William F Speier

Title(s)Assistant Adjunct Professor, Radiological Sciences
SchoolMedicine
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    Predicting the Presence of Clinically Significant Thyroid Cancer using Ultrasound Imaging
    NIH R21EB030691Jun 4, 2021 - Mar 31, 2024
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Synthesizing MR Image Contrast Enhancement Using 3D High-resolution ConvNets. IEEE Trans Biomed Eng. 2022 Jul 19; PP. Chen C, Raymond C, Speier W, Jin X, Cloughesy TF, Enzmann D, Ellingson BM, Arnold CW. PMID: 35853075.
      View in: PubMed   Mentions:    Fields:    
    2. PathAL: An Active Learning Framework for Histopathology Image Analysis. IEEE Trans Med Imaging. 2022 05; 41(5):1176-1187. Li W, Li J, Wang Z, Polson J, Sisk AE, Sajed DP, Speier W, Arnold CW. PMID: 34898432; PMCID: PMC9199991.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Sex-based differences in remote monitoring of biometric, psychometric and biomarker indices in stable ischemic heart disease. Biol Sex Differ. 2022 04 11; 13(1):15. Barsky L, Speier W, Fuller G, Cheng S, Kim A, Joung S, Arnold C, Dhawan S, Lopez M, Mastali M, van den Broek I, Wei J, Spiegel B, Van Eyk JE, Bairey Merz CN, Shufelt C. PMID: 35410392; PMCID: PMC8996611.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Attention-Guided Discriminative Region Localization and Label Distribution Learning for Bone Age Assessment. IEEE J Biomed Health Inform. 2022 03; 26(3):1208-1218. Chen C, Chen Z, Jin X, Li L, Speier W, Arnold CW. PMID: 34232898.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Extending Brain-Computer Interface Access with a Multilingual Language Model in the P300 Speller. Brain Comput Interfaces (Abingdon). 2022; 9(1):36-48. Loizidou P, Rios E, Marttini A, Keluo-Udeke O, Soetedjo J, Belay J, Perifanos K, Pouratian N, Speier W. PMID: 35574291; PMCID: PMC9094140.
      View in: PubMed   Mentions:
    6. Refining epileptogenic high-frequency oscillations using deep learning: a reverse engineering approach. Brain Commun. 2022; 4(1):fcab267. Zhang Y, Lu Q, Monsoor T, Hussain SA, Qiao JX, Salamon N, Fallah A, Sim MS, Asano E, Sankar R, Staba RJ, Engel J, Speier W, Roychowdhury V, Nariai H. PMID: 35169696; PMCID: PMC8833577.
      View in: PubMed   Mentions:
    7. High resolution histopathology image generation and segmentation through adversarial training. Med Image Anal. 2022 01; 75:102251. Li W, Li J, Polson J, Wang Z, Speier W, Arnold C. PMID: 34814059.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. A Semi-Supervised Learning Framework to Leverage Proxy Information for Stroke MRI Analysis. Annu Int Conf IEEE Eng Med Biol Soc. 2021 11; 2021:2258-2261. Polson J, Zhang H, Nael K, Salamon N, Yoo B, Kim N, Kang DW, Speier W, Arnold CW. PMID: 34891736.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Machine Learning Prediction of Treatment Outcome in Late-Life Depression. Front Psychiatry. 2021; 12:738494. Grzenda A, Speier W, Siddarth P, Pant A, Krause-Sorio B, Narr K, Lavretsky H. PMID: 34744829; PMCID: PMC8563624.
      View in: PubMed   Mentions: 1  
    10. A Machine Learning Approach to Predict Acute Ischemic Stroke Thrombectomy Reperfusion using Discriminative MR Image Features. IEEE EMBS Int Conf Biomed Health Inform. 2021 Jul; 2021. Zhang H, Polson J, Nael K, Salamon N, Yoo B, Speier W, Arnold C. PMID: 35813219; PMCID: PMC9261292.
