Christopher B Cooper

Title(s)Recalled Professor, Medicine
SchoolMedicine
ORCID ORCID Icon0000-0002-6314-0903 Additional info
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    Other Positions
    Title(s)Senate Emeritus, Medicine

    Title(s)Recalled Professor, Physiology

    Title(s)Senate Emeritus, Physiology


    Collapse Biography 
    Collapse Education and Training
    University of London, London, UKBSc1973Physiology
    University of London, London, UKMD (conferred as MB BS)1976Medicine
    University of London, London, UKPhD (conferred as MD)1991Medicine
    US ECFMG, Philadelphia, USAMD1988Medicine
    University of California, Los Angeles, USAMS2013Clinical Research
    Collapse Awards and Honors
    UCLA2020Edward A Dickson Emeritus Professorship Award
    David Geffen School of Medicine, UCLA2009Sherman M Mellinkoff Faculty Award
    American College of Chest Physicians1997Fellowship
    American College of Sports Medicine1996Fellowship
    Royal College of Physicians of the United Kingdom1994Fellowship
    Fulbright Scholar Program1987Fulbright Scholarship
    Royal College of Physicians of Edinburgh1987Travelling Fellowship
    British Thoracic Society1987Scadding Morriston-Davies Joint Fellowship in Respiratory Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Understanding the Origins of Early COPD (SOURCE)
    NIH/NHLBI R01 HL144718-01A1Jul 1, 2021 - Jun 30, 2026
    Role: Principal Investigator, Physiology Reading Center. Chair, Physiology Working Group
    Description: Extension of the SPIROMICS cohort by recruitment of current and former smokers aged 40-60 years.
    Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and molecular endophenotyping in idiopathic pulmonary fibrosis and interstitial lung diseases
    NIH/NHLBI UG3 HL145266Apr 1, 2020 - Mar 31, 2024
    Role: Principal Investigator. Home Spirometry Sub-Study
    Description: Randomized controlled trial of N-acetyl cysteine in patients with idiopathic pulmonary fibrosis with a TOLLIP genotype
    SPIROMICS II: Biological underpinning of COPD heterogeneity and progression
    NIH/NHLBI U24 HL-18-011Jul 1, 2017 - Sep 30, 2023
    Role: Clinical Site Principal Investigator. Chair, Physiology Working Group
    Description: Identification of sub-phenotypes and biomarkers of COPD that facilitate the development of targeted therapies
    SPIROMICS II – Pulmonary Physiology Reading Center
    NIH/NHLBI HR-08-08Jul 1, 2017 - Sep 30, 2022
    Role: Principal Investigator of the Physiology Reading Center
    Description: Provide administration and quality assurance for physiological measurements including spirometry and oscillometry in SPIROMICS II.

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Vessel and Airway Characteristics in One-Year CT-defined Rapid Emphysema Progression: SPIROMICS. Ann Am Thorac Soc. 2024 Mar 26. Gerard SE, Dougherty TM, Nagpal P, Jin D, Han MK, Newell JD, Saha PK, Comellas AP, Cooper CB, Couper D, Fortis S, Guo J, Hansel NN, Kanner RE, Kazeroni EA, Martinez FJ, Motahari A, Paine Iii R, Rennard S, Schroeder JD, Woodruff PG, Barr RG, Smith BM, Hoffman EA. PMID: 38530051.
      View in: PubMed   Mentions:    Fields:    
    2. The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort. Am J Respir Crit Care Med. 2024 Mar 20. Suri R, Markovic D, Woo H, Arjomandi M, Barr RG, Bowler RP, Criner G, Curtis JL, Dransfield MT, Drummond MB, Fortis S, Han MK, Hoffman EA, Kaner RJ, Kaufman JD, Krishnan JA, Martinez FJ, Ohar J, Ortega VE, Paine Iii R, Soler X, Woodruff PG, Hansel NN, Cooper CB, Tashkin DP, Buhr RG, Barjaktarevic IZ. PMID: 38507607.
      View in: PubMed   Mentions:    Fields:    
    3. Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase. Sci Adv. 2024 Mar 15; 10(11):eadj6406. Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L, Alex A, Roubert C, Gardner M, Preston M, Smith DM, Ling Y, Roberts J, Cautain B, Upton A, Cooper CB, Serbina N, Tanvir Z, Mosior J, Ouerfelli O, Yang G, Gold BS, Rhee KY, Sacchettini JC, Fotouhi N, Aubé J, Nathan C. PMID: 38489355; PMCID: PMC10942122.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. LungViT: Ensembling Cascade of Texture Sensitive Hierarchical Vision Transformers for Cross-Volume Chest CT Image-to-Image Translation. IEEE Trans Med Imaging. 2024 Feb 19; PP. Chaudhary MFA, Gerard SE, Christensen GE, Cooper CB, Schroeder JD, Hoffman EA, Reinhardt JM. PMID: 38373126.
      View in: PubMed   Mentions:    Fields:    
    5. Metronome-Paced Tachypnea: A Simple, Repeatable Method for Inducing Dynamic Hyperinflation. Am J Respir Crit Care Med. 2024 Feb 01; 209(3):337-339. Cooper CB. PMID: 38099723.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Lung Structure and Risk of Sleep Apnea in SPIROMICS. Chronic Obstr Pulm Dis. 2024 Jan 25; 11(1):26-36. Koch AL, Shing TL, Namen A, Couper D, Smith B, Barr RG, Bhatt S, Putcha N, Baugh A, Saha AK, Ziedler M, Comellas A, Cooper CB, Barjaktarevic I, Bowler RP, Han MK, Kim V, Paine R, Kanner RE, Krishnan JA, Martinez FJ, Woodruff PG, Hansel NN, Hoffman EA, Peters SP, Ortega VE, SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS) Investigators. PMID: 37931592; PMCID: PMC10913931.
      View in: PubMed   Mentions:
    7. Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in COPD. Am J Respir Crit Care Med. 2024 Jan 23. Opron K, Begley LA, Erb-Downward JR, Li G, Alexis NE, Barjaktarevic I, Barr RG, Bleecker ER, Boucher R, Bowler RP, Christenson SA, Comellas AP, Criner G, Cooper CB, Couper D, Galban CJ, Han MK, Hastie A, Hatt C, Hoffman EA, Kaner RJ, Kesimer M, Krishnan JA, LaFon DC, Martinez FJ, Ortega VE, Peters SP, Paine Iii R, Putcha N, Woodruff PG, Huffnagle GB, Kozik AJ, Curtis JL, Huang YJ, SPIROMICS Investigators. PMID: 38261629.
      View in: PubMed   Mentions:    Fields:    
    8. Indoor Pollution and Lung Function Decline in Current and Former Smokers: SPIROMICS AIR. Am J Respir Crit Care Med. 2023 Nov 15; 208(10):1042-1051. Hansel NN, Woo H, Koehler K, Gassett A, Paulin LM, Alexis NE, Putcha N, Lorizio W, Fawzy A, Belz D, Sack C, Barr RG, Martinez FJ, Han MK, Woodruff P, Pirozzi C, Paine R, Barjaktarevic I, Cooper CB, Ortega V, Zusman M, Kaufman JD. PMID: 37523421; PMCID: PMC10867935.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    9. Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2023 09 15; 208(6):657-665. Motahari A, Barr RG, Han MK, Anderson WH, Barjaktarevic I, Bleecker ER, Comellas AP, Cooper CB, Couper DJ, Hansel NN, Kanner RE, Kazerooni EA, Lynch DA, Martinez FJ, Newell JD, Schroeder JD, Smith BM, Woodruff PG, Hoffman EA, SPIROMICS Group. PMID: 37490608; PMCID: PMC10515564.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry. JAMA. 2023 08 01; 330(5):442-453. McKleroy W, Shing T, Anderson WH, Arjomandi M, Awan HA, Barjaktarevic I, Barr RG, Bleecker ER, Boscardin J, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Curtis JL, Dransfield M, Doerschuk CM, Dolezal BA, Drummond MB, Han MK, Hansel NN, Helton K, Hoffman EA, Kaner RJ, Kanner RE, Krishnan JA, Lazarus SC, Martinez FJ, Ohar J, Ortega VE, Paine R, Peters SP, Reinhardt JM, Rennard S, Smith BM, Tashkin DP, Couper D, Cooper CB, Woodruff PG. PMID: 37526720; PMCID: PMC10394572.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Changes in Lung Volumes with Spirometric Disease Progression in COPD. Chronic Obstr Pulm Dis. 2023 Jul 26; 10(3):270-285. Arjomandi M, Zeng S, Chen J, Bhatt SP, Abtin F, Barjaktarevic I, Barr RG, Bleecker ER, Buhr RG, Criner GJ, Comellas AP, Couper DJ, Curtis JL, Dransfield MT, Fortis S, Han MK, Hansel NN, Hoffman EA, Hokanson JE, Kaner RJ, Kanner RE, Krishnan JA, Labaki WW, Lynch DA, Ortega VE, Peters SP, Woodruff PG, Cooper CB, Bowler RP, Paine R, Rennard SI, Tashkin DP, and the COPDGene and SPIROMICS Investigators. PMID: 37199719; PMCID: PMC10484496.
      View in: PubMed   Mentions: 3  
    12. Impact of Marijuana Smoking on COPD Progression in a Cohort of Middle-Aged and Older Persons. Chronic Obstr Pulm Dis. 2023 Jul 26; 10(3):234-247. Barjaktarevic I, Cooper CB, Shing T, Buhr RG, Hoffman EA, Woodruff PG, Drummond MB, Kanner RE, Han MK, Hansel NN, Bowler RP, Kinney GL, Jacobson S, Morris MA, Martinez FJ, Ohar J, Couper D, Tashkin DP. PMID: 37199732; PMCID: PMC10484485.
      View in: PubMed   Mentions:
    13. Impact of Bronchiectasis on COPD Severity and Alpha-1 Antitrypsin Deficiency as a Risk Factor in Individuals with a Heavy Smoking History. Chronic Obstr Pulm Dis. 2023 Jul 26; 10(3):199-210. Izquierdo M, Marion CR, Genese F, Newell JD, O'Neal WK, Li X, Hawkins GA, Barjaktarevic I, Barr RG, Christenson S, Cooper CB, Couper D, Curtis J, Han MK, Hansel NN, Kanner RE, Martinez FJ, Paine R, Tejwani V, Woodruff PG, Zein JG, Hoffman EA, Peters SP, Meyers DA, Bleecker ER, Ortega VE, SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS) investigators. PMID: 37199731; PMCID: PMC10484491.
      View in: PubMed   Mentions:
    14. Three-Month Variability of Commonly Evaluated Biomarkers in Clinically Stable COPD. Int J Chron Obstruct Pulmon Dis. 2023; 18:1475-1486. Park SC, Saiphoklang N, Phillips J, Wilgus ML, Buhr RG, Tashkin DP, Cooper CB, Barjaktarevic I. PMID: 37485051; PMCID: PMC10362903.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Autonomous alignment and healing in multilayer soft electronics using immiscible dynamic polymers. Science. 2023 Jun 02; 380(6648):935-941. Cooper CB, Root SE, Michalek L, Wu S, Lai JC, Khatib M, Oyakhire ST, Zhao R, Qin J, Bao Z. PMID: 37262169.
