Mariko Lisa Ishimori

Title(s)HS Clinical Professor, Medicine
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    Collapse Biography 
    Collapse Education and Training
    Stanford University, Stanford, CAB.S.05/1994Biology
    New York Medical College, Valhalla, NYMD06/2000Medicine
    Cedars-Sinai Medical Center, Los Angeles, CAResidency2003Internal Medicine
    Cedars-Sinai Medical Center, Los Angeles, CAFellowship2006Rheumatology
    University of California, Los Angeles, CACertificate2009NIH K30 Program/Translational Research
    Collapse Awards and Honors
    Japanese Medical Society of America1997  - 1998Dr. Terusada Horiguchi Scholarship Award Recipient
    Cedars-Sinai Medical Center2003  - 2004Outstanding Clinical Fellow Award, Department of Medicine
    NYU-HJD Seminar in Advaned Rheumatology2005Fellows Travel Scholarship Award
    American College of Rheumatology2006Distinguished Fellow Award

    Collapse Overview 
    Collapse Overview
    Over the past 10 years, Dr. Mariko Ishimori has been involved with the UCLA CTSI, initially serving on the Curriculum Subcommittee of the Training Program in Translational Science (TPTS) in the first grant cycle and in more recent years, as the site co-Leader, working with Brennan Spiegel, site Leader, for Cedars-Sinai in the UCLA CTSI. Dr. Ishimori is also involved with the Program Areas of Workforce Development, Team Science, and PCI.

    Dr. Ishimori's scientific endeavors have been mainly focused in the study of systemic lupus erythematosus (SLE) and hand osteoarthritis (HOA). I have experience in designing, recruiting and conducting clinical translational studies in SLE and HOA. In SLE, Dr. Ishimori has successfully collaborated with investigators at multiple academic medical centers nationally, studying patients with systemic lupus erythematosus (SLE) and their first-degree relatives to study risk factors associated with antibody development, progression to disease and disease manifestations.

    In HOA, Dr. Ishimori is a member of 2 collaborative efforts. The first is the OMERACT working group to define a core set of outcome measures in HOA, which involves HOA experts from around the world. In addition, she is also a member of the European League Against Rheumatism (EULAR) working group to develop HOA classification criteria, which involves a collaboration between US and European researchers that will redefine the disease for future studies. Most recently, she was involved in the ACR/Arthritis Foundation development of treatment guidelines for osteoarthritis.

    Outside of research, Dr. Ishimori practices as a rheumatologist with a local, national and international referral base. Dr. Ishimori has continued to work closely with primary care providers at the Saban Community Clinic (previously the Los Angeles Free Clinic) in partnership with their primary care providers with an interest in rheumatology as part of a “Rheumatology Champion” program, to expand access to rheumatologic care in that setting. This includes her monthly volunteer clinical activity at both the Saban Clinic and Venice Family Clinic, which serve safety net populations. Dr. Ishimori is also an active and critical component of the rheumatology fellowship training program and regularly works with rotating medical students, residents and fellows on the rheumatology teaching service and has worked with high school students and now helps administrate the Long Beach Polytechnic High School Research Enrichment program through the Cedars CTRC (PCI) for several years.

    Collapse Research 
    Collapse Research Activities and Funding
    Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE)
    NIH U01AR071077Feb 1, 2017 - Jan 31, 2023
    Role: Co-Investigator
    UCLA Clinical Translational Science Institute
    NIH UL1TR001881Jul 1, 2016 - May 31, 2021
    Role: Co-Investigator
    Evolving Adaptive and Effector Mechanisms from Pre-RA Through Established Disease
    NIH UH2AR067681Sep 24, 2014 - May 31, 2021
    Role: Co-Investigator
    The Genetics of Hand Osteoarthritis Study (GHOST)
    NIH K23AR056996Jun 1, 2009 - Mar 31, 2014
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Home-based virtual reality for chronic pain: protocol for an NIH-supported randomised-controlled trial. BMJ Open. 2021 06 15; 11(6):e050545. Birckhead B, Eberlein S, Alvarez G, Gale R, Dupuy T, Makaroff K, Fuller G, Liu X, Yu KS, Black JT, Ishimori M, Venuturupalli S, Tu J, Norris T, Tighiouart M, Ross L, McKelvey K, Vrahas M, Danovitch I, Spiegel B. PMID: 34130965.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    2. Repeated Spinal Mobility Measures and Their Association With Radiographic Damage in Ankylosing Spondylitis. ACR Open Rheumatol. 2021 May 27. Hwang MC, Lee M, Gensler LS, Ward MM, Brown MA, Learch TJ, Tahanan A, Rahbar MH, Ishimori M, Weisman MH, Reveille JD, PSOAS Study Investigators . PMID: 34042330.
