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Inhibition of IL-1 Ameliorates Cardiac Dysfunction and Arrhythmias in a Murine Model of Kawasaki Disease. Arterioscler Thromb Vasc Biol. 2024 Feb 22.
Mesquita T, Lin YN, Chen S, Lee Y, Miguel-Dos-Santos R, Atici AE, Fishbein MC, Rivas MN, Arditi M, Cingolani E. PMID: 38385289.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Functional Hypothalamic Amenorrhea and Preclinical Cardiovascular Disease. J Clin Endocrinol Metab. 2023 Dec 21; 109(1):e51-e57.
Shufelt CL, Saadedine M, Cook-Wiens G, Pisarska MD, Manson JE, Berga SL, Arditi M, Shah PK, Bairey Merz CN. PMID: 37610989.
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PubMed Mentions: Fields:
Translation:
Humans
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Platelets exacerbate cardiovascular inflammation in a murine model of Kawasaki disease vasculitis. JCI Insight. 2023 07 24; 8(14).
Kocatürk B, Lee Y, Nosaka N, Abe M, Martinon D, Lane ME, Moreira D, Chen S, Fishbein MC, Porritt RA, Franklin BS, Noval Rivas M, Arditi M. PMID: 37279077; PMCID: PMC10443810.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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The role of trained immunity in COVID-19: Lessons for the next pandemic. Cell Host Microbe. 2023 06 14; 31(6):890-901.
Netea MG, Ziogas A, Benn CS, Giamarellos-Bourboulis EJ, Joosten LAB, Arditi M, Chumakov K, van Crevel R, Gallo R, Aaby P, van der Meer JWM. PMID: 37321172; PMCID: PMC10265767.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCellsPHPublic Health
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EGF-Receptor-Dependent TLR7 Signaling in Macrophages Promotes Glomerular Injury in Crescentic Glomerulonephritis. Lab Invest. 2023 09; 103(9):100190.
Tatsumoto N, Saito S, Rifkin IR, Bonegio RG, Leal DN, Sen GC, Arditi M, Yamashita M. PMID: 37268107; PMCID: PMC10527264.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Osteopontin depletion in macrophages perturbs proteostasis via regulating UCHL1-UPS axis and mitochondria-mediated apoptosis. Front Immunol. 2023; 14:1155935.
Rentsendorj A, Raedschelders K, Fuchs DT, Sheyn J, Vaibhav V, Porritt RA, Shi H, Dagvadorj J, de Freitas Germano J, Koronyo Y, Arditi M, Black KL, Gaire BP, Van Eyk JE, Koronyo-Hamaoui M. PMID: 37325640; PMCID: PMC10266348.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
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Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: Common Inflammatory Pathways of Two Distinct Diseases. Rheum Dis Clin North Am. 2023 08; 49(3):647-659.
Noval Rivas M, Arditi M. PMID: 37331738; PMCID: PMC10020039.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Increased Myosin light chain 9 expression during Kawasaki disease vasculitis. Front Immunol. 2022; 13:1036672.
Kobayashi H, Kimura MY, Hasegawa I, Suganuma E, Ikehara Y, Azuma K, Ito T, Ebata R, Kurashima Y, Kawasaki Y, Shiko Y, Saito N, Iwase H, Lee Y, Noval Rivas M, Arditi M, Zuka M, Hamada H, Nakayama T. PMID: 36685558; PMCID: PMC9853906.
View in:
PubMed Mentions:
1 Fields:
Translation:
Animals
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Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis. Circulation. 2023 03 14; 147(11):867-876.
Yonker LM, Swank Z, Bartsch YC, Burns MD, Kane A, Boribong BP, Davis JP, Loiselle M, Novak T, Senussi Y, Cheng CA, Burgess E, Edlow AG, Chou J, Dionne A, Balaguru D, Lahoud-Rahme M, Arditi M, Julg B, Randolph AG, Alter G, Fasano A, Walt DR. PMID: 36597886; PMCID: PMC10010667.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Notch1 signaling impairs regulatory T cells during multisystem inflammatory syndrome in children. J Clin Invest. 2023 01 03; 133(1).
Noval Rivas M, Arditi M. PMID: 36594470; PMCID: PMC9797332.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Risk of paediatric multisystem inflammatory syndrome (PIMS-TS) during the SARS-CoV-2 alpha and delta variant waves: National observational and modelling study, 2020-21, England. Front Pediatr. 2022; 10:1034280.
Shingleton J, Burton L, Williams HE, Finnie TJR, Bennett E, Birrell P, Kenny S, Watson-Koszel T, Viner R, Arditi M, DeAngelis D, Gent N, Ladhani SN. PMID: 36545670; PMCID: PMC9762156.
View in:
PubMed Mentions:
3
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The changing epidemiology of PIMS-TS across COVID-19 waves: prospective national surveillance, January 2021 to July 2022, England. J Infect. 2022 Dec; 85(6):702-769.
Shingleton J, Williams H, Oligbu G, Powell A, Cohen J, Arditi M, Watson-Koszel T, Kenny S, Gent N, Ladhani SN. PMID: 36273638; PMCID: PMC9583625.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Overexpressed angiotensin-converting enzyme in neutrophils suppresses glomerular damage in crescentic glomerulonephritis. Am J Physiol Renal Physiol. 2022 10 01; 323(4):F411-F424.
Saito S, Tatsumoto N, Cao DY, Nosaka N, Nishi H, Leal DN, Bernstein E, Shimada K, Arditi M, Bernstein KE, Yamashita M. PMID: 35979968; PMCID: PMC9484997.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Non-protective immune imprint underlies failure of Staphylococcus aureus IsdB vaccine. Cell Host Microbe. 2022 08 10; 30(8):1163-1172.e6.
Tsai CM, Caldera JR, Hajam IA, Chiang AWT, Tsai CH, Li H, Díez ML, Gonzalez C, Trieu D, Martins GA, Underhill DM, Arditi M, Lewis NE, Liu GY. PMID: 35803276; PMCID: PMC9378590.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Multisystem Inflammatory Syndrome in Children and Long COVID: The SARS-CoV-2 Viral Superantigen Hypothesis. Front Immunol. 2022; 13:941009.
Noval Rivas M, Porritt RA, Cheng MH, Bahar I, Arditi M. PMID: 35874696; PMCID: PMC9300823.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansCells
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Demographic and clinical characteristics associated with variations in antibody response to BNT162b2 COVID-19 vaccination among healthcare workers at an academic medical centre: a longitudinal cohort analysis. BMJ Open. 2022 05 24; 12(5):e059994.
Ebinger JE, Joung S, Liu Y, Wu M, Weber B, Claggett B, Botting PG, Sun N, Driver M, Kao YH, Khuu B, Wynter T, Nguyen TT, Alotaibi M, Prostko JC, Frias EC, Stewart JL, Goodridge HS, Chen P, Jordan SC, Jain M, Sharma S, Fert-Bober J, Van Eyk JE, Minissian MB, Arditi M, Melmed GY, Braun JG, McGovern DPB, Cheng S, Sobhani K. PMID: 35613792; PMCID: PMC9130668.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCellsPHPublic Health
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Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens. Lancet Gastroenterol Hepatol. 2022 07; 7(7):594-595.
Brodin P, Arditi M. PMID: 35576952; PMCID: PMC9106421.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Targeting IRE1 endoribonuclease activity alleviates cardiovascular lesions in a murine model of Kawasaki disease vasculitis. JCI Insight. 2022 03 22; 7(6).
Marek-Iannucci S, Yildirim AD, Hamid SM, Ozdemir AB, Gomez AC, Kocatürk B, Porritt RA, Fishbein MC, Iwawaki T, Noval Rivas M, Erbay E, Arditi M. PMID: 35167493; PMCID: PMC8986066.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Impact of new variants on SARS-CoV-2 infectivity and neutralization: A molecular assessment of the alterations in the spike-host protein interactions. iScience. 2022 Mar 18; 25(3):103939.
Cheng MH, Krieger JM, Banerjee A, Xiang Y, Kaynak B, Shi Y, Arditi M, Bahar I. PMID: 35194576; PMCID: PMC8851820.
