Sophie X Deng

Title(s)Professor, Ophthalmology
SchoolMedicine
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    Sophie X. Deng, M.D., Ph.D., holds the Joan and Jerome Snyder Chair in Cornea Diseases.

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    Collapse Research Activities and Funding
    Development of small-molecule Wnt mimetics for corneal epithelial cell regeneration
    NIH R01EY028557Sep 30, 2018 - Aug 31, 2022
    Role: Co-Principal Investigator
    Development of stem cell-based therapies for limbal stem cell deficiency
    NIH R01EY021797Sep 1, 2012 - Jan 31, 2024
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Single mRNA detection of Wnt signaling pathway in the human limbus. Exp Eye Res. 2023 04; 229:109337. Bonnet C, Ruiz M, Gonzalez S, Tseng CH, Bourges JL, Behar-Cohen F, Deng SX. PMID: 36702232.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Future regenerative therapies for corneal disease. Curr Opin Ophthalmol. 2023 Jan 06. Lee JY, Knight RJ, Deng SX. PMID: 36602407.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Stability and Function of Extracellular Vesicles Derived from Immortalized Human Corneal Stromal Stem Cells: A Proof of Concept Study. AAPS J. 2022 12 05; 25(1):8. Lyu N, Knight R, Robertson SYT, Dos Santos A, Zhang C, Ma C, Xu J, Zheng J, Deng SX. PMID: 36471035.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Generation of Functional Immortalized Human Corneal Stromal Stem Cells. Int J Mol Sci. 2022 Nov 02; 23(21). Dos Santos A, Lyu N, Balayan A, Knight R, Zhuo KS, Sun Y, Xu J, Funderburgh ML, Funderburgh JL, Deng SX. PMID: 36362184; PMCID: PMC9657819.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Autologous Serum Eye Drops in the Management of Limbal Stem Cell Deficiency Associated With Glaucoma Surgery. Eye Contact Lens. 2022 Nov 02. Niruthisard D, Bonnet C, Tanasugarn L, Le B, Deng SX. PMID: 36322388.
      View in: PubMed   Mentions:    Fields:    
    6. Comment on: Long-Term Outcome After Superficial Keratectomy of the Abnormal Epithelium for Partial Limbal Stem Cell Deficiency. Am J Ophthalmol. 2022 06; 238:202-203. Bonnet C, Tseng CH, Kruse F, Deng SX. PMID: 35296409; PMCID: PMC9636845.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. R-etodolac is a more potent Wnt signaling inhibitor than enantiomer, S-etodolac. Biochem Biophys Rep. 2022 Jul; 30:101231. Roberts JS, Ma C, Robertson SYT, Kang S, Han CS, Deng SX, Zheng JJ. PMID: 35243012; PMCID: PMC8861132.
      View in: PubMed   Mentions:
    8. Rapid 3D bioprinting of a multicellular model recapitulating pterygium microenvironment. Biomaterials. 2022 03; 282:121391. Zhong Z, Wang J, Tian J, Deng X, Balayan A, Sun Y, Xiang Y, Guan J, Schimelman J, Hwang H, You S, Wu X, Ma C, Shi X, Yao E, Deng SX, Chen S. PMID: 35101743.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. 650 GHz imaging as alignment verification for millimeter wave corneal reflectometry. IEEE Trans Terahertz Sci Technol. 2022 Mar; 12(2):151-164. Hu Y, Baggio M, Dabironezare S, Tamminen A, Toy B, Ala-Laurinaho J, Brown E, Llombart N, Deng SX, Wallace V, Taylor ZD. PMID: 36185397; PMCID: PMC9518788.
