Ellen B Klapper

Title(s)Hs Clinical Professor, Pathology and Laboratory Medicine
SchoolMedicine
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    1. The seasonal distribution of immune thrombotic thrombocytopenic purpura is influenced by geography: Epidemiologic findings from a multi-center analysis of 719 disease episodes. Am J Hematol. 2024 Nov; 99(11):2063-2074. Jacobs JW, Stanek CG, Booth GS, Symeonidis A, Shih AW, Allen ES, Gavriilaki E, Grossman BJ, Pavenski K, Moorehead A, Peyvandi F, Agosti P, Mancini I, Stephens LD, Raval JS, Mingot-Castellano ME, Crowe EP, Daou L, Pai M, Arnold DM, Marques MB, Henrie R, Smith TW, Sreenivasan G, Siniard RC, Wallace LR, Yamada C, Duque MA, Wu Y, Harrington TJ, Byrnes DM, Bitsani A, Davis AK, Robinson DH, Eichbaum Q, Figueroa Villalba CA, Juskewitch JE, Kaiafa G, Kapsali E, Klapper E, Perez-Alvarez I, Klein MS, Kotsiou N, Lalayanni C, Mandala E, Aldarweesh F, Alkhateb R, Fortuny L, Mellios Z, Papalexandri A, Parsons MG, Schlueter AJ, Tormey CA, Wellard C, Wood EM, Jia S, Wheeler AP, Powers AA, Webb CB, Yates SG, Bouzid R, Coppo P, Bloch EM, Adkins BD. PMID: 39136282.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Reconsidering Fresh Frozen Plasma Availability to Reduce Blood Product Waste During Massive Transfusion Events in Trauma. Am Surg. 2024 Oct; 90(10):2530-2533. Shen A, Di Meo B, Perez IA, Hashim Y, Ko A, Margulies DR, Klapper EB, Barmparas G. PMID: 38658467.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    3. Correction to: Amanita Mushroom Toxin Poisoning in Los Angeles County. ACG Case Rep J. 2024 Mar; 11(3):e01304. Jobin PG, Stewart C, Vipani A, Perez-Alvarez I, Pepkowitz S, Klapper E, Berg A, Stillman K, Torbati S, Kuo A, Trivedi H, Yang JD, Steinberger J, Van Allan RJ, Friedman O, Cardoza K, Ayoub WS. PMID: 38524265; PMCID: PMC10959558.
      View in: PubMed   Mentions:
    4. Amanita Mushroom Toxin Poisoning in Los Angeles County. ACG Case Rep J. 2024 Jan; 11(1):e01246. Jobin PG, Stewart C, Vipani A, Perez-Alvarez I, Pepkowitz S, Klapper E, Berg A, Stillman K, Torbati S, Kuo A, Trivedi H, Yang JD, Steinberger J, Van Allan RJ, Friedman O, Cardoza K, Ayoub WS. PMID: 38162005; PMCID: PMC10754582.
      View in: PubMed   Mentions:
    5. Durable remission of thrombotic thrombocytopenic purpura in the setting of pembrolizumab therapy. Transfusion. 2023 06; 63(6):1241-1245. Kozak M, Rubenstein W, Okwan-Duodu D, Friedman K, Nassir Y, Perez-Alvarez I, Gibb DR, Klapper E, Pepkowitz S. PMID: 37096845.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Successful autologous hematopoietic stem cell transplants using Salmonella positive products collected from asymptomatic donors. Transfusion. 2023 04; 63(4):861-866. Phou S, Perez-Alvarez I, Morgan M, Contreras DA, Ben-Aderet M, Gaddam E, Paquette R, Vescio R, Pepkowitz SH, Gibb DR, Zabner R, Klapper EB. PMID: 36880384.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Blood Type A1 Mismatch Does Not Affect Heart Transplant Outcomes at One Year. J Clin Med. 2023 Feb 08; 12(4). Cao L, Kim S, Klapper E, Kobashigawa JA, Kittleson MM. PMID: 36835873; PMCID: PMC9961239.
