Loading...

David S Williams

Title(s)Professor-in-Residence, Ophthalmology
SchoolMedicine
Phone59546
vCardDownload vCard
    Other Positions
    Title(s)Professor-in-Residence, Neurobiology


    Collapse Research 
    Collapse Research Activities and Funding
    Exploring the relationship of water flow across the RPE and mutant-MYO7A/Usher 1B
    NIH/NEI R21EY031109Jan 1, 2020 - Dec 31, 2021
    Role: Principal Investigator
    FASEB SRC on The Biology and Chemistry of Vision
    NIH/NEI R13EY030354Jun 1, 2019 - May 31, 2020
    Role: Principal Investigator
    RPE cell biology, aging, and disease
    NIH/NEI R01EY027442Sep 1, 2017 - May 31, 2022
    Role: Principal Investigator
    Photoreceptor disk membrane morphogenesis
    NIH/NEI R01EY024667Apr 1, 2015 - Mar 31, 2019
    Role: Co-Principal Investigator
    The Photoreceptor Cilium
    NIH/NEI R01EY013408Sep 30, 2001 - Sep 29, 2012
    Role: Principal Investigator
    Stein Eye Institute Core Grant for Vision Research
    NIH/NEI P30EY000331Mar 1, 1997 - Nov 30, 1988
    Role: Principal Investigator
    TRANSMISSION ELECTRON MICROSCOPE
    NIH/NCRR S10RR008337May 16, 1994 - May 15, 1995
    Role: Principal Investigator
    RPE Cell Biology of Myosin VIIa
    NIH/NEI R01EY007042Sep 30, 1986 - Nov 30, 2008
    Role: Principal Investigator
    IN VITRO STUDIES OF CELLULAR PROCESSES IN RODS AND CONES
    NIH/NEI R01EY005410Sep 30, 1985 - Sep 29, 1986
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Pijpers IAB, Cao S, Llopis-Lorente A, Zhu J, Song S, Joosten RRM, Meng F, Friedrich H, Williams DS, Sánchez S, van Hest JCM, Abdelmohsen LKEA. Hybrid Biodegradable Nanomotors through Compartmentalized Synthesis. Nano Lett. 2020 May 22. PMID: 32427492.
      View in: PubMed
    2. Ridolfo R, Arends JJ, van Hest JCM, Williams DS. Worm-like nanovector with enhanced drug loading using blends of biodegradable block copolymers. Biomacromolecules. 2020 Mar 25. PMID: 32208660.
      View in: PubMed
    3. Lakkaraju A, Umapathy A, Tan LX, Daniele L, Philp NJ, Boesze-Battaglia K, Williams DS. The cell biology of the retinal pigment epithelium. Prog Retin Eye Res. 2020 Feb 24; 100846. PMID: 32105772.
      View in: PubMed
    4. Williams DS, Mouradov D, Newman MR, Amini E, Nickless DK, Fang CG, Palmieri M, Sakthianandeswaren A, Li S, Ward RL, Hawkins NJ, Skinner I, Jones I, Gibbs P, Sieber OM. Tumour infiltrating lymphocyte status is superior to histological grade, DNA mismatch repair and BRAF mutation for prognosis of colorectal adenocarcinomas with mucinous differentiation. Mod Pathol. 2020 Feb 11. PMID: 32047231.
      View in: PubMed
    5. Milstein ML, Cavanaugh BL, Roussey NM, Volland S, Williams DS, Goldberg AFX. Multistep peripherin-2/rds self-assembly drives membrane curvature for outer segment disk architecture and photoreceptor viability. Proc Natl Acad Sci U S A. 2020 Feb 25; 117(8):4400-4410. PMID: 32041874.
      View in: PubMed
    6. Williams DS. Hepatic Adenoma. J Insur Med. 2020 Feb 05. PMID: 32023148.
      View in: PubMed
    7. Dávalos-Salas M, Montgomery MK, Reehorst CM, Nightingale R, Ng I, Anderton H, Al-Obaidi S, Lesmana A, Scott CM, Ioannidis P, Kalra H, Keerthikumar S, Tögel L, Rigopoulos A, Gong SJ, Williams DS, Yoganantharaja P, Bell-Anderson K, Mathivanan S, Gibert Y, Hiebert S, Scott AM, Watt MJ, Mariadason JM. Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity. Nat Commun. 2019 11 22; 10(1):5291. PMID: 31757939.
      View in: PubMed
    8. Lau DK, Mouradov D, Wasenang W, Luk IY, Scott CM, Williams DS, Yeung YH, Limpaiboon T, Iatropoulos GF, Jenkins LJ, Reehorst CM, Chionh F, Nikfarjam M, Croagh D, Dhillon AS, Weickhardt AJ, Muramatsu T, Saito Y, Tebbutt NC, Sieber OM, Mariadason JM. Genomic Profiling of Biliary Tract Cancer Cell Lines Reveals Molecular Subtypes and Actionable Drug Targets. iScience. 2019 Nov 22; 21:624-637. PMID: 31731200.
      View in: PubMed
    9. Daniele LL, Caughey J, Volland S, Sharp RC, Dhingra A, Williams DS, Philp NJ, Boesze-Battaglia K. Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B). Am J Physiol Cell Physiol. 2019 Dec 01; 317(6):C1194-C1204. PMID: 31577510.
      View in: PubMed
    10. Loh Z, Williams DS, Salmon L, Dow E, John T. Impact of universal immunohistochemistry on Lynch syndrome diagnosis in an Australian colorectal cancer cohort. Intern Med J. 2019 10; 49(10):1278-1284. PMID: 30667141.
      View in: PubMed
    11. Heuzé ML, Sankara Narayana GHN, D'Alessandro J, Cellerin V, Dang T, Williams DS, Van Hest JC, Marcq P, Mège RM, Ladoux B. Myosin II isoforms play distinct roles in adherens junction biogenesis. Elife. 2019 09 05; 8. PMID: 31486768.
      View in: PubMed
    12. Williams DS, Mouradov D, Browne C, Palmieri M, Elliott MJ, Nightingale R, Fang CG, Li R, Mariadason JM, Faragher I, Jones IT, Churilov L, Tebbutt NC, Gibbs P, Sieber OM. Overexpression of TP53 protein is associated with the lack of adjuvant chemotherapy benefit in patients with stage III colorectal cancer. Mod Pathol. 2020 Mar; 33(3):483-495. PMID: 31471586.
      View in: PubMed
    13. Cao S, Shao J, Xia Y, Che H, Zhong Z, Meng F, van Hest JCM, Abdelmohsen LKEA, Williams DS. Molecular Programming of Biodegradable Nanoworms via Ionically Induced Morphology Switch toward Asymmetric Therapeutic Carriers. Small. 2019 Sep; 15(38):e1901849. PMID: 31379132.
