David Ziring

Title(s)HS Clinical Professor, Pediatrics
SchoolMedicine
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn's disease. World J Gastrointest Surg. 2024 Mar 27; 16(3):740-750. Gu P, Dube S, Gellada N, Choi SY, Win S, Lee YJ, Yang S, Haritunians T, Melmed GY, Vasiliauskas EA, Bonthala N, Syal G, Yarur AJ, Ziring D, Rabizadeh S, Fleshner P, Kallman C, Devkota S, Targan SR, Li D, McGovern DP. PMID: 38577075; PMCID: PMC10989343.
      View in: PubMed   Mentions:
    2. Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease. Gastroenterology. 2024 Jul; 167(2):315-332. Khrom M, Long M, Dube S, Robbins L, Botwin GJ, Yang S, Mengesha E, Li D, Naito T, Bonthala NN, Ha C, Melmed G, Rabizadeh S, Syal G, Vasiliauskas E, Ziring D, Brant SR, Cho J, Duerr RH, Rioux J, Schumm P, Silverberg M, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Xavier RJ, Kugathasan S, Hercules D, Targan SR, Sartor RB, Haritunians T, McGovern DPB. PMID: 38490347; PMCID: PMC11193636.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Comparative Persistence of Non-tumor Necrosis Factor (TNF) vs. TNF Antagonists for Post-operative Prophylaxis in Crohn's Disease (CD). Dig Dis Sci. 2024 Jan; 69(1):235-245. Gu P, Dube S, Lee Y, Yang S, Li D, Haritunians T, Vasiliauskas E, Bonthala N, Syal G, Yarur A, Ziring D, Targan S, Rabizadeh S, Melmed GY, Fleshner P, McGovern DPB. PMID: 38015321; PMCID: PMC10787872.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Effectiveness of Oral Tofacitinib in Chronic Pouchitis: A Prospective, Open-Label Pilot Study. Inflamm Bowel Dis. 2023 Oct 28. Syal G, Mishkin DS, Banty A, Lee S, Fontelera N, Hampton M, Ziring D, Fleshner PR, Melmed GY. PMID: 37898112.
      View in: PubMed   Mentions:    Fields:    
    5. Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut. 2023 11; 72(11):2068-2080. Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M, International IBD Genetics Consortium, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. PMID: 37080587; PMCID: PMC11036449.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Environmental Interaction of Resolved Human Cytomegalovirus Infection With Crohn's Disease Location. Inflamm Bowel Dis. 2023 02 01; 29(2):328-331. Shih T, Yusung S, Gonsky R, Dutra-Clarke R, Ziring D, Rabizadeh S, Kugathasan S, Denson LA, Li D, Braun J. PMID: 36508344; PMCID: PMC9890217.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Decreased Antibody Responses to Ad26.COV2.S Relative to SARS-CoV-2 mRNA Vaccines in Patients With Inflammatory Bowel Disease. Gastroenterology. 2021 12; 161(6):2041-2043.e1. Pozdnyakova V, Botwin GJ, Sobhani K, Prostko J, Braun J, Mcgovern DPB, Melmed GY, Appel K, Banty A, Feldman E, Ha C, Kumar R, Lee S, Rabizadeh S, Stein T, Syal G, Targan S, Vasiliauskas E, Ziring D, Debbas P, Hampton M, Mengesha E, Stewart JL, Frias EC, Cheng S, Ebinger J, Figueiredo JC, Boland B, Charabaty A, Chiorean M, Cohen E, Flynn A, Valentine J, Fudman D, Horizon A, Hou J, Hwang C, Lazarev M, Lum D, Fausel R, Reddy S, Mattar M, Metwally M, Ostrov A, Parekh N, Raffals L, Sheibani S, Siegel C, Wolf D, Younes Z. PMID: 34391771; PMCID: PMC8359492.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    8. Ewing's Sarcoma in a Patient with Crohn's Disease Treated with Ustekinumab: A Case Report. J Adolesc Young Adult Oncol. 2021 10; 10(5):614-617. Rao RR, Majlessipour F, Ziring DA, Baca NM. PMID: 32960134.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease. J Crohns Colitis. 2020 Aug 08. Haberman Y, Minar P, Karns R, Dexheimer PJ, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Ta A, Walters TD, Baldassano RN, Noe JD, Rosh J, Markowitz J, Dotson JL, Mack DR, Kellermayer R, Griffiths AM, Heyman MB, Baker SS, Moulton D, Patel AS, Gulati AS, Steiner SJ, LeLeiko N, Otley A, Oliva-Hemker M, Ziring D, Gokhale R, Kim S, Guthery SL, Cohen SA, Snapper S, Aronow BJ, Stephens M, Gibson G, Dillman JR, Dubinsky M, Hyams JS, Kugathasan S, Jegga AG, Denson LA. PMID: 32770196; PMCID: PMC7904088.
