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Itzhak Fried

Title(s)Professor-in-Residence, Neurosurgery
SchoolMedicine
Address10920 WILSHIRE BOULEVARD 1800
LOS ANGELES CA 90024
Phone58409
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    Other Positions
    Title(s)Professor-in-Residence, Psychiatry and Biobehavioral Sciences


    Collapse Research 
    Collapse Research Activities and Funding
    Memory consolidation during sleep studied by direct neuronal recording and stimulation inside human brain
    NIH/NINDS U01NS108930Sep 30, 2018 - Aug 31, 2020
    Role: Principal Investigator
    Mechanisms of Memory Enhancement by Deep Brain Stimulation in Humans
    NIH/NINDS R01NS084017Jun 1, 2013 - May 31, 2018
    Role: Principal Investigator
    Neuronal Correlates of Memory in the Human Temporal Lobe
    NIH/NINDS R56NS033221Sep 16, 1996 - Aug 31, 2014
    Role: Principal Investigator
    Neuronal Correlates of Memory in the Human Temporal Lobe
    NIH/NINDS R01NS033221Sep 16, 1996 - Sep 29, 2012
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Boundary-anchored neural mechanisms of location-encoding for self and others. Nature. 2020 Dec 23. Stangl M, Topalovic U, Inman CS, Hiller S, Villaroman D, Aghajan ZM, Christov-Moore L, Hasulak NR, Rao VR, Halpern CH, Eliashiv D, Fried I, Suthana N. PMID: 33361808.
      View in: PubMed   Mentions:    Fields:    
    2. Stimulation of the right entorhinal white matter enhances visual memory encoding in humans. Brain Stimul. 2020 Dec 03; 14(1):131-140. Mankin EA, Aghajan ZM, Schuette P, Tran ME, Tchemodanov N, Titiz A, Kalender G, Eliashiv D, Stern J, Weiss SA, Kirsch D, Knowlton B, Fried I, Suthana N. PMID: 33279717.
      View in: PubMed   Mentions:    Fields:    
    3. Single-cell activity in human STG during perception of phonemes is organized according to manner of articulation. Neuroimage. 2020 Oct 24; 226:117499. Lakertz Y, Ossmy O, Friedmann N, Mukamel R, Fried I. PMID: 33186717.
      View in: PubMed   Mentions:    Fields:    
    4. Wireless Programmable Recording and Stimulation of Deep Brain Activity in Freely Moving Humans. Neuron. 2020 Oct 28; 108(2):322-334.e9. Topalovic U, Aghajan ZM, Villaroman D, Hiller S, Christov-Moore L, Wishard TJ, Stangl M, Hasulak NR, Inman CS, Fields TA, Rao VR, Eliashiv D, Fried I, Suthana N. PMID: 32946744.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. The role of mPFC and MTL neurons in human choice under goal-conflict. Nat Commun. 2020 06 24; 11(1):3192. Gazit T, Gonen T, Gurevitch G, Cohen N, Strauss I, Zeevi Y, Yamin H, Fahoum F, Hendler T, Fried I. PMID: 32581214.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Preoperative localization of seizure onset zones by magnetic source imaging, EEG-correlated functional MRI, and their combination. J Neurosurg. 2020 May 15; 1-7. Berger A, Cohen N, Fahoum F, Medvedovsky M, Meller A, Ekstein D, Benifla M, Aizenstein O, Fried I, Gazit T, Strauss I. PMID: 32413858.
      View in: PubMed   Mentions:    Fields:    
    7. Modulation of Human Memory by Deep Brain Stimulation of the Entorhinal-Hippocampal Circuitry. Neuron. 2020 04 22; 106(2):218-235. Mankin EA, Fried I. PMID: 32325058.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Ripples Have Distinct Spectral Properties and Phase-Amplitude Coupling With Slow Waves, but Indistinct Unit Firing, in Human Epileptogenic Hippocampus. Front Neurol. 2020; 11:174. Weiss SA, Song I, Leng M, Pastore T, Slezak D, Waldman Z, Orosz I, Gorniak R, Donmez M, Sharan A, Wu C, Fried I, Sperling MR, Bragin A, Engel J, Nir Y, Staba R. PMID: 32292384.
