Mark Arthur Frye

Title(s)Professor, Integrative Biology And Physiology
SchoolCollege of Letters and Science
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    Other Positions
    Title(s)Professor, Neurobiology


    Collapse Research 
    Collapse Research Activities and Funding
    Olfactory neuromodulation of visual circuits and behavior
    NIH R01NS120984Apr 1, 2021 - Mar 31, 2026
    Role: Principal Investigator
    2019 Neuroethology Gordon Research Conference & Gordon Research Seminar
    NIH R13NS111917Apr 1, 2019 - Mar 31, 2020
    Role: Principal Investigator
    Neural circuits for visual feature detection
    NIH R01EY026031May 1, 2016 - Apr 30, 2021
    Role: Principal Investigator
    1H-MR Spectroscopy of Bipolar Depression Before and After Lamotrigine Treatment
    NIH R01MH079261Jul 1, 2009 - Sep 30, 2014
    Role: Principal Investigator
    Bipolar Disorder &Alcohol Abuse Comorbidity
    NIH K23MH001813Aug 16, 2001 - Jul 31, 2007
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Contributions of circadian clock genes to cell survival in fibroblast models of lithium-responsive bipolar disorder. Eur Neuropsychopharmacol. 2023 Apr 29; 74:1-14. Mishra HK, Wei H, Rohr KE, Ko I, Nievergelt CM, Maihofer AX, Shilling PD, Alda M, Berrettini WH, Brennand KJ, Calabrese JR, Coryell WH, Frye M, Gage F, Gershon E, McInnis MG, Nurnberger J, Oedegaard KJ, Zandi PP, Kelsoe JR, McCarthy MJ. PMID: 37126998.
      View in: PubMed   Mentions:    Fields:    
    2. Insulin resistance in bipolar disorder: A systematic review of illness course and clinical correlates. J Affect Disord. 2023 Apr 20. Miola A, Alvarez-Villalobos NA, Ruiz-Hernandez FG, De Filippis E, Veldic M, Prieto ML, Singh B, Sanchez Ruiz JA, Nunez NA, Resendez MG, Romo-Nava F, McElroy SL, Ozerdem A, Biernacka JM, Frye MA, Cuellar-Barboza AB. PMID: 37086806.
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    3. Columnar neurons support saccadic bar tracking in Drosophila. Elife. 2023 04 04; 12. Frighetto G, Frye MA. PMID: 37014060; PMCID: PMC10115446.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Proprioception gates visual object fixation in flying flies. Curr Biol. 2023 Apr 24; 33(8):1459-1471.e3. Rimniceanu M, Currea JP, Frye MA. PMID: 37001520; PMCID: PMC10133043.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    5. Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis. Mol Psychiatry. 2023 Mar 29. Niemsiri V, Rosenthal SB, Nievergelt CM, Maihofer AX, Marchetto MC, Santos R, Shekhtman T, Alliey-Rodriguez N, Anand A, Balaraman Y, Berrettini WH, Bertram H, Burdick KE, Calabrese JR, Calkin CV, Conroy C, Coryell WH, DeModena A, Eyler LT, Feeder S, Fisher C, Frazier N, Frye MA, Gao K, Garnham J, Gershon ES, Goes FS, Goto T, Harrington GJ, Jakobsen P, Kamali M, Kelly M, Leckband SG, Lohoff FW, McCarthy MJ, McInnis MG, Craig D, Millett CE, Mondimore F, Morken G, Nurnberger JI, Donovan CO, ?edegaard KJ, Ryan K, Schinagle M, Shilling PD, Slaney C, Stapp EK, Stautland A, Tarwater B, Zandi PP, Alda M, Fisch KM, Gage FH, Kelsoe JR. PMID: 36991131.
      View in: PubMed   Mentions:    Fields:    
    6. Pharmacotherapy exposure as a marker of disease complexity in bipolar disorder: Associations with clinical & genetic risk factors. Psychiatry Res. 2023 05; 323:115174. Sanchez Ruiz JA, Coombes BJ, Pendegraft RS, Ozerdem A, McElroy SL, Cuellar-Barboza AB, Prieto ML, Frye MA, Winham SJ, Biernacka JM. PMID: 36965208.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Polygenic prediction of bipolar disorder in a Latin American sample. Am J Med Genet B Neuropsychiatr Genet. 2023 Mar 15. Cuellar-Barboza AB, Prieto ML, Coombes BJ, Gardea-Resendez M, Núñez N, Winham SJ, Romo-Nava F, González S, McElroy SL, Frye MA, Biernacka JM. PMID: 36919637.
