William C Parks

Title(s)Professor, Medicine
SchoolMedicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Control of Macrophage Activation in Lung Disease
    NIH R01HL141078Apr 1, 2018 - Mar 31, 2022
    Role: Principal Investigator
    Graduate Program in Biomedical Sciences and Translational Medicine
    NIH T32GM118288Jul 1, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Role of MMP10 in Macrophage Activation
    NIH R56HL128995Sep 8, 2015 - Aug 31, 2016
    Role: Principal Investigator
    MMP10 Control of Macrophage Activation in COPD
    NIH R01HL089455Jan 1, 2011 - Feb 28, 2015
    Role: Principal Investigator
    Airway Metalloproteinases in Mucosal Immunity
    NIH R21AI083487Jun 5, 2009 - May 31, 2012
    Role: Principal Investigator
    American Society fo Matrix Biology 2008
    NIH R13AR056907Nov 25, 2008 - Jun 30, 2009
    Role: Principal Investigator
    Epithelial control of Neutrophil Activation
    NIH R01HL082658Jun 1, 2007 - Sep 30, 2012
    Role: Principal Investigator
    Epithelial MMPs in Airway Repair
    NIH R01HL077555Jul 1, 2004 - Jun 30, 2010
    Role: Principal Investigator
    Conference--2003 Tissue Repair And Regeneration
    NIH R13AR050005Jun 1, 2003 - May 31, 2004
    Role: Principal Investigator
    Regulation of Vascular Wall Extracellular Matrix
    NIH R01HL072554Apr 1, 2003 - Mar 31, 2007
    Role: Principal Investigator
    BIOLOGY OF THE CUTANEOUS EPITHELIUM
    NIH P01AR045254May 10, 1998 - Mar 31, 2004
    Role: Principal Investigator
    1997 GORDON CONFERENCE ON ELASTIN AND ELASTIC TISSUE
    NIH R13HL058443Jul 10, 1997 - Jun 30, 1998
    Role: Principal Investigator
    POSTTRANSCRIPTIONAL REGULATION OF TROPOELASTIN EXPRESSIO
    NIH R01HL048762Sep 30, 1992 - Aug 31, 2003
    Role: Principal Investigator
    CHARACTERIZATION OF TROPOELASTIN ISOFORMS
    NIH R29HL041040Jul 1, 1988 - Dec 31, 1993
    Role: Principal Investigator
    Dermatology Training Grant
    NIH T32AR007284Jul 1, 1978 - Apr 30, 2010
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Macrophages in Lung Repair and Fibrosis. Results Probl Cell Differ. 2024; 74:257-290. Jannini-Sá YAP, Creyns B, Hogaboam CM, Parks WC, Hohmann MS. PMID: 39406909.
      View in: PubMed   Mentions:
    2. Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection. Nat Commun. 2023 09 19; 14(1):5814. Beppu AK, Zhao J, Yao C, Carraro G, Israely E, Coelho AL, Drake K, Hogaboam CM, Parks WC, Kolls JK, Stripp BR. PMID: 37726288; PMCID: PMC10509177.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    3. Senescence of alveolar epithelial progenitor cells: a critical driver of lung fibrosis. Am J Physiol Cell Physiol. 2023 08 01; 325(2):C483-C495. Parimon T, Chen P, Stripp BR, Liang J, Jiang D, Noble PW, Parks WC, Yao C. PMID: 37458437; PMCID: PMC10511168.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    4. Sulfated motifs in heparan sulfate inhibit Streptococcus pneumoniae adhesion onto fibronectin and attenuate corneal infection. Proteoglycan Res. 2023 Jul 01; 1(3). Hayashida A, Saeed HN, Zhang F, Song Y, Liu J, Parks WC, Bispo PJM, Park PW. PMID: 38957622; PMCID: PMC11218895.
      View in: PubMed   Mentions: 2  
    5. Reciprocal interactions between alveolar progenitor dysfunction and aging promote lung fibrosis. Elife. 2023 06 14; 12. Liang J, Huang G, Liu X, Liu N, Taghavifar F, Dai K, Yao C, Deng N, Wang Y, Chen P, Hogaboam C, Stripp BR, Parks WC, Noble PW, Jiang D. PMID: 37314162; PMCID: PMC10292844.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    6. A compensatory RNase E variation increases Iron Piracy and Virulence in multidrug-resistant Pseudomonas aeruginosa during Macrophage infection. PLoS Pathog. 2023 04; 19(4):e1010942. Vaillancourt M, Galdino ACM, Limsuwannarot SP, Celedonio D, Dimitrova E, Broerman M, Bresee C, Doi Y, Lee JS, Parks WC, Jorth P. PMID: 37027441; PMCID: PMC10115287.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    7. The dynamic roles of the bladder tumour microenvironment. Nat Rev Urol. 2022 09; 19(9):515-533. Lee YC, Lam HM, Rosser C, Theodorescu D, Parks WC, Chan KS. PMID: 35764795; PMCID: PMC10112172.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    8. The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis. J Clin Invest. 2022 06 01; 132(11). Liang J, Huang G, Liu X, Taghavifar F, Liu N, Wang Y, Deng N, Yao C, Xie T, Kulur V, Dai K, Burman A, Rowan SC, Weigt SS, Belperio J, Stripp B, Parks WC, Jiang D, Noble PW. PMID: 35389887; PMCID: PMC9151700.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    9. Abnormal respiratory progenitors in fibrotic lung injury. Stem Cell Res Ther. 2022 02 07; 13(1):64. Xie T, Lynn H, Parks WC, Stripp B, Chen P, Jiang D, Noble PW. PMID: 35130980; PMCID: PMC8822870.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    10. Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF. JCI Insight. 2021 06 08; 6(11). Hohmann MS, Habiel DM, Espindola MS, Huang G, Jones I, Narayanan R, Coelho AL, Oldham JM, Noth I, Ma SF, Kurkciyan A, McQualter JL, Carraro G, Stripp B, Chen P, Jiang D, Noble PW, Parks W, Woronicz J, Yarranton G, Murray LA, Hogaboam CM. PMID: 33945505; PMCID: PMC8262321.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    11. Categorization of lung mesenchymal cells in development and fibrosis. iScience. 2021 Jun 25; 24(6):102551. Liu X, Rowan SC, Liang J, Yao C, Huang G, Deng N, Xie T, Wu D, Wang Y, Burman A, Parimon T, Borok Z, Chen P, Parks WC, Hogaboam CM, Weigt SS, Belperio J, Stripp BR, Noble PW, Jiang D. PMID: 34151224; PMCID: PMC8188567.
