Andre Nel

Title(s)Professor, Medicine
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Use of a Nano-Enabled Platform for Pancreatic Cancer Immunotherapy
    NIH R01CA247666Jul 1, 2020 - Jun 30, 2025
    Role: Principal Investigator
    Toxicological Profiling of Engineered Nanomaterials (ENMs) in the MPS (RES)
    NIH U01ES027237Sep 1, 2016 - Aug 31, 2021
    Role: Principal Investigator
    UCLA Multifunctional Mesoporous Silica Nanoparticle Platform for Treatment of Pancreas Cancer
    NIH U01CA198846Sep 25, 2015 - Jul 31, 2021
    Role: Principal Investigator
    Carbon Nanotube Structure-Activity Relationships for Predictive Toxicology
    NIH R01ES022698Dec 9, 2013 - Oct 31, 2019
    Role: Principal Investigator
    Center for Nanobiology and Predictive Toxicology
    NIH U19ES019528Sep 24, 2010 - Apr 30, 2016
    Role: Principal Investigator
    Nanovalve Platform: Targeted, Controlled, Release of Anticancer Drugs
    NIH R01CA133697Jan 1, 2010 - Jun 30, 2015
    Role: Co-Principal Investigator
    Predictive Toxicological Paradigms to Establish Inhalation Toxicology Models
    NIH RC2ES018766Sep 30, 2009 - Jun 30, 2012
    Role: Principal Investigator
    Predictive Toxicological Paradigm for Chronic Nanoparticle Injury in the Lung
    NIH R01ES016746May 15, 2008 - Feb 29, 2020
    Role: Principal Investigator
    Development of methods and models for nanoparticle toxicity screening: Applicatio
    NIH R01ES015498Sep 30, 2006 - Jun 30, 2009
    Role: Principal Investigator
    Xenobiotics, Oxidative Stress and Allergic Inflammation
    NIH U19AI070453Jul 15, 2006 - Jun 30, 2012
    Role: Principal Investigator
    Atherogenic Effects of Ambient PM In Susceptible Animals
    NIH R01ES013432Sep 1, 2004 - Jul 31, 2010
    Role: Principal Investigator
    Proteomics of DEP-induced Oxidative Stress
    NIH R01ES012053Sep 10, 2002 - Jul 31, 2008
    Role: Principal Investigator
    Biological Analysis of Toxic DEP Chemicals
    NIH R01ES010553Feb 21, 2002 - Nov 30, 2008
    Role: Principal Investigator
    Lipids rafts in JNK and Nk-kB activation by TCR/CD28
    NIH R01AG014992Aug 1, 1998 - Apr 30, 2010
    Role: Principal Investigator
    MAPK CASCADES AND FUNCTION DECLINE OF AGED T CELLS
    NIH R03AG014763Aug 1, 1997 - Jul 31, 1999
    Role: Principal Investigator
    CYTOKINE AND GROWTH FACTOR PATHWAYS IN KAPOSIS SARCOMA
    NIH R01CA065329Jul 1, 1994 - Apr 30, 2000
    Role: Principal Investigator
    PKC AND TYROSINE KINASES SYNERGIZE IN T-CELL ACTIVATION
    NIH R01GM041576Sep 1, 1988 - Mar 31, 1997
    Role: Principal Investigator
    ALLERGY, IMMUNOLOGY &TRANSPLANTATION RESEARCH COMMITTEE
    NIH U09AI023260Jul 1, 1985 - Jun 30, 2006
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tanks and Truth. ACS Nano. 2022 Mar 22. Kotov NA, Akinwande D, Brinker CJ, Buriak JM, Chan WCW, Chen X, Chhowalla M, Chueh W, Glotzer SC, Gogotsi Y, Hersam MC, Ho D, Hu T, Javey A, Kagan CR, Kataoka K, Kim ID, Lee ST, Lee YH, Liz-Marzán LM, Millstone JE, Mulvaney P, Nel AE, Nordlander P, Parak WJ, Penner RM, Rogach AL, Salanne M, Schaak RE, Sood AK, Stevens M, Tsukruk V, Wee ATS, Voets I, Weil T, Weiss PS. PMID: 35315638.
      View in: PubMed   Mentions:    Fields:    
    2. Retraction of "Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway". ACS Nano. 2021 Jun 22; 15(6):10735. Lu J, Liu X, Liao YP, Wang X, Ahmed A, Jiang W, Ji Y, Meng H, Nel AE. PMID: 34018715; PMCID: PMC8887877.