      View in: PubMed   Mentions:
    3. Low levels of anti-cyclic citrullinated peptide (CCP) 3.1 associated with diseases other than rheumatoid arthritis. Medicine (Baltimore). 2021 Apr 23; 100(16):e25558. Son JJ, Ishimori M, Mirocha J, Weisman MH, Forbess LJ. PMID: 33879708.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Risk Factors for Spinal Structural Damage in a Chinese Cohort With Ankylosing Spondylitis. J Clin Rheumatol. 2020 Dec 24; Publish Ahead of Print. Kong W, Jefferies C, Learch TJ, Gan X, Zhu F, Zhang N, Jin D, Zhang Y, Tao Q, Yan X, Ishimori ML, Weisman MH. PMID: 33394829.
      View in: PubMed   Mentions:    Fields:    
    5. Chronic back pain in first-degree relatives (FDRs) of patients with ankylosing spondylitis: predictive value of HLA-B27 and persistence of inflammatory back pain over time. RMD Open. 2020 11; 6(3). Doughem K, Weisman MH, Ward MM, Gensler LS, Ishimori M, Tahanan A, Kung DC, Diekman L, Lee M, Rahbar MH, Reveille JD. PMID: 33243782.
      View in: PubMed   Mentions:
    6. Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model. Front Immunol. 2020; 11:554725. Tumurkhuu G, Chen S, Montano EN, Ercan Laguna D, De Los Santos G, Yu JM, Lane M, Yamashita M, Markman JL, Blanco LP, Kaplan MJ, Shimada K, Crother TR, Ishimori M, Wallace DJ, Jefferies CA, Arditi M. PMID: 33072095.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    7. The changing profile of ankylosing spondylitis in the biologic era. Clin Rheumatol. 2020 Sep; 39(9):2641-2651. Reveille JD, Lee M, Gensler LS, Ward MM, Hwang MC, Learch TJ, Tahanan A, Diekman L, Rahbar MH, Ishimori ML, Weisman MH. PMID: 32648102.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Examining Treatment Decision-Making Among Patients With Axial Spondyloarthritis: Insights From a Conjoint Analysis Survey. ACR Open Rheumatol. 2020 Jul; 2(7):391-400. Joo W, Almario CV, Ishimori M, Park Y, Jusufagic A, Noah B, Gensler LS, Venuturupalli RS, Kay J, Weisman MH, Spiegel BMR. PMID: 32519467.
      View in: PubMed   Mentions:
    9. Five-Year Follow-Up of Coronary Microvascular Dysfunction and Coronary Artery Disease in Systemic Lupus Erythematosus: Results From a Community-Based Lupus Cohort. Arthritis Care Res (Hoboken). 2020 07; 72(7):882-887. Sandhu VK, Wei J, Thomson LEJ, Berman DS, Schapira J, Wallace D, Weisman MH, Bairey Merz CN, Ishimori ML. PMID: 31058466.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Development of classification criteria for hand osteoarthritis: comparative analyses of persons with and without hand osteoarthritis. RMD Open. 2020 06; 6(2). Haugen IK, Felson DT, Abhishek A, Berenbaum F, Bierma-Zeinstra S, Borgen T, Herrero Beaumont G, Ishimori M, Jonsson H, Kroon FP, Maheu E, Ramonda R, Ritschl V, Stamm TA, van der Heijde D, Wittoek R, Greibrokk E, Smeets W, Kloppenburg M. PMID: 32584781.
