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Distinct Patterns of Gene Expression Changes in the Colon and Striatum of Young Mice Overexpressing Alpha-Synuclein Support Parkinson's Disease as a Multi-System Process. J Parkinsons Dis. 2023; 13(7):1127-1147.
Videlock EJ, Hatami A, Zhu C, Kawaguchi R, Chen H, Khan T, Yehya AHS, Stiles L, Joshi S, Hoffman JM, Law KM, Rankin CR, Chang L, Maidment NT, John V, Geschwind DH, Pothoulakis C. PMID: 37638450; PMCID: PMC10657720.
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Translation:
HumansAnimals
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The proSAAS Chaperone Provides Neuroprotection and Attenuates Transsynaptic α-Synuclein Spread in Rodent Models of Parkinson's Disease. J Parkinsons Dis. 2022; 12(5):1463-1478.
Lindberg I, Shu Z, Lam H, Helwig M, Yucer N, Laperle A, Svendsen CN, Di Monte DA, Maidment NT. PMID: 35527562.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Hypocretin/Orexin Interactions with Norepinephrine Contribute to the Opiate Withdrawal Syndrome. J Neurosci. 2022 01 12; 42(2):255-263.
McGregor R, Wu MF, Holmes B, Lam HA, Maidment NT, Gera J, Yamanaka A, Siegel JM. PMID: 34853083; PMCID: PMC8802943.
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PubMed Mentions:
7 Fields:
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Reward-predictive cues elicit excessive reward seeking in adolescent rats. Dev Cogn Neurosci. 2020 10; 45:100838.
Marshall AT, Munson CN, Maidment NT, Ostlund SB. PMID: 32846387; PMCID: PMC7451619.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery. Lab Chip. 2020 04 21; 20(8):1390-1397.
Wang B, Wen X, Cao Y, Huang S, Lam HA, Liu TL, Chung PS, Monbouquette HG, Chiou PY, Maidment NT. PMID: 32211718; PMCID: PMC7192313.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates. Nat Med. 2020 02; 26(2):289-299.
Laperle AH, Sances S, Yucer N, Dardov VJ, Garcia VJ, Ho R, Fulton AN, Jones MR, Roxas KM, Avalos P, West D, Banuelos MG, Shu Z, Murali R, Maidment NT, Van Eyk JE, Tagliati M, Svendsen CN. PMID: 31988461.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Flexible, multifunctional neural probe with liquid metal enabled, ultra-large tunable stiffness for deep-brain chemical sensing and agent delivery. Biosens Bioelectron. 2019 Apr 15; 131:37-45.
Wen X, Wang B, Huang S, Liu TL, Lee MS, Chung PS, Chow YT, Huang IW, Monbouquette HG, Maidment NT, Chiou PY. PMID: 30818131; PMCID: PMC6602555.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimals
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Junk Food Exposure Disrupts Selection of Food-Seeking Actions in Rats. Front Psychiatry. 2018; 9:350.
Kosheleff AR, Araki J, Tsan L, Chen G, Murphy NP, Maidment NT, Ostlund SB. PMID: 30166974; PMCID: PMC6106797.
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PubMed Mentions:
9
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Pattern of access determines influence of junk food diet on cue sensitivity and palatability. Appetite. 2018 04 01; 123:135-145.
Kosheleff AR, Araki J, Hsueh J, Le A, Quizon K, Ostlund SB, Maidment NT, Murphy NP. PMID: 29248689; PMCID: PMC5817006.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Sex-specific enhancement of palatability-driven feeding in adolescent rats. PLoS One. 2017; 12(7):e0180907.
Marshall AT, Liu AT, Murphy NP, Maidment NT, Ostlund SB. PMID: 28708901; PMCID: PMC5510835.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice. Neurobiol Aging. 2017 03; 51:54-66.
Richter F, Gabby L, McDowell KA, Mulligan CK, De La Rosa K, Sioshansi PC, Mortazavi F, Cely I, Ackerson LC, Tsan L, Murphy NP, Maidment NT, Chesselet MF. PMID: 28038352; PMCID: PMC5292275.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Modulation of cue-triggered reward seeking by cholinergic signaling in the dorsomedial striatum. Eur J Neurosci. 2017 02; 45(3):358-364.
Ostlund SB, Liu AT, Wassum KM, Maidment NT. PMID: 27813263; PMCID: PMC5293608.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Parsing the hedonic and motivational influences of nociceptin on feeding using licking microstructure analysis in mice. Behav Pharmacol. 2016 09; 27(6):516-27.
Mendez IA, Maidment NT, Murphy NP. PMID: 27100061; PMCID: PMC4965319.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity. Proc Natl Acad Sci U S A. 2016 08 09; 113(32):E4708-15.
Jarvela TS, Lam HA, Helwig M, Lorenzen N, Otzen DE, McLean PJ, Maidment NT, Lindberg I. PMID: 27457957; PMCID: PMC4987805.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Involvement of Endogenous Enkephalins and β-Endorphin in Feeding and Diet-Induced Obesity. Neuropsychopharmacology. 2015 Aug; 40(9):2103-12.
