Helen Sara Goodridge

Title(s)Adjunct Professor, Medicine
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Monocyte Production by Bone Marrow Progenitors
    NIH R01AI134987May 15, 2018 - Apr 30, 2023
    Role: Principal Investigator
    Effects of Microbial Exposure on Myelopoiesis
    NIH R21AI082379Sep 18, 2010 - Aug 31, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. NLRP3, NLRP6, and NLRP12 are inflammasomes with distinct expression patterns. Front Immunol. 2024; 15:1418290. Wei B, Billman ZP, Nozaki K, Goodridge HS, Miao EA. PMID: 39076995; PMCID: PMC11284034.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. MYCT1 controls environmental sensing in human haematopoietic stem cells. Nature. 2024 Jun; 630(8016):412-420. Aguadé-Gorgorió J, Jami-Alahmadi Y, Calvanese V, Kardouh M, Fares I, Johnson H, Rezek V, Ma F, Magnusson M, Wang Y, Shin JE, Nance KJ, Goodridge HS, Liebscher S, Schenke-Layland K, Crooks GM, Wohlschlegel JA, Mikkola HKA. PMID: 38839950; PMCID: PMC11168926.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Microglia undergo sex-dimorphic transcriptional and metabolic rewiring during aging. J Neuroinflammation. 2024 Jun 05; 21(1):150. Kang S, Ko EY, Andrews AE, Shin JE, Nance KJ, Barman PK, Heeger PS, Freeman WM, Benayoun BA, Goodridge HS. PMID: 38840206; PMCID: PMC11155174.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Progenitor diversity defines monocyte roles. Blood. 2023 08 17; 142(7):617-619. Goodridge HS. PMID: 37590027; PMCID: PMC10485370.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    5. Aging of classical monocyte subsets. Aging (Albany NY). 2023 01 16; 15(2):290-292. Goodridge HS. PMID: 36645917; PMCID: PMC9925684.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    6. Single-cell transcriptomic analysis of endometriosis. Nat Genet. 2023 02; 55(2):255-267. Fonseca MAS, Haro M, Wright KN, Lin X, Abbasi F, Sun J, Hernandez L, Orr NL, Hong J, Choi-Kuaea Y, Maluf HM, Balzer BL, Fishburn A, Hickey R, Cass I, Goodridge HS, Truong M, Wang Y, Pisarska MD, Dinh HQ, El-Naggar A, Huntsman DG, Anglesio MS, Goodman MT, Medeiros F, Siedhoff M, Lawrenson K. PMID: 36624343; PMCID: PMC10950360.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    7. circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment. Nat Commun. 2022 11 25; 13(1):7243. Piras R, Ko EY, Barrett C, De Simone M, Lin X, Broz MT, Tessaro FHG, Castillo-Martin M, Cordon-Cardo C, Goodridge HS, Di Vizio D, Batish M, Lawrenson K, Chen YG, Chan KS, Guarnerio J. PMID: 36433954; PMCID: PMC9700836.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    8. Evidence of premature lymphocyte aging in people with low anti-spike antibody levels after BNT162b2 vaccination. iScience. 2022 Oct 21; 25(10):105209. Huang Y, Shin JE, Xu AM, Yao C, Joung S, Wu M, Zhang R, Shin B, Foley J, Mahov SB, Modes ME, Ebinger JE, Driver M, Braun JG, Jefferies CA, Parimon T, Hayes C, Sobhani K, Merchant A, Gharib SA, Jordan SC, Cheng S, Goodridge HS, Chen P. PMID: 36188190; PMCID: PMC9510055.