      View in: PubMed   Mentions:
    11. Bidirectional Representation Learning From Transformers Using Multimodal Electronic Health Record Data to Predict Depression. IEEE J Biomed Health Inform. 2021 08; 25(8):3121-3129. Meng Y, Speier W, Ong MK, Arnold CW. PMID: 33661740; PMCID: PMC8606118.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Harnessing clinical annotations to improve deep learning performance in prostate segmentation. PLoS One. 2021; 16(6):e0253829. Sarma KV, Raman AG, Dhinagar NJ, Priester AM, Harmon S, Sanford T, Mehralivand S, Turkbey B, Marks LS, Raman SS, Speier W, Arnold CW. PMID: 34170972; PMCID: PMC8232529.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Federated learning improves site performance in multicenter deep learning without data sharing. J Am Med Inform Assoc. 2021 06 12; 28(6):1259-1264. Sarma KV, Harmon S, Sanford T, Roth HR, Xu Z, Tetreault J, Xu D, Flores MG, Raman AG, Kulkarni R, Wood BJ, Choyke PL, Priester AM, Marks LS, Raman SS, Enzmann D, Turkbey B, Speier W, Arnold CW. PMID: 33537772; PMCID: PMC8200268.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    14. Generalizing neural signal-to-text brain-computer interfaces. Biomed Phys Eng Express. 2021 04 30; 7(3). Sheth J, Tankus A, Tran M, Pouratian N, Fried I, Speier W. PMID: 33836507.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Optimizing Spatial Biopsy Sampling for the Detection of Prostate Cancer. J Urol. 2021 09; 206(3):595-603. Raman AG, Sarma KV, Raman SS, Priester AM, Mirak SA, Riskin-Jones HH, Dhinagar N, Speier W, Felker E, Sisk AE, Lu D, Kinnaird A, Reiter RE, Marks LS, Arnold CW. PMID: 33908801; PMCID: PMC8903239.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Intra-domain task-adaptive transfer learning to determine acute ischemic stroke onset time. Comput Med Imaging Graph. 2021 06; 90:101926. Zhang H, Polson JS, Nael K, Salamon N, Yoo B, El-Saden S, Scalzo F, Speier W, Arnold CW. PMID: 33934065.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. HCET: Hierarchical Clinical Embedding With Topic Modeling on Electronic Health Records for Predicting Future Depression. IEEE J Biomed Health Inform. 2021 04; 25(4):1265-1272. Meng Y, Speier W, Ong M, Arnold CW. PMID: 32749975; PMCID: PMC8086808.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. A multi-resolution model for histopathology image classification and localization with multiple instance learning. Comput Biol Med. 2021 04; 131:104253. Li J, Li W, Sisk A, Ye H, Wallace WD, Speier W, Arnold CW. PMID: 33601084; PMCID: PMC7984430.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Semi-automated PIRADS scoring via mpMRI analysis. J Med Imaging (Bellingham). 2020 Nov; 7(6):064501. Dhinagar NJ, Speier W, Sarma KV, Raman A, Kinnaird A, Raman SS, Marks LS, Arnold CW. PMID: 33392358; PMCID: PMC7769753.
      View in: PubMed   Mentions:
    20. Integrating remote monitoring into heart failure patients' care regimen: A pilot study. PLoS One. 2020; 15(11):e0242210. Sohn A, Speier W, Lan E, Aoki K, Fonarow GC, Ong MK, Arnold CW. PMID: 33211733; PMCID: PMC7676713.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Biometric and Psychometric Remote Monitoring and Cardiovascular Risk Biomarkers in Ischemic Heart Disease. J Am Heart Assoc. 2020 09 15; 9(18):e016023. Shufelt CL, Kim A, Joung S, Barsky L, Arnold C, Cheng S, Dhawan S, Fuller G, Speier W, Lopez M, Mastali M, Mouapi K, van den Broek I, Wei J, Spiegel B, Van Eyk JE, Bairey-Merz CN. PMID: 32896202; PMCID: PMC7726999.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Assessment of Heart Failure Patients' Interest in Mobile Health Apps for Self-Care: Survey Study. JMIR Cardio. 2019 Oct 29; 3(2):e14332. Sohn A, Speier W, Lan E, Aoki K, Fonarow G, Ong M, Arnold C. PMID: 31758788; PMCID: PMC6851712.