      View in: PubMed   Mentions: 2     Fields:    
    16. A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD. Sci Rep. 2023 05 22; 13(1):8228. DiLillo KM, Norman KC, Freeman CM, Christenson SA, Alexis NE, Anderson WH, Barjaktarevic IZ, Barr RG, Comellas AP, Bleecker ER, Boucher RC, Couper DJ, Criner GJ, Doerschuk CM, Wells JM, Han MK, Hoffman EA, Hansel NN, Hastie AT, Kaner RJ, Krishnan JA, Labaki WW, Martinez FJ, Meyers DA, O'Neal WK, Ortega VE, Paine R, Peters SP, Woodruff PG, Cooper CB, Bowler RP, Curtis JL, Arnold KB, SPIROMICS investigators. PMID: 37217548; PMCID: PMC10203309.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Association of Occupational Exposures and Chronic Obstructive Pulmonary Disease Morbidity. J Occup Environ Med. 2023 07 01; 65(7):e443-e452. Rous JS, Lees PSJ, Koehler K, Buckley JP, Quirós-Alcalá L, Han MK, Hoffman EA, Labaki W, Barr RG, Peters SP, Paine R, Pirozzi C, Cooper CB, Dransfield MT, Comellas AP, Kanner RE, Drummond MB, Putcha N, Hansel NN, Paulin LM. PMID: 36977360; PMCID: PMC10330008.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    18. Predicting severe chronic obstructive pulmonary disease exacerbations using quantitative CT: a retrospective model development and external validation study. Lancet Digit Health. 2023 02; 5(2):e83-e92. Chaudhary MFA, Hoffman EA, Guo J, Comellas AP, Newell JD, Nagpal P, Fortis S, Christensen GE, Gerard SE, Pan Y, Wang D, Abtin F, Barjaktarevic IZ, Barr RG, Bhatt SP, Bodduluri S, Cooper CB, Gravens-Mueller L, Han MK, Kazerooni EA, Martinez FJ, Menchaca MG, Ortega VE, Iii RP, Schroeder JD, Woodruff PG, Reinhardt JM. PMID: 36707189; PMCID: PMC9896720.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Ambient Air Pollution Exposure and Sleep Quality in COPD. Chronic Obstr Pulm Dis. 2023 Jan 25; 10(1):102-111. Sowho MO, Koch AL, Putcha N, Woo H, Gassett A, Paulin LM, Koehler K, Barr RG, Comellas AP, Cooper CB, Barjaktarevic I, Zeidler MR, Billings ME, Bowler RP, Han MK, Kim V, Paine Iii R, Parekh TM, Krishnan JA, Peters SP, Woodruff PG, Baugh AM, Kaufman JD, Couper D, Hansel NN. PMID: 36599095; PMCID: PMC9995229.
      View in: PubMed   Mentions: 1  
    20. A case study of a unique advanced clinical skills elective at the David Geffen School of Medicine at UCLA. MedEdPublish (2016). 2023; 13:1. Lazarus ME, Hernandez EA, Kahn DG, Vigallon S, Cooper CB. PMID: 36819947; PMCID: PMC9926504.
      View in: PubMed   Mentions:
    21. Design and rationale for the prospective treatment efficacy in IPF using genotype for NAC selection (PRECISIONS) clinical trial. BMC Pulm Med. 2022 Dec 13; 22(1):475. Podolanczuk AJ, Kim JS, Cooper CB, Lasky JA, Murray S, Oldham JM, Raghu G, Flaherty KR, Spino C, Noth I, Martinez FJ, PRECISIONS Study Team. PMID: 36514019; PMCID: PMC9746571.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    22. Correlation between Hand Grip Strength and Peak Inspiratory Flow Rate in Patients with Stable Chronic Obstructive Pulmonary Disease. Diagnostics (Basel). 2022 Dec 05; 12(12). Suriyakul A, Saiphoklang N, Barjaktarevic I, Cooper CB. PMID: 36553057; PMCID: PMC9777131.
      View in: PubMed   Mentions: 1  
    23. Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD. Chest. 2023 03; 163(3):502-514. Fortis S, Quibrera PM, Comellas AP, Bhatt SP, Tashkin DP, Hoffman EA, Criner GJ, Han MK, Barr RG, Arjomandi M, Dransfield MB, Peters SP, Dolezal BA, Kim V, Putcha N, Rennard SI, Paine R, Kanner RE, Curtis JL, Bowler RP, Martinez FJ, Hansel NN, Krishnan JA, Woodruff PG, Barjaktarevic IZ, Couper D, Anderson WH, Cooper CB, Subpopulations and Intermediate Outcome Measures in COPD Study Investigators. PMID: 36395858; PMCID: PMC9993341.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS. Respir Res. 2022 Nov 14; 23(1):310. Tejwani V, Woo H, Liu C, Tillery AK, Gassett AJ, Kanner RE, Hoffman EA, Martinez FJ, Woodruff PG, Barr RG, Fawzy A, Koehler K, Curtis JL, Freeman CM, Cooper CB, Comellas AP, Pirozzi C, Paine R, Tashkin D, Krishnan JA, Sack C, Putcha N, Paulin LM, Zusman M, Kaufman JD, Alexis NE, Hansel NN. PMID: 36376879; PMCID: PMC9664618.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    25. Prolonged, physiologically relevant nicotine concentrations in the airways of smokers. Am J Physiol Lung Cell Mol Physiol. 2023 01 01; 324(1):L32-L37. Esther CR, O'Neal WK, Alexis NE, Koch AL, Cooper CB, Barjaktarevic I, Raffield LM, Bowler RP, Comellas AP, Peters SP, Hastie AT, Curtis JL, Ronish B, Ortega VE, Wells JM, Halper-Stromberg E, Rennard SI, Boucher RC, SPIROMICS. PMID: 36342131; PMCID: PMC9829458.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. A novel geometric method for determining the time constant for oxygen uptake kinetics. J Appl Physiol (1985). 2022 11 01; 133(5):1081-1092. Cooper CB, Garfinkel A. PMID: 36135954.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Effect of marijuana smoking on lung function change in older ever tobacco smokers. Eur Respir J. 2022 09; 60(3). Barjaktarevic I, Cooper CB, Shing T, Buhr RG, Hoffman EA, Woodruff PG, Drummond MB, Kanner RE, Han MK, Hansel NN, Bowler RP, Kinney GL, Jacobson S, Morris MA, Martinez FJ, Ohar J, Couper D, Tashkin DP. PMID: 36137583; PMCID: PMC9945875.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Formation Mechanism of Flower-like Polyacrylonitrile Particles. J Am Chem Soc. 2022 09 28; 144(38):17576-17587. Gong H, Ilavsky J, Kuzmenko I, Chen S, Yan H, Cooper CB, Chen G, Chen Y, Chiong JA, Jiang Y, Lai JC, Zheng Y, Stone KH, Huelsenbeck L, Giri G, Tok JB, Bao Z. PMID: 36102706.
      View in: PubMed   Mentions: 1     Fields:    
    29. Synthesis and Structure-Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl-N-(Pyridin-2-ylmethyl)Pyrazolo[1,5-a]Pyrimidin-7-Amines. Pharmaceuticals (Basel). 2022 Sep 08; 15(9). Sutherland HS, Choi PJ, Lu GL, Giddens AC, Tong AST, Franzblau SG, Cooper CB, Palmer BD, Denny WA. PMID: 36145345; PMCID: PMC9506485.
      View in: PubMed   Mentions:
    30. Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function. N Engl J Med. 2022 09 29; 387(13):1173-1184. Han MK, Ye W, Wang D, White E, Arjomandi M, Barjaktarevic IZ, Brown SA, Buhr RG, Comellas AP, Cooper CB, Criner GJ, Dransfield MT, Drescher F, Folz RJ, Hansel NN, Kalhan R, Kaner RJ, Kanner RE, Krishnan JA, Lazarus SC, Maddipati V, Martinez FJ, Mathews A, Meldrum C, McEvoy C, Nyunoya T, Rogers L, Stringer WW, Wendt CH, Wise RA, Wisniewski SR, Sciurba FC, Woodruff PG, RETHINC Study Group. PMID: 36066078; PMCID: PMC9741866.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    31. Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study. Am J Respir Crit Care Med. 2022 09 01; 206(5):554-562. Buhr RG, Barjaktarevic IZ, Quibrera PM, Bateman LA, Bleecker ER, Couper DJ, Curtis JL, Dolezal BA, Han MK, Hansel NN, Krishnan JA, Martinez FJ, McKleroy W, Paine R, Rennard SI, Tashkin DP, Woodruff PG, Kanner RE, Cooper CB, SPIROMICS Investigators. PMID: 35549640; PMCID: PMC9716898.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    32. Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2022 08 15; 206(4):427-439. Madapoosi SS, Cruickshank-Quinn C, Opron K, Erb-Downward JR, Begley LA, Li G, Barjaktarevic I, Barr RG, Comellas AP, Couper DJ, Cooper CB, Freeman CM, Han MK, Kaner RJ, Labaki W, Martinez FJ, Ortega VE, Peters SP, Paine R, Woodruff P, Curtis JL, Huffnagle GB, Stringer KA, Bowler RP, Esther CR, Reisdorph N, Huang YJ, SPIROMICS Research Group. PMID: 35536732.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    33. Association Among Chronic Obstructive Pulmonary Disease Severity, Exacerbation Risk, and Anxiety and Depression Symptoms in the SPIROMICS Cohort. J Acad Consult Liaison Psychiatry. 2023 Jan-Feb; 64(1):45-57. Weiss JR, Serdenes R, Madtha U, Zhao H, Kim V, Lopez-Pastrana J, Eakin MN, O'Toole J, Cooper CB, Woodruff P, Kanner RE, Krishnan JA, Iyer AS, Couper D, Morrison MF. PMID: 35948252.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort. Chronic Obstr Pulm Dis. 2022 Apr 29; 9(2):111-121. Ronish BE, Couper DJ, Barjaktarevic IZ, Cooper CB, Kanner RE, Pirozzi CS, Kim V, Wells JM, Han MK, Woodruff PG, Ortega VE, Peters SP, Hoffman EA, Buhr RG, Dolezal BA, Tashkin DP, Liou TG, Bateman LA, Schroeder JD, Martinez FJ, Barr RG, Hansel NN, Comellas AP, Rennard SI, Arjomandi M, Paine Iii R. PMID: 35114743; PMCID: PMC9166328.
      View in: PubMed   Mentions: 7  
    35. Reconsidering the Utility of Race-Specific Lung Function Prediction Equations. Am J Respir Crit Care Med. 2022 04 01; 205(7):819-829. Baugh AD, Shiboski S, Hansel NN, Ortega V, Barjaktarevic I, Barr RG, Bowler R, Comellas AP, Cooper CB, Couper D, Criner G, Curtis JL, Dransfield M, Ejike C, Han MK, Hoffman E, Krishnan J, Krishnan JA, Mannino D, Paine R, Parekh T, Peters S, Putcha N, Rennard S, Thakur N, Woodruff PG. PMID: 34913855; PMCID: PMC9836221.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    36. Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR. Sci Total Environ. 2022 Jul 10; 829:154694. Belz DC, Woo H, Putcha N, Paulin LM, Koehler K, Fawzy A, Alexis NE, Barr RG, Comellas AP, Cooper CB, Couper D, Dransfield M, Gassett AJ, Han M, Hoffman EA, Kanner RE, Krishnan JA, Martinez FJ, Paine R, Peng RD, Peters S, Pirozzi CS, Woodruff PG, Kaufman JD, Hansel NN, SPIROMICS Investigators. PMID: 35318050; PMCID: PMC9117415.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    37. Use of a Wearable Biosensor to Study Heart Rate Variability in Chronic Obstructive Pulmonary Disease and Its Relationship to Disease Severity. Sensors (Basel). 2022 Mar 15; 22(6). Park SC, Saiphoklang N, Jung D, Gomez D, Phillips JE, Dolezal BA, Tashkin DP, Barjaktarevic I, Cooper CB. PMID: 35336436; PMCID: PMC8952191.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    38. Synthetic studies towards isomeric pyrazolopyrimidines as potential ATP synthesis inhibitors of Mycobacterium tuberculosis. Structural correction of reported N-(6-(2-(dimethylamino)ethoxy)-5-fluoropyridin-3-yl)-2-(4-fluorophenyl)-5-(trifluoromethyl)pyrazolo[1,5-α]pyrimidin-7-amine. Tetrahedron Lett. 2022 Feb 02; 90:None. Choi PJ, Lu GL, Sutherland HS, Giddens AC, Franzblau SG, Cooper CB, Denny WA, Palmer BD. PMID: 35140452; PMCID: PMC8809387.
