Helen Sara Goodridge

Title(s)Adjunct Professor, Medicine
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Monocyte Production by Bone Marrow Progenitors
    NIH R01AI134987May 15, 2018 - Apr 30, 2023
    Role: Principal Investigator
    Effects of Microbial Exposure on Myelopoiesis
    NIH R21AI082379Sep 18, 2010 - Aug 31, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. BATF3 Protects Against Metabolic Syndrome and Maintains Intestinal Epithelial Homeostasis. Front Immunol. 2022; 13:841065. Hamade H, Stamps JT, Stamps DT, More SK, Thomas LS, Blackwood AY, Lahcene NL, Castanon SL, Salumbides BC, Shimodaira Y, Goodridge HS, Targan SR, Michelsen KS. PMID: 35812447; PMCID: PMC9257242.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity. Cell Rep. 2022 Jun 21; 39(12):110977. Tessaro FHG, Ko EY, De Simone M, Piras R, Broz MT, Goodridge HS, Balzer B, Shiao SL, Guarnerio J. PMID: 35732118; PMCID: PMC9249098.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    3. Demographic and clinical characteristics associated with variations in antibody response to BNT162b2 COVID-19 vaccination among healthcare workers at an academic medical centre: a longitudinal cohort analysis. BMJ Open. 2022 05 24; 12(5):e059994. Ebinger JE, Joung S, Liu Y, Wu M, Weber B, Claggett B, Botting PG, Sun N, Driver M, Kao YH, Khuu B, Wynter T, Nguyen TT, Alotaibi M, Prostko JC, Frias EC, Stewart JL, Goodridge HS, Chen P, Jordan SC, Jain M, Sharma S, Fert-Bober J, Van Eyk JE, Minissian MB, Arditi M, Melmed GY, Braun JG, McGovern DPB, Cheng S, Sobhani K. PMID: 35613792; PMCID: PMC9130668.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    4. Neutrophil phenotypes and functions in cancer: A consensus statement. J Exp Med. 2022 06 06; 219(6). Quail DF, Amulic B, Aziz M, Barnes BJ, Eruslanov E, Fridlender ZG, Goodridge HS, Granot Z, Hidalgo A, Huttenlocher A, Kaplan MJ, Malanchi I, Merghoub T, Meylan E, Mittal V, Pittet MJ, Rubio-Ponce A, Udalova IA, van den Berg TK, Wagner DD, Wang P, Zychlinsky A, de Visser KE, Egeblad M, Kubes P. PMID: 35522219; PMCID: PMC9086501.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Heterogeneity and origins of myeloid cells. Curr Opin Hematol. 2022 07 01; 29(4):201-208. Yáñez A, Bono C, Goodridge HS. PMID: 35285448; PMCID: PMC9256773.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Microbial Sensing by Hematopoietic Stem and Progenitor Cells. Stem Cells. 2022 03 03; 40(1):14-21. Barman PK, Goodridge HS. PMID: 35511863; PMCID: PMC9072977.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    7. COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver. Cell Rep. 2021 11 16; 37(7):110026. Cohen K, Mouhadeb O, Ben Shlomo S, Langer M, Neumann A, Erez N, Moshkovits I, Pelet R, Kedar DJ, Brazowski E, Guilliams M, Goodridge HS, Gluck N, Varol C. PMID: 34788631; PMCID: PMC8998879.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Sample processing and single cell RNA-sequencing of peripheral blood immune cells from COVID-19 patients. STAR Protoc. 2021 06 18; 2(2):100582. Yao C, Bora SA, Chen P, Goodridge HS, Gharib SA. PMID: 34002169; PMCID: PMC8114807.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. Cell-type-specific immune dysregulation in severely ill COVID-19 patients. Cell Rep. 2021 Mar 30; 34(13):108943. Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Surapaneni NS, Matusov YP, Chiang GC, Kassar AG, Patel N, Green CER, Aziz AW, Suri H, Suda J, Lopez AA, Martins GA, Stripp BR, Gharib SA, Goodridge HS, Chen P. PMID: 33789116; PMCID: PMC8009498.
