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Forecasted infliximab concentrations during induction predict time to remission and sustained disease control of inflammatory bowel disease. Clin Res Hepatol Gastroenterol. 2024 Jun; 48(6):102374.
Vermeire S, Dubinsky MC, Rabizadeh S, Panetta JC, Spencer EA, Dreesen E, D'Haens G, Dervieux T, Laharie D. PMID: 38750934.
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PubMed Mentions: Fields:
Translation:
Humans
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Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn's disease. World J Gastrointest Surg. 2024 Mar 27; 16(3):740-750.
Gu P, Dube S, Gellada N, Choi SY, Win S, Lee YJ, Yang S, Haritunians T, Melmed GY, Vasiliauskas EA, Bonthala N, Syal G, Yarur AJ, Ziring D, Rabizadeh S, Fleshner P, Kallman C, Devkota S, Targan SR, Li D, McGovern DP. PMID: 38577075; PMCID: PMC10989343.
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Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease. Gastroenterology. 2024 Jul; 167(2):315-332.
Khrom M, Long M, Dube S, Robbins L, Botwin GJ, Yang S, Mengesha E, Li D, Naito T, Bonthala NN, Ha C, Melmed G, Rabizadeh S, Syal G, Vasiliauskas E, Ziring D, Brant SR, Cho J, Duerr RH, Rioux J, Schumm P, Silverberg M, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Xavier RJ, Kugathasan S, Hercules D, Targan SR, Sartor RB, Haritunians T, McGovern DPB. PMID: 38490347; PMCID: PMC11193636.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Comparative Persistence of Non-tumor Necrosis Factor (TNF) vs. TNF Antagonists for Post-operative Prophylaxis in Crohn's Disease (CD). Dig Dis Sci. 2024 Jan; 69(1):235-245.
Gu P, Dube S, Lee Y, Yang S, Li D, Haritunians T, Vasiliauskas E, Bonthala N, Syal G, Yarur A, Ziring D, Targan S, Rabizadeh S, Melmed GY, Fleshner P, McGovern DPB. PMID: 38015321; PMCID: PMC10787872.
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PubMed Mentions: Fields:
Translation:
Humans
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Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis. J Clin Invest. 2023 10 16; 133(20).
Reyes EA, Castillo-Azofeifa D, Rispal J, Wald T, Zwick RK, Palikuqi B, Mujukian A, Rabizadeh S, Gupta AR, Gardner JM, Boffelli D, Gartner ZJ, Klein OD. PMID: 37643009; PMCID: PMC10575728.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization. Clin Gastroenterol Hepatol. 2024 02; 22(2):368-376.e4.
Geem D, Hercules D, Pelia RS, Venkateswaran S, Griffiths A, Noe JD, Dotson JL, Snapper S, Rabizadeh S, Rosh JR, Baldassano RN, Markowitz JF, Walters TD, Ananthakrishnan A, Sharma G, Denson LA, Hyams JS, Kugathasan S. PMID: 37802268.
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Translation:
Humans
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The Combination of Predictive Factors of Pharmacokinetic Origin Associates with Enhanced Disease Control during Treatment of Pediatric Crohn's Disease with Infliximab. Pharmaceutics. 2023 Sep 30; 15(10).
Dubinsky MC, Rabizadeh S, Panetta JC, Spencer EA, Everts-van der Wind A, Dervieux T. PMID: 37896168; PMCID: PMC10610097.
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PubMed Mentions:
1
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Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut. 2023 11; 72(11):2068-2080.
Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M, International IBD Genetics Consortium, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. PMID: 37080587; PMCID: PMC11036449.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Environmental Interaction of Resolved Human Cytomegalovirus Infection With Crohn's Disease Location. Inflamm Bowel Dis. 2023 02 01; 29(2):328-331.
Shih T, Yusung S, Gonsky R, Dutra-Clarke R, Ziring D, Rabizadeh S, Kugathasan S, Denson LA, Li D, Braun J. PMID: 36508344; PMCID: PMC9890217.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Development of a Personalized Intestinal Fibrosis Model Using Human Intestinal Organoids Derived From Induced Pluripotent Stem Cells. Inflamm Bowel Dis. 2022 05 04; 28(5):667-679.