      View in: PubMed   Mentions:    Fields:    
    8. Association of Polygenic Score and the involvement of Cholinergic and Glutamatergic Pathways with Lithium Treatment Response in Patients with Bipolar Disorder. Res Sq. 2023 Feb 14. Amare A, Thalamuthu A, Schubert KO, Fullerton J, Ahmed M, Hartmann S, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hou L, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka J, Birner A, Marie-Claire C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski P, Dalkner N, Zompo MD, DePaulo JR, Etain B, Jamain S, Falkai P, Forstner AJ, Frisén L, Frye M, Gard S, Garnham J, Goes F, Grigoroiu-Serbanescu M, Fallgatter A, Stegmaier S, Ethofer T, Biere S, Petrova K, Schuster C, Adorjan K, Budde M, Heilbronner M, Kalman J, Kohshour MO, Reich-Erkelenz D, Schaupp S, Schulte E, Senner F, Vogl T, Anghelescu IG, Arolt V, Dannlowski U, Dietrich DE, Figge C, Jäger M, Lang F, Juckel G, Spitzer C, Reimer J, Schmauß M, Schmitt A, Konrad C, von Hagen M, Wiltfang J, Zimmermann J, Andlauer T, Fischer A, Bermpohl F, Kraft V, Matura S, Gryaznova A, Falkenberg I, Yildiz C, Kircher T, Schmidt J, Koch M, Gade K, Trost S, Haußleiter I, Lambert M, Rohenkohl AC, Kraft V, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Ferensztajn-Rochowiak E, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy M, McElroy SL, Colom F, Mitjans M, Mondimore F, Monteleone P, Nievergelt C, Nöthen M, Novak T, O'Donovan C, Ozaki N, Pfennig A, Pisanu C, Potash J, Reif A, Reininghaus E, Rouleau G, Rybakowski JK, Schalling M, Schofield P, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney C, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Veeh J, Witt S, Wright A, Zandi P, Mitchell P, Bauer M, Alda M, Rietschel M, McMahon F, Schulze TG, Millischer V, Clark S, Baune B. PMID: 36824922; PMCID: PMC9949170.
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    9. Comparative Effectiveness of Intravenous Ketamine and Intranasal Esketamine in Clinical Practice Among Patients With Treatment-Refractory Depression: An Observational Study. J Clin Psychiatry. 2023 02 01; 84(2). Singh B, Kung S, Pazdernik V, Schak KM, Geske J, Schulte PJ, Frye MA, Vande Voort JL. PMID: 36724113.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Ketamine-Associated Change in Anhedonia and mTOR Expression in Treatment-Resistant Depression. Biol Psychiatry. 2023 Jan 25. Singh B, Vande Voort JL, Riva-Posse P, Pazdernik VM, Frye MA, Tye SJ. PMID: 36707268.
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    11. Long-Term Lithium Therapy and Thyroid Disorders in Bipolar Disorder: A Historical Cohort Study. Brain Sci. 2023 Jan 12; 13(1). Joseph B, Nunez NA, Pazdernik V, Kumar R, Pahwa M, Ercis M, Ozerdem A, Cuellar-Barboza AB, Romo-Nava F, McElroy SL, Coombes BJ, Biernacka JM, Stan MN, Frye MA, Singh B. PMID: 36672114.
      View in: PubMed   Mentions:
    12. Real-World Clinical Practice Among Patients With Bipolar Disorder and Chronic Kidney Disease on Long-term Lithium Therapy. J Clin Psychopharmacol. 2023 Jan-Feb 01; 43(1):6-11. Kumar R, Joseph B, Pazdernik VM, Geske J, Nuñez NA, Pahwa M, Kashani KB, Veldic M, Betcher HK, Moore KM, Croarkin PE, Ozerdem A, Cuellar-Barboza AB, McElroy SL, Biernacka JM, Frye MA, Singh B. PMID: 36584244.