      View in: PubMed   Mentions:
    8. Prior vaccination has changed the composition of the COVID-19 convalescent plasma inventory. Transfusion. 2022 10; 62(10):2153-2154. Pepkowitz SH, Gibb D, Perez-Alvarez I, Phou S, Tanaka J, Rojo J, Klapper E. PMID: 36214574; PMCID: PMC9874893.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    9. Investigating anti-D in an individual with the weak D type 2 genotype. Immunohematology. 2022 Sep 01; 38(3):77-81. Phou S, Nguyen N, Revilla J, Rodberg K, Gibb DR, Pepkowitz SH, Klapper EB. PMID: 36190200.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Overtransfusion of packed red blood cells during massive transfusion activation: a potential quality metric for trauma resuscitation. Trauma Surg Acute Care Open. 2022; 7(1):e000896. Barmparas G, Huang R, Lee WG, Hashim YM, Pepkowitz SH, Klapper EB, Margulies DR. PMID: 35979038; PMCID: PMC9330347.
      View in: PubMed   Mentions:
    11. The feasibility of multiple units of convalescent plasma in mechanically ventilated patients with COVID-19: A pilot study. Transfus Apher Sci. 2022 08; 61(4):103423. Merin NM, LeVee AA, Merlo CA, Spector K, Coleman H, Klapper E, Hayes C, Zabner R, McDyer JF, Eby YJ, Sullivan DJ, Tobian AAR, Bloch EM, Hager DN. PMID: 35337753; PMCID: PMC8923025.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Implementation of a low-titer stored whole blood transfusion program for civilian trauma patients: Early experience and logistical challenges. Injury. 2022 May; 53(5):1576-1580. Barmparas G, Huang R, Hayes C, Pepkowitz SH, Abumuhor IA, Thomasian SE, Margulies DR, Klapper EB. PMID: 35123798.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Too lean: Time to build back true resiliency in the national blood supply. Transfusion. 2021 09; 61(9):2768-2771. Barnhard S, Klapper E, Kopko P, Tran MH, Ziman A, University of California Transfusion Medicine Physicians. PMID: 34331464.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    14. Altered type 1 interferon responses in alloimmunized and nonalloimmunized patients with sickle cell disease. EJHaem. 2021 Nov; 2(4):700-710. Madany E, Lee J, Halprin C, Seo J, Baca N, Majlessipour F, Hendrickson JE, Pepkowitz SH, Hayes C, Klapper E, Gibb DR. PMID: 35128535; PMCID: PMC8813163.
      View in: PubMed   Mentions: 4  
    15. Recipient and surgical factors trigger severe primary graft dysfunction after heart transplant. J Heart Lung Transplant. 2021 09; 40(9):970-980. Benck L, Kransdorf EP, Emerson DA, Rushakoff J, Kittleson MM, Klapper EB, Megna DJ, Esmailian F, Halprin C, Trento A, Ramzy D, Czer LSC, Chang DH, Ebinger JE, Kobashigawa JA, Patel JK. PMID: 34272125.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Blood group O convalescent plasma donations have significantly lower levels of SARS-CoV-2 IgG antibodies compared to blood group A donations. Transfusion. 2021 08; 61(8):2245-2249. Hayes C, Rubenstein W, Gibb D, Klapper E, Tanaka J, Pepkowitz S. PMID: 34036595; PMCID: PMC8242504.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    17. SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus. Commun Biol. 2021 01 29; 4(1):129. Dogan M, Kozhaya L, Placek L, Gunter C, Yigit M, Hardy R, Plassmeyer M, Coatney P, Lillard K, Bukhari Z, Kleinberg M, Hayes C, Arditi M, Klapper E, Merin N, Liang BT, Gupta R, Alpan O, Unutmaz D. PMID: 33514825; PMCID: PMC7846565.