      View in: PubMed   Mentions: 5     Fields:    
    10. Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients. Cell Rep. 2021 01 05; 34(1):108590. Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Surapaneni NS, Matusov YP, Cerro Chiang G, Kassar AG, Patel N, Green CER, Aziz AW, Suri H, Suda J, Lopez AA, Martins GA, Stripp BR, Gharib SA, Goodridge HS, Chen P. PMID: 33357411; PMCID: PMC7744012.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    11. Cell type-specific immune dysregulation in severely ill COVID-19 patients. medRxiv. 2020 Jul 24. Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Surapaneni NS, Matusov YP, Chiang GC, Kassar AG, Patel N, Green CE, Aziz AW, Suri H, Suda J, Lopez AA, Martins GA, Stripp BR, Gharib SA, Goodridge HS, Chen P. PMID: 32743611; PMCID: PMC7386732.
      View in: PubMed   Mentions:
    12. TLR2 and Dectin-1 Signaling in Mouse Hematopoietic Stem and Progenitor Cells Impacts the Ability of the Antigen Presenting Cells They Produce to Activate CD4 T Cells. Cells. 2020 05 25; 9(5). Martínez A, Bono C, Gozalbo D, Goodridge HS, Gil ML, Yáñez A. PMID: 32466296; PMCID: PMC7290964.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    13. Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls. iScience. 2020 Jun 26; 23(6):101192. Zhao W, Beers DR, Thonhoff JR, Thome AD, Faridar A, Wang J, Wen S, Ornelas L, Sareen D, Goodridge HS, Svendsen CN, Appel SH. PMID: 32521508; PMCID: PMC7286967.
      View in: PubMed   Mentions: 12  
    14. Rejuvenating the blood and bone marrow to slow aging-associated cognitive decline and Alzheimer's disease. Commun Biol. 2020 02 13; 3(1):69. Kang S, Moser VA, Svendsen CN, Goodridge HS. PMID: 32054965; PMCID: PMC7018752.
      View in: PubMed   Mentions: 3  Translation:HumansAnimals
    15. The Ontogeny of Monocyte Subsets. Front Immunol. 2019; 10:1642. Wolf AA, Yáñez A, Barman PK, Goodridge HS. PMID: 31379841; PMCID: PMC6650567.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    16. Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans. Obesity (Silver Spring). 2019 03; 27(3):434-443. Ehrhardt N, Cui J, Dagdeviren S, Saengnipanthkul S, Goodridge HS, Kim JK, Lantier L, Guo X, Chen YI, Raffel LJ, Buchanan TA, Hsueh WA, Rotter JI, Goodarzi MO, Péterfy M. PMID: 30801985; PMCID: PMC6474357.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    17. Young bone marrow transplantation preserves learning and memory in old mice. Commun Biol. 2019; 2:73. Das MM, Godoy M, Chen S, Moser VA, Avalos P, Roxas KM, Dang I, Yáñez A, Zhang W, Bresee C, Arditi M, Liu GY, Svendsen CN, Goodridge HS. PMID: 30820468; PMCID: PMC6382867.
      View in: PubMed   Mentions: 20  Translation:Animals
    18. Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining. Front Immunol. 2018; 9:2925. Saylor J, Ma Z, Goodridge HS, Huang F, Cress AE, Pandol SJ, Shiao SL, Vidal AC, Wu L, Nickols NG, Gertych A, Knudsen BS. PMID: 30619287; PMCID: PMC6302234.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    19. Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging. Aging (Albany NY). 2018 11 18; 10(11):3327-3352. Crupi AN, Nunnelee JS, Taylor DJ, Thomas A, Vit JP, Riera CE, Gottlieb RA, Goodridge HS. PMID: 30449736; PMCID: PMC6286850.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    20. Identification and Isolation of Oligopotent and Lineage-committed Myeloid Progenitors from Mouse Bone Marrow. J Vis Exp. 2018 07 29; (137). Yáñez A, Goodridge HS. PMID: 30102291; PMCID: PMC6126592.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    21. Mast Cells Reveal Their Past Selves. Immunity. 2018 06 19; 48(6):1065-1067. Wolf AA, Goodridge HS. PMID: 29924968.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Reticulon-1 and Reduced Migration toward Chemoattractants by Macrophages Differentiated from the Bone Marrow of Ultraviolet-Irradiated and Ultraviolet-Chimeric Mice. J Immunol. 2018 01 01; 200(1):260-270. McGonigle TA, Dwyer AR, Greenland EL, Scott NM, Carter KW, Keane KN, Newsholme P, Goodridge HS, Pixley FJ, Hart PH. PMID: 29167231.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    23. Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes. Immunity. 2017 11 21; 47(5):890-902.e4. Yáñez A, Coetzee SG, Olsson A, Muench DE, Berman BP, Hazelett DJ, Salomonis N, Grimes HL, Goodridge HS. PMID: 29166589; PMCID: PMC5726802.