      View in: PubMed   Mentions: 6  
    23. A protocol integrating remote patient monitoring patient reported outcomes and cardiovascular biomarkers. NPJ Digit Med. 2019; 2:84. Shufelt C, Dzubur E, Joung S, Fuller G, Mouapi KN, Van Den Broek I, Lopez M, Dhawan S, Arnold CW, Speier W, Mastali M, Fu Q, Van Eyk JE, Spiegel B, Merz CNB. PMID: 31508495; PMCID: PMC6722086.
      View in: PubMed   Mentions: 5  
    24. Using Sequential Decision Making to Improve Lung Cancer Screening Performance. IEEE Access. 2019; 7:119403-119419. Petousis P, Winter A, Speier W, Aberle DR, Hsu W, Bui AAT. PMID: 32754420; PMCID: PMC7402617.
      View in: PubMed   Mentions: 1  
    25. A Machine Learning Approach to Classifying Self-Reported Health Status in a Cohort of Patients With Heart Disease Using Activity Tracker Data. IEEE J Biomed Health Inform. 2020 03; 24(3):878-884. Meng Y, Speier W, Shufelt C, Joung S, E Van Eyk J, Bairey Merz CN, Lopez M, Spiegel B, Arnold CW. PMID: 31199276; PMCID: PMC6904535.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    26. Predicting ischemic stroke tissue fate using a deep convolutional neural network on source magnetic resonance perfusion images. J Med Imaging (Bellingham). 2019 Apr; 6(2):026001. Ho KC, Scalzo F, Sarma KV, Speier W, El-Saden S, Arnold C. PMID: 31131293; PMCID: PMC6529818.
      View in: PubMed   Mentions: 5  
    27. A Machine Learning Approach for Classifying Ischemic Stroke Onset Time From Imaging. IEEE Trans Med Imaging. 2019 07; 38(7):1666-1676. Ho KC, Speier W, Zhang H, Scalzo F, El-Saden S, Arnold CW. PMID: 30802855; PMCID: PMC6661120.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    28. Evaluating utility and compliance in a patient-based eHealth study using continuous-time heart rate and activity trackers. J Am Med Inform Assoc. 2018 10 01; 25(10):1386-1391. Speier W, Dzubur E, Zide M, Shufelt C, Joung S, Van Eyk JE, Bairey Merz CN, Lopez M, Spiegel B, Arnold C. PMID: 29850807; PMCID: PMC6188512.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    29. An EM-based semi-supervised deep learning approach for semantic segmentation of histopathological images from radical prostatectomies. Comput Med Imaging Graph. 2018 11; 69:125-133. Li J, Speier W, Ho KC, Sarma KV, Gertych A, Knudsen BS, Arnold CW. PMID: 30243216; PMCID: PMC6173982.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    30. Effect of altering breathing frequency on maximum voluntary ventilation in healthy adults. BMC Pulm Med. 2018 May 24; 18(1):89. Neufeld EV, Dolezal BA, Speier W, Cooper CB. PMID: 29793460; PMCID: PMC5968560.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. ResearchMaps.org for integrating and planning research. PLoS One. 2018; 13(5):e0195271. Matiasz NJ, Wood J, Doshi P, Speier W, Beckemeyer B, Wang W, Hsu W, Silva AJ. PMID: 29723213; PMCID: PMC5933701.
      View in: PubMed   Mentions: 2     Fields:    
    32. Classifying Acute Ischemic Stroke Onset Time using Deep Imaging Features. AMIA Annu Symp Proc. 2017; 2017:892-901. Ho KC, Speier W, El-Saden S, Arnold CW. PMID: 29854156; PMCID: PMC5977679.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    33. Improving P300 Spelling Rate using Language Models and Predictive Spelling. Brain Comput Interfaces (Abingdon). 2018; 5(1):13-22. Speier W, Arnold C, Chandravadia N, Roberts D, Pendekanti S, Pouratian N. PMID: 30560145; PMCID: PMC6294452.