Estrada HQ, Patel S, Rabizadeh S, Casero D, Targan SR, Barrett RJ. PMID: 34918082; PMCID: PMC9074870.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Technical Issues Are a Major Determinant of Patient Satisfaction in Virtual Visits for Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2021 11 15; 27(12):2034-2037.
Ghafari-Saravi A, Rabizadeh S, Dubovsky A, Miller S, Melmed GY, van Deen WK. PMID: 34037212.
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Humans
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Association of Baseline Luminal Narrowing With Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn Disease. Inflamm Bowel Dis. 2021 10 20; 27(11):1707-1718.
Ta AD, Ollberding NJ, Karns R, Haberman Y, Alazraki AL, Hercules D, Baldassano R, Markowitz J, Heyman MB, Kim S, Kirschner B, Shapiro JM, Noe J, Oliva-Hemker M, Otley A, Pfefferkorn M, Kellermayer R, Snapper S, Rabizadeh S, Xavier R, Dubinsky M, Hyams J, Kugathasan S, Jegga AG, Dillman JR, Denson LA. PMID: 33452801; PMCID: PMC8528150.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Decreased Antibody Responses to Ad26.COV2.S Relative to SARS-CoV-2 mRNA Vaccines in Patients With Inflammatory Bowel Disease. Gastroenterology. 2021 12; 161(6):2041-2043.e1.
Pozdnyakova V, Botwin GJ, Sobhani K, Prostko J, Braun J, Mcgovern DPB, Melmed GY, Appel K, Banty A, Feldman E, Ha C, Kumar R, Lee S, Rabizadeh S, Stein T, Syal G, Targan S, Vasiliauskas E, Ziring D, Debbas P, Hampton M, Mengesha E, Stewart JL, Frias EC, Cheng S, Ebinger J, Figueiredo JC, Boland B, Charabaty A, Chiorean M, Cohen E, Flynn A, Valentine J, Fudman D, Horizon A, Hou J, Hwang C, Lazarev M, Lum D, Fausel R, Reddy S, Mattar M, Metwally M, Ostrov A, Parekh N, Raffals L, Sheibani S, Siegel C, Wolf D, Younes Z. PMID: 34391771; PMCID: PMC8359492.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Noninvasive Targeted Crohn Disease Management by Combining Endoscopic Healing Index and Therapeutic Drug Monitoring. Crohns Colitis 360. 2021 Jul; 3(3):otab035.
Hemperly A, Dubinsky MC, Yarur A, Afzali A, Hanauer S, Kugathasan S, Long MD, Rabizadeh S, Sockolow R, Okada L, Jain A, Abreu MT, Vande Casteele N. PMID: 36776644; PMCID: PMC9802228.
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PubMed Mentions:
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Child and Parent Perspectives on the Acceptability of Virtual Reality to Mitigate Medical Trauma in an Infusion Center. Matern Child Health J. 2020 Aug; 24(8):986-997.
Easterlin MC, Berdahl CT, Rabizadeh S, Spiegel B, Agoratus L, Hoover C, Dudovitz R. PMID: 32451966.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Child and Family Perspectives on Adjustment to and Coping With Pediatric Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2020 07; 71(1):e16-e27.
Easterlin MC, Berdahl CT, Rabizadeh S, Spiegel B, Agoratus L, Hoover C, Dudovitz R. PMID: 32142001.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on the Evaluation and Management for Patients With Very Early-onset Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2020 03; 70(3):389-403.
Kelsen JR, Sullivan KE, Rabizadeh S, Singh N, Snapper S, Elkadri A, Grossman AB. PMID: 32079889.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study. Inflamm Bowel Dis. 2019 06 18; 25(7):1208-1217.