      View in: PubMed
    14. Li J, Liu X, Abdelmohsen LKEA, Williams DS, Huang X. Spatial Organization in Proteinaceous Membrane-Stabilized Coacervate Protocells. Small. 2019 Sep; 15(36):e1902893. PMID: 31298806.
      View in: PubMed
    15. Mason AF, Yewdall NA, Welzen PLW, Shao J, van Stevendaal M, van Hest JCM, Williams DS, Abdelmohsen LKEA. Mimicking Cellular Compartmentalization in a Hierarchical Protocell through Spontaneous Spatial Organization. ACS Cent Sci. 2019 Aug 28; 5(8):1360-1365. PMID: 31482118.
      View in: PubMed
    16. Varlas S, Foster JC, Georgiou PG, Keogh R, Husband JT, Williams DS, O'Reilly RK. Tuning the membrane permeability of polymersome nanoreactors developed by aqueous emulsion polymerization-induced self-assembly. Nanoscale. 2019 Jul 14; 11(26):12643-12654. PMID: 31237603.
      View in: PubMed
    17. Williams DS. Behcet's Disease. J Insur Med. 2019; 48(1):103-105. PMID: 31194600.
      View in: PubMed
    18. Chadha A, Volland S, Baliaouri NV, Tran EM, Williams DS. The route of the visual receptor rhodopsin along the cilium. J Cell Sci. 2019 May 15; 132(10). PMID: 30975916.
      View in: PubMed
    19. Hall V, Trubiano JA, Kwong JC, Williams DS, Holmes NE. Immunosuppressed Returned Traveler With Ulcerating Skin Lesion and Fever. Clin Infect Dis. 2019 05 02; 68(10):1747-1749. PMID: 31506697.
      View in: PubMed
    20. Williams DS. Abnormal Head CT Imaging in Afghanistan: Empiric Treatment of Abnormal Findings in an Austere Environment. J Insur Med. 2018; 47(4):265-268. PMID: 30848996.
      View in: PubMed
    21. Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. Correction to: Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2019 Feb 12; 10(1):52. PMID: 30755264.
      View in: PubMed
    22. Shao J, Pijpers IAB, Cao S, Williams DS, Yan X, Li J, Abdelmohsen LKEA, van Hest JCM. Biomorphic Engineering of Multifunctional Polylactide Stomatocytes toward Therapeutic Nano-Red Blood Cells. Adv Sci (Weinh). 2019 Mar 06; 6(5):1801678. PMID: 30886797.
      View in: PubMed
    23. Umapathy A, Williams DS. Live Imaging of Organelle Motility in RPE Flatmounts. Adv Exp Med Biol. 2019; 1185:389-393. PMID: 31884643.
      View in: PubMed
    24. Loh Z, Yeo B, Williams DS, Gyorki DE. Ectopic breast cancer in the inguinal region. Breast J. 2019 01; 25(1):155-156. PMID: 30592120.
      View in: PubMed
    25. Cao S, Abdelmohsen LKEA, Shao J, van den Dikkenberg J, Mastrobattista E, Williams DS, van Hest JCM. pH-Induced Transformation of Biodegradable Multilamellar Nanovectors for Enhanced Tumor Penetration. ACS Macro Lett. 2018 Nov 20; 7(11):1394-1399. PMID: 30533279.
      View in: PubMed
    26. Hazim RA, Volland S, Yen A, Burgess BL, Williams DS. Rapid differentiation of the human RPE cell line, ARPE-19, induced by nicotinamide. Exp Eye Res. 2019 02; 179:18-24. PMID: 30336127.
      View in: PubMed
    27. Wauters AC, Pijpers IAB, Mason AF, Williams DS, Tel J, Abdelmohsen LKEA, van Hest JCM. Development of Morphologically Discrete PEG-PDLLA Nanotubes for Precision Nanomedicine. Biomacromolecules. 2019 01 14; 20(1):177-183. PMID: 30265794.
      View in: PubMed
    28. Wallace H, Williams DS, Pefanis A. A Fad Diet Causing Acute Kidney Injury. Nephrology (Carlton). 2018 10; 23(10):962-963. PMID: 30251315.
      View in: PubMed
    29. De Jong E, Williams DS, Abdelmohsen LKEA, Van Hest JCM, Zuhorn IS. A filter-free blood-brain barrier model to quantitatively study transendothelial delivery of nanoparticles by fluorescence spectroscopy. J Control Release. 2018 11 10; 289:14-22. PMID: 30243824.
      View in: PubMed
    30. Arulananda S, Thapa B, Walkiewicz M, Zapparoli GV, Williams DS, Dobrovic A, John T. Mismatch Repair Protein Defects and Microsatellite Instability in Malignant Pleural Mesothelioma. J Thorac Oncol. 2018 10; 13(10):1588-1594. PMID: 30056163.
      View in: PubMed
    31. Ridolfo R, Ede BC, Diamanti P, White PB, Perriman AW, van Hest JCM, Blair A, Williams DS. Biodegradable, Drug-Loaded Nanovectors via Direct Hydration as a New Platform for Cancer Therapeutics. Small. 2018 08; 14(32):e1703774. PMID: 29999236.
      View in: PubMed
    32. Shao J, Abdelghani M, Shen G, Cao S, Williams DS, van Hest JCM. Erythrocyte Membrane Modified Janus Polymeric Motors for Thrombus Therapy. ACS Nano. 2018 05 22; 12(5):4877-4885. PMID: 29733578.
      View in: PubMed
    33. Esteve-Rudd J, Hazim RA, Diemer T, Paniagua AE, Volland S, Umapathy A, Williams DS. Defective phagosome motility and degradation in cell nonautonomous RPE pathogenesis of a dominant macular degeneration. Proc Natl Acad Sci U S A. 2018 05 22; 115(21):5468-5473. PMID: 29735674.
      View in: PubMed
    34. Williams DS, Mouradov D, Jorissen RN, Newman MR, Amini E, Nickless DK, Teague JA, Fang CG, Palmieri M, Parsons MJ, Sakthianandeswaren A, Li S, Ward RL, Hawkins NJ, Faragher I, Jones IT, Gibbs P, Sieber OM. Lymphocytic response to tumour and deficient DNA mismatch repair identify subtypes of stage II/III colorectal cancer associated with patient outcomes. Gut. 2018 Jan 30. PMID: 29382774.
      View in: PubMed
    35. Hazim RA, Williams DS. Cell Culture Analysis of the Phagocytosis of Photoreceptor Outer Segments by Primary Mouse RPE Cells. Methods Mol Biol. 2018; 1753:63-71. PMID: 29564781.