      View in: PubMed   Mentions: 6     Fields:    
    39. Comparative Impact of Depressive Symptoms and FEV1% on Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2022 02; 19(2):171-178. O'Toole J, Woo H, Putcha N, Cooper CB, Woodruff P, Kanner RE, Paine R, Bowler RP, Comellas A, Hoth KF, Krishnan JA, Han M, Dransfield M, Iyer AS, Couper D, Peters SP, Criner G, Kim V, Barr RG, Martinez FJ, Hansel NN, Eakin MN, SPIROMICS Investigators. PMID: 34410883; PMCID: PMC8867359.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Clinically Significant and Comorbid Anxiety and Depression Symptoms Predict Severe Respiratory Exacerbations in Smokers: A Post Hoc Analysis of the COPDGene and SPIROMICS Cohorts. Ann Am Thorac Soc. 2022 01; 19(1):143-146. Iyer AS, Parekh TM, O'Toole J, Bhatt SP, Eakin MN, Krishnan JA, Yohannes AM, Woodruff PG, Cooper CB, Kanner RE, Hanania NA, Dransfield MT, Regan EA, Hoth KF, Kim V, COPDGene and SPIROMICS Investigators. PMID: 34343034.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    41. Craving among individuals with stimulant use disorder in residential social model-based treatment - Can exercise help? Drug Alcohol Depend. 2022 02 01; 231:109247. Salem BA, Gonzales-Castaneda R, Ang A, Rawson RA, Dickerson D, Chudzynski J, Penate J, Dolezal B, Cooper CB, Mooney LJ. PMID: 34999268; PMCID: PMC10978100.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    42. Synthesis and structure-activity relationships for a new class of tetrahydronaphthalene amide inhibitors of Mycobacterium tuberculosis. Eur J Med Chem. 2022 Feb 05; 229:114059. Sutherland HS, Lu GL, Tong AST, Conole D, Franzblau SG, Upton AM, Lotlikar MU, Cooper CB, Palmer BD, Choi PJ, Denny WA. PMID: 34963068; PMCID: PMC8811485.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    43. Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in COPD. Chest. 2022 05; 161(5):1239-1249. Esther CR, O'Neal WK, Anderson WH, Kesimer M, Ceppe A, Doerschuk CM, Alexis NE, Hastie AT, Barr RG, Bowler RP, Wells JM, Oelsner EC, Comellas AP, Tesfaigzi Y, Kim V, Paulin LM, Cooper CB, Han MK, Huang YJ, Labaki WW, Curtis JL, Boucher RC, Subpopulations and Intermediate Outcome Measures in COPD Study. PMID: 34801592; PMCID: PMC9131049.
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    44. Significance of FEV3/FEV6 in Recognition of Early Airway Disease in Smokers at Risk of Development of COPD: Analysis of the SPIROMICS Cohort. Chest. 2022 04; 161(4):949-959. Yee N, Markovic D, Buhr RG, Fortis S, Arjomandi M, Couper D, Anderson WH, Paine R, Woodruff PG, Han MK, Martinez FJ, Barr RG, Wells JM, Ortega VE, Hoffman EA, Kim V, Drummond MB, Bowler RP, Curtis JL, Cooper CB, Tashkin DP, Barjaktarevic IZ. PMID: 34767825; PMCID: PMC9005864.
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    45. Defining Resilience to Smoking-related Lung Disease: A Modified Delphi Approach from SPIROMICS. Ann Am Thorac Soc. 2021 11; 18(11):1822-1831. Oh AL, Mularski RA, Barjaktarevic I, Barr RG, Bowler RP, Comellas AP, Cooper CB, Criner GJ, Han MK, Hansel NN, Hoffman EA, Kanner RE, Krishnan JA, Paine R, Parekh TM, Peters SP, Christenson SA, Woodruff PG, SPIROMICS Smoking Resilience Group. PMID: 33631079; PMCID: PMC8641833.
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    46. Objectively Measured Physical Activity in Patients with COPD: Recommendations from an International Task Force on Physical Activity. Chronic Obstr Pulm Dis. 2021 Oct 28; 8(4):528-550. Demeyer H, Mohan D, Burtin C, Vaes AW, Heasley M, Bowler RP, Casaburi R, Cooper CB, Corriol-Rohou S, Frei A, Hamilton A, Hopkinson NS, Karlsson N, Man WD, Moy ML, Pitta F, Polkey MI, Puhan M, Rennard SI, Rochester CL, Rossiter HB, Sciurba F, Singh S, Tal-Singer R, Vogiatzis I, Watz H, Lummel RV, Wyatt J, Merrill DD, Spruit MA, Garcia-Aymerich J, Troosters T, Chronic Lung Disease Biomarker and Clinical Outcome Assessment Qualification Consortium Task Force o. PMID: 34433239; PMCID: PMC8686852.
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    47. A molecular design approach towards elastic and multifunctional polymer electronics. Nat Commun. 2021 Sep 29; 12(1):5701. Zheng Y, Yu Z, Zhang S, Kong X, Michaels W, Wang W, Chen G, Liu D, Lai JC, Prine N, Zhang W, Nikzad S, Cooper CB, Zhong D, Mun J, Zhang Z, Kang J, Tok JB, McCulloch I, Qin J, Gu X, Bao Z. PMID: 34588448; PMCID: PMC8481247.
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    48. High Energy Density Shape Memory Polymers Using Strain-Induced Supramolecular Nanostructures. ACS Cent Sci. 2021 Oct 27; 7(10):1657-1667. Cooper CB, Nikzad S, Yan H, Ochiai Y, Lai JC, Yu Z, Chen G, Kang J, Bao Z. PMID: 34729409; PMCID: PMC8554838.
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    49. Racial Segregation and Respiratory Outcomes among Urban Black Residents with and at Risk of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2021 09 01; 204(5):536-545. Woo H, Brigham EP, Allbright K, Ejike C, Galiatsatos P, Jones MR, Oates GR, Krishnan JA, Cooper CB, Kanner RE, Bowler RP, Hoffman EA, Comellas AP, Criner G, Barr RG, Martinez FJ, Han M, Ortega VE, Parekh TM, Christenson S, Belz D, Raju S, Gassett A, Paulin LM, Putcha N, Kaufman JD, Hansel NN. PMID: 33971109; PMCID: PMC8491265.
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    50. The Tuberculosis Drug Accelerator at year 10: what have we learned? Nat Med. 2021 08; 27(8):1333-1337. Aldridge BB, Barros-Aguirre D, Barry CE, Bates RH, Berthel SJ, Boshoff HI, Chibale K, Chu XJ, Cooper CB, Dartois V, Duncan K, Fotouhi N, Gusovsky F, Hipskind PA, Kempf DJ, Lelièvre J, Lenaerts AJ, McNamara CW, Mizrahi V, Nathan C, Olsen DB, Parish T, Petrassi HM, Pym A, Rhee KY, Robertson GT, Rock JM, Rubin EJ, Russell B, Russell DG, Sacchettini JC, Schnappinger D, Schrimpf M, Upton AM, Warner P, Wyatt PG, Yuan Y. PMID: 34226736; PMCID: PMC10478072.
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    51. Polycythemia is Associated with Lower Incidence of Severe COPD Exacerbations in the SPIROMICS Study. Chronic Obstr Pulm Dis. 2021 Jul 28; 8(3):326-335. Fawzy A, Woo H, Balasubramanian A, Barjaktarevic I, Barr RG, Bowler RP, Comellas AP, Cooper CB, Couper D, Criner GJ, Dransfield MT, Han MK, Hoffman EA, Kanner RE, Krishnan JA, Martinez FJ, McCormack M, Paine Iii R, Peters S, Wise R, Woodruff PG, Hansel NN, Putcha N. PMID: 34197703; PMCID: PMC8428597.
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    52. Objectively Measured Physical Activity as a COPD Clinical Trial Outcome. Chest. 2021 12; 160(6):2080-2100. Burtin C, Mohan D, Troosters T, Watz H, Hopkinson NS, Garcia-Aymerich J, Moy ML, Vogiatzis I, Rossiter HB, Singh S, Merrill DD, Hamilton A, Rennard SI, Fageras M, Petruzzelli S, Tal-Singer R, Tomaszewski E, Corriol-Rohou S, Rochester CL, Sciurba FC, Casaburi R, Man WD, Van Lummel RC, Cooper CB, Demeyer H, Spruit MA, Vaes A, CBQC Task Force on Physical Activity. PMID: 34217679.
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    53. Response. Med Sci Sports Exerc. 2021 06 01; 53(6):1316. Sirichana W, Neufeld EV, Wang X, Hu SB, Dolezal BA, Cooper CB. PMID: 33986233.
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    54. Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Int J Chron Obstruct Pulmon Dis. 2021; 16:1477-1496. Zou C, Li F, Choi J, Haghighi B, Choi S, Rajaraman PK, Comellas AP, Newell JD, Lee CH, Barr RG, Bleecker E, Cooper CB, Couper D, Han M, Hansel NN, Kanner RE, Kazerooni EA, Kleerup EC, Martinez FJ, O'Neal W, Paine R, Rennard SI, Smith BM, Woodruff PG, Hoffman EA, Lin CL. PMID: 34103907; PMCID: PMC8178702.
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    55. Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2021 11; 9(11):1241-1254. Radicioni G, Ceppe A, Ford AA, Alexis NE, Barr RG, Bleecker ER, Christenson SA, Cooper CB, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kanner RE, Martinez FJ, Ozkan E, Paine R, Woodruff PG, O'Neal WK, Boucher RC, Kesimer M. PMID: 34058148; PMCID: PMC8570975.
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    56. Age-Dependent Associations Between 25-Hydroxy Vitamin D Levels and COPD Symptoms: Analysis of SPIROMICS. Chronic Obstr Pulm Dis. 2021 Apr 27; 8(2):277-291. Burkes RM, Couper DJ, Barjaktarevic IZ, Cooper CB, Labaki WW, Han MK, Woodruff PG, Lazarus SC, Parekh TM, Paine R, Comellas AP, Bowler RP, Loehr LR, Putcha N, Wise RA, Brown TT, Drummond MB. PMID: 33829714; PMCID: PMC8237982.
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    57. Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. Genome Med. 2021 04 21; 13(1):66. Kasela S, Ortega VE, Martorella M, Garudadri S, Nguyen J, Ampleford E, Pasanen A, Nerella S, Buschur KL, Barjaktarevic IZ, Barr RG, Bleecker ER, Bowler RP, Comellas AP, Cooper CB, Couper DJ, Criner GJ, Curtis JL, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Krishnan JA, Martinez FJ, McDonald MN, Meyers DA, Paine R, Peters SP, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Levy BD, Li X, Moore WC, Wenzel SE, Zein J, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS), NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Langelier C, Woodruff PG, Lappalainen T, Christenson SA. PMID: 33883027; PMCID: PMC8059115.
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    58. Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers. Am J Respir Crit Care Med. 2021 04 15; 203(8):957-968. Dunican EM, Elicker BM, Henry T, Gierada DS, Schiebler ML, Anderson W, Barjaktarevic I, Barr RG, Bleecker ER, Boucher RC, Bowler R, Christenson SA, Comellas A, Cooper CB, Couper D, Criner GJ, Dransfield M, Doerschuk CM, Drummond MB, Hansel NN, Han MK, Hastie AT, Hoffman EA, Krishnan JA, Lazarus SC, Martinez FJ, McCulloch CE, O'Neal WK, Ortega VE, Paine R, Peters S, Schroeder JD, Woodruff PG, Fahy JV. PMID: 33180550; PMCID: PMC8048745.
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    59. Contribution of Individual and Neighborhood Factors to Racial Disparities in Respiratory Outcomes. Am J Respir Crit Care Med. 2021 04 15; 203(8):987-997. Ejike CO, Woo H, Galiatsatos P, Paulin LM, Krishnan JA, Cooper CB, Couper DJ, Kanner RE, Bowler RP, Hoffman EA, Comellas AP, Criner GJ, Barr RG, Martinez FJ, Han MK, Martinez CH, Ortega VE, Parekh TM, Christenson SA, Thakur N, Baugh A, Belz DC, Raju S, Gassett AJ, Kaufman JD, Putcha N, Hansel NN. PMID: 33007162; PMCID: PMC8048743.
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    60. The influence of social support on COPD outcomes mediated by depression. PLoS One. 2021; 16(3):e0245478. Turnier L, Eakin M, Woo H, Dransfield M, Parekh T, Krishnan JA, Kanner R, Cooper CB, Woodruff PG, Wise R, Han MK, Romero K, Paulin LM, Peters S, Drummond B, Bleecker ER, Bowler R, Comellas AP, Couper D, Paine R, Martinez F, Barr G, Putcha N, Hansel NN. PMID: 33730034; PMCID: PMC7968645.
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    61. Latent traits of lung tissue patterns in former smokers derived by dual channel deep learning in computed tomography images. Sci Rep. 2021 03 01; 11(1):4916. Li F, Choi J, Zou C, Newell JD, Comellas AP, Lee CH, Ko H, Barr RG, Bleecker ER, Cooper CB, Abtin F, Barjaktarevic I, Couper D, Han M, Hansel NN, Kanner RE, Paine R, Kazerooni EA, Martinez FJ, O'Neal W, Rennard SI, Smith BM, Woodruff PG, Hoffman EA, Lin CL. PMID: 33649381; PMCID: PMC7921389.