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    13. Cardiometabolic and endocrine comorbidities in women with bipolar disorder: A systematic review. J Affect Disord. 2023 02 15; 323:841-859. Pahwa M, Kucuker MU, Ho MC, Puspitasari A, Moore KM, Betcher HK, Frye MA, Singh B, Ozerdem A, Veldic M. PMID: 36538952.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Antidepressants that increase mitochondrial energetics may elevate risk of treatment-emergent mania. Mol Psychiatry. 2023 03; 28(3):1020-1026. Gardea-Resendez M, Coombes BJ, Veldic M, Tye SJ, Romo-Nava F, Ozerdem A, Prieto ML, Cuellar-Barboza A, Nunez NA, Singh B, Pendegraft RS, Miola A, McElroy SL, Biernacka JM, Morava E, Kozicz T, Frye MA. PMID: 36513812; PMCID: PMC10005962.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    15. Patients' recovery and non-recovery narratives after intravenous ketamine for treatment-resistant depression. J Affect Disord. 2023 02 15; 323:534-539. Lapidos A, Lopez-Vives D, Sera CE, Ahearn E, Vest E, Senic I, Vande Voort JL, Frye M, Goes FS, Achtyes E, Greden J, Parikh SV. PMID: 36481228.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    16. Examining age of onset phenotype in the spectrum of mood disorders. Int Clin Psychopharmacol. 2023 01 01; 38(1):66-67. Núñez NA, Miola A, Frye MA. PMID: 36373788.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management. World Psychiatry. 2022 Oct; 21(3):364-387. McIntyre RS, Alda M, Baldessarini RJ, Bauer M, Berk M, Correll CU, Fagiolini A, Fountoulakis K, Frye MA, Grunze H, Kessing LV, Miklowitz DJ, Parker G, Post RM, Swann AC, Suppes T, Vieta E, Young A, Maj M. PMID: 36073706; PMCID: PMC9453915.
      View in: PubMed   Mentions: 7  
    18. The Modernization of Clozapine: A Recapitulation of the Past in the United States and the View Forward. J Clin Psychopharmacol. 2022 Nov-Dec 01; 42(6):565-580. Leung JG, de Leon J, Frye MA, Singh B, Cotes RO, McElroy SL. PMID: 36170148.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    19. Plasma TNFSF10 levels associated with acamprosate treatment response in patients with alcohol use disorder. Front Pharmacol. 2022; 13:986238. Ho MF, Zhang C, Moon I, Coombes BJ, Biernacka J, Skime M, Choi DS, Croarkin PE, Frye MA, Ngo Q, Skillon C, Oesterle TS, Karpyak VM, Li H, Weinshilboum RM. PMID: 36120372; PMCID: PMC9475292.
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    20. Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach - CORRIGENDUM. Br J Psychiatry. 2022 08; 221(2):494. Cearns M, Amare AT, Schubert KO, Thalamuthu A, Frank J, Streit F, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry J, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen H, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Degenhardt F, Zompo MD, DePaulo JR, Étain B, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Heilbronner U, Herms S, Hoffmann P, Hofmann A, Hou L, Hsu YH, Jamain S, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Maj M, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O'Donovan C, Ozaki N, Millischer V, Papiol S, Pfennig A, Pisanu C, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, TekolaAyele F, Tortorella A, Turecki G, Veeh J, Vieta E, Witt SH, Roberts G, Zandi PP, Alda M, Bauer M, McMahon FJ, Mitchell PB, Schulze TG, Rietschel M, Clark SR, Baune BT. PMID: 35505515.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients. Transl Psychiatry. 2022 Jul 11; 12(1):278. Schubert KO, Thalamuthu A, Amare AT, Frank J, Streit F, Adl M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Marie-Claire C, Cearns M, Cervantes P, Chen HC, Chillotti C, Cichon S, Clark SR, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Degenhardt F, Del Zompo M, DePaulo JR, Étain B, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Heilbronner U, Herms S, Hoffmann P, Hou L, Hsu YH, Jamain S, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Ferensztajn-Rochowiak E, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Maj M, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O'Donovan C, Ozaki N, Ösby U, Papiol S, Pfennig A, Pisanu C, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shekhtman T, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Tekola-Ayele F, Tortorella A, Turecki G, Veeh J, Vieta E, Witt SH, Roberts G, Zandi PP, Alda M, Bauer M, McMahon FJ, Mitchell PB, Schulze TG, Rietschel M, Baune BT. PMID: 35817769; PMCID: PMC9273602.