      View in: PubMed   Mentions:
    9. Spatial distribution and hemispheric asymmetry of electrically evoked experiential phenomena in the human brain. J Neurosurg. 2020 07; 133(1):54-62. Andelman-Gur MM, Gazit T, Andelman F, Kipervasser S, Kramer U, Neufeld MY, Fried I, Fahoum F. PMID: 31200379.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. A Tradeoff in the Neural Code across Regions and Species. Cell. 2019 01 24; 176(3):597-609.e18. Pryluk R, Kfir Y, Gelbard-Sagiv H, Fried I, Paz R. PMID: 30661754.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    11. Low-voltage fast seizures in humans begin with increased interneuron firing. Ann Neurol. 2018 10; 84(4):588-600. Elahian B, Lado NE, Mankin E, Vangala S, Misra A, Moxon K, Fried I, Sharan A, Yeasin M, Staba R, Bragin A, Avoli M, Sperling MR, Engel J, Weiss SA. PMID: 30179277.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    12. Phase-tuned neuronal firing encodes human contextual representations for navigational goals. Elife. 2018 06 22; 7. Watrous AJ, Miller J, Qasim SE, Fried I, Jacobs J. PMID: 29932417.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    13. Pace of movement: the role of single neurons in the subthalamic nucleus. J Neurosurg. 2018 Jun 01; 1-6. Tankus A, Mirelman A, Giladi N, Fried I, Hausdorff JM. PMID: 29932375.
      View in: PubMed   Mentions: 1     Fields:    
    14. Human single neuron activity precedes emergence of conscious perception. Nat Commun. 2018 05 25; 9(1):2057. Gelbard-Sagiv H, Mudrik L, Hill MR, Koch C, Fried I. PMID: 29802308.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    15. Conflict monitoring mechanism at the single-neuron level in the human ventral anterior cingulate cortex. Neuroimage. 2018 07 15; 175:45-55. Shapira-Lichter I, Strauss I, Oren N, Gazit T, Sammartino F, Giacobbe P, Kennedy S, Hutchison WD, Fried I, Hendler T, Lozano AM. PMID: 29551460.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. Theta Oscillations in the Human Medial Temporal Lobe during Real-World Ambulatory Movement. Curr Biol. 2017 Dec 18; 27(24):3743-3751.e3. M Aghajan Z, Schuette P, Fields TA, Tran ME, Siddiqui SM, Hasulak NR, Tcheng TK, Eliashiv D, Mankin EA, Stern J, Fried I, Suthana N. PMID: 29199073.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    17. Volition and Action in the Human Brain: Processes, Pathologies, and Reasons. J Neurosci. 2017 11 08; 37(45):10842-10847. Fried I, Haggard P, He BJ, Schurger A. PMID: 29118213.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    18. Selective neuronal lapses precede human cognitive lapses following sleep deprivation. Nat Med. 2017 Dec; 23(12):1474-1480. Nir Y, Andrillon T, Marmelshtein A, Suthana N, Cirelli C, Tononi G, Fried I. PMID: 29106402.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    19. Utilization of independent component analysis for accurate pathological ripple detection in intracranial EEG recordings recorded extra- and intra-operatively. Clin Neurophysiol. 2018 01; 129(1):296-307. Shimamoto S, Waldman ZJ, Orosz I, Song I, Bragin A, Fried I, Engel J, Staba R, Sharan A, Wu C, Sperling MR, Weiss SA. PMID: 29113719.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    20. Theta-burst microstimulation in the human entorhinal area improves memory specificity. Elife. 2017 10 24; 6. Titiz AS, Hill MRH, Mankin EA, M Aghajan Z, Eliashiv D, Tchemodanov N, Maoz U, Stern J, Tran ME, Schuette P, Behnke E, Suthana NA, Fried I. PMID: 29063831.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    21. Failed epilepsy surgery deserves a second chance. Clin Neurol Neurosurg. 2017 Dec; 163:110-115. Reed CM, Dewar S, Fried I, Engel J, Eliashiv D. PMID: 29096138.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. A method for the topographical identification and quantification of high frequency oscillations in intracranial electroencephalography recordings. Clin Neurophysiol. 2018 01; 129(1):308-318. Waldman ZJ, Shimamoto S, Song I, Orosz I, Bragin A, Fried I, Engel J, Staba R, Sperling MR, Weiss SA. PMID: 29122445.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    23. Bimodal coupling of ripples and slower oscillations during sleep in patients with focal epilepsy. Epilepsia. 2017 11; 58(11):1972-1984. Song I, Orosz I, Chervoneva I, Waldman ZJ, Fried I, Wu C, Sharan A, Salamon N, Gorniak R, Dewar S, Bragin A, Engel J, Sperling MR, Staba R, Weiss SA. PMID: 28948998.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    24. Persistent Single-Neuron Activity during Working Memory in the Human Medial Temporal Lobe. Curr Biol. 2017 Apr 03; 27(7):1026-1032. Kornblith S, Quian Quiroga R, Koch C, Fried I, Mormann F. PMID: 28318972.