View in:
PubMed Mentions:
19
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Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection. J Transl Med. 2021 12 30; 19(1):524.
Liu Y, Ebinger JE, Mostafa R, Budde P, Gajewski J, Walker B, Joung S, Wu M, Bräutigam M, Hesping F, Rupieper E, Schubert AS, Zucht HD, Braun J, Melmed GY, Sobhani K, Arditi M, Van Eyk JE, Cheng S, Fert-Bober J. PMID: 34965855; PMCID: PMC8716184.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCellsPHPublic Health
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Symptomology following mRNA vaccination against SARS-CoV-2. Prev Med. 2021 12; 153:106860.
Ebinger JE, Lan R, Sun N, Wu M, Joung S, Botwin GJ, Botting P, Al-Amili D, Aronow H, Beekley J, Coleman B, Contreras S, Cozen W, Davis J, Debbas P, Diaz J, Driver M, Fert-Bober J, Gu Q, Heath M, Herrera E, Hoang A, Hussain SK, Huynh C, Kim L, Kittleson M, Liu Y, Lloyd J, Luong E, Malladi B, Merchant A, Merin N, Mujukian A, Nguyen N, Nguyen TT, Pozdnyakova V, Rashid M, Raedschelders K, Reckamp KL, Rhoades K, Sternbach S, Vallejo R, White S, Tompkins R, Wong M, Arditi M, Figueiredo JC, Van Eyk JE, Miles PB, Chavira C, Shane R, Sobhani K, Melmed GY, McGovern DPB, Braun JG, Cheng S, Minissian MB. PMID: 34687733; PMCID: PMC8527734.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCellsPHPublic Health
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The autoimmune signature of hyperinflammatory multisystem inflammatory syndrome in children. J Clin Invest. 2021 10 15; 131(20).
Porritt RA, Binek A, Paschold L, Rivas MN, McArdle A, Yonker LM, Alter G, Chandnani HK, Lopez M, Fasano A, Van Eyk JE, Binder M, Arditi M. PMID: 34437303; PMCID: PMC8516454.
View in:
PubMed Mentions:
61 Fields:
Translation:
Humans
-
Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis. JCI Insight. 2021 09 22; 6(18).
Marek-Iannucci S, Ozdemir AB, Moreira D, Gomez AC, Lane M, Porritt RA, Lee Y, Shimada K, Abe M, Stotland A, Zemmour D, Parker S, Sanchez-Lopez E, Van Eyk J, Gottlieb RA, Fishbein MC, Karin M, Crother TR, Rivas MN, Arditi M. PMID: 34403365; PMCID: PMC8492304.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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NLRP3 Inflammasome Mediates Immune-Stromal Interactions in Vasculitis. Circ Res. 2021 10 15; 129(9):e183-e200.
Porritt RA, Zemmour D, Abe M, Lee Y, Narayanan M, Carvalho TT, Gomez AC, Martinon D, Santiskulvong C, Fishbein MC, Chen S, Crother TR, Shimada K, Arditi M, Noval Rivas M. PMID: 34517723; PMCID: PMC8555446.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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A systems-level study reveals host-targeted repurposable drugs against SARS-CoV-2 infection. Mol Syst Biol. 2021 08; 17(8):e10239.
Chen F, Shi Q, Pei F, Vogt A, Porritt RA, Garcia G, Gomez AC, Cheng MH, Schurdak ME, Liu B, Chan SY, Arumugaswami V, Stern AM, Taylor DL, Arditi M, Bahar I. PMID: 34339582; PMCID: PMC8328275.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier. J Clin Invest. 2021 07 15; 131(14).
Yonker LM, Gilboa T, Ogata AF, Senussi Y, Lazarovits R, Boribong BP, Bartsch YC, Loiselle M, Rivas MN, Porritt RA, Lima R, Davis JP, Farkas EJ, Burns MD, Young N, Mahajan VS, Hajizadeh S, Lopez XIH, Kreuzer J, Morris R, Martinez EE, Han I, Griswold K, Barry NC, Thompson DB, Church G, Edlow AG, Haas W, Pillai S, Arditi M, Alter G, Walt DR, Fasano A. PMID: 34032635; PMCID: PMC8279585.
View in:
PubMed Mentions:
104 Fields:
Translation:
HumansCells
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Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation. Immunity. 2021 07 13; 54(7):1463-1477.e11.
Xian H, Liu Y, Rundberg Nilsson A, Gatchalian R, Crother TR, Tourtellotte WG, Zhang Y, Aleman-Muench GR, Lewis G, Chen W, Kang S, Luevanos M, Trudler D, Lipton SA, Soroosh P, Teijaro J, de la Torre JC, Arditi M, Karin M, Sanchez-Lopez E. PMID: 34115964; PMCID: PMC8189765.
View in:
PubMed Mentions:
105 Fields:
Translation:
HumansAnimalsCells
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HLA class I-associated expansion of TRBV11-2 T cells in multisystem inflammatory syndrome in children. J Clin Invest. 2021 05 17; 131(10).
Porritt RA, Paschold L, Rivas MN, Cheng MH, Yonker LM, Chandnani H, Lopez M, Simnica D, Schultheiß C, Santiskulvong C, Van Eyk J, McCormick JK, Fasano A, Bahar I, Binder M, Arditi M. PMID: 33705359; PMCID: PMC8121516.
View in:
PubMed Mentions:
78 Fields:
Translation:
HumansCells
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MicroRNA-223 Regulates the Development of Cardiovascular Lesions in LCWE-Induced Murine Kawasaki Disease Vasculitis by Repressing the NLRP3 Inflammasome. Front Pediatr. 2021; 9:662953.
Maruyama D, Kocatürk B, Lee Y, Abe M, Lane M, Moreira D, Chen S, Fishbein MC, Porritt RA, Noval Rivas M, Arditi M. PMID: 34026693; PMCID: PMC8138581.
View in:
PubMed Mentions:
4
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A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro. Structure. 2021 09 02; 29(9):951-962.e3.
Cheng MH, Porritt RA, Rivas MN, Krieger JM, Ozdemir AB, Garcia G, Arumugaswami V, Fries BC, Arditi M, Bahar I. PMID: 33930306; PMCID: PMC8082696.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Inhibition of IL-6 in the LCWE Mouse Model of Kawasaki Disease Inhibits Acute Phase Reactant Serum Amyloid A but Fails to Attenuate Vasculitis. Front Immunol. 2021; 12:630196.
Porritt RA, Chase Huizar C, Dick EJ, Kumar S, Escalona R, Gomez AC, Marek-Iannucci S, Noval Rivas M, Patterson J, Forsthuber TG, Arditi M, Gorelik M. PMID: 33897686; PMCID: PMC8064710.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Characterization of the T Cell Response to Lactobacillus casei Cell Wall Extract in Children With Kawasaki Disease and Its Potential Role in Vascular Inflammation. Front Pediatr. 2021; 9:633244.
Hsieh LE, Tremoulet AH, Burns JC, Noval Rivas M, Arditi M, Franco A. PMID: 33681107; PMCID: PMC7933244.
View in:
PubMed Mentions:
1
-
Seroprevalence of antibodies to SARS-CoV-2 in healthcare workers: a cross-sectional study. BMJ Open. 2021 02 12; 11(2):e043584.
Ebinger JE, Botwin GJ, Albert CM, Alotaibi M, Arditi M, Berg AH, Binek A, Botting P, Fert-Bober J, Figueiredo JC, Grein JD, Hasan W, Henglin M, Hussain SK, Jain M, Joung S, Karin M, Kim EH, Li D, Liu Y, Luong E, McGovern DPB, Merchant A, Merin N, Miles PB, Minissian M, Nguyen TT, Raedschelders K, Rashid MA, Riera CE, Riggs RV, Sharma S, Sternbach S, Sun N, Tourtellotte WG, Van Eyk JE, Sobhani K, Braun JG, Cheng S. PMID: 33579769; PMCID: PMC7883610.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus. Commun Biol. 2021 01 29; 4(1):129.