Mendez IA, Ostlund SB, Maidment NT, Murphy NP. PMID: 25754760; PMCID: PMC4613613.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism. Sci Transl Med. 2015 Jan 21; 7(271):271ra8.
Peñagarikano O, Lázaro MT, Lu XH, Gordon A, Dong H, Lam HA, Peles E, Maidment NT, Murphy NP, Yang XW, Golshani P, Geschwind DH. PMID: 25609168; PMCID: PMC4498455.
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PubMed Mentions:
166 Fields:
Translation:
HumansAnimalsCells
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Inflated reward value in early opiate withdrawal. Addict Biol. 2016 Mar; 21(2):221-33.
Wassum KM, Greenfield VY, Linker KE, Maidment NT, Ostlund SB. PMID: 25081350; PMCID: PMC4312551.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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The redistribution of Drosophila vesicular monoamine transporter mutants from synaptic vesicles to large dense-core vesicles impairs amine-dependent behaviors. J Neurosci. 2014 May 14; 34(20):6924-37.
Grygoruk A, Chen A, Martin CA, Lawal HO, Fei H, Gutierrez G, Biedermann T, Najibi R, Hadi R, Chouhan AK, Murphy NP, Schweizer FE, Macleod GT, Maidment NT, Krantz DE. PMID: 24828646; PMCID: PMC4019805.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Phasic mesolimbic dopamine signaling encodes the facilitation of incentive motivation produced by repeated cocaine exposure. Neuropsychopharmacology. 2014 Sep; 39(10):2441-9.
Ostlund SB, LeBlanc KH, Kosheleff AR, Wassum KM, Maidment NT. PMID: 24804846; PMCID: PMC4138756.
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PubMed Mentions:
45 Fields:
Translation:
Animals
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Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward. Nat Neurosci. 2014 Feb; 17(2):254-61.
Cui Y, Ostlund SB, James AS, Park CS, Ge W, Roberts KW, Mittal N, Murphy NP, Cepeda C, Kieffer BL, Levine MS, Jentsch JD, Walwyn WM, Sun YE, Evans CJ, Maidment NT, Yang XW. PMID: 24413699; PMCID: PMC4008330.
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PubMed Mentions:
70 Fields:
Translation:
AnimalsCells
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Differential effects of systemic cholinergic receptor blockade on Pavlovian incentive motivation and goal-directed action selection. Neuropsychopharmacology. 2014 May; 39(6):1490-7.
Ostlund SB, Kosheleff AR, Maidment NT. PMID: 24370780; PMCID: PMC3988553.
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PubMed Mentions:
8 Fields:
Translation:
Animals
-
Impact of repeated intravenous cocaine administration on incentive motivation depends on mode of drug delivery. Addict Biol. 2014 Nov; 19(6):965-71.
LeBlanc KH, Maidment NT, Ostlund SB. PMID: 23639056; PMCID: PMC3903657.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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Repeated cocaine exposure facilitates the expression of incentive motivation and induces habitual control in rats. PLoS One. 2013; 8(4):e61355.
LeBlanc KH, Maidment NT, Ostlund SB. PMID: 23646106; PMCID: PMC3640016.
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PubMed Mentions:
54 Fields:
Translation:
Animals
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Decreased consumption of sweet fluids in μ opioid receptor knockout mice: a microstructural analysis of licking behavior. Psychopharmacology (Berl). 2013 Sep; 229(1):105-13.
Ostlund SB, Kosheleff A, Maidment NT, Murphy NP. PMID: 23568577; PMCID: PMC3742650.
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PubMed Mentions:
24 Fields:
Translation:
Animals
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Phasic mesolimbic dopamine release tracks reward seeking during expression of Pavlovian-to-instrumental transfer. Biol Psychiatry. 2013 Apr 15; 73(8):747-55.
Wassum KM, Ostlund SB, Loewinger GC, Maidment NT. PMID: 23374641; PMCID: PMC3615104.
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PubMed Mentions:
46 Fields:
Translation:
Animals
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Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction. Nat Commun. 2013; 4:1547.
Blouin AM, Fried I, Wilson CL, Staba RJ, Behnke EJ, Lam HA, Maidment NT, Karlsson KÆ, Lapierre JL, Siegel JM. PMID: 23462990; PMCID: PMC3595130.
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PubMed Mentions:
107 Fields:
Translation:
HumansAnimals
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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease. Proc Natl Acad Sci U S A. 2013 Jan 08; 110(2):636-41.
Fitzmaurice AG, Rhodes SL, Lulla A, Murphy NP, Lam HA, O'Donnell KC, Barnhill L, Casida JE, Cockburn M, Sagasti A, Stahl MC, Maidment NT, Ritz B, Bronstein JM. PMID: 23267077; PMCID: PMC3545765.
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PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
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Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression. Mol Psychiatry. 2014 Feb; 19(2):235-42.