      View in: PubMed   Mentions:
    11. Magnetic resonance multitasking for multidimensional assessment of cardiovascular system: Development and feasibility study on the thoracic aorta. Magn Reson Med. 2020 11; 84(5):2376-2388. Hu Z, Christodoulou AG, Wang N, Shaw JL, Song SS, Maya MM, Ishimori ML, Forbess LJ, Xiao J, Bi X, Han F, Li D, Fan Z. PMID: 32301164.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Longitudinal associations between depressive symptoms and clinical factors in ankylosing spondylitis patients: analysis from an observational cohort. Rheumatol Int. 2020 Jul; 40(7):1053-1061. Hwang MC, Lee MJ, Gensler LS, Ward MM, Brown MA, Eisen S, Learch TJ, Tahanan A, Rahbar MH, Ishimori ML, Weisman MH, Reveille JD. PMID: 32166439.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee. Arthritis Rheumatol. 2020 02; 72(2):220-233. Kolasinski SL, Neogi T, Hochberg MC, Oatis C, Guyatt G, Block J, Callahan L, Copenhaver C, Dodge C, Felson D, Gellar K, Harvey WF, Hawker G, Herzig E, Kwoh CK, Nelson AE, Samuels J, Scanzello C, White D, Wise B, Altman RD, DiRenzo D, Fontanarosa J, Giradi G, Ishimori M, Misra D, Shah AA, Shmagel AK, Thoma LM, Turgunbaev M, Turner AS, Reston J. PMID: 31908163.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    14. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee. Arthritis Care Res (Hoboken). 2020 02; 72(2):149-162. Kolasinski SL, Neogi T, Hochberg MC, Oatis C, Guyatt G, Block J, Callahan L, Copenhaver C, Dodge C, Felson D, Gellar K, Harvey WF, Hawker G, Herzig E, Kwoh CK, Nelson AE, Samuels J, Scanzello C, White D, Wise B, Altman RD, DiRenzo D, Fontanarosa J, Giradi G, Ishimori M, Misra D, Shah AA, Shmagel AK, Thoma LM, Turgunbaev M, Turner AS, Reston J. PMID: 31908149.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    15. Mock Recruitment for the Study of Antimalarials in an Incomplete Lupus Erythematosus Trial. Arthritis Care Res (Hoboken). 2019 11; 71(11):1425-1429. Karp DR, Chong BF, James JA, Arriens C, Ishimori M, Wallace DJ, Liao D, Olsen NJ. PMID: 30369087.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Researcher perspectives on embedding community stakeholders in T1-T2 research: A potential new model for full-spectrum translational research. J Clin Transl Sci. 2019 Jun; 3(2-3):120-124. George S, Vassar SD, Norris K, Coleman B, Gonzalez C, Ishimori M, Morris D, Mtume N, Shapiro MF, Lucas-Wright A, Brown AF. PMID: 31660235.