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    22. The genetics of bipolar disorder with obesity and type 2 diabetes. J Affect Disord. 2022 09 15; 313:222-231. Miola A, De Filippis E, Veldic M, Ho AM, Winham SJ, Mendoza M, Romo-Nava F, Nunez NA, Gardea Resendez M, Prieto ML, McElroy SL, Biernacka JM, Frye MA, Cuellar-Barboza AB. PMID: 35780966; PMCID: PMC9703971.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Blood-based biomarkers of antidepressant response to ketamine and esketamine: A systematic review and meta-analysis. Mol Psychiatry. 2022 09; 27(9):3658-3669. Medeiros GC, Gould TD, Prueitt WL, Nanavati J, Grunebaum MF, Farber NB, Singh B, Selvaraj S, Machado-Vieira R, Achtyes ED, Parikh SV, Frye MA, Zarate CA, Goes FS. PMID: 35760879; PMCID: PMC9933928.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Association between polarity of first episode and solar insolation in bipolar I disorder. J Psychosom Res. 2022 09; 160:110982. Bauer M, Glenn T, Achtyes ED, Alda M, Agaoglu E, Altinbas K, Andreassen OA, Angelopoulos E, Ardau R, Aydin M, Ayhan Y, Baethge C, Bauer R, Baune BT, Balaban C, Becerra-Palars C, Behere AP, Behere PB, Belete H, Belete T, Belizario GO, Bellivier F, Belmaker RH, Benedetti F, Berk M, Bersudsky Y, Bicakci S, Birabwa-Oketcho H, Bjella TD, Brady C, Cabrera J, Cappucciati M, Castro AMP, Chen WL, Cheung EYW, Chiesa S, Crowe M, Cuomo A, Dallaspezia S, Del Zompo M, Desai P, Dodd S, Etain B, Fagiolini A, Fellendorf FT, Ferensztajn-Rochowiak E, Fiedorowicz JG, Fountoulakis KN, Frye MA, Geoffroy PA, Gonzalez-Pinto A, Gottlieb JF, Grof P, Haarman BCM, Harima H, Hasse-Sousa M, Henry C, Høffding L, Houenou J, Imbesi M, Isometsä ET, Ivkovic M, Janno S, Johnsen S, Kapczinski F, Karakatsoulis GN, Kardell M, Kessing LV, Kim SJ, König B, Kot TL, Koval M, Kunz M, Lafer B, Landén M, Larsen ER, Lenger M, Lewitzka U, Licht RW, Lopez-Jaramillo C, MacKenzie A, Madsen HØ, Madsen SAKA, Mahadevan J, Mahardika A, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Martiny K, Mashima Y, McLoughlin DM, Meesters Y, Melle I, Meza-Urzúa F, Mok YM, Monteith S, Moorthy M, Morken G, Mosca E, Mozzhegorov AA, Munoz R, Mythri SV, Nacef F, Nadella RK, Nakanotani T, Nielsen RE, O'Donovan C, Omrani A, Osher Y, Ouali U, Pantovic-Stefanovic M, Pariwatcharakul P, Petite J, Pfennig A, Ruiz YP, Pinna M, Pompili M, Porter R, Quiroz D, Rabelo-da-Ponte FD, Ramesar R, Rasgon N, Ratta-Apha W, Ratzenhofer M, Redahan M, Reddy MS, Reif A, Reininghaus EZ, Richards JG, Ritter P, Rybakowski JK, Sathyaputri L, Scippa ÂM, Simhandl C, Smith D, Smith J, Stackhouse PW, Stein DJ, Stilwell K, Strejilevich S, Su KP, Subramaniam M, Sulaiman AH, Suominen K, Tanra AJ, Tatebayashi Y, Teh WL, Tondo L, Torrent C, Tuinstra D, Uchida T, Vaaler AE, Vieta E, Viswanath B, Yoldi-Negrete M, Yalcinkaya OK, Young AH, Zgueb Y, Whybrow PC. PMID: 35932492.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism. Mol Metab. 2022 09; 63:101534. Ho MF, Zhang C, Moon I, Wei L, Coombes B, Biernacka J, Skime M, Choi DS, Frye M, Schmidt K, Gliske K, Braughton J, Ngo Q, Skillon C, Seppala M, Oesterle T, Karpyak V, Li H, Weinshilboum R. PMID: 35752286; PMCID: PMC9270258.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    26. Short Term Second-Generation Antidepressant Monotherapy in Acute Depressive Episodes of Bipolar II Disorder: A Systematic Review and Meta-Analysis. Psychopharmacol Bull. 2022 05 31; 52(2):45-72. Park JH, Nuñez NA, Gardea-Resendez M, Gerberi DJ, Breitinger S, Veldic M, Frye MA, Singh B. PMID: 35721812; PMCID: PMC9172552.