      View in: PubMed   Mentions: 2  
    9. Production of MHCII-expressing classical monocytes increases during aging in mice and humans. Aging Cell. 2022 10; 21(10):e13701. Barman PK, Shin JE, Lewis SA, Kang S, Wu D, Wang Y, Yang X, Nagarkatti PS, Nagarkatti M, Messaoudi I, Benayoun BA, Goodridge HS. PMID: 36040389; PMCID: PMC9577948.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    10. BATF3 Protects Against Metabolic Syndrome and Maintains Intestinal Epithelial Homeostasis. Front Immunol. 2022; 13:841065. Hamade H, Stamps JT, Stamps DT, More SK, Thomas LS, Blackwood AY, Lahcene NL, Castanon SL, Salumbides BC, Shimodaira Y, Goodridge HS, Targan SR, Michelsen KS. PMID: 35812447; PMCID: PMC9257242.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    11. Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity. Cell Rep. 2022 06 21; 39(12):110977. Tessaro FHG, Ko EY, De Simone M, Piras R, Broz MT, Goodridge HS, Balzer B, Shiao SL, Guarnerio J. PMID: 35732118; PMCID: PMC9249098.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    12. Demographic and clinical characteristics associated with variations in antibody response to BNT162b2 COVID-19 vaccination among healthcare workers at an academic medical centre: a longitudinal cohort analysis. BMJ Open. 2022 05 24; 12(5):e059994. Ebinger JE, Joung S, Liu Y, Wu M, Weber B, Claggett B, Botting PG, Sun N, Driver M, Kao YH, Khuu B, Wynter T, Nguyen TT, Alotaibi M, Prostko JC, Frias EC, Stewart JL, Goodridge HS, Chen P, Jordan SC, Jain M, Sharma S, Fert-Bober J, Van Eyk JE, Minissian MB, Arditi M, Melmed GY, Braun JG, McGovern DPB, Cheng S, Sobhani K. PMID: 35613792; PMCID: PMC9130668.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsPHPublic Health
    13. Neutrophil phenotypes and functions in cancer: A consensus statement. J Exp Med. 2022 06 06; 219(6). Quail DF, Amulic B, Aziz M, Barnes BJ, Eruslanov E, Fridlender ZG, Goodridge HS, Granot Z, Hidalgo A, Huttenlocher A, Kaplan MJ, Malanchi I, Merghoub T, Meylan E, Mittal V, Pittet MJ, Rubio-Ponce A, Udalova IA, van den Berg TK, Wagner DD, Wang P, Zychlinsky A, de Visser KE, Egeblad M, Kubes P. PMID: 35522219; PMCID: PMC9086501.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    14. Heterogeneity and origins of myeloid cells. Curr Opin Hematol. 2022 07 01; 29(4):201-208. Yáñez A, Bono C, Goodridge HS. PMID: 35285448; PMCID: PMC9256773.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    15. Microbial Sensing by Hematopoietic Stem and Progenitor Cells. Stem Cells. 2022 03 03; 40(1):14-21. Barman PK, Goodridge HS. PMID: 35511863; PMCID: PMC9072977.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    16. COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver. Cell Rep. 2021 11 16; 37(7):110026. Cohen K, Mouhadeb O, Ben Shlomo S, Langer M, Neumann A, Erez N, Moshkovits I, Pelet R, Kedar DJ, Brazowski E, Guilliams M, Goodridge HS, Gluck N, Varol C. PMID: 34788631; PMCID: PMC8998879.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    17. Sample processing and single cell RNA-sequencing of peripheral blood immune cells from COVID-19 patients. STAR Protoc. 2021 06 18; 2(2):100582. Yao C, Bora SA, Chen P, Goodridge HS, Gharib SA. PMID: 34002169; PMCID: PMC8114807.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    18. Cell-type-specific immune dysregulation in severely ill COVID-19 patients. Cell Rep. 2021 Mar 30; 34(13):108943. Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Surapaneni NS, Matusov YP, Chiang GC, Kassar AG, Patel N, Green CER, Aziz AW, Suri H, Suda J, Lopez AA, Martins GA, Stripp BR, Gharib SA, Goodridge HS, Chen P. PMID: 33789116; PMCID: PMC8009498.
