN, Donovan CM. Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes. 2000 Jan; 49(1):8-12. PMID: 10615943.
      View in: PubMed
    69. Hevener AL, Bergman RN, Donovan CM. Novel glucosensor for hypoglycemic detection localized to the portal vein. Diabetes. 1997 Sep; 46(9):1521-5. PMID: 9287058.
      View in: PubMed