Dogan M, Kozhaya L, Placek L, Gunter C, Yigit M, Hardy R, Plassmeyer M, Coatney P, Lillard K, Bukhari Z, Kleinberg M, Hayes C, Arditi M, Klapper E, Merin N, Liang BT, Gupta R, Alpan O, Unutmaz D. PMID: 33514825; PMCID: PMC7846565.
View in:
PubMed Mentions:
66 Translation:
HumansCells
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BCG vaccination history associates with decreased SARS-CoV-2 seroprevalence across a diverse cohort of health care workers. J Clin Invest. 2021 01 19; 131(2).
Rivas MN, Ebinger JE, Wu M, Sun N, Braun J, Sobhani K, Van Eyk JE, Cheng S, Arditi M. PMID: 33211672; PMCID: PMC7810479.
View in:
PubMed Mentions:
80 Fields:
Translation:
Humans
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Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation. Proc Natl Acad Sci U S A. 2021 01 05; 118(1).
Dagvadorj J, Mikulska-Ruminska K, Tumurkhuu G, Ratsimandresy RA, Carriere J, Andres AM, Marek-Iannucci S, Song Y, Chen S, Lane M, Dorfleutner A, Gottlieb RA, Stehlik C, Cassel S, Sutterwala FS, Bahar I, Crother TR, Arditi M. PMID: 33361152; PMCID: PMC7817159.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro. bioRxiv. 2020 Nov 24.
Cheng MH, Porritt RA, Rivas MN, Krieger JM, Ozdemir AB, Garcia G, Arumugaswami V, Fries BC, Arditi M, Bahar I. PMID: 33269352; PMCID: PMC7709177.
View in:
PubMed Mentions:
1
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Phase II Open Label Study of Anakinra in Intravenous Immunoglobulin-Resistant Kawasaki Disease. Arthritis Rheumatol. 2021 01; 73(1):151-161.
Koné-Paut I, Tellier S, Belot A, Brochard K, Guitton C, Marie I, Meinzer U, Cherqaoui B, Galeotti C, Boukhedouni N, Agostini H, Arditi M, Lambert V, Piedvache C. PMID: 32779863.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansCTClinical Trials
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Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome. bioRxiv. 2020 Nov 09.
Porritt RA, Paschold L, Noval Rivas M, Hongying Cheng M, Yonker LM, Chandnani H, Lopez M, Simnica D, Schultheiß C, Santiskulvong C, Van Eyk J, Fasano A, Bahar I, Binder M, Arditi M. PMID: 33200133; PMCID: PMC7668738.
View in:
PubMed Mentions:
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Immune pathogenesis of COVID-19-related multisystem inflammatory syndrome in children. J Clin Invest. 2020 Nov 02; 130(11):5619-5621.
Rowley AH, Shulman ST, Arditi M. PMID: 32870815; PMCID: PMC7598032.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCellsPHPublic Health
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Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growth. EMBO Rep. 2020 12 03; 21(12):e51462.
Hamid SM, Citir M, Terzi EM, Cimen I, Yildirim Z, Dogan AE, Kocaturk B, Onat UI, Arditi M, Weber C, Traynor-Kaplan A, Schultz C, Erbay E. PMID: 33140520; PMCID: PMC7726810.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Multisystem Inflammatory Syndrome in Children in the United States. N Engl J Med. 2020 10 29; 383(18):1794.
Arditi M, Bahar I. PMID: 33085853.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansPHPublic Health
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COVID-19-associated multisystem inflammatory syndrome in children (MIS-C): A novel disease that mimics toxic shock syndrome-the superantigen hypothesis. J Allergy Clin Immunol. 2021 01; 147(1):57-59.
Noval Rivas M, Porritt RA, Cheng MH, Bahar I, Arditi M. PMID: 33075409; PMCID: PMC7564502.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
-
Novel SARS-CoV-2 specific antibody and neutralization assays reveal wide range of humoral immune response during COVID-19. medRxiv. 2020 Oct 14.
Dogan M, Kozhaya L, Placek L, Gunter CL, Yigit M, Hardy R, Plassmeyer M, Coatney P, Lillard K, Bukhari Z, Kleinberg M, Hayes C, Arditi M, Klapper E, Merin N, Liang BT, Gupta R, Alpan O, Unutmaz D. PMID: 32676617; PMCID: PMC7359542.
View in:
PubMed Mentions:
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Superantigenic character of an insert unique to SARS-CoV-2 spike supported by skewed TCR repertoire in patients with hyperinflammation. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25254-25262.
Cheng MH, Zhang S, Porritt RA, Noval Rivas M, Paschold L, Willscher E, Binder M, Arditi M, Bahar I. PMID: 32989130; PMCID: PMC7568239.
View in:
PubMed Mentions:
148 Fields:
Translation:
HumansCellsPHPublic Health
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Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model. Front Immunol. 2020; 11:554725.
Tumurkhuu G, Chen S, Montano EN, Ercan Laguna D, De Los Santos G, Yu JM, Lane M, Yamashita M, Markman JL, Blanco LP, Kaplan MJ, Shimada K, Crother TR, Ishimori M, Wallace DJ, Jefferies CA, Arditi M. PMID: 33072095; PMCID: PMC7541920.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
C9orf72 in myeloid cells suppresses STING-induced inflammation. Nature. 2020 09; 585(7823):96-101.
McCauley ME, O'Rourke JG, Yáñez A, Markman JL, Ho R, Wang X, Chen S, Lall D, Jin M, Muhammad AKMG, Bell S, Landeros J, Valencia V, Harms M, Arditi M, Jefferies C, Baloh RH. PMID: 32814898; PMCID: PMC7484469.
View in:
PubMed Mentions:
112 Fields:
Translation:
HumansAnimalsCells
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Kawasaki disease: pathophysiology and insights from mouse models. Nat Rev Rheumatol. 2020 07; 16(7):391-405.
Noval Rivas M, Arditi M. PMID: 32457494; PMCID: PMC7250272.
View in:
PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCells
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An insertion unique to SARS-CoV-2 exhibits superantigenic character strengthened by recent mutations. bioRxiv. 2020 May 21.
Cheng MH, Zhang S, Porritt RA, Arditi M, Bahar I. PMID: 32511374; PMCID: PMC7263503.
View in:
PubMed Mentions:
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Sex-Specific Effects of the Nlrp3 Inflammasome on Atherogenesis in LDL Receptor-Deficient Mice. JACC Basic Transl Sci. 2020 Jun; 5(6):582-598.
Chen S, Markman JL, Shimada K, Crother TR, Lane M, Abolhesn A, Shah PK, Arditi M. PMID: 32613145; PMCID: PMC7315187.
View in:
PubMed Mentions:
23
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Platelets Fuel the Inflammasome Activation of Innate Immune Cells. Cell Rep. 2020 05 12; 31(6):107615.
Rolfes V, Ribeiro LS, Hawwari I, Böttcher L, Rosero N, Maasewerd S, Santos MLS, Próchnicki T, Silva CMS, Wanderley CWS, Rothe M, Schmidt SV, Stunden HJ, Bertheloot D, Rivas MN, Fontes CJ, Carvalho LH, Cunha FQ, Latz E, Arditi M, Franklin BS. PMID: 32402278; PMCID: PMC7225754.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Loss of testosterone impairs anti-tumor neutrophil function. Nat Commun. 2020 03 31; 11(1):1613.
Markman JL, Porritt RA, Wakita D, Lane ME, Martinon D, Noval Rivas M, Luu M, Posadas EM, Crother TR, Arditi M. PMID: 32235862; PMCID: PMC7109066.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Autophagy Protects Against Developing Increased Lung Permeability and Hypoxemia by Down Regulating Inflammasome Activity and IL-1β in LPS Plus Mechanical Ventilation-Induced Acute Lung Injury. Front Immunol. 2020; 11:207.
Nosaka N, Martinon D, Moreira D, Crother TR, Arditi M, Shimada K. PMID: 32117318; PMCID: PMC7033480.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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A Comprehensive Update on Kawasaki Disease Vasculitis and Myocarditis. Curr Rheumatol Rep. 2020 02 05; 22(2):6.