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    25. Scene-selective coding by single neurons in the human parahippocampal cortex. Proc Natl Acad Sci U S A. 2017 01 31; 114(5):1153-1158. Mormann F, Kornblith S, Cerf M, Ison MJ, Kraskov A, Tran M, Knieling S, Quian Quiroga R, Koch C, Fried I. PMID: 28096381.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    26. Long-term coding of personal and universal associations underlying the memory web in the human brain. Nat Commun. 2016 11 15; 7:13408. De Falco E, Ison MJ, Fried I, Quian Quiroga R. PMID: 27845773.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    27. Ripples on spikes show increased phase-amplitude coupling in mesial temporal lobe epilepsy seizure-onset zones. Epilepsia. 2016 11; 57(11):1916-1930. Weiss SA, Orosz I, Salamon N, Moy S, Wei L, Van't Klooster MA, Knight RT, Harper RM, Bragin A, Fried I, Engel J, Staba RJ. PMID: 27723936.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    28. Observational learning computations in neurons of the human anterior cingulate cortex. Nat Commun. 2016 09 06; 7:12722. Hill MR, Boorman ED, Fried I. PMID: 27598687.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    29. Responses of neurons in the medial temporal lobe during encoding and recognition of face-scene pairs. Neuropsychologia. 2016 09; 90:200-9. Viskontas IV, Knowlton BJ, Fried I. PMID: 27424273.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    30. Characterization of long-range functional connectivity in epileptic networks by neuronal spike-triggered local field potentials. J Neural Eng. 2016 Apr; 13(2):026031. Lopour BA, Staba RJ, Stern JM, Fried I, Ringach DL. PMID: 26975603.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    31. Probabilistic machine learning for the evaluation of presurgical language dominance. J Neurosurg. 2016 08; 125(2):481-93. Gazit T, Andelman F, Glikmann-Johnston Y, Gonen T, Solski A, Shapira-Lichter I, Ovadia M, Kipervasser S, Neufeld MY, Fried I, Hendler T, Perry D. PMID: 26722848.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Ictal onset patterns of local field potentials, high frequency oscillations, and unit activity in human mesial temporal lobe epilepsy. Epilepsia. 2016 Jan; 57(1):111-21. Weiss SA, Alvarado-Rojas C, Bragin A, Behnke E, Fields T, Fried I, Engel J, Staba R. PMID: 26611159.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    33. Safety, efficacy, and life satisfaction following epilepsy surgery in patients aged 60 years and older. J Neurosurg. 2016 Apr; 124(4):945-51. Dewar S, Eliashiv D, Walshaw PD, Engel J, Fried I, Moseley BD. PMID: 26381254.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Single-neuron activity and eye movements during human REM sleep and awake vision. Nat Commun. 2015 Aug 11; 6:7884. Andrillon T, Nir Y, Cirelli C, Tononi G, Fried I. PMID: 26262924.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    35. Specific responses of human hippocampal neurons are associated with better memory. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10503-8. Suthana NA, Parikshak NN, Ekstrom AD, Ison MJ, Knowlton BJ, Bookheimer SY, Fried I. PMID: 26240357.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    36. Rapid Encoding of New Memories by Individual Neurons in the Human Brain. Neuron. 2015 Jul 01; 87(1):220-30. Ison MJ, Quian Quiroga R, Fried I. PMID: 26139375.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    37. Brain stimulation and memory. Brain. 2015 Jul; 138(Pt 7):1766-7. Fried I. PMID: 26106093.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    38. Decoding speech perception from single cell activity in humans. Neuroimage. 2015 Aug 15; 117:151-9. Ossmy O, Fried I, Mukamel R. PMID: 25976925.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    39. Ictal depth EEG and MRI structural evidence for two different epileptogenic networks in mesial temporal lobe epilepsy. PLoS One. 2015; 10(4):e0123588. Memarian N, Madsen SK, Macey PM, Fried I, Engel J, Thompson PM, Staba RJ. PMID: 25849340.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    40. Repeating spatial activations in human entorhinal cortex. Curr Biol. 2015 Apr 20; 25(8):1080-5. Miller JF, Fried I, Suthana N, Jacobs J. PMID: 25843029.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    41. Preconscious prediction of a driver's decision using intracranial recordings. J Cogn Neurosci. 2015 Aug; 27(8):1492-502. Perez O, Mukamel R, Tankus A, Rosenblatt JD, Yeshurun Y, Fried I. PMID: 25761001.