      View in: PubMed   Mentions: 3  
    10. Cell Morphology as an In Vivo Parameter for the Diagnosis of Limbal Stem Cell Deficiency. Cornea. 2022 Aug 01; 41(8):995-1001. Bonnet C, Chauhan T, Encampira Luna E, Le Q, Tseng CH, Deng SX. PMID: 34935665; PMCID: PMC9218010.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Biomarkers of in vivo limbal stem cell function. Ocul Surf. 2022 01; 23:123-130. Le Q, Chauhan T, Cordova D, Tseng CH, Deng SX. PMID: 34902592.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    12. Regulation of Limbal Epithelial Stem Cells: Importance of the Niche. Int J Mol Sci. 2021 Nov 05; 22(21). Robertson SYT, Roberts JS, Deng SX. PMID: 34769405; PMCID: PMC8584795.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    13. Cytokeratin 13 Is a New Biomarker for the Diagnosis of Limbal Stem Cell Deficiency. Cornea. 2022 Jul 01; 41(7):867-873. Liang Q, Le Q, Wang L, Cordova D, Baclagon E, Garrido SG, Levin M, Jin Y, Tseng CH, Rao J, Deng SX. PMID: 34743102; PMCID: PMC9065215.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. Clinical outcomes and complications of fluid-filled scleral lens devices for the management of limbal stem cell deficiency. Cont Lens Anterior Eye. 2023 02; 46(1):101528. Bonnet C, Lee A, Shibayama VP, Tseng CH, Deng SX. PMID: 34728142; PMCID: PMC9054946.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    15. Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells. Sci Rep. 2021 10 22; 11(1):20948. Bonnet C, Oh D, Mei H, Robertson S, Chang D, Bourges JL, Behar-Cohen F, Zheng JJ, Deng SX. PMID: 34686698; PMCID: PMC8536737.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    16. Infectious Keratitis Isolates and Susceptibility in Southern California. Cornea. 2022 Sep 01; 41(9):1094-1102. Gupta K, Unhale R, Garner OB, Deng SX, M Fung SS. PMID: 35315617.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    17. Sutured Custom Foldable Silicone Artificial Iris Implantation Combined With Intraocular Lens Implantation and Penetrating Keratoplasty: Safety and Efficacy Outcomes. Cornea. 2021 Oct 01; 40(10):1236-1247. Bonnet C, Vazirnia P, Deng SX, Aldave AJ, Miller KM. PMID: 33086281; PMCID: PMC8423143.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses. Biofabrication. 2021 08 13; 13(4). Zhong Z, Balayan A, Tian J, Xiang Y, Hwang HH, Wu X, Deng X, Schimelman J, Sun Y, Ma C, Dos Santos A, You S, Tang M, Yao E, Shi X, Steinmetz NF, Deng SX, Chen S. PMID: 34330126; PMCID: PMC8716326.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    19. Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine. RSC Chem Biol. 2021 Aug 05; 2(4):1144-1157. Bonnet C, Brahmbhatt A, Deng SX, Zheng JJ. PMID: 34458828; PMCID: PMC8341040.
      View in: PubMed   Mentions: 3  
    20. Human limbal epithelial stem cell regulation, bioengineering and function. Prog Retin Eye Res. 2021 11; 85:100956. Bonnet C, González S, Roberts JS, Robertson SYT, Ruiz M, Zheng J, Deng SX. PMID: 33676006; PMCID: PMC8428188.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    21. Limbal stem cell diseases. Exp Eye Res. 2021 04; 205:108437. Bonnet C, Roberts JS, Deng SX. PMID: 33571530; PMCID: PMC8044031.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    22. Therapeutic Potential of Extracellular Vesicles for the Treatment of Corneal Injuries and Scars. Transl Vis Sci Technol. 2020 11; 9(12):1. Deng SX, Dos Santos A, Gee S. PMID: 33200043; PMCID: PMC7645240.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    23. Mulitmodal Corneal Imaging of Genetically Confirmed Keratitis-Ichthyosis-Deafness Syndrome. Cornea. 2020 Nov; 39(11):1446-1449. Lee Lenis T, Zhang W, Shibayama V, Al-Hashimi S, Aldave AJ, Deng SX, Fung SSM. PMID: 32618851.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Global Consensus on the Management of Limbal Stem Cell Deficiency. Cornea. 2020 Oct; 39(10):1291-1302. Deng SX, Kruse F, Gomes JAP, Chan CC, Daya S, Dana R, Figueiredo FC, Kinoshita S, Rama P, Sangwan V, Slomovic AR, Tan D, and the International Limbal Stem Cell Deficiency Working Group. PMID: 32639314.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    25. Reply to Comment on: Corneal Epithelial Thickness Measured Using AS-OCT as a Diagnostic Parameter for Limbal Stem Cell Deficiency. Am J Ophthalmol. 