As a researcher, one of my key interests has centered on host-pathogen interactions. This has led me to investigate how Borrelia burgdorferi, the causative agent of Lyme Disease, remakes itself when it infects a mammalian host, and how Chlamydia pneumoniae infections can drive asthmatic responses, and also exacerbate atherosclerotic plaque development. More recently, I have become interested in the possibility that infectious agents may play a role in the development and progression of Alzheimer’s Disease. While there is evidence that infections may play a role in AD, few direct studies have been attempted, highlighting the need for new investigations.