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    62. Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort. NPJ Biofilms Microbiomes. 2021 02 05; 7(1):14. Opron K, Begley LA, Erb-Downward JR, Freeman C, Madapoosi S, Alexis NE, Barjaktarevic I, Graham Barr R, Bleecker ER, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper DJ, Doerschuk CM, Dransfield MT, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kaner RJ, Krishnan J, O'Neal WK, Ortega VE, Paine R, Peters SP, Michael Wells J, Woodruff PG, Martinez FJ, Curtis JL, Huffnagle GB, Huang YJ. PMID: 33547327; PMCID: PMC7865064.
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    63. Ratio of FEV1/Slow Vital Capacity of < 0.7 Is Associated With Clinical, Functional, and Radiologic Features of Obstructive Lung Disease in Smokers With Preserved Lung Function. Chest. 2021 07; 160(1):94-103. Fortis S, Comellas AP, Bhatt SP, Hoffman EA, Han MK, Bhakta NR, Paine R, Ronish B, Kanner RE, Dransfield M, Hoesterey D, Buhr RG, Barr RG, Dolezal B, Ortega VE, Drummond MB, Arjomandi M, Kaner RJ, Kim V, Curtis JL, Bowler RP, Martinez F, Labaki WW, Cooper CB, O'Neal WK, Criner G, Hansel NN, Krishnan JA, Woodruff P, Couper D, Tashkin D, Barjaktarevic I. PMID: 33539837; PMCID: PMC8295909.
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    64. Novel Linker Variants of Antileishmanial/Antitubercular 7-Substituted 2-Nitroimidazooxazines Offer Enhanced Solubility. ACS Med Chem Lett. 2021 Feb 11; 12(2):275-281. Thompson AM, O'Connor PD, Yardley V, Maes L, Launay D, Braillard S, Chatelain E, Wan B, Franzblau SG, Ma Z, Cooper CB, Denny WA. PMID: 33603975; PMCID: PMC7883471.
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    65. Modeling residential indoor concentrations of PM2.5 , NO2 , NOx , and secondhand smoke in the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) Air study. Indoor Air. 2021 05; 31(3):702-716. Zusman M, Gassett AJ, Kirwa K, Barr RG, Cooper CB, Han MK, Kanner RE, Koehler K, Ortega VE, Paine Rd R, Paulin L, Pirozzi C, Rule A, Hansel NN, Kaufman JD. PMID: 33037695; PMCID: PMC8202242.
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    66. Reference Values for Chronotropic Index from 1280 Incremental Cycle Ergometry Tests. Med Sci Sports Exerc. 2020 12; 52(12):2515-2521. Sirichana W, Neufeld EV, Wang X, Hu SB, Dolezal BA, Cooper CB. PMID: 32496367.
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    67. Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects. Sci Rep. 2020 11 18; 10(1):20133. Kim V, Jeong S, Zhao H, Kesimer M, Boucher RC, Wells JM, Christenson SA, Han MK, Dransfield M, Paine R, Cooper CB, Barjaktarevic I, Bowler R, Curtis JL, Kaner RJ, O'Beirne SL, O'Neal WK, Rennard SI, Martinez FJ, Woodruff PG. PMID: 33208859; PMCID: PMC7674445.
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    68. Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort. Int J Chron Obstruct Pulmon Dis. 2020; 15:2467-2476. Stott-Miller M, Müllerová H, Miller B, Tabberer M, El Baou C, Keeley T, Martinez FJ, Han M, Dransfield M, Hansel NN, Cooper CB, Woodruff P, Ortega VE, Comellas AP, Paine Iii R, Kanner RE, Anderson W, Drummond MB, Kim V, Tal-Singer R, Lazaar AL. PMID: 33116463; PMCID: PMC7568676.
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    69. Heteroaryl ether analogues of an antileishmanial 7-substituted 2-nitroimidazooxazine lead afford attenuated hERG risk: In vitro and in vivo appraisal. Eur J Med Chem. 2021 Jan 01; 209:112914. Thompson AM, O'Connor PD, Marshall AJ, Yardley V, Maes L, Gupta S, Launay D, Braillard S, Chatelain E, Wan B, Franzblau SG, Ma Z, Cooper CB, Denny WA. PMID: 33268145.
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    70. Plasma Cathelicidin is Independently Associated with Reduced Lung Function in COPD: Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Chronic Obstr Pulm Dis. 2020 Oct; 7(4):370-381. Burkes RM, Ceppe AS, Couper DJ, Comellas AP, Wells JM, Peters SP, Criner GJ, Kanner RE, Paine R, Christenson SA, Cooper CB, Barjaktarevic IZ, Krishnan JA, Labaki WW, Han MK, Curtis JL, Hansel NN, Wise RA, Drummond MB, SPIROMICS collaborators. PMID: 33108110; PMCID: PMC7883905.
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    71. Synthesis and structure-activity relationships for tetrahydroisoquinoline-based inhibitors of Mycobacterium tuberculosis. Bioorg Med Chem. 2020 11 15; 28(22):115784. Lu GL, Tong AST, Conole D, Sutherland HS, Choi PJ, Franzblau SG, Upton AM, Lotlikar MU, Cooper CB, Denny WA, Palmer BD. PMID: 33007562; PMCID: PMC7721589.
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    72. Multivalent Assembly of Flexible Polymer Chains into Supramolecular Nanofibers. J Am Chem Soc. 2020 09 30; 142(39):16814-16824. Cooper CB, Kang J, Yin Y, Yu Z, Wu HC, Nikzad S, Ochiai Y, Yan H, Cai W, Bao Z. PMID: 32901473.
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    73. Remote Patient Monitoring for the Detection of COPD Exacerbations. Int J Chron Obstruct Pulmon Dis. 2020; 15:2005-2013. Cooper CB, Sirichana W, Arnold MT, Neufeld EV, Taylor M, Wang X, Dolezal BA. PMID: 33061338; PMCID: PMC7519812.
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    74. Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease: Highly Effective but Often Overlooked. Tuberc Respir Dis (Seoul). 2020 Oct; 83(4):257-267. Arnold MT, Dolezal BA, Cooper CB. PMID: 32773722; PMCID: PMC7515680.
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    75. Novel Respiratory Disability Score Predicts COPD Exacerbations and Mortality in the SPIROMICS Cohort. Int J Chron Obstruct Pulmon Dis. 2020; 15:1887-1898. Cooper CB, Paine R, Curtis JL, Kanner RE, Martinez CH, Meldrum CA, Bowler R, O'Neal W, Hoffman EA, Couper D, Quibrera M, Criner G, Dransfield MT, Han MK, Hansel NN, Krishnan JA, Lazarus SC, Peters SP, Barr RG, Martinez FJ, Woodruff PG, SPIROMICS investigators. PMID: 32821092; PMCID: PMC7417644.
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    76. Preserving nanoscale features in polymers during laser induced graphene formation using sequential infiltration synthesis. Nat Commun. 2020 Jul 20; 11(1):3636. Bergsman DS, Getachew BA, Cooper CB, Grossman JC. PMID: 32686666; PMCID: PMC7371709.
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    77. Increased airway iron parameters and risk for exacerbation in COPD: an analysis from SPIROMICS. Sci Rep. 2020 06 29; 10(1):10562. Zhang WZ, Oromendia C, Kikkers SA, Butler JJ, O'Beirne S, Kim K, O'Neal WK, Freeman CM, Christenson SA, Peters SP, Wells JM, Doerschuk C, Putcha N, Barjaktarevic I, Woodruff PG, Cooper CB, Bowler RP, Comellas AP, Criner GJ, Paine R, Hansel NN, Han MK, Crystal RG, Kaner RJ, Ballman KV, Curtis JL, Martinez FJ, Cloonan SM. PMID: 32601308; PMCID: PMC7324559.
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    78. Clinical Phenotypes of Atopy and Asthma in COPD: A Meta-analysis of SPIROMICS and COPDGene. Chest. 2020 12; 158(6):2333-2345. Putcha N, Fawzy A, Matsui EC, Liu MC, Bowler RP, Woodruff PG, O'Neal WK, Comellas AP, Han MK, Dransfield MT, Wells JM, Lugogo N, Gao L, Talbot CC, Hoffman EA, Cooper CB, Paulin LM, Kanner RE, Criner G, Ortega VE, Barr RG, Krishnan JA, Martinez FJ, Drummond MB, Wise RA, Diette GB, Hersh CP, Hansel NN. PMID: 32450244; PMCID: PMC7768932.
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    79. Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria. Molecules. 2020 May 22; 25(10). Zhuang Z, Wan D, Ding J, He S, Zhang Q, Wang X, Yuan Y, Lu Y, Ding CZ, Lynch AS, Upton AM, Cooper CB, Denny WA, Ma Z. PMID: 32456032; PMCID: PMC7288012.
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    80. Transition from Restrictive to Obstructive Lung Function Impairment During Treatment and Follow-Up of Active Tuberculosis. Int J Chron Obstruct Pulmon Dis. 2020; 15:1039-1047. Allwood BW, Maasdorp E, Kim GJ, Cooper CB, Goldin J, van Zyl-Smit RN, Bateman ED, Dawson R. PMID: 32494129; PMCID: PMC7227812.
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    81. The Association Between Neighborhood Socioeconomic Disadvantage and Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis. 2020; 15:981-993. Galiatsatos P, Woo H, Paulin LM, Kind A, Putcha N, Gassett AJ, Cooper CB, Dransfield MT, Parekh TM, Oates GR, Barr RG, Comellas AP, Han MK, Peters SP, Krishnan JA, Labaki WW, McCormack MC, Kaufman JD, Hansel NN. PMID: 32440110; PMCID: PMC7211318.
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    82. Synthetic approaches towards bedaquiline and its derivatives. Bioorg Med Chem Lett. 2020 06 15; 30(12):127172. Calvert MB, Furkert DP, Cooper CB, Brimble MA. PMID: 32291133.
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    83. Synthetic Studies to Help Elucidate the Metabolism of the Preclinical Candidate TBAJ-876-A Less Toxic and More Potent Analogue of Bedaquiline. Molecules. 2020 Mar 20; 25(6). Choi PJ, Conole D, Sutherland HS, Blaser A, Tong AST, Cooper CB, Upton AM, Palmer BD, Denny WA. PMID: 32245020; PMCID: PMC7144385.
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    84. Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort. JCI Insight. 2020 02 13; 5(3). Zhang WZ, Rice MC, Hoffman KL, Oromendia C, Barjaktarevic IZ, Wells JM, Hastie AT, Labaki WW, Cooper CB, Comellas AP, Criner GJ, Krishnan JA, Paine R, Hansel NN, Bowler RP, Barr RG, Peters SP, Woodruff PG, Curtis JL, Han MK, Ballman KV, Martinez FJ, Choi AM, Nakahira K, Cloonan SM, Choi ME, SPIROMICS Investigators. PMID: 31895696; PMCID: PMC7098791.
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    85. TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug's Uncoupler Activity. Antimicrob Agents Chemother. 2020 01 27; 64(2). Sarathy JP, Ragunathan P, Cooper CB, Upton AM, Grüber G, Dick T. PMID: 31712198; PMCID: PMC6985740.
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    86. Erratum: Structural and Functional Features on Quantitative Chest Computed Tomography in the Korean Asian versus the White American Healthy Non-Smokers. Korean J Radiol. 2020 Jan; 21(1):117. Cho HB, Chae KJ, Jin GY, Choi J, Lin CL, Hoffman EA, Wenzel SE, Castro M, Fain SB, Jarjour NN, Schiebler ML, Barr RG, Hansel N, Cooper CB, Kleerup EC, Han MK, Woodruff PG, Kanner RE, Bleecker ER, Peters SP, Moore WC, Lee CH, Choi S, National Heart, Lung and Blood Institute's SubPopulations and InteRmediate Outcome Measures In COPD . PMID: 31920035; PMCID: PMC6960314.
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    87. Association of Long-term Ambient Ozone Exposure With Respiratory Morbidity in Smokers. JAMA Intern Med. 2020 01 01; 180(1):106-115. Paulin LM, Gassett AJ, Alexis NE, Kirwa K, Kanner RE, Peters S, Krishnan JA, Paine R, Dransfield M, Woodruff PG, Cooper CB, Barr RG, Comellas AP, Pirozzi CS, Han M, Hoffman EA, Martinez FJ, Woo H, Peng RD, Fawzy A, Putcha N, Breysse PN, Kaufman JD, Hansel NN, for SPIROMICS investigators. PMID: 31816012; PMCID: PMC6902160.