Lawal HO, Terrell A, Lam HA, Djapri C, Jang J, Hadi R, Roberts L, Shahi V, Chou MT, Biedermann T, Huang B, Lawless GM, Maidment NT, Krantz DE. PMID: 23229049; PMCID: PMC3610854.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Electrochemically deposited iridium oxide reference electrode integrated with an electroenzymatic glutamate sensor on a multi-electrode array microprobe. Biosens Bioelectron. 2013 Apr 15; 42:256-60.
Tolosa VM, Wassum KM, Maidment NT, Monbouquette HG. PMID: 23208095.
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PubMed Mentions:
18 Fields:
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Dispensable, redundant, complementary, and cooperative roles of dopamine, octopamine, and serotonin in Drosophila melanogaster. Genetics. 2013 Jan; 193(1):159-76.
Chen A, Ng F, Lebestky T, Grygoruk A, Djapri C, Lawal HO, Zaveri HA, Mehanzel F, Najibi R, Seidman G, Murphy NP, Kelly RL, Ackerson LC, Maidment NT, Jackson FR, Krantz DE. PMID: 23086220; PMCID: PMC3527243.
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PubMed Mentions:
30 Fields:
Translation:
Animals
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Pavlovian-to-instrumental transfer in cocaine seeking rats. Behav Neurosci. 2012 Oct; 126(5):681-9.
LeBlanc KH, Ostlund SB, Maidment NT. PMID: 22866668; PMCID: PMC3496413.
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PubMed Mentions:
38 Fields:
Translation:
Animals
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Relative response cost determines the sensitivity of instrumental reward seeking to dopamine receptor blockade. Neuropsychopharmacology. 2012 Nov; 37(12):2653-60.
Ostlund SB, Kosheleff AR, Maidment NT. PMID: 22805602; PMCID: PMC3473331.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Ghrelin prevents levodopa-induced inhibition of gastric emptying and increases circulating levodopa in fasted rats. Neurogastroenterol Motil. 2012 May; 24(5):e235-45.
Wang L, Murphy NP, Stengel A, Goebel-Stengel M, St Pierre DH, Maidment NT, Taché Y. PMID: 22443313; PMCID: PMC3345891.
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PubMed Mentions:
12 Fields:
Translation:
Animals
-
Transient extracellular glutamate events in the basolateral amygdala track reward-seeking actions. J Neurosci. 2012 Feb 22; 32(8):2734-46.
Wassum KM, Tolosa VM, Tseng TC, Balleine BW, Monbouquette HG, Maidment NT. PMID: 22357857; PMCID: PMC3548241.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Phasic mesolimbic dopamine signaling precedes and predicts performance of a self-initiated action sequence task. Biol Psychiatry. 2012 May 15; 71(10):846-54.
Wassum KM, Ostlund SB, Maidment NT. PMID: 22305286; PMCID: PMC3471807.
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PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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μ- and δ-opioid-related processes in the accumbens core and shell differentially mediate the influence of reward-guided and stimulus-guided decisions on choice. J Neurosci. 2012 Feb 01; 32(5):1875-83.
Laurent V, Leung B, Maidment N, Balleine BW. PMID: 22302826; PMCID: PMC3742880.
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PubMed Mentions:
39 Fields:
Translation:
Animals
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Dopamine receptor blockade attenuates the general incentive motivational effects of noncontingently delivered rewards and reward-paired cues without affecting their ability to bias action selection. Neuropsychopharmacology. 2012 Jan; 37(2):508-19.
Ostlund SB, Maidment NT. PMID: 21918507; PMCID: PMC3242312.
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PubMed Mentions:
32 Fields:
Translation:
Animals
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Presynaptic control of rapid estrogen fluctuations in the songbird auditory forebrain. J Neurosci. 2011 Jul 06; 31(27):10034-8.
Remage-Healey L, Dong S, Maidment NT, Schlinger BA. PMID: 21734295; PMCID: PMC3144393.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Differential dependence of Pavlovian incentive motivation and instrumental incentive learning processes on dopamine signaling. Learn Mem. 2011; 18(7):475-83.
Wassum KM, Ostlund SB, Balleine BW, Maidment NT. PMID: 21693635; PMCID: PMC3125614.
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PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
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Role of the hypocretin (orexin) receptor 2 (Hcrt-r2) in the regulation of hypocretin level and cataplexy. J Neurosci. 2011 Apr 27; 31(17):6305-10.
Wu MF, Nienhuis R, Maidment N, Lam HA, Siegel JM. PMID: 21525270; PMCID: PMC3097029.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2. Mol Pain. 2011 Apr 12; 7:24.
Lam H, Maga M, Pradhan A, Evans CJ, Maidment NT, Hales TG, Walwyn W. PMID: 21486473; PMCID: PMC3090352.
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PubMed Mentions:
18 Fields:
Translation:
Animals
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Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein. J Neurosci Res. 2011 Jul; 89(7):1091-102.
Lam HA, Wu N, Cely I, Kelly RL, Hean S, Richter F, Magen I, Cepeda C, Ackerson LC, Walwyn W, Masliah E, Chesselet MF, Levine MS, Maidment NT. PMID: 21488084; PMCID: PMC4755488.