      View in: PubMed   Mentions: 36  
    12. Differential Responses to Targeting Matrix Metalloproteinase 9 in Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2021 02 15; 203(4):458-470. Espindola MS, Habiel DM, Coelho AL, Stripp B, Parks WC, Oldham J, Martinez FJ, Noth I, Lopez D, Mikels-Vigdal A, Smith V, Hogaboam CM. PMID: 33052708; PMCID: PMC7885832.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    13. Integrated Biomarker Discovery and Validation Implicates the Complement Pathway in Early Atherogenesis. J Am Coll Cardiol. 2020 04 28; 75(16):1942-1944. Heinecke JW, Parks WC. PMID: 32327105.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Macrophage MMP10 Regulates TLR7-Mediated Tolerance. Front Immunol. 2018; 9:2817. Rohani MG, Dimitrova E, Beppu A, Wang Y, Jefferies CA, Parks WC. PMID: 30564235; PMCID: PMC6288447.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    15. Transcriptional and functional diversity of human macrophage repolarization. J Allergy Clin Immunol. 2019 04; 143(4):1536-1548. Gharib SA, McMahan RS, Eddy WE, Long ME, Parks WC, Aitken ML, Manicone AM. PMID: 30445062; PMCID: PMC6451869.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    16. Matrix metalloproteinase-10 deficiency delays atherosclerosis progression and plaque calcification. Atherosclerosis. 2018 11; 278:124-134. Purroy A, Roncal C, Orbe J, Meilhac O, Belzunce M, Zalba G, Villa-Bellosta R, Andrés V, Parks WC, Páramo JA, Rodríguez JA. PMID: 30268068.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    17. Matrix metalloproteinases in emphysema. Matrix Biol. 2018 11; 73:34-51. Gharib SA, Manicone AM, Parks WC. PMID: 29406250; PMCID: PMC6377072.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    18. Macrophages, Wound Healing, and Fibrosis: Recent Insights. Curr Rheumatol Rep. 2018 03 17; 20(4):17. Smigiel KS, Parks WC. PMID: 29550962.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    19. Extracellular matrix in lung development, homeostasis and disease. Matrix Biol. 2018 11; 73:77-104. Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, Niklason L, Ortiz LA, Parks WC, Tschumperlin DJ, White ES, Chapman HA, Thannickal VJ. PMID: 29524630; PMCID: PMC6129220.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansCells
    20. Syndecan-1 Controls Lung Tumorigenesis by Regulating miRNAs Packaged in Exosomes. Am J Pathol. 2018 04; 188(4):1094-1103. Parimon T, Brauer R, Schlesinger SY, Xie T, Jiang D, Ge L, Huang Y, Birkland TP, Parks WC, Habiel DM, Hogaboam CM, Gharib SA, Deng N, Liu Z, Chen P. PMID: 29355516; PMCID: PMC5963476.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    21. Versican is produced by Trif- and type I interferon-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 01; 313(6):L1069-L1086. Chang MY, Kang I, Gale M, Manicone AM, Kinsella MG, Braun KR, Wigmosta T, Parks WC, Altemeier WA, Wight TN, Frevert CW. PMID: 28912382; PMCID: PMC5814701.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    22. Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury. J Immunol. 2017 06 15; 198(12):4813-4822. Eddy WE, Gong KQ, Bell B, Parks WC, Ziegler SF, Manicone AM. PMID: 28500076; PMCID: PMC5624516.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    23. Matrix Metalloproteinase-28 Is a Key Contributor to Emphysema Pathogenesis. Am J Pathol. 2017 Jun; 187(6):1288-1300. Manicone AM, Gharib SA, Gong KQ, Eddy WE, Long ME, Frevert CW, Altemeier WA, Parks WC, Houghton AM. PMID: 28399390; PMCID: PMC5455063.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCellsPHPublic Health
    24. Matrix Metalloproteinases and Leukocyte Activation. Prog Mol Biol Transl Sci. 2017; 147:167-195. Smigiel KS, Parks WC. PMID: 28413028.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    25. Lung pericyte-like cells are functional interstitial immune sentinel cells. Am J Physiol Lung Cell Mol Physiol. 2017 Apr 01; 312(4):L556-L567. Hung CF, Mittelsteadt KL, Brauer R, McKinney BL, Hallstrand TS, Parks WC, Chen P, Schnapp LM, Liles WC, Duffield JS, Altemeier WA. PMID: 28188224; PMCID: PMC5407093.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    26. Stromelysin-2 (MMP-10) facilitates clearance and moderates inflammation and cell death following lung exposure to long multiwalled carbon nanotubes. Int J Nanomedicine. 2017; 12:1019-1031. Vandivort TC, Birkland TP, Domiciano TP, Mitra S, Kavanagh TJ, Parks WC. PMID: 28223796; PMCID: PMC5304974.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    27. Filamentous Bacteriophage Produced by Pseudomonas aeruginosa Alters the Inflammatory Response and Promotes Noninvasive Infection In Vivo. Infect Immun. 2017 Jan; 85(1). Secor PR, Michaels LA, Smigiel KS, Rohani MG, Jennings LK, Hisert KB, Arrigoni A, Braun KR, Birkland TP, Lai Y, Hallstrand TS, Bollyky PL, Singh PK, Parks WC. PMID: 27795361; PMCID: PMC5203648.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    28. Interplay of extracellular matrix and leukocytes in lung inflammation. Cell Immunol. 2017 02; 312:1-14. Wight TN, Frevert CW, Debley JS, Reeves SR, Parks WC, Ziegler SF. PMID: 28077237; PMCID: PMC5290208.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    29. GM-CSF produced by the airway epithelium is required for sensitization to cockroach allergen. Mucosal Immunol. 2017 05; 10(3):705-715. Sheih A, Parks WC, Ziegler SF. PMID: 27731325; PMCID: PMC5389932.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCellsPHPublic Health
    30. Syndecan-1 Attenuates Lung Injury during Influenza Infection by Potentiating c-Met Signaling to Suppress Epithelial Apoptosis. Am J Respir Crit Care Med. 2016 08 01; 194(3):333-44. Brauer R, Ge L, Schlesinger SY, Birkland TP, Huang Y, Parimon T, Lee V, McKinney BL, McGuire JK, Parks WC, Chen P. PMID: 26959387; PMCID: PMC4970595.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    31. Shedding of Syndecan-1/CXCL1 Complexes by Matrix Metalloproteinase 7 Functions as an Epithelial Checkpoint of Neutrophil Activation. Am J Respir Cell Mol Biol. 2016 08; 55(2):243-51. Gill SE, Nadler ST, Li Q, Frevert CW, Park PW, Chen P, Parks WC. PMID: 26934670; PMCID: PMC4979362.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    32. Nonhematopoietic Peroxisome Proliferator-Activated Receptor-α Protects Against Cardiac Injury and Enhances Survival in Experimental Polymicrobial Sepsis. Crit Care Med. 2016 08; 44(8):e594-603. Standage SW, Waworuntu RL, Delaney MA, Maskal SM, Bennion BG, Duffield JS, Parks WC, Liles WC, McGuire JK. PMID: 26757163; PMCID: PMC4940302.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    33. Stromelysin-2 (MMP10) Moderates Inflammation by Controlling Macrophage Activation. J Immunol. 2016 08 01; 197(3):899-909. McMahan RS, Birkland TP, Smigiel KS, Vandivort TC, Rohani MG, Manicone AM, McGuire JK, Gharib SA, Parks WC. PMID: 27316687; PMCID: PMC4955757.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    34. Defensins Potentiate a Neutralizing Antibody Response to Enteric Viral Infection. PLoS Pathog. 2016 Mar; 12(3):e1005474. Gounder AP, Myers ND, Treuting PM, Bromme BA, Wilson SS, Wiens ME, Lu W, Ouellette AJ, Spindler KR, Parks WC, Smith JG. PMID: 26933888; PMCID: PMC4774934.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    35. An Improved Method for Rapid Intubation of the Trachea in Mice. J Vis Exp. 2016 Feb 22; (108):53771. Vandivort TC, An D, Parks WC. PMID: 26968019; PMCID: PMC4828177.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    36. CD11b(+) Mononuclear Cells Mitigate Hyperoxia-Induced Lung Injury in Neonatal Mice. Am J Respir Cell Mol Biol. 2016 Feb; 54(2):273-83. Eldredge LC, Treuting PM, Manicone AM, Ziegler SF, Parks WC, McGuire JK. PMID: 26192732; PMCID: PMC4821040.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    37. Biofilm assembly becomes crystal clear - filamentous bacteriophage organize the Pseudomonas aeruginosa biofilm matrix into a liquid crystal. Microb Cell. 2015 Dec 31; 3(1):49-52. Secor PR, Jennings LK, Michaels LA, Sweere JM, Singh PK, Parks WC, Bollyky PL. PMID: 28357315; PMCID: PMC5354590.
      View in: PubMed   Mentions: 29  
    38. Filamentous Bacteriophage Promote Biofilm Assembly and Function. Cell Host Microbe. 2015 Nov 11; 18(5):549-59. Secor PR, Sweere JM, Michaels LA, Malkovskiy AV, Lazzareschi D, Katznelson E, Rajadas J, Birnbaum ME, Arrigoni A, Braun KR, Evanko SP, Stevens DA, Kaminsky W, Singh PK, Parks WC, Bollyky PL. PMID: 26567508; PMCID: PMC4653043.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansCells
    39. Integrative pathway genomics of lung function and airflow obstruction. Hum Mol Genet. 2015 12 01; 24(23):6836-48. Gharib SA, Loth DW, Soler Artigas M, Birkland TP, Wilk JB, Wain LV, Brody JA, Obeidat M, Hancock DB, Tang W, Rawal R, Boezen HM, Imboden M, Huffman JE, Lahousse L, Alves AC, Manichaikul A, Hui J, Morrison AC, Ramasamy A, Smith AV, Gudnason V, Surakka I, Vitart V, Evans DM, Strachan DP, Deary IJ, Hofman A, Gläser S, Wilson JF, North KE, Zhao JH, Heckbert SR, Jarvis DL, Probst-Hensch N, Schulz H, Barr RG, Jarvelin MR, O'Connor GT, Kähönen M, Cassano PA, Hysi PG, Dupuis J, Hayward C, Psaty BM, Hall IP, Parks WC, Tobin MD, London SJ, CHARGE Consortium, SpiroMeta Consortium. PMID: 26395457; PMCID: PMC4643644.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    40. Correction: Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One. 2015; 10(5):e0128735. Jones HD, Yoo J, Crother TR, Kyme P, Ben-Shlomo A, Khalafi R, Tseng CW, Parks WC, Arditi M, Liu GY, Shimada K. PMID: 25996479; PMCID: PMC4440726.