Krishnakumar C, Ballengee CR, Liu C, Kim MO, Baker SS, Baldassano RN, Cohen SA, Crandall WV, Denson LA, Dubinsky MC, Evans J, Gokhale R, Griffiths A, Guthery SL, Oliva-Hemker M, Heyman MB, Keljo D, Kellermayer R, Leleiko NS, Mack DR, Markowitz JF, Moulton DE, Noe JD, Otley AR, Patel AS, Pfefferkorn M, Rabizadeh S, Rosh JR, Snapper S, Walters TD, Ziring D, Mondal K, Kappelman MD, Hyams JS, Kugathasan S. PMID: 30601983.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease. Am J Gastroenterol. 2019 05; 114(5):777-785.
Wu J, Lubman DM, Kugathasan S, Denson LA, Hyams JS, Dubinsky MC, Griffiths AM, Baldassano RN, Noe JD, Rabizadeh S, Gulati AS, Rosh JR, Crandall WV, Higgins PDR, Stidham RW. PMID: 31058681; PMCID: PMC6532424.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children. Am J Gastroenterol. 2018 10; 113(10):1524-1529.
Lindoso L, Mondal K, Venkateswaran S, Somineni HK, Ballengee C, Walters TD, Griffiths A, Noe JD, Crandall W, Snapper S, Rabizadeh S, Rosh JR, LeLeiko N, Guthery S, Mack D, Kellermayer R, Gulati AS, Pfefferkorn MD, Moulton DE, Keljo D, Cohen S, Oliva-Hemker M, Heyman MB, Otley A, Baker SS, Evans JS, Kirschner BS, Patel AS, Ziring D, Stephens MC, Baldassano R, Dubinsky MC, Markowitz J, Denson LA, Hyams J, Kugathasan S, Ananthakrishnan AN. PMID: 30267029.
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PubMed Mentions:
15 Fields:
Translation:
HumansPHPublic Health
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Evolution of Pediatric Inflammatory Bowel Disease Unclassified (IBD-U): Incorporated With Serological and Gene Expression Profiles. Inflamm Bowel Dis. 2018 09 15; 24(10):2285-2290.
Chandradevan R, Hofmekler T, Mondal K, Harun N, Venkateswaran S, Somineni HK, Ballengee CR, Kim MO, Griffiths A, Noe JD, Crandall WV, Snapper S, Rabizadeh S, Rosh JR, Walters TD, Bertha M, Dubinsky MC, Denson LA, Sauer CG, Markowitz JF, LeLeiko NS, Hyams JS, Kugathasan S. PMID: 29860529.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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New melanocortin-like peptide of E. coli can suppress inflammation via the mammalian melanocortin-1 receptor (MC1R): possible endocrine-like function for microbes of the gut. NPJ Biofilms Microbiomes. 2017; 3:31.
Qiang X, Liotta AS, Shiloach J, Gutierrez JC, Wang H, Ochani M, Ochani K, Yang H, Rabin A, LeRoith D, Lesniak MA, Böhm M, Maaser C, Kannengiesser K, Donowitz M, Rabizadeh S, Czura CJ, Tracey KJ, Westlake M, Zarfeshani A, Mehdi SF, Danoff A, Ge X, Sanyal S, Schwartz GJ, Roth J. PMID: 29152323; PMCID: PMC5684143.
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PubMed Mentions:
9 Fields:
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Colonic Phenotypes Are Associated with Poorer Response to Anti-TNF Therapies in Patients with IBD. Inflamm Bowel Dis. 2017 08; 23(8):1382-1393.
Yoon SM, Haritunians T, Chhina S, Liu Z, Yang S, Landers C, Li D, Ye BD, Shih D, Vasiliauskas EA, Ippoliti A, Rabizadeh S, Targan SR, Melmed GY, McGovern DPB. PMID: 28590340; PMCID: PMC6510223.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study. Lancet. 2017 04 29; 389(10080):1710-1718.
Kugathasan S, Denson LA, Walters TD, Kim MO, Marigorta UM, Schirmer M, Mondal K, Liu C, Griffiths A, Noe JD, Crandall WV, Snapper S, Rabizadeh S, Rosh JR, Shapiro JM, Guthery S, Mack DR, Kellermayer R, Kappelman MD, Steiner S, Moulton DE, Keljo D, Cohen S, Oliva-Hemker M, Heyman MB, Otley AR, Baker SS, Evans JS, Kirschner BS, Patel AS, Ziring D, Trapnell BC, Sylvester FA, Stephens MC, Baldassano RN, Markowitz JF, Cho J, Xavier RJ, Huttenhower C, Aronow BJ, Gibson G, Hyams JS, Dubinsky MC. PMID: 28259484; PMCID: PMC5719489.