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PubMed Mentions:
85 Fields:
Translation:
HumansAnimalsCells
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Micro-opioid receptor activation in the basolateral amygdala mediates the learning of increases but not decreases in the incentive value of a food reward. J Neurosci. 2011 Feb 02; 31(5):1591-9.
Wassum KM, Cely IC, Balleine BW, Maidment NT. PMID: 21289167; PMCID: PMC3081716.
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PubMed Mentions:
35 Fields:
Translation:
Animals
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Extracellular dopamine levels in striatal subregions track shifts in motivation and response cost during instrumental conditioning. J Neurosci. 2011 Jan 05; 31(1):200-7.
Ostlund SB, Wassum KM, Murphy NP, Balleine BW, Maidment NT. PMID: 21209205; PMCID: PMC3078720.
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PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
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Alcohol-Paired Contextual Cues Produce an Immediate and Selective Loss of Goal-directed Action in Rats. Front Integr Neurosci. 2010; 4.
Ostlund SB, Maidment NT, Balleine BW. PMID: 20725634; PMCID: PMC2917216.
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PubMed Mentions:
27
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Mutation of the Drosophila vesicular GABA transporter disrupts visual figure detection. J Exp Biol. 2010 May; 213(Pt 10):1717-30.
Fei H, Chow DM, Chen A, Romero-Calderón R, Ong WS, Ackerson LC, Maidment NT, Simpson JH, Frye MA, Krantz DE. PMID: 20435823; PMCID: PMC2861964.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Disruption of endogenous opioid activity during instrumental learning enhances habit acquisition. Neuroscience. 2009 Oct 20; 163(3):770-80.
Wassum KM, Cely IC, Maidment NT, Balleine BW. PMID: 19619616; PMCID: PMC3065789.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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Distinct opioid circuits determine the palatability and the desirability of rewarding events. Proc Natl Acad Sci U S A. 2009 Jul 28; 106(30):12512-7.
Wassum KM, Ostlund SB, Maidment NT, Balleine BW. PMID: 19597155; PMCID: PMC2718390.
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PubMed Mentions:
79 Fields:
Translation:
Animals
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Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. J Neurosci. 2009 Feb 18; 29(7):1962-76.
Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. PMID: 19228951; PMCID: PMC2803056.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Drosophila vesicular monoamine transporter mutants can adapt to reduced or eliminated vesicular stores of dopamine and serotonin. Genetics. 2009 Feb; 181(2):525-41.
Simon AF, Daniels R, Romero-Calderón R, Grygoruk A, Chang HY, Najibi R, Shamouelian D, Salazar E, Solomon M, Ackerson LC, Maidment NT, Diantonio A, Krantz DE. PMID: 19033154; PMCID: PMC2644945.
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PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system. PLoS Genet. 2008 Nov; 4(11):e1000245.
Romero-Calderón R, Uhlenbrock G, Borycz J, Simon AF, Grygoruk A, Yee SK, Shyer A, Ackerson LC, Maidment NT, Meinertzhagen IA, Hovemann BT, Krantz DE. PMID: 18989452; PMCID: PMC2570955.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Forebrain steroid levels fluctuate rapidly during social interactions. Nat Neurosci. 2008 Nov; 11(11):1327-34.
Remage-Healey L, Maidment NT, Schlinger BA. PMID: 18820691; PMCID: PMC2577388.
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PubMed Mentions:
179 Fields:
Translation:
Animals
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Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome. J Biol Chem. 2008 Dec 12; 283(50):34696-703.
Chou AP, Maidment N, Klintenberg R, Casida JE, Li S, Fitzmaurice AG, Fernagut PO, Mortazavi F, Chesselet MF, Bronstein JM. PMID: 18818210; PMCID: PMC2596383.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Silicon Wafer-Based Platinum Microelectrode Array Biosensor for Near Real-Time Measurement of Glutamate in Vivo. Sensors (Basel). 2008; 8(8):5023-5036.
Wassum KM, Tolosa VM, Wang J, Walker E, Monbouquette HG, Maidment NT. PMID: 19543440; PMCID: PMC2699285.
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PubMed Mentions:
46 Fields:
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Enkephalin release promotes homeostatic increases in constitutively active mu opioid receptors during morphine withdrawal. Neuroscience. 2007 Nov 09; 149(3):642-9.
Shoblock JR, Maidment NT. PMID: 17905519.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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Selective detection of extracellular glutamate in brain tissue using microelectrode arrays coated with over-oxidized polypyrrole. Analyst. 2007 Nov; 132(11):1107-11.
Walker E, Wang J, Hamdi N, Monbouquette HG, Maidment NT. PMID: 17955144.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Activation of nigral and pallidal dopamine D1-like receptors modulates basal ganglia outflow in monkeys. J Neurophysiol. 2007 Sep; 98(3):1489-500.
Kliem MA, Maidment NT, Ackerson LC, Chen S, Smith Y, Wichmann T. PMID: 17634344.