2020 12; 220:218-219. Liang Q, Tseng CH, Deng SX. PMID: 32896370; PMCID: PMC8693997.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    26. Expansion of Human Limbal Epithelial Stem/Progenitor Cells Using Different Human Sera: A Multivariate Statistical Analysis. Int J Mol Sci. 2020 Aug 25; 21(17). Hernáez-Moya R, González S, Urkaregi A, Pijoan JI, Deng SX, Andollo N. PMID: 32854428; PMCID: PMC7503296.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    27. Role of Jagged1-mediated Notch Signaling Activation in the Differentiation and Stratification of the Human Limbal Epithelium. Cells. 2020 08 22; 9(9). González S, Halabi M, Ju D, Tsai M, Deng SX. PMID: 32842657; PMCID: PMC7564045.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    28. Long-Term Outcomes of Descemet Membrane Endothelial Keratoplasty in Eyes with Prior Glaucoma Surgery. Am J Ophthalmol. 2020 10; 218:288-295. Bonnet C, Ghaffari R, Alkadi T, Law SK, Caprioli J, Yu F, Deng SX. PMID: 32619607.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    29. Corneal Endothelial Decompensation. Klin Monbl Augenheilkd. 2020 Jun; 237(6):745-753. Gupta K, Deng SX. PMID: 32516831.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Intraocular Lens Implantation in the Absence of Zonular Support: An Outcomes and Safety Update: A Report by the American Academy of Ophthalmology. Ophthalmology. 2020 09; 127(9):1234-1258. Shen JF, Deng S, Hammersmith KM, Kuo AN, Li JY, Weikert MP, Shtein RM. PMID: 32507620.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    31. Outcomes of Limbal Stem Cell Transplant: A Meta-analysis. JAMA Ophthalmol. 2020 06 01; 138(6):660-670. Le Q, Chauhan T, Yung M, Tseng CH, Deng SX. PMID: 32324211; PMCID: PMC7180742.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    32. Limbal Stem Cell Deficiency After Glaucoma Surgery. Cornea. 2020 May; 39(5):566-572. Sun Y, Yung M, Huang L, Tseng C, Deng SX. PMID: 31977730; PMCID: PMC8018231.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. A Small-Molecule Wnt Mimic Improves Human Limbal Stem Cell Ex Vivo Expansion. iScience. 2020 May 22; 23(5):101075. Zhang C, Mei H, Robertson SYT, Lee HJ, Deng SX, Zheng JJ. PMID: 32361505; PMCID: PMC7200314.
      View in: PubMed   Mentions: 9  
    34. Corneal Epithelial Thickness Measured Using Anterior Segment Optical Coherence Tomography as a Diagnostic Parameter for Limbal Stem Cell Deficiency. Am J Ophthalmol. 2020 08; 216:132-139. Liang Q, Le Q, Cordova DW, Tseng CH, Deng SX. PMID: 32283095; PMCID: PMC7434708.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    35. Evaluation of Cryopreservation Media for the Preservation of Human Corneal Stromal Stem Cells. Tissue Eng Part C Methods. 2020 01; 26(1):37-43. Sun Y, Dos Santos A, Balayan A, Deng SX. PMID: 31686624.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    36. Reply. Cornea. 2019 12; 38(12):e56-e57. Deng SX, Borderie V, Chan CC, Dana R, Figueiredo FC, Gomes JAP, Pellegrini G, Shimmura S, Kruse FE. PMID: 31517726; PMCID: PMC6870173.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    37. Topical Recombinant Human Nerve Growth Factor (Cenegermin) for Neurotrophic Keratopathy: A Multicenter Randomized Vehicle-Controlled Pivotal Trial. Ophthalmology. 2020 01; 127(1):14-26. Pflugfelder SC, Massaro-Giordano M, Perez VL, Hamrah P, Deng SX, Espandar L, Foster CS, Affeldt J, Seedor JA, Afshari NA, Chao W, Allegretti M, Mantelli F, Dana R. PMID: 31585826.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    38. Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro. Sci Rep. 2019 07 17; 9(1):10373. González S, Uhm H, Deng SX. PMID: 31316119; PMCID: PMC6637172.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    39. Mesenchymal Stem Cells Reduce Corneal Fibrosis and Inflammation via Extracellular Vesicle-Mediated Delivery of miRNA. Stem Cells Transl Med. 2019 11; 8(11):1192-1201. Shojaati G, Khandaker I, Funderburgh ML, Mann MM, Basu R, Stolz DB, Geary ML, Dos Santos A, Deng SX, Funderburgh JL. PMID: 31290598; PMCID: PMC6811691.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    40. Diagnostic criteria for limbal stem cell deficiency before surgical intervention-A systematic literature review and analysis. Surv Ophthalmol. 