      View in: PubMed   Mentions: 2  
    34. The potential value of probabilistic tractography-based for MR-guided focused ultrasound thalamotomy for essential tremor. Neuroimage Clin. 2018; 17:1019-1027. Tsolaki E, Downes A, Speier W, Elias WJ, Pouratian N. PMID: 29527503; PMCID: PMC5842733.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    35. Readability Assessment of Patient-Centered should be capitalized entered Outcomes Research Institute Public Abstracts in Relation to Accessibility. Epidemiology. 2017 07; 28(4):e37-e38. Hollada JL, Zide M, Speier W, Roter DL. PMID: 28282340.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. A comparison of stimulus types in online classification of the P300 speller using language models. PLoS One. 2017; 12(4):e0175382. Speier W, Deshpande A, Cui L, Chandravadia N, Roberts D, Pouratian N. PMID: 28406932; PMCID: PMC5391014.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    37. Online BCI Typing using Language Model Classifiers by ALS Patients in their Homes. Brain Comput Interfaces (Abingdon). 2017; 4(1-2):114-121. Speier W, Chandravadia N, Roberts D, Pendekanti S, Pouratian N. PMID: 29051907; PMCID: PMC5644496.
      View in: PubMed   Mentions: 8  
    38. Integrating language models into classifiers for BCI communication: a review. J Neural Eng. 2016 06; 13(3):031002. Speier W, Arnold C, Pouratian N. PMID: 27153565; PMCID: PMC5495144.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    39. Using phrases and document metadata to improve topic modeling of clinical reports. J Biomed Inform. 2016 06; 61:260-6. Speier W, Ong MK, Arnold CW. PMID: 27109931; PMCID: PMC4902330.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    40. Evaluating topic model interpretability from a primary care physician perspective. Comput Methods Programs Biomed. 2016 Feb; 124:67-75. Arnold CW, Oh A, Chen S, Speier W. PMID: 26614020; PMCID: PMC4724339.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    41. Patients' Perceptions of Radiation Exposure Associated With Mammography. AJR Am J Roentgenol. 2015 Jul; 205(1):215-21. Hollada J, Speier W, Oshiro T, Marzan-McGill R, Ruehm SG, Bassett LW, Wells C. PMID: 26102402.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    42. Incorporating advanced language models into the P300 speller using particle filtering. J Neural Eng. 2015 Aug; 12(4):046018. Speier W, Arnold CW, Deshpande A, Knall J, Pouratian N. PMID: 26061188; PMCID: PMC4509796.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    43. Prevalence of coronary artery disease evaluated by coronary CT angiography in women with mammographically detected breast arterial calcifications. PLoS One. 2015; 10(4):e0122289. Mostafavi L, Marfori W, Arellano C, Tognolini A, Speier W, Adibi A, Ruehm SG. PMID: 25856075; PMCID: PMC4391859.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    44. Motivating the additional use of external validity: examining transportability in a model of glioblastoma multiforme. AMIA Annu Symp Proc. 2014; 2014:1930-9. Singleton KW, Speier W, Bui AA, Hsu W. PMID: 25954466; PMCID: PMC4419978.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    45. Predicting discharge mortality after acute ischemic stroke using balanced data. AMIA Annu Symp Proc. 2014; 2014:1787-96. Ho KC, Speier W, El-Saden S, Liebeskind DS, Saver JL, Bui AA, Arnold CW. PMID: 25954451; PMCID: PMC4419881.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    46. A method for optimizing EEG electrode number and configuration for signal acquisition in P300 speller systems. Clin Neurophysiol. 2015 Jun; 126(6):1171-1177. Speier W, Deshpande A, Pouratian N. PMID: 25316166; PMCID: PMC4377128.