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    42. Single-cell responses to face adaptation in the human medial temporal lobe. Neuron. 2014 Oct 22; 84(2):363-9. Quian Quiroga R, Kraskov A, Mormann F, Fried I, Koch C. PMID: 25263754.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    43. Distinct iEEG activity patterns in temporal-limbic and prefrontal sites induced by emotional intentionality. Cortex. 2014 Nov; 60:121-38. Singer N, Podlipsky I, Esposito F, Okon-Singer H, Andelman F, Kipervasser S, Neufeld MY, Goebel R, Fried I, Hendler T. PMID: 25288171.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. Timing of single-neuron and local field potential responses in the human medial temporal lobe. Curr Biol. 2014 Feb 03; 24(3):299-304. Rey HG, Fried I, Quian Quiroga R. PMID: 24462002.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    45. Limbic neuromodulation: implications for addiction, posttraumatic stress disorder, and memory. Neurosurg Clin N Am. 2014 Jan; 25(1):137-45. Bari A, Niu T, Langevin JP, Fried I. PMID: 24262905.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. Emergence of sensory patterns during sleep highlights differential dynamics of REM and non-REM sleep stages. J Neurosci. 2013 Sep 11; 33(37):14715-28. Ramot M, Fisch L, Davidesco I, Harel M, Kipervasser S, Andelman F, Neufeld MY, Kramer U, Fried I, Malach R. PMID: 24027272.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. Coding of information in the phase of local field potentials within human medial temporal lobe. Neuron. 2013 Aug 07; 79(3):594-606. Lopour BA, Tavassoli A, Fried I, Ringach DL. PMID: 23932002.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    48. Direct recordings of grid-like neuronal activity in human spatial navigation. Nat Neurosci. 2013 Sep; 16(9):1188-90. Jacobs J, Weidemann CT, Miller JF, Solway A, Burke JF, Wei XX, Suthana N, Sperling MR, Sharan AD, Fried I, Kahana MJ. PMID: 23912946.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansCells
    49. Deep brain stimulation for enhancement of learning and memory. Neuroimage. 2014 Jan 15; 85 Pt 3:996-1002. Suthana N, Fried I. PMID: 23921099.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    50. Improved P300 speller performance using electrocorticography, spectral features, and natural language processing. Clin Neurophysiol. 2013 Jul; 124(7):1321-8. Speier W, Fried I, Pouratian N. PMID: 23465430.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    51. Brain cells for grandmother. Sci Am. 2013 Feb; 308(2):30-5. Quiroga RQ, Fried I, Koch C. PMID: 23367781.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    52. Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction. Nat Commun. 2013; 4:1547. Blouin AM, Fried I, Wilson CL, Staba RJ, Behnke EJ, Lam HA, Maidment NT, Karlsson KÆ, Lapierre JL, Siegel JM. PMID: 23462990.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimals
    53. Sparse decoding of multiple spike trains for brain-machine interfaces. J Neural Eng. 2012 Oct; 9(5):054001. Tankus A, Fried I, Shoham S. PMID: 22954906.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    54. A widely distributed spectral signature of task-negative electrocorticography responses revealed during a visuomotor task in the human cortex. J Neurosci. 2012 Aug 01; 32(31):10458-69. Ramot M, Fisch L, Harel M, Kipervasser S, Andelman F, Neufeld MY, Kramer U, Fried I, Malach R. PMID: 22855795.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    55. Vagal nerve stimulation for refractory epilepsy: the surgical procedure and complications in 100 implantations by a single medical center. Eur Arch Otorhinolaryngol. 2013 Jan; 270(1):355-8. Horowitz G, Amit M, Fried I, Neufeld MY, Sharf L, Kramer U, Fliss DM. PMID: 22836871.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    56. Percepts to recollections: insights from single neuron recordings in the human brain. Trends Cogn Sci. 2012 Aug; 16(8):427-36. Suthana N, Fried I. PMID: 22795560.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    57. Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. JAMA. 2012 Mar 07; 307(9):922-30. Engel J, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, Sperling MR, Gardiner I, Erba G, Fried I, Jacobs M, Vinters HV, Mintzer S, Kieburtz K. PMID: 22396514.
      View in: PubMed   Mentions: 157     Fields:    Translation:Humans
    58. Memory enhancement and deep-brain stimulation of the entorhinal area. N Engl J Med. 2012 Feb 09; 366(6):502-10. Suthana N, Haneef Z, Stern J, Mukamel R, Behnke E, Knowlton B, Fried I. PMID: 22316444.