2020 Jan - Feb; 65(1):32-40. Le Q, Chauhan T, Deng SX. PMID: 31276736; PMCID: PMC6911822.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    41. Differentiation Capacity of Human Mesenchymal Stem Cells into Keratocyte Lineage. Invest Ophthalmol Vis Sci. 2019 07 01; 60(8):3013-3023. Dos Santos A, Balayan A, Funderburgh ML, Ngo J, Funderburgh JL, Deng SX. PMID: 31310658; PMCID: PMC6636549.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    42. Comparison of Endothelial Keratoplasty Techniques in Patients With Prior Glaucoma Surgery: A Case-Matched Study. Am J Ophthalmol. 2019 10; 206:94-101. Lin SR, Prapaipanich P, Yu F, Law SK, Caprioli J, Aldave AJ, Deng SX. PMID: 30935848.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Global Consensus on Definition, Classification, Diagnosis, and Staging of Limbal Stem Cell Deficiency. Cornea. 2019 Mar; 38(3):364-375. Deng SX, Borderie V, Chan CC, Dana R, Figueiredo FC, Gomes JAP, Pellegrini G, Shimmura S, Kruse FE, and The International Limbal Stem Cell Deficiency Working Group. PMID: 30614902; PMCID: PMC6363877.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    44. The application of human amniotic membrane in the surgical management of limbal stem cell deficiency. Ocul Surf. 2019 04; 17(2):221-229. Le Q, Deng SX. PMID: 30633967; PMCID: PMC6529245.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    45. Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro. Invest Ophthalmol Vis Sci. 2019 01 02; 60(1):107-112. González S, Oh D, Baclagon ER, Zheng JJ, Deng SX. PMID: 30640975; PMCID: PMC6333110.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    46. Classification of Limbal Stem Cell Deficiency Using Clinical and Confocal Grading. Cornea. 2019 Jan; 38(1):1-7. Aravena C, Bozkurt K, Chuephanich P, Supiyaphun C, Yu F, Deng SX. PMID: 30371569; PMCID: PMC6279551.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    47. In Vivo Evaluation of the Limbus Using Anterior Segment Optical Coherence Tomography. Transl Vis Sci Technol. 2018 Jul; 7(4):12. Le Q, Cordova D, Xu J, Deng SX. PMID: 30112250; PMCID: PMC6082326.
      View in: PubMed   Mentions: 5     Fields:    
    48. A Case of Corneal Neovascularization Misdiagnosed as Total Limbal Stem Cell Deficiency. Cornea. 2018 Aug; 37(8):1067-1070. Le Q, Samson CM, Deng SX. PMID: 29781927; PMCID: PMC6037563.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    49. THz imaging system for in vivo human cornea. IEEE Trans Terahertz Sci Technol. 2018 Jan; 8(1):27-37. Sung S, Selvin S, Bajwa N, Chantra S, Nowroozi B, Garritano J, Goell J, Li A, Deng SX, Brown E, Grundfest WS, Taylor ZD. PMID: 29430335; PMCID: PMC5805158.
      View in: PubMed   Mentions: 17  
    50. Optical System Design for Noncontact, Normal Incidence, THz Imaging of in vivo Human Cornea. IEEE Trans Terahertz Sci Technol. 2018 Jan; 8(1):1-12. Sung S, Dabironezare S, Llombart N, Selvin S, Bajwa N, Chantra S, Nowroozi B, Garritano J, Goell J, Li A, Deng SX, Brown E, Grundfest WS, Taylor ZD. PMID: 29450106; PMCID: PMC5808441.
      View in: PubMed   Mentions: 8  
    51. The diagnosis of limbal stem cell deficiency. Ocul Surf. 2018 01; 16(1):58-69. Le Q, Xu J, Deng SX. PMID: 29113917; PMCID: PMC5844504.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    52. Human adipose-derived stem cells support the growth of limbal stem/progenitor cells. PLoS One. 2017; 12(10):e0186238. Mei H, González S, Nakatsu MN, Baclagon ER, Chen FV, Deng SX. PMID: 29020119; PMCID: PMC5636133.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    53. Descemet Membrane Endothelial Keratoplasty: Safety and Outcomes: A Report by the American Academy of Ophthalmology. Ophthalmology. 2018 02; 125(2):295-310. Deng SX, Lee WB, Hammersmith KM, Kuo AN, Li JY, Shen JF, Weikert MP, Shtein RM. PMID: 28923499.
      View in: PubMed   Mentions: 76     Fields:    Translation:Humans
    54. TFOS DEWS II Management and Therapy Report. Ocul Surf. 2017 07; 15(3):575-628. Jones L, Downie LE, Korb D, Benitez-Del-Castillo JM, Dana R, Deng SX, Dong PN, Geerling G, Hida RY, Liu Y, Seo KY, Tauber J, Wakamatsu TH, Xu J, Wolffsohn JS, Craig JP. PMID: 28736343.