Soni PR, Noval Rivas M, Arditi M. PMID: 32020498.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimals
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Interleukin-1 Beta-Mediated Sex Differences in Kawasaki Disease Vasculitis Development and Response to Treatment. Arterioscler Thromb Vasc Biol. 2020 03; 40(3):802-818.
Porritt RA, Markman JL, Maruyama D, Kocaturk B, Chen S, Lehman TJA, Lee Y, Fishbein MC, Noval Rivas M, Arditi M. PMID: 31996019; PMCID: PMC7047651.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation. Immunity. 2019 09 17; 51(3):508-521.e6.
Noval Rivas M, Wakita D, Franklin MK, Carvalho TT, Abolhesn A, Gomez AC, Fishbein MC, Chen S, Lehman TJ, Sato K, Shibuya A, Fasano A, Kiyono H, Abe M, Tatsumoto N, Yamashita M, Crother TR, Shimada K, Arditi M. PMID: 31471109; PMCID: PMC6751009.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
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Autophagy Limits Inflammasome During Chlamydia pneumoniae Infection. Front Immunol. 2019; 10:754.
Crother TR, Porritt RA, Dagvadorj J, Tumurkhuu G, Slepenkin AV, Peterson EM, Chen S, Shimada K, Arditi M. PMID: 31031755; PMCID: PMC6473188.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis. J Am Coll Cardiol. 2019 03 19; 73(10):1149-1169.
Onat UI, Yildirim AD, Tufanli Ö, Çimen I, Kocatürk B, Veli Z, Hamid SM, Shimada K, Chen S, Sin J, Shah PK, Gottlieb RA, Arditi M, Erbay E. PMID: 30871699; PMCID: PMC6424590.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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The Kawasaki Disease Comparative Effectiveness (KIDCARE) trial: A phase III, randomized trial of second intravenous immunoglobulin versus infliximab for resistant Kawasaki disease. Contemp Clin Trials. 2019 04; 79:98-103.
Roberts SC, Jain S, Tremoulet AH, Kim KK, Burns JC, KIDCARE Multicenter Study Group, Anand V, Anderson M, Ang J, Ansusinha E, Arditi M, Ashouri N, Bartlett A, Chatterjee A, DeBiasi R, Dekker C, DeZure C, Didion L, Dominguez S, El Feghaly R, Erdem G, Halasa N, Harahsheh A, Jackson MA, Jaggi P, Jain S, Jone PN, Kaushik N, Kurio G, Lillian A, Lloyd D, Manaloor J, McNelis A, Michalik DE, Newburger J, Newcomer C, Perkins T, Portman M, Romero J, Ronis T, Rowley A, Schneider K, Schuster J, Tejtel SKS, Sharma K, Simonsen K, Szmuszkovicz J, Truong D, Wood J, Yeh S. PMID: 30840903.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCTClinical Trials
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Young bone marrow transplantation preserves learning and memory in old mice. Commun Biol. 2019; 2:73.
Das MM, Godoy M, Chen S, Moser VA, Avalos P, Roxas KM, Dang I, Yáñez A, Zhang W, Bresee C, Arditi M, Liu GY, Svendsen CN, Goodridge HS. PMID: 30820468; PMCID: PMC6382867.
View in:
PubMed Mentions:
34 Translation:
Animals
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Myocardial fibrosis after adrenergic stimulation as a long-term sequela in a mouse model of Kawasaki disease vasculitis. JCI Insight. 2019 Feb 07; 4(3).
Matundan HH, Sin J, Rivas MN, Fishbein MC, Lehman TJ, Chen S, Gottlieb RA, Crother TR, Abe M, Arditi M. PMID: 30728329; PMCID: PMC6413776.
View in:
PubMed Mentions:
11 Fields:
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Quantification of Infectious Sendai Virus Using Plaque Assay. Bio Protoc. 2018 Nov 05; 8(21).
Tatsumoto N, Miyauchi T, Arditi M, Yamashita M. PMID: 30547053; PMCID: PMC6289198.
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PubMed Mentions:
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T-Cell-Intrinsic Receptor Interacting Protein 2 Regulates Pathogenic T Helper 17 Cell Differentiation. Immunity. 2018 11 20; 49(5):873-885.e7.
Shimada K, Porritt RA, Markman JL, O'Rourke JG, Wakita D, Noval Rivas M, Ogawa C, Kozhaya L, Martins GA, Unutmaz D, Baloh RH, Crother TR, Chen S, Arditi M. PMID: 30366765; PMCID: PMC6260980.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Sendai Virus Propagation Using Chicken Eggs. Bio Protoc. 2018 Sep 20; 8(18).
Tatsumoto N, Arditi M, Yamashita M. PMID: 30370318; PMCID: PMC6200407.
View in:
PubMed Mentions:
2
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Reply: Infection and Atherogenesis. J Am Coll Cardiol. 2018 08 21; 72(8):956.
Arditi M, Chen S, Shah PK. PMID: 30115238.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis. Cell Metab. 2018 09 04; 28(3):432-448.e4.
Tumurkhuu G, Dagvadorj J, Porritt RA, Crother TR, Shimada K, Tarling EJ, Erbay E, Arditi M, Chen S. PMID: 29937375; PMCID: PMC6125162.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Optimal tube length of orotracheal intubation for mice. Lab Anim. 2019 Feb; 53(1):79-83.
Nosaka N, Crother TR, Chen S, Arditi M, Shimada K. PMID: 29649932; PMCID: PMC6203655.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Chlamydia and Lipids Engage a Common Signaling Pathway That Promotes Atherogenesis. J Am Coll Cardiol. 2018 04 10; 71(14):1553-1570.
Chen S, Shimada K, Crother TR, Erbay E, Shah PK, Arditi M. PMID: 29622163; PMCID: PMC6042865.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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STOP the TRAFfic and Reduce the Plaque. J Am Coll Cardiol. 2018 02 06; 71(5):543-546.
Arditi M, Shah PK. PMID: 29406860.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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O-Acetylation of Peptidoglycan Limits Helper T Cell Priming and Permits Staphylococcus aureus Reinfection. Cell Host Microbe. 2017 Oct 11; 22(4):543-551.e4.
Sanchez M, Kolar SL, Müller S, Reyes CN, Wolf AJ, Ogawa C, Singhania R, De Carvalho DD, Arditi M, Underhill DM, Martins GA, Liu GY. PMID: 28943328; PMCID: PMC5679255.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis. Hum Mol Genet. 2017 07 15; 26(14):2719-2731.
Ehrhardt N, Doche ME, Chen S, Mao HZ, Walsh MT, Bedoya C, Guindi M, Xiong W, Ignatius Irudayam J, Iqbal J, Fuchs S, French SW, Mahmood Hussain M, Arditi M, Arumugaswami V, Péterfy M. PMID: 28449094; PMCID: PMC5886214.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Suppression of IL-12p70 formation by IL-2 or following macrophage depletion causes T-cell autoreactivity leading to CNS demyelination in HSV-1-infected mice. PLoS Pathog. 2017 May; 13(5):e1006401.
Lee DH, Zandian M, Kuo J, Mott KR, Chen S, Arditi M, Ghiasi H. PMID: 28542613; PMCID: PMC5456410.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Quercetin Inhibits Inflammasome Activation by Interfering with ASC Oligomerization and Prevents Interleukin-1 Mediated Mouse Vasculitis. Sci Rep. 2017 02 02; 7:41539.
Domiciano TP, Wakita D, Jones HD, Crother TR, Verri WA, Arditi M, Shimada K. PMID: 28148962; PMCID: PMC5288648.
View in:
PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Review: Found in Translation: International Initiatives Pursuing Interleukin-1 Blockade for Treatment of Acute Kawasaki Disease. Arthritis Rheumatol. 2017 02; 69(2):268-276.
Burns JC, Koné-Paut I, Kuijpers T, Shimizu C, Tremoulet A, Arditi M. PMID: 27792871; PMCID: PMC5274552.
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PubMed Mentions:
30 Fields:
Translation:
Humans
-
CD8+ T Cells Contribute to the Development of Coronary Arteritis in the Lactobacillus casei Cell Wall Extract-Induced Murine Model of Kawasaki Disease. Arthritis Rheumatol. 2017 Feb; 69(2):410-421.