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    88. Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis. Int J Chron Obstruct Pulmon Dis. 2019; 14:2927-2938. Barjaktarevic IZ, Buhr RG, Wang X, Hu S, Couper D, Anderson W, Kanner RE, Paine Iii R, Bhatt SP, Bhakta NR, Arjomandi M, Kaner RJ, Pirozzi CS, Curtis JL, O'Neal WK, Woodruff PG, Han MK, Martinez FJ, Hansel N, Wells JM, Ortega VE, Hoffman EA, Doerschuk CM, Kim V, Dransfield MT, Drummond MB, Bowler R, Criner G, Christenson SA, Ronish B, Peters SP, Krishnan JA, Tashkin DP, Cooper CB, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS). PMID: 31908441; PMCID: PMC6930016.
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    89. Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology. Bioorg Med Chem. 2020 01 01; 28(1):115213. Sutherland HS, Tong AST, Choi PJ, Blaser A, Franzblau SG, Cooper CB, Upton AM, Lotlikar M, Denny WA, Palmer BD. PMID: 31810890.
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    90. Statistical Process Control Improves The Feasibility Of Remote Physiological Monitoring In Patients With Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis. 2019; 14:2485-2496. Cooper CB, Sirichana W, Neufeld EV, Taylor M, Wang X, Dolezal BA. PMID: 32009781; PMCID: PMC6859075.
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    91. Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS. Eur Respir J. 2019 10; 54(4). Arjomandi M, Zeng S, Barjaktarevic I, Barr RG, Bleecker ER, Bowler RP, Buhr RG, Criner GJ, Comellas AP, Cooper CB, Couper DJ, Curtis JL, Dransfield MT, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Kanner RE, Krishnan JA, Paine R, Peters SP, Rennard SI, Woodruff PG, SPIROMICS Investigators. PMID: 31439683; PMCID: PMC7089627.
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    92. TBAJ-876 Retains Bedaquiline's Activity against Subunits c and ε of Mycobacterium tuberculosis F-ATP Synthase. Antimicrob Agents Chemother. 2019 10; 63(10). Sarathy JP, Ragunathan P, Shin J, Cooper CB, Upton AM, Grüber G, Dick T. PMID: 31358589; PMCID: PMC6761534.
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    93. Spirometric indices of early airflow impairment in individuals at risk of developing COPD: Spirometry beyond FEV1/FVC. Respir Med. 2019 09; 156:58-68. Hoesterey D, Das N, Janssens W, Buhr RG, Martinez FJ, Cooper CB, Tashkin DP, Barjaktarevic I. PMID: 31437649; PMCID: PMC6768077.
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    94. Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study. Sci Rep. 2019 08 06; 9(1):11367. Labaki WW, Gu T, Murray S, Curtis JL, Yeomans L, Bowler RP, Barr RG, Comellas AP, Hansel NN, Cooper CB, Barjaktarevic I, Kanner RE, Paine R, McDonald MN, Krishnan JA, Peters SP, Woodruff PG, O'Neal WK, Diao W, He B, Martinez FJ, Standiford TJ, Stringer KA, Han MK. PMID: 31388056; PMCID: PMC6684630.
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    95. Behavioral Modification Enhances the Benefits from Structured Aerobic and Resistance Training. Sports Med Int Open. 2019 Apr; 3(2):E48-E57. Dolezal BA, Boland DM, Neufeld EV, Martin JL, Cooper CB. PMID: 31312715; PMCID: PMC6629998.
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    96. Imaging-based clusters in former smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and intermediate outcome measures in COPD study (SPIROMICS). Respir Res. 2019 Jul 15; 20(1):153. Haghighi B, Choi S, Choi J, Hoffman EA, Comellas AP, Newell JD, Lee CH, Barr RG, Bleecker E, Cooper CB, Couper D, Han ML, Hansel NN, Kanner RE, Kazerooni EA, Kleerup EAC, Martinez FJ, O'Neal W, Paine R, Rennard SI, Smith BM, Woodruff PG, Lin CL. PMID: 31307479; PMCID: PMC6631615.
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    97. Structural and Functional Features on Quantitative Chest Computed Tomography in the Korean Asian versus the White American Healthy Non-Smokers. Korean J Radiol. 2019 07; 20(7):1236-1245. Cho HB, Chae KJ, Jin GY, Choi J, Lin CL, Hoffman EA, Wenzel SE, Castro M, Fain SB, Jarjour NN, Schiebler ML, Barr RG, Hansel N, Cooper CB, Kleerup EC, Han MK, Woodruff PG, Kanner RE, Bleecker ER, Peters SP, Moore WC, Lee CH, Choi S, National Heart, Lung and Blood Institute's SubPopulations and InteRmediate Outcome Measures In COPD . PMID: 31270987; PMCID: PMC6609438.
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    98. Advancing the Therapeutic Potential of Indoleamides for Tuberculosis. Antimicrob Agents Chemother. 2019 07; 63(7). Lun S, Tasneen R, Chaira T, Stec J, Onajole OK, Yang TJ, Cooper CB, Mdluli K, Converse PJ, Nuermberger EL, Raj VS, Kozikowski A, Bishai WR. PMID: 31010860; PMCID: PMC6591635.
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    99. Patient characteristics and outcomes of a home mechanical ventilation program in a developing country. Lung India. 2019 May-Jun; 36(3):207-211. Saiphoklang N, Kanitsap A, Ruchiwit P, Pirompanich P, Sricharoenchai T, Cooper CB. PMID: 31031340; PMCID: PMC6503720.
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    100. Cosensitization in Dye-Sensitized Solar Cells. Chem Rev. 2019 Jun 26; 119(12):7279-7327. Cole JM, Pepe G, Al Bahri OK, Cooper CB. PMID: 31013076.
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    101. Toughening stretchable fibers via serial fracturing of a metallic core. Sci Adv. 2019 Feb; 5(2):eaat4600. Cooper CB, Joshipura ID, Parekh DP, Norkett J, Mailen R, Miller VM, Genzer J, Dickey MD. PMID: 30801003; PMCID: PMC6386561.
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    102. Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline. Bioorg Med Chem. 2019 04 01; 27(7):1283-1291. Blaser A, Sutherland HS, Tong AST, Choi PJ, Conole D, Franzblau SG, Cooper CB, Upton AM, Lotlikar M, Denny WA, Palmer BD. PMID: 30792104; PMCID: PMC6467542.
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    103. 3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel. Bioorg Med Chem. 2019 04 01; 27(7):1292-1307. Sutherland HS, Tong AST, Choi PJ, Blaser A, Conole D, Franzblau SG, Lotlikar MU, Cooper CB, Upton AM, Denny WA, Palmer BD. PMID: 30803745; PMCID: PMC6467547.
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    104. Alignment of Inhaled Chronic Obstructive Pulmonary Disease Therapies with Published Strategies. Analysis of the Global Initiative for Chronic Obstructive Lung Disease Recommendations in SPIROMICS. Ann Am Thorac Soc. 2019 02; 16(2):200-208. Ghosh S, Anderson WH, Putcha N, Han MK, Curtis JL, Criner GJ, Dransfield MT, Barr RG, Krishnan JA, Lazarus SC, Cooper CB, Paine R, Peters SP, Hansel NN, Martinez FJ, Drummond MB, Current and former investigators of the SPIROMICS sites and reading centers. PMID: 30216731; PMCID: PMC6376942.
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    105. Systemic Markers of Inflammation in Smokers With Symptoms Despite Preserved Spirometry in SPIROMICS. Chest. 2019 05; 155(5):908-917. Garudadri S, Woodruff PG, Han MK, Curtis JL, Barr RG, Bleecker ER, Bowler RP, Comellas A, Cooper CB, Criner G, Dransfield MT, Hansel NN, Paine R, Krishnan JA, Peters SP, Hastie AT, Martinez FJ, O'Neal WK, Couper DJ, Alexis NE, Christenson SA. PMID: 30684474; PMCID: PMC6533449.
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    106. Heart Rate Acquisition and Threshold-Based Training Increases Oxygen Uptake at Metabolic Threshold in Triathletes: A Pilot Study. Int J Exerc Sci. 2019; 12(2):144-154. Neufeld EV, Wadowski J, Boland DM, Dolezal BA, Cooper CB. PMID: 30761193; PMCID: PMC6355121.
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    107. Aspirin Use and Respiratory Morbidity in COPD: A Propensity Score-Matched Analysis in Subpopulations and Intermediate Outcome Measures in COPD Study. Chest. 2019 03; 155(3):519-527. Fawzy A, Putcha N, Aaron CP, Bowler RP, Comellas AP, Cooper CB, Dransfield MT, Han MK, Hoffman EA, Kanner RE, Krishnan JA, Labaki WW, Paine R, Paulin LM, Peters SP, Wise R, Barr RG, Hansel NN, SPIROMICS Investigators. PMID: 30593776; PMCID: PMC6414789.
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    108. Occupational Exposures and Computed Tomographic Imaging Characteristics in the SPIROMICS Cohort. Ann Am Thorac Soc. 2018 12; 15(12):1411-1419. Paulin LM, Smith BM, Koch A, Han M, Hoffman EA, Martinez C, Ejike C, Blanc PD, Rous J, Barr RG, Peters SP, Paine R, Pirozzi C, Cooper CB, Dransfield MT, Comellas AP, Kanner RE, Drummond MB, Putcha N, Hansel NN. PMID: 30339479; PMCID: PMC6322018.
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    109. New Spirometry Indices for Detecting Mild Airflow Obstruction. Sci Rep. 2018 11 30; 8(1):17484. Bhatt SP, Bhakta NR, Wilson CG, Cooper CB, Barjaktarevic I, Bodduluri S, Kim YI, Eberlein M, Woodruff PG, Sciurba FC, Castaldi PJ, Han MK, Dransfield MT, Nakhmani A. PMID: 30504791; PMCID: PMC6269456.
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    110. Heterogeneous burden of lung disease in smokers with borderline airflow obstruction. Respir Res. 2018 Nov 20; 19(1):223. Pirozzi CS, Gu T, Quibrera PM, Carretta EE, Han MK, Murray S, Cooper CB, Tashkin DP, Kleerup EC, Barjaktarevic I, Hoffman EA, Martinez CH, Christenson SA, Hansel NN, Graham Barr R, Bleecker ER, Ortega VE, Martinez FJ, Kanner RE, Paine R, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS). PMID: 30454050; PMCID: PMC6245799.
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    111. Bronchodilator responsiveness or reversibility in asthma and COPD - a need for clarity. Int J Chron Obstruct Pulmon Dis. 2018; 13:3511-3513. Barjaktarevic I, Kaner R, Buhr RG, Cooper CB. PMID: 30498341; PMCID: PMC6207394.
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    112. Sleep deprivation and obesity in adults: a brief narrative review. BMJ Open Sport Exerc Med. 2018; 4(1):e000392. Cooper CB, Neufeld EV, Dolezal BA, Martin JL. PMID: 30364557; PMCID: PMC6196958.
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    113. Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Respir Res. 2018 Sep 18; 19(1):178. Haghighi B, Choi S, Choi J, Hoffman EA, Comellas AP, Newell JD, Graham Barr R, Bleecker E, Cooper CB, Couper D, Han ML, Hansel NN, Kanner RE, Kazerooni EA, Kleerup EAC, Martinez FJ, O'Neal W, Rennard SI, Woodruff PG, Lin CL. PMID: 30227877; PMCID: PMC6145340.
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    114. Genome-wide association study of lung function and clinical implication in heavy smokers. BMC Med Genet. 2018 08 01; 19(1):134. Li X, Ortega VE, Ampleford EJ, Graham Barr R, Christenson SA, Cooper CB, Couper D, Dransfield MT, Han MLK, Hansel NN, Hoffman EA, Kanner RE, Kleerup EC, Martinez FJ, Paine R, Woodruff PG, Hawkins GA, Bleecker ER, Meyers DA, SPIROMICS Research Group. PMID: 30068317; PMCID: PMC6090900.
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    115. NT-proBNP in stable COPD and future exacerbation risk: Analysis of the SPIROMICS cohort. Respir Med. 2018 07; 140:87-93. Labaki WW, Xia M, Murray S, Curtis JL, Barr RG, Bhatt SP, Bleecker ER, Hansel NN, Cooper CB, Dransfield MT, Wells JM, Hoffman EA, Kanner RE, Paine R, Ortega VE, Peters SP, Krishnan JA, Bowler RP, Couper DJ, Woodruff PG, Martinez FJ, Martinez CH, Han MK. PMID: 29957287; PMCID: PMC6084793.
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    116. Effect of altering breathing frequency on maximum voluntary ventilation in healthy adults. BMC Pulm Med. 2018 May 24; 18(1):89. Neufeld EV, Dolezal BA, Speier W, Cooper CB. PMID: 29793460; PMCID: PMC5968560.