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PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
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A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J Neurosci. 2007 Jan 31; 27(5):981-92.
Sang TK, Chang HY, Lawless GM, Ratnaparkhi A, Mee L, Ackerson LC, Maidment NT, Krantz DE, Jackson GR. PMID: 17267552; PMCID: PMC6673194.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Mu opioid receptor-effector coupling and trafficking in dorsal root ganglia neurons. Neuroscience. 2006 Oct 13; 142(2):493-503.
Walwyn WM, Wei W, Xie CW, Chiu K, Kieffer BL, Evans CJ, Maidment NT. PMID: 16887280.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Extracellular adenosine in the human brain during sleep and sleep deprivation: an in vivo microdialysis study. Sleep. 2006 Apr; 29(4):455-61.
Zeitzer JM, Morales-Villagran A, Maidment NT, Behnke EJ, Ackerson LC, Lopez-Rodriguez F, Fried I, Engel J, Wilson CL. PMID: 16676778.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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HSV-1-mediated NGF delivery delays nociceptive deficits in a genetic model of diabetic neuropathy. Exp Neurol. 2006 Mar; 198(1):260-70.
Walwyn WM, Matsuka Y, Arai D, Bloom DC, Lam H, Tran C, Spigelman I, Maidment NT. PMID: 16427624.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Blockade of mGluR glutamate receptors in the subthalamic nucleus ameliorates motor asymmetry in an animal model of Parkinson's disease. Eur J Neurosci. 2006 Jan; 23(1):151-60.
Phillips JM, Lam HA, Ackerson LC, Maidment NT. PMID: 16420425.
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PubMed Mentions:
14 Fields:
Translation:
Animals
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Overexpression of the Drosophila vesicular monoamine transporter increases motor activity and courtship but decreases the behavioral response to cocaine. Mol Psychiatry. 2006 Jan; 11(1):99-113.
Chang HY, Grygoruk A, Brooks ES, Ackerson LC, Maidment NT, Bainton RJ, Krantz DE. PMID: 16189511.
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PubMed Mentions:
66 Fields:
Translation:
Animals
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Constitutively active micro opioid receptors mediate the enhanced conditioned aversive effect of naloxone in morphine-dependent mice. Neuropsychopharmacology. 2006 Jan; 31(1):171-7.
Shoblock JR, Maidment NT. PMID: 15956992.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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The effect of a systemically active ORL-1 agonist, Ro 64-6198, on the acquisition, expression, extinction, and reinstatement of morphine conditioned place preference. Neuropharmacology. 2005 Sep; 49(4):439-46.
Shoblock JR, Wichmann J, Maidment NT. PMID: 15919100.
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PubMed Mentions:
38 Fields:
Translation:
Animals
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Induction of delta opioid receptor function by up-regulation of membrane receptors in mouse primary afferent neurons. Mol Pharmacol. 2005 Dec; 68(6):1688-98.
Walwyn W, Maidment NT, Sanders M, Evans CJ, Kieffer BL, Hales TG. PMID: 16135785.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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GABAergic modulation of the activity of globus pallidus neurons in primates: in vivo analysis of the functions of GABA receptors and GABA transporters. J Neurophysiol. 2005 Aug; 94(2):990-1000.
Galvan A, Villalba RM, West SM, Maidment NT, Ackerson LC, Smith Y, Wichmann T. PMID: 15829599.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Endogenous enkephalins, not endorphins, modulate basal hedonic state in mice. Eur J Neurosci. 2005 Mar; 21(5):1379-84.
Skoubis PD, Lam HA, Shoblock J, Narayanan S, Maidment NT. PMID: 15813947.
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PubMed Mentions:
35 Fields:
Translation:
Animals
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Developmental changes in CSF hypocretin-1 (orexin-A) levels in normal and genetically narcoleptic Doberman pinschers. J Physiol. 2004 Oct 15; 560(Pt 2):587-92.
John J, Wu MF, Maidment NT, Lam HA, Boehmer LN, Patton M, Siegel JM. PMID: 15308685; PMCID: PMC1665256.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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N-myc regulates parkin expression. J Biol Chem. 2004 Jul 09; 279(28):28896-902.
West AB, Kapatos G, O'Farrell C, Gonzalez-de-Chavez F, Chiu K, Farrer MJ, Maidment NT. PMID: 15078880.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Genetics of parkin-linked disease. Hum Genet. 2004 Mar; 114(4):327-36.
West AB, Maidment NT. PMID: 14727181.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimals
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Functional coupling, desensitization and internalization of virally expressed mu opioid receptors in cultured dorsal root ganglion neurons from mu opioid receptor knockout mice. Neuroscience. 2004; 123(1):111-21.
Walwyn WM, Keith DE, Wei W, Tan AM, Xie CW, Evans CJ, Kieffer BL, Maidment NT. PMID: 14667446.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Nociceptin/orphanin FQ modulation of rat midbrain dopamine neurons in primary culture. Neuroscience. 2004; 127(4):929-40.