Noval Rivas M, Lee Y, Wakita D, Chiba N, Dagvadorj J, Shimada K, Chen S, Fishbein MC, Lehman TJ, Crother TR, Arditi M. PMID: 27696768; PMCID: PMC5274597.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis. Sci Rep. 2016 12 20; 6:39257.
Haldar S, Dru C, Mishra R, Tripathi M, Duong F, Angara B, Fernandez A, Arditi M, Bhowmick NA. PMID: 27995963; PMCID: PMC5171776.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
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Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis. Circ Res. 2016 Sep 02; 119(6):e76-90.
Tumurkhuu G, Shimada K, Dagvadorj J, Crother TR, Zhang W, Luthringer D, Gottlieb RA, Chen S, Arditi M. PMID: 27384322; PMCID: PMC5010464.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
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Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. Cell. 2016 Jul 28; 166(3):624-636.
Wolf AJ, Reyes CN, Liang W, Becker C, Shimada K, Wheeler ML, Cho HC, Popescu NI, Coggeshall KM, Arditi M, Underhill DM. PMID: 27374331; PMCID: PMC5534359.
View in:
PubMed Mentions:
256 Fields:
Translation:
HumansAnimalsCells
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Immunological Consequences of Intestinal Fungal Dysbiosis. Cell Host Microbe. 2016 Jun 08; 19(6):865-73.
Wheeler ML, Limon JJ, Bar AS, Leal CA, Gargus M, Tang J, Brown J, Funari VA, Wang HL, Crother TR, Arditi M, Underhill DM, Iliev ID. PMID: 27237365; PMCID: PMC4900921.
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PubMed Mentions:
201 Fields:
Translation:
AnimalsCells
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Rationale and study design for a phase I/IIa trial of anakinra in children with Kawasaki disease and early coronary artery abnormalities (the ANAKID trial). Contemp Clin Trials. 2016 05; 48:70-5.
Tremoulet AH, Jain S, Kim S, Newburger J, Arditi M, Franco A, Best B, Burns JC. PMID: 27080929; PMCID: PMC5221485.
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PubMed Mentions:
30 Fields:
Translation:
HumansCTClinical Trials
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Role of Interleukin-1 Signaling in a Mouse Model of Kawasaki Disease-Associated Abdominal Aortic Aneurysm. Arterioscler Thromb Vasc Biol. 2016 05; 36(5):886-97.
Wakita D, Kurashima Y, Crother TR, Noval Rivas M, Lee Y, Chen S, Fury W, Bai Y, Wagner S, Li D, Lehman T, Fishbein MC, Hoffman HM, Shah PK, Shimada K, Arditi M. PMID: 26941015; PMCID: PMC4850105.
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PubMed Mentions:
53 Fields:
Translation:
HumansAnimalsCells
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Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan. Cell Host Microbe. 2015 Dec 09; 18(6):694-704.
Kolar SL, Kyme P, Tseng CW, Soliman A, Kaplan A, Liang J, Nizet V, Jiang D, Murali R, Arditi M, Underhill DM, Liu GY. PMID: 26651945; PMCID: PMC4683412.
View in:
PubMed Mentions:
35 Fields:
Translation:
Cells
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IL-1 Signaling Is Critically Required in Stromal Cells in Kawasaki Disease Vasculitis Mouse Model: Role of Both IL-1α and IL-1β. Arterioscler Thromb Vasc Biol. 2015 Dec; 35(12):2605-16.
Lee Y, Wakita D, Dagvadorj J, Shimada K, Chen S, Huang G, Lehman TJ, Fishbein MC, Hoffman HM, Crother TR, Arditi M. PMID: 26515418; PMCID: PMC4662607.
View in:
PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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TIR Domain-Containing Adapter-Inducing Beta Interferon (TRIF) Mediates Immunological Memory against Bacterial Pathogens. Infect Immun. 2015 Nov; 83(11):4404-15.
Kanagavelu S, Flores C, Termini JM, Romero L, Riveron R, Ruiz J, Arditi M, Schesser K, Fukata M. PMID: 26351279; PMCID: PMC4598391.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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POPsicle for Fever! Cooling Down the Inflammasome. Immunity. 2015 Aug 18; 43(2):213-5.
Shimada K, Crother TR, Arditi M. PMID: 26287676.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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TGF-β1 inhibits the production of IFN in response to CpG DNA via ubiquitination of TNF receptor-associated factor (TRAF) 6. Innate Immun. 2015 Oct; 21(7):770-7.
Naiki Y, Komatsu T, Koide N, Dagvadorj J, Yoshida T, Arditi M, Yokochi T. PMID: 26224488.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction. J Clin Invest. 2015 Aug 03; 125(8):3147-62.
de Couto G, Liu W, Tseliou E, Sun B, Makkar N, Kanazawa H, Arditi M, Marbán E. PMID: 26214527; PMCID: PMC4563759.
View in:
PubMed Mentions:
120 Fields:
Translation:
AnimalsCells
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Correction: Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One. 2015; 10(5):e0128735.
Jones HD, Yoo J, Crother TR, Kyme P, Ben-Shlomo A, Khalafi R, Tseng CW, Parks WC, Arditi M, Liu GY, Shimada K. PMID: 25996479; PMCID: PMC4440726.
View in:
PubMed Mentions:
3 Fields:
-
Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One. 2015; 10(4):e0123460.
Jones HD, Yoo J, Crother TR, Kyme P, Ben-Shlomo A, Khalafi R, Tseng CW, Parks WC, Arditi M, Liu GY, Shimada K. PMID: 25875775; PMCID: PMC4395431.
View in:
PubMed Mentions:
18 Fields:
Translation:
Animals
-
Lipopolysaccharide Induces Alveolar Macrophage Necrosis via CD14 and the P2X7 Receptor Leading to Interleukin-1α Release. Immunity. 2015 Apr 21; 42(4):640-53.
Dagvadorj J, Shimada K, Chen S, Jones HD, Tumurkhuu G, Zhang W, Wawrowsky KA, Crother TR, Arditi M. PMID: 25862090; PMCID: PMC4423803.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Mast cells play an important role in chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway. J Immunol. 2015 Apr 15; 194(8):3840-51.
Chiba N, Shimada K, Chen S, Jones HD, Alsabeh R, Slepenkin AV, Peterson E, Crother TR, Arditi M. PMID: 25754739; PMCID: PMC4390505.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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ApoB-100-related peptide vaccine protects against angiotensin II-induced aortic aneurysm formation and rupture. J Am Coll Cardiol. 2015 Feb 17; 65(6):546-56.
Honjo T, Chyu KY, Dimayuga PC, Yano J, Lio WM, Trinidad P, Zhao X, Zhou J, Chen S, Cercek B, Arditi M, Shah PK. PMID: 25677313.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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A single infection with Chlamydia pneumoniae is sufficient to exacerbate atherosclerosis in ApoE deficient mice. Cell Immunol. 2015 Mar; 294(1):25-32.
Sorrentino R, Yilmaz A, Schubert K, Crother TR, Pinto A, Shimada K, Arditi M, Chen S. PMID: 25666507; PMCID: PMC4391498.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Inflammation and pyroptosis mediate muscle expansion in an interleukin-1β (IL-1β)-dependent manner. J Biol Chem. 2015 Mar 06; 290(10):6574-83.
Haldar S, Dru C, Choudhury D, Mishra R, Fernandez A, Biondi S, Liu Z, Shimada K, Arditi M, Bhowmick NA. PMID: 25596528; PMCID: PMC4358290.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Alternatively spliced myeloid differentiation protein-2 inhibits TLR4-mediated lung inflammation. J Immunol. 2015 Feb 15; 194(4):1686-94.
Tumurkhuu G, Dagvadorj J, Jones HD, Chen S, Shimada K, Crother TR, Arditi M. PMID: 25576596; PMCID: PMC4323992.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury. Am J Respir Cell Mol Biol. 2014 Feb; 50(2):270-80.
Jones HD, Crother TR, Gonzalez-Villalobos RA, Jupelli M, Chen S, Dagvadorj J, Arditi M, Shimada K. PMID: 24007300; PMCID: PMC3930947.