      View in: PubMed   Mentions: 117     Fields:    Translation:Humans
    59. Structured neuronal encoding and decoding of human speech features. Nat Commun. 2012; 3:1015. Tankus A, Fried I, Shoham S. PMID: 22910361.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    60. Sleep spindles in humans: insights from intracranial EEG and unit recordings. J Neurosci. 2011 Dec 07; 31(49):17821-34. Andrillon T, Nir Y, Staba RJ, Ferrarelli F, Cirelli C, Tononi G, Fried I. PMID: 22159098.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansCells
    61. Gray matter loss correlates with mesial temporal lobe neuronal hyperexcitability inside the human seizure-onset zone. Epilepsia. 2012 Jan; 53(1):25-34. Staba RJ, Ekstrom AD, Suthana NA, Burggren A, Fried I, Engel J, Bookheimer SY. PMID: 22126325.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    62. Visuomotor coordination and motor representation by human temporal lobe neurons. J Cogn Neurosci. 2012 Mar; 24(3):600-10. Tankus A, Fried I. PMID: 22066588.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    63. Human intracranial recordings and cognitive neuroscience. Annu Rev Psychol. 2012; 63:511-37. Mukamel R, Fried I. PMID: 21943170.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    64. A category-specific response to animals in the right human amygdala. Nat Neurosci. 2011 Aug 28; 14(10):1247-9. Mormann F, Dubois J, Kornblith S, Milosavljevic M, Cerf M, Ison M, Tsuchiya N, Kraskov A, Quiroga RQ, Adolphs R, Fried I, Koch C. PMID: 21874014.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    65. Selectivity of pyramidal cells and interneurons in the human medial temporal lobe. J Neurophysiol. 2011 Oct; 106(4):1713-21. Ison MJ, Mormann F, Cerf M, Koch C, Fried I, Quiroga RQ. PMID: 21715671.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    66. Regional slow waves and spindles in human sleep. Neuron. 2011 Apr 14; 70(1):153-69. Nir Y, Staba RJ, Andrillon T, Vyazovskiy VV, Cirelli C, Fried I, Tononi G. PMID: 21482364.
      View in: PubMed   Mentions: 253     Fields:    Translation:Humans
    67. Internally generated preactivation of single neurons in human medial frontal cortex predicts volition. Neuron. 2011 Feb 10; 69(3):548-62. Fried I, Mukamel R, Kreiman G. PMID: 21315264.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    68. Behavioral correlates of human hippocampal delta and theta oscillations during navigation. J Neurophysiol. 2011 Apr; 105(4):1747-55. Watrous AJ, Fried I, Ekstrom AD. PMID: 21289136.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCTClinical Trials
    69. On-line, voluntary control of human temporal lobe neurons. Nature. 2010 Oct 28; 467(7319):1104-8. Cerf M, Thiruvengadam N, Mormann F, Kraskov A, Quiroga RQ, Koch C, Fried I. PMID: 20981100.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCellsCTClinical Trials
    70. Invariance of firing rate and field potential dynamics to stimulus modulation rate in human auditory cortex. Hum Brain Mapp. 2011 Aug; 32(8):1181-93. Mukamel R, Nir Y, Harel M, Arieli A, Malach R, Fried I. PMID: 20665720.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    71. Prediction of neurological deficits and recovery after surgery in the supplementary motor area: a prospective study in 26 patients. J Neurosurg. 2010 Dec; 113(6):1152-63. Rosenberg K, Nossek E, Liebling R, Fried I, Shapira-Lichter I, Hendler T, Ram Z. PMID: 20635854.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    72. Antagonistic relationship between gamma power and visual evoked potentials revealed in human visual cortex. Cereb Cortex. 2011 Mar; 21(3):616-24. Privman E, Fisch L, Neufeld MY, Kramer U, Kipervasser S, Andelman F, Yeshurun Y, Fried I, Malach R. PMID: 20624838.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    73. Large-scale microelectrode recordings of high-frequency gamma oscillations in human cortex during sleep. J Neurosci. 2010 Jun 09; 30(23):7770-82. Le Van Quyen M, Staba R, Bragin A, Dickson C, Valderrama M, Fried I, Engel J. PMID: 20534826.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    74. Right-lateralized brain oscillations in human spatial navigation. J Cogn Neurosci. 2010 May; 22(5):824-36. Jacobs J, Korolev IO, Caplan JB, Ekstrom AD, Litt B, Baltuch G, Fried I, Schulze-Bonhage A, Madsen JR, Kahana MJ. PMID: 19400683.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    75. Single-neuron responses in humans during execution and observation of actions. Curr Biol. 2010 Apr 27; 20(8):750-6. Mukamel R, Ekstrom AD, Kaplan J, Iacoboni M, Fried I. PMID: 20381353.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansAnimalsCells
    76. A sense of direction in human entorhinal cortex. Proc Natl Acad Sci U S A. 2010 Apr 06; 107(14):6487-92. Jacobs J, Kahana MJ, Ekstrom AD, Mollison MV, Fried I. PMID: 20308554.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    77. A neural substrate in the human hippocampus for linking successive events. Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13):6046-51. Paz R, Gelbard-Sagiv H, Mukamel R, Harel M, Malach R, Fried I. PMID: 20231430.
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    78. New approaches to structural and functional imaging in focal epilepsy. Epilepsia. 2010 Feb; 51 Suppl 1:83-6. Engel J, Akhtari M, Bragin A, Fried I, Ogren JA, Staba RJ, Salamon N, Thompson PM. PMID: 20331726.
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    79. Epileptogenic temporal cavernous malformations: operative strategies and postoperative seizure outcomes. Seizure. 2010 Mar; 19(2):120-8. Upchurch K, Stern JM, Salamon N, Dewar S, Engel J, Vinters HV, Fried I. PMID: 20045354.