      View in: PubMed
    36. Volland S, Williams DS. Preservation of Photoreceptor Nanostructure for Electron Tomography Using Transcardiac Perfusion Followed by High-Pressure Freezing and Freeze-Substitution. Adv Exp Med Biol. 2018; 1074:603-607. PMID: 29721993.
      View in: PubMed
    37. Williams DS. Neck Mass in a Five-year-old Afghan Child. J Insur Med. 2018 Jan; 47(3):191-193. PMID: 30192721.
      View in: PubMed
    38. Mason AF, Buddingh' BC, Williams DS, van Hest JCM. Hierarchical Self-Assembly of a Copolymer-Stabilized Coacervate Protocell. J Am Chem Soc. 2017 12 06; 139(48):17309-17312. PMID: 29134798.
      View in: PubMed
    39. Pijpers IAB, Abdelmohsen LKEA, Williams DS, van Hest JCM. Morphology Under Control: Engineering Biodegradable Stomatocytes. ACS Macro Lett. 2017 Nov 21; 6(11):1217-1222. PMID: 29214115.
      View in: PubMed
    40. Hazim RA, Karumbayaram S, Jiang M, Dimashkie A, Lopes VS, Li D, Burgess BL, Vijayaraj P, Alva-Ornelas JA, Zack JA, Kohn DB, Gomperts BN, Pyle AD, Lowry WE, Williams DS. Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2017 10 02; 8(1):217. PMID: 28969679.
      View in: PubMed
    41. Galloway CA, Dalvi S, Hung SSC, MacDonald LA, Latchney LR, Wong RCB, Guymer RH, Mackey DA, Williams DS, Chung MM, Gamm DM, Pébay A, Hewitt AW, Singh R. Drusen in patient-derived hiPSC-RPE models of macular dystrophies. Proc Natl Acad Sci U S A. 2017 09 26; 114(39):E8214-E8223. PMID: 28878022.
      View in: PubMed
    42. Jing N, Fang C, Williams DS. Validity and reliability of Ki-67 assessment in oestrogen receptor positive breast cancer. Pathology. 2017 Jun; 49(4):371-378. PMID: 28450087.
      View in: PubMed
    43. Williams DS, Pijpers IAB, Ridolfo R, van Hest JCM. Controlling the morphology of copolymeric vectors for next generation nanomedicine. J Control Release. 2017 08 10; 259:29-39. PMID: 28257992.
      View in: PubMed
    44. Williams DS. Mesenteric Panniculitis. J Insur Med. 2017; 47(2):130-132. PMID: 29490158.
      View in: PubMed
    45. Williams DS. Kikuchi Disease. J Insur Med. 2017; 47(1):55-57. PMID: 28836904.
      View in: PubMed
    46. Lau LF, Murone C, Williams DS, Standish R, Lee ST, Christophi C, Scott AM, Muralidharan V. Metabolic response evaluation for colorectal liver metastases and correlation to pathologic response and tumour markers. ANZ J Surg. 2018 Mar; 88(3):E108-E113. PMID: 27452367.
      View in: PubMed
    47. Abdelmohsen LK, Williams DS, Pille J, Ozel SG, Rikken RS, Wilson DA, van Hest JC. Formation of Well-Defined, Functional Nanotubes via Osmotically Induced Shape Transformation of Biodegradable Polymersomes. J Am Chem Soc. 2016 08 03; 138(30):9353-6. PMID: 27374777.
      View in: PubMed
    48. Goldberg AF, Moritz OL, Williams DS. Molecular basis for photoreceptor outer segment architecture. Prog Retin Eye Res. 2016 11; 55:52-81. PMID: 27260426.
      View in: PubMed
    49. Williams DS. Intraductal Papillary Mucinous Neoplasm. J Insur Med. 2016; 46(2):71-74. PMID: 28326874.
      View in: PubMed
    50. Williams DS. Choroidal Nevi. J Insur Med. 2016; 46(1):34-7. PMID: 27562111.
      View in: PubMed
    51. Hazim R, Jiang M, Esteve-Rudd J, Diemer T, Lopes VS, Williams DS. Live-Cell Imaging of Phagosome Motility in Primary Mouse RPE Cells. Adv Exp Med Biol. 2016; 854:751-5. PMID: 26427485.
      View in: PubMed
    52. Volland S, Hughes LC, Kong C, Burgess BL, Linberg KA, Luna G, Zhou ZH, Fisher SK, Williams DS. Three-dimensional organization of nascent rod outer segment disk membranes. Proc Natl Acad Sci U S A. 2015 Dec 01; 112(48):14870-5. PMID: 26578801.
      View in: PubMed
    53. Jiang M, Esteve-Rudd J, Lopes VS, Diemer T, Lillo C, Rump A, Williams DS. Microtubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis. J Cell Biol. 2015 Aug 17; 210(4):595-611. PMID: 26261180.
      View in: PubMed
    54. Volland S, Esteve-Rudd J, Hoo J, Yee C, Williams DS. A comparison of some organizational characteristics of the mouse central retina and the human macula. PLoS One. 2015; 10(4):e0125631. PMID: 25923208.
      View in: PubMed
    55. Lopes VS, Williams DS. Gene Therapy for the Retinal Degeneration of Usher Syndrome Caused by Mutations in MYO7A. Cold Spring Harb Perspect Med. 2015 Jan 20; 5(6). PMID: 25605753.
      View in: PubMed
    56. Williams DS. Hydatid Cysts of the Lung and Liver. J Insur Med. 2015; 45(1):58-60. PMID: 27584810.
      View in: PubMed
    57. Williams DS. Angiomyolipoma. J Insur Med. 2015; 45(2):117-20. PMID: 27584849.
      View in: PubMed
    58. Williams DS. Alpha-1 Antitrypsin Deficiency. J Insur Med. 2015; 45(3-4):163-5. PMID: 27584924.
      View in: PubMed
    59. Eblimit A, Nguyen TM, Chen Y, Esteve-Rudd J, Zhong H, Letteboer S, Van Reeuwijk J, Simons DL, Ding Q, Wu KM, Li Y, Van Beersum S, Moayedi Y, Xu H, Pickard P, Wang K, Gan L, Wu SM, Williams DS, Mardon G, Roepman R, Chen R. Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina. Hum Mol Genet. 2015 Mar 15; 24(6):1584-601. PMID: 25398945.
      View in: PubMed
    60. Frost LS, Lopes VS, Bragin A, Reyes-Reveles J, Brancato J, Cohen A, Mitchell CH, Williams DS, Boesze-Battaglia K. The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium. Mol Neurobiol. 2015 Dec; 52(3):1135-1151. PMID: 25301234.