      View in: PubMed   Mentions: 14     Fields:    
    10. Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study. Inflamm Bowel Dis. 2019 06 18; 25(7):1208-1217. Krishnakumar C, Ballengee CR, Liu C, Kim MO, Baker SS, Baldassano RN, Cohen SA, Crandall WV, Denson LA, Dubinsky MC, Evans J, Gokhale R, Griffiths A, Guthery SL, Oliva-Hemker M, Heyman MB, Keljo D, Kellermayer R, Leleiko NS, Mack DR, Markowitz JF, Moulton DE, Noe JD, Otley AR, Patel AS, Pfefferkorn M, Rabizadeh S, Rosh JR, Snapper S, Walters TD, Ziring D, Mondal K, Kappelman MD, Hyams JS, Kugathasan S. PMID: 30601983.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    11. Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study. Lancet. 2019 04 27; 393(10182):1708-1720. Hyams JS, Davis Thomas S, Gotman N, Haberman Y, Karns R, Schirmer M, Mo A, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh J, Baldassano RN, Patel A, Pfefferkorn M, Otley A, Heyman M, Noe J, Oliva-Hemker M, Rufo PA, Strople J, Ziring D, Guthery SL, Sudel B, Benkov K, Wali P, Moulton D, Evans J, Kappelman MD, Marquis MA, Sylvester FA, Collins MH, Venkateswaran S, Dubinsky M, Tangpricha V, Spada KL, Saul B, Wang J, Serrano J, Hommel K, Marigorta UM, Gibson G, Xavier RJ, Kugathasan S, Walters T, Denson LA. PMID: 30935734; PMCID: PMC6501846.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCTClinical Trials
    12. Pediatric Inflammatory Bowel Disease Clinical Innovations Meeting of the Crohn's & Colitis Foundation: Charting the Future of Pediatric IBD. Inflamm Bowel Dis. 2019 01 01; 25(1):27-32. Picoraro JA, Lee D, Heller CA, Weaver A, Hyams JS, Conklin LS, Otley A, Ziring D, Kugathasan S, Rosh JR, Mulberg A, Denson LA, Kappelman MD, Grossman AB, Bousvaros A, Park KT. PMID: 29931102; PMCID: PMC8133504.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    13. Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis. Mucosal Immunol. 2019 03; 12(2):491-502. Haberman Y, Schirmer M, Dexheimer PJ, Karns R, Braun T, Kim MO, Walters TD, Baldassano RN, Noe JD, Rosh J, Markowitz J, Crandall WV, Mack DR, Griffiths AM, Heyman MB, Baker SS, Kellermayer R, Moulton D, Patel AS, Gulati AS, Steiner SJ, LeLeiko N, Otley A, Oliva-Hemker M, Ziring D, Kirschner BS, Keljo DJ, Guthery SL, Cohen SA, Snapper S, Evans J, Dubinsky M, Aronow B, Hyams JS, Kugathasan S, Huttenhower C, Xavier RJ, Denson LA. PMID: 30542108; PMCID: PMC6375755.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    14. The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children. Am J Gastroenterol. 