      View in: PubMed   Mentions:    Fields:    
    3. Development of Facile and Versatile Platinum Drug Delivering Silicasome Nanocarriers for Efficient Pancreatic Cancer Chemo-Immunotherapy. Small. 2021 04; 17(14):e2005993. Liu X, Jiang J, Chang CH, Liao YP, Lodico JJ, Tang I, Zheng E, Qiu W, Lin M, Wang X, Ji Y, Mei KC, Nel AE, Meng H. PMID: 33682329; PMCID: PMC8035264.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    4. Combination Chemo-Immunotherapy for Pancreatic Cancer Using the Immunogenic Effects of an Irinotecan Silicasome Nanocarrier Plus Anti-PD-1. Adv Sci (Weinh). 2021 Mar; 8(6):2002147. Liu X, Jiang J, Liao YP, Tang I, Zheng E, Qiu W, Lin M, Wang X, Ji Y, Mei KC, Liu Q, Chang CH, Wainberg ZA, Nel AE, Meng H. PMID: 33747719; PMCID: PMC7967046.
      View in: PubMed   Mentions: 7     Fields:    
    5. Immune checkpoint inhibition in syngeneic mouse cancer models by a silicasome nanocarrier delivering a GSK3 inhibitor. Biomaterials. 2021 02; 269:120635. Allen SD, Liu X, Jiang J, Liao YP, Chang CH, Nel AE, Meng H. PMID: 33422940; PMCID: PMC7870571.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    6. Antigen- and Epitope-Delivering Nanoparticles Targeting Liver Induce Comparable Immunotolerance in Allergic Airway Disease and Anaphylaxis as Nanoparticle-Delivering Pharmaceuticals. ACS Nano. 2021 01 26; 15(1):1608-1626. Liu Q, Wang X, Liu X, Liao YP, Chang CH, Mei KC, Jiang J, Tseng S, Gochman G, Huang M, Thatcher Z, Li J, Allen SD, Lucido L, Xia T, Nel AE. PMID: 33351586; PMCID: PMC7943028.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    7. Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-immunotherapy in Multiple Solid Tumors. ACS Nano. 2020 10 27; 14(10):13343-13366. Mei KC, Liao YP, Jiang J, Chiang M, Khazaieli M, Liu X, Wang X, Liu Q, Chang CH, Zhang X, Li J, Ji Y, Melano B, Telesca D, Xia T, Meng H, Nel AE. PMID: 32940463; PMCID: PMC8023019.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    8. Nano as a Rosetta Stone: The Global Roles and Opportunities for Nanoscience and Nanotechnology. ACS Nano. 2019 10 22; 13(10):10853-10855. Zhao Y, Bai C, Brinker CJ, Chi L, Dawson KA, Gogotsi Y, Halas NJ, Lee ST, Lee T, Liz-Marzán L, Miller JF, Mitra S, Nel AE, Nordlander P, Parak WJ, Rowan A, Rogach AL, Rotello VM, Tang BZ, Wee ATS, Weiss PS. PMID: 31683413.
      View in: PubMed   Mentions: 2     Fields:    
    9. IL-4 subverts mycobacterial containment in Mycobacterium tuberculosis-infected human macrophages. Eur Respir J. 2019 08; 54(2). Pooran A, Davids M, Nel A, Shoko A, Blackburn J, Dheda K. PMID: 31097521.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    10. Nanoscience and Nanotechnology at UCLA. ACS Nano. 2019 06 25; 13(6):6127-6129. Khademhosseini A, Nel AE, Bunje H, DeSantis CJ, Andrews AM, Blaik RA, Gu Z, Meng H, Ozcan A, Tolbert SH, Xia T, Zink JI, Weiss PS. PMID: 31247733.
      View in: PubMed   Mentions:    Fields:    
    11. Use of Polymeric Nanoparticle Platform Targeting the Liver To Induce Treg-Mediated Antigen-Specific Immune Tolerance in a Pulmonary Allergen Sensitization Model. ACS Nano. 2019 04 23; 13(4):4778-4794. Liu Q, Wang X, Liu X, Kumar S, Gochman G, Ji Y, Liao YP, Chang CH, Situ W, Lu J, Jiang J, Mei KC, Meng H, Xia T, Nel AE. PMID: 30964276; PMCID: PMC6506187.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    12. Impact of weather and climate change with indoor and outdoor air quality in asthma: A Work Group Report of the AAAAI Environmental Exposure and Respiratory Health Committee. J Allergy Clin Immunol. 2019 05; 143(5):1702-1710. Poole JA, Barnes CS, Demain JG, Bernstein JA, Padukudru MA, Sheehan WJ, Fogelbach GG, Wedner J, Codina R, Levetin E, Cohn JR, Kagen S, Portnoy JM, Nel AE. PMID: 30826366.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    13. Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon Cancer. ACS Nano. 2019 01 22; 13(1):38-53. Liu X, Jiang J, Chan R, Ji Y, Lu J, Liao YP, Okene M, Lin J, Lin P, Chang CH, Wang X, Tang I, Zheng E, Qiu W, Wainberg ZA, Nel AE, Meng H. PMID: 30525443; PMCID: PMC6554030.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    14. Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway. ACS Nano. 2018 11 27; 12(11):11041-11061. Lu J, Liu X, Liao YP, Wang X, Ahmed A, Jiang W, Ji Y, Meng H, Nel AE. PMID: 30481959; PMCID: PMC6262474.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    15. Use of nano engineered approaches to overcome the stromal barrier in pancreatic cancer. Adv Drug Deliv Rev. 2018 05; 130:50-57. Meng H, Nel AE. PMID: 29958925; PMCID: PMC6554022.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    16. Helmuth Möhwald (1946-2018). ACS Nano. 2018 Apr 24; 12(4):3053-3055. Parak WJ, Chan WWC, Chhowalla M, Farokhzad O, Glotzer S, Gogotsi Y, Hammond PT, Hersam MC, Javey A, Kagan CR, Kataoka K, Khademhosseini A, Kotov NA, Lee ST, Lee YH, Li Y, Millstone J, Mulvaney PA, Nel AE, Nordlander PJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee ATS, Willson CG, Weiss PS. PMID: 29676563.