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    80. Human medial temporal lobe neurons respond preferentially to personally relevant images. Proc Natl Acad Sci U S A. 2009 Dec 15; 106(50):21329-34. Viskontas IV, Quiroga RQ, Fried I. PMID: 19955441.
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    81. Three-dimensional surface maps link local atrophy and fast ripples in human epileptic hippocampus. Ann Neurol. 2009 Dec; 66(6):783-91. Ogren JA, Wilson CL, Bragin A, Lin JJ, Salamon N, Dutton RA, Luders E, Fields TA, Fried I, Toga AW, Thompson PM, Engel J, Staba RJ. PMID: 20035513.
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    82. Neural "ignition": enhanced activation linked to perceptual awareness in human ventral stream visual cortex. Neuron. 2009 Nov 25; 64(4):562-74. Fisch L, Privman E, Ramot M, Harel M, Nir Y, Kipervasser S, Andelman F, Neufeld MY, Kramer U, Fried I, Malach R. PMID: 19945397.
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    83. Responses of human medial temporal lobe neurons are modulated by stimulus repetition. J Neurophysiol. 2010 Jan; 103(1):97-107. Pedreira C, Mormann F, Kraskov A, Cerf M, Fried I, Koch C, Quiroga RQ. PMID: 19864436.
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    84. An automatic measure for classifying clusters of suspected spikes into single cells versus multiunits. J Neural Eng. 2009 Oct; 6(5):056001. Tankus A, Yeshurun Y, Fried I. PMID: 19667458.
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    85. Explicit encoding of multimodal percepts by single neurons in the human brain. Curr Biol. 2009 Aug 11; 19(15):1308-13. Quian Quiroga R, Kraskov A, Koch C, Fried I. PMID: 19631538.
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    86. Encoding of speed and direction of movement in the human supplementary motor area. J Neurosurg. 2009 Jun; 110(6):1304-16. Tankus A, Yeshurun Y, Flash T, Fried I. PMID: 19231930.
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    87. Source localization of temporal lobe epilepsy using PCA-LORETA analysis on ictal EEG recordings. J Clin Neurophysiol. 2009 Apr; 26(2):109-16. Stern Y, Neufeld MY, Kipervasser S, Zilberstein A, Fried I, Teicher M, Adi-Japha E. PMID: 19279504.
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    88. Correlation between BOLD fMRI and theta-band local field potentials in the human hippocampal area. J Neurophysiol. 2009 May; 101(5):2668-78. Ekstrom A, Suthana N, Millett D, Fried I, Bookheimer S. PMID: 19244353.
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    89. Assessment and surgical outcomes for mild type I and severe type II cortical dysplasia: a critical review and the UCLA experience. Epilepsia. 2009 Jun; 50(6):1310-35. Lerner JT, Salamon N, Hauptman JS, Velasco TR, Hemb M, Wu JY, Sankar R, Donald Shields W, Engel J, Fried I, Cepeda C, Andre VM, Levine MS, Miyata H, Yong WH, Vinters HV, Mathern GW. PMID: 19175385.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    90. Internally generated reactivation of single neurons in human hippocampus during free recall. Science. 2008 Oct 03; 322(5898):96-101. Gelbard-Sagiv H, Mukamel R, Harel M, Malach R, Fried I. PMID: 18772395.
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    91. Latency and selectivity of single neurons indicate hierarchical processing in the human medial temporal lobe. J Neurosci. 2008 Sep 03; 28(36):8865-72. Mormann F, Kornblith S, Quiroga RQ, Kraskov A, Cerf M, Fried I, Koch C. PMID: 18768680.
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    92. Interhemispheric correlations of slow spontaneous neuronal fluctuations revealed in human sensory cortex. Nat Neurosci. 2008 Sep; 11(9):1100-8. Nir Y, Mukamel R, Dinstein I, Privman E, Harel M, Fisch L, Gelbard-Sagiv H, Kipervasser S, Andelman F, Neufeld MY, Kramer U, Arieli A, Fried I, Malach R. PMID: 19160509.
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    93. High-resolution depth electrode localization and imaging in patients with pharmacologically intractable epilepsy. J Neurosurg. 2008 Apr; 108(4):812-5. Ekstrom A, Suthana N, Behnke E, Salamon N, Bookheimer S, Fried I. PMID: 18377264.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    94. Coupling between neuronal firing rate, gamma LFP, and BOLD fMRI is related to interneuronal correlations. Curr Biol. 2007 Aug 07; 17(15):1275-85. Nir Y, Fisch L, Mukamel R, Gelbard-Sagiv H, Arieli A, Fried I, Malach R. PMID: 17686438.