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    117. The Significance of Eosinophilic Inflammation in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 04 01; 197(7):967-968. Cooper CB, Brusselle G, Pascoe SJ, Pavord ID. PMID: 29140724.
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    118. Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis. J Med Chem. 2018 03 22; 61(6):2329-2352. Thompson AM, O'Connor PD, Marshall AJ, Blaser A, Yardley V, Maes L, Gupta S, Launay D, Braillard S, Chatelain E, Wan B, Franzblau SG, Ma Z, Cooper CB, Denny WA. PMID: 29461823; PMCID: PMC5867678.
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    119. Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles. Bioorg Med Chem. 2018 05 01; 26(8):1797-1809. Sutherland HS, Tong AST, Choi PJ, Conole D, Blaser A, Franzblau SG, Cooper CB, Upton AM, Lotlikar MU, Denny WA, Palmer BD. PMID: 29482950; PMCID: PMC5933462.
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    120. Marijuana Use Associations with Pulmonary Symptoms and Function in Tobacco Smokers Enrolled in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Chronic Obstr Pulm Dis. 2018 Jan 24; 5(1):46-56. Morris MA, Jacobson SR, Kinney GL, Tashkin DP, Woodruff PG, Hoffman EA, Kanner RE, Cooper CB, Drummond MB, Barr RG, Oelsner EC, Make BJ, Han MK, Hansel NN, O'Neal WK, Bowler RP. PMID: 29629404; PMCID: PMC5870739.
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    121. Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid. ACS Med Chem Lett. 2017 Dec 14; 8(12):1275-1280. Thompson AM, Bonnet M, Lee HH, Franzblau SG, Wan B, Wong GS, Cooper CB, Denny WA. PMID: 29259747; PMCID: PMC5733301.
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    122. Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017 12; 5(12):956-967. Hastie AT, Martinez FJ, Curtis JL, Doerschuk CM, Hansel NN, Christenson S, Putcha N, Ortega VE, Li X, Barr RG, Carretta EE, Couper DJ, Cooper CB, Hoffman EA, Kanner RE, Kleerup E, O'Neal WK, Paine R, Peters SP, Alexis NE, Woodruff PG, Han MK, Meyers DA, Bleecker ER, SPIROMICS investigators. PMID: 29146301; PMCID: PMC5849066.
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    123. Differentiation of quantitative CT imaging phenotypes in asthma versus COPD. BMJ Open Respir Res. 2017; 4(1):e000252. Choi S, Haghighi B, Choi J, Hoffman EA, Comellas AP, Newell JD, Wenzel SE, Castro M, Fain SB, Jarjour NN, Schiebler ML, Barr RG, Han MK, Bleecker ER, Cooper CB, Couper D, Hansel N, Kanner RE, Kazerooni EA, Kleerup EAC, Martinez FJ, O'Neal WK, Woodruff PG, Lin CL. PMID: 29435345; PMCID: PMC5687530.
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    124. Diagnostic Value of Quantitative Chest CT Scan in a Case of Spontaneous Pneumothorax. Chest. 2017 11; 152(5):e109-e114. Melamed KH, Abtin F, Barjaktarevic I, Cooper CB. PMID: 29126535.
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    125. Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units. Bioorg Med Chem Lett. 2017 12 01; 27(23):5190-5196. Choi PJ, Sutherland HS, Tong AST, Blaser A, Franzblau SG, Cooper CB, Lotlikar MU, Upton AM, Guillemont J, Motte M, Queguiner L, Andries K, Van den Broeck W, Denny WA, Palmer BD. PMID: 29107541; PMCID: PMC5696560.
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    126. Corrigendum to "Interrelationship between Sleep and Exercise: A Systematic Review". Adv Prev Med. 2017; 2017:5979510. Dolezal BA, Neufeld EV, Boland DM, Martin JL, Cooper CB. PMID: 29123925; PMCID: PMC5662799.
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    127. 6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis. ACS Med Chem Lett. 2017 Oct 12; 8(10):1019-1024. Tong AST, Choi PJ, Blaser A, Sutherland HS, Tsang SKY, Guillemont J, Motte M, Cooper CB, Andries K, Van den Broeck W, Franzblau SG, Upton AM, Denny WA, Palmer BD, Conole D. PMID: 29057044; PMCID: PMC5642017.
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    128. Variability in objective and subjective measures affects baseline values in studies of patients with COPD. PLoS One. 2017; 12(9):e0184606. Anderson WH, Ha JW, Couper DJ, O'Neal WK, Barr RG, Bleecker ER, Carretta EE, Cooper CB, Doerschuk CM, Drummond MB, Han MK, Hansel NN, Kim V, Kleerup EC, Martinez FJ, Rennard SI, Tashkin D, Woodruff PG, Paine R, Curtis JL, Kanner RE, SPIROMICS Research Group. PMID: 28934249; PMCID: PMC5608200.
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    129. Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort. J Allergy Clin Immunol. 2018 01; 141(1):429-432. Martinez CH, Li SX, Hirzel AJ, Stolberg VR, Alexis NE, Barr RG, Bleecker ER, Carretta EE, Christenson SA, Cooper CB, Couper DJ, Doerschuk CM, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kaner RJ, Martinez FJ, Meyers DA, O'Neal WK, Paine R, Putcha N, Rennard SI, Woodruff PG, Zeidler M, Curtis JL, Freeman CM, SPIROMICS Investigators. PMID: 28916185; PMCID: PMC5758424.
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    130. Airway Mucin Concentration as a Marker of Chronic Bronchitis. N Engl J Med. 2017 09 07; 377(10):911-922. Kesimer M, Ford AA, Ceppe A, Radicioni G, Cao R, Davis CW, Doerschuk CM, Alexis NE, Anderson WH, Henderson AG, Barr RG, Bleecker ER, Christenson SA, Cooper CB, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kanner RE, Martinez F, Paine R, Woodruff PG, O'Neal WK, Boucher RC. PMID: 28877023; PMCID: PMC5706541.
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    131. A Systematic Method to Detect the Metabolic Threshold from Gas Exchange during Incremental Exercise. J Sports Sci Med. 2017 Sep; 16(3):396-406. Dolezal BA, Storer TW, Neufeld EV, Smooke S, Tseng CH, Cooper CB. PMID: 28912658; PMCID: PMC5592292.
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    132. Cardiopulmonary Exercise Testing and Metabolic Myopathies. Ann Am Thorac Soc. 2017 Jul; 14(Supplement_1):S129-S139. Riley MS, Nicholls DP, Cooper CB. PMID: 28590155.
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    133. Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort. Lancet Respir Med. 2017 08; 5(8):619-626. Han MK, Quibrera PM, Carretta EE, Barr RG, Bleecker ER, Bowler RP, Cooper CB, Comellas A, Couper DJ, Curtis JL, Criner G, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Krishnan JA, Martinez CH, Pirozzi CB, O'Neal WK, Rennard S, Tashkin DP, Wedzicha JA, Woodruff P, Paine R, Martinez FJ, SPIROMICS investigators. PMID: 28668356; PMCID: PMC5558856.
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    134. Design of the Subpopulations and Intermediate Outcome Measures in COPD (SPIROMICS) AIR Study. BMJ Open Respir Res. 2017; 4(1):e000186. Hansel NN, Paulin LM, Gassett AJ, Peng RD, Alexis N, Fan VS, Bleecker E, Bowler R, Comellas AP, Dransfield M, Han MK, Kim V, Krishnan JA, Pirozzi C, Cooper CB, Martinez F, Woodruff PG, Breysse PJ, Barr RG, Kaufman JD. PMID: 28948026; PMCID: PMC5595208.
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    135. 7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis. J Med Chem. 2017 05 25; 60(10):4212-4233. Thompson AM, O'Connor PD, Marshall AJ, Yardley V, Maes L, Gupta S, Launay D, Braillard S, Chatelain E, Franzblau SG, Wan B, Wang Y, Ma Z, Cooper CB, Denny WA. PMID: 28459575; PMCID: PMC7722354.
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    136. Reduced COPD Exacerbation Risk Correlates With Improved FEV1: A Meta-Regression Analysis. Chest. 2017 09; 152(3):494-501. Zider AD, Wang X, Buhr RG, Sirichana W, Barjaktarevic IZ, Cooper CB. PMID: 28483609; PMCID: PMC6026240.
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    137. Respiratory Symptoms Items from the COPD Assessment Test Identify Ever-Smokers with Preserved Lung Function at Higher Risk for Poor Respiratory Outcomes. An Analysis of the Subpopulations and Intermediate Outcome Measures in COPD Study Cohort. Ann Am Thorac Soc. 2017 May; 14(5):636-642. Martinez CH, Murray S, Barr RG, Bleecker E, Bowler RP, Christenson SA, Comellas AP, Cooper CB, Couper D, Criner GJ, Curtis JL, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Kleerup E, Krishnan JA, Lazarus SC, Leidy NK, O'Neal W, Martinez FJ, Paine R, Rennard SI, Tashkin DP, Woodruff PG, Han MK, Subpopulations and Intermediate Outcome Measures in COPD Study Investigators. PMID: 28459622; PMCID: PMC5427740.
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    138. Obstructive pulmonary disease in patients with previous tuberculosis: Pathophysiology of a community-based cohort. S Afr Med J. 2017 Apr 25; 107(5):440-445. Allwood BW, Gillespie R, Galperin-Aizenberg M, Bateman M, Olckers H, Taborda-Barata L, Calligaro GL, Said-Hartley Q, Van Zyl-Smit R, Cooper CB, Van Rikxoort E, Goldin J, Beyers N, Bateman ED. PMID: 28492127.
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    139. Exercise responses in patients with chronically high creatine kinase levels. Muscle Nerve. 2017 08; 56(2):264-270. Cooper CB, Dolezal BA, Neufeld EV, Shieh P, Jenner JR, Riley M. PMID: 27935086.
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    140. Interrelationship between Sleep and Exercise: A Systematic Review. Adv Prev Med. 2017; 2017:1364387. Dolezal BA, Neufeld EV, Boland DM, Martin JL, Cooper CB. PMID: 28458924; PMCID: PMC5385214.
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    141. Age and Small Airway Imaging Abnormalities in Subjects with and without Airflow Obstruction in SPIROMICS. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):464-472. Martinez CH, Diaz AA, Meldrum C, Curtis JL, Cooper CB, Pirozzi C, Kanner RE, Paine R, Woodruff PG, Bleecker ER, Hansel NN, Barr RG, Marchetti N, Criner GJ, Kazerooni EA, Hoffman EA, Ross BD, Galban CJ, Cigolle CT, Martinez FJ, Han MK, SPIROMICS Investigators. PMID: 27564413; PMCID: PMC5378423.
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    142. Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis. J Med Chem. 2017 02 23; 60(4):1379-1399. Tantry SJ, Markad SD, Shinde V, Bhat J, Balakrishnan G, Gupta AK, Ambady A, Raichurkar A, Kedari C, Sharma S, Mudugal NV, Narayan A, Naveen Kumar CN, Nanduri R, Bharath S, Reddy J, Panduga V, Prabhakar KR, Kandaswamy K, Saralaya R, Kaur P, Dinesh N, Guptha S, Rich K, Murray D, Plant H, Preston M, Ashton H, Plant D, Walsh J, Alcock P, Naylor K, Collier M, Whiteaker J, McLaughlin RE, Mallya M, Panda M, Rudrapatna S, Ramachandran V, Shandil R, Sambandamurthy VK, Mdluli K, Cooper CB, Rubin H, Yano T, Iyer P, Narayanan S, Kavanagh S, Mukherjee K, Balasubramanian V, Hosagrahara VP, Solapure S, Ravishankar S, Hameed P S. PMID: 28075132.
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    143. Wrist-worn triaxial accelerometry predicts the energy expenditure of non-vigorous daily physical activities. J Sci Med Sport. 2017 Aug; 20(8):761-765. Sirichana W, Dolezal BA, Neufeld EV, Wang X, Cooper CB. PMID: 28159535.
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    144. Inter- and intra-rater agreement of static posture analysis using a mobile application. J Phys Ther Sci. 2016 Dec; 28(12):3398-3402. Boland DM, Neufeld EV, Ruddell J, Dolezal BA, Cooper CB. PMID: 28174460; PMCID: PMC5276769.