      View in: PubMed   Mentions:    Fields:    
    17. Surface Oxidation of Graphene Oxide Determines Membrane Damage, Lipid Peroxidation, and Cytotoxicity in Macrophages in a Pulmonary Toxicity Model. ACS Nano. 2018 02 27; 12(2):1390-1402. Li R, Guiney LM, Chang CH, Mansukhani ND, Ji Z, Wang X, Liao YP, Jiang W, Sun B, Hersam MC, Nel AE, Xia T. PMID: 29328670; PMCID: PMC5834379.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    18. Nanotechnology Strategies To Advance Outcomes in Clinical Cancer Care. ACS Nano. 2018 01 23; 12(1):24-43. Hartshorn CM, Bradbury MS, Lanza GM, Nel AE, Rao J, Wang AZ, Wiesner UB, Yang L, Grodzinski P. PMID: 29257865; PMCID: PMC6589353.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    19. Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression. Nat Commun. 2017 11 27; 8(1):1811. Lu J, Liu X, Liao YP, Salazar F, Sun B, Jiang W, Chang CH, Jiang J, Wang X, Wu AM, Meng H, Nel AE. PMID: 29180759; PMCID: PMC5703845.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    20. Our First and Next Decades at ACS Nano. ACS Nano. 2017 08 22; 11(8):7553-7555. Chan WCW, Chhowalla M, Glotzer S, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kataoka K, Khademhosseini A, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney P, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee ATS, Willson CG, Fernandez LE, Weiss PS. PMID: 28830059.
      View in: PubMed   Mentions:    Fields:    
    21. Major effect of transcytosis on nano drug delivery to pancreatic cancer. Mol Cell Oncol. 2017; 4(4):e1335273. Liu X, Jiang J, Nel AE, Meng H. PMID: 28868347; PMCID: PMC5540216.
      View in: PubMed   Mentions: 2  
    22. Advancing alternatives analysis: The role of predictive toxicology in selecting safer chemical products and processes. Integr Environ Assess Manag. 2017 Sep; 13(5):915-925. Malloy T, Zaunbrecher V, Beryt E, Judson R, Tice R, Allard P, Blake A, Cote I, Godwin H, Heine L, Kerzic P, Kostal J, Marchant G, McPartland J, Moran K, Nel A, Ogunseitan O, Rossi M, Thayer K, Tickner J, Whittaker M, Zarker K. PMID: 28247928.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    23. Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer. J Clin Invest. 2017 May 01; 127(5):2007-2018. Liu X, Lin P, Perrett I, Lin J, Liao YP, Chang CH, Jiang J, Wu N, Donahue T, Wainberg Z, Nel AE, Meng H. PMID: 28414297; PMCID: PMC5409788.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimals
    24. Diverse Applications of Nanomedicine. ACS Nano. 2017 03 28; 11(3):2313-2381. Pelaz B, Alexiou C, Alvarez-Puebla RA, Alves F, Andrews AM, Ashraf S, Balogh LP, Ballerini L, Bestetti A, Brendel C, Bosi S, Carril M, Chan WC, Chen C, Chen X, Chen X, Cheng Z, Cui D, Du J, Dullin C, Escudero A, Feliu N, Gao M, George M, Gogotsi Y, Grünweller A, Gu Z, Halas NJ, Hampp N, Hartmann RK, Hersam MC, Hunziker P, Jian J, Jiang X, Jungebluth P, Kadhiresan P, Kataoka K, Khademhosseini A, Kopecek J, Kotov NA, Krug HF, Lee DS, Lehr CM, Leong KW, Liang XJ, Ling Lim M, Liz-Marzán LM, Ma X, Macchiarini P, Meng H, Möhwald H, Mulvaney P, Nel AE, Nie S, Nordlander P, Okano T, Oliveira J, Park TH, Penner RM, Prato M, Puntes V, Rotello VM, Samarakoon A, Schaak RE, Shen Y, Sjöqvist S, Skirtach AG, Soliman MG, Stevens MM, Sung HW, Tang BZ, Tietze R, Udugama BN, VanEpps JS, Weil T, Weiss PS, Willner I, Wu Y, Yang L, Yue Z, Zhang Q, Zhang Q, Zhang XE, Zhao Y, Zhou X, Parak WJ. PMID: 28290206; PMCID: PMC5371978.