Murphy NP, Tan AM, Lam HA, Maidment NT. PMID: 15312905.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Endogenous opioids mediate basal hedonic tone independent of dopamine D-1 or D-2 receptor activation. Neuroscience. 2004; 124(1):241-6.
Narayanan S, Lam H, Christian L, Levine MS, Grandy D, Rubinstein M, Maidment NT. PMID: 14960355.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Buprenorphine-induced antinociception is mediated by mu-opioid receptors and compromised by concomitant activation of opioid receptor-like receptors. J Neurosci. 2003 Nov 12; 23(32):10331-7.
Lutfy K, Eitan S, Bryant CD, Yang YC, Saliminejad N, Walwyn W, Kieffer BL, Takeshima H, Carroll FI, Maidment NT, Evans CJ. PMID: 14614092; PMCID: PMC6741014.
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PubMed Mentions:
98 Fields:
Translation:
HumansAnimalsCells
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Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J Biol Chem. 2003 Oct 31; 278(44):43628-35.
Goldberg MS, Fleming SM, Palacino JJ, Cepeda C, Lam HA, Bhatnagar A, Meloni EG, Wu N, Ackerson LC, Klapstein GJ, Gajendiran M, Roth BL, Chesselet MF, Maidment NT, Levine MS, Shen J. PMID: 12930822.
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PubMed Mentions:
362 Fields:
Translation:
AnimalsCells
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Total sleep deprivation increases extracellular serotonin in the rat hippocampus. Neuroscience. 2003; 121(2):523-30.
Lopez-Rodriguez F, Wilson CL, Maidment NT, Poland RE, Engel J. PMID: 14522011.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Blockade of ventral pallidal opioid receptors induces a conditioned place aversion and attenuates acquisition of cocaine place preference in the rat. Neuroscience. 2003; 119(1):241-9.
Skoubis PD, Maidment NT. PMID: 12763085.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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Heroin-induced locomotion and mesolimbic dopamine release is unchanged in mice lacking the ORL.1 receptor gene. Brain Res. 2002 Oct 25; 953(1-2):276-80.
Murphy NP, Lam HA, Chen Z, Pintar JE, Maidment NT. PMID: 12384262.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats. Psychopharmacology (Berl). 2002 Nov; 164(2):168-76.
Lutfy K, Khaliq I, Carroll FI, Maidment NT. PMID: 12404079; PMCID: PMC2268895.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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Rat ventral midbrain dopamine neurons express the orphanin FQ/nociceptin receptor ORL-1. Neuroreport. 2002 Jul 02; 13(9):1137-40.
Maidment NT, Chen Y, Tan AM, Murphy NP, Leslie FM. PMID: 12151756.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Release of hypocretin (orexin) during waking and sleep states. J Neurosci. 2002 Jul 01; 22(13):5282-6.
Kiyashchenko LI, Mileykovskiy BY, Maidment N, Lam HA, Wu MF, John J, Peever J, Siegel JM. PMID: 12097478; PMCID: PMC6758234.
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PubMed Mentions:
139 Fields:
Translation:
Animals
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Sensitization does not develop to cocaine-induced potentiation of the antinociceptive effect of morphine. Brain Res Bull. 2002 May; 58(1):7-12.
Lutfy K, Maidment NT. PMID: 12121806.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Sensitization to cocaine after a single intra-cerebral injection of orphanin FQ/nociceptin. Behav Brain Res. 2002 Apr 01; 131(1-2):97-103.
Narayanan S, Lutfy K, Maidment N. PMID: 11844576.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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A comparison of morphine-induced locomotor activity and mesolimbic dopamine release in C57BL6, 129Sv and DBA2 mice. J Neurochem. 2001 Nov; 79(3):626-35.
Murphy NP, Lam HA, Maidment NT. PMID: 11701766.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Orphanin FQ/nociceptin attenuates the development of morphine tolerance in rats. Br J Pharmacol. 2001 Oct; 134(3):529-34.
Lutfy K, Hossain SM, Khaliq I, Maidment NT. PMID: 11588106; PMCID: PMC1572978.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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Orphanin FQ/nociceptin attenuates motor stimulation and changes in nucleus accumbens extracellular dopamine induced by cocaine in rats. Psychopharmacology (Berl). 2001 Feb; 154(1):1-7.
Lutfy K, Do T, Maidment NT. PMID: 11291998; PMCID: PMC2288655.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Increased dopamine release in the human amygdala during performance of cognitive tasks. Nat Neurosci. 2001 Feb; 4(2):201-6.
Fried I, Wilson CL, Morrow JW, Cameron KA, Behnke ED, Ackerson LC, Maidment NT. PMID: 11175882.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Blockade of mu-opioid receptors reveals the hyperalgesic effect of orphanin FQ/nociceptin in the rat hot plate test. Br J Pharmacol. 2000 Dec; 131(8):1684-8.
Lutfy K, Maidment NT. PMID: 11139447; PMCID: PMC1572505.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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Inflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivo. Brain Res. 2000 Jul 21; 871(2):181-91.