      View in: PubMed
    61. Gee HY, Ashraf S, Wan X, Vega-Warner V, Esteve-Rudd J, Lovric S, Fang H, Hurd TW, Sadowski CE, Allen SJ, Otto EA, Korkmaz E, Washburn J, Levy S, Williams DS, Bakkaloglu SA, Zolotnitskaya A, Ozaltin F, Zhou W, Hildebrandt F. Mutations in EMP2 cause childhood-onset nephrotic syndrome. Am J Hum Genet. 2014 Jun 05; 94(6):884-90. PMID: 24814193.
      View in: PubMed
    62. Crouse JA, Lopes VS, Sanagustin JT, Keady BT, Williams DS, Pazour GJ. Distinct functions for IFT140 and IFT20 in opsin transport. Cytoskeleton (Hoboken). 2014 May; 71(5):302-10. PMID: 24619649.
      View in: PubMed
    63. Lau LF, Williams DS, Lee ST, Scott AM, Christophi C, Muralidharan V. Metabolic response to preoperative chemotherapy predicts prognosis for patients undergoing surgical resection of colorectal cancer metastatic to the liver. Ann Surg Oncol. 2014 Jul; 21(7):2420-8. PMID: 24595797.
      View in: PubMed
    64. Almenar-Queralt A, Falzone TL, Shen Z, Lillo C, Killian RL, Arreola AS, Niederst ED, Ng KS, Kim SN, Briggs SP, Williams DS, Goldstein LS. UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J Neurosci. 2014 Feb 26; 34(9):3320-39. PMID: 24573290.
      View in: PubMed
    65. Williams DS, Patil AJ, Mann S. Spontaneous structuration in coacervate-based protocells by polyoxometalate-mediated membrane assembly. Small. 2014 May 14; 10(9):1830-40. PMID: 24515342.
      View in: PubMed
    66. Williams DS. CADASIL syndrome. J Insur Med. 2014; 44(2):127-9. PMID: 25816473.
      View in: PubMed
    67. Galea LA, Newman M, Au RS, Leong TY, Williams DS. Development of a silver in situ hybridisation based assay for the determination of ploidy status in molar pregnancy diagnosis. Pathology. 2014 Jan; 46(1):15-20. PMID: 24300715.
      View in: PubMed
    68. Williams DS. Glioblastoma multiforme. J Insur Med. 2014; 44(1):62-4. PMID: 25004601.
      View in: PubMed
    69. Williams DS. Non-compaction cardiomyopathy. J Insur Med. 2014; 44(3):206-8. PMID: 25622394.
      View in: PubMed
    70. Esteve-Rudd J, Lopes VS, Jiang M, Williams DS. In vivo and in vitro monitoring of phagosome maturation in retinal pigment epithelium cells. Adv Exp Med Biol. 2014; 801:85-90. PMID: 24664684.
      View in: PubMed
    71. Lopes VS, Diemer T, Williams DS. Assessment of different virus-mediated approaches for retinal gene therapy of Usher 1B. Adv Exp Med Biol. 2014; 801:725-31. PMID: 24664764.
      View in: PubMed
    72. Ashraf S, Gee HY, Woerner S, Xie LX, Vega-Warner V, Lovric S, Fang H, Song X, Cattran DC, Avila-Casado C, Paterson AD, Nitschké P, Bole-Feysot C, Cochat P, Esteve-Rudd J, Haberberger B, Allen SJ, Zhou W, Airik R, Otto EA, Barua M, Al-Hamed MH, Kari JA, Evans J, Bierzynska A, Saleem MA, Böckenhauer D, Kleta R, El Desoky S, Hacihamdioglu DO, Gok F, Washburn J, Wiggins RC, Choi M, Lifton RP, Levy S, Han Z, Salviati L, Prokisch H, Williams DS, Pollak M, Clarke CF, Pei Y, Antignac C, Hildebrandt F. ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. J Clin Invest. 2013 Dec; 123(12):5179-89. PMID: 24270420.
      View in: PubMed
    73. Mei H, González S, Nakatsu MN, Baclagon ER, Lopes VS, Williams DS, Deng SX. A three-dimensional culture method to expand limbal stem/progenitor cells. Tissue Eng Part C Methods. 2014 May; 20(5):393-400. PMID: 24047104.
      View in: PubMed
    74. Zariwala MA, Gee HY, Kurkowiak M, Al-Mutairi DA, Leigh MW, Hurd TW, Hjeij R, Dell SD, Chaki M, Dougherty GW, Adan M, Spear PC, Esteve-Rudd J, Loges NT, Rosenfeld M, Diaz KA, Olbrich H, Wolf WE, Sheridan E, Batten TF, Halbritter J, Porath JD, Kohl S, Lovric S, Hwang DY, Pittman JE, Burns KA, Ferkol TW, Sagel SD, Olivier KN, Morgan LC, Werner C, Raidt J, Pennekamp P, Sun Z, Zhou W, Airik R, Natarajan S, Allen SJ, Amirav I, Wieczorek D, Landwehr K, Nielsen K, Schwerk N, Sertic J, Köhler G, Washburn J, Levy S, Fan S, Koerner-Rettberg C, Amselem S, Williams DS, Mitchell BJ, Drummond IA, Otto EA, Omran H, Knowles MR, Hildebrandt F. ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6. Am J Hum Genet. 2013 Aug 08; 93(2):336-45. PMID: 23891469.
      View in: PubMed
    75. Frost LS, Lopes VS, Stefano FP, Bragin A, Williams DS, Mitchell CH, Boesze-Battaglia K. Loss of melanoregulin (MREG) enhances cathepsin-D secretion by the retinal pigment epithelium. Vis Neurosci. 2013 May; 30(3):55-64. PMID: 23611523.
      View in: PubMed
    76. Huang X, Li M, Green DC, Williams DS, Patil AJ, Mann S. Interfacial assembly of protein-polymer nano-conjugates into stimulus-responsive biomimetic protocells. Nat Commun. 2013; 4:2239. PMID: 23896993.
      View in: PubMed
    77. Williams DS. Castleman's disease. J Insur Med. 2013; 43(4):256-8. PMID: 24069787.
      View in: PubMed
    78. Crosby J, Treadwell T, Hammerton M, Vasilakis K, Crump MP, Williams DS, Mann S. Stabilization and enhanced reactivity of actinorhodin polyketide synthase minimal complex in polymer-nucleotide coacervate droplets. Chem Commun (Camb). 2012 Dec 18; 48(97):11832-4. PMID: 23099989.
      View in: PubMed
    79. Trubiano JA, Holmes NE, Williams DS, Ng J, Chua K, Howden BP. Coxiella burnetii endocarditis after Q fever vaccination. J Med Microbiol. 2012 Dec; 61(Pt 12):1775-9. PMID: 22956746.
      View in: PubMed
    80. Trivedi D, Colin E, Louie CM, Williams DS. Live-cell imaging evidence for the ciliary transport of rod photoreceptor opsin by heterotrimeric kinesin-2. J Neurosci. 2012 Aug 01; 32(31):10587-93. PMID: 22855808.