      View in: PubMed   Mentions: 281     Fields:    Translation:Humans
    55. Genome-wide analysis suggests a differential microRNA signature associated with normal and diabetic human corneal limbus. Sci Rep. 2017 06 14; 7(1):3448. Kulkarni M, Leszczynska A, Wei G, Winkler MA, Tang J, Funari VA, Deng N, Liu Z, Punj V, Deng SX, Ljubimov AV, Saghizadeh M. PMID: 28615632; PMCID: PMC5471258.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    56. Comparative Study of Xenobiotic-Free Media for the Cultivation of Human Limbal Epithelial Stem/Progenitor Cells. Tissue Eng Part C Methods. 2017 04; 23(4):219-227. González S, Chen L, Deng SX. PMID: 28346794; PMCID: PMC5397222.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    57. Outcomes of Descemet Membrane Endothelial Keratoplasty in Patients With Previous Glaucoma Surgery. Cornea. 2017 Mar; 36(3):284-289. Aravena C, Yu F, Deng SX. PMID: 27893525; PMCID: PMC5290193.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    58. Characterization of the Corneal Subbasal Nerve Plexus in Limbal Stem Cell Deficiency. Cornea. 2017 Mar; 36(3):347-352. Chuephanich P, Supiyaphun C, Aravena C, Bozkurt TK, Yu F, Deng SX. PMID: 27941384; PMCID: PMC5290068.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    59. Existence of Normal Limbal Epithelium in Eyes With Clinical Signs of Total Limbal Stem Cell Deficiency. Cornea. 2016 Nov; 35(11):1483-1487. Chan E, Le Q, Codriansky A, Hong J, Xu J, Deng SX. PMID: 27362882; PMCID: PMC5067954.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    60. Correlation between the existence of the palisades of Vogt and limbal epithelial thickness in limbal stem cell deficiency. Clin Exp Ophthalmol. 2017 Apr; 45(3):224-231. Le Q, Yang Y, Deng SX, Xu J. PMID: 27591548; PMCID: PMC5336549.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    61. Reply. Ophthalmology. 2016 07; 123(7):e42-3. Lee WB, Kaufman SC, Deng SX, Shtein RM, Rosenblatt MI. PMID: 27342334.
      View in: PubMed   Mentions:    Fields:    
    62. Effect of Hypoxia-regulated Polo-like Kinase 3 (Plk3) on Human Limbal Stem Cell Differentiation. J Biol Chem. 2016 08 05; 291(32):16519-29. Wang L, González S, Dai W, Deng S, Lu L. PMID: 27281822; PMCID: PMC4974368.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    63. From discovery to approval of an advanced therapy medicinal product-containing stem cells, in the EU. Regen Med. 2016 06; 11(4):407-20. Pellegrini G, Lambiase A, Macaluso C, Pocobelli A, Deng S, Cavallini GM, Esteki R, Rama P. PMID: 27091398; PMCID: PMC5561870.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    64. A 3D culture system enhances the ability of human bone marrow stromal cells to support the growth of limbal stem/progenitor cells. Stem Cell Res. 2016 Mar; 16(2):358-64. González S, Mei H, Nakatsu MN, Baclagon ER, Deng SX. PMID: 26896856; PMCID: PMC4828302.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    65. Identification of presumed pathogenic KRT3 and KRT12 gene mutations associated with Meesmann corneal dystrophy. Mol Vis. 2015; 21:1378-86. Chen JL, Lin BR, Gee KM, Gee JA, Chung DW, Frausto RF, Deng SX, Aldave AJ. PMID: 26788030; PMCID: PMC4704769.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    66. Comparison of ACIOL Retention With IOL Exchange in Patients Undergoing Descemet Stripping Automated Endothelial Keratoplasty. Cornea. 2015 Sep; 34(9):1030-4. Tannan A, Vo RC, Chen JL, Yu F, Deng SX, Aldave AJ. PMID: 26147836.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    67. Epithelial Thinning in Limbal Stem Cell Deficiency. Am J Ophthalmol. 2015 Oct; 160(4):669-77.e4. Chan EH, Chen L, Yu F, Deng SX. PMID: 26163009.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    68. Limbal Basal Cell Density Decreases in Limbal Stem Cell Deficiency. Am J Ophthalmol. 2015 Oct; 160(4):678-84.e4. Chan EH, Chen L, Rao JY, Yu F, Deng SX. PMID: 26149968; PMCID: PMC4958454.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    69. Safety and Efficacy of Lacrimal Drainage System Plugs for Dry Eye Syndrome: A Report by the American Academy of Ophthalmology. Ophthalmology. 2015 Aug; 122(8):1681-7. Marcet MM, Shtein RM, Bradley EA, Deng SX, Meyer DR, Bilyk JR, Yen MT, Lee WB, Mawn LA. PMID: 26038339.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    70. Combined astigmatic keratotomy and conductive keratoplasty to correct high corneal astigmatism. J Cataract Refract Surg. 2015 May; 41(5):1050-6. Sy ME, Kovoor TA, Tannan A, Choi D, Deng SX, Danesh J, Hamilton DR. PMID: 25935339.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    71. Boston Keratoprosthesis: Outcomes and Complications: A Report by the American Academy of Ophthalmology. Ophthalmology. 2015 Jul; 122(7):1504-11. Lee WB, Shtein RM, Kaufman SC, Deng SX, Rosenblatt MI. PMID: 25934510.
