William W Stringer

Title(s)Professor of Clinical , Medicine
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    1. Reply to Francescato and Cettolo. Am J Physiol Regul Integr Comp Physiol. 2024 Apr 01; 326(4):R331-R332. Girardi M, Gattoni C, Stringer WW, Rossiter HB, Casaburi R, Ferguson C, Capelli C. PMID: 38518073.
      View in: PubMed   Mentions:    Fields:    
    2. Beyond Spirometry: Linking Wasted Ventilation to Exertional Dyspnea in the Initial Stages of COPD. COPD. 2024 Dec; 21(1):2301549. Neder JA, Santyr G, Zanette B, Kirby M, Pourafkari M, James MD, Vincent SG, Ferguson C, Wang CY, Domnik NJ, Phillips DB, Porszasz J, Stringer WW, O'Donnell DE. PMID: 38348843.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Lack of effect of an in-line filter on cardiopulmonary exercise testing variables in healthy subjects. Eur J Appl Physiol. 2024 Mar; 124(3):1027-1036. Abbasi A, Ahmad K, Ferguson C, Soriano A, Calmelat R, Rossiter HB, Casaburi R, Stringer WW, Porszasz J. PMID: 37803179.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Current definitions of the breathing cycle in alveolar breath-by-breath gas exchange analysis. Am J Physiol Regul Integr Comp Physiol. 2023 11 01; 325(5):R433-R445. Girardi M, Gattoni C, Stringer WW, Rossiter HB, Casaburi R, Ferguson C, Capelli C. PMID: 37519253.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Letter to the editor in response to Hoskote "Corrected formula for rectangular area ratio (RAR), a parameter used to quantify airflow limitation on expiratory flow-volume curves" Respiratory Medicine 2022; 204: 107032. Respir Med. 2023 Aug-Sep; 215:107304. Porszasz J, Wang CY, Ferguson C, Ma S, Girardi M, Stringer WW. PMID: 37257784.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Exercise-induced increases in "liver function tests" in a healthy adult male: Is there a knowledge gap in primary care? J Family Med Prim Care. 2023 Jan; 12(1):177-180. Tiller NB, Stringer WW. PMID: 37025214; PMCID: PMC10071916.
      View in: PubMed   Mentions: 2  
    7. Diffusing Capacity and Mortality in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2023 01; 20(1):38-46. Balasubramanian A, Putcha N, MacIntyre NR, Jensen RL, Kinney G, Stringer WW, Hersh CP, Bowler RP, Casaburi R, Han MK, Porszasz J, Barr RG, Regan E, Make BJ, Hansel NN, Wise RA, McCormack MC. PMID: 35969416; PMCID: PMC9819262.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function. N Engl J Med. 2022 09 29; 387(13):1173-1184. Han MK, Ye W, Wang D, White E, Arjomandi M, Barjaktarevic IZ, Brown SA, Buhr RG, Comellas AP, Cooper CB, Criner GJ, Dransfield MT, Drescher F, Folz RJ, Hansel NN, Kalhan R, Kaner RJ, Kanner RE, Krishnan JA, Lazarus SC, Maddipati V, Martinez FJ, Mathews A, Meldrum C, McEvoy C, Nyunoya T, Rogers L, Stringer WW, Wendt CH, Wise RA, Wisniewski SR, Sciurba FC, Woodruff PG, RETHINC Study Group. PMID: 36066078; PMCID: PMC9741866.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    9. Heart Rate Variability on 10-Second Electrocardiogram and Risk of Acute Exacerbation of COPD: A Secondary Analysis of the BLOCK COPD Trial. Chronic Obstr Pulm Dis. 2022 Apr 29; 9(2):226-236. MacDonald DM, Mkorombindo T, Ling SX, Adabag S, Casaburi R, Connett JE, Helgeson ES, Porszasz J, Rossiter HB, Stringer WW, Voelker H, Zhao D, Dransfield MT, Kunisaki KM. PMID: 35403415; PMCID: PMC9166329.