      View in: PubMed
    81. Cai MM, McMahon LP, Smith ER, Williams DS, Holt SG. Hyperparathyroidism in chronic kidney disease: complexities within the commonplace. Clin Med (Lond). 2012 Aug; 12(4):333-7. PMID: 22930877.
      View in: PubMed
    82. Da Cruz S, Parone PA, Lopes VS, Lillo C, McAlonis-Downes M, Lee SK, Vetto AP, Petrosyan S, Marsala M, Murphy AN, Williams DS, Spiegelman BM, Cleveland DW. Elevated PGC-1a activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell Metab. 2012 May 02; 15(5):778-86. PMID: 22560226.
      View in: PubMed
    83. Engelhardt M, Tosha C, Lopes VS, Chen B, Nguyen L, Nusinowitz S, Williams DS. Functional and morphological analysis of the subretinal injection of retinal pigment epithelium cells. Vis Neurosci. 2012 Mar; 29(2):83-93. PMID: 22391151.
      View in: PubMed
    84. Arango D, Al-Obaidi S, Williams DS, Dopeso H, Mazzolini R, Corner G, Byun DS, Carr AA, Murone C, Tögel L, Zeps N, Aaltonen LA, Iacopetta B, Mariadason JM. Villin expression is frequently lost in poorly differentiated colon cancer. Am J Pathol. 2012 Apr; 180(4):1509-21. PMID: 22349300.
      View in: PubMed
    85. Williams DS. Leg mass in a 19-year-old Afghan man. J Insur Med. 2012; 43(3):185-7. PMID: 23451621.
      View in: PubMed
    86. Williams DS, Lopes VS. Gene therapy strategies for Usher syndrome type 1B. Adv Exp Med Biol. 2012; 723:235-42. PMID: 22183338.
      View in: PubMed
    87. Williams DS. Abnormal head CT imaging in Iraq. J Insur Med. 2012; 43(2):120-3. PMID: 22876417.
      View in: PubMed
    88. Williams DS. Right-sided endocarditis. J Insur Med. 2012; 43(1):41-3. PMID: 22397131.
      View in: PubMed
    89. Harkewicz R, Du H, Tong Z, Alkuraya H, Bedell M, Sun W, Wang X, Hsu YH, Esteve-Rudd J, Hughes G, Su Z, Zhang M, Lopes VS, Molday RS, Williams DS, Dennis EA, Zhang K. Essential role of ELOVL4 protein in very long chain fatty acid synthesis and retinal function. J Biol Chem. 2012 Mar 30; 287(14):11469-80. PMID: 22199362.
      View in: PubMed
    90. Jacobson SG, Cideciyan AV, Gibbs D, Sumaroka A, Roman AJ, Aleman TS, Schwartz SB, Olivares MB, Russell RC, Steinberg JD, Kenna MA, Kimberling WJ, Rehm HL, Williams DS. Retinal disease course in Usher syndrome 1B due to MYO7A mutations. Invest Ophthalmol Vis Sci. 2011 Oct 07; 52(11):7924-36. PMID: 21873662.
      View in: PubMed
    91. Williams DS, Lopes VS. The many different cellular functions of MYO7A in the retina. Biochem Soc Trans. 2011 Oct; 39(5):1207-10. PMID: 21936790.
      View in: PubMed
    92. Byun DS, Ahmed N, Nasser S, Shin J, Al-Obaidi S, Goel S, Corner GA, Wilson AJ, Flanagan DJ, Williams DS, Augenlicht LH, Vincan E, Mariadason JM. Intestinal epithelial-specific PTEN inactivation results in tumor formation. Am J Physiol Gastrointest Liver Physiol. 2011 Nov; 301(5):G856-64. PMID: 21836055.
      View in: PubMed
    93. Koga S, Williams DS, Perriman AW, Mann S. Peptide-nucleotide microdroplets as a step towards a membrane-free protocell model. Nat Chem. 2011 Aug 07; 3(9):720-4. PMID: 21860462.
      View in: PubMed
    94. Phillips JB, Blanco-Sanchez B, Lentz JJ, Tallafuss A, Khanobdee K, Sampath S, Jacobs ZG, Han PF, Mishra M, Titus TA, Williams DS, Keats BJ, Washbourne P, Westerfield M. Harmonin (Ush1c) is required in zebrafish Müller glial cells for photoreceptor synaptic development and function. Dis Model Mech. 2011 Nov; 4(6):786-800. PMID: 21757509.
      View in: PubMed
    95. Lopes VS, Gibbs D, Libby RT, Aleman TS, Welch DL, Lillo C, Jacobson SG, Radu RA, Steel KP, Williams DS. The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65. Hum Mol Genet. 2011 Jul 01; 20(13):2560-70. PMID: 21493626.
      View in: PubMed
    96. Williams DS. Cryoglobulinemia. J Insur Med. 2011; 42(2-4):97-9. PMID: 21888196.
      View in: PubMed
    97. Williams DS, Bird MJ, Jorissen RN, Yu YL, Walker F, Walker F, Zhang HH, Nice EC, Burgess AW. Nonsense mediated decay resistant mutations are a source of expressed mutant proteins in colon cancer cell lines with microsatellite instability. PLoS One. 2010 Dec 31; 5(12):e16012. PMID: 21209843.
      View in: PubMed
    98. Lopes VS, Jimeno D, Khanobdee K, Song X, Chen B, Nusinowitz S, Williams DS. Dysfunction of heterotrimeric kinesin-2 in rod photoreceptor cells and the role of opsin mislocalization in rapid cell death. Mol Biol Cell. 2010 Dec; 21(23):4076-88. PMID: 20926680.
      View in: PubMed
    99. Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, Coene KL, Estrada-Cuzcano A, Collin RW, McLaughlin HM, Held S, Kasanuki JM, Ramaswami G, Conte J, Lopez I, Washburn J, Macdonald J, Hu J, Yamashita Y, Maher ER, Guay-Woodford LM, Neumann HP, Obermüller N, Koenekoop RK, Bergmann C, Bei X, Lewis RA, Katsanis N, Lopes V, Williams DS, Lyons RH, Dang CV, Brito DA, Dias MB, Zhang X, Cavalcoli JD, Nürnberg G, Nürnberg P, Pierce EA, Jackson PK, Antignac C, Saunier S, Roepman R, Dollfus H, Khanna H, Hildebrandt F. Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet. 2010 Oct; 42(10):840-50. PMID: 20835237.
      View in: PubMed
    100. Liao JL, Yu J, Huang K, Hu J, Diemer T, Ma Z, Dvash T, Yang XJ, Travis GH, Williams DS, Bok D, Fan G. Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells. Hum Mol Genet. 2010 Nov 01; 19(21):4229-38. PMID: 20709808.