      View in: PubMed   Mentions: 117     Fields:    Translation:AnimalsCells
    24. PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo. Exp Hematol. 2017 12; 56:64-68. McGonigle TA, Dwyer AR, Greenland EL, Scott NM, Keane KN, Newsholme P, Goodridge HS, Zon LI, Pixley FJ, Hart PH. PMID: 28822771; PMCID: PMC5972521.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    25. Counting the cost of lineage decisions. Nat Immunol. 2017 07 19; 18(8):872-873. Yáñez A, Goodridge HS, Grimes HL. PMID: 28722717.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    26. UV Irradiation of Skin Enhances Glycolytic Flux and Reduces Migration Capabilities in Bone Marrow-Differentiated Dendritic Cells. Am J Pathol. 2017 Sep; 187(9):2046-2059. McGonigle TA, Keane KN, Ghaly S, Carter KW, Anderson D, Scott NM, Goodridge HS, Dwyer A, Greenland E, Pixley FJ, Newsholme P, Hart PH. PMID: 28708972.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    27. Autocrine Type I IFN Signaling in Dendritic Cells Stimulated with Fungal β-Glucans or Lipopolysaccharide Promotes CD8 T Cell Activation. J Immunol. 2017 01 01; 198(1):375-382. Hassanzadeh-Kiabi N, Yáñez A, Dang I, Martins GA, Underhill DM, Goodridge HS. PMID: 27872213; PMCID: PMC5173402.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    28. Harnessing the beneficial heterologous effects of vaccination. Nat Rev Immunol. 2016 06; 16(6):392-400. Goodridge HS, Ahmed SS, Curtis N, Kollmann TR, Levy O, Netea MG, Pollard AJ, van Crevel R, Wilson CB. PMID: 27157064; PMCID: PMC4931283.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsPHPublic Health
    29. C9orf72 is required for proper macrophage and microglial function in mice. Science. 2016 Mar 18; 351(6279):1324-9. O'Rourke JG, Bogdanik L, Yáñez A, Lall D, Wolf AJ, Muhammad AK, Ho R, Carmona S, Vit JP, Zarrow J, Kim KJ, Bell S, Harms MB, Miller TM, Dangler CA, Underhill DM, Goodridge HS, Lutz CM, Baloh RH. PMID: 26989253; PMCID: PMC5120541.
      View in: PubMed   Mentions: 240     Fields:    Translation:HumansAnimalsCells
    30. TLR2, TLR4 and Dectin-1 signalling in hematopoietic stem and progenitor cells determines the antifungal phenotype of the macrophages they produce. Microbes Infect. 2016 05; 18(5):354-63. Megías J, Martínez A, Yáñez A, Goodridge HS, Gozalbo D, Gil ML. PMID: 26828664.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    31. Interferon regulatory factor 8 and the regulation of neutrophil, monocyte, and dendritic cell production. Curr Opin Hematol. 2016 Jan; 23(1):11-7. Yáñez A, Goodridge HS. PMID: 26554887.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    32. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. Elife. 2015 Oct 30; 4. Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. PMID: 26517880; PMCID: PMC4626889.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    33. IRF8 acts in lineage-committed rather than oligopotent progenitors to control neutrophil vs monocyte production. Blood. 2015 Feb 26; 125(9):1452-9. Yáñez A, Ng MY, Hassanzadeh-Kiabi N, Goodridge HS. PMID: 25597637.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    34. Gut microbiota promote hematopoiesis to control bacterial infection. Cell Host Microbe. 2014 Mar 12; 15(3):374-81. Khosravi A, Yáñez A, Price JG, Chow A, Merad M, Goodridge HS, Mazmanian SK. PMID: 24629343; PMCID: PMC4144825.