      View in: PubMed   Mentions: 65  Translation:HumansCells
    18. Novel SARS-CoV-2 specific antibody and neutralization assays reveal wide range of humoral immune response during COVID-19. medRxiv. 2020 Oct 14. Dogan M, Kozhaya L, Placek L, Gunter CL, Yigit M, Hardy R, Plassmeyer M, Coatney P, Lillard K, Bukhari Z, Kleinberg M, Hayes C, Arditi M, Klapper E, Merin N, Liang BT, Gupta R, Alpan O, Unutmaz D. PMID: 32676617; PMCID: PMC7359542.
      View in: PubMed   Mentions:
    19. Comparison of the platelet activation status of single-donor platelets obtained with two different cell separator technologies. Transfusion. 2020 09; 60(9):2067-2078. Millar D, Hayes C, Jones J, Klapper E, Kniep JN, Luu HS, Noland DK, Petitti L, Poisson JL, Spaepen E, Ye Z, Maurer-Spurej E. PMID: 32729161.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    20. Probable transfusion transmission of West Nile virus from an apheresis platelet that screened non-reactive by individual donor-nucleic acid testing. Transfusion. 2020 02; 60(2):424-429. Hayes C, Stephens L, Fridey JL, Snyder RE, Groves JA, Stramer SL, Klapper E. PMID: 31633814.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    21. Critical developments of 2018: A review of the literature from selected topics in transfusion. A committee report from the AABB's Clinical Transfusion Medicine Committee. Transfusion. 2019 08; 59(8):2733-2748. Cohn CS, Allen ES, Cushing MM, Dunbar NM, Friedman DF, Goel R, Harm SK, Heddle N, Hopkins CK, Klapper E, Perumbeti A, Ramsey G, Raval JS, Schwartz J, Shaz BH, Spinella PC, Pagano MB. PMID: 31148175.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    22. RHD genotyping of serologic RhD-negative blood donors in a hospital-based blood donor center. Transfusion. 2019 07; 59(7):2422-2428. Perez-Alvarez I, Hayes C, Hailemariam T, Shin E, Hutchinson T, Klapper E. PMID: 31059639.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Neuroinvasive West Nile Virus Post-Heart Transplantation: A Case Report. Transplant Proc. 2018 Dec; 50(10):4057-4061. Dong E, Morris K, Sodhi G, Chang D, Czer L, Chung J, Zabner R, Raastad K, Klapper E, Kobashigawa J, Nurok M. PMID: 30577314.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    24. Cefotetan-Induced Hemolytic Anemia: Case Series and Review. J Pharm Pract. 2019 Dec; 32(6):679-682. Lim K, Tran H, Hirai-Yang A, Vakil N, Marks G, Klapper E. PMID: 30189781.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Critical developments of 2017: a review of the literature from selected topics in transfusion. A committee report from the AABB Clinical Transfusion Medicine Committee. Transfusion. 2018 04; 58(4):1065-1075. Cushing MM, Kelley J, Klapper E, Friedman DF, Goel R, Heddle NM, Hopkins CK, Karp JK, Pagano MB, Perumbeti A, Ramsey G, Roback JD, Schwartz J, Shaz BH, Spinella PC, Cohn CS, Cohn CS, Cushing MM, Kelley J, Klapper E. PMID: 29520794.
      View in: PubMed   Mentions: 3     Fields:    
    26. Molecular immunohaematology round table discussions at the AABB Annual Meeting, Orlando 2016. Blood Transfus. 2018 09; 16(5):447-456. Flegel WA, Chen Q, Castilho L, Keller MA, Klapper EB, Lane WJ, Pirenne F, Stack G, St-Louis M, Tormey CA, Waxman DA, Weinstock C, Wendel S, Denomme GA. PMID: 29517973; PMCID: PMC6125235.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Multi-Center Evaluation of the Automated Immunohematology Instrument, the ORTHO VISION Analyzer. Lab Med. 2017 Feb; 48(1):29-38. Aysola A, Wheeler L, Brown R, Denham R, Colavecchia C, Pavenski K, Krok E, Hayes C, Klapper E. PMID: 28138088.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Molecular immunohaematology round table discussions at the AABB Annual Meeting, Anaheim 2015. Blood Transfus. 2016 11; 14(6):557-565. Flegel WA, Castilho L, Heaton WA, Keller MA, Klapper EB, Lane WJ, Pirenne F, Shehata N, Stack G, St-Louis M, Tormey CA, Wagner FF, Waxman DA, Denomme GA. PMID: 27483480; PMCID: PMC5111385.