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    95. Increased fast ripple to ripple ratios correlate with reduced hippocampal volumes and neuron loss in temporal lobe epilepsy patients. Epilepsia. 2007 Nov; 48(11):2130-8. Staba RJ, Frighetto L, Behnke EJ, Mathern GW, Fields T, Bragin A, Ogren J, Fried I, Wilson CL, Engel J. PMID: 17662059.
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    96. Enhanced category tuning revealed by intracranial electroencephalograms in high-order human visual areas. J Neurosci. 2007 Jun 06; 27(23):6234-42. Privman E, Nir Y, Kramer U, Kipervasser S, Andelman F, Neufeld MY, Mukamel R, Yeshurun Y, Fried I, Malach R. PMID: 17553996.
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    97. Brain oscillations control timing of single-neuron activity in humans. J Neurosci. 2007 Apr 04; 27(14):3839-44. Jacobs J, Kahana MJ, Ekstrom AD, Fried I. PMID: 17409248.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansCells
    98. Local field potentials and spikes in the human medial temporal lobe are selective to image category. J Cogn Neurosci. 2007 Mar; 19(3):479-92. Kraskov A, Quiroga RQ, Reddy L, Fried I, Koch C. PMID: 17335396.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    99. Characterizing interneuron and pyramidal cells in the human medial temporal lobe in vivo using extracellular recordings. Hippocampus. 2007; 17(1):49-57. Viskontas IV, Ekstrom AD, Wilson CL, Fried I. PMID: 17143903.
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    100. Contrasting roles of neural firing rate and local field potentials in human memory. Hippocampus. 2007; 17(8):606-17. Ekstrom A, Viskontas I, Kahana M, Jacobs J, Upchurch K, Bookheimer S, Fried I. PMID: 17546683.
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    101. A single-neuron correlate of change detection and change blindness in the human medial temporal lobe. Curr Biol. 2006 Oct 24; 16(20):2066-72. Reddy L, Quiroga RQ, Wilken P, Koch C, Fried I. PMID: 17055988.
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    102. Sparse representation in the human medial temporal lobe. J Neurosci. 2006 Oct 04; 26(40):10232-4. Waydo S, Kraskov A, Quian Quiroga R, Fried I, Koch C. PMID: 17021178.
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    103. Differences in mnemonic processing by neurons in the human hippocampus and parahippocampal regions. J Cogn Neurosci. 2006 Oct; 18(10):1654-62. Viskontas IV, Knowlton BJ, Steinmetz PN, Fried I. PMID: 17014370.
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    104. Hippocampal memory function as reflected by the intracarotid sodium methohexital Wada test. Epilepsy Behav. 2006 Dec; 9(4):579-86. Andelman F, Kipervasser S, Reider-Groswasser II, Fried I, Neufeld MY. PMID: 16938491.
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    105. Extracellular adenosine in the human brain during sleep and sleep deprivation: an in vivo microdialysis study. Sleep. 2006 Apr; 29(4):455-61. Zeitzer JM, Morales-Villagran A, Maidment NT, Behnke EJ, Ackerson LC, Lopez-Rodriguez F, Fried I, Engel J, Wilson CL. PMID: 16676778.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    106. Low frequency electrical stimulation through subdural electrodes in a case of refractory status epilepticus. Clin Neurophysiol. 2006 Apr; 117(4):781-8. Schrader LM, Stern JM, Wilson CL, Fields TA, Salamon N, Nuwer MR, Vespa PM, Fried I. PMID: 16458067.
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    107. Predictive value of Wada memory scores on postoperative learning and memory abilities in patients with intractable epilepsy. J Neurosurg. 2006 Jan; 104(1):20-6. Andelman F, Kipervasser S, Neufeld MY, Kramer U, Fried I. PMID: 16509143.
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    108. Coupling between neuronal firing, field potentials, and FMRI in human auditory cortex. Science. 2005 Aug 05; 309(5736):951-4. Mukamel R, Gelbard H, Arieli A, Hasson U, Fried I, Malach R. PMID: 16081741.