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Metabolomic signatures of intravenous racemic ketamine associated remission in treatment-resistant depression: A pilot hypothesis generating study. Psychiatry Res. 2022 08; 314:114655. Singh B, MahmoudianDehkordi S, Voort JLV, Han X, Port JD, Frye MA, Kaddurah-Daouk R, Mood Disorders Precision Medicine Consortium (MDPMC). PMID: 35738038.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Quantification of diet quality utilizing the rapid eating assessment for participants-shortened version in bipolar disorder: Implications for prospective depression and cardiometabolic studies. J Affect Disord. 2022 08 01; 310:150-155. Gardea-Resendez M, Winham SJ, Romo-Nava F, Cuellar-Barboza A, Clark MM, Andreazza AC, Cabello-Arreola A, Veldic M, Bond DJ, Singh B, Prieto ML, Nunez NA, Betcher H, Moore KM, Blom T, Colby C, Pendegraft RS, Kelpin SS, Ozerdem A, Miola A, De Filippis E, Biernacka JM, McElroy SL, Frye MA. PMID: 35545158; PMCID: PMC9721194.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative. Bipolar Disord. 2022 11; 24(7):709-719. Burdick KE, Millett CE, Yocum AK, Altimus CM, Andreassen OA, Aubin V, Belzeaux R, Berk M, Biernacka JM, Blumberg HP, Cleare AJ, Diaz-Byrd C, Dubertret C, Etain B, Eyler LT, Forester BP, Fullerton JM, Frye MA, Gard S, Godin O, Haffen E, Klaus F, Lagerberg TV, Leboyer M, Martinez-Aran A, McElroy S, Mitchell PB, Olie E, Olorunfemi P, Passerieux C, Peters AT, Pham DL, Polosan M, Potter JR, Sajatovic M, Samalin L, Schwan R, Shanahan M, Solé B, Strawbridge R, Stuart AL, Torres I, Ueland T, Vieta E, Williams LJ, Wrobel AL, Yatham LN, Young AH, Nierenberg AA, McInnis MG. PMID: 35322518; PMCID: PMC9500115.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder. Front Psychiatry. 2022; 13:884217. Nunez NA, Coombes BJ, Romo-Nava F, Bond DJ, Vande Voort J, Croarkin PE, Leibman N, Gardea Resendez M, Veldic M, Betcher H, Singh B, Colby C, Cuellar-Barboza A, Prieto M, Moore KM, Ozerdem A, McElroy SL, Frye MA, Biernacka JM. PMID: 35492709; PMCID: PMC9047940.
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    31. Implementation of preemptive DNA sequence-based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study. Genet Med. 2022 05; 24(5):1062-1072. Wang L, Scherer SE, Bielinski SJ, Muzny DM, Jones LA, Black JL, Moyer AM, Giri J, Sharp RR, Matey ET, Wright JA, Oyen LJ, Nicholson WT, Wiepert M, Sullard T, Curry TB, Rohrer Vitek CR, McAllister TM, St Sauver JL, Caraballo PJ, Lazaridis KN, Venner E, Qin X, Hu J, Kovar CL, Korchina V, Walker K, Doddapaneni H, Wu TJ, Raj R, Denson S, Liu W, Chandanavelli G, Zhang L, Wang Q, Kalra D, Karow MB, Harris KJ, Sicotte H, Peterson SE, Barthel AE, Moore BE, Skierka JM, Kluge ML, Kotzer KE, Kloke K, Vander Pol JM, Marker H, Sutton JA, Kekic A, Ebenhoh A, Bierle DM, Schuh MJ, Grilli C, Erickson S, Umbreit A, Ward L, Crosby S, Nelson EA, Levey S, Elliott M, Peters SG, Pereira N, Frye M, Shamoun F, Goetz MP, Kullo IJ, Wermers R, Anderson JA, Formea CM, El Melik RM, Zeuli JD, Herges JR, Krieger CA, Hoel RW, Taraba JL, St Thomas SR, Absah I, Bernard ME, Fink SR, Gossard A, Grubbs PL, Jacobson TM, Takahashi P, Zehe SC, Buckles S, Bumgardner M, Gallagher C, Fee-Schroeder K, Nicholas NR, Powers ML, Ragab AK, Richardson DM, Stai A, Wilson J, Pacyna JE, Olson JE, Sutton EJ, Beck AT, Horrow C, Kalari KR, Larson NB, Liu H, Wang L, Lopes GS, Borah BJ, Freimuth RR, Zhu Y, Jacobson DJ, Hathcock MA, Armasu SM, McGree ME, Jiang R, Koep TH, Ross JL, Hilden MG, Bosse K, Ramey B, Searcy I, Boerwinkle E, Gibbs RA, Weinshilboum RM. PMID: 35331649; PMCID: PMC9272414.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
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    95. Fly eyes are not still: a motion illusion in Drosophila flight supports parallel visual processing. J Exp Biol. 2020 05 28; 223(Pt 10). Salem W, Cellini B, Frye MA, Mongeau JM. PMID: 32321749; PMCID: PMC7272343.