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    72. THz and mm-Wave Sensing of Corneal Tissue Water Content: In Vivo Sensing and Imaging Results. IEEE Trans Terahertz Sci Technol. 2015 Mar; 5(2):184-196. Taylor ZD, Garritano J, Sung S, Bajwa N, Bennett DB, Nowroozi B, Tewari P, Sayre JW, Hubschman JP, Deng SX, Brown ER, Grundfest WS. PMID: 26161292; PMCID: PMC4493917.
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    73. THz and mm-Wave Sensing of Corneal Tissue Water Content: Electromagnetic Modeling and Analysis. IEEE Trans Terahertz Sci Technol. 2015 Mar; 5(2):170-183. Taylor ZD, Garritano J, Sung S, Bajwa N, Bennett DB, Nowroozi B, Tewari P, Sayre J, Hubschman JP, Deng S, Brown ER, Grundfest WS. PMID: 26322247; PMCID: PMC4551413.
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    74. Preliminary results of non-contact THz imaging of cornea. Proc SPIE Int Soc Opt Eng. 2015 Feb 07; 9362. Sung S, Garritano J, Bajwa N, Deng S, Hubschman JP, Grundfest WS, Taylor ZD. PMID: 26321784; PMCID: PMC4551114.
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    75. Clinical outcomes of Descemet membrane endothelial keratoplasty using eye bank-prepared tissues. Am J Ophthalmol. 2015 Mar; 159(3):590-6. Deng SX, Sanchez PJ, Chen L. PMID: 25526945.
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    76. Pseudomonas aeruginosa keratitis misdiagnosed as fungal keratitis by in vivo confocal microscopy: a case report. BMC Res Notes. 2014 Dec 13; 7:907. Hong J, Le Q, Deng SX, Cao W, Xu J. PMID: 25495791; PMCID: PMC4417546.
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    77. Corneal epithelial thickness map in long-term soft contact lenses wearers. Optom Vis Sci. 2014 Dec; 91(12):1455-61. Hong J, Qian T, Yang Y, Jiang C, Liu Z, Sun X, Deng SX, Xu J. PMID: 25303838.
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    78. Assessment of corneal epithelial thickness in dry eye patients. Optom Vis Sci. 2014 Dec; 91(12):1446-54. Cui X, Hong J, Wang F, Deng SX, Yang Y, Zhu X, Wu D, Zhao Y, Xu J. PMID: 25279779; PMCID: PMC4302058.
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    79. Ultrastructure of the posterior corneal stroma. Ophthalmology. 2015 Apr; 122(4):693-9. Schlötzer-Schrehardt U, Bachmann BO, Tourtas T, Torricelli AA, Singh A, González S, Mei H, Deng SX, Wilson SE, Kruse FE. PMID: 25458195.
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    80. Human limbal mesenchymal cells support the growth of human corneal epithelial stem/progenitor cells. Invest Ophthalmol Vis Sci. 2014 Oct 02; 55(10):6953-9. Nakatsu MN, González S, Mei H, Deng SX. PMID: 25277234; PMCID: PMC4215742.
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    81. Topical interferon alpha-2b for treatment of noninvasive ocular surface squamous neoplasia with 360° limbal involvement. J Ophthalmic Vis Res. 2014 Oct-Dec; 9(4):423-6. Zarei-Ghanavati S, Alizadeh R, Deng SX. PMID: 25709765; PMCID: PMC4329700.
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    82. Meibomian Gland Alteration in Patients with Primary Chronic Dacryocystitis: An In vivo Confocal Microscopy Study. Curr Eye Res. 2015; 40(8):772-9. Hong J, Yu Z, Cui X, Qian T, Le Q, Wei A, Liu Z, Sun X, Deng SX, Xu J. PMID: 25266812.
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    83. Expression of the HSF4 DNA binding domain-EGFP hybrid gene recreates early childhood lamellar cataract in transgenic mice. Invest Ophthalmol Vis Sci. 2014 Aug 28; 55(11):7227-40. Gangalum RK, Jing Z, Bhat AM, Lee J, Nagaoka Y, Deng SX, Jiang M, Bhat SP. PMID: 25168898; PMCID: PMC4231995.
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    84. Schlemm's canal expands after trabeculectomy in patients with primary angle-closure glaucoma. Invest Ophthalmol Vis Sci. 2014 Aug 12; 55(9):5637-42. Hong J, Yang Y, Wei A, Deng SX, Kong X, Chen J, Girard MJ, Mari JM, Xu J, Sun X. PMID: 25118266; PMCID: PMC4580150.