      View in: PubMed   Mentions: 215     Fields:    Translation:HumansAnimals
    25. Policy reforms to update chemical safety testing. Science. 2017 Mar 10; 355(6329):1016-1018. Nel AE, Malloy TF. PMID: 28280165.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    26. Nanoscience and Nanotechnology Cross Borders. ACS Nano. 2017 02 28; 11(2):1123-1126. Khademhosseini A, Chan WW, Chhowalla M, Glotzer SC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, Nel AE, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Brinker J, Chen X, Chi L, Crommie M, Dekker C, Farokhzad O, Gerber C, Ginger DS, Irvine DJ, Kiessling LL, Kostarelos K, Landes C, Lee T, Leggett GJ, Liang XJ, Liz-Marzán L, Millstone J, Odom TW, Ozcan A, Prato M, Rao CN, Sailor MJ, Weiss E, Weiss PS. PMID: 28199099.
      View in: PubMed   Mentions:    Fields:    
    27. Safe-by-Design CuO Nanoparticles via Fe-Doping, Cu-O Bond Length Variation, and Biological Assessment in Cells and Zebrafish Embryos. ACS Nano. 2017 01 24; 11(1):501-515. Naatz H, Lin S, Li R, Jiang W, Ji Z, Chang CH, Köser J, Thöming J, Xia T, Nel AE, Mädler L, Pokhrel S. PMID: 28026936; PMCID: PMC5824973.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    28. Nanoscience and Nanotechnology Impacting Diverse Fields of Science, Engineering, and Medicine. ACS Nano. 2016 12 27; 10(12):10615-10617. Chan WW, Chhowalla M, Glotzer S, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Khademhosseini A, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, Fernandez LE, Weiss PS. PMID: 28024354.
      View in: PubMed   Mentions: 3     Fields:    
    29. Identification and Optimization of Carbon Radicals on Hydrated Graphene Oxide for Ubiquitous Antibacterial Coatings. ACS Nano. 2016 12 27; 10(12):10966-10980. Li R, Mansukhani ND, Guiney LM, Ji Z, Zhao Y, Chang CH, French CT, Miller JF, Hersam MC, Nel AE, Xia T. PMID: 28024366; PMCID: PMC5612796.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    30. Correction to Use of a Lipid-Coated Mesoporous Silica Nanoparticle Platform for Synergistic Gemcitabine and Paclitaxel Delivery to Human Pancreatic Cancer in Mice. ACS Nano. 2016 06 28; 10(6):6416. Meng H, Wang M, Liu H, Liu X, Situ A, Wu B, Ji Z, Chang CH, Nel AE. PMID: 27199284; PMCID: PMC4928141.
      View in: PubMed   Mentions: 4     Fields:    
    31. Irinotecan Delivery by Lipid-Coated Mesoporous Silica Nanoparticles Shows Improved Efficacy and Safety over Liposomes for Pancreatic Cancer. ACS Nano. 2016 Feb 23; 10(2):2702-15. Liu X, Situ A, Kang Y, Villabroza KR, Liao Y, Chang CH, Donahue T, Nel AE, Meng H. PMID: 26835979; PMCID: PMC4851343.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    32. Grand Plans for Nano. ACS Nano. 2015 Dec 22; 9(12):11503-5. Chan WW, Glotzer S, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Khademhosseini A, Kotov NA, Lee ST, Möhwald H, Mulvaney PA, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, Tierney HL, Weiss PS. PMID: 26689337.
      View in: PubMed   Mentions: 1     Fields:    
    33. Big Roles for Nanocenters. ACS Nano. 2015 Sep 22; 9(9):8639-40. Hersam MC, Lee ST, Nel AE, Rogach A, Buriak JM, Weiss PS. PMID: 26391441.
      View in: PubMed   Mentions:    Fields:    
    34. Evaluation of Toxicity Ranking for Metal Oxide Nanoparticles via an in Vitro Dosimetry Model. ACS Nano. 2015 Sep 22; 9(9):9303-13. Liu R, Liu HH, Ji Z, Chang CH, Xia T, Nel AE, Cohen Y. PMID: 26284985.
      View in: PubMed   Mentions: 22     Fields:    
    35. Grand Challenges for Nanoscience and Nanotechnology. ACS Nano. 2015 Jul 28; 9(7):6637-40. Parak WJ, Nel AE, Weiss PS. PMID: 26192457.