      View in: PubMed   Mentions: 3     Fields:    
    29. Molecular immunohaematology round table discussions at the AABB Annual Meeting, Philadelphia 2014. Blood Transfus. 2016 09; 14(5):425-33. Flegel WA, De Castilho SL, Keller MA, Klapper EB, Moulds JM, Noizat-Pirenne F, Shehata N, Stack G, St-Louis M, Tormey CA, Waxman DA, Weinstock C, Wendel S, Denomme GA. PMID: 26710354; PMCID: PMC5016302.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    30. Successful reduction of plasma free-hemoglobin using therapeutic plasma exchange: A case report. Transfus Apher Sci. 2016 Apr; 54(2):253-5. Hayes C, Shafi H, Mason H, Klapper E. PMID: 26388049.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    31. Extracorporeal photopheresis in heart transplant rejection. Transfus Apher Sci. 2015 Apr; 52(2):167-70. Patel J, Klapper E, Shafi H, Kobashigawa JA. PMID: 25748232.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    32. Molecular immunohaematology round table discussions at the AABB Annual Meeting, Denver 2013. Blood Transfus. 2015 Jul; 13(3):514-20. Flegel WA, Castilho L, Delaney M, Klapper EB, Moulds JM, Noizat-Pirenne F, Shehata N, Stack G, Tormey CA, Wagner FF, Waxman DA, Weinstock C, Wendel S, Denomme GA. PMID: 25545874; PMCID: PMC4614304.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    33. A multidisciplinary, multifaceted improvement initiative to eliminate mislabelled laboratory specimens at a large tertiary care hospital. BMJ Qual Saf. 2014 Aug; 23(8):690-7. Seferian EG, Jamal S, Clark K, Cirricione M, Burnes-Bolton L, Amin M, Romanoff N, Klapper E. PMID: 24915540.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. How we incorporate molecular typing of donors and patients into our hospital transfusion service. Transfusion. 2014 May; 54(5):1212-9. Shafi H, Abumuhor I, Klapper E. PMID: 24628032.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    35. Transfusion medicine illustrated. Thromboelastography: a more accurate assessment of global hemostasis. Transfusion. 2013 Nov; 53(11):2605. Shafi H, Tcherniantchouk O, Chaffin DJ, Mason H, Klapper E. PMID: 24719908.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Molecular immunohaematology round table discussions at the AABB Annual Meeting, Boston 2012. Blood Transfus. 2014 Apr; 12(2):280-6. Flegel WA, Johnson ST, Keller MA, Klapper EB, Khuu HM, Moulds JM, Seltsam AW, Stack G, St-Louis M, Tormey CA, Wagner FF, Weinstock C, Yazer MH, Denomme GA. PMID: 24333058; PMCID: PMC4039713.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Platelet-rich plasma for the replenishment of bone. Curr Osteoporos Rep. 2011 Dec; 9(4):258-63. Iqbal J, Pepkowitz SH, Klapper E. PMID: 21993865.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    38. Toward extended phenotype matching: a new operational paradigm for the transfusion service. Transfusion. 2010 Mar; 50(3):536-46. Klapper E, Zhang Y, Figueroa P, Ness P, Stubbs J, Abumuhor I, Bailey J, Epperson L, Tauscher C, Enriquez E, Hashmi G, Seul M. PMID: 19929860.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    39. Acute hemolysis after high-dose intravenous immunoglobulin therapy in highly HLA sensitized patients. Clin J Am Soc Nephrol. 2009 Dec; 4(12):1993-7. Kahwaji J, Barker E, Pepkowitz S, Klapper E, Villicana R, Peng A, Chang R, Jordan SC, Vo AA. PMID: 19833910; PMCID: PMC2798878.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    40. Management of familial hypertriglyceridemia during pregnancy with plasma exchange. J Clin Apher. 2009; 24(1):42-6. Sivakumaran P, Tabak SW, Gregory K, Pepkowitz SH, Klapper EB. PMID: 19160449.