      View in: PubMed   Mentions:
    17. Patient Concerns and Perceptions Regarding Biologic Therapies in Ankylosing Spondylitis: Insights From a Large-Scale Survey of Social Media Platforms. Arthritis Care Res (Hoboken). 2019 02; 71(2):323-330. Dzubur E, Khalil C, Almario CV, Noah B, Minhas D, Ishimori M, Arnold C, Park Y, Kay J, Weisman MH, Spiegel BMR. PMID: 29781587.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Report from the Hand Osteoarthritis Working Group at OMERACT 2018: Update on Core Instrument Set Development. J Rheumatol. 2019 09; 46(9):1183-1187. Wittoek R, Kroon FPB, Kundakci B, Abhishek A, Haugen IK, Berenbaum F, Conaghan PG, Ishimori ML, Smeets W, van der Heijde D, Kloppenburg M. PMID: 30647176.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE): study protocol for a randomized controlled trial. Trials. 2018 Dec 20; 19(1):694. Olsen NJ, James JA, Arriens C, Ishimori ML, Wallace DJ, Kamen DL, Chong BF, Liao D, Chinchilli VM, Karp DR. PMID: 30572906.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    20. HLA class I and II alleles in susceptibility to ankylosing spondylitis. Ann Rheum Dis. 2019 01; 78(1):66-73. Reveille JD, Zhou X, Lee M, Weisman MH, Yi L, Gensler LS, Zou H, Ward MM, Ishimori ML, Learch TJ, He D, Rahbar MH, Wang J, Brown MA. PMID: 30341055.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    21. IL-16/miR-125a axis controls neutrophil recruitment in pristane-induced lung inflammation. JCI Insight. 2018 08 09; 3(15). Smith S, Wu PW, Seo JJ, Fernando T, Jin M, Contreras J, Montano EN, Gabhann JN, Cunningham K, Widaa A, McCarthy EM, Molloy ES, Kearns G, Murphy CC, Kong W, Björkbacka H, Kornfeld H, Forbess L, Venuturupalli S, Ishimori M, Wallace D, Weisman MH, Jefferies CA. PMID: 30089723.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    22. Causes and Predictors of Early Hospital Readmission in Systemic Lupus Erythematosus. J Rheumatol. 2018 07; 45(7):929-933. Nangit A, Lin C, Ishimori ML, Spiegel BMR, Weisman MH. PMID: 29657150.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Strong viral associations with SLE among Filipinos. Lupus Sci Med. 2017; 4(1):e000214. Vista ES, Weisman MH, Ishimori ML, Chen H, Bourn RL, Bruner BF, Hamijoyo L, Tanangunan RD, Gal NJ, Robertson JM, Harley JB, Guthridge JM, Navarra SV, James JA. PMID: 29214036.
      View in: PubMed   Mentions:
    24. MicroRNA-302d targets IRF9 to regulate the IFN-induced gene expression in SLE. J Autoimmun. 2017 May; 79:105-111. Smith S, Fernando T, Wu PW, Seo J, Ní Gabhann J, Piskareva O, McCarthy E, Howard D, O'Connell P, Conway R, Gallagher P, Molloy E, Stallings RL, Kearns G, Forbess L, Ishimori M, Venuturupalli S, Wallace D, Weisman M, Jefferies CA. PMID: 28318807.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    25. Role of psychosocial reserve capacity in anxiety and depression in patients with systemic lupus erythematosus. Int J Rheum Dis. 2018 Apr; 21(4):850-858. Zamora-Racaza G, Azizoddin DR, Ishimori ML, Ormseth SR, Wallace DJ, Penserga EG, Sumner L, Ayeroff J, Draper T, Nicassio PM, Weisman MH. PMID: 28261991.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features. Arthritis Rheumatol. 2017 03; 69(3):630-642. Munroe ME, Young KA, Kamen DL, Guthridge JM, Niewold TB, Costenbader KH, Weisman MH, Ishimori ML, Wallace DJ, Gilkeson GS, Karp DR, Harley JB, Norris JM, James JA. PMID: 27863174.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    27. Prevalence of resting-ECG abnormalities in systemic lupus erythematosus: a single-center experience. Clin Rheumatol. 2017 Jun; 36(6):1311-1316. Myung G, Forbess LJ, Ishimori ML, Chugh S, Wallace D, Weisman MH. PMID: 28238088.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus. Ann Rheum Dis. 2017 Jan; 76(1):153-158. Young KA, Munroe ME, Guthridge JM, Kamen DL, Niewold TB, Gilkeson GS, Weisman MH, Ishimori ML, Kelly J, Gaffney PM, Sivils KH, Lu R, Wallace DJ, Karp DR, Harley JB, James JA, Norris JM. PMID: 27283331.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    29. Chest pain in lupus patients: the emergency department experience. Clin Rheumatol. 