Neubert JK, Maidment NT, Matsuka Y, Adelson DW, Kruger L, Spigelman I. PMID: 10899285.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Opioid peptide systems following a subconvulsant dose of pentylenetetrazol in rats. Epilepsy Res. 1999 Nov; 37(2):141-50.
Rocha L, Cano A, Cruz C, Omaña-Zapata I, Villalobos R, Maidment NT. PMID: 10510980.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Cerebral microdialysis combined with single-neuron and electroencephalographic recording in neurosurgical patients. Technical note. J Neurosurg. 1999 Oct; 91(4):697-705.
Fried I, Wilson CL, Maidment NT, Engel J, Behnke E, Fields TA, MacDonald KA, Morrow JW, Ackerson L. PMID: 10507396.
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PubMed Mentions:
87 Fields:
Translation:
HumansCells
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Extracellular glutamate in the dorsal horn of the lumbar spinal cord in the freely moving rat during hindlimb stepping. Pharmacol Biochem Behav. 1999 Aug; 63(4):581-8.
Walwyn WM, Ta-Haung J, Ackerson L, Maidment NT, Edgerton VR. PMID: 10462186.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Orphanin FQ/nociceptin modulation of mesolimbic dopamine transmission determined by microdialysis. J Neurochem. 1999 Jul; 73(1):179-86.
Murphy NP, Maidment NT. PMID: 10386969.
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PubMed Mentions:
61 Fields:
Translation:
Animals
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Orphanin FQ/nociceptin blocks acquisition of morphine place preference. Brain Res. 1999 Jun 19; 832(1-2):168-70.
Murphy NP, Lee Y, Maidment NT. PMID: 10375664.
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PubMed Mentions:
65 Fields:
Translation:
Animals
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Orphanin FQ and behavioral sensitization to cocaine. Pharmacol Biochem Behav. 1999 Jun; 63(2):271-7.
Narayanan S, Maidment NT. PMID: 10371656.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Gabapentin modifies extracellular opioid peptide content in amygdala: a microdialysis study. Epilepsy Res. 1999 May; 35(1):13-20.
Rocha L, Ondarza-Rovira R, Maidment NT. PMID: 10232790.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Tolerance develops to the inhibitory effect of orphanin FQ on morphine-induced antinociception in the rat. Neuroreport. 1999 Jan 18; 10(1):103-6.
Lutfy K, Sharza SA, Maidment NT. PMID: 10094142.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Repeated heroin administration increases extracellular opioid peptide-like immunoreactivity in the globus pallidus/ventral pallidum of freely moving rats. Psychopharmacology (Berl). 1998 Oct; 139(3):251-4.
Olive MF, Maidment NT. PMID: 9784081.
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PubMed Mentions:
11 Fields:
Translation:
Animals
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Opioid regulation of pallidal enkephalin release: bimodal effects of locally administered mu and delta opioid agonists in freely moving rats. J Pharmacol Exp Ther. 1998 Jun; 285(3):1310-6.
Olive MF, Maidment NT. PMID: 9618438.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Dopaminergic and glutamatergic interactions in the expression of self-injurious behavior. Dev Neurosci. 1998; 20(2-3):180-7.
King BH, Cromwell HC, Lee HT, Behrstock SP, Schmanke T, Maidment NT. PMID: 9691192.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Presynaptic versus postsynaptic localization of mu and delta opioid receptors in dorsal and ventral striatopallidal pathways. J Neurosci. 1997 Oct 01; 17(19):7471-9.
Olive MF, Anton B, Micevych P, Evans CJ, Maidment NT. PMID: 9295393; PMCID: PMC6573463.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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Persistence of the releasable pool of CCK in the rat nucleus accumbens and caudate-putamen following lesions of the midbrain. Brain Res. 1997 Feb 07; 747(2):290-6.
Maidment NT, Villafranca NP. PMID: 9046004.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Amygdala kindling modifies extracellular opioid peptide content in rat hippocampus measured by microdialysis. J Neurochem. 1997 Feb; 68(2):616-24.
Rocha LL, Evans CJ, Maidment NT. PMID: 9003048.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Basal total opioid peptide release in the striatum of rats with cholestasis from bile duct resection: a study by the use of in vivo microdialysis. Life Sci. 1997; 61(12):1169-75.
Bergasa NV, Mohajer B, Maisonneuve IM, Ho A, Maidment NT, Olive F, Gunduz M, Kreek MJ. PMID: 9315507.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Pentylenetetrazol-induced kindling: early involvement of excitatory and inhibitory systems. Epilepsy Res. 1996 Dec; 26(1):105-13.
Rocha L, Briones M, Ackermann RF, Anton B, Maidment NT, Evans CJ, Engel J. PMID: 8985692.
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PubMed Mentions:
21 Fields:
Translation:
Animals
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Comparison of seizure related amino acid release in human epileptic hippocampus versus a chronic, kainate rat model of hippocampal epilepsy. Epilepsy Res. 1996 Dec; 26(1):245-54.
Wilson CL, Maidment NT, Shomer MH, Behnke EJ, Ackerson L, Fried I, Engel J. PMID: 8985704.