      View in: PubMed   Mentions: 2     Fields:    
    36. Cu Nanoparticles Have Different Impacts in Escherichia coli and Lactobacillus brevis than Their Microsized and Ionic Analogues. ACS Nano. 2015 Jul 28; 9(7):7215-25. Kaweeteerawat C, Chang CH, Roy KR, Liu R, Li R, Toso D, Fischer H, Ivask A, Ji Z, Zink JI, Zhou ZH, Chanfreau GF, Telesca D, Cohen Y, Holden PA, Nel AE, Godwin HA. PMID: 26168153; PMCID: PMC5698005.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    37. Where Are We Heading in Nanotechnology Environmental Health and Safety and Materials Characterization? ACS Nano. 2015 Jun 23; 9(6):5627-30. Nel AE, Parak WJ, Chan WC, Xia T, Hersam MC, Brinker CJ, Zink JI, Pinkerton KE, Baer DR, Weiss PS. PMID: 26100220.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    38. Mammalian Cells Exhibit a Range of Sensitivities to Silver Nanoparticles that are Partially Explicable by Variations in Antioxidant Defense and Metallothionein Expression. Small. 2015 Aug; 11(31):3797-805. Zhang H, Wang X, Wang M, Li L, Chang CH, Ji Z, Xia T, Nel AE. PMID: 25930061; PMCID: PMC4537384.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    39. Use of a lipid-coated mesoporous silica nanoparticle platform for synergistic gemcitabine and paclitaxel delivery to human pancreatic cancer in mice. ACS Nano. 2015; 9(4):3540-57. Meng H, Wang M, Liu H, Liu X, Situ A, Wu B, Ji Z, Chang CH, Nel AE. PMID: 25776964; PMCID: PMC4415452.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    40. Nanomaterial categorization for assessing risk potential to facilitate regulatory decision-making. ACS Nano. 2015; 9(4):3409-17. Godwin H, Nameth C, Avery D, Bergeson LL, Bernard D, Beryt E, Boyes W, Brown S, Clippinger AJ, Cohen Y, Doa M, Hendren CO, Holden P, Houck K, Kane AB, Klaessig F, Kodas T, Landsiedel R, Lynch I, Malloy T, Miller MB, Muller J, Oberdorster G, Petersen EJ, Pleus RC, Sayre P, Stone V, Sullivan KM, Tentschert J, Wallis P, Nel AE. PMID: 25791861.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimals
    41. Enhancing the imaging and biosafety of upconversion nanoparticles through phosphonate coating. ACS Nano. 2015 Mar 24; 9(3):3293-306. Li R, Ji Z, Dong J, Chang CH, Wang X, Sun B, Wang M, Liao YP, Zink JI, Nel AE, Xia T. PMID: 25727446; PMCID: PMC4415359.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    42. Comparative reevaluation of FASP and enhanced FASP methods by LC-MS/MS. J Proteome Res. 2015 Mar 06; 14(3):1637-42. Nel AJ, Garnett S, Blackburn JM, Soares NC. PMID: 25619111.
      View in: PubMed   Mentions: 17     Fields:    
    43. A year for nanoscience. ACS Nano. 2014 Dec 23; 8(12):11901-3. Chan WC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Khademhosseini A, Kotov NA, Lee ST, Möhwald H, Mulvaney PA, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, Weiss PS. PMID: 25533169.
      View in: PubMed   Mentions:    Fields:    
    44. Interference in autophagosome fusion by rare earth nanoparticles disrupts autophagic flux and regulation of an interleukin-1β producing inflammasome. ACS Nano. 2014 Oct 28; 8(10):10280-92. Li R, Ji Z, Qin H, Kang X, Sun B, Wang M, Chang CH, Wang X, Zhang H, Zou H, Nel AE, Xia T. PMID: 25251502; PMCID: PMC4213039.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    45. Association rule mining of cellular responses induced by metal and metal oxide nanoparticles. Analyst. 2014 Mar 07; 139(5):943-53. Liu R, France B, George S, Rallo R, Zhang H, Xia T, Nel AE, Bradley K, Cohen Y. PMID: 24260774.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    46. Surface interactions with compartmentalized cellular phosphates explain rare earth oxide nanoparticle hazard and provide opportunities for safer design. ACS Nano. 2014 Feb 25; 8(2):1771-83. Li R, Ji Z, Chang CH, Dunphy DR, Cai X, Meng H, Zhang H, Sun B, Wang X, Dong J, Lin S, Wang M, Liao YP, Brinker CJ, Nel A, Xia T. PMID: 24417322; PMCID: PMC3988685.
      View in: PubMed   Mentions: 51     Fields:    Translation:Cells
    47. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014 Jan; 5(1):35-41. Heber D, Li Z, Garcia-Lloret M, Wong AM, Lee TY, Thames G, Krak M, Zhang Y, Nel A. PMID: 24287881; PMCID: PMC8754169.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCTClinical Trials
    48. Two-wave nanotherapy to target the stroma and optimize gemcitabine delivery to a human pancreatic cancer model in mice. ACS Nano. 2013 Nov 26; 7(11):10048-65. Meng H, Zhao Y, Dong J, Xue M, Lin YS, Ji Z, Mai WX, Zhang H, Chang CH, Brinker CJ, Zink JI, Nel AE. PMID: 24143858; PMCID: PMC3878438.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    49. Be critical but fair. ACS Nano. 2013 Oct 22; 7(10):8313-6. Parak WJ, Chan WC, Hafner JH, Hammond PT, Hersam MC, Javey A, Khademhosseini A, Kotov NA, Mulvaney P, Nel AE, Nordlander PJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, Weiss PS. PMID: 24143923.
