Ram Raj Singh

Title(s)Professor, Medicine
SchoolMedicine
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    Other Positions
    Title(s)Professor, Pathology and Laboratory Medicine


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    Role of Innate B1 B Cells in the Development of Diffuse Lung Hemorrhage
    NIH R21ES026536Aug 1, 2016 - Jul 31, 2019
    Role: Principal Investigator
    Decidual T Cells in Immune-mediated Pregnancy Loss
    NIH R21HD082812Jul 15, 2015 - Jun 30, 2018
    Role: Principal Investigator
    Pathogenesis of Lupus Dermatitis
    NIH R01AI080778Jul 6, 2009 - Jun 30, 2015
    Role: Principal Investigator
    Gender Bias in Lupus: Contribution of Sex Chromosomes
    NIH R01AR056465Sep 1, 2008 - Aug 31, 2014
    Role: Principal Investigator
    Academic Training in Rheumatology
    NIH T32AR053463Jun 1, 2007 - May 31, 2013
    Role: Principal Investigator
    Augementing Peptide-specific Tolerance in ImmuneNephrit*
    NIH R21DK069282Aug 1, 2004 - Jul 31, 2006
    Role: Principal Investigator
    Kidney Damage in Murine Lupus
    NIH R01AR050797Sep 30, 2003 - May 31, 2008
    Role: Principal Investigator
    Peptide Gene Vaccination in Lupus
    NIH R01AR047322Aug 15, 2001 - May 31, 2007
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Worsening premature death burden gap from systemic sclerosis in men and black persons: A US nationwide population-based study. J Scleroderma Relat Disord. 2023 Feb; 8(1):20-26. Singh RR, Singh DR, Yen EY. PMID: 36743809; PMCID: PMC9896199.
      View in: PubMed   Mentions:
    2. Diverse Roles of NETosis in the Pathogenesis of Lupus. Front Immunol. 2022; 13:895216. Wang M, Ishikawa T, Lai Y, Nallapothula D, Singh RR. PMID: 35686129; PMCID: PMC9170953.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    3. Trends in Systemic Sclerosis Mortality Over Forty-Eight Years, 1968-2015: A US Population-Based Study. Arthritis Care Res (Hoboken). 2021 10; 73(10):1502-1510. Yen EY, Singh DR, Singh RR. PMID: 32770721; PMCID: PMC7868470.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    4. Anti-vinculin antibodies in scleroderma (SSc): a potential link between autoimmunity and gastrointestinal system involvement in two SSc cohorts. Clin Rheumatol. 2021 Jun; 40(6):2277-2284. Suliman Y, Kafaja S, Oh SJ, Alemam M, Bagnato G, Abignano G, Singh RR, Barlow G, Liu X, Valera I, Morales W, Rezaie A, Pimentel M, Del Galdo F, Furst DE. PMID: 33231773.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    5. Heparin and aspirin combination therapy restores T-cell phenotype in pregnant patients with antiphospholipid syndrome-related recurrent pregnancy loss. Clin Immunol. 2019 11; 208:108259. Wang M, Zhang P, Yu S, Zhou G, Lv J, Nallapothula D, Guo C, Wang Q, Singh RR. PMID: 31513884.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    6. Generalized Cytokine Increase in the Setting of a Multisystem Clinical Disorder and Carcinoid Syndrome Associated with a Novel NLRP12 Variant. Dig Dis Sci. 2019 08; 64(8):2140-2146. Jacob N, Dasharathy SS, Bui V, Benhammou JN, Grody WW, Singh RR, Pisegna JR. PMID: 30788684; PMCID: PMC6707534.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Self-glycerophospholipids activate murine phospholipid-reactive T cells and inhibit iNKT cell activation by competing with ligands for CD1d loading. Eur J Immunol. 2019 02; 49(2):242-254. Halder RC, Tran C, Prasad P, Wang J, Nallapothula D, Ishikawa T, Wang M, Zajonc DM, Singh RR. PMID: 30508304; PMCID: PMC6405219.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    8. Effects of Invariant NKT Cells on Parasite Infections and Hygiene Hypothesis. J Immunol Res. 2016; 2016:2395645. Yang JQ, Zhou Y, Singh RR. PMID: 27563682; PMCID: PMC4987483.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    9. Langerhans Cells Maintain Local Tissue Tolerance in a Model of Systemic Autoimmune Disease. J Immunol. 2015 Jul 15; 195(2):464-76. King JK, Philips RL, Eriksson AU, Kim PJ, Halder RC, Lee DJ, Singh RR. PMID: 26071559; PMCID: PMC4562401.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    10. A one-year, phase I/IIa, open-label pilot trial of imatinib mesylate in the treatment of systemic sclerosis-associated active interstitial lung disease. Arthritis Rheum. 2011 Nov; 63(11):3540-6. Khanna D, Saggar R, Mayes MD, Abtin F, Clements PJ, Maranian P, Assassi S, Saggar R, Singh RR, Furst DE. PMID: 21769849; PMCID: PMC3205223.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCTClinical Trials