      View in: PubMed   Mentions: 2     Fields:    
    41. MMP-10 Regulates Collagenolytic Activity of Alternatively Activated Resident Macrophages. J Invest Dermatol. 2015 Oct; 135(10):2377-2384. Rohani MG, McMahan RS, Razumova MV, Hertz AL, Cieslewicz M, Pun SH, Regnier M, Wang Y, Birkland TP, Parks WC. PMID: 25927164; PMCID: PMC4567949.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    42. Metalloproteinases: A parade of functions in matrix biology and an outlook for the future. Matrix Biol. 2015 May-Jul; 44-46:1-6. Apte SS, Parks WC. PMID: 25916966.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    43. Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration. PLoS One. 2015; 10(4):e0123460. Jones HD, Yoo J, Crother TR, Kyme P, Ben-Shlomo A, Khalafi R, Tseng CW, Parks WC, Arditi M, Liu GY, Shimada K. PMID: 25875775; PMCID: PMC4395431.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    44. Matrix remodeling by MMPs during wound repair. Matrix Biol. 2015 May-Jul; 44-46:113-21. Rohani MG, Parks WC. PMID: 25770908.
      View in: PubMed   Mentions: 155     Fields:    Translation:HumansAnimalsCells
    45. Mechanisms of tendon injury and repair. J Orthop Res. 2015 Jun; 33(6):832-9. Thomopoulos S, Parks WC, Rifkin DB, Derwin KA. PMID: 25641114; PMCID: PMC4418182.
      View in: PubMed   Mentions: 215     Fields:    Translation:HumansAnimals
    46. A small intestinal organoid model of non-invasive enteric pathogen-epithelial cell interactions. Mucosal Immunol. 2015 Mar; 8(2):352-61. Wilson SS, Tocchi A, Holly MK, Parks WC, Smith JG. PMID: 25118165; PMCID: PMC4326599.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    47. Amphiphilic polymer-coated CdSe/ZnS quantum dots induce pro-inflammatory cytokine expression in mouse lung epithelial cells and macrophages. Nanotoxicology. 2015 May; 9(3):336-43. Lee V, McMahan RS, Hu X, Gao X, Faustman EM, Griffith WC, Kavanagh TJ, Eaton DL, McGuire JK, Parks WC. PMID: 24983898; PMCID: PMC4669048.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    48. Systemic sensitization with the protein allergen ovalbumin augments local sensitization in atopic dermatitis. J Inflamm Res. 2014; 7:29-38. Yoo J, Manicone AM, McGuire JK, Wang Y, Parks WC. PMID: 24672255; PMCID: PMC3959805.
      View in: PubMed   Mentions: 2  
    49. Diverse functions of matrix metalloproteinases during fibrosis. Dis Model Mech. 2014 Feb; 7(2):193-203. Giannandrea M, Parks WC. PMID: 24713275; PMCID: PMC3917240.
      View in: PubMed   Mentions: 239     Fields:    Translation:HumansAnimalsCells
    50. In vitro approaches to assessing the toxicity of quantum dots. Methods Mol Biol. 2014; 1199:155-63. McMahan RS, Lee V, Parks WC, Kavanagh TJ, Eaton DL. PMID: 25103807.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    51. Matrix metalloproteinase-10 plays an active role in microvascular complications in type 1 diabetic patients. Diabetologia. 2013 Dec; 56(12):2743-52. Toni M, Hermida J, Goñi MJ, Fernández P, Parks WC, Toledo E, Montes R, Díez N. PMID: 24078057.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    52. Cdc42 inhibits ERK-mediated collagenase-1 (MMP-1) expression in collagen-activated human keratinocytes. J Invest Dermatol. 2014 May; 134(5):1230-1237. Rohani MG, Pilcher BK, Chen P, Parks WC. PMID: 24352036; PMCID: PMC3989453.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    53. Tissue inhibitor of metalloproteinases-3 moderates the proinflammatory status of macrophages. Am J Respir Cell Mol Biol. 2013 Nov; 49(5):768-77. Gill SE, Gharib SA, Bench EM, Sussman SW, Wang RT, Rims C, Birkland TP, Wang Y, Manicone AM, McGuire JK, Parks WC. PMID: 23742180; PMCID: PMC3931094.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    54. Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair. Liver Int. 2014 Aug; 34(7):e257-70. Garcia-Irigoyen O, Carotti S, Latasa MU, Uriarte I, Fernández-Barrena MG, Elizalde M, Urtasun R, Vespasiani-Gentilucci U, Morini S, Banales JM, Parks WC, Rodriguez JA, Orbe J, Prieto J, Páramo JA, Berasain C, Ávila MA. PMID: 24119197.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    55. MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis. J Leukoc Biol. 2014 Jan; 95(1):9-18. Gharib SA, Johnston LK, Huizar I, Birkland TP, Hanson J, Wang Y, Parks WC, Manicone AM. PMID: 23964118; PMCID: PMC3868192.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    56. Changes in macrophage phenotype as the immune response evolves. Curr Opin Pharmacol. 2013 Aug; 13(4):555-64. Lichtnekert J, Kawakami T, Parks WC, Duffield JS. PMID: 23747023; PMCID: PMC3732570.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    57. The glutathione synthesis gene Gclm modulates amphiphilic polymer-coated CdSe/ZnS quantum dot-induced lung inflammation in mice. PLoS One. 2013; 8(5):e64165. McConnachie LA, Botta D, White CC, Weldy CS, Wilkerson HW, Yu J, Dills R, Yu X, Griffith WC, Faustman EM, Farin FM, Gill SE, Parks WC, Hu X, Gao X, Eaton DL, Kavanagh TJ. PMID: 23724032; PMCID: PMC3664581.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    58. Macrophage migration and invasion is regulated by MMP10 expression. PLoS One. 2013; 8(5):e63555. Murray MY, Birkland TP, Howe JD, Rowan AD, Fidock M, Parks WC, Gavrilovic J. PMID: 23691065; PMCID: PMC3653827.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    59. Functional interactions between matrix metalloproteinases and glycosaminoglycans. FEBS J. 2013 May; 280(10):2332-41. Tocchi A, Parks WC. PMID: 23421805.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    60. Matrix metalloproteinase-7 coordinates airway epithelial injury response and differentiation of ciliated cells. Am J Respir Cell Mol Biol. 2013 Mar; 48(3):390-6. Gharib SA, Altemeier WA, Van Winkle LS, Plopper CG, Schlesinger SY, Buell CA, Brauer R, Lee V, Parks WC, Chen P. PMID: 23258229; PMCID: PMC3604090.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    61. Lack of MMP10 exacerbates experimental colitis and promotes development of inflammation-associated colonic dysplasia. Lab Invest. 2012 Dec; 92(12):1749-59. Koller FL, Dozier EA, Nam KT, Swee M, Birkland TP, Parks WC, Fingleton B. PMID: 23044923; PMCID: PMC3510327.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    62. Transmembrane and extracellular domains of syndecan-1 have distinct functions in regulating lung epithelial migration and adhesion. J Biol Chem. 2012 Oct 12; 287(42):34927-34935. Altemeier WA, Schlesinger SY, Buell CA, Brauer R, Rapraeger AC, Parks WC, Chen P. PMID: 22936802; PMCID: PMC3471708.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    63. Syndecan-1 controls cell migration by activating Rap1 to regulate focal adhesion disassembly. J Cell Sci. 2012 Nov 01; 125(Pt 21):5188-95. Altemeier WA, Schlesinger SY, Buell CA, Parks WC, Chen P. PMID: 22899717; PMCID: PMC3533394.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    64. Syndecan-4 regulates early neutrophil migration and pulmonary inflammation in response to lipopolysaccharide. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):196-202. Tanino Y, Chang MY, Wang X, Gill SE, Skerrett S, McGuire JK, Sato S, Nikaido T, Kojima T, Munakata M, Mongovin S, Parks WC, Martin TR, Wight TN, Frevert CW. PMID: 22427536; PMCID: PMC3423465.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    65. Matrix metalloproteinase-10 effectively reduces infarct size in experimental stroke by enhancing fibrinolysis via a thrombin-activatable fibrinolysis inhibitor-mediated mechanism. Circulation. 2011 Dec 20; 124(25):2909-19. Orbe J, Barrenetxe J, Rodriguez JA, Vivien D, Orset C, Parks WC, Birkland TP, Serrano R, Purroy A, Martinez de Lizarrondo S, Angles-Cano E, Páramo JA. PMID: 22104553.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    66. Constitutive coupling of a naturally occurring human alpha1a-adrenergic receptor genetic variant to EGFR transactivation pathway. Proc Natl Acad Sci U S A. 2011 Dec 06; 108(49):19796-801. Oganesian A, Yarov-Yarovoy V, Parks WC, Schwinn DA. PMID: 22089237; PMCID: PMC3241756.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    67. Epilysin (matrix metalloproteinase-28) contributes to airway epithelial cell survival. Respir Res. 2011 Oct 31; 12:144. Manicone AM, Harju-Baker S, Johnston LK, Chen AJ, Parks WC. PMID: 22040290; PMCID: PMC3225336.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    68. Heterozygosity in the glutathione synthesis gene Gclm increases sensitivity to diesel exhaust particulate induced lung inflammation in mice. Inhal Toxicol. 2011 Oct; 23(12):724-35. Weldy CS, White CC, Wilkerson HW, Larson TV, Stewart JA, Gill SE, Parks WC, Kavanagh TJ. PMID: 21967497; PMCID: PMC3337699.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    69. Overexpression of urokinase by plaque macrophages causes histological features of plaque rupture and increases vascular matrix metalloproteinase activity in aged apolipoprotein e-null mice. Circulation. 2010 Apr 13; 121(14):1637-44. Hu JH, Du L, Chu T, Otsuka G, Dronadula N, Jaffe M, Gill SE, Parks WC, Dichek DA. PMID: 20351234; PMCID: PMC2872172.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    70. Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs. J Immunol. 2010 Mar 01; 184(5):2677-85. Tanino Y, Coombe DR, Gill SE, Kett WC, Kajikawa O, Proudfoot AE, Wells TN, Parks WC, Wight TN, Martin TR, Frevert CW. PMID: 20124102; PMCID: PMC4113427.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    71. Mouse models of MMP and TIMP function. Methods Mol Biol. 2010; 622:31-52. Gill SE, Kassim SY, Birkland TP, Parks WC. PMID: 20135274.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    72. Role of matrix metalloproteinases in epithelial migration. J Cell Biochem. 2009 Dec 15; 108(6):1233-43. Chen P, Parks WC. PMID: 19798678; PMCID: PMC6440477.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCells
    73. Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury. Am J Pathol. 2010 Jan; 176(1):64-73. Gill SE, Huizar I, Bench EM, Sussman SW, Wang Y, Khokha R, Parks WC. PMID: 20008147; PMCID: PMC2797870.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    74. MMP7 shedding of syndecan-1 facilitates re-epithelialization by affecting alpha(2)beta(1) integrin activation. PLoS One. 2009 Aug 10; 4(8):e6565. Chen P, Abacherli LE, Nadler ST, Wang Y, Li Q, Parks WC. PMID: 19668337; PMCID: PMC2719060.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    75. Control of promatrilysin (MMP7) activation and substrate-specific activity by sulfated glycosaminoglycans. J Biol Chem. 2009 Oct 09; 284(41):27924-27932. Ra HJ, Harju-Baker S, Zhang F, Linhardt RJ, Wilson CL, Parks WC. PMID: 19654318; PMCID: PMC2788844.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    76. Cytosolic SYT/SS18 isoforms are actin-associated proteins that function in matrix-specific adhesion. PLoS One. 2009 Jul 31; 4(7):e6455. Kim J, Swee M, Parks WC. PMID: 19649286; PMCID: PMC2714072.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    77. Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines. Blood. 2009 Oct 01; 114(14):3033-43. Hayashida K, Parks WC, Park PW. PMID: 19638625; PMCID: PMC2756208.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    78. Epilysin (MMP-28) restrains early macrophage recruitment in Pseudomonas aeruginosa pneumonia. J Immunol. 2009 Mar 15; 182(6):3866-76. Manicone AM, Birkland TP, Lin M, Betsuyaku T, van Rooijen N, Lohi J, Keski-Oja J, Wang Y, Skerrett SJ, Parks WC. PMID: 19265166; PMCID: PMC2721855.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    79. Differential Processing of {alpha}- and {beta}-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7). J Biol Chem. 2009 Mar 27; 284(13):8301-11. Wilson CL, Schmidt AP, Pirilä E, Valore EV, Ferri N, Sorsa T, Ganz T, Parks WC. PMID: 19181662; PMCID: PMC2659188.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    80. MMP-9 sheds the beta2 integrin subunit (CD18) from macrophages. Mol Cell Proteomics. 2009 May; 8(5):1044-60. Vaisar T, Kassim SY, Gomez IG, Green PS, Hargarten S, Gough PJ, Parks WC, Wilson CL, Raines EW, Heinecke JW. PMID: 19116209; PMCID: PMC2689762.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    81. Tissue inhibitor of metalloproteinase-1 moderates airway re-epithelialization by regulating matrilysin activity. Am J Pathol. 2008 May; 172(5):1256-70. Chen P, McGuire JK, Hackman RC, Kim KH, Black RA, Poindexter K, Yan W, Liu P, Chen AJ, Parks WC, Madtes DK. PMID: 18385523; PMCID: PMC2329835.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    82. Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients. J Leukoc Biol. 2008 Jun; 83(6):1404-12. Swee M, Wilson CL, Wang Y, McGuire JK, Parks WC. PMID: 18334539; PMCID: PMC4139120.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    83. Erectile dysfunction in the type II diabetic db/db mouse: impaired venoocclusion with altered cavernosal vasoreactivity and matrix. Am J Physiol Heart Circ Physiol. 2008 May; 294(5):H2204-11. Luttrell IP, Swee M, Starcher B, Parks WC, Chitaley K. PMID: 18326798.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    84. Metalloproteinases and their inhibitors: regulators of wound healing. Int J Biochem Cell Biol. 2008; 40(6-7):1334-47. Gill SE, Parks WC. PMID: 18083622; PMCID: PMC2746915.
      View in: PubMed   Mentions: 250     Fields:    Translation:HumansAnimals
    85. Individual matrix metalloproteinases control distinct transcriptional responses in airway epithelial cells infected with Pseudomonas aeruginosa. Infect Immun. 2007 Dec; 75(12):5640-50. Kassim SY, Gharib SA, Mecham BH, Birkland TP, Parks WC, McGuire JK. PMID: 17923522; PMCID: PMC2168342.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    86. Matrix metalloproteinases: Introduction. Semin Cell Dev Biol. 2008 Feb; 19(1):1. Parks WC. PMID: 17662627.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    87. Control of matrix metalloproteinase catalytic activity. Matrix Biol. 2007 Oct; 26(8):587-96. Ra HJ, Parks WC. PMID: 17669641; PMCID: PMC2246078.
      View in: PubMed   Mentions: 230     Fields:    Translation:HumansAnimalsCells
    88. Activation and silencing of matrix metalloproteinases. Semin Cell Dev Biol. 2008 Feb; 19(1):2-13. Fu X, Parks WC, Heinecke JW. PMID: 17689277.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    89. What is the alpha2beta1 integrin doing in the epidermis? J Invest Dermatol. 2007 Feb; 127(2):264-6. Parks WC. PMID: 17228304.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    90. Role of airway epithelial injury in murine orthotopic tracheal allograft rejection. Ann Thorac Surg. 2006 Oct; 82(4):1226-33. Kuo E, Bharat A, Shih J, Street T, Norris J, Liu W, Parks W, Walter M, Patterson GA, Mohanakumar T. PMID: 16996912.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    91. Matrix metalloproteinases promote inflammation and fibrosis in asbestos-induced lung injury in mice. Am J Respir Cell Mol Biol. 2006 Sep; 35(3):289-97. Tan RJ, Fattman CL, Niehouse LM, Tobolewski JM, Hanford LE, Li Q, Monzon FA, Parks WC, Oury TD. PMID: 16574944; PMCID: PMC1820635.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    92. Specific sequence motifs direct the oxygenation and chlorination of tryptophan by myeloperoxidase. Biochemistry. 2006 Mar 28; 45(12):3961-71. Fu X, Wang Y, Kao J, Irwin A, d'Avignon A, Mecham RP, Parks WC, Heinecke JW. PMID: 16548523; PMCID: PMC2556706.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    93. NADPH oxidase restrains the matrix metalloproteinase activity of macrophages. J Biol Chem. 2005 Aug 26; 280(34):30201-5. Kassim SY, Fu X, Liles WC, Shapiro SD, Parks WC, Heinecke JW. PMID: 15983040.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    94. Membrane-type 1 matrix metalloproteinase is required for normal alveolar development. Dev Dyn. 2005 Apr; 232(4):1079-90. Atkinson JJ, Holmbeck K, Yamada S, Birkedal-Hansen H, Parks WC, Senior RM. PMID: 15739229.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
    95. Matrix metalloproteinase-9 modulation by resident arterial cells is responsible for injury-induced accelerated atherosclerotic plaque development in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2005 May; 25(5):1020-5. Choi ET, Collins ET, Marine LA, Uberti MG, Uchida H, Leidenfrost JE, Khan MF, Boc KP, Abendschein DR, Parks WC. PMID: 15746435.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    96. Activities of the matrix metalloproteinase stromelysin-2 (MMP-10) in matrix degradation and keratinocyte organization in wounded skin. Mol Biol Cell. 2004 Dec; 15(12):5242-54. Krampert M, Bloch W, Sasaki T, Bugnon P, Rülicke T, Wolf E, Aumailley M, Parks WC, Werner S. PMID: 15371548; PMCID: PMC532007.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    97. Implications of proprotein Convertase 5 (PC5) in the arterial restenotic process in a porcine model. Cardiovasc Pathol. 2004 Sep-Oct; 13(5):241-50. Veinot JP, Prichett-Pejic W, Picard P, Parks W, Schwartz R, Seidah NG, Chretien M. PMID: 15358338.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    98. Matrix metalloproteinases as modulators of inflammation and innate immunity. Nat Rev Immunol. 2004 Aug; 4(8):617-29. Parks WC, Wilson CL, López-Boado YS. PMID: 15286728.