      View in: PubMed   Mentions: 2     Fields:    
    50. Nanocenter directors gather from around the world. ACS Nano. 2013 Sep 24; 7(9):7437-8. Mulvaney P, Nel AE, Rogach A, Weiss PS. PMID: 24490873.
      View in: PubMed   Mentions:    Fields:    
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    55. Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo. ACS Nano. 2013 Feb 26; 7(2):994-1005. Meng H, Mai WX, Zhang H, Xue M, Xia T, Lin S, Wang X, Zhao Y, Ji Z, Zink JI, Nel AE. PMID: 23289892; PMCID: PMC3620006.
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    56. Real-time electrical detection of nitric oxide in biological systems with sub-nanomolar sensitivity. Nat Commun. 2013; 4:2225. Jiang S, Cheng R, Wang X, Xue T, Liu Y, Nel A, Huang Y, Duan X. PMID: 23887829.
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    60. Nanomaterial toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput screening. Acc Chem Res. 2013 Mar 19; 46(3):607-21. Nel A, Xia T, Meng H, Wang X, Lin S, Ji Z, Zhang H. PMID: 22676423; PMCID: PMC4034475.
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    62. Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials. PLoS One. 2012; 7(4):e35014. Liu R, Lin S, Rallo R, Zhao Y, Damoiseaux R, Xia T, Lin S, Nel A, Cohen Y. PMID: 22506062; PMCID: PMC3323610.
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    63. Targeted intracellular delivery of antituberculosis drugs to Mycobacterium tuberculosis-infected macrophages via functionalized mesoporous silica nanoparticles. Antimicrob Agents Chemother. 2012 May; 56(5):2535-45. Clemens DL, Lee BY, Xue M, Thomas CR, Meng H, Ferris D, Nel AE, Zink JI, Horwitz MA. PMID: 22354311; PMCID: PMC3346638.
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    64. Development of Pharmaceutically Adapted Mesoporous Silica Nanoparticles Platform. J Phys Chem Lett. 2012 Feb 02; 3(3):358-9. Meng H, Xue M, Zink JI, Nel AE. PMID: 26285851.
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    66. Feasibility of biomarker studies for engineered nanoparticles: what can be learned from air pollution research. J Occup Environ Med. 2011 Jun; 53(6 Suppl):S74-9. Li N, Nel AE. PMID: 21654422; PMCID: PMC3163229.
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    67. Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism. ACS Nano. 2011 Jun 28; 5(6):4434-47. Meng H, Yang S, Li Z, Xia T, Chen J, Ji Z, Zhang H, Wang X, Lin S, Huang C, Zhou ZH, Zink JI, Nel AE. PMID: 21563770; PMCID: PMC3125420.
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    68. Use of size and a copolymer design feature to improve the biodistribution and the enhanced permeability and retention effect of doxorubicin-loaded mesoporous silica nanoparticles in a murine xenograft tumor model. ACS Nano. 2011 May 24; 5(5):4131-44. Meng H, Xue M, Xia T, Ji Z, Tarn DY, Zink JI, Nel AE. PMID: 21524062; PMCID: PMC3905975.
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    69. Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells. ACS Nano. 2011 Apr 26; 5(4):2756-2769. Zhang H, Xia T, Meng H, Xue M, George S, Ji Z, Wang X, Liu R, Wang M, France B, Rallo R, Damoiseaux R, Cohen Y, Bradley KA, Zink JI, Nel AE. PMID: 21366263; PMCID: PMC3896548.
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    70. Nanomaterials in the environment: from materials to high-throughput screening to organisms. ACS Nano. 2011 Jan 25; 5(1):13-20. Thomas CR, George S, Horst AM, Ji Z, Miller RJ, Peralta-Videa JR, Xia T, Pokhrel S, Mädler L, Gardea-Torresdey JL, Holden PA, Keller AA, Lenihan HS, Nel AE, Zink JI. PMID: 21261306.
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    71. Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. ACS Nano. 2011 Feb 22; 5(2):1223-35. Xia T, Zhao Y, Sager T, George S, Pokhrel S, Li N, Schoenfeld D, Meng H, Lin S, Wang X, Wang M, Ji Z, Zink JI, Mädler L, Castranova V, Lin S, Nel AE. PMID: 21250651; PMCID: PMC3900638.
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    72. Self-organizing map analysis of toxicity-related cell signaling pathways for metal and metal oxide nanoparticles. Environ Sci Technol. 2011 Feb 15; 45(4):1695-702. Rallo R, France B, Liu R, Nair S, George S, Damoiseaux R, Giralt F, Nel A, Bradley K, Cohen Y. PMID: 21250674; PMCID: PMC4418424.