      View in: PubMed
    101. Perriman AW, Williams DS, Jackson AJ, Grillo I, Koomullil JM, Ghasparian A, Robinson JA, Mann S. Synthetic viruslike particles and hybrid constructs based on lipopeptide self-assembly. Small. 2010 Jun 06; 6(11):1191-6. PMID: 20461723.
      View in: PubMed
    102. Louie CM, Caridi G, Lopes VS, Brancati F, Kispert A, Lancaster MA, Schlossman AM, Otto EA, Leitges M, Gröne HJ, Lopez I, Gudiseva HV, O'Toole JF, Vallespin E, Ayyagari R, Ayuso C, Cremers FP, den Hollander AI, Koenekoop RK, Dallapiccola B, Ghiggeri GM, Hildebrandt F, Valente EM, Williams DS, Gleeson JG. AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis. Nat Genet. 2010 Feb; 42(2):175-80. PMID: 20081859.
      View in: PubMed
    103. Trivedi D, Williams DS. Ciliary transport of opsin. Adv Exp Med Biol. 2010; 664:185-91. PMID: 20238016.
      View in: PubMed
    104. Williams DS. Ramsay Hunt syndrome. J Insur Med. 2010; 42(1):41-3. PMID: 21290999.
      View in: PubMed
    105. Schwander M, Lopes V, Sczaniecka A, Gibbs D, Lillo C, Delano D, Tarantino LM, Wiltshire T, Williams DS, Müller U. A novel allele of myosin VIIa reveals a critical function for the C-terminal FERM domain for melanosome transport in retinal pigment epithelial cells. J Neurosci. 2009 Dec 16; 29(50):15810-8. PMID: 20016096.
      View in: PubMed
    106. Avasthi P, Watt CB, Williams DS, Le YZ, Li S, Chen CK, Marc RE, Frederick JM, Baehr W. Trafficking of membrane proteins to cone but not rod outer segments is dependent on heterotrimeric kinesin-II. J Neurosci. 2009 Nov 11; 29(45):14287-98. PMID: 19906976.
      View in: PubMed
    107. Brownstein CA, Brownstein JS, Williams DS, Wicks P, Heywood JA. The power of social networking in medicine. Nat Biotechnol. 2009 Oct; 27(10):888-90. PMID: 19816437.
      View in: PubMed
    108. Williams DS, Cash A, Hamadani L, Diemer T. Oxaloacetate supplementation increases lifespan in Caenorhabditis elegans through an AMPK/FOXO-dependent pathway. Aging Cell. 2009 Dec; 8(6):765-8. PMID: 19793063.
      View in: PubMed
    109. Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V. Sunday driver interacts with two distinct classes of axonal organelles. J Biol Chem. 2009 Dec 11; 284(50):34628-39. PMID: 19801628.
      View in: PubMed
    110. Gibbs D, Diemer T, Khanobdee K, Hu J, Bok D, Williams DS. Function of MYO7A in the human RPE and the validity of shaker1 mice as a model for Usher syndrome 1B. Invest Ophthalmol Vis Sci. 2010 Feb; 51(2):1130-5. PMID: 19643958.
      View in: PubMed
    111. Falzone TL, Stokin GB, Lillo C, Rodrigues EM, Westerman EL, Williams DS, Goldstein LS. Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects. J Neurosci. 2009 May 06; 29(18):5758-67. PMID: 19420244.
      View in: PubMed
    112. Williams DS, Aleman TS, Lillo C, Lopes VS, Hughes LC, Stone EM, Jacobson SG. Harmonin in the murine retina and the retinal phenotypes of Ush1c-mutant mice and human USH1C. Invest Ophthalmol Vis Sci. 2009 Aug; 50(8):3881-9. PMID: 19324851.
      View in: PubMed
    113. Gibbs D, Cideciyan AV, Jacobson SG, Williams DS. Retinal pigment epithelium defects in humans and mice with mutations in MYO7A: imaging melanosome-specific autofluorescence. Invest Ophthalmol Vis Sci. 2009 Sep; 50(9):4386-93. PMID: 19324852.
      View in: PubMed
    114. Damek-Poprawa M, Diemer T, Lopes VS, Lillo C, Harper DC, Marks MS, Wu Y, Sparrow JR, Rachel RA, Williams DS, Boesze-Battaglia K. Melanoregulin (MREG) modulates lysosome function in pigment epithelial cells. J Biol Chem. 2009 Apr 17; 284(16):10877-89. PMID: 19240024.
      View in: PubMed
    115. Williams DS. Myocardial bridging. J Insur Med. 2009; 41(2):147-50. PMID: 19845219.
      View in: PubMed
    116. Williams DS. Malaria. J Insur Med. 2009; 41(3):221-4. PMID: 20377104.
      View in: PubMed
    117. Williams DS. Prinzmetal angina. J Insur Med. 2009; 41(1):77-9. PMID: 19518010.
      View in: PubMed
    118. Stokin GB, Almenar-Queralt A, Gunawardena S, Rodrigues EM, Falzone T, Kim J, Lillo C, Mount SL, Roberts EA, McGowan E, Williams DS, Goldstein LS. Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. Hum Mol Genet. 2008 Nov 15; 17(22):3474-86. PMID: 18694898.
      View in: PubMed
    119. Yang Z, Chen Y, Lillo C, Chien J, Yu Z, Michaelides M, Klein M, Howes KA, Li Y, Kaminoh Y, Chen H, Zhao C, Chen Y, Al-Sheikh YT, Karan G, Corbeil D, Escher P, Kamaya S, Li C, Johnson S, Frederick JM, Zhao Y, Wang C, Cameron DJ, Huttner WB, Schorderet DF, Munier FL, Moore AT, Birch DG, Baehr W, Hunt DM, Williams DS, Zhang K. Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice. J Clin Invest. 2008 Aug; 118(8):2908-16. PMID: 18654668.
      View in: PubMed
    120. Jacobson SG, Cideciyan AV, Aleman TS, Sumaroka A, Roman AJ, Gardner LM, Prosser HM, Mishra M, Bech-Hansen NT, Herrera W, Schwartz SB, Liu XZ, Kimberling WJ, Steel KP, Williams DS. Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism. Hum Mol Genet. 2008 Aug 01; 17(15):2405-15. PMID: 18463160.
      View in: PubMed
    121. Allocca M, Doria M, Petrillo M, Colella P, Garcia-Hoyos M, Gibbs D, Kim SR, Maguire A, Rex TS, Di Vicino U, Cutillo L, Sparrow JR, Williams DS, Bennett J, Auricchio A. Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice. J Clin Invest. 2008 May; 118(5):1955-64. PMID: 18414684.