      View in: PubMed   Mentions: 242     Fields:    Translation:Animals
    35. Editorial: Bone marrow progenitors share their experiences with their offspring. J Leukoc Biol. 2014 Feb; 95(2):201-4. Goodridge HS. PMID: 24482486.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    36. Induced pluripotent stem cell-derived myeloid phagocytes: disease modeling and therapeutic applications. Drug Discov Today. 2014 Jun; 19(6):774-80. Goodridge HS. PMID: 24445266.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    37. TLRs control hematopoiesis during infection. Eur J Immunol. 2013 Oct; 43(10):2526-33. Yáñez A, Goodridge HS, Gozalbo D, Gil ML. PMID: 24122753; PMCID: PMC4152461.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    38. Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce. Eur J Immunol. 2013 Aug; 43(8):2114-25. Yáñez A, Hassanzadeh-Kiabi N, Ng MY, Megías J, Subramanian A, Liu GY, Underhill DM, Gil ML, Goodridge HS. PMID: 23661549; PMCID: PMC3783206.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    39. Mechanisms of Fc receptor and dectin-1 activation for phagocytosis. Traffic. 2012 Aug; 13(8):1062-71. Goodridge HS, Underhill DM, Touret N. PMID: 22624959.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    40. Information processing during phagocytosis. Nat Rev Immunol. 2012 Jun 15; 12(7):492-502. Underhill DM, Goodridge HS. PMID: 22699831; PMCID: PMC5570470.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansAnimalsCells
    41. Receptor usage by the Acanthocheilonema viteae-derived immunomodulator, ES-62. Exp Parasitol. 2012 Sep; 132(1):97-102. Harnett W, Goodridge HS, Allen JM, Harnett M. PMID: 21925176.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    42. Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature. 2011 Apr 28; 472(7344):471-5. Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan AS, Magee AS, Danielson ME, Weiss A, Vasilakos JP, Underhill DM. PMID: 21525931; PMCID: PMC3084546.
      View in: PubMed   Mentions: 303     Fields:    Translation:HumansAnimalsCells
    43. Angiotensin-converting enzyme overexpression in mouse myelomonocytic cells augments resistance to Listeria and methicillin-resistant Staphylococcus aureus. J Biol Chem. 2010 Dec 10; 285(50):39051-60. Okwan-Duodu D, Datta V, Shen XZ, Goodridge HS, Bernstein EA, Fuchs S, Liu GY, Bernstein KE. PMID: 20937811; PMCID: PMC2998083.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    44. Adaptor protein Lnk inhibits c-Fms-mediated macrophage function. J Leukoc Biol. 2010 Oct; 88(4):699-706. Gueller S, Goodridge HS, Niebuhr B, Xing H, Koren-Michowitz M, Serve H, Underhill DM, Brandts CH, Koeffler HP. PMID: 20571037; PMCID: PMC3218676.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    45. Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. Cell Host Microbe. 2010 Jan 21; 7(1):38-49. Shimada T, Park BG, Wolf AJ, Brikos C, Goodridge HS, Becker CA, Reyes CN, Miao EA, Aderem A, Götz F, Liu GY, Underhill DM. PMID: 20114027; PMCID: PMC2818986.
      View in: PubMed   Mentions: 124     Fields:    Translation:AnimalsCells
    46. Beta-glucan recognition by the innate immune system. Immunol Rev. 2009 Jul; 230(1):38-50. Goodridge HS, Wolf AJ, Underhill DM. PMID: 19594628; PMCID: PMC6618291.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimalsCells
    47. Differential use of CARD9 by dectin-1 in macrophages and dendritic cells. J Immunol. 2009 Jan 15; 182(2):1146-54. Goodridge HS, Shimada T, Wolf AJ, Hsu YM, Becker CA, Lin X, Underhill DM. PMID: 19124758; PMCID: PMC2718573.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    48. STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes. J Cell Sci. 2008 Feb 01; 121(Pt 3):272-81. Krejci P, Salazar L, Goodridge HS, Kashiwada TA, Schibler MJ, Jelinkova P, Thompson LM, Wilcox WR. PMID: 18198189.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    49. Fungal Recognition by TLR2 and Dectin-1. Handb Exp Pharmacol. 2008; (183):87-109. Goodridge HS, Underhill DM. PMID: 18071656.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimals
    50. Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells. J Immunol. 2007 Mar 01; 178(5):3107-15. Goodridge HS, Simmons RM, Underhill DM. PMID: 17312158.