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    96. Inferring multimodal latent topics from electronic health records. Nat Commun. 2020 05 21; 11(1):2536. Li Y, Nair P, Lu XH, Wen Z, Wang Y, Dehaghi AAK, Miao Y, Liu W, Ordog T, Biernacka JM, Ryu E, Olson JE, Frye MA, Liu A, Guo L, Marelli A, Ahuja Y, Davila-Velderrain J, Kellis M. PMID: 32439869; PMCID: PMC7242436.
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    97. Non-canonical Receptive Field Properties and Neuromodulation of Feature-Detecting Neurons in Flies. Curr Biol. 2020 07 06; 30(13):2508-2519.e6. Städele C, Keles MF, Mongeau JM, Frye MA. PMID: 32442460; PMCID: PMC7343589.
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    98. Feasibility Study of Stress Management and Resiliency Training (SMART) in Patients With Major Depressive Disorder. Prim Care Companion CNS Disord. 2020 Apr 30; 22(3). Seshadri A, Clark MM, Kung S, Fuller-Tyszkiewicz M, Sood A, Dammen KC, Rico JA, Tye SJ, McGillivray J, Frye MA. PMID: 32369689.
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    103. Differential Dorsolateral Prefrontal Cortex Proteomic Profiles of Suicide Victims with Mood Disorders. Genes (Basel). 2020 02 27; 11(3). Cabello-Arreola A, Ho AM, Ozerdem A, Cuellar-Barboza AB, Kucuker MU, Heppelmann CJ, Charlesworth MC, Ceylan D, Stockmeier CA, Rajkowska G, Frye MA, Choi DS, Veldic M. PMID: 32120974; PMCID: PMC7140872.
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    104. Inhibitory Interactions and Columnar Inputs to an Object Motion Detector in Drosophila. Cell Rep. 2020 02 18; 30(7):2115-2124.e5. Keles MF, Hardcastle BJ, Städele C, Xiao Q, Frye MA. PMID: 32075756; PMCID: PMC7210872.
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    108. Methylation of Brain Derived Neurotrophic Factor (BDNF) Val66Met CpG site is associated with early onset bipolar disorder. J Affect Disord. 2020 04 15; 267:96-102. Nassan M, Veldic M, Winham S, Frye MA, Larrabee B, Colby C, Biernacka J, Bellia F, Pucci M, Terenius L, Vukojevic V, D'Addario C. PMID: 32063579.
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    110. Efficacy and tolerability of adjunctive modafinil/armodafinil in bipolar depression: A meta-analysis of randomized controlled trials. Bipolar Disord. 2020 03; 22(2):109-120. Nunez NA, Singh B, Romo-Nava F, Joseph B, Veldic M, Cuellar-Barboza A, Cabello Arreola A, Vande Voort JL, Croarkin P, Moore KM, Biernacka J, McElroy SL, Frye MA. PMID: 31643130.
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    111. Predictors of psychosocial outcome of bipolar disorder: data from the Stanley Foundation Bipolar Network. Int J Bipolar Disord. 2019 Dec 16; 7(1):28. Bennett F, Hodgetts S, Close A, Frye M, Grunze H, Keck P, Kupka R, McElroy S, Nolen W, Post R, Schärer L, Suppes T, Sharma AN. PMID: 31840207; PMCID: PMC6911815.
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    113. Statistical methods for testing X chromosome variant associations: application to sex-specific characteristics of bipolar disorder. Biol Sex Differ. 2019 12 09; 10(1):57. Jons WA, Colby CL, McElroy SL, Frye MA, Biernacka JM, Winham SJ. PMID: 31818333; PMCID: PMC6902568.
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    114. Neuromodulation of insect motion vision. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2020 03; 206(2):125-137. Cheng KY, Frye MA. PMID: 31811398.
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    115. Association of Cytomegalovirus and Toxoplasma gondii Antibody Titers With Bipolar Disorder. JAMA Psychiatry. 2019 12 01; 76(12):1285-1293. Frye MA, Coombes BJ, McElroy SL, Jones-Brando L, Bond DJ, Veldic M, Romo-Nava F, Bobo WV, Singh B, Colby C, Skime MK, Biernacka JM, Yolken R. PMID: 31532468; PMCID: PMC6751798.
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    117. The Association Between Body Mass Index and Remission Rates in Patients With Treatment-Resistant Depression Who Received Intravenous Ketamine. J Clin Psychiatry. 2019 11 12; 80(6). Singh B, Bobo WV, Rasmussen KG, Stoppel CJ, Rico JA, Schak KM, Biernacka JM, Frye MA, Vande Voort JL. PMID: 31721482.