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    85. Complications related to a cosmetic eye-whitening procedure. Am J Ophthalmol. 2014 Nov; 158(5):967-73. Vo RC, Stafeeva K, Aldave AJ, Stulting RD, Moore Q, Pflugfelder SC, Chungfat NC, Holsclaw DS, Margolis TP, Deng SX. PMID: 25072832.
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    86. Age-related changes in human corneal epithelial thickness measured with anterior segment optical coherence tomography. Invest Ophthalmol Vis Sci. 2014 Jul 22; 55(8):5032-8. Yang Y, Hong J, Deng SX, Xu J. PMID: 25052994.
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    87. Frizzled 7 maintains the undifferentiated state of human limbal stem/progenitor cells. Stem Cells. 2014 Apr; 32(4):938-45. Mei H, Nakatsu MN, Baclagon ER, Deng SX. PMID: 24170316; PMCID: PMC3960362.
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    88. Outcomes after DSEK in 101 eyes with previous trabeculectomy and tube shunt implantation. Cornea. 2014 Mar; 33(3):223-9. Aldave AJ, Chen JL, Zaman AS, Deng SX, Yu F. PMID: 24322807.
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    89. A three-dimensional culture method to expand limbal stem/progenitor cells. Tissue Eng Part C Methods. 2014 May; 20(5):393-400. Mei H, González S, Nakatsu MN, Baclagon ER, Lopes VS, Williams DS, Deng SX. PMID: 24047104; PMCID: PMC4005490.
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    90. Author reply: To PMID 23062647. Ophthalmology. 2013 Oct; 120(10):e70-1. Kaufman SC, Jacobs DS, Lee WB, Deng SX, Rosenblatt MI, Shtein RM. PMID: 24090956.
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    91. Presence of native limbal stromal cells increases the expansion efficiency of limbal stem/progenitor cells in culture. Exp Eye Res. 2013 Nov; 116:169-76. González S, Deng SX. PMID: 24016868; PMCID: PMC3900305.
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    92. Author reply: To PMID 23062647. Ophthalmology. 2013 Sep; 120(9):e60-1. Kaufman SC, Jacobs DS, Lee WB, Deng SX, Rosenblatt MI, Shtein RM. PMID: 24001538.
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    93. Oral acyclovir for herpes simplex blepharoconjunctivitis in children. Ophthalmology. 2013 Jun; 120(6):e28. Hong J, Deng SX, Sun X, Xu J. PMID: 23732061.
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    94. Preferential biological processes in the human limbus by differential gene profiling. PLoS One. 2013; 8(4):e61833. Nakatsu MN, Vartanyan L, Vu DM, Ng MY, Li X, Deng SX. PMID: 23630617; PMCID: PMC3632514.
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    95. A new tonometer--the Corvis ST tonometer: clinical comparison with noncontact and Goldmann applanation tonometers. Invest Ophthalmol Vis Sci. 2013 Jan 23; 54(1):659-65. Hong J, Xu J, Wei A, Deng SX, Cui X, Yu X, Sun X. PMID: 23307970.
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    96. Enrichment of human corneal epithelial stem/progenitor cells by magnetic bead sorting using SSEA4 as a negative marker. Methods Mol Biol. 2013; 1014:71-7. Nakatsu MN, Deng SX. PMID: 23690006.
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    97. Presentation, diagnosis and management of limbal stem cell deficiency. Middle East Afr J Ophthalmol. 2013 Jan-Mar; 20(1):5-10. Sejpal K, Bakhtiari P, Deng SX. PMID: 23580847; PMCID: PMC3617528.
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    98. Identification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells. Hum Mol Genet. 2013 Apr 01; 22(7):1271-9. Chen Y, Huang K, Nakatsu MN, Xue Z, Deng SX, Fan G. PMID: 23257286; PMCID: PMC3596846.
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    99. Extracellular Matrix is an Important Component of Limbal Stem Cell Niche. J Funct Biomater. 2012 Dec 10; 3(4):879-94. Mei H, Gonzalez S, Deng SX. PMID: 24955751; PMCID: PMC4030928.
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    100. Enzymatic vitreolysis with ocriplasmin for vitreomacular traction and macular holes. N Engl J Med. 2012 11 22; 367(21):2053; author reply 2054. Hong J, Deng SX, Xu J. PMID: 23171110.
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    101. Options and adjuvants in surgery for pterygium: a report by the American Academy of Ophthalmology. Ophthalmology. 2013 Jan; 120(1):201-8. Kaufman SC, Jacobs DS, Lee WB, Deng SX, Rosenblatt MI, Shtein RM. PMID: 23062647.