      View in: PubMed   Mentions: 705     Fields:    Translation:HumansAnimalsCells
    99. Beta3-integrin mediates smooth muscle cell accumulation in neointima after carotid ligation in mice. Circulation. 2004 Mar 30; 109(12):1564-9. Choi ET, Khan MF, Leidenfrost JE, Collins ET, Boc KP, Villa BR, Novack DV, Parks WC, Abendschein DR. PMID: 15007005.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    100. Oxidative cross-linking of tryptophan to glycine restrains matrix metalloproteinase activity: specific structural motifs control protein oxidation. J Biol Chem. 2004 Feb 20; 279(8):6209-12. Fu X, Kao JL, Bergt C, Kassim SY, Huq NP, d'Avignon A, Parks WC, Mecham RP, Heinecke JW. PMID: 14670964.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    101. The mouse matrix metalloproteinase, epilysin (MMP-28), is alternatively spliced and processed by a furin-like proprotein convertase. Biochem J. 2003 Oct 01; 375(Pt 1):191-7. Illman SA, Keski-Oja J, Parks WC, Lohi J. PMID: 12803542; PMCID: PMC1223653.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    102. Matrix metalloproteinases in lung repair. Eur Respir J Suppl. 2003 Sep; 44:36s-38s. Parks WC. PMID: 14582900.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    103. A model of primary atherosclerosis and post-angioplasty restenosis in mice. Am J Pathol. 2003 Aug; 163(2):773-8. Leidenfrost JE, Khan MF, Boc KP, Villa BR, Collins ET, Parks WC, Abendschein DR, Choi ET. PMID: 12875996; PMCID: PMC1868197.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    104. Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium. Am J Pathol. 2003 Jun; 162(6):1831-43. McGuire JK, Li Q, Parks WC. PMID: 12759241; PMCID: PMC1868120.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    105. Hypochlorous acid generated by myeloperoxidase modifies adjacent tryptophan and glycine residues in the catalytic domain of matrix metalloproteinase-7 (matrilysin): an oxidative mechanism for restraining proteolytic activity during inflammation. J Biol Chem. 2003 Aug 01; 278(31):28403-9. Fu X, Kassim SY, Parks WC, Heinecke JW. PMID: 12759346.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    106. Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury. Cell. 2002 Nov 27; 111(5):635-46. Li Q, Park PW, Wilson CL, Parks WC. PMID: 12464176.
      View in: PubMed   Mentions: 340     Fields:    Translation:AnimalsCells
    107. A confederacy of proteinases. J Clin Invest. 2002 Sep; 110(5):613-4. Parks WC. PMID: 12208861; PMCID: PMC151119.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    108. Mouse strain modulates the role of the ciliated cell in acute tracheobronchial airway injury-distal airways. Am J Pathol. 2002 Jan; 160(1):315-27. Lawson GW, Van Winkle LS, Toskala E, Senior RM, Parks WC, Plopper CG. PMID: 11786425; PMCID: PMC1867146.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    109. Pathogenesis of abdominal aortic aneurysms: a multidisciplinary research program supported by the National Heart, Lung, and Blood Institute. J Vasc Surg. 2001 Oct; 34(4):730-8. Wassef M, Baxter BT, Chisholm RL, Dalman RL, Fillinger MF, Heinecke J, Humphrey JD, Kuivaniemi H, Parks WC, Pearce WH, Platsoucas CD, Sukhova GK, Thompson RW, Tilson MD, Zarins CK. PMID: 11668331.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    110. Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase. J Biol Chem. 2001 Nov 02; 276(44):41279-87. Fu X, Kassim SY, Parks WC, Heinecke JW. PMID: 11533038.
      View in: PubMed   Mentions: 154     Fields:    Translation:Cells
    111. Regulation of matrilysin expression in airway epithelial cells by Pseudomonas aeruginosa flagellin. J Biol Chem. 2001 Nov 02; 276(44):41417-23. López-Boado YS, Wilson CL, Parks WC. PMID: 11527977.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    112. Matrilysin in epithelial repair and defense. Chest. 2001 Jul; 120(1 Suppl):36S-41S. Parks WC, López-Boado YS, Wilson CL. PMID: 11451908.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    113. Pro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen. J Biol Chem. 2001 Aug 03; 276(31):29368-74. Dumin JA, Dickeson SK, Stricker TP, Bhattacharyya-Pakrasi M, Roby JD, Santoro SA, Parks WC. PMID: 11359786.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    114. Structural analysis of the alpha(2) integrin I domain/procollagenase-1 (matrix metalloproteinase-1) interaction. J Biol Chem. 2001 Aug 03; 276(31):29375-81. Stricker TP, Dumin JA, Dickeson SK, Chung L, Nagase H, Parks WC, Santoro SA. PMID: 11359774.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    115. p38 mitogen-activated kinase is a bidirectional regulator of human fibroblast collagenase-1 induction by three-dimensional collagen lattices. Biochem J. 2001 Apr 15; 355(Pt 2):437-47. Xu J, Clark RA, Parks WC. PMID: 11284732; PMCID: PMC1221756.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    116. Bromination of deoxycytidine by eosinophil peroxidase: a mechanism for mutagenesis by oxidative damage of nucleotide precursors. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1631-6. Henderson JP, Byun J, Williams MV, McCormick ML, Parks WC, Ridnour LA, Heinecke JW. PMID: 11172002; PMCID: PMC29308.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    117. Matrix metalloproteinases in lung biology. Respir Res. 2001; 2(1):10-9. Parks WC, Shapiro SD. PMID: 11686860; PMCID: PMC59564.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimals
    118. Epilysin, a novel human matrix metalloproteinase (MMP-28) expressed in testis and keratinocytes and in response to injury. J Biol Chem. 2001 Mar 30; 276(13):10134-44. Lohi J, Wilson CL, Roby JD, Parks WC. PMID: 11121398.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    119. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria. Nat Immunol. 2000 Aug; 1(2):113-8. Ayabe T, Satchell DP, Wilson CL, Parks WC, Selsted ME, Ouellette AJ. PMID: 11248802.
      View in: PubMed   Mentions: 391     Fields:    Translation:AnimalsCells
    120. Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin. Am J Pathol. 2000 Aug; 157(2):525-35. Betsuyaku T, Fukuda Y, Parks WC, Shipley JM, Senior RM. PMID: 10934155; PMCID: PMC1850142.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    121. Recent advances in molecular biological techniques and their relevance to pulmonary research. Thorax. 2000 Apr; 55(4):329-39. Robinson BW, Erle DJ, Jones DA, Shapiro S, Metzger WJ, Albelda SM, Parks WC, Boylan A. PMID: 10722774; PMCID: PMC1745722.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    122. Bacterial exposure induces and activates matrilysin in mucosal epithelial cells. J Cell Biol. 2000 Mar 20; 148(6):1305-15. López-Boado YS, Wilson CL, Hooper LV, Gordon JI, Hultgren SJ, Parks WC. PMID: 10725342; PMCID: PMC2174301.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    123. Structural analysis and promoter characterization of the human membrane-type matrix metalloproteinase-1 (MT1-MMP) gene. Gene. 2000 Jan 25; 242(1-2):75-86. Lohi J, Lehti K, Valtanen H, Parks WC, Keski-Oja J. PMID: 10721699.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    124. An open reading frame element mediates posttranscriptional regulation of tropoelastin and responsiveness to transforming growth factor beta1. Mol Cell Biol. 1999 Nov; 19(11):7314-26. Zhang M, Pierce RA, Wachi H, Mecham RP, Parks WC. PMID: 10523620; PMCID: PMC84725.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    125. Matrix metalloproteinases in repair. Wound Repair Regen. 1999 Nov-Dec; 7(6):423-32. Parks WC. PMID: 10633001.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    126. Who are the proteolytic culprits in vascular disease? J Clin Invest. 1999 Nov; 104(9):1167-8. Parks WC. PMID: 10545513; PMCID: PMC409834.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    127. Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science. 1999 Oct 01; 286(5437):113-7. Wilson CL, Ouellette AJ, Satchell DP, Ayabe T, López-Boado YS, Stratman JL, Hultgren SJ, Matrisian LM, Parks WC. PMID: 10506557.