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    47. Integrating language information with a hidden Markov model to improve communication rate in the P300 speller. IEEE Trans Neural Syst Rehabil Eng. 2014 May; 22(3):678-84. Speier W, Arnold C, Lu J, Deshpande A, Pouratian N. PMID: 24760927; PMCID: PMC4205234.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    48. Successful patient recruitment in CT imaging clinical trials: what factors influence patient participation? Acad Radiol. 2014 Jan; 21(1):52-7. Hollada J, Marfori W, Tognolini A, Speier W, Ristow L, Ruehm SG. PMID: 24331264.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    49. Evaluating true BCI communication rate through mutual information and language models. PLoS One. 2013; 8(10):e78432. Speier W, Arnold C, Pouratian N. PMID: 24167623; PMCID: PMC3805537.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    50. Improved P300 speller performance using electrocorticography, spectral features, and natural language processing. Clin Neurophysiol. 2013 Jul; 124(7):1321-8. Speier W, Fried I, Pouratian N. PMID: 23465430; PMCID: PMC3679217.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    51. Automated extraction of reported statistical analyses: towards a logical representation of clinical trial literature. AMIA Annu Symp Proc. 2012; 2012:350-9. Hsu W, Speier W, Taira RK. PMID: 23304305; PMCID: PMC3540551.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    52. Updating annotations with the distributed annotation system and the automated sequence annotation pipeline. Bioinformatics. 2012 Nov 01; 28(21):2858-9. Speier W, Ochs MF. PMID: 22945787; PMCID: PMC3476339.
      View in: PubMed   Mentions: 3     Fields:    
    53. The effects of stimulus timing features on P300 speller performance. Clin Neurophysiol. 2013 Feb; 124(2):306-14. Lu J, Speier W, Hu X, Pouratian N. PMID: 22939456; PMCID: PMC3595069.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    54. Natural language processing with dynamic classification improves P300 speller accuracy and bit rate. J Neural Eng. 2012 Feb; 9(1):016004. Speier W, Arnold C, Lu J, Taira RK, Pouratian N. PMID: 22156110; PMCID: PMC3360927.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    55. OnionTree XML: a format to exchange gene-related probabilities. J Biomol Struct Dyn. 2011 Oct; 29(2):417-23. Favorov A, Lvovs D, Speier W, Parmigiani G, Ochs MF. PMID: 21875159; PMCID: PMC4856015.
      View in: PubMed   Mentions:    Fields:    
    56. Robust skull stripping of clinical glioblastoma multiforme data. Med Image Comput Comput Assist Interv. 2011; 14(Pt 3):659-66. Speier W, Iglesias JE, El-Kara L, Tu Z, Arnold C. PMID: 22003756.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    57. Cost implications of new treatments for advanced colorectal cancer. Cancer. 2009 May 15; 115(10):2081-91. Wong YN, Meropol NJ, Speier W, Sargent D, Goldberg RM, Beck JR. PMID: 19309745; PMCID: PMC2875773.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    58. Is proton beam therapy cost effective in the treatment of adenocarcinoma of the prostate? J Clin Oncol. 2007 Aug 20; 25(24):3603-8. Konski A, Speier W, Hanlon A, Beck JR, Pollack A. PMID: 17704408.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    59. Phosphorylation of Akt (Ser473) predicts poor clinical outcome in oropharyngeal squamous cell cancer. Cancer Epidemiol Biomarkers Prev. 2007 Mar; 16(3):553-8. Yu Z, Weinberger PM, Sasaki C, Egleston BL, Speier WF, Haffty B, Kowalski D, Camp R, Rimm D, Vairaktaris E, Burtness B, Psyrri A. PMID: 17372251.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    60. Application of Bayesian decomposition for analysing microarray data. Bioinformatics. 2002 Apr; 18(4):566-75. Moloshok TD, Klevecz RR, Grant JD, Manion FJ, Speier WF, Ochs MF. PMID: 12016054.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
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