    11. Homeostatic regulation of marginal zone B cells by invariant natural killer T cells. PLoS One. 2011; 6(10):e26536. Wen X, Yang JQ, Kim PJ, Singh RR. PMID: 22046304; PMCID: PMC3202546.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    12. Brief treatment with iNKT cell ligand a-galactosylceramide confers a long-term protection against lupus. J Clin Immunol. 2012 Feb; 32(1):106-13. Yang JQ, Kim PJ, Singh RR. PMID: 22002593; PMCID: PMC3432318.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    13. Treatment with imatinib results in reduced IL-4-producing T cells, but increased CD4(+) T cells in the broncho-alveolar lavage of patients with systemic sclerosis. Clin Immunol. 2011 Dec; 141(3):293-303. Divekar AA, Khanna D, Abtin F, Maranian P, Saggar R, Saggar R, Furst DE, Singh RR. PMID: 22015344; PMCID: PMC3221795.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    14. Invariant NKT cells inhibit autoreactive B cells in a contact- and CD1d-dependent manner. J Immunol. 2011 Feb 01; 186(3):1512-20. Yang JQ, Wen X, Kim PJ, Singh RR. PMID: 21209282; PMCID: PMC3039137.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    15. Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieu. J Immunol. 2011 Jan 15; 186(2):924-30. Divekar AA, Dubey S, Gangalum PR, Singh RR. PMID: 21149603; PMCID: PMC3038632.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    16. Cutting edge: migration of langerhans dendritic cells is impaired in autoimmune dermatitis. J Immunol. 2008 Dec 01; 181(11):7468-72. Eriksson AU, Singh RR. PMID: 19017935; PMCID: PMC2766617.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    17. Dual roles of immunoregulatory cytokine TGF-beta in the pathogenesis of autoimmunity-mediated organ damage. J Immunol. 2008 Feb 01; 180(3):1903-12. Saxena V, Lienesch DW, Zhou M, Bommireddy R, Azhar M, Doetschman T, Singh RR. PMID: 18209088; PMCID: PMC2291535.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    18. TNFalpha blockade in human diseases: an overview of efficacy and safety. Clin Immunol. 2008 Jan; 126(1):13-30. Lin J, Ziring D, Desai S, Kim S, Wong M, Korin Y, Braun J, Reed E, Gjertson D, Singh RR. PMID: 17916445; PMCID: PMC2291511.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    19. TNFalpha blockade in human diseases: mechanisms and future directions. Clin Immunol. 2008 Feb; 126(2):121-36. Wong M, Ziring D, Korin Y, Desai S, Kim S, Lin J, Gjertson D, Braun J, Reed E, Singh RR. PMID: 17916444; PMCID: PMC2291518.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimals
    20. SLE: translating lessons from model systems to human disease. Trends Immunol. 2005 Nov; 26(11):572-9. Singh RR. PMID: 16153890; PMCID: PMC2291517.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    21. Cellular and molecular mechanisms of regulation of autoantibody production in lupus. Ann N Y Acad Sci. 2005 Jun; 1051:433-41. Hahn BH, Ebling F, Singh RR, Singh RP, Karpouzas G, La Cava A. PMID: 16126985; PMCID: PMC2291525.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    22. CD1d deficiency exacerbates inflammatory dermatitis in MRL-lpr/lpr mice. Eur J Immunol. 2004 Jun; 34(6):1723-32. Yang JQ, Chun T, Liu H, Hong S, Bui H, Van Kaer L, Wang CR, Singh RR. PMID: 15162443; PMCID: PMC2291526.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
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