      View in: PubMed   Mentions: 12     Fields:    
    19. Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients. Cell Rep. 2021 01 05; 34(1):108590. Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Surapaneni NS, Matusov YP, Cerro Chiang G, Kassar AG, Patel N, Green CER, Aziz AW, Suri H, Suda J, Lopez AA, Martins GA, Stripp BR, Gharib SA, Goodridge HS, Chen P. PMID: 33357411; PMCID: PMC7744012.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    20. Cell type-specific immune dysregulation in severely ill COVID-19 patients. medRxiv. 2020 Jul 24. Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Surapaneni NS, Matusov YP, Chiang GC, Kassar AG, Patel N, Green CE, Aziz AW, Suri H, Suda J, Lopez AA, Martins GA, Stripp BR, Gharib SA, Goodridge HS, Chen P. PMID: 32743611; PMCID: PMC7386732.
      View in: PubMed   Mentions:
    21. TLR2 and Dectin-1 Signaling in Mouse Hematopoietic Stem and Progenitor Cells Impacts the Ability of the Antigen Presenting Cells They Produce to Activate CD4 T Cells. Cells. 2020 05 25; 9(5). Martínez A, Bono C, Gozalbo D, Goodridge HS, Gil ML, Yáñez A. PMID: 32466296; PMCID: PMC7290964.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    22. Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls. iScience. 2020 Jun 26; 23(6):101192. Zhao W, Beers DR, Thonhoff JR, Thome AD, Faridar A, Wang J, Wen S, Ornelas L, Sareen D, Goodridge HS, Svendsen CN, Appel SH. PMID: 32521508; PMCID: PMC7286967.
      View in: PubMed   Mentions: 18  
    23. Rejuvenating the blood and bone marrow to slow aging-associated cognitive decline and Alzheimer's disease. Commun Biol. 2020 02 13; 3(1):69. Kang S, Moser VA, Svendsen CN, Goodridge HS. PMID: 32054965; PMCID: PMC7018752.
      View in: PubMed   Mentions: 8  Translation:HumansAnimals
    24. The Ontogeny of Monocyte Subsets. Front Immunol. 2019; 10:1642. Wolf AA, Yáñez A, Barman PK, Goodridge HS. PMID: 31379841; PMCID: PMC6650567.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    25. Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans. Obesity (Silver Spring). 2019 03; 27(3):434-443. Ehrhardt N, Cui J, Dagdeviren S, Saengnipanthkul S, Goodridge HS, Kim JK, Lantier L, Guo X, Chen YI, Raffel LJ, Buchanan TA, Hsueh WA, Rotter JI, Goodarzi MO, Péterfy M. PMID: 30801985; PMCID: PMC6474357.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    26. Young bone marrow transplantation preserves learning and memory in old mice. Commun Biol. 2019; 2:73. Das MM, Godoy M, Chen S, Moser VA, Avalos P, Roxas KM, Dang I, Yáñez A, Zhang W, Bresee C, Arditi M, Liu GY, Svendsen CN, Goodridge HS. PMID: 30820468; PMCID: PMC6382867.
      View in: PubMed   Mentions: 41  Translation:Animals
    27. Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining. Front Immunol. 2018; 9:2925. Saylor J, Ma Z, Goodridge HS, Huang F, Cress AE, Pandol SJ, Shiao SL, Vidal AC, Wu L, Nickols NG, Gertych A, Knudsen BS. PMID: 30619287; PMCID: PMC6302234.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    28. Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging. Aging (Albany NY). 2018 11 18; 10(11):3327-3352. Crupi AN, Nunnelee JS, Taylor DJ, Thomas A, Vit JP, Riera CE, Gottlieb RA, Goodridge HS. PMID: 30449736; PMCID: PMC6286850.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    29. Identification and Isolation of Oligopotent and Lineage-committed Myeloid Progenitors from Mouse Bone Marrow. J Vis Exp. 2018 07 29; (137). Yáñez A, Goodridge HS. PMID: 30102291; PMCID: PMC6126592.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    30. Mast Cells Reveal Their Past Selves. Immunity. 2018 06 19; 48(6):1065-1067. Wolf AA, Goodridge HS. PMID: 29924968.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    31. Reticulon-1 and Reduced Migration toward Chemoattractants by Macrophages Differentiated from the Bone Marrow of Ultraviolet-Irradiated and Ultraviolet-Chimeric Mice. J Immunol. 2018 01 01; 200(1):260-270. McGonigle TA, Dwyer AR, Greenland EL, Scott NM, Carter KW, Keane KN, Newsholme P, Goodridge HS, Pixley FJ, Hart PH. PMID: 29167231.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    32. Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes. Immunity. 2017 11 21; 47(5):890-902.e4. Yáñez A, Coetzee SG, Olsson A, Muench DE, Berman BP, Hazelett DJ, Salomonis N, Grimes HL, Goodridge HS. PMID: 29166589; PMCID: PMC5726802.