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    145. Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase. Antimicrob Agents Chemother. 2016 10; 60(10):6271-80. Palencia A, Li X, Bu W, Choi W, Ding CZ, Easom EE, Feng L, Hernandez V, Houston P, Liu L, Meewan M, Mohan M, Rock FL, Sexton H, Zhang S, Zhou Y, Wan B, Wang Y, Franzblau SG, Woolhiser L, Gruppo V, Lenaerts AJ, O'Malley T, Parish T, Cooper CB, Waters MG, Ma Z, Ioerger TR, Sacchettini JC, Rullas J, Angulo-Barturen I, Pérez-Herrán E, Mendoza A, Barros D, Cusack S, Plattner JJ, Alley MR. PMID: 27503647; PMCID: PMC5038265.
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    146. Exploratory Study of Heart Rate Variability and Sleep among Emergency Medical Services Shift Workers. Prehosp Emerg Care. 2017 Jan-Feb; 21(1):18-23. Neufeld EV, Carney JJ, Dolezal BA, Boland DM, Cooper CB. PMID: 27487176.
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    147. A controlled statistical study to assess measurement variability as a function of test object position and configuration for automated surveillance in a multicenter longitudinal COPD study (SPIROMICS). Med Phys. 2016 May; 43(5):2598. Guo J, Wang C, Chan KS, Jin D, Saha PK, Sieren JP, Barr RG, Han MK, Kazerooni E, Cooper CB, Couper D, Newell JD, Hoffman EA, SPIROMICS Research Group. PMID: 27147369; PMCID: PMC4851622.
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    148. Reverse fiber type disproportion: A distinct metabolic myopathy. Muscle Nerve. 2016 06; 54(1):86-93. Cooper CB, Dolezal BA, Riley M, Verity MA, Shieh PB. PMID: 26600317.
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    149. Effect of Exercise Training on Striatal Dopamine D2/D3 Receptors in Methamphetamine Users during Behavioral Treatment. Neuropsychopharmacology. 2016 May; 41(6):1629-36. Robertson CL, Ishibashi K, Chudzynski J, Mooney LJ, Rawson RA, Dolezal BA, Cooper CB, Brown AK, Mandelkern MA, London ED. PMID: 26503310; PMCID: PMC4832026.
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    150. Impact of an exercise intervention on methamphetamine use outcomes post-residential treatment care. Drug Alcohol Depend. 2015 Nov 01; 156:21-28. Rawson RA, Chudzynski J, Mooney L, Gonzales R, Ang A, Dickerson D, Penate J, Salem BA, Dolezal B, Cooper CB. PMID: 26371404; PMCID: PMC4633370.
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    151. Supplemental Oxygen Therapy for Patients with Chronic Obstructive Pulmonary Disease. Semin Respir Crit Care Med. 2015 Aug; 36(4):552-66. Barjaktarevic I, Cooper CB. PMID: 26238641.
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    152. Positioning new pharmacotherapies for COPD. Int J Chron Obstruct Pulmon Dis. 2015; 10:1427-42. Barjaktarevic IZ, Arredondo AF, Cooper CB. PMID: 26244017; PMCID: PMC4521666.
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    153. COPD management: need for more consensus - Authors' reply. Lancet Respir Med. 2015 Jul; 3(7):e22-3. Cooper CB, Barjaktarevic I. PMID: 26170080.
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    154. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. Eur Respir Rev. 2015 Jun; 24(136):159-72. Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí AA, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Maltais F, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL, ATS/ERS Task Force for COPD Research. PMID: 26028628; PMCID: PMC9487818.
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    155. Diffusing capacity for carbon monoxide correlates best with tissue volume from quantitative CT scanning analysis. Chest. 2015 Jun; 147(6):1485-1493. Barjaktarevic I, Springmeyer S, Gonzalez X, Sirokman W, Coxson HO, Cooper CB. PMID: 25500912.
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    156. The Impact of Exercise On Depression and Anxiety Symptoms Among Abstinent Methamphetamine-Dependent Individuals in A Residential Treatment Setting. J Subst Abuse Treat. 2015 Oct; 57:36-40. Rawson RA, Chudzynski J, Gonzales R, Mooney L, Dickerson D, Ang A, Dolezal B, Cooper CB. PMID: 25934458; PMCID: PMC4560957.
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    157. A randomised trial of lung sealant versus medical therapy for advanced emphysema. Eur Respir J. 2015 Sep; 46(3):651-62. Come CE, Kramer MR, Dransfield MT, Abu-Hijleh M, Berkowitz D, Bezzi M, Bhatt SP, Boyd MB, Cases E, Chen AC, Cooper CB, Flandes J, Gildea T, Gotfried M, Hogarth DK, Kolandaivelu K, Leeds W, Liesching T, Marchetti N, Marquette C, Mularski RA, Pinto-Plata VM, Pritchett MA, Rafeq S, Rubio ER, Slebos DJ, Stratakos G, Sy A, Tsai LW, Wahidi M, Walsh J, Wells JM, Whitten PE, Yusen R, Zulueta JJ, Criner GJ, Washko GR. PMID: 25837041; PMCID: PMC4826269.
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    158. A new algorithm for the management of COPD. Lancet Respir Med. 2015 Apr; 3(4):266-8. Cooper CB, Barjaktarevic I. PMID: 25890644.
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    159. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. Eur Respir J. 2015 Apr; 45(4):879-905. Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Maltais F, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL, ATS/ERS Task Force for COPD Research. PMID: 25829431.
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    160. Predictors of depression outcomes among abstinent methamphetamine-dependent individuals exposed to an exercise intervention. Am J Addict. 2015 Apr; 24(3):246-251. Haglund M, Ang A, Mooney L, Gonzales R, Chudzynski J, Cooper CB, Dolezal BA, Gitlin M, Rawson RA. PMID: 25907813.
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    161. An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):e4-e27. Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Maltais F, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL, ATS/ERS Task Force for COPD Research. PMID: 25830527.
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    162. The IBV Valve trial: a multicenter, randomized, double-blind trial of endobronchial therapy for severe emphysema. J Bronchology Interv Pulmonol. 2014 Oct; 21(4):288-97. Wood DE, Nader DA, Springmeyer SC, Elstad MR, Coxson HO, Chan A, Rai NS, Mularski RA, Cooper CB, Wise RA, Jones PW, Mehta AC, Gonzalez X, Sterman DH, IBV Valve Trial Research Team. PMID: 25321447.
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    163. A controlled study of community-based exercise training in patients with moderate COPD. BMC Pulm Med. 2014 Aug 04; 14:125. Amin S, Abrazado M, Quinn M, Storer TW, Tseng CH, Cooper CB. PMID: 25088030; PMCID: PMC4124480.
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    164. Effect of supervised, periodized exercise training vs. self-directed training on lean body mass and other fitness variables in health club members. J Strength Cond Res. 2014 Jul; 28(7):1995-2006. Storer TW, Dolezal BA, Berenc MN, Timmins JE, Cooper CB. PMID: 24276303.
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    165. 1,4-azaindole, a potential drug candidate for treatment of tuberculosis. Antimicrob Agents Chemother. 2014 Sep; 58(9):5325-31. Chatterji M, Shandil R, Manjunatha MR, Solapure S, Ramachandran V, Kumar N, Saralaya R, Panduga V, Reddy J, Prabhakar KR, Sharma S, Sadler C, Cooper CB, Mdluli K, Iyer PS, Narayanan S, Shirude PS. PMID: 24957839; PMCID: PMC4135869.
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    166. Lead optimization of 1,4-azaindoles as antimycobacterial agents. J Med Chem. 2014 Jul 10; 57(13):5728-37. Shirude PS, Shandil RK, Manjunatha MR, Sadler C, Panda M, Panduga V, Reddy J, Saralaya R, Nanduri R, Ambady A, Ravishankar S, Sambandamurthy VK, Humnabadkar V, Jena LK, Suresh RS, Srivastava A, Prabhakar KR, Whiteaker J, McLaughlin RE, Sharma S, Cooper CB, Mdluli K, Butler S, Iyer PS, Narayanan S, Chatterji M. PMID: 24874895.
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    167. Exercise training improves heart rate variability after methamphetamine dependency. Med Sci Sports Exerc. 2014 Jun; 46(6):1057-66. Dolezal BA, Chudzynski J, Dickerson D, Mooney L, Rawson RA, Garfinkel A, Cooper CB. PMID: 24162556; PMCID: PMC3999306.
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    168. Deployment of remote advanced electrocardiography for improved cardiovascular risk assessment in career firefighters. Telemed J E Health. 2014 Jul; 20(7):660-3. Dolezal BA, Abrazado M, Batalin MA, Smith D, Cooper CB. PMID: 24796429.
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    169. Synthesis and biological evaluation of novel 2-methoxypyridylamino-substituted riminophenazine derivatives as antituberculosis agents. Molecules. 2014 Apr 09; 19(4):4380-94. Zhang D, Liu Y, Zhang C, Zhang H, Wang B, Xu J, Fu L, Yin D, Cooper CB, Ma Z, Lu Y, Huang H. PMID: 24722591; PMCID: PMC6271099.
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    170. Firefighter health and fitness assessment: a call to action. J Strength Cond Res. 2014 Mar; 28(3):661-71. Storer TW, Dolezal BA, Abrazado ML, Smith DL, Batalin MA, Tseng CH, Cooper CB, PHASER Study Group. PMID: 24566608.
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    171. Evaluation of a wearable physiological status monitor during simulated fire fighting activities. J Occup Environ Hyg. 2014; 11(7):427-33. Smith DL, Haller JM, Dolezal BA, Cooper CB, Fehling PC. PMID: 24433269.
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    172. Use of the HR index to predict maximal oxygen uptake during different exercise protocols. Physiol Rep. 2013 Oct; 1(5):e00124. Haller JM, Fehling PC, Barr DA, Storer TW, Cooper CB, Smith DL. PMID: 24303190; PMCID: PMC3841054.
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    173. Comparing dynamic hyperinflation and associated dyspnea induced by metronome-paced tachypnea versus incremental exercise. COPD. 2014 Feb; 11(1):105-12. Calligaro GL, Raine RI, Bateman ME, Bateman ED, Cooper CB. PMID: 24152211.
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    174. Development of Mycobacterium tuberculosis whole cell screening hits as potential antituberculosis agents. J Med Chem. 2013 Oct 24; 56(20):7755-60. Cooper CB. PMID: 23927683.
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    175. Determinants of dynamic hyperinflation during metronome-paced tachypnea in COPD and normal subjects. Respir Physiol Neurobiol. 2014 Jan 01; 190:76-80. Cooper CB, Calligaro GL, Quinn MM, Eshaghian P, Coskun F, Abrazado M, Bateman ED, Raine RI. PMID: 23994176.
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    176. Treadmill endurance during 2-year treatment with tiotropium in patients with COPD: a randomized trial. Chest. 2013 Aug; 144(2):490-497. Cooper CB, Celli BR, Jardim JR, Wise RA, Legg D, Guo J, Kesten S. PMID: 23558890.
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    177. The effect of precooling on cardiovascular and metabolic strain during incremental exercise. Appl Physiol Nutr Metab. 2013 Sep; 38(9):935-40. Smith DL, Fehling PC, Hultquist EM, Arena L, Lefferts WK, Haller JM, Storer TW, Cooper CB. PMID: 23905658.
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    178. Global Initiative on Obstructive Lung Disease revised: what constitutes a guideline? Am J Respir Crit Care Med. 2013 May 15; 187(10):1035-6. Rabe KF, Cooper CB. PMID: 23675707.
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    179. Eight weeks of exercise training improves fitness measures in methamphetamine-dependent individuals in residential treatment. J Addict Med. 2013 Mar-Apr; 7(2):122-8. Dolezal BA, Chudzynski J, Storer TW, Abrazado M, Penate J, Mooney L, Dickerson D, Rawson RA, Cooper CB. PMID: 23552821; PMCID: PMC3617407.
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    180. Identification of less lipophilic riminophenazine derivatives for the treatment of drug-resistant tuberculosis. J Med Chem. 2012 Oct 11; 55(19):8409-17. Zhang D, Lu Y, Liu K, Liu B, Wang J, Zhang G, Zhang H, Liu Y, Wang B, Zheng M, Fu L, Hou Y, Gong N, Lv Y, Li C, Cooper CB, Upton AM, Yin D, Ma Z, Huang H. PMID: 22931472.
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    181. Firefighter's personal protective equipment and the chronotropic index. Ergonomics. 2012; 55(10):1243-51. Smith DL, Fehling PC, Hultquist EM, Lefferts WK, Barr DA, Storer TW, Cooper CB. PMID: 22849757.