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    119. Adding Increased Energy or Activity to Criterion (A) of the DSM-5 Definition of Hypomania and Mania: Effect on the Diagnoses of 907 Patients From the Bipolar Collaborative Network. J Clin Psychiatry. 2019 10 29; 80(6). Fredskild MU, Mintz J, Frye MA, McElroy SL, Nolen WA, Kupka R, Grunze H, Keck PE, Post RM, Kessing LV, Suppes T. PMID: 31665571.
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    120. Drosophila Neuroscience: Should I Land or Should I Jump? Curr Biol. 2019 10 21; 29(20):R1089-R1091. Städele C, Rimniceanu M, Frye MA. PMID: 31639356.
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    130. Olfactory and Neuromodulatory Signals Reverse Visual Object Avoidance to Approach in Drosophila. Curr Biol. 2019 06 17; 29(12):2058-2065.e2. Cheng KY, Colbath RA, Frye MA. PMID: 31155354; PMCID: PMC6615044.
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    144. Sex-specific association of depressive disorder and transient emotional states with alcohol consumption in male and female alcoholics. Drug Alcohol Depend. 2019 03 01; 196:31-39. Karpyak VM, Geske JR, Hall-Flavin DK, Loukianova LL, Schneekloth TD, Skime MK, Seppala M, Dawson G, Frye MA, Choi DS, Biernacka JM. PMID: 30660937.
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    163. Bioenergetics and synaptic plasticity as potential targets for individualizing treatment for depression. Neurosci Biobehav Rev. 2018 07; 90:212-220. Price JB, Bronars C, Erhardt S, Cullen KR, Schwieler L, Berk M, Walder K, McGee SL, Frye MA, Tye SJ. PMID: 29656032.
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    164. Racial disparities in bipolar disorder treatment and research: a call to action. Bipolar Disord. 2018 09; 20(6):506-514. Akinhanmi MO, Biernacka JM, Strakowski SM, McElroy SL, Balls Berry JE, Merikangas KR, Assari S, McInnis MG, Schulze TG, LeBoyer M, Tamminga C, Patten C, Frye MA. PMID: 29527766; PMCID: PMC6175457.
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    166. Benefits of and Barriers to Pharmacogenomics-Guided Treatment for Major Depressive Disorder. Clin Pharmacol Ther. 2018 05; 103(5):767-769. Ahmed AT, Weinshilboum R, Frye MA. PMID: 29388201; PMCID: PMC6380658.
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    167. Prevalence of axis II comorbidities in bipolar disorder: relationship to mood state. Bipolar Disord. 2018 06; 20(4):303-312. Post RM, Leverich GS, McElroy S, Kupka R, Suppes T, Altshuler L, Nolen W, Frye M, Keck P, Grunze H, Hellemann G. PMID: 29369448.
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    168. Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics. Transl Psychiatry. 2018 01 10; 8(1):10. Liu D, Ray B, Neavin DR, Zhang J, Athreya AP, Biernacka JM, Bobo WV, Hall-Flavin DK, Skime MK, Zhu H, Jenkins GD, Batzler A, Kalari KR, Boakye-Agyeman F, Matson WR, Bhasin SS, Mushiroda T, Nakamura Y, Kubo M, Iyer RK, Wang L, Frye MA, Kaddurah-Daouk R, Weinshilboum RM. PMID: 29317604; PMCID: PMC5802574.
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    169. Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study. JAMA Psychiatry. 2018 01 01; 75(1):65-74. International Consortium on Lithium Genetics (ConLi+Gen), Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, Heilbronner U, Degenhardt F, Tekola-Ayele F, Hsu YH, Shekhtman T, Adli M, Akula N, Akiyama K, Ardau R, Arias B, Aubry JM, Backlund L, Bhattacharjee AK, Bellivier F, Benabarre A, Bengesser S, Biernacka JM, Birner A, Brichant-Petitjean C, Cervantes P, Chen HC, Chillotti C, Cichon S, Cruceanu C, Czerski PM, Dalkner N, Dayer A, Del Zompo M, DePaulo JR, Étain B, Falkai P, Forstner AJ, Frisen L, Frye MA, Fullerton JM, Gard S, Garnham JS, Goes FS, Grigoroiu-Serbanescu M, Grof P, Hashimoto R, Hauser J, Herms S, Hoffmann P, Hofmann A, Jamain S, Jiménez E, Kahn JP, Kassem L, Kuo PH, Kato T, Kelsoe J, Kittel-Schneider S, Kliwicki S, König B, Kusumi I, Laje G, Landén M, Lavebratt C, Leboyer M, Leckband SG, Tortorella A, Manchia M, Martinsson L, McCarthy MJ, McElroy S, Colom F, Mitjans M, Mondimore FM, Monteleone P, Nievergelt CM, Nöthen MM, Novák T, O'Donovan C, Ozaki N, Ösby U, Pfennig A, Potash JB, Reif A, Reininghaus E, Rouleau GA, Rybakowski JK, Schalling M, Schofield PR, Schweizer BW, Severino G, Shilling PD, Shimoda K, Simhandl C, Slaney CM, Squassina A, Stamm T, Stopkova P, Maj M, Turecki G, Vieta E, Volkert J, Witt S, Wright A, Zandi PP, Mitchell PB, Bauer M, Alda M, Rietschel M, McMahon FJ, Schulze TG, Baune BT. PMID: 29121268; PMCID: PMC5833535.