      View in: PubMed   Mentions: 6  
    10. A randomized, crossover, placebo controlled, double-blind trial of the effects of tiotropium-olodaterol on neuromuscular performance during exercise in COPD. J Appl Physiol (1985). 2022 05 01; 132(5):1145-1153. Cao M, Calmelat RA, Kierstead P, Carraro N, Stringer WW, Porszasz J, Casaburi R, Rossiter HB. PMID: 35323052; PMCID: PMC9054255.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Chronotropic index during 6-minute walk and acute respiratory events in COPDGene. Respir Med. 2022 04; 194:106775. Macdonald DM, Palzer EF, Abbasi A, Baldomero AK, Bhatt SP, Casaburi R, Connett JE, Dransfield MT, Gaeckle NT, Mkorombindo T, Rossiter HB, Stringer WW, Tiller NB, Wendt CH, Zhao D, Kunisaki KM. PMID: 35203009; PMCID: PMC8932051.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Chronotropic Index and Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Secondary Analysis of BLOCK COPD. Ann Am Thorac Soc. 2021 11; 18(11):1795-1802. MacDonald DM, Helgeson ES, Adabag S, Casaburi R, Connett JE, Stringer WW, Voelker H, Dransfield MT, Kunisaki KM. PMID: 33784233.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    13. Identifying a Heart Rate Recovery Criterion After a 6-Minute Walk Test in COPD. Int J Chron Obstruct Pulmon Dis. 2021; 16:2545-2560. Zhao D, Abbasi A, Casaburi R, Adami A, Tiller NB, Yuan W, Yee C, Jendzjowsky NG, MacDonald DM, Kunisaki KM, Stringer WW, Porszasz J, Make BJ, Bowler RP, Rossiter HB, COPDGene Investigators. PMID: 34511898; PMCID: PMC8427685.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    14. Mind and Body: The Exercise Connection. Chest. 2021 09; 160(3):803-804. Stringer WW. PMID: 34488956.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Haemoglobin as a biomarker for clinical outcomes in chronic obstructive pulmonary disease. ERJ Open Res. 2021 Jul; 7(3). Balasubramanian A, Henderson RJ, Putcha N, Fawzy A, Raju S, Hansel NN, MacIntyre NR, Jensen RL, Kinney GL, Stringer WW, Hersh CP, Bowler RP, Casaburi R, Han MK, Porszasz J, Make BJ, McCormack MC, Wise RA. PMID: 34322549; PMCID: PMC8311135.
      View in: PubMed   Mentions: 2  
    16. Dynamic airway function during exercise in COPD assessed via impulse oscillometry before and after inhaled bronchodilators. J Appl Physiol (1985). 2021 07 01; 131(1):326-338. Tiller NB, Cao M, Lin F, Yuan W, Wang CY, Abbasi A, Calmelat R, Soriano A, Rossiter HB, Casaburi R, Stringer WW, Porszasz J. PMID: 34013748; PMCID: PMC8325613.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. The effect of long-acting dual bronchodilator therapy on exercise tolerance, dynamic hyperinflation, and dead space during constant work rate exercise in COPD. J Appl Physiol (1985). 2021 06 01; 130(6):2009-2018. Stringer WW, Porszasz J, Cao M, Rossiter HB, Siddiqui S, Rennard S, Casaburi R. PMID: 33914661; PMCID: PMC8526332.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Transcutaneous PCO2 for Exercise Gas Exchange Efficiency in Chronic Obstructive Pulmonary Disease. COPD. 2021 02; 18(1):16-25. Cao M, Stringer WW, Corey S, Orogian A, Cao R, Calmelat R, Lin F, Casaburi R, Rossiter HB, Porszasz J. PMID: 33455452.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Safety and Stability of Pulmonary Function in Patients with Decreased Respiratory Function Treated for Spasticity with OnabotulinumtoxinA. Toxins (Basel). 2020 10 19; 12(10). Ayyoub Z, Brashear A, Banach M, Schoene R, Stringer W, Boodhoo T, Yushmanova I, Dimitrova R, Brin MF. PMID: 33086749; PMCID: PMC7589715.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Response. Chest. 