      View in: PubMed   Mentions: 373     Fields:    Translation:HumansAnimalsCells
    128. Posttranscriptional regulation of lung elastin expression involves binding of a developmentally regulated cytosolic protein to an open-reading frame cis-element in the messenger RNA. Chest. 1999 Jul; 116(1 Suppl):74S. Zhang M, Parks WC. PMID: 10424601.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    129. Role of matrix metalloproteinases and their inhibition in cutaneous wound healing and allergic contact hypersensitivity. Ann N Y Acad Sci. 1999 Jun 30; 878:12-24. Pilcher BK, Wang M, Qin XJ, Parks WC, Senior RM, Welgus HG. PMID: 10415717.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    130. Keratinocyte collagenase-1 expression requires an epidermal growth factor receptor autocrine mechanism. J Biol Chem. 1999 Apr 09; 274(15):10372-81. Pilcher BK, Dumin J, Schwartz MJ, Mast BA, Schultz GS, Parks WC, Welgus HG. PMID: 10187826.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    131. Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli. Science. 1998 Nov 20; 282(5393):1494-7. Mulvey MA, Lopez-Boado YS, Wilson CL, Roth R, Parks WC, Heuser J, Hultgren SJ. PMID: 9822381.
      View in: PubMed   Mentions: 428     Fields:    Translation:AnimalsCells
    132. Matrilysin expression and function in airway epithelium. J Clin Invest. 1998 Oct 01; 102(7):1321-31. Dunsmore SE, Saarialho-Kere UK, Roby JD, Wilson CL, Matrisian LM, Welgus HG, Parks WC. PMID: 9769324; PMCID: PMC508979.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    133. Matrix metalloproteinases (MMPs) and their physiological inhibitors (TIMPs) are differentially expressed during excisional skin wound repair. Exp Cell Res. 1998 Jul 10; 242(1):201-10. Madlener M, Parks WC, Werner S. PMID: 9665817.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    134. Collagenase-1 and collagen in epidermal repair. Arch Dermatol Res. 1998 Jul; 290 Suppl:S37-46. Pilcher BK, Sudbeck BD, Dumin JA, Welgus HG, Parks WC. PMID: 9710382.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    135. Collagenase-1 complexes with alpha2-macroglobulin in the acute and chronic wound environments. J Invest Dermatol. 1998 May; 110(5):771-6. Grinnell F, Zhu M, Parks WC. PMID: 9579544.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    136. Induction and repression of collagenase-1 by keratinocytes is controlled by distinct components of different extracellular matrix compartments. J Biol Chem. 1997 Aug 29; 272(35):22103-10. Sudbeck BD, Pilcher BK, Welgus HG, Parks WC. PMID: 9268353.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    137. Cell type-specific inhibition of keratinocyte collagenase-1 expression by basic fibroblast growth factor and keratinocyte growth factor. A common receptor pathway. J Biol Chem. 1997 Jul 18; 272(29):18147-54. Pilcher BK, Gaither-Ganim J, Parks WC, Welgus HG. PMID: 9218449.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    138. Posttranscriptional regulation of lung elastin production. Am J Respir Cell Mol Biol. 1997 Jul; 17(1):1-2. Parks WC. PMID: 9224202.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    139. The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix. J Cell Biol. 1997 Jun 16; 137(6):1445-57. Pilcher BK, Dumin JA, Sudbeck BD, Krane SM, Welgus HG, Parks WC. PMID: 9182674; PMCID: PMC2132537.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansAnimalsCells
    140. Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta site. J Biol Chem. 1997 May 02; 272(18):11840-9. Doyle GA, Pierce RA, Parks WC. PMID: 9115242.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    141. Modulation of intracellular calcium levels inhibits secretion of collagenase 1 by migrating keratinocytes. Mol Biol Cell. 1997 May; 8(5):811-24. Sudbeck BD, Pilcher BK, Pentland AP, Parks WC. PMID: 9168468; PMCID: PMC276131.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    142. Distinct mechanisms regulate TIMP-1 expression at different stages of phorbol ester-mediated differentiation of U937 cells. Biochemistry. 1997 Mar 04; 36(9):2492-500. Doyle GA, Saarialho-Kere UK, Parks WC. PMID: 9054554.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    143. Regulation of the expression of stromelysin-2 by growth factors in keratinocytes: implications for normal and impaired wound healing. Biochem J. 1996 Dec 01; 320 ( Pt 2):659-64. Madlener M, Mauch C, Conca W, Brauchle M, Parks WC, Werner S. PMID: 8973581; PMCID: PMC1217980.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    144. Role of matrix metalloproteinases in abdominal aortic aneurysms. Ann N Y Acad Sci. 1996 Nov 18; 800:157-74. Thompson RW, Parks WC. PMID: 8958991.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    145. Collagenase-I, stromelysin-I, and matrilysin are expressed within the placenta during multiple stages of human pregnancy. Placenta. 1996 Nov; 17(8):557-63. Vettraino IM, Roby J, Tolley T, Parks WC. PMID: 8916203.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    146. Mechanisms of hepatocyte growth factor stimulation of keratinocyte metalloproteinase production. J Biol Chem. 1996 Oct 04; 271(40):24576-82. Dunsmore SE, Rubin JS, Kovacs SO, Chedid M, Parks WC, Welgus HG. PMID: 8798721.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    147. Angiotensin converting enzyme expression in primary pulmonary hypertension. Am J Respir Crit Care Med. 1996 Oct; 154(4 Pt 1):1087-91. Schuster DP, Crouch EC, Parks WC, Johnson T, Botney MD. PMID: 8887612.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    148. Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury. Am J Pathol. 1996 Oct; 149(4):1287-302. Fini ME, Parks WC, Rinehart WB, Girard MT, Matsubara M, Cook JR, West-Mays JA, Sadow PM, Burgeson RE, Jeffrey JJ, Raizman MB, Krueger RR, Zieske JD. PMID: 8863676; PMCID: PMC1865201.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    149. Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme. Proc Natl Acad Sci U S A. 1996 Sep 03; 93(18):9748-53. Halpert I, Sires UI, Roby JD, Potter-Perigo S, Wight TN, Shapiro SD, Welgus HG, Wickline SA, Parks WC. PMID: 8790402; PMCID: PMC38500.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    150. Re-epithelialization of human oral keratinocytes in vitro. J Dent Res. 1996 Mar; 75(3):912-8. Garlick JA, Parks WC, Welgus HG, Taichman LB. PMID: 8675802.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    151. Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: preservation of aortic elastin associated with suppressed production of 92 kD gelatinase. J Vasc Surg. 1996 Feb; 23(2):336-46. Petrinec D, Liao S, Holmes DR, Reilly JM, Parks WC, Thompson RW. PMID: 8637112.