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    102. In vivo confocal microscopic findings in Lisch corneal dystrophy. Cornea. 2012 Apr; 31(4):437-41. Kurbanyan K, Sejpal KD, Aldave AJ, Deng SX. PMID: 22222997; PMCID: PMC8820955.
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    103. Role of CTCF in EGF-induced migration of immortalized human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2012 Feb; 53(2):946-51. Wang L, Deng SX, Lu L. PMID: 22247490; PMCID: PMC3317431.
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    104. Characterization of limbal stem cell deficiency by in vivo laser scanning confocal microscopy: a microstructural approach. Arch Ophthalmol. 2012 Apr; 130(4):440-5. Deng SX, Sejpal KD, Tang Q, Aldave AJ, Lee OL, Yu F. PMID: 22159172; PMCID: PMC3928362.
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    105. Limbal lacuna: a novel limbal structure detected by in vivo laser scanning confocal microscopy. Ophthalmic Surg Lasers Imaging. 2011 Dec 08; 42 Online:e129-31. Zarei-Ghanavati S, Ramirez-Miranda A, Deng SX. PMID: 22150603; PMCID: PMC8819905.
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    106. Outcomes after Descemet stripping endothelial keratoplasty in glaucoma patients with previous trabeculectomy and tube shunt implantation. Cornea. 2011 Dec; 30(12):1304-11. Wiaux C, Baghdasaryan E, Lee OL, Bourges JL, Deng SX, Yu F, Aldave AJ. PMID: 21963858.
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    107. SSEA4 is a potential negative marker for the enrichment of human corneal epithelial stem/progenitor cells. Invest Ophthalmol Vis Sci. 2011 Aug 11; 52(9):6315-20. Truong TT, Huynh K, Nakatsu MN, Deng SX. PMID: 21685344; PMCID: PMC3175983.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    108. Wnt/β-catenin signaling regulates proliferation of human cornea epithelial stem/progenitor cells. Invest Ophthalmol Vis Sci. 2011 Jul 01; 52(7):4734-41. Nakatsu MN, Ding Z, Ng MY, Truong TT, Yu F, Deng SX. PMID: 21357396; PMCID: PMC3175950.
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    109. Keratin 13 is a more specific marker of conjunctival epithelium than keratin 19. Mol Vis. 2011; 17:1652-61. Ramirez-Miranda A, Nakatsu MN, Zarei-Ghanavati S, Nguyen CV, Deng SX. PMID: 21738394; PMCID: PMC3130726.
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    110. Elevated intraocular pressure is a common complication during active microbial keratitis. Am J Ophthalmol. 2011 Oct; 152(4):575-581.e1. Zarei-Ghanavati S, Baghdasaryan E, Ramirez-Miranda A, Nguyen M, Yu F, Lee GJ, Deng SX. PMID: 21683333.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    111. Assessment of limbus and central cornea in patients with keratolimbal allograft transplantation using in vivo laser scanning confocal microscopy: an observational study. Graefes Arch Clin Exp Ophthalmol. 2011 May; 249(5):701-8. Hong J, Zheng T, Xu J, Deng SX, Chen L, Sun X, Le Q, Li Y. PMID: 21267594.
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    112. Nocardia farcinica Infection of a Baerveldt implant and endophthalmitis in a patient with a Boston type I keratoprosthesis. J Glaucoma. 2010 Jun-Jul; 19(5):339-40. Tsui I, Uslan DZ, Hubschman JP, Deng SX. PMID: 19855295.
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    113. The use of voriconazole in the management of post-penetrating keratoplasty Paecilomyces keratitis. J Ocul Pharmacol Ther. 2009 Apr; 25(2):175-7. Deng SX, Kamal KM, Hollander DA. PMID: 19284327.
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    114. Preferential gene expression in the limbus of the vervet monkey. Mol Vis. 2008; 14:2031-41. Ding Z, Dong J, Liu J, Deng SX. PMID: 18989386; PMCID: PMC2579939.
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    115. Ocular TRUST: nationwide antimicrobial susceptibility patterns in ocular isolates. Am J Ophthalmol. 2008 Jun; 145(6):951-958. Asbell PA, Colby KA, Deng S, McDonnell P, Meisler DM, Raizman MB, Sheppard JD, Sahm DF. PMID: 18374299.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCellsPHPublic Health
    116. Methotrexate reduces the complications of endophthalmitis resulting from intravitreal injection compared with dexamethasone in a rabbit model. Invest Ophthalmol Vis Sci. 2006 Apr; 47(4):1516-21. Deng SX, Penland S, Gupta S, Fiscella R, Edward DP, Tessler HH, Goldstein DA. PMID: 16565387.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
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