2020 10; 158(4):1781-1782. Morris TA, Porszasz J, Stringer WW. PMID: 33036092.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Are We Treating Heart Failure in Patients with Chronic Obstructive Pulmonary Disease Appropriately? Ann Am Thorac Soc. 2020 08; 17(8):932-934. Stringer WW. PMID: 32735167; PMCID: PMC7393790.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. A New Bronchodilator Response Grading Strategy Identifies Distinct Patient Populations. Ann Am Thorac Soc. 2019 12; 16(12):1504-1517. Hansen JE, Dilektasli AG, Porszasz J, Stringer WW, Pak Y, Rossiter HB, Casaburi R. PMID: 31404502; PMCID: PMC6956832.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    23. Dyspnea Postpulmonary Embolism From Physiological Dead Space Proportion and Stroke Volume Defects During Exercise. Chest. 2020 04; 157(4):936-944. Fernandes TM, Alotaibi M, Strozza DM, Stringer WW, Porszasz J, Faulkner GG, Castro CF, Tran DA, Morris TA. PMID: 31759962.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    24. COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease. Chronic Obstr Pulm Dis. 2019 Nov; 6(5):384-399. Lowe KE, Regan EA, Anzueto A, Austin E, Austin JHM, Beaty TH, Benos PV, Benway CJ, Bhatt SP, Bleecker ER, Bodduluri S, Bon J, Boriek AM, Boueiz AR, Bowler RP, Budoff M, Casaburi R, Castaldi PJ, Charbonnier JP, Cho MH, Comellas A, Conrad D, Costa Davis C, Criner GJ, Curran-Everett D, Curtis JL, DeMeo DL, Diaz AA, Dransfield MT, Dy JG, Fawzy A, Fleming M, Flenaugh EL, Foreman MG, Fortis S, Gebrekristos H, Grant S, Grenier PA, Gu T, Gupta A, Han MK, Hanania NA, Hansel NN, Hayden LP, Hersh CP, Hobbs BD, Hoffman EA, Hogg JC, Hokanson JE, Hoth KF, Hsiao A, Humphries S, Jacobs K, Jacobson FL, Kazerooni EA, Kim V, Kim WJ, Kinney GL, Koegler H, Lutz SM, Lynch DA, MacIntye NR, Make BJ, Marchetti N, Martinez FJ, Maselli DJ, Mathews AM, McCormack MC, McDonald MN, McEvoy CE, Moll M, Molye SS, Murray S, Nath H, Newell JD, Occhipinti M, Paoletti M, Parekh T, Pistolesi M, Pratte KA, Putcha N, Ragland M, Reinhardt JM, Rennard SI, Rosiello RA, Ross JC, Rossiter HB, Ruczinski I, San Jose Estepar R, Sciurba FC, Sieren JC, Singh H, Soler X, Steiner RM, Strand MJ, Stringer WW, Tal-Singer R, Thomashow B, Vegas Sánchez-Ferrero G, Walsh JW, Wan ES, Washko GR, Michael Wells J, Wendt CH, Westney G, Wilson A, Wise RA, Yen A, Young K, Yun J, Silverman EK, Crapo JD. PMID: 31710793; PMCID: PMC7020846.
      View in: PubMed   Mentions: 94  
    25. Metoprolol for the Prevention of Acute Exacerbations of COPD. N Engl J Med. 2019 12 12; 381(24):2304-2314. Dransfield MT, Voelker H, Bhatt SP, Brenner K, Casaburi R, Come CE, Cooper JAD, Criner GJ, Curtis JL, Han MK, Hatipoglu U, Helgeson ES, Jain VV, Kalhan R, Kaminsky D, Kaner R, Kunisaki KM, Lambert AA, Lammi MR, Lindberg S, Make BJ, Martinez FJ, McEvoy C, Panos RJ, Reed RM, Scanlon PD, Sciurba FC, Smith A, Sriram PS, Stringer WW, Weingarten JA, Wells JM, Westfall E, Lazarus SC, Connett JE, BLOCK COPD Trial Group. PMID: 31633896; PMCID: PMC7416529.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    26. Diffusing Capacity of Carbon Monoxide in Assessment of COPD. Chest. 2019 12; 156(6):1111-1119. Balasubramanian A, MacIntyre NR, Henderson RJ, Jensen RL, Kinney G, Stringer WW, Hersh CP, Bowler RP, Casaburi R, Han MK, Porszasz J, Barr RG, Make BJ, Wise RA, McCormack MC. PMID: 31352035; PMCID: PMC7242635.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    27. Physiologic Insights from the COPD Genetic Epidemiology Study. Chronic Obstr Pulm Dis. 2019 07 24; 6(3):256-266. Stringer WW, Porszasz J, Bhatt SP, McCormack MC, Make BJ, Casaburi R. PMID: 31342731; PMCID: PMC6872216.