View in:
PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Deficiency of CCAAT/enhancer binding protein-epsilon reduces atherosclerotic lesions in LDLR-/- mice. PLoS One. 2014; 9(1):e85341.
Okamoto R, Gery S, Gombart AF, Wang X, Castellani LW, Akagi T, Chen S, Arditi M, Ho Q, Lusis AJ, Li Q, Koeffler HP. PMID: 24489659; PMCID: PMC3904867.
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PubMed Mentions:
1 Fields:
Translation:
Animals
-
Chlamydia pneumoniae infection in mice induces chronic lung inflammation, iBALT formation, and fibrosis. PLoS One. 2013; 8(10):e77447.
Jupelli M, Shimada K, Chiba N, Slepenkin A, Alsabeh R, Jones HD, Peterson E, Chen S, Arditi M, Crother TR. PMID: 24204830; PMCID: PMC3808399.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Validation of a bedside, on-line/smartphone algorithm to differentiate Kawasaki Disease from other febrile illnesses. J Pediatr. 2013 May; 162(5):1077-9.
Arditi M. PMID: 23617976.
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PubMed Mentions: Fields:
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Plasmacytoid dendritic cells play a key role in tumor progression in lipopolysaccharide-stimulated lung tumor-bearing mice. J Immunol. 2013 Mar 01; 190(5):2391-402.
Rega A, Terlizzi M, Luciano A, Forte G, Crother TR, Arra C, Arditi M, Pinto A, Sorrentino R. PMID: 23355734.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease. EMBO Mol Med. 2013 Feb; 5(2):210-20.
Kentsis A, Shulman A, Ahmed S, Brennan E, Monuteaux MC, Lee YH, Lipsett S, Paulo JA, Dedeoglu F, Fuhlbrigge R, Bachur R, Bradwin G, Arditi M, Sundel RP, Newburger JW, Steen H, Kim S. PMID: 23281308; PMCID: PMC3569638.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Plasmacytoid dendritic cells play a role for effective innate immune responses during Chlamydia pneumoniae infection in mice. PLoS One. 2012; 7(10):e48655.
Crother TR, Ma J, Jupelli M, Chiba N, Chen S, Slepenkin A, Alsabeh R, Peterson E, Shimada K, Arditi M. PMID: 23119083; PMCID: PMC3485374.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Regulation of Toll-like receptor 2 interaction with Ecgp96 controls Escherichia coli K1 invasion of brain endothelial cells. Cell Microbiol. 2013 Jan; 15(1):63-81.
Krishnan S, Chen S, Turcatel G, Arditi M, Prasadarao NV. PMID: 22963587; PMCID: PMC3524395.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Innate immune responses to Chlamydia pneumoniae infection: role of TLRs, NLRs, and the inflammasome. Microbes Infect. 2012 Nov; 14(14):1301-7.
Shimada K, Crother TR, Arditi M. PMID: 22985781; PMCID: PMC3511600.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Marked acceleration of atherosclerosis after Lactobacillus casei-induced coronary arteritis in a mouse model of Kawasaki disease. Arterioscler Thromb Vasc Biol. 2012 Aug; 32(8):e60-71.
Chen S, Lee Y, Crother TR, Fishbein M, Zhang W, Yilmaz A, Shimada K, Schulte DJ, Lehman TJ, Shah PK, Arditi M. PMID: 22628430; PMCID: PMC3480341.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Interleukin-1β is crucial for the induction of coronary artery inflammation in a mouse model of Kawasaki disease. Circulation. 2012 Mar 27; 125(12):1542-50.
Lee Y, Schulte DJ, Shimada K, Chen S, Crother TR, Chiba N, Fishbein MC, Lehman TJ, Arditi M. PMID: 22361326; PMCID: PMC3337219.
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PubMed Mentions:
99 Fields:
Translation:
HumansAnimalsCells
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Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity. 2012 Mar 23; 36(3):401-14.
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, Underhill DM, Town T, Arditi M. PMID: 22342844; PMCID: PMC3312986.
View in:
PubMed Mentions:
949 Fields:
Translation:
AnimalsCells
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Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria. J Immunol. 2011 Dec 01; 187(11):6002-10.
Wolf AJ, Arruda A, Reyes CN, Kaplan AT, Shimada T, Shimada K, Arditi M, Liu G, Underhill DM. PMID: 22031762; PMCID: PMC3221871.
View in:
PubMed Mentions:
45 Fields:
Translation:
AnimalsCells
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Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection. J Infect Dis. 2012 Jan 01; 205(1):152-61.
Divanovic S, Sawtell NM, Trompette A, Warning JI, Dias A, Cooper AM, Yap GS, Arditi M, Shimada K, Duhadaway JB, Prendergast GC, Basaraba RJ, Mellor AL, Munn DH, Aliberti J, Karp CL. PMID: 21990421; PMCID: PMC3242739.
View in:
PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway. J Immunol. 2011 Oct 15; 187(8):4331-7.
Gray P, Dagvadorj J, Michelsen KS, Brikos C, Rentsendorj A, Town T, Crother TR, Arditi M. PMID: 21918188; PMCID: PMC3186846.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. PLoS One. 2011; 6(6):e21477.
Shimada K, Crother TR, Karlin J, Chen S, Chiba N, Ramanujan VK, Vergnes L, Ojcius DM, Arditi M. PMID: 21731762; PMCID: PMC3121765.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansAnimalsCells
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Chlamydia pneumoniae infection induced allergic airway sensitization is controlled by regulatory T-cells and plasmacytoid dendritic cells. PLoS One. 2011; 6(6):e20784.
Crother TR, Schröder NW, Karlin J, Chen S, Shimada K, Slepenkin A, Alsabeh R, Peterson E, Arditi M. PMID: 21695198; PMCID: PMC3112152.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Macrophage IL-12p70 signaling prevents HSV-1-induced CNS autoimmunity triggered by autoaggressive CD4+ Tregs. Invest Ophthalmol Vis Sci. 2011 Apr; 52(5):2321-33.
Mott KR, Gate D, Zandian M, Allen SJ, Rajasagi NK, van Rooijen N, Chen S, Arditi M, Rouse BT, Flavell RA, Town T, Ghiasi H. PMID: 21220560; PMCID: PMC3080735.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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IL-2 suppression of IL-12p70 by a recombinant HSV-1 expressing IL-2 induces T-cell auto-reactivity and CNS demyelination. PLoS One. 2011 Feb 18; 6(2):e16820.
Zandian M, Mott KR, Allen SJ, Chen S, Arditi M, Ghiasi H. PMID: 21364747; PMCID: PMC3041759.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis. PLoS One. 2010 Oct 15; 5(10):e15044.
Soliman A, Michelsen KS, Karahashi H, Lu J, Meng FJ, Qu X, Crother TR, Rabizadeh S, Chen S, Caplan MS, Arditi M, Jilling T. PMID: 20976181; PMCID: PMC2955554.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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IL-17A is proatherogenic in high-fat diet-induced and Chlamydia pneumoniae infection-accelerated atherosclerosis in mice. J Immunol. 2010 Nov 01; 185(9):5619-27.
Chen S, Shimada K, Zhang W, Huang G, Crother TR, Arditi M. PMID: 20935201; PMCID: PMC3046880.
View in:
PubMed Mentions:
62 Fields:
Translation:
AnimalsCells
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Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer. PLoS One. 2010 Sep 27; 5(9):e13027.
Lowe EL, Crother TR, Rabizadeh S, Hu B, Wang H, Chen S, Shimada K, Wong MH, Michelsen KS, Arditi M. PMID: 20885960; PMCID: PMC2946405.
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PubMed Mentions:
74 Fields:
Translation:
HumansAnimalsCells
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Plasmacytoid dendritic cells alter the antitumor activity of CpG-oligodeoxynucleotides in a mouse model of lung carcinoma. J Immunol. 2010 Oct 15; 185(8):4641-50.