      View in: PubMed   Mentions: 68     Fields:    Translation:Animals
    152. Enhanced expression of matrilysin, collagenase, and stromelysin-1 in gastrointestinal ulcers. Am J Pathol. 1996 Feb; 148(2):519-26. Saarialho-Kere UK, Vaalamo M, Puolakkainen P, Airola K, Parks WC, Karjalainen-Lindsberg ML. PMID: 8579114; PMCID: PMC1861683.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    153. Localization of type I procollagen gene expression in silica-induced granulomatous lung disease and implication of transforming growth factor-beta as a mediator of fibrosis. Am J Pathol. 1996 Jan; 148(1):151-64. Mariani TJ, Roby JD, Mecham RP, Parks WC, Crouch E, Pierce RA. PMID: 8546202; PMCID: PMC1861615.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    154. In situ hybridization of human erythropoietin in pre- and postnatal kidneys. Pediatr Pathol Lab Med. 1995 Nov-Dec; 15(6):875-83. Liapis H, Roby J, Birkland TP, Davila RM, Ritter D, Parks WC. PMID: 8705198.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    155. Osteopontin expression is increased in the heritable cardiomyopathy of Syrian hamsters. Circulation. 1995 Aug 15; 92(4):705-9. Williams EB, Halpert I, Wickline S, Davison G, Parks WC, Rottman JN. PMID: 7641347.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    156. Human dermal microvascular endothelial cells produce matrix metalloproteinases in response to angiogenic factors and migration. J Invest Dermatol. 1995 Aug; 105(2):170-6. Cornelius LA, Nehring LC, Roby JD, Parks WC, Welgus HG. PMID: 7543547.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    157. Matrix metalloproteinase matrilysin is constitutively expressed in adult human exocrine epithelium. J Invest Dermatol. 1995 Aug; 105(2):190-6. Saarialho-Kere UK, Crouch EC, Parks WC. PMID: 7636300.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    158. Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages. J Clin Invest. 1995 Jul; 96(1):318-26. Thompson RW, Holmes DR, Mertens RA, Liao S, Botney MD, Mecham RP, Welgus HG, Parks WC. PMID: 7615801; PMCID: PMC185203.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansCells
    159. Developmental regulation of elastin production. Expression of tropoelastin pre-mRNA persists after down-regulation of steady-state mRNA levels. J Biol Chem. 1995 Jun 23; 270(25):14899-906. Swee MH, Parks WC, Pierce RA. PMID: 7797468.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    160. Matrilysin expression by human mononuclear phagocytes and its regulation by cytokines and hormones. J Immunol. 1995 Jun 15; 154(12):6484-91. Busiek DF, Baragi V, Nehring LC, Parks WC, Welgus HG. PMID: 7759883.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    161. Interstitial collagenase is expressed by keratinocytes that are actively involved in reepithelialization in blistering skin disease. J Invest Dermatol. 1995 Jun; 104(6):982-8. Saarialho-Kere UK, Vaalamo M, Airola K, Niemi KM, Oikarinen AI, Parks WC. PMID: 7539470.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    162. Medial neovascularization in abdominal aortic aneurysms: a histopathologic marker of aneurysmal degeneration with pathophysiologic implications. J Vasc Surg. 1995 May; 21(5):761-71; discussion 771-2. Holmes DR, Liao S, Parks WC, Thompson RW. PMID: 7539511.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    163. Glucocorticoids upregulate tropoelastin expression during late stages of fetal lung development. Am J Physiol. 1995 Mar; 268(3 Pt 1):L491-500. Pierce RA, Mariencheck WI, Sandefur S, Crouch EC, Parks WC. PMID: 7900831.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    164. Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung. J Immunol. 1995 Feb 15; 154(4):1861-9. Haviland DL, McCoy RL, Whitehead WT, Akama H, Molmenti EP, Brown A, Haviland JC, Parks WC, Perlmutter DH, Wetsel RA. PMID: 7836770.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    165. Fibrillin-1 and fibrillin-2 show temporal and tissue-specific regulation of expression in developing elastic tissues. Connect Tissue Res. 1995; 31(2):87-97. Mariencheck MC, Davis EC, Zhang H, Ramirez F, Rosenbloom J, Gibson MA, Parks WC, Mecham RP. PMID: 15612324.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    166. Persistence, re-expression, and induction of pulmonary arterial fibronectin, tropoelastin, and type I procollagen mRNA expression in neonatal hypoxic pulmonary hypertension. Am J Pathol. 1994 Dec; 145(6):1411-20. Durmowicz AG, Parks WC, Hyde DM, Mecham RP, Stenmark KR. PMID: 7992844; PMCID: PMC1887497.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    167. Collagen-stimulated induction of keratinocyte collagenase is mediated via tyrosine kinase and protein kinase C activities. J Biol Chem. 1994 Nov 25; 269(47):30022-9. Sudbeck BD, Parks WC, Welgus HG, Pentland AP. PMID: 7962003.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    168. Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part IV: Effects on expression of extracellular matrix genes. Res Rep Health Eff Inst. 1994 Oct; (65 Pt 4):3-20; discussion 21-9. Parks WC, Roby JD. PMID: 7840908.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    169. Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds. J Clin Invest. 1994 Jul; 94(1):79-88. Saarialho-Kere UK, Pentland AP, Birkedal-Hansen H, Parks WC, Welgus HG. PMID: 8040294; PMCID: PMC296284.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    170. The regulation of collagen in fetal skin wounds: mRNA localization and analysis. J Pediatr Surg. 1994 Jul; 29(7):855-62. Nath RK, Parks WC, Mackinnon SE, Hunter DA, Markham H, Weeks PM. PMID: 7931957.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    171. Conversion to an elastogenic phenotype by fetal hyaline chondrocytes is accompanied by altered expression of elastin-related macromolecules. Dev Biol. 1994 May; 163(1):241-52. Lee KA, Pierce RA, Davis EC, Mecham RP, Parks WC. PMID: 8174780.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    172. 92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen. J Clin Invest. 1994 May; 93(5):2022-30. Ståhle-Bäckdahl M, Inoue M, Guidice GJ, Parks WC. PMID: 8182134; PMCID: PMC294314.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    173. Increased mesenchymal cell density accompanies induction of tropoelastin expression in developing elastic tissue. Dev Dyn. 1994 May; 200(1):53-67. Lee KA, Pierce RA, Mecham RP, Parks WC. PMID: 8081014.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    174. Uncoordinate regulation of collagenase, stromelysin, and tissue inhibitor of metalloproteinases genes by prostaglandin E2: selective enhancement of collagenase gene expression in human dermal fibroblasts in culture. J Cell Biochem. 1994 Apr; 54(4):465-72. Mauviel A, Halcin C, Vasiloudes P, Parks WC, Kurkinen M, Uitto J. PMID: 8014195.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    175. Persistence of the fetal pattern of tropoelastin gene expression in severe neonatal bovine pulmonary hypertension. J Clin Invest. 1994 Mar; 93(3):1234-42. Stenmark KR, Durmowicz AG, Roby JD, Mecham RP, Parks WC. PMID: 8132763; PMCID: PMC294075.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    176. Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing. J Clin Invest. 1993 Dec; 92(6):2858-66. Saarialho-Kere UK, Kovacs SO, Pentland AP, Olerud JE, Welgus HG, Parks WC. PMID: 8254040; PMCID: PMC288487.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    177. Effects of 20 months of ozone exposure on lung collagen in Fischer 344 rats. Toxicology. 1993 Nov 12; 84(1-3):83-102. Last JA, Gelzleichter T, Harkema J, Parks WC, Mellick P. PMID: 8266340.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    178. Distinct mechanisms regulate interstitial collagenase and 92-kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin. J Biol Chem. 1993 Aug 15; 268(23):17354-61. Saarialho-Kere UK, Welgus HG, Parks WC. PMID: 8394340.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    179. Active collagen synthesis by pulmonary arteries in human primary pulmonary hypertension. Am J Pathol. 1993 Jul; 143(1):121-9. Botney MD, Liptay MJ, Kaiser LR, Cooper JD, Parks WC, Mecham RP. PMID: 7686340; PMCID: PMC1886956.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    180. Molecular mechanisms regulating the production of collagenase and TIMP in U937 cells: evidence for involvement of delayed transcriptional activation and enhanced mRNA stability. Biochemistry. 1993 Apr 27; 32(16):4286-92. Shapiro SD, Doyle GA, Ley TJ, Parks WC, Welgus HG. PMID: 8476858.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    181. 92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma. Am J Pathol. 1993 Apr; 142(4):995-1000. Ståhle-Bäckdahl M, Parks WC. PMID: 7682768; PMCID: PMC1886874.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    182. Expression of interstitial collagenase, 92-kDa gelatinase, and tissue inhibitor of metalloproteinases-1 in granuloma annulare and necrobiosis lipoidica diabeticorum. J Invest Dermatol. 1993 Mar; 100(3):335-42. Saarialho-Kere UK, Chang ES, Welgus HG, Parks WC. PMID: 8382717.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    183. Neointimal macrophages colocalize with extracellular matrix gene expression in human atherosclerotic pulmonary arteries. J Clin Invest. 