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    170. Genetic Risk Score Analysis in Early-Onset Bipolar Disorder. J Clin Psychiatry. 2017 Nov-Dec; 78(9):1337-1343. Croarkin PE, Luby JL, Cercy K, Geske JR, Veldic M, Simonson M, Joshi PT, Wagner KD, Walkup JT, Nassan MM, Cuellar-Barboza AB, Casuto L, McElroy SL, Jensen PS, Frye MA, Biernacka JM. PMID: 28199072; PMCID: PMC5818996.
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    171. A Genome-Wide Search for Bipolar Disorder Risk Loci Modified by Mitochondrial Genome Variation. Mol Neuropsychiatry. 2018 Feb; 3(3):125-134. Ryu E, Nassan M, Jenkins GD, Armasu SM, Andreazza A, McElroy SL, Vawter MP, Frye MA, Biernacka JM. PMID: 29594131; PMCID: PMC5836158.
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    174. Drosophila Spatiotemporally Integrates Visual Signals to Control Saccades. Curr Biol. 2017 Oct 09; 27(19):2901-2914.e2. Mongeau JM, Frye MA. PMID: 28943085; PMCID: PMC5634948.
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    175. The relative influence of individual risk factors for attempted suicide in patients with bipolar I versus bipolar II disorder. J Affect Disord. 2018 01 01; 225:489-494. Bobo WV, Na PJ, Geske JR, McElroy SL, Frye MA, Biernacka JM. PMID: 28865370.
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    176. Association of the serotonin transporter-linked polymorphic region genotype with lower bone mineral density. Transl Psychiatry. 2017 08 22; 7(8):e1213. Lapid MI, Kung S, Frye MA, Biernacka JM, Geske JR, Drake MT, Jankowski MD, Clarke BL. PMID: 28892067; PMCID: PMC5611748.
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    177. Metabotropic glutamate receptors as emerging research targets in bipolar disorder. Psychiatry Res. 2017 11; 257:327-337. Blacker CJ, Lewis CP, Frye MA, Veldic M. PMID: 28800512.
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    178. Differential SLC1A2 Promoter Methylation in Bipolar Disorder With or Without Addiction. Front Cell Neurosci. 2017; 11:217. Jia YF, Choi Y, Ayers-Ringler JR, Biernacka JM, Geske JR, Lindberg DR, McElroy SL, Frye MA, Choi DS, Veldic M. PMID: 28785205; PMCID: PMC5520464.
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    179. Solar insolation in springtime influences age of onset of bipolar I disorder. Acta Psychiatr Scand. 2017 Dec; 136(6):571-582. Bauer M, Glenn T, Alda M, Aleksandrovich MA, Andreassen OA, Angelopoulos E, Ardau R, Ayhan Y, Baethge C, Bharathram SR, Bauer R, Baune BT, Becerra-Palars C, Bellivier F, Belmaker RH, Berk M, Bersudsky Y, Bicakci S, Birabwa-Oketcho H, Bjella TD, Bossini L, Cabrera J, Cheung EYW, Del Zompo M, Dodd S, Donix M, Etain B, Fagiolini A, Fountoulakis KN, Frye MA, Gonzalez-Pinto A, Gottlieb JF, Grof P, Harima H, Henry C, Isometsä ET, Janno S, Kapczinski F, Kardell M, Khaldi S, Kliwicki S, König B, Kot TL, Krogh R, Kunz M, Lafer B, Landén M, Larsen ER, Lewitzka U, Licht RW, Lopez-Jaramillo C, MacQueen G, Manchia M, Marsh W, Martinez-Cengotitabengoa M, Melle I, Meza-Urzúa F, Yee Ming M, Monteith S, Morken G, Mosca E, Munoz R, Mythri SV, Nacef F, Nadella RK, Nery FG, Nielsen RE, O'Donovan C, Omrani A, Osher