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    109. Human hippocampal theta activity during virtual navigation. Hippocampus. 2005; 15(7):881-9. Ekstrom AD, Caplan JB, Ho E, Shattuck K, Fried I, Kahana MJ. PMID: 16114040.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    110. Analysis of seizure onset on the basis of wideband EEG recordings. Epilepsia. 2005; 46 Suppl 5:59-63. Bragin A, Wilson CL, Fields T, Fried I, Engel J. PMID: 15987255.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    111. Invasive recordings from the human brain: clinical insights and beyond. Nat Rev Neurosci. 2005 Jan; 6(1):35-47. Engel AK, Moll CK, Fried I, Ojemann GA. PMID: 15611725.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    112. Consciousness and neurosurgery. Neurosurgery. 2004 Aug; 55(2):273-281; discussion 281-2. Crick F, Koch C, Kreiman G, Fried I. PMID: 15271233.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    113. The separation of Guatemalan craniopagus twins. Childs Nerv Syst. 2004 Aug; 20(8-9):593-600. Frazee J, Fried I, Kawamoto H, Lazareff J, Nieto J, Patel S, Urata M, van de Wiele B. PMID: 15258818.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    114. Lateralization of deficit in self-awareness of memory in patients with intractable epilepsy. Epilepsia. 2004 Jul; 45(7):826-33. Andelman F, Zuckerman-Feldhay E, Hoffien D, Fried I, Neufeld MY. PMID: 15230708.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    115. High-frequency oscillations recorded in human medial temporal lobe during sleep. Ann Neurol. 2004 Jul; 56(1):108-15. Staba RJ, Wilson CL, Bragin A, Jhung D, Fried I, Engel J. PMID: 15236407.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimals
    116. Unilateral hippocampal sclerosis with contralateral temporal scalp ictal onset. Epilepsia. 2004 Jul; 45(7):792-802. Mintzer S, Cendes F, Soss J, Andermann F, Engel J, Dubeau F, Olivier A, Fried I. PMID: 15230704.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    117. Effects of topiramate on memory performance on the intracarotid amobarbital (Wada) test. Epilepsy Behav. 2004 Apr; 5(2):197-203. Kipervasser S, Andelman F, Kramer U, Nagar S, Fried I, Neufeld MY. PMID: 15123021.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    118. Single-neuron activity in the human supplementary motor area underlying preparation for action. J Neurosurg. 2004 Feb; 100(2):250-9. Amador N, Fried I. PMID: 15086232.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    119. Delineating gray and white matter involvement in brain lesions: three-dimensional alignment of functional magnetic resonance and diffusion-tensor imaging. J Neurosurg. 2003 Dec; 99(6):1018-27. Hendler T, Pianka P, Sigal M, Kafri M, Ben-Bashat D, Constantini S, Graif M, Fried I, Assaf Y. PMID: 14705730.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    120. Cellular networks underlying human spatial navigation. Nature. 2003 Sep 11; 425(6954):184-8. Ekstrom AD, Kahana MJ, Caplan JB, Fields TA, Isham EA, Newman EL, Fried I. PMID: 12968182.
      View in: PubMed   Mentions: 297     Fields:    Translation:HumansCells
    121. Regional analyses of CNS microdialysate glucose and lactate in seizure patients. Epilepsia. 2002 Nov; 43(11):1360-71. Cornford EM, Shamsa K, Zeitzer JM, Enriquez CM, Wilson CL, Behnke EJ, Fried I, Engel J. PMID: 12423386.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    122. Interictal high-frequency oscillations (80-500 Hz) in the human epileptic brain: entorhinal cortex. Ann Neurol. 2002 Oct; 52(4):407-15. Bragin A, Wilson CL, Staba RJ, Reddick M, Fried I, Engel J. PMID: 12325068.
      View in: PubMed   Mentions: 92     Fields:    Translation:Humans
    123. Quantitative analysis of high-frequency oscillations (80-500 Hz) recorded in human epileptic hippocampus and entorhinal cortex. J Neurophysiol. 2002 Oct; 88(4):1743-52. Staba RJ, Wilson CL, Bragin A, Fried I, Engel J. PMID: 12364503.
      View in: PubMed   Mentions: 167     Fields:    Translation:Humans
    124. Sleep states differentiate single neuron activity recorded from human epileptic hippocampus, entorhinal cortex, and subiculum. J Neurosci. 2002 Jul 01; 22(13):5694-704. Staba RJ, Wilson CL, Bragin A, Fried I, Engel J. PMID: 12097521.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    125. Inhibitory and excitatory responses of single neurons in the human medial temporal lobe during recognition of faces and objects. Cereb Cortex. 2002 Jun; 12(6):575-84. Fried I, Cameron KA, Yashar S, Fong R, Morrow JW. PMID: 12003857.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    126. Single-neuron correlates of subjective vision in the human medial temporal lobe. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8378-83. Kreiman G, Fried I, Koch C. PMID: 12034865.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    127. The role of the amygdala in signaling prospective outcome of choice. Neuron. 2002 Mar 14; 33(6):983-94. Kahn I, Yeshurun Y, Rotshtein P, Fried I, Ben-Bashat D, Hendler T. PMID: 11906703.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    128. Single neuron burst firing in the human hippocampus during sleep. Hippocampus. 2002; 12(6):724-34. Staba RJ, Wilson CL, Fried I, Engel J. PMID: 12542225.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    129. Cerebral microdialysis combined with single-neuron and electroencephalographic recording in neurosurgical patients. Technical note. J Neurosurg. 1999 Oct; 91(4):697-705. Fried I, Wilson CL, Maidment NT, Engel J, Behnke E, Fields TA, MacDonald KA, Morrow JW, Ackerson L. PMID: 10507396.
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