1993 Feb; 91(2):588-94. Liptay MJ, Parks WC, Mecham RP, Roby J, Kaiser LR, Cooper JD, Botney MD. PMID: 8432864; PMCID: PMC287987.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    184. Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma. J Clin Invest. 1992 Nov; 90(5):1952-7. Saarialho-Kere UK, Chang ES, Welgus HG, Parks WC. PMID: 1430217; PMCID: PMC443257.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    185. Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma. J Invest Dermatol. 1992 Oct; 99(4):497-503. Ståhle-Bäckdahl M, Sudbeck BD, Eisen AZ, Welgus HG, Parks WC. PMID: 1402008.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    186. Phorbol ester-mediated downregulation of tropoelastin expression is controlled by a posttranscriptional mechanism. Biochemistry. 1992 Jul 28; 31(29):6639-45. Parks WC, Kolodziej ME, Pierce RA. PMID: 1637804.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    187. 1,25-Dihydroxyvitamin D3 represses tropoelastin expression by a posttranscriptional mechanism. J Biol Chem. 1992 Jun 05; 267(16):11593-9. Pierce RA, Kolodziej ME, Parks WC. PMID: 1597486.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    188. Transforming growth factor-beta 1 is decreased in remodeling hypertensive bovine pulmonary arteries. J Clin Invest. 1992 May; 89(5):1629-35. Botney MD, Parks WC, Crouch EC, Stenmark K, Mecham RP. PMID: 1569202; PMCID: PMC443039.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    189. Cellular expression of tropoelastin mRNA splice variants. Matrix. 1992 Apr; 12(2):156-62. Parks WC, Roby JD, Wu LC, Grosso LE. PMID: 1603038.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    190. Purification and characterization of bovine interstitial collagenase and tissue inhibitor of metalloproteinases. Arch Biochem Biophys. 1992 Mar; 293(2):370-6. Sudbeck BD, Jeffrey JJ, Welgus HG, Mecham RP, McCourt D, Parks WC. PMID: 1311165.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    191. Extracellular matrix protein gene expression in atherosclerotic hypertensive pulmonary arteries. Am J Pathol. 1992 Feb; 140(2):357-64. Botney MD, Kaiser LR, Cooper JD, Mecham RP, Parghi D, Roby J, Parks WC. PMID: 1739129; PMCID: PMC1886436.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    192. Neutral proteinase expression by human mononuclear phagocytes: a prominent role of cellular differentiation. Matrix Suppl. 1992; 1:363-7. Welgus HG, Senior RM, Parks WC, Kahn AJ, Ley TJ, Shapiro SD, Campbell EJ. PMID: 1480061.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    193. Binding of elastin to Staphylococcus aureus. J Biol Chem. 1991 Dec 05; 266(34):23399-406. Park PW, Roberts DD, Grosso LE, Parks WC, Rosenbloom J, Abrams WR, Mecham RP. PMID: 1744133.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    194. Hypoxia-induced inhibition of tropoelastin synthesis by neonatal calf pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol. 1991 Nov; 5(5):464-9. Durmowicz AG, Badesch DB, Parks WC, Mecham RP, Stenmark KR. PMID: 1718337.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    195. Cellular adaptation during chronic neonatal hypoxic pulmonary hypertension. Am J Physiol. 1991 10; 261(4 Suppl):97-104. Stenmark KR, Aldashev AA, Orton EC, Durmowicz AG, Badesch DB, Parks WC, Mecham RP, Voelkel NF, Reeves JT. PMID: 1928459.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    196. Connective tissue production by vascular smooth muscle in development and disease. Chest. 1991 Mar; 99(3 Suppl):43S-47S. Mecham RP, Stenmark KR, Parks WC. PMID: 1997269.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    197. Determination of transforming growth factor-beta mRNA levels in pulmonary arteries from normal and hypoxic calves. Chest. 1991 Mar; 99(3 Suppl):42S. Botney M, Parks W, Stenmark K, Mecham R. PMID: 1997268.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    198. Fibroblast adhesion to recombinant tropoelastin expressed as a protein A-fusion protein. Biochem J. 1991 Feb 01; 273 ( Pt 3):517-22. Grosso LE, Parks WC, Wu LJ, Mecham RP. PMID: 1996952; PMCID: PMC1149793.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    199. PDGF A-chain gene is expressed by mammalian neurons during development and in maturity. Cell. 1991 Jan 11; 64(1):209-16. Yeh HJ, Ruit KG, Wang YX, Parks WC, Snider WD, Deuel TF. PMID: 1986867.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    200. Inhibition of tropoelastin expression by 1,25-dihydroxyvitamin D3. Connect Tissue Res. 1991; 26(3):155-66. Hinek A, Botney MD, Mecham RP, Parks WC. PMID: 1769236.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    201. Polyclonal antibodies to tropoelastin and the specific detection and measurement of tropoelastin in vitro. Connect Tissue Res. 1991; 25(3-4):265-79. Prosser IW, Whitehouse LA, Parks WC, Stahle-Bäckdahl M, Hinek A, Park PW, Mecham RP. PMID: 2060302.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    202. Tropoelastin heterogeneity: implications for protein function and disease. Am J Respir Cell Mol Biol. 1990 May; 2(5):399-406. Parks WC, Deak SB. PMID: 2187489.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    203. Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization. Am J Pathol. 1989 Dec; 135(6):1073-88. Prosser IW, Stenmark KR, Suthar M, Crouch EC, Mecham RP, Parks WC. PMID: 2596571; PMCID: PMC1880484.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    204. Serological confirmation of human T-lymphotropic virus type I infection in healthy blood and plasma donors. Blood. 1989 Nov 15; 74(7):2585-91. Anderson DW, Epstein JS, Lee TH, Lairmore MD, Saxinger C, Kalyanaraman VS, Slamon D, Parks W, Poiesz BJ, Pierik LT, et al. PMID: 2804381.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    205. Response of lobar vessels to hypoxic pulmonary hypertension. Am Rev Respir Dis. 1989 Nov; 140(5):1455-7. Parks WC, Mecham RP, Crouch EC, Orton EC, Stenmark KR. PMID: 2817612.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    206. Regulation of collagen production by medial smooth muscle cells in hypoxic pulmonary hypertension. Am Rev Respir Dis. 1989 Oct; 140(4):1045-51. Crouch EC, Parks WC, Rosenbaum JL, Chang D, Whitehouse L, Wu LJ, Stenmark KR, Orton EC, Mecham RP. PMID: 2478055.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    207. Smooth muscle isoactin and elastin in fetal bovine lung. Exp Lung Res. 1989 Jul; 15(4):537-52. Noguchi A, Reddy R, Kursar JD, Parks WC, Mecham RP. PMID: 2767003.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    208. Insulin-like growth factor I stimulates elastin synthesis by bovine pulmonary arterial smooth muscle cells. Biochem Biophys Res Commun. 1989 Apr 14; 160(1):382-7. Badesch DB, Lee PD, Parks WC, Stenmark KR. PMID: 2653320.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    209. Structure of the bovine elastin gene and S1 nuclease analysis of alternative splicing of elastin mRNA in the bovine nuchal ligament. Biochemistry. 1989 Mar 21; 28(6):2365-70. Yeh H, Anderson N, Ornstein-Goldstein N, Bashir MM, Rosenbloom JC, Abrams W, Indik Z, Yoon K, Parks W, Mecham R, et al. PMID: 2543440.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    210. Terminal differentiation of nuchal ligament fibroblasts: characterization of synthetic properties and responsiveness to external stimuli. Dev Biol. 1988 Oct; 129(2):555-64. Parks WC, Whitehouse LA, Wu LC, Mecham RP. PMID: 3417052.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    211. Developmental regulation of tropoelastin isoforms. J Biol Chem. 1988 Mar 25; 263(9):4416-23. Parks WC, Secrist H, Wu LC, Mecham RP. PMID: 3346253.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    212. Vascular remodeling in neonatal pulmonary hypertension. Role of the smooth muscle cell. Chest. 1988 Mar; 93(3 Suppl):127S-133S. Stenmark KR, Orton EC, Reeves JT, Voelkel NF, Crouch EC, Parks WC, Mecham RP. PMID: 3342691.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    213. Smooth muscle-mediated connective tissue remodeling in pulmonary hypertension. Science. 1987 Jul 24; 237(4813):423-6. Mecham RP, Whitehouse LA, Wrenn DS, Parks WC, Griffin GL, Senior RM, Crouch EC, Stenmark KR, Voelkel NF. PMID: 3603030.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    214. Identification of multiple tropoelastins secreted by bovine cells. J Biol Chem. 1987 Feb 15; 262(5):2244-9. Wrenn DS, Parks WC, Whitehouse LA, Crouch EC, Kucich U, Rosenbloom J, Mecham RP. PMID: 2434478.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    215. Fibroblasts from patients with inherited predisposition to retinoblastoma exhibit normal sensitivity to the mutagenic effects of ionizing radiation. Mutat Res. 1986 Oct; 175(2):107-14. Wang Y, Parks WC, Wigle JC, Maher VM, McCormick JJ. PMID: 3762576.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    216. Insulin mediates the stimulation of pyruvate kinase by a dual mechanism. Biochem J. 1982 Nov 15; 208(2):333-7. Parks WC, Drake RL. PMID: 6760859; PMCID: PMC1153968.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    217. Specificity and age of appearance of natural immunity to MTV antigens. Proc Soc Exp Biol Med. 1978 May; 158(1):23-7. Lopez DM, Sigel MM, Ortiz-Muniz G, Parks W. PMID: 78494.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
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