      View in: PubMed   Mentions: 198     Fields:    Translation:AnimalsCells
    33. PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo. Exp Hematol. 2017 12; 56:64-68. McGonigle TA, Dwyer AR, Greenland EL, Scott NM, Keane KN, Newsholme P, Goodridge HS, Zon LI, Pixley FJ, Hart PH. PMID: 28822771; PMCID: PMC5972521.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    34. Counting the cost of lineage decisions. Nat Immunol. 2017 07 19; 18(8):872-873. Yáñez A, Goodridge HS, Grimes HL. PMID: 28722717.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    35. UV Irradiation of Skin Enhances Glycolytic Flux and Reduces Migration Capabilities in Bone Marrow-Differentiated Dendritic Cells. Am J Pathol. 2017 Sep; 187(9):2046-2059. McGonigle TA, Keane KN, Ghaly S, Carter KW, Anderson D, Scott NM, Goodridge HS, Dwyer A, Greenland E, Pixley FJ, Newsholme P, Hart PH. PMID: 28708972.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    36. Autocrine Type I IFN Signaling in Dendritic Cells Stimulated with Fungal β-Glucans or Lipopolysaccharide Promotes CD8 T Cell Activation. J Immunol. 2017 01 01; 198(1):375-382. Hassanzadeh-Kiabi N, Yáñez A, Dang I, Martins GA, Underhill DM, Goodridge HS. PMID: 27872213; PMCID: PMC5173402.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    37. Harnessing the beneficial heterologous effects of vaccination. Nat Rev Immunol. 2016 06; 16(6):392-400. Goodridge HS, Ahmed SS, Curtis N, Kollmann TR, Levy O, Netea MG, Pollard AJ, van Crevel R, Wilson CB. PMID: 27157064; PMCID: PMC4931283.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsPHPublic Health
    38. C9orf72 is required for proper macrophage and microglial function in mice. Science. 2016 Mar 18; 351(6279):1324-9. O'Rourke JG, Bogdanik L, Yáñez A, Lall D, Wolf AJ, Muhammad AK, Ho R, Carmona S, Vit JP, Zarrow J, Kim KJ, Bell S, Harms MB, Miller TM, Dangler CA, Underhill DM, Goodridge HS, Lutz CM, Baloh RH. PMID: 26989253; PMCID: PMC5120541.
      View in: PubMed   Mentions: 298     Fields:    Translation:HumansAnimalsCells
    39. TLR2, TLR4 and Dectin-1 signalling in hematopoietic stem and progenitor cells determines the antifungal phenotype of the macrophages they produce. Microbes Infect. 2016 05; 18(5):354-63. Megías J, Martínez A, Yáñez A, Goodridge HS, Gozalbo D, Gil ML. PMID: 26828664.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    40. Interferon regulatory factor 8 and the regulation of neutrophil, monocyte, and dendritic cell production. Curr Opin Hematol. 2016 Jan; 23(1):11-7. Yáñez A, Goodridge HS. PMID: 26554887.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    41. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. Elife. 2015 Oct 30; 4. Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. PMID: 26517880; PMCID: PMC4626889.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    42. IRF8 acts in lineage-committed rather than oligopotent progenitors to control neutrophil vs monocyte production. Blood. 2015 Feb 26; 125(9):1452-9. Yáñez A, Ng MY, Hassanzadeh-Kiabi N, Goodridge HS. PMID: 25597637.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    43. Gut microbiota promote hematopoiesis to control bacterial infection. Cell Host Microbe. 2014 Mar 12; 15(3):374-81. Khosravi A, Yáñez A, Price JG, Chow A, Merad M, Goodridge HS, Mazmanian SK. PMID: 24629343; PMCID: PMC4144825.