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    73. Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles by pH-sensitive nanovalves. J Am Chem Soc. 2010 Sep 15; 132(36):12690-7. Meng H, Xue M, Xia T, Zhao YL, Tamanoi F, Stoddart JF, Zink JI, Nel AE. PMID: 20718462; PMCID: PMC3116646.
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    74. Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line. ACS Nano. 2010 Aug 24; 4(8):4539-50. Meng H, Liong M, Xia T, Li Z, Ji Z, Zink JI, Nel AE. PMID: 20731437; PMCID: PMC3899722.
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    75. Urticaria associated with necrotic uterine leiomyomas infected with salmonella. Obstet Gynecol. 2010 Aug; 116 Suppl 2:491-493. Tachdjian R, Tourangeau L, Schneider JL, Nel A. PMID: 20664429.
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    76. Ambient ultrafine particles provide a strong adjuvant effect in the secondary immune response: implication for traffic-related asthma flares. Am J Physiol Lung Cell Mol Physiol. 2010 Sep; 299(3):L374-83. Li N, Harkema JR, Lewandowski RP, Wang M, Bramble LA, Gookin GR, Ning Z, Kleinman MT, Sioutas C, Nel AE. PMID: 20562226; PMCID: PMC2951067.
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    77. Adjuvant effects of ambient particulate matter monitored by proteomics of bronchoalveolar lavage fluid. Proteomics. 2010 Feb; 10(3):520-31. Kang X, Li N, Wang M, Boontheung P, Sioutas C, Harkema JR, Bramble LA, Nel AE, Loo JA. PMID: 20029843; PMCID: PMC3021977.
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    78. Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs. ACS Nano. 2009 Oct 27; 3(10):3273-86. Xia T, Kovochich M, Liong M, Meng H, Kabehie S, George S, Zink JI, Nel AE. PMID: 19739605; PMCID: PMC3900639.
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    79. Particulate matter and atherosclerosis: role of particle size, composition and oxidative stress. Part Fibre Toxicol. 2009 Sep 18; 6:24. Araujo JA, Nel AE. PMID: 19761620; PMCID: PMC2761850.
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    81. Comparative toxicity of C60 aggregates toward mammalian cells: role of tetrahydrofuran (THF) decomposition. Environ Sci Technol. 2009 Aug 15; 43(16):6378-84. Kovochich M, Espinasse B, Auffan M, Hotze EM, Wessel L, Xia T, Nel AE, Wiesner MR. PMID: 19746740; PMCID: PMC3971833.
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    82. A predictive toxicological paradigm for the safety assessment of nanomaterials. ACS Nano. 2009 Jul 28; 3(7):1620-7. Meng H, Xia T, George S, Nel AE. PMID: 21452863.
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    83. The impact of air pollutants as an adjuvant for allergic sensitization and asthma. Curr Allergy Asthma Rep. 2009 Jul; 9(4):327-33. Viera L, Chen K, Nel A, Lloret MG. PMID: 19656481.
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    84. Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater. 2009 Jul; 8(7):543-57. Nel AE, Mädler L, Velegol D, Xia T, Hoek EM, Somasundaran P, Klaessig F, Castranova V, Thompson M. PMID: 19525947.
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    86. The adjuvant effect of ambient particulate matter is closely reflected by the particulate oxidant potential. Environ Health Perspect. 2009 Jul; 117(7):1116-23. Li N, Wang M, Bramble LA, Schmitz DA, Schauer JJ, Sioutas C, Harkema JR, Nel AE. PMID: 19654922; PMCID: PMC2717139.
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    87. Mesostructured Silica for Optical Functionality, Nanomachines, and Drug Delivery. J Am Ceram Soc. 2009 Jan 01; 92(s1):s2-s10. Klichko Y, Liong M, Choi E, Angelos S, Nel AE, Stoddart JF, Tamanoi F, Zink JI. PMID: 19834571; PMCID: PMC2761636.
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    89. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano. 2008 Oct 28; 2(10):2121-34. Xia T, Kovochich M, Liong M, Mädler L, Gilbert B, Shi H, Yeh JI, Zink JI, Nel AE. PMID: 19206459; PMCID: PMC3959800.
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    90. Innate immune responses during respiratory tract infection with a bacterial pathogen induce allergic airway sensitization. J Allergy Clin Immunol. 2008 Sep; 122(3):595-602.e5. Schröder NW, Crother TR, Naiki Y, Chen S, Wong MH, Yilmaz A, Slepenkin A, Schulte D, Alsabeh R, Doherty TM, Peterson E, Nel AE, Arditi M. PMID: 18774395; PMCID: PMC3052793.
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    91. Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery. ACS Nano. 2008 May; 2(5):889-96. Liong M, Lu J, Kovochich M, Xia T, Ruehm SG, Nel AE, Tamanoi F, Zink JI. PMID: 19206485; PMCID: PMC2751731.
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    92. T-cell effector pathways in allergic diseases: transcriptional mechanisms and therapeutic targets. J Allergy Clin Immunol. 2008 Apr; 121(4):812-23; quiz 824-5. Chatila TA, Li N, Garcia-Lloret M, Kim HJ, Nel AE. PMID: 18395547.