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PubMed Mentions:
37 Fields:
Translation:
HumansAnimals
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Intracerebroventricular orphanin FQ/nociceptin suppresses dopamine release in the nucleus accumbens of anaesthetized rats. Neuroscience. 1996 Nov; 75(1):1-4.
Murphy NP, Ly HT, Maidment NT. PMID: 8923516.
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PubMed Mentions:
55 Fields:
Translation:
Animals
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Expression of the lacZ reporter gene in the rat basal forebrain, hippocampus, and nigrostriatal pathway using a nonreplicating herpes simplex vector. Exp Neurol. 1996 May; 139(1):107-14.
Maidment NT, Tan AM, Bloom DC, Anton B, Feldman LT, Stevens JG. PMID: 8635556.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Pemoline produces ipsilateral turning behavior in unilateral 6-OHDA-lesioned rats. Prog Neuropsychopharmacol Biol Psychiatry. 1996 Apr; 20(3):503-14.
Cromwell HC, Witte EA, Crawford CA, Ly HT, Maidment NT, King BH. PMID: 8771605.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Opioid peptide release and mu-receptor binding during amygdala kindling in rats: regional discordances. Epilepsy Res Suppl. 1996; 12:215-28.
Rocha L, Maidment NT, Evans CJ, Ackermann RF, Engel J. PMID: 9302520.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Long-term expression of a reporter gene from latent herpes simplex virus in the rat hippocampus. Brain Res Mol Brain Res. 1995 Jul; 31(1-2):48-60.
Bloom DC, Maidment NT, Tan A, Dissette VB, Feldman LT, Stevens JG. PMID: 7476033.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Microdialysis reveals a morphine-induced increase in pallidal opioid peptide release. Neuroreport. 1995 May 30; 6(8):1093-6.
Olive MF, Bertolucci M, Evans CJ, Maidment NT. PMID: 7662884.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Microdialysis reveals changes in extracellular opioid peptide levels in the amygdala induced by amygdaloid kindling stimulation. Exp Neurol. 1994 Apr; 126(2):277-83.
Rocha L, Maidment NT, Evans CJ, Ackermann RF, Engel J. PMID: 7925825.
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PubMed Mentions:
1 Fields:
Translation:
Animals
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Amphetamine and other weak bases act to promote reverse transport of dopamine in ventral midbrain neurons. J Neurochem. 1993 Feb; 60(2):527-35.
Sulzer D, Maidment NT, Rayport S. PMID: 8419534.
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PubMed Mentions:
87 Fields:
Translation:
AnimalsCells
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Weak base model of amphetamine action. Ann N Y Acad Sci. 1992 Jun 28; 654:525-8.
Sulzer D, Pothos E, Sung HM, Maidment NT, Hoebel BG, Rayport S. PMID: 1632618.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Postmortem changes in rat brain extracellular opioid peptides revealed by microdialysis. J Neurochem. 1991 Jun; 56(6):1980-4.
Maidment NT, Siddall B, Rudolph VD, Evans CJ. PMID: 2027009.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Dual determination of extracellular cholecystokinin and neurotensin fragments in rat forebrain: microdialysis combined with a sequential multiple antigen radioimmunoassay. Neuroscience. 1991; 45(1):81-93.
Maidment NT, Siddall BJ, Rudolph VR, Erdelyi E, Evans CJ. PMID: 1754070.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Post-mortem dopamine dynamics assessed by voltammetry and microdialysis. Brain Res Bull. 1989 Oct-Nov; 23(4-5):323-7.
Gonzalez-Mora JL, Maidment NT, Guadalupe T, Mas M. PMID: 2590845.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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Microdialysis of extracellular endogenous opioid peptides from rat brain in vivo. Neuroscience. 1989; 33(3):549-57.
Maidment NT, Brumbaugh DR, Rudolph VD, Erdelyi E, Evans CJ. PMID: 2636708.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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Excitability properties of medial forebrain bundle axons of A9 and A10 dopamine cells. Brain Res. 1988 May 31; 450(1-2):86-93.
Yeomans JS, Maidment NT, Bunney BS. PMID: 3261193.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Acute administration of clozapine, thioridazine and metoclopramide increases extracellular DOPAC and decreases extracellular 5-HIAA, measured in the nucleus accumbens and striatum of the rat using in vivo voltammetry. Neuropharmacology. 1987 Feb-Mar; 26(2-3):187-93.
Maidment NT, Marsden CA. PMID: 2438582.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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In vivo voltammetric and behavioural evidence for somatodendritic autoreceptor control of mesolimbic dopamine neurones. Brain Res. 1985 Jul 15; 338(2):317-25.
Maidment NT, Marsden CA. PMID: 2992688.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Differential pulse voltammetry: simultaneous in vivo measurement of ascorbic acid, catechols and 5-hydroxyindoles in the rat striatum. Brain Res. 1984 Nov 19; 322(1):135-8.
Crespi F, Sharp T, Maidment NT, Marsden CA. PMID: 6083820.
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PubMed Mentions:
4 Fields:
Translation:
Animals