2018 10; 113(10):1524-1529. Lindoso L, Mondal K, Venkateswaran S, Somineni HK, Ballengee C, Walters TD, Griffiths A, Noe JD, Crandall W, Snapper S, Rabizadeh S, Rosh JR, LeLeiko N, Guthery S, Mack D, Kellermayer R, Gulati AS, Pfefferkorn MD, Moulton DE, Keljo D, Cohen S, Oliva-Hemker M, Heyman MB, Otley A, Baker SS, Evans JS, Kirschner BS, Patel AS, Ziring D, Stephens MC, Baldassano R, Dubinsky MC, Markowitz J, Denson LA, Hyams J, Kugathasan S, Ananthakrishnan AN. PMID: 30267029.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    15. Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease. Inflamm Bowel Dis. 2018 01 18; 24(2):346-360. Haberman Y, BenShoshan M, Di Segni A, Dexheimer PJ, Braun T, Weiss B, Walters TD, Baldassano RN, Noe JD, Markowitz J, Rosh J, Heyman MB, Griffiths AM, Crandall WV, Mack DR, Baker SS, Kellermayer R, Patel A, Otley A, Steiner SJ, Gulati AS, Guthery SL, LeLeiko N, Moulton D, Kirschner BS, Snapper S, Avivi C, Barshack I, Oliva-Hemker M, Cohen SA, Keljo DJ, Ziring D, Anikster Y, Aronow B, Hyams JS, Kugathasan S, Denson LA. PMID: 29361088; PMCID: PMC6231367.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    16. Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study. Lancet Gastroenterol Hepatol. 2017 12; 2(12):855-868. Hyams JS, Davis S, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh J, Baldassano RN, Patel A, Pfefferkorn M, Otley A, Heyman M, Noe J, Oliva-Hemker M, Rufo P, Strople J, Ziring D, Guthery SL, Sudel B, Benkov K, Wali P, Moulton D, Evans J, Kappelman MD, Marquis A, Sylvester FA, Collins MH, Venkateswaran S, Dubinsky M, Tangpricha V, Spada KL, Britt A, Saul B, Gotman N, Wang J, Serrano J, Kugathasan S, Walters T, Denson LA. PMID: 28939374; PMCID: PMC5695708.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    17. Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study. Lancet. 2017 04 29; 389(10080):1710-1718. Kugathasan S, Denson LA, Walters TD, Kim MO, Marigorta UM, Schirmer M, Mondal K, Liu C, Griffiths A, Noe JD, Crandall WV, Snapper S, Rabizadeh S, Rosh JR, Shapiro JM, Guthery S, Mack DR, Kellermayer R, Kappelman MD, Steiner S, Moulton DE, Keljo D, Cohen S, Oliva-Hemker M, Heyman MB, Otley AR, Baker SS, Evans JS, Kirschner BS, Patel AS, Ziring D, Trapnell BC, Sylvester FA, Stephens MC, Baldassano RN, Markowitz JF, Cho J, Xavier RJ, Huttenhower C, Aronow BJ, Gibson G, Hyams JS, Dubinsky MC. PMID: 28259484; PMCID: PMC5719489.