      View in: PubMed   Mentions: 7  
    28. Physiologic Effects of Oxygen Supplementation During Exercise in Chronic Obstructive Pulmonary Disease. Clin Chest Med. 2019 06; 40(2):385-395. Dilektasli AG, Porszasz J, Stringer WW, Casaburi R. PMID: 31078216.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    29. Exercise Capacity in Unilateral Diaphragm Paralysis: The Effect of Obesity. Pulm Med. 2019; 2019:1090982. Richman PS, Yeung P, Bilfinger TV, Yang J, Stringer WW. PMID: 31057965; PMCID: PMC6463570.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. The Role of Cardiopulmonary Exercise Testing (CPET) in Pulmonary Rehabilitation (PR) of Chronic Obstructive Pulmonary Disease (COPD) Patients. COPD. 2018 12; 15(6):621-631. Stringer W, Marciniuk D. PMID: 30595047.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    31. Reliability and Physiological Interpretation of Pulmonary Gas Exchange by "Circulatory Equivalents" in Chronic Heart Failure. J Am Heart Assoc. 2018 03 27; 7(7). Tan C, Rossiter HB, Porszasz J, Bowen TS, Witte KK, Stringer WW, Casaburi R, Hansen JE. PMID: 29588313; PMCID: PMC5907590.
      View in: PubMed   Mentions: 1     Fields:    
    32. Physical activity to improve health: do not forget that the lungs benefit too. Eur Respir J. 2018 02; 51(2). Puente-Maestu L, Stringer WW. PMID: 29386339.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Mechanisms That Modulate Peripheral Oxygen Delivery during Exercise in Heart Failure. Ann Am Thorac Soc. 2017 Jul; 14(Supplement_1):S40-S47. Kisaka T, Stringer WW, Koike A, Agostoni P, Wasserman K. PMID: 28679061.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    34. Reassessment of an Asthma Diagnosis. JAMA. 2017 05 02; 317(17):1801-1802. Jain VV, Stringer W. PMID: 28464136.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Hormesis, mithridatism and Paracelsus: A little oxidative stress goes a long way. Hypertens Res. 2017 01; 40(1):29-30. Stringer WW, Rossiter HB. PMID: 27511052.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. A Novel Spirometric Measure Identifies Mild COPD Unidentified by Standard Criteria. Chest. 2016 Nov; 150(5):1080-1090. Dilektasli AG, Porszasz J, Casaburi R, Stringer WW, Bhatt SP, Pak Y, Rossiter HB, Washko G, Castaldi PJ, Estepar RSJ, Hansen JE, COPDGene investigators. PMID: 27452770; PMCID: PMC5103018.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    37. An interesting case of profound hypoxemia. Exp Mol Pathol. 2016 Apr; 100(2):321-4. Fu J, Nguyen L, Nguyen E, Lau N, Ji P, French SW, Stringer WW. PMID: 26939911.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Better parameters of ventilation-CO₂output relationship predict death in CHF patients. Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Nov; 31(6):508-16. Yao YX, Sun XG, Zheng Z, Wang GZ, Hansen JE, Stringer WW, Wasserman K, Hu SS. PMID: 27215018.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Re-Defining Lower Limit of Normal for FEV1/FEV6, FEV1/FVC, FEV3/FEV6 and FEV3/FVC to Improve Detection of Airway Obstruction. Chronic Obstr Pulm Dis. 2015 Mar 10; 2(2):94-102. Hansen JE, Porszasz J, Casaburi R, Stringer WW. PMID: 28848835; PMCID: PMC5556964.
      View in: PubMed   Mentions: 15  
    40. Lepidic predominant adenocarcinoma with aerogenous spread of mucin in a young patient -- a case report. Exp Mol Pathol. 2014 Jun; 96(3):400-4. Nguyen E, Hakimi M, Chavoshan B, Stringer W, French SW. PMID: 24768586.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    41. Capturing the diagnosis: an internal medicine education program to improve documentation. Am J Med. 2013 Aug; 126(8):739-743.e1. Spellberg B, Harrington D, Black S, Sue D, Stringer W, Witt M. PMID: 23791207.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    42. A simple new visualization of exercise data discloses pathophysiology and severity of heart failure. J Am Heart Assoc. 2012 Jun; 1(3):e001883. Hansen JE, Sun XG, Stringer WW. PMID: 23130146; PMCID: PMC3487328.