2015 Nov; 34(11):1969-73. Modi M, Ishimori ML, Sandhu VK, Wallace DJ, Weisman MH. PMID: 25912215.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Systemic lupus erythematosus cardiomyopathy—a case series demonstrating a reversible form of left ventricular dysfunction. Echocardiography. 2014 May; 31(5):563-8. Ishimori ML, Agarwal M, Beigel R, Ng RK, Firooz N, Weisman MH, Siegel RJ. PMID: 25232571.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Microvascular angina: an underappreciated cause of SLE chest pain. J Rheumatol. 2013 May; 40(5):746-7. Ishimori ML, Anderson L, Weisman MH, Mehta PK, Bairey Merz CN, Wallace DJ. PMID: 23637384.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Disease-specific patient reported outcome tools for systemic lupus erythematosus. Semin Arthritis Rheum. 2012 Aug; 42(1):56-65. Jolly M, Pickard AS, Block JA, Kumar RB, Mikolaitis RA, Wilke CT, Rodby RA, Fogg L, Sequeira W, Utset TO, Cash TF, Moldovan I, Katsaros E, Nicassio P, Ishimori ML, Kosinsky M, Merrill JT, Weisman MH, Wallace DJ. PMID: 22480408.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    33. Subendocardial ischemia and myocarditis in systemic lupus erythematosus detected by cardiac magnetic resonance imaging. J Rheumatol. 2012 Feb; 39(2):448-50. Goykhman P, Mehta PK, Minissian M, Thomson LE, Berman DS, Ishimori ML, Wallace DJ, Weisman MH, Shufelt CL, Bairey Merz CN. PMID: 22298279.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    34. Disparities in renal replacement in lupus nephritis: current practice and future implications. Arthritis Care Res (Hoboken). 2011 Dec; 63(12):1639-41. Ishimori ML, Gudsoorkar V, Venuturupalli SR, Weisman MH. PMID: 22127964.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Myocardial ischemia in the absence of obstructive coronary artery disease in systemic lupus erythematosus. JACC Cardiovasc Imaging. 2011 Jan; 4(1):27-33. Ishimori ML, Martin R, Berman DS, Goykhman P, Shaw LJ, Shufelt C, Slomka PJ, Thomson LE, Schapira J, Yang Y, Wallace DJ, Weisman MH, Bairey Merz CN. PMID: 21232700.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    36. Heritability patterns in hand osteoarthritis: the role of osteophytes. Arthritis Res Ther. 2010; 12(5):R180. Ishimori ML, Altman RD, Cohen MJ, Cui J, Guo X, Rotter JI, Weisman MH. PMID: 20920163.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Sample stability and variability of B-cell subsets in blood from healthy subjects and patients with systemic lupus erythematosus. Cytometry B Clin Cytom. 2010 Jan; 78(1):49-58. Belouski SS, Wallace D, Weisman M, Ishimori M, Hendricks L, Zack D, Vincent M, Rasmussen E, Ferbas J, Chung J. PMID: 19670351.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    38. Use of pharmacogenetics, enzymatic phenotyping, and metabolite monitoring to guide treatment with azathioprine in patients with systemic lupus erythematosus. J Rheumatol. 2009 Jan; 36(1):89-95. Askanase AD, Wallace DJ, Weisman MH, Tseng CE, Bernstein L, Belmont HM, Seidman E, Ishimori M, Izmirly PM, Buyon JP. PMID: 19040311.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    39. Measurement of antinuclear antibodies by multiplex immunoassay: a prospective, multicenter clinical evaluation. J Rheumatol. 2007 May; 34(5):978-86. Moder KG, Wener MH, Weisman MH, Ishimori ML, Wallace DJ, Buckeridge DL, Homburger HA. PMID: 17407218.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    40. Posterior reversible encephalopathy syndrome: another manifestation of CNS SLE? Lupus. 2007; 16(6):436-43. Ishimori ML, Pressman BD, Wallace DJ, Weisman MH. PMID: 17664235.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    41. Ischemic stroke in a postpartum patient: understanding the epidemiology, pathogenesis, and outcome of Moyamoya disease. Semin Arthritis Rheum. 2006 Feb; 35(4):250-9. Ishimori ML, Cohen SN, Hallegua DS, Moser FG, Weisman MH. PMID: 16461070.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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