      View in: PubMed   Mentions: 225     Fields:    Translation:HumansCTClinical Trials
    18. Out-of-pocket Cost Burden in Pediatric Inflammatory Bowel Disease: A Cross-sectional Cohort Analysis. Inflamm Bowel Dis. 2015 Jun; 21(6):1368-77. Sin AT, Damman JL, Ziring DA, Gleghorn EE, Garcia-Careaga MG, Gugig RR, Hunter AK, Burgis JC, Bass DM, Park KT. PMID: 25839776; PMCID: PMC4437842.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    19. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflamm Bowel Dis. 2015 May; 21(5):996-1005. Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. PMID: 25738378; PMCID: PMC4402238.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimals
    20. Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease. Gastroenterology. 2014 Feb; 146(2):383-91. Walters TD, Kim MO, Denson LA, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh J, Pfefferkorn M, Otley A, Heyman MB, LeLeiko N, Baker S, Guthery SL, Evans J, Ziring D, Kellermayer R, Stephens M, Mack D, Oliva-Hemker M, Patel AS, Kirschner B, Moulton D, Cohen S, Kim S, Liu C, Essers J, Kugathasan S, Hyams JS, PRO-KIIDS Research Group. PMID: 24162032.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    21. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013 May-Jun; 47(5):437-9. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. PMID: 23426446.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    22. Postoperative complications and health care use in children undergoing surgery for ulcerative colitis. J Pediatr Surg. 2012 Nov; 47(11):2063-70. Kelley-Quon LI, Tseng CH, Jen HC, Ziring DA, Shew SB. PMID: 23163999.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    23. Predictors of proctocolectomy in children with ulcerative colitis. J Pediatr Gastroenterol Nutr. 2012 Nov; 55(5):534-40. Kelley-Quon LI, Jen HC, Ziring DA, Gupta N, Kirschner BS, Ferry GD, Cohen SA, Winter HS, Heyman MB, Gold BD, Shew SB. PMID: 22684351; PMCID: PMC4378533.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    24. Proteomic analysis reveals innate immune activity in intestinal transplant dysfunction. Transplantation. 2011 Jul 15; 92(1):112-9. Kumar AR, Li X, Leblanc JF, Farmer DG, Elashoff D, Braun J, Ziring D. PMID: 21527871; PMCID: PMC3461584.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    25. Pediatric inflammatory bowel disease research: on the cutting-edge. Pediatr Res. 2008 Aug; 64(2):119-20. Ziring DA, Braun J. PMID: 18645458; PMCID: PMC3762704.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Molecular imaging of murine intestinal inflammation with 2-deoxy-2-[18F]fluoro-D-glucose and positron emission tomography. Gastroenterology. 2008 Sep; 135(3):744-55. Brewer S, McPherson M, Fujiwara D, Turovskaya O, Ziring D, Chen L, Takedatsu H, Targan SR, Wei B, Braun J. PMID: 18639553; PMCID: PMC3752978.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    27. TNFalpha blockade in human diseases: an overview of efficacy and safety. Clin Immunol. 2008 Jan; 126(1):13-30. Lin J, Ziring D, Desai S, Kim S, Wong M, Korin Y, Braun J, Reed E, Gjertson D, Singh RR. PMID: 17916445; PMCID: PMC2291511.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    28. TNFalpha blockade in human diseases: mechanisms and future directions. Clin Immunol. 2008 Feb; 126(2):121-36. Wong M, Ziring D, Korin Y, Desai S, Kim S, Lin J, Gjertson D, Braun J, Reed E, Singh RR. PMID: 17916444; PMCID: PMC2291518.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimals
    29. Oral tacrolimus for steroid-dependent and steroid-resistant ulcerative colitis in children. J Pediatr Gastroenterol Nutr. 2007 Sep; 45(3):306-11. Ziring DA, Wu SS, Mow WS, Martín MG, Mehra M, Ament ME. PMID: 17873742.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    30. Formation of B and T cell subsets require the cannabinoid receptor CB2. Immunogenetics. 2006 Sep; 58(9):714-25. Ziring D, Wei B, Velazquez P, Schrage M, Buckley NE, Braun J. PMID: 16924491.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    31. Infectious enteritis after intestinal transplantation: incidence, timing, and outcome. Transplantation. 2005 Mar 27; 79(6):702-9. Ziring D, Tran R, Edelstein S, McDiarmid SV, Gajjar N, Cortina G, Vargas J, Renz JF, Cherry JD, Krogstad P, Miller M, Busuttil RW, Farmer DG. PMID: 15785377.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    32. Role of macrophages and stellate cells in the pathogenesis of veno-occlusive disease: an electron microscopic case study. Exp Mol Pathol. 2003 Dec; 75(3):201-9. Tang W, Ziring D, Gershman G, French S. PMID: 14611811.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
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