      View in: PubMed
    122. Feathers KL, Lyubarsky AL, Khan NW, Teofilo K, Swaroop A, Williams DS, Pugh EN, Thompson DA. Nrl-knockout mice deficient in Rpe65 fail to synthesize 11-cis retinal and cone outer segments. Invest Ophthalmol Vis Sci. 2008 Mar; 49(3):1126-35. PMID: 18326740.
      View in: PubMed
    123. Williams DS. Schistosomiasis. J Insur Med. 2008; 40(3-4):248-9. PMID: 19317335.
      View in: PubMed
    124. Williams DS. Maffucci's syndrome. J Insur Med. 2008; 40(2):146-7. PMID: 19119596.
      View in: PubMed
    125. Diemer T, Gibbs D, Williams DS. Analysis of the rate of disk membrane digestion by cultured RPE cells. Adv Exp Med Biol. 2008; 613:321-6. PMID: 18188960.
      View in: PubMed
    126. Williams DS. Tuberculosis. J Insur Med. 2008; 40(1):72-7. PMID: 18924371.
      View in: PubMed
    127. Krause KJ, Williams DS, White N. Baseline distribution and correlation analysis of hsCRP in an insurance applicant population. J Insur Med. 2008; 40(2):124-9. PMID: 19119592.
      View in: PubMed
    128. Williams DS. Usher syndrome: animal models, retinal function of Usher proteins, and prospects for gene therapy. Vision Res. 2008 Feb; 48(3):433-41. PMID: 17936325.
      View in: PubMed
    129. Klomp AE, Teofilo K, Legacki E, Williams DS. Analysis of the linkage of MYRIP and MYO7A to melanosomes by RAB27A in retinal pigment epithelial cells. Cell Motil Cytoskeleton. 2007 Jun; 64(6):474-87. PMID: 17352418.
      View in: PubMed
    130. Boesze-Battaglia K, Song H, Sokolov M, Lillo C, Pankoski-Walker L, Gretzula C, Gallagher B, Rachel RA, Jenkins NA, Copeland NG, Morris F, Jacob J, Yeagle P, Williams DS, Damek-Poprawa M. The tetraspanin protein peripherin-2 forms a complex with melanoregulin, a putative membrane fusion regulator. Biochemistry. 2007 Feb 06; 46(5):1256-72. PMID: 17260955.
      View in: PubMed
    131. Williams DS. Extra-adrenal pheochromocytoma. J Insur Med. 2007; 39(3):214-6. PMID: 18251381.
      View in: PubMed
    132. Williams DS. Dermatomyositis. J Insur Med. 2007; 39(1):47-50. PMID: 17500358.
      View in: PubMed
    133. Williams DS. Porphyria cutanea tarda. J Insur Med. 2007; 39(4):293-5. PMID: 18522149.
      View in: PubMed
    134. Williams DS. Cardiac hemangioma. J Insur Med. 2007; 39(2):135-7. PMID: 17941339.
      View in: PubMed
    135. Jimeno D, Feiner L, Lillo C, Teofilo K, Goldstein LS, Pierce EA, Williams DS. Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre. Invest Ophthalmol Vis Sci. 2006 Nov; 47(11):5039-46. PMID: 17065525.
      View in: PubMed
    136. Sayer JA, Otto EA, O'Toole JF, Nurnberg G, Kennedy MA, Becker C, Hennies HC, Helou J, Attanasio M, Fausett BV, Utsch B, Khanna H, Liu Y, Drummond I, Kawakami I, Kusakabe T, Tsuda M, Ma L, Lee H, Larson RG, Allen SJ, Wilkinson CJ, Nigg EA, Shou C, Lillo C, Williams DS, Hoppe B, Kemper MJ, Neuhaus T, Parisi MA, Glass IA, Petry M, Kispert A, Gloy J, Ganner A, Walz G, Zhu X, Goldman D, Nurnberg P, Swaroop A, Leroux MR, Hildebrandt F. The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat Genet. 2006 Jun; 38(6):674-81. PMID: 16682973.
      View in: PubMed
    137. Chang B, Khanna H, Hawes N, Jimeno D, He S, Lillo C, Parapuram SK, Cheng H, Scott A, Hurd RE, Sayer JA, Otto EA, Attanasio M, O'Toole JF, Jin G, Shou C, Hildebrandt F, Williams DS, Heckenlively JR, Swaroop A. In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse. Hum Mol Genet. 2006 Jun 01; 15(11):1847-57. PMID: 16632484.
      View in: PubMed
    138. Azarian SM, McLeod I, Lillo C, Gibbs D, Yates JR, Williams DS. Proteomic analysis of mature melanosomes from the retinal pigmented epithelium. J Proteome Res. 2006 Mar; 5(3):521-9. PMID: 16512666.
      View in: PubMed
    139. Williams DS. Neurofibromatosis. J Insur Med. 2006; 38(1):69-71. PMID: 16642646.
      View in: PubMed
    140. Williams DS. Bicuspid aortic valve. J Insur Med. 2006; 38(1):72-4. PMID: 16642647.
      View in: PubMed
    141. Williams DS. Hereditary hemorrhagic telangiectasia. J Insur Med. 2006; 38(3):230-2. PMID: 17076147.
      View in: PubMed
    142. Williams DS. Paradoxical embolism with patent foramen ovale. J Insur Med. 2006; 38(4):293-6. PMID: 17323760.
      View in: PubMed
    143. Williams DS. Wegener's granulomatosis. J Insur Med. 2006; 38(4):297-9. PMID: 17323761.
      View in: PubMed
    144. Williams DS. Polyarteritis nodosa. J Insur Med. 2006; 38(2):144-6. PMID: 16845849.
      View in: PubMed
    145. Williams DS. Cutaneous T-cell lymphoma. J Insur Med. 2006; 38(2):147-50. PMID: 16845850.
      View in: PubMed
    146. Williams DS. Hypothenar hammer syndrome. J Insur Med. 2006; 38(3):233-5. PMID: 17076148.
      View in: PubMed
    147. Lillo C, Kitamoto J, Williams DS. Roles and interactions of usher 1 proteins in the outer retina. Adv Exp Med Biol. 2006; 572:341-8. PMID: 17249594.
      View in: PubMed
    148. Jimeno D, Lillo C, Roberts EA, Goldstein LS, Williams DS. Kinesin-2 and photoreceptor cell death: requirement of motor subunits. Exp Eye Res. 2006 Feb; 82(2):351-3. PMID: 16337628.
      View in: PubMed
    149. Zhu X, Wu K, Rife L, Cawley NX, Brown B, Adams T, Teofilo K, Lillo C, Williams DS, Loh YP, Craft CM. Carboxypeptidase E is required for normal synaptic transmission from photoreceptors to the inner retina. J Neurochem. 2005 Dec; 95(5):1351-62. PMID: 16219026.