Sorrentino R, Morello S, Luciano A, Crother TR, Maiolino P, Bonavita E, Arra C, Adcock IM, Arditi M, Pinto A. PMID: 20855872.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Emerging role of IL-17 in atherosclerosis. J Innate Immun. 2010; 2(4):325-33.
Chen S, Crother TR, Arditi M. PMID: 20505315; PMCID: PMC2895754.
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PubMed Mentions:
37 Fields:
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HumansAnimalsCells
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Identification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signaling. J Immunol. 2010 Jun 01; 184(11):6359-66.
Gray P, Michelsen KS, Sirois CM, Lowe E, Shimada K, Crother TR, Chen S, Brikos C, Bulut Y, Latz E, Underhill D, Arditi M. PMID: 20435923; PMCID: PMC3057206.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Plasmacytoid dendritic cells modulate nonprotective T-cell responses to genital infection by Chlamydia muridarum. FEMS Immunol Med Microbiol. 2010 Apr; 58(3):397-404.
Moniz RJ, Chan AM, Gordon LK, Braun J, Arditi M, Kelly KA. PMID: 20180848; PMCID: PMC3153358.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Plasmacytoid dendritic cells prevent cigarette smoke and Chlamydophila pneumoniae-induced Th2 inflammatory responses. Am J Respir Cell Mol Biol. 2010 Oct; 43(4):422-31.
Sorrentino R, Gray P, Chen S, Shimada K, Crother TR, Arditi M. PMID: 19901344; PMCID: PMC2951872.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Involvement of innate and adaptive immunity in a murine model of coronary arteritis mimicking Kawasaki disease. J Immunol. 2009 Oct 15; 183(8):5311-8.
Schulte DJ, Yilmaz A, Shimada K, Fishbein MC, Lowe EL, Chen S, Wong M, Doherty TM, Lehman T, Crother TR, Sorrentino R, Arditi M. PMID: 19786535; PMCID: PMC3031986.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLoS One. 2009 Jul 27; 4(7):e6387.
Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, Liu GY. PMID: 19633710; PMCID: PMC2711303.
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PubMed Mentions:
52 Fields:
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AnimalsCells
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Lipopolysaccharide-induced apoptosis in transformed bovine brain endothelial cells and human dermal microvessel endothelial cells: the role of JNK. J Immunol. 2009 Jun 01; 182(11):7280-6.
Karahashi H, Michelsen KS, Arditi M. PMID: 19454725; PMCID: PMC3057198.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Chlamydial heat shock protein 60 induces acute pulmonary inflammation in mice via the Toll-like receptor 4- and MyD88-dependent pathway. Infect Immun. 2009 Jul; 77(7):2683-90.
Bulut Y, Shimada K, Wong MH, Chen S, Gray P, Alsabeh R, Doherty TM, Crother TR, Arditi M. PMID: 19398543; PMCID: PMC2708574.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection. PLoS Pathog. 2009 Apr; 5(4):e1000379.
Shimada K, Chen S, Dempsey PW, Sorrentino R, Alsabeh R, Slepenkin AV, Peterson E, Doherty TM, Underhill D, Crother TR, Arditi M. PMID: 19360122; PMCID: PMC2660273.
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PubMed Mentions:
85 Fields:
Translation:
AnimalsCells
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Giant cell arteritis: dendritic cells take two T's to tango. Circ Res. 2009 Feb 27; 104(4):425-7.
Yilmaz A, Arditi M. PMID: 19246686; PMCID: PMC3176683.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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HMGB1 mediates endogenous TLR2 activation and brain tumor regression. PLoS Med. 2009 Jan 13; 6(1):e10.
Curtin JF, Liu N, Candolfi M, Xiong W, Assi H, Yagiz K, Edwards MR, Michelsen KS, Kroeger KM, Liu C, Muhammad AK, Clark MC, Arditi M, Comin-Anduix B, Ribas A, Lowenstein PR, Castro MG. PMID: 19143470; PMCID: PMC2621261.
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PubMed Mentions:
201 Fields:
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HumansAnimalsCells
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Innate immunity, Toll-like receptors, and atherosclerosis: mouse models and methods. Methods Mol Biol. 2009; 517:381-99.
Sorrentino R, Arditi M. PMID: 19378021.
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PubMed Mentions:
5 Fields:
Translation:
Animals
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Resident enteric microbiota and CD8+ T cells shape the abundance of marginal zone B cells. Eur J Immunol. 2008 Dec; 38(12):3411-25.
Wei B, Su TT, Dalwadi H, Stephan RP, Fujiwara D, Huang TT, Brewer S, Chen L, Arditi M, Borneman J, Rawlings DJ, Braun J. PMID: 19009526; PMCID: PMC2734463.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis. J Immunol. 2008 Nov 15; 181(10):7176-85.
Naiki Y, Sorrentino R, Wong MH, Michelsen KS, Shimada K, Chen S, Yilmaz A, Slepenkin A, Schröder NW, Crother TR, Bulut Y, Doherty TM, Bradley M, Shaposhnik Z, Peterson EM, Tontonoz P, Shah PK, Arditi M. PMID: 18981139; PMCID: PMC2683843.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation. J Immunol. 2008 Nov 15; 181(10):7186-93.
Chen S, Sorrentino R, Shimada K, Bulut Y, Doherty TM, Crother TR, Arditi M. PMID: 18981140; PMCID: PMC2662697.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Innate immune responses during respiratory tract infection with a bacterial pathogen induce allergic airway sensitization. J Allergy Clin Immunol. 2008 Sep; 122(3):595-602.e5.
Schröder NW, Crother TR, Naiki Y, Chen S, Wong MH, Yilmaz A, Slepenkin A, Schulte D, Alsabeh R, Doherty TM, Peterson E, Nel AE, Arditi M. PMID: 18774395; PMCID: PMC3052793.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Villous B cells of the small intestine are specialized for invariant NK T cell dependence. J Immunol. 2008 Apr 01; 180(7):4629-38.
Velázquez P, Wei B, McPherson M, Mendoza LM, Nguyen SL, Turovskaya O, Kronenberg M, Huang TT, Schrage M, Lobato LN, Fujiwara D, Brewer S, Arditi M, Cheng G, Sartor RB, Newberry RD, Braun J. PMID: 18354186; PMCID: PMC2683842.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Activated myeloid dendritic cells accumulate and co-localize with CD3+ T cells in coronary artery lesions in patients with Kawasaki disease. Exp Mol Pathol. 2007 Aug; 83(1):93-103.
Yilmaz A, Rowley A, Schulte DJ, Doherty TM, Schröder NW, Fishbein MC, Kalelkar M, Cicha I, Schubert K, Daniel WG, Garlichs CD, Arditi M. PMID: 17335804.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
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The role of innate immunity in the pathogenesis of asthma: evidence for the involvement of Toll-like receptor signaling. J Endotoxin Res. 2007; 13(5):305-12.
Schröder NW, Arditi M. PMID: 17986489.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Toll-like receptors and innate immunity in gut homeostasis and pathology. Curr Opin Hematol. 2007 Jan; 14(1):48-54.
Michelsen KS, Arditi M. PMID: 17133100.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
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Differential expression of Toll-like receptor 2 (TLR2) and responses to TLR2 ligands between human and murine vascular endothelial cells. J Endotoxin Res. 2007; 13(5):281-96.
Wong MH, Schulte DJ, Arditi M, Michelsen KS. PMID: 17986487.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine. Gastroenterology. 2006 Sep; 131(3):862-77.
Fukata M, Chen A, Klepper A, Krishnareddy S, Vamadevan AS, Thomas LS, Xu R, Inoue H, Arditi M, Dannenberg AJ, Abreu MT. PMID: 16952555; PMCID: PMC2169292.
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PubMed Mentions:
197 Fields:
Translation:
HumansAnimalsCells
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The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis. J Immunol. 2006 Sep 01; 177(5):3273-82.
Jilling T, Simon D, Lu J, Meng FJ, Li D, Schy R, Thomson RB, Soliman A, Arditi M, Caplan MS. PMID: 16920968; PMCID: PMC2697969.
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PubMed Mentions:
202 Fields:
Translation:
AnimalsCells
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Chlamydia heat shock protein 60 induces trophoblast apoptosis through TLR4. J Immunol. 2006 Jul 15; 177(2):1257-63.