      View in: PubMed   Mentions: 315     Fields:    Translation:Animals
    44. Editorial: Bone marrow progenitors share their experiences with their offspring. J Leukoc Biol. 2014 Feb; 95(2):201-4. Goodridge HS. PMID: 24482486.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    45. Induced pluripotent stem cell-derived myeloid phagocytes: disease modeling and therapeutic applications. Drug Discov Today. 2014 Jun; 19(6):774-80. Goodridge HS. PMID: 24445266.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    46. TLRs control hematopoiesis during infection. Eur J Immunol. 2013 Oct; 43(10):2526-33. Yáñez A, Goodridge HS, Gozalbo D, Gil ML. PMID: 24122753; PMCID: PMC4152461.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    47. Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce. Eur J Immunol. 2013 Aug; 43(8):2114-25. Yáñez A, Hassanzadeh-Kiabi N, Ng MY, Megías J, Subramanian A, Liu GY, Underhill DM, Gil ML, Goodridge HS. PMID: 23661549; PMCID: PMC3783206.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    48. Mechanisms of Fc receptor and dectin-1 activation for phagocytosis. Traffic. 2012 Aug; 13(8):1062-71. Goodridge HS, Underhill DM, Touret N. PMID: 22624959.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    49. Information processing during phagocytosis. Nat Rev Immunol. 2012 Jun 15; 12(7):492-502. Underhill DM, Goodridge HS. PMID: 22699831; PMCID: PMC5570470.
      View in: PubMed   Mentions: 238     Fields:    Translation:HumansAnimalsCells
    50. Receptor usage by the Acanthocheilonema viteae-derived immunomodulator, ES-62. Exp Parasitol. 2012 Sep; 132(1):97-102. Harnett W, Goodridge HS, Allen JM, Harnett M. PMID: 21925176.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    51. Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature. 2011 Apr 28; 472(7344):471-5. Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan AS, Magee AS, Danielson ME, Weiss A, Vasilakos JP, Underhill DM. PMID: 21525931; PMCID: PMC3084546.
      View in: PubMed   Mentions: 350     Fields:    Translation:HumansAnimalsCells
    52. Angiotensin-converting enzyme overexpression in mouse myelomonocytic cells augments resistance to Listeria and methicillin-resistant Staphylococcus aureus. J Biol Chem. 2010 Dec 10; 285(50):39051-60. Okwan-Duodu D, Datta V, Shen XZ, Goodridge HS, Bernstein EA, Fuchs S, Liu GY, Bernstein KE. PMID: 20937811; PMCID: PMC2998083.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    53. Adaptor protein Lnk inhibits c-Fms-mediated macrophage function. J Leukoc Biol. 2010 Oct; 88(4):699-706. Gueller S, Goodridge HS, Niebuhr B, Xing H, Koren-Michowitz M, Serve H, Underhill DM, Brandts CH, Koeffler HP. PMID: 20571037; PMCID: PMC3218676.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    54. Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. Cell Host Microbe. 2010 Jan 21; 7(1):38-49. Shimada T, Park BG, Wolf AJ, Brikos C, Goodridge HS, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM. PMID: 20114027; PMCID: PMC2818986.