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    93. Nrf2 activation by sulforaphane restores the age-related decrease of T(H)1 immunity: role of dendritic cells. J Allergy Clin Immunol. 2008 May; 121(5):1255-1261.e7. Kim HJ, Barajas B, Wang M, Nel AE. PMID: 18325578; PMCID: PMC3897785.
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    95. Importance of oxidative stress in the pathogenesis and treatment of asthma. Curr Opin Allergy Clin Immunol. 2008 Feb; 8(1):49-56. Riedl MA, Nel AE. PMID: 18188018.
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    96. Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress. Circ Res. 2008 Mar 14; 102(5):589-96. Araujo JA, Barajas B, Kleinman M, Wang X, Bennett BJ, Gong KW, Navab M, Harkema J, Sioutas C, Lusis AJ, Nel AE. PMID: 18202315; PMCID: PMC3014059.
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    97. Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. ACS Nano. 2008 Jan; 2(1):85-96. Xia T, Kovochich M, Liong M, Zink JI, Nel AE. PMID: 19206551.
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    98. Pro-oxidative DEP chemicals induce heat shock proteins and an unfolding protein response in a bronchial epithelial cell line as determined by DIGE analysis. Proteomics. 2007 Nov; 7(21):3906-18. Jung EJ, Avliyakulov NK, Boontheung P, Loo JA, Nel AE. PMID: 17922515.
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    102. Impairment of mitochondrial function by particulate matter (PM) and their toxic components: implications for PM-induced cardiovascular and lung disease. Front Biosci. 2007 Jan 01; 12:1238-46. Xia T, Kovochich M, Nel AE. PMID: 17127377.
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    103. Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells. Genome Biol. 2007; 8(7):R149. Gong KW, Zhao W, Li N, Barajas B, Kleinman M, Sioutas C, Horvath S, Lusis AJ, Nel A, Araujo JA. PMID: 17655762; PMCID: PMC2323217.
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    104. Pro-oxidative diesel exhaust particle chemicals inhibit LPS-induced dendritic cell responses involved in T-helper differentiation. J Allergy Clin Immunol. 2006 Aug; 118(2):455-65. Chan RC, Wang M, Li N, Yanagawa Y, Onoé K, Lee JJ, Nel AE. PMID: 16890772.
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    106. Tracheobronchial particle dose considerations for in vitro toxicology studies. Toxicol Sci. 2006 Jul; 92(1):126-32. Phalen RF, Oldham MJ, Nel AE. PMID: 16597657.
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    108. Toxic potential of materials at the nanolevel. Science. 2006 Feb 03; 311(5761):622-7. Nel A, Xia T, Mädler L, Li N. PMID: 16456071.
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    109. Role of the Nrf2-mediated signaling pathway as a negative regulator of inflammation: implications for the impact of particulate pollutants on asthma. Antioxid Redox Signal. 2006 Jan-Feb; 8(1-2):88-98. Li N, Nel AE. PMID: 16487041.
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    122. Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages. J Immunol. 2002 Oct 15; 169(8):4531-41. Li N, Wang M, Oberley TD, Sempf JM, Nel AE. PMID: 12370390.
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    123. CD40-mediated p38 mitogen-activated protein kinase activation is required for immunoglobulin class switch recombination to IgE. J Allergy Clin Immunol. 2002 Sep; 110(3):421-8. Zhang K, Zhang L, Zhu D, Bae D, Nel A, Saxon A. PMID: 12209089.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    124. T-cell activation through the antigen receptor. Part 2: role of signaling cascades in T-cell differentiation, anergy, immune senescence, and development of immunotherapy. J Allergy Clin Immunol. 2002 Jun; 109(6):901-15. Nel AE, Slaughter N. PMID: 12063516.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    125. T-cell activation through the antigen receptor. Part 1: signaling components, signaling pathways, and signal integration at the T-cell antigen receptor synapse. J Allergy Clin Immunol. 2002 May; 109(5):758-70. Nel AE. PMID: 11994696.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    126. Use of a stratified oxidative stress model to study the biological effects of ambient concentrated and diesel exhaust particulate matter. Inhal Toxicol. 2002 May; 14(5):459-86. Li N, Kim S, Wang M, Froines J, Sioutas C, Nel A. PMID: 12028803.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    127. Protein kinase D is a downstream target of protein kinase Ctheta. Biochem Biophys Res Commun. 2002 Mar 01; 291(3):444-52. Yuan J, Bae D, Cantrell D, Nel AE, Rozengurt E. PMID: 11855809.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    128. Thiol antioxidants inhibit the adjuvant effects of aerosolized diesel exhaust particles in a murine model for ovalbumin sensitization. J Immunol. 2002 Mar 01; 168(5):2560-7. Whitekus MJ, Li N, Zhang M, Wang M, Horwitz MA, Nelson SK, Horwitz LD, Brechun N, Diaz-Sanchez D, Nel AE. PMID: 11859152.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
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