Equils O, Lu D, Gatter M, Witkin SS, Bertolotto C, Arditi M, McGregor JA, Simmons CF, Hobel CJ. PMID: 16818785.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling. J Immunol. 2006 Jul 01; 177(1):322-32.
Rallabhandi P, Bell J, Boukhvalova MS, Medvedev A, Lorenz E, Arditi M, Hemming VG, Blanco JC, Segal DM, Vogel SN. PMID: 16785528.
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PubMed Mentions:
98 Fields:
Translation:
HumansCells
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Toll-like receptor signaling and atherosclerosis. Curr Opin Hematol. 2006 May; 13(3):163-8.
Michelsen KS, Arditi M. PMID: 16567960.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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TLR signaling and trapped vascular dendritic cells in the development of atherosclerosis. Trends Immunol. 2006 May; 27(5):222-7.
Doherty TM, Fisher EA, Arditi M. PMID: 16580258.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Ubiquitination and de-ubiquitination: role in regulation of signaling by Toll-like receptors. J Endotoxin Res. 2006; 12(6):337-45.
Lowe EL, Doherty TM, Karahashi H, Arditi M. PMID: 17254387.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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TLR2 and MyD88 contribute to Lactobacillus casei extract-induced focal coronary arteritis in a mouse model of Kawasaki disease. Circulation. 2005 Nov 08; 112(19):2966-73.
Rosenkranz ME, Schulte DJ, Agle LM, Wong MH, Zhang W, Ivashkiv L, Doherty TM, Fishbein MC, Lehman TJ, Michelsen KS, Arditi M. PMID: 16275884.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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Blood-brain barrier invasion by group B Streptococcus depends upon proper cell-surface anchoring of lipoteichoic acid. J Clin Invest. 2005 Sep; 115(9):2499-507.
Doran KS, Engelson EJ, Khosravi A, Maisey HC, Fedtke I, Equils O, Michelsen KS, Arditi M, Peschel A, Nizet V. PMID: 16138192; PMCID: PMC1193870.
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PubMed Mentions:
119 Fields:
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HumansAnimalsCells
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Innate immunity, Toll-like receptors and host response to infection. Pediatr Infect Dis J. 2005 Jul; 24(7):643-4.
Doherty TM, Arditi M. PMID: 15999009.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia. J Biol Chem. 2005 Aug 12; 280(32):29242-9.
Naiki Y, Michelsen KS, Schröder NW, Alsabeh R, Slepenkin A, Zhang W, Chen S, Wei B, Bulut Y, Wong MH, Peterson EM, Arditi M. PMID: 15964841.
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PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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Lipopolysaccharide, toll-like receptors, and the immune contribution to atherosclerosis. Arterioscler Thromb Vasc Biol. 2005 May; 25(5):e38; author reply e38-9.
Doherty TM, Shah PK, Arditi M. PMID: 15863713.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis. Am J Physiol Gastrointest Liver Physiol. 2005 May; 288(5):G1055-65.
Fukata M, Michelsen KS, Eri R, Thomas LS, Hu B, Lukasek K, Nast CC, Lechago J, Xu R, Naiki Y, Soliman A, Arditi M, Abreu MT. PMID: 15826931.
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PubMed Mentions:
228 Fields:
Translation:
AnimalsCells
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TLR signaling in the gut in health and disease. J Immunol. 2005 Apr 15; 174(8):4453-60.
Abreu MT, Fukata M, Arditi M. PMID: 15814663.
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PubMed Mentions:
203 Fields:
Translation:
HumansCells
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Mycobacterium tuberculosis heat shock proteins use diverse Toll-like receptor pathways to activate pro-inflammatory signals. J Biol Chem. 2005 Jun 03; 280(22):20961-7.
Bulut Y, Michelsen KS, Hayrapetian L, Naiki Y, Spallek R, Singh M, Arditi M. PMID: 15809303.
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PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
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Mastoparan, a G protein agonist peptide, differentially modulates TLR4- and TLR2-mediated signaling in human endothelial cells and murine macrophages. J Immunol. 2005 Apr 01; 174(7):4252-61.
Lentschat A, Karahashi H, Michelsen KS, Thomas LS, Zhang W, Vogel SN, Arditi M. PMID: 15778388.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling. J Biol Chem. 2005 Feb 18; 280(7):5491-5.
Naiki Y, Michelsen KS, Zhang W, Chen S, Doherty TM, Arditi M. PMID: 15623538.
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PubMed Mentions:
65 Fields:
Translation:
HumansCells
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Role of Toll-like receptors in atherosclerosis. Circ Res. 2004 Dec 10; 95(12):e96-7.
Michelsen KS, Doherty TM, Shah PK, Arditi M. PMID: 15591233.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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TB, or not TB: that is the question -- does TLR signaling hold the answer? J Clin Invest. 2004 Dec; 114(12):1699-703.
Doherty TM, Arditi M. PMID: 15599394; PMCID: PMC535076.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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TLR signaling: an emerging bridge from innate immunity to atherogenesis. J Immunol. 2004 Nov 15; 173(10):5901-7.
Michelsen KS, Doherty TM, Shah PK, Arditi M. PMID: 15528321.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Beta-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells. J Immunol. 2004 Nov 01; 173(9):5398-405.
Vora P, Youdim A, Thomas LS, Fukata M, Tesfay SY, Lukasek K, Michelsen KS, Wada A, Hirayama T, Arditi M, Abreu MT. PMID: 15494486.
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PubMed Mentions:
121 Fields:
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HumansAnimalsCells
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Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc Natl Acad Sci U S A. 2004 Jul 20; 101(29):10679-84.
Michelsen KS, Wong MH, Shah PK, Zhang W, Yano J, Doherty TM, Akira S, Rajavashisth TB, Arditi M. PMID: 15249654; PMCID: PMC489994.
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PubMed Mentions:
421 Fields:
Translation:
HumansAnimalsCells
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Innate immunity and toll-like receptors: clinical implications of basic science research. J Pediatr. 2004 Apr; 144(4):421-9.
Abreu MT, Arditi M. PMID: 15069387.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections. J Exp Med. 2003 Aug 18; 198(4):521-31.
Medvedev AE, Lentschat A, Kuhns DB, Blanco JC, Salkowski C, Zhang S, Arditi M, Gallin JI, Vogel SN. PMID: 12925671; PMCID: PMC2194174.
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PubMed Mentions:
72 Fields:
Translation:
HumansCells
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Toll-like receptor 2 (TLR2) and TLR9 signaling results in HIV-long terminal repeat trans-activation and HIV replication in HIV-1 transgenic mouse spleen cells: implications of simultaneous activation of TLRs on HIV replication. J Immunol. 2003 May 15; 170(10):5159-64.
Equils O, Schito ML, Karahashi H, Madak Z, Yarali A, Michelsen KS, Sher A, Arditi M. PMID: 12734363.
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PubMed Mentions:
45 Fields:
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HumansAnimalsCells
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Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut. J Immunol. 2003 Feb 01; 170(3):1406-15.
Melmed G, Thomas LS, Lee N, Tesfay SY, Lukasek K, Michelsen KS, Zhou Y, Hu B, Arditi M, Abreu MT. PMID: 12538701.
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PubMed Mentions:
147 Fields:
Translation:
HumansCells
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TLR signaling at the intestinal epithelial interface. J Endotoxin Res. 2003; 9(5):322-30.
Abreu MT, Thomas LS, Arnold ET, Lukasek K, Michelsen KS, Arditi M. PMID: 14577850.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells. J Biol Chem. 2002 Jun 07; 277(23):20431-7.
Abreu MT, Arnold ET, Thomas LS, Gonsky R, Zhou Y, Hu B, Arditi M. PMID: 11923281.
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PubMed Mentions:
111 Fields:
Translation:
HumansCells
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Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J Immunol. 2002 Feb 01; 168(3):1435-40.
Bulut Y, Faure E, Thomas L, Karahashi H, Michelsen KS, Equils O, Morrison SG, Morrison RP, Arditi M. PMID: 11801686.