      View in: PubMed   Mentions: 147     Fields:    Translation:AnimalsCells
    55. Beta-glucan recognition by the innate immune system. Immunol Rev. 2009 Jul; 230(1):38-50. Goodridge HS, Wolf AJ, Underhill DM. PMID: 19594628; PMCID: PMC6618291.
      View in: PubMed   Mentions: 210     Fields:    Translation:HumansAnimalsCells
    56. Differential use of CARD9 by dectin-1 in macrophages and dendritic cells. J Immunol. 2009 Jan 15; 182(2):1146-54. Goodridge HS, Shimada T, Wolf AJ, Hsu YM, Becker CA, Lin X, Underhill DM. PMID: 19124758; PMCID: PMC2718573.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansAnimalsCells
    57. STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes. J Cell Sci. 2008 Feb 01; 121(Pt 3):272-81. Krejci P, Salazar L, Goodridge HS, Kashiwada TA, Schibler MJ, Jelinkova P, Thompson LM, Wilcox WR. PMID: 18198189.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    58. Fungal Recognition by TLR2 and Dectin-1. Handb Exp Pharmacol. 2008; (183):87-109. Goodridge HS, Underhill DM. PMID: 18071656.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimals
    59. Phosphorylcholine mimics the effects of ES-62 on macrophages and dendritic cells. Parasite Immunol. 2007 Mar; 29(3):127-37. Goodridge HS, McGuiness S, Houston KM, Egan CA, Al-Riyami L, Alcocer MJ, Harnett MM, Harnett W. PMID: 17266740.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    60. Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells. J Immunol. 2007 Mar 01; 178(5):3107-15. Goodridge HS, Simmons RM, Underhill DM. PMID: 17312158.
      View in: PubMed   Mentions: 179     Fields:    Translation:AnimalsCells
    61. The many faces of ITAMs. Trends Immunol. 2007 Feb; 28(2):66-73. Underhill DM, Goodridge HS. PMID: 17197236.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    62. CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway. J Immunol. 2006 Oct 01; 177(7):4473-80. Sester DP, Brion K, Trieu A, Goodridge HS, Roberts TL, Dunn J, Hume DA, Stacey KJ, Sweet MJ. PMID: 16982883.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    63. Differential polarization of immune responses by plant 2S seed albumins, Ber e 1, and SFA8. J Immunol. 2006 Aug 01; 177(3):1561-6. Kean DE, Goodridge HS, McGuinness S, Harnett MM, Alcocer MJ, Harnett W. PMID: 16849463.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    64. Signalling mechanisms underlying subversion of the immune response by the filarial nematode secreted product ES-62. Immunology. 2005 Jul; 115(3):296-304. Goodridge HS, Stepek G, Harnett W, Harnett MM. PMID: 15946247; PMCID: PMC1782160.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    65. Introduction to immune cell signalling. Parasitology. 2005; 130 Suppl:S3-9. Goodridge HS, Harnett MM. PMID: 16281990.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    66. Subversion of immune cell signal transduction pathways by the secreted filarial nematode product, ES-62. Parasitology. 2005; 130 Suppl:S63-8. Harnett W, Goodridge HS, Harnett MM. PMID: 16281993.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
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    72. Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses. Immunology. 2003 Jul; 109(3):415-25. Goodridge HS, Harnett W, Liew FY, Harnett MM. PMID: 12807488; PMCID: PMC1782981.
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    73. A novel MyD-1 (SIRP-1alpha) signaling pathway that inhibits LPS-induced TNFalpha production by monocytes. Blood. 2003 Oct 01; 102(7):2532-40. Smith RE, Patel V, Seatter SD, Deehan MR, Brown MH, Brooke GP, Goodridge HS, Howard CJ, Rigley KP, Harnett W, Harnett MM. PMID: 12805067.
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    76. Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. J Immunol. 1999 Dec 15; 163(12):6403-12. Feng GJ, Goodridge HS, Harnett MM, Wei XQ, Nikolaev AV, Higson AP, Liew FY. PMID: 10586030.
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