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PubMed Mentions:
231 Fields:
Translation:
HumansCTClinical Trials
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Pharmacokinetic Dashboard-Recommended Dosing Is Different than Standard of Care Dosing in Infliximab-Treated Pediatric IBD Patients. AAPS J. 2017 01; 19(1):215-222.
Dubinsky MC, Phan BL, Singh N, Rabizadeh S, Mould DR. PMID: 27739008.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Multi-Center Experience of Vedolizumab Effectiveness in Pediatric Inflammatory Bowel Disease. Inflamm Bowel Dis. 2016 09; 22(9):2121-6.
Singh N, Rabizadeh S, Jossen J, Pittman N, Check M, Hashemi G, Phan BL, Hyams JS, Dubinsky MC. PMID: 27542130.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Outcomes with Anti-Tumour Necrosis Factor-Alpha Therapy and Serology in Patients with Denovo Crohn's Disease After Ileal Pouch Anal Anastomosis. J Crohns Colitis. 2017 Jan; 11(1):77-83.
Robbins L, Zaghiyan K, Melmed G, Vasiliauskas E, Ahmed S, McGovern D, Rabizadeh S, Singh N, Landers C, Ippoliti A, Shih D, Targan S, Fleshner P. PMID: 27466172.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Clinical Factors Associated with the Development of Crohn's Disease in Inflammatory Bowel Disease-unclassified Patients Undergoing Ileal Pouch-anal Anastomosis. Inflamm Bowel Dis. 2016 06; 22(6):1397-402.
Koh SZ, Zaghiyan KN, Li Q, Rabizadeh S, Melmed GY, Targan SR, Fleshner PR. PMID: 26978722.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Real World Experience With Natalizumab at a Tertiary Care Pediatric IBD Center. J Pediatr Gastroenterol Nutr. 2016 06; 62(6):863-6.
Singh N, Deshpande R, Rabizadeh S, Dubinsky M. PMID: 27213249.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Early infliximab trough levels are associated with persistent remission in pediatric patients with inflammatory bowel disease. Inflamm Bowel Dis. 2014 Oct; 20(10):1708-13.
Singh N, Rosenthal CJ, Melmed GY, Mirocha J, Farrior S, Callejas S, Tripuraneni B, Rabizadeh S, Dubinsky MC. PMID: 25153505.
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PubMed Mentions:
53 Fields:
Translation:
Humans
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Stat3 activation in murine colitis induced by enterotoxigenic Bacteroides fragilis. Inflamm Bowel Dis. 2014 May; 20(5):821-34.
Wick EC, Rabizadeh S, Albesiano E, Wu X, Wu S, Chan J, Rhee KJ, Ortega G, Huso DL, Pardoll D, Housseau F, Sears CL. PMID: 24704822; PMCID: PMC4121853.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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A 10-year, single tertiary care center experience on the durability of infliximab in pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2014 Apr; 20(4):606-13.
Vahabnezhad E, Rabizadeh S, Dubinsky MC. PMID: 24552827; PMCID: PMC5330671.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Clostridium difficile carriage and serum antitoxin responses in children with inflammatory bowel disease. Inflamm Bowel Dis. 2013 Dec; 19(13):2744-52.
Hourigan SK, Chirumamilla SR, Ross T, Golub JE, Rabizadeh S, Saeed SA, Elson CO, Kelly CP, Carroll KC, Oliva-Hemker M, Sears C. PMID: 24145927.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Video capsule endoscopy impacts decision making in pediatric IBD: a single tertiary care center experience. Inflamm Bowel Dis. 2013 Sep; 19(10):2139-45.
Min SB, Le-Carlson M, Singh N, Nylund CM, Gebbia J, Haas K, Lo S, Mann N, Melmed GY, Rabizadeh S, Dubinsky MC. PMID: 23867872.