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    182. Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors. J Med Chem. 2012 Jul 12; 55(13):6162-75. Harikrishnan LS, Finlay HJ, Qiao JX, Kamau MG, Jiang J, Wang TC, Li J, Cooper CB, Poss MA, Adam LP, Taylor DS, Chen AY, Yin X, Sleph PG, Yang RZ, Sitkoff DF, Galella MA, Nirschl DS, Van Kirk K, Miller AV, Huang CS, Chang M, Chen XQ, Salvati ME, Wexler RR, Lawrence RM. PMID: 22650305.
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    183. Strategies and challenges involved in the discovery of new chemical entities during early-stage tuberculosis drug discovery. J Infect Dis. 2012 May 15; 205 Suppl 2:S258-64. Coxon GD, Cooper CB, Gillespie SH, McHugh TD. PMID: 22448016.
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    184. Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1). Bioorg Med Chem Lett. 2012 Mar 15; 22(6):2287-90. Harikrishnan LS, Srivastava N, Kayser LE, Nirschl DS, Kumaragurubaran K, Roy A, Gupta A, Karmakar S, Karatt T, Mathur A, Burford NT, Chen J, Kong Y, Cvijic M, Cooper CB, Poss MA, Trainor GL, Wong TW. PMID: 22365758.
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    185. Tiotropium reduces risk of exacerbations irrespective of previous use of inhaled anticholinergics in placebo-controlled clinical trials. Int J Chron Obstruct Pulmon Dis. 2011; 6:269-75. Cooper CB, Anzueto A, Decramer M, Celli B, Tashkin DP, Leimer I, Kesten S. PMID: 21845038; PMCID: PMC3152465.
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    186. Do holes in the lungs beget holes in the bones? Am J Respir Crit Care Med. 2011 Apr 01; 183(7):835-7. Cooper CB. PMID: 21471073.
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    187. Cardiovascular magnetic resonance in patients with pectus excavatum compared with normal controls. J Cardiovasc Magn Reson. 2010 Dec 13; 12:73. Saleh RS, Finn JP, Fenchel M, Moghadam AN, Krishnam M, Abrazado M, Ton A, Habibi R, Fonkalsrud EW, Cooper CB. PMID: 21144053; PMCID: PMC3022801.
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    188. Development and implementation of treadmill exercise testing protocols in COPD. Int J Chron Obstruct Pulmon Dis. 2010 Oct 12; 5:375-85. Cooper CB, Abrazado M, Legg D, Kesten S. PMID: 21103404; PMCID: PMC2981152.
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    189. Treatment of COPD: the sooner the better? Thorax. 2010 Sep; 65(9):837-41. Decramer M, Cooper CB. PMID: 20805184.
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    190. Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial. J Altern Complement Med. 2010 May; 16(5):585-90. Chen S, Li Z, Krochmal R, Abrazado M, Kim W, Cooper CB. PMID: 20804368; PMCID: PMC3110835.
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    191. Exploration of structure-activity relationships at the two C-terminal residues of potent 11mer Glucagon-Like Peptide-1 receptor agonist peptides via parallel synthesis. Peptides. 2010 Jul; 31(7):1353-60. Haque TS, Martinez RL, Lee VG, Riexinger DG, Lei M, Feng M, Koplowitz B, Mapelli C, Cooper CB, Zhang G, Huang C, Ewing WR, Krupinski J. PMID: 20420872.
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    192. An arteriovenous fistula increases exercise capacity in patients with COPD. Chest. 2010 Jul; 138(1):52-8. Faul JL, Galindo J, Posadas-Valay R, Elizondo-Riojas G, Martinez A, Cooper CB. PMID: 20382714.
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    193. Effective inspired oxygen concentration measured via transtracheal and oral gas analysis. Respir Care. 2010 Apr; 55(4):453-9. Markovitz GH, Colthurst J, Storer TW, Cooper CB. PMID: 20406513.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    194. Identification of potent 11mer glucagon-like peptide-1 receptor agonist peptides with novel C-terminal amino acids: Homohomophenylalanine analogs. Peptides. 2010 May; 31(5):950-5. Haque TS, Lee VG, Riexinger D, Lei M, Malmstrom S, Xin L, Han S, Mapelli C, Cooper CB, Zhang G, Ewing WR, Krupinski J. PMID: 20138099.
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    195. Rehabilitation in non-COPD: mechanisms of exercise limitation and pulmonary rehabilitation for patients with pulmonary fibrosis/restrictive lung disease. Chron Respir Dis. 2010; 7(1):47-60. Markovitz GH, Cooper CB. PMID: 19880656.
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    196. Potent biphenyl- and 3-phenyl pyridine-based inhibitors of acetyl-CoA carboxylase. Bioorg Med Chem Lett. 2009 Oct 15; 19(20):5872-6. Haque TS, Liang N, Golla R, Seethala R, Ma Z, Ewing WR, Cooper CB, Pelleymounter MA, Poss MA, Cheng D. PMID: 19740659.
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    197. Desensitization to dyspnea in COPD with specificity for exercise training mode. Int J Chron Obstruct Pulmon Dis. 2009; 4:33-43. Cooper CB. PMID: 19436684; PMCID: PMC2672788.
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    198. Respiratory applications of telemedicine. Thorax. 2009 Mar; 64(3):189-91. Cooper CB. PMID: 19252017.
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    199. Discovery and structure-activity relationships of trisubstituted pyrimidines/pyridines as novel calcium-sensing receptor antagonists. J Med Chem. 2009 Feb 26; 52(4):1204-8. Yang W, Ruan Z, Wang Y, Van Kirk K, Ma Z, Arey BJ, Cooper CB, Seethala R, Feyen JH, Dickson JK. PMID: 19143533.
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    200. Design and synthesis of a G-protein-coupled receptor antagonist library of aryloxyalkanolamines using a polymer-supported acyclic acetal linker. J Comb Chem. 2009 Jan-Feb; 11(1):72-82. Roberge JY, Harikrishnan LS, Kamau MG, Ruan Z, Van Kirk K, Liu Y, Cooper CB, Poss MA, Dickson JK, Gavai AV, Chao ST, Leith LW, Bednarz MS, Mathur A, Kakarla R, Schnur DM, Vaz R, Lawrence RM. PMID: 19086798.
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    201. Airflow obstruction and exercise. Respir Med. 2009 Mar; 103(3):325-34. Cooper CB. PMID: 19071004.
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    202. Venous admixture in COPD: pathophysiology and therapeutic approaches. COPD. 2008 Dec; 5(6):376-81. Cooper CB, Celli B. PMID: 19353352; PMCID: PMC2645850.
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    203. Time course and degree of hyperinflation with metronome-paced tachypnea in COPD patients. COPD. 2008 Oct; 5(5):298-304. Weigt SS, Abrazado M, Kleerup EC, Tashkin DP, Cooper CB. PMID: 18972278.
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    204. COPD as a lung disease with systemic consequences--clinical impact, mechanisms, and potential for early intervention. COPD. 2008 Aug; 5(4):235-56. Decramer M, Rennard S, Troosters T, Mapel DW, Giardino N, Mannino D, Wouters E, Sethi S, Cooper CB. PMID: 18671149.
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    205. Primary care of the patient with chronic obstructive pulmonary disease-part 4: understanding the clinical manifestations of a progressive disease. Am J Med. 2008 Jul; 121(7 Suppl):S33-45. Cooper CB, Dransfield M. PMID: 18558106.
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    206. Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1. Bioorg Med Chem Lett. 2008 Jun 01; 18(11):3168-72. Wang H, Ruan Z, Li JJ, Simpkins LM, Smirk RA, Wu SC, Hutchins RD, Nirschl DS, Van Kirk K, Cooper CB, Sutton JC, Ma Z, Golla R, Seethala R, Salyan ME, Nayeem A, Krystek SR, Sheriff S, Camac DM, Morin PE, Carpenter B, Robl JA, Zahler R, Gordon DA, Hamann LG. PMID: 18485702.
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    207. 2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: optimization via array synthesis. Bioorg Med Chem Lett. 2008 Apr 15; 18(8):2640-4. Harikrishnan LS, Kamau MG, Herpin TF, Morton GC, Liu Y, Cooper CB, Salvati ME, Qiao JX, Wang TC, Adam LP, Taylor DS, Chen AY, Yin X, Seethala R, Peterson TL, Nirschl DS, Miller AV, Weigelt CA, Appiah KK, O'Connell JC, Michael Lawrence R. PMID: 18374566.
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    208. Improvement in self-reported exercise participation with the combination of tiotropium and rehabilitative exercise training in COPD patients. Int J Chron Obstruct Pulmon Dis. 2008; 3(1):127-36. Kesten S, Casaburi R, Kukafka D, Cooper CB. PMID: 18488436; PMCID: PMC2528216.
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    209. The connection between chronic obstructive pulmonary disease symptoms and hyperinflation and its impact on exercise and function. Am J Med. 2006 Oct; 119(10 Suppl 1):21-31. Cooper CB. PMID: 16996896.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    210. Recent experience with open repair of pectus excavatum with minimal cartilage resection. Arch Surg. 2006 Aug; 141(8):823-9. Fonkalsrud EW, Mendoza J, Finn PJ, Cooper CB. PMID: 16927491.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    211. Exercise testing does not have to be complicated. Chron Respir Dis. 2006; 3(2):107-8. Cooper CB. PMID: 16729769.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    212. Solid-phase synthesis of 5-substituted amino pyrazoles. J Comb Chem. 2005 Jul-Aug; 7(4):584-8. Dodd DS, Martinez RL, Kamau M, Ruan Z, Van Kirk K, Cooper CB, Hermsmeier MA, Traeger SC, Poss MA. PMID: 16004502.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    213. Assessment of pulmonary function in COPD. Semin Respir Crit Care Med. 2005 Apr; 26(2):246-52. Cooper CB. PMID: 16088441.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    214. Recent developments in inhaled therapy in stable chronic obstructive pulmonary disease. BMJ. 2005 Mar 19; 330(7492):640-4. Cooper CB, Tashkin DP. PMID: 15774995; PMCID: PMC554913.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    215. Improvement in exercise tolerance with the combination of tiotropium and pulmonary rehabilitation in patients with COPD. Chest. 2005 Mar; 127(3):809-17. Casaburi R, Kukafka D, Cooper CB, Witek TJ, Kesten S. PMID: 15764761.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCTClinical Trials
    216. Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer's disease. Bioorg Med Chem Lett. 2004 Nov 15; 14(22):5521-5. Helal CJ, Sanner MA, Cooper CB, Gant T, Adam M, Lucas JC, Kang Z, Kupchinsky S, Ahlijanian MK, Tate B, Menniti FS, Kelly K, Peterson M. PMID: 15482916.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    217. The role of long-acting bronchodilators in the management of stable COPD. Chest. 2004 Jan; 125(1):249-59. Tashkin DP, Cooper CB. PMID: 14718448.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    218. Respiratory failure. Medicine (Abingdon). 2004 Jan 01; 32(1):95-98. Cooper CB. PMID: 32288560; PMCID: PMC7128432.
      View in: PubMed   Mentions:
    219. Ventilatory and cardiovascular responses to exercise in patients with pectus excavatum. Chest. 2003 Sep; 124(3):870-82. Malek MH, Fonkalsrud EW, Cooper CB. PMID: 12970011.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    220. Comparison of breathing patterns during exercise in patients with obstructive and restrictive ventilatory abnormalities. J Rehabil Res Dev. 2003 Sep-Oct; 40(5):407-14. Nield M, Arora A, Dracup K, Hoo GW, Cooper CB. PMID: 15080225.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    221. Using a collaborative weaning plan to decrease duration of mechanical ventilation and length of stay in the intensive care unit for patients receiving long-term ventilation. Am J Crit Care. 2002 Mar; 11(2):132-40. Henneman E, Dracup K, Ganz T, Molayeme O, Cooper CB. PMID: 11888125.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    222. Ventilatory and gas exchange responses during heavy constant work-rate exercise. Med Sci Sports Exerc. 2002 Jan; 34(1):98-104. Riley MS, Cooper CB. PMID: 11782654.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    223. Exercise in chronic pulmonary disease: limitations and rehabilitation. Med Sci Sports Exerc. 2001 Jul; 33(7 Suppl):S643-6. Cooper CB. PMID: 11462072.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    224. Exercise in chronic pulmonary disease: aerobic exercise prescription. Med Sci Sports Exerc. 2001 Jul; 33(7 Suppl):S671-9. Cooper CB. PMID: 11462076.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
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