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    41. Therapeutic plasma exchange for desensitization prior to transplantation in ABO-incompatible renal allografts. J Clin Apher. 2009; 24(4):155-60. Sivakumaran P, Vo AA, Villicana R, Peng A, Jordan SC, Pepkowitz SH, Klapper EB. PMID: 19658162.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    42. A randomized controlled trial comparing standard- and low-dose strategies for transfusion of platelets (SToP) to patients with thrombocytopenia. Blood. 2009 Feb 12; 113(7):1564-73. Heddle NM, Cook RJ, Tinmouth A, Kouroukis CT, Hervig T, Klapper E, Brandwein JM, Szczepiorkowski ZM, AuBuchon JP, Barty RL, Lee KA, SToP Study Investigators of the BEST Collaborative. PMID: 19109560.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    43. Combination vincristine and plasma exchange as initial therapy in patients with thrombotic thrombocytopenic purpura: one institution's experience and review of the literature. Transfusion. 2005 Jan; 45(1):41-9. Ziman A, Mitri M, Klapper E, Pepkowitz SH, Goldfinger D. PMID: 15647017.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    44. A case-control study of the impact of WBC reduction on the cost of hospital care for patients undergoing coronary artery bypass graft surgery. Transfusion. 2002 Sep; 42(9):1123-6. Volkova N, Klapper E, Pepkowitz SH, Denton T, Gillaspie G, Goldfinger D. PMID: 12430667.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    45. A second case of post-transfusion purpura caused by HPA-5a antibodies: successful treatment with intravenous immunoglobulin. Vox Sang. 2002 Aug; 83(2):165-6. Ziman A, Klapper E, Pepkowitz S, Smith R, Garratty G, Goldfinger D. PMID: 12201847.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    46. Universal WBC reduction and patient advocacy. Transfusion. 2000 Dec; 40(12):1545-6. Goldfinger D, Klapper E, Pepkowitz SH, Millar SI, Heal JM, Blumberg N, Wuest D, Reich L, Mayer K. PMID: 11134580.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    47. Treatment of thrombotic thrombocytopenic purpura: a role for early vincristine administration. J Clin Apher. 1998; 13(1):20-2. Mazzei C, Pepkowitz S, Klapper E, Goldfinger D. PMID: 9590493.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Confirmation of the safety of autologous blood donation by patients awaiting heart or lung transplantation. A controlled study using hemodynamic monitoring. J Thorac Cardiovasc Surg. 1995 Dec; 110(6):1594-9. Klapper E, Pepkowitz SH, Czer L, Inducil C, Scott L, Goldfinger D. PMID: 8523868.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Granular cell tumor of the biliary system. Med Pediatr Oncol. 1994; 23(1):50-6. Mackenzie DJ, Klapper E, Gordon LA, Silberman AW. PMID: 8177145.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. Safety and efficacy of preoperative donation of blood for autologous use by patients with end-stage heart or lung disease who are awaiting organ transplantation. Transfusion. 1993 Apr; 33(4):336-40. Goldfinger D, Capon S, Czer L, Leibfreid J, Trento A, Ross D, Waters P, Klapper E, Pepkowitz S. PMID: 8480355.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. Treatment of babesiosis by red blood cell exchange in an HIV-positive, splenectomized patient. J Clin Apher. 1993; 8(2):78-81. Machtinger L, Telford SR, Inducil C, Klapper E, Pepkowitz SH, Goldfinger D. PMID: 8226709.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    52. Leukocyte-reduced blood components in transfusion medicine. Current indications and prospects for the future. Clin Lab Med. 1992 Dec; 12(4):711-21. Klapper EB, Goldfinger D. PMID: 1286560.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
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