      View in: PubMed
    150. Khanna H, Hurd TW, Lillo C, Shu X, Parapuram SK, He S, Akimoto M, Wright AF, Margolis B, Williams DS, Swaroop A. RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins. J Biol Chem. 2005 Sep 30; 280(39):33580-7. PMID: 16043481.
      View in: PubMed
    151. Kitamoto J, Libby RT, Gibbs D, Steel KP, Williams DS. Myosin VI is required for normal retinal function. Exp Eye Res. 2005 Jul; 81(1):116-20. PMID: 15978262.
      View in: PubMed
    152. Daniele LL, Lillo C, Lyubarsky AL, Nikonov SS, Philp N, Mears AJ, Swaroop A, Williams DS, Pugh EN. Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse. Invest Ophthalmol Vis Sci. 2005 Jun; 46(6):2156-67. PMID: 15914637.
      View in: PubMed
    153. Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS, Goldstein LS. Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science. 2005 Feb 25; 307(5713):1282-8. PMID: 15731448.
      View in: PubMed
    154. Otto EA, Loeys B, Khanna H, Hellemans J, Sudbrak R, Fan S, Muerb U, O'Toole JF, Helou J, Attanasio M, Utsch B, Sayer JA, Lillo C, Jimeno D, Coucke P, De Paepe A, Reinhardt R, Klages S, Tsuda M, Kawakami I, Kusakabe T, Omran H, Imm A, Tippens M, Raymond PA, Hill J, Beales P, He S, Kispert A, Margolis B, Williams DS, Swaroop A, Hildebrandt F. Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin. Nat Genet. 2005 Mar; 37(3):282-8. PMID: 15723066.
      View in: PubMed
    155. Williams DS. Acanthosis nigricans. J Insur Med. 2005; 37(2):166-7. PMID: 16060550.
      View in: PubMed
    156. Williams DS. Chronic cutaneous (discoid) lupus erythematosus. J Insur Med. 2005; 37(1):70-1. PMID: 15895703.
      View in: PubMed
    157. Williams DS. Arrhythmogenic right ventricular dysplasia. J Insur Med. 2005; 37(3):243-7. PMID: 16259215.
      View in: PubMed
    158. Gibbs D, Azarian SM, Lillo C, Kitamoto J, Klomp AE, Steel KP, Libby RT, Williams DS. Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes. J Cell Sci. 2004 Dec 15; 117(Pt 26):6473-83. PMID: 15572405.
      View in: PubMed
    159. Libby RT, Lillo C, Kitamoto J, Williams DS, Steel KP. Myosin Va is required for normal photoreceptor synaptic activity. J Cell Sci. 2004 Sep 01; 117(Pt 19):4509-15. PMID: 15316067.
      View in: PubMed
    160. Liu J, Lillo C, Jonsson PA, Vande Velde C, Ward CM, Miller TM, Subramaniam JR, Rothstein JD, Marklund S, Andersen PM, Brännström T, Gredal O, Wong PC, Williams DS, Cleveland DW. Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria. Neuron. 2004 Jul 08; 43(1):5-17. PMID: 15233913.
      View in: PubMed
    161. Siemens J, Lillo C, Dumont RA, Reynolds A, Williams DS, Gillespie PG, Müller U. Cadherin 23 is a component of the tip link in hair-cell stereocilia. Nature. 2004 Apr 29; 428(6986):950-5. PMID: 15057245.
      View in: PubMed
    162. Williams DS. Pemphigus. J Insur Med. 2004; 36(3):267-8. PMID: 15495443.
      View in: PubMed
    163. Libby RT, Kitamoto J, Holme RH, Williams DS, Steel KP. Cdh23 mutations in the mouse are associated with retinal dysfunction but not retinal degeneration. Exp Eye Res. 2003 Dec; 77(6):731-9. PMID: 14609561.
      View in: PubMed
    164. Adams RA, Liu X, Williams DS, Newton AC. Differential spatial and temporal phosphorylation of the visual receptor, rhodopsin, at two primary phosphorylation sites in mice exposed to light. Biochem J. 2003 Sep 01; 374(Pt 2):537-43. PMID: 12809555.
      View in: PubMed
    165. Macdonald WA, Purcell AW, Mifsud NA, Ely LK, Williams DS, Chang L, Gorman JJ, Clements CS, Kjer-Nielsen L, Koelle DM, Burrows SR, Tait BD, Holdsworth R, Brooks AG, Lovrecz GO, Lu L, Rossjohn J, McCluskey J. A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition. J Exp Med. 2003 Sep 01; 198(5):679-91. PMID: 12939341.
      View in: PubMed
    166. Gibbs D, Kitamoto J, Williams DS. Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6481-6. PMID: 12743369.
      View in: PubMed
    167. Xia CH, Roberts EA, Her LS, Liu X, Williams DS, Cleveland DW, Goldstein LS. Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A. J Cell Biol. 2003 Apr 14; 161(1):55-66. PMID: 12682084.
      View in: PubMed
    168. Gibbs D, Williams DS. Isolation and culture of primary mouse retinal pigmented epithelial cells. Adv Exp Med Biol. 2003; 533:347-52. PMID: 15180284.
      View in: PubMed
    169. Williams DS. Cocaine revisited. J Insur Med. 2003; 35(3-4):193-5. PMID: 14971093.
      View in: PubMed
    170. Lillo C, Kitamoto J, Liu X, Quint E, Steel KP, Williams DS. Mouse models for Usher syndrome 1B. Adv Exp Med Biol. 2003; 533:143-50. PMID: 15180258.
      View in: PubMed
    171. Slatter T, Azarian SM, Tebbutt S, Maw M, Williams DS. Screen for usher syndrome 1B mutations in the ovine myosin VIIa gene. Adv Exp Med Biol. 2003; 533:151-5. PMID: 15180259.
      View in: PubMed
    172. Macdonald W, Williams DS, Clements CS, Gorman JJ, Kjer-Nielsen L, Brooks AG, McCluskey J, Rossjohn J, Purcell AW. Identification of a dominant self-ligand bound to three HLA B44 alleles and the preliminary crystallographic analysis of recombinant forms of each complex. FEBS Lett. 2002 Sep 11; 527(1-3):27-32. PMID: 12220628.
      View in: PubMed
    173. Williams DS. Transport to the photoreceptor outer segment by myosin VIIa and kinesin II. Vision Res. 2002 Feb; 42(4):455-62. PMID: 11853761.
      View in: PubMed
    174. Udovichenko IP, Gibbs D, Williams DS. Actin-based motor properties of native myosin VIIa. J Cell Sci. 2002 Jan 15; 115(Pt 2):445-50. PMID: 11839794.
      View in: PubMed
    175. Williams DS. Ventricular septal defects in adults. J Insur Med. 2002; 34(1):68-9. PMID: 15303595.
      View in: PubMed