      View in: PubMed   Mentions: 169     Fields:    Translation:AnimalsCells
    51. Phosphorylcholine mimics the effects of ES-62 on macrophages and dendritic cells. Parasite Immunol. 2007 Mar; 29(3):127-37. Goodridge HS, McGuiness S, Houston KM, Egan CA, Al-Riyami L, Alcocer MJ, Harnett MM, Harnett W. PMID: 17266740.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    52. The many faces of ITAMs. Trends Immunol. 2007 Feb; 28(2):66-73. Underhill DM, Goodridge HS. PMID: 17197236.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    53. CpG DNA activates survival in murine macrophages through TLR9 and the phosphatidylinositol 3-kinase-Akt pathway. J Immunol. 2006 Oct 01; 177(7):4473-80. Sester DP, Brion K, Trieu A, Goodridge HS, Roberts TL, Dunn J, Hume DA, Stacey KJ, Sweet MJ. PMID: 16982883.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    54. Differential polarization of immune responses by plant 2S seed albumins, Ber e 1, and SFA8. J Immunol. 2006 Aug 01; 177(3):1561-6. Kean DE, Goodridge HS, McGuinness S, Harnett MM, Alcocer MJ, Harnett W. PMID: 16849463.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    55. Signalling mechanisms underlying subversion of the immune response by the filarial nematode secreted product ES-62. Immunology. 2005 Jul; 115(3):296-304. Goodridge HS, Stepek G, Harnett W, Harnett MM. PMID: 15946247; PMCID: PMC1782160.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    56. Introduction to immune cell signalling. Parasitology. 2005; 130 Suppl:S3-9. Goodridge HS, Harnett MM. PMID: 16281990.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    57. Subversion of immune cell signal transduction pathways by the secreted filarial nematode product, ES-62. Parasitology. 2005; 130 Suppl:S63-8. Harnett W, Goodridge HS, Harnett MM. PMID: 16281993.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    58. Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62. J Immunol. 2005 Jan 01; 174(1):284-93. Goodridge HS, Marshall FA, Else KJ, Houston KM, Egan C, Al-Riyami L, Liew FY, Harnett W, Harnett MM. PMID: 15611251.
      View in: PubMed   Mentions: 106     Fields:    Translation:AnimalsCells
    59. Subversion of immunological signalling by a filarial nematode phosphorylcholine-containing secreted product. Cell Signal. 2005 Jan; 17(1):11-6. Goodridge HS, Deehan MR, Harnett W, Harnett MM. PMID: 15451020.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    60. In vivo exposure of murine dendritic cell and macrophage bone marrow progenitors to the phosphorylcholine-containing filarial nematode glycoprotein ES-62 polarizes their differentiation to an anti-inflammatory phenotype. Immunology. 2004 Dec; 113(4):491-8. Goodridge HS, Marshall FA, Wilson EH, Houston KM, Liew FY, Harnett MM, Harnett W. PMID: 15554927; PMCID: PMC1782600.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    61. Stage-specific and species-specific differences in the production of the mRNA and protein for the filarial nematode secreted product, ES-62. Parasitology. 2004 Jan; 128(Pt 1):91-8. Stepek G, Houston KM, Goodridge HS, Devaney E, Harnett W. PMID: 15002908.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    62. In vivo activation of murine peritoneal B1 cells by the filarial nematode phosphorylcholine-containing glycoprotein ES-62. Parasite Immunol. 2003 Aug-Sep; 25(8-9):463-6. Wilson EH, Katz E, Goodridge HS, Harnett MM, Harnett W. PMID: 14651594.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    63. Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses. Immunology. 2003 Jul; 109(3):415-25. Goodridge HS, Harnett W, Liew FY, Harnett MM. PMID: 12807488; PMCID: PMC1782981.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    64. A novel MyD-1 (SIRP-1alpha) signaling pathway that inhibits LPS-induced TNFalpha production by monocytes. Blood. 2003 Oct 01; 102(7):2532-40. Smith RE, Patel V, Seatter SD, Deehan MR, Brown MH, Brooke GP, Goodridge HS, Howard CJ, Rigley KP, Harnett W, Harnett MM. PMID: 12805067.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    65. Immunomodulatory properties of Ascaris suum glycosphingolipids - phosphorylcholine and non-phosphorylcholine-dependent effects. Parasite Immunol. 2002 Sep-Oct; 24(9-10):463-9. Deehan MR, Goodridge HS, Blair D, Lochnit G, Dennis RD, Geyer R, Harnett MM, Harnett W. PMID: 12654088.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    66. Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae. J Immunol. 2001 Jul 15; 167(2):940-5. Goodridge HS, Wilson EH, Harnett W, Campbell CC, Harnett MM, Liew FY. PMID: 11441102.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    67. Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. J Immunol. 1999 Dec 15; 163(12):6403-12. Feng GJ, Goodridge HS, Harnett MM, Wei XQ, Nikolaev AV, Higson AP, Liew FY. PMID: 10586030.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
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