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PubMed Mentions:
14 Fields:
Translation:
HumansCTClinical Trials
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Update in pediatric inflammatory bowel disease. Rheum Dis Clin North Am. 2013 Nov; 39(4):789-99.
Rabizadeh S, Dubinsky M. PMID: 24182855; PMCID: PMC3817417.
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PubMed Mentions:
14 Fields:
Translation:
HumansPHPublic Health
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Distinct phenotypes of children with perianal perforating Crohn's disease. J Pediatr Surg. 2013 Jun; 48(6):1301-5.
Short SS, Dubinsky MC, Rabizadeh S, Farrior S, Berel D, Frykman PK. PMID: 23845622; PMCID: PMC4372139.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Restructuring the Morbidity and Mortality Conference in a Department of Pediatrics to serve as a vehicle for system changes. Clin Pediatr (Phila). 2012 Nov; 51(11):1079-86.
Rabizadeh S, Gower WA, Payton K, Miller K, Vera K, Serwint JR. PMID: 23034949.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis. Proc Natl Acad Sci U S A. 2011 Sep 13; 108(37):15354-9.
Goodwin AC, Destefano Shields CE, Wu S, Huso DL, Wu X, Murray-Stewart TR, Hacker-Prietz A, Rabizadeh S, Woster PM, Sears CL, Casero RA. PMID: 21876161; PMCID: PMC3174648.
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PubMed Mentions:
267 Fields:
Translation:
HumansAnimalsCells
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Primary EBV infection resulting in lymphoproliferative disease in a teenager with Crohn disease. J Pediatr Gastroenterol Nutr. 2011 Jan; 52(1):103-5.
Gidrewicz D, Lehman D, Rabizadeh S, Majlessipour F, Dubinsky M. PMID: 20890216.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis. PLoS One. 2010 Oct 15; 5(10):e15044.
Soliman A, Michelsen KS, Karahashi H, Lu J, Meng FJ, Qu X, Crother TR, Rabizadeh S, Chen S, Caplan MS, Arditi M, Jilling T. PMID: 20976181; PMCID: PMC2955554.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer. PLoS One. 2010 Sep 27; 5(9):e13027.
Lowe EL, Crother TR, Rabizadeh S, Hu B, Wang H, Chen S, Shimada K, Wong MH, Michelsen KS, Arditi M. PMID: 20885960; PMCID: PMC2946405.
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PubMed Mentions:
74 Fields:
Translation:
HumansAnimalsCells
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A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med. 2009 Sep; 15(9):1016-22.
Wu S, Rhee KJ, Albesiano E, Rabizadeh S, Wu X, Yen HR, Huso DL, Brancati FL, Wick E, McAllister F, Housseau F, Pardoll DM, Sears CL. PMID: 19701202; PMCID: PMC3034219.
View in:
PubMed Mentions:
791 Fields:
Translation:
HumansAnimalsCells
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Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice. Infect Immun. 2009 Apr; 77(4):1708-18.
Rhee KJ, Wu S, Wu X, Huso DL, Karim B, Franco AA, Rabizadeh S, Golub JE, Mathews LE, Shin J, Sartor RB, Golenbock D, Hamad AR, Gan CM, Housseau F, Sears CL. PMID: 19188353; PMCID: PMC2663167.
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PubMed Mentions:
149 Fields:
Translation:
HumansAnimalsCells
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New horizons for the infectious diseases specialist: how gut microflora promote health and disease. Curr Infect Dis Rep. 2008 May; 10(2):92-8.
Rabizadeh S, Sears C. PMID: 18462581; PMCID: PMC3074359.
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PubMed Mentions:
14
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Enterotoxigenic bacteroides fragilis: a potential instigator of colitis. Inflamm Bowel Dis. 2007 Dec; 13(12):1475-83.
Rabizadeh S, Rhee KJ, Wu S, Huso D, Gan CM, Golub JE, Wu X, Zhang M, Sears CL. PMID: 17886290; PMCID: PMC3056612.
View in:
PubMed Mentions:
65 Fields:
Translation:
AnimalsCells