      View in: PubMed   Mentions: 6     Fields:    
    43. A controlled investigation of optimal internal medicine ward team structure at a teaching hospital. PLoS One. 2012; 7(4):e35576. Spellberg B, Lewis RJ, Sue D, Chavoshan B, Vintch J, Munekata M, Kim C, Lanks C, Witt MD, Stringer W, Harrington D. PMID: 22532860; PMCID: PMC3330818.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. Cardiopulmonary exercise testing: does it improve perioperative care and outcome? Curr Opin Anaesthesiol. 2012 Apr; 25(2):178-84. Stringer W, Casaburi R, Older P. PMID: 22327200.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    45. Oxygen uptake efficiency plateau best predicts early death in heart failure. Chest. 2012 May; 141(5):1284-1294. Sun XG, Hansen JE, Stringer WW. PMID: 22030802; PMCID: PMC4694089.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    46. Oxygen uptake efficiency plateau: physiology and reference values. Eur J Appl Physiol. 2012 Mar; 112(3):919-28. Sun XG, Hansen JE, Stringer WW. PMID: 21695524.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    47. Arterial H+ regulation during exercise in humans. Respir Physiol Neurobiol. 2011 Sep 15; 178(2):191-5. Wasserman K, Beaver WL, Sun XG, Stringer WW. PMID: 21689788.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    48. Cardiopulmonary exercise testing: current applications. Expert Rev Respir Med. 2010 Apr; 4(2):179-88. Stringer WW. PMID: 20406084.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    49. A controlled trial of the effects of leg training on breathing pattern and dynamic hyperinflation in severe COPD. Lung. 2006 May-Jun; 184(3):159-67. Puente-Maestu L, Abad YM, Pedraza F, Sánchez G, Stringer WW. PMID: 16902841.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    50. Hyperinflation and its management in COPD. Int J Chron Obstruct Pulmon Dis. 2006; 1(4):381-400. Puente-Maestu L, Stringer WW. PMID: 18044095; PMCID: PMC2707802.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    51. A matched comparison of serum lipids between hemodialysis patients and nondialysis morbid controls. Hemodial Int. 2005 Jul; 9(3):314-24. Kalantar-Zadeh K, Kilpatrick RD, Kopple JD, Stringer WW. PMID: 16191083.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    52. Dyspnea, hemoptysis, and perihilar infiltrates in a 35-year-old man. Chest. 2005 Apr; 127(4):1437-41. Jung C, Karpouzas G, Stringer WW. PMID: 15821227.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    53. Statement on exercise: American College of Chest Physicians/American Thoracic Society--exercise for fun or profit? Chest. 2005 Mar; 127(3):1072-3; author reply 1073-4. Stringer WW, Wasserman K. PMID: 15764797.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    54. Antibodies reactive with C-terminus of the second conserved region of HIV-1gp120 as possible prognostic marker and therapeutic agent for HIV disease. J Clin Virol. 2004 Dec; 31 Suppl 1:S39-44. Veljkovic N, Branch DR, Metlas R, Prljic J, Manfredi R, Stringer WW, Veljkovic V. PMID: 15567092.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    55. Non-linear cardiac output dynamics during ramp-incremental cycle ergometry. Eur J Appl Physiol. 2005 Mar; 93(5-6):634-9. Stringer WW, Whipp BJ, Wasserman K, Pórszász J, Christenson P, French WJ. PMID: 15578205.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    56. Partial anomalous pulmonary venous return: case report and review of the literature. Catheter Cardiovasc Interv. 2003 Apr; 58(4):548-52. AboulHosn JA, Criley JM, Stringer WW. PMID: 12652510.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    57. Training improves muscle oxidative capacity and oxygenation recovery kinetics in patients with chronic obstructive pulmonary disease. Eur J Appl Physiol. 2003 Feb; 88(6):580-7. Puente-Maestu L, Tena T, Trascasa C, Pérez-Parra J, Godoy R, García MJ, Stringer WW. PMID: 12560958.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    58. Metabolic Syndromes Associated With HIV: Mitigating the Side Effects of Drug Therapy. Phys Sportsmed. 2001 Dec; 29(12):19-26. Stringer WW, Sattler FR. PMID: 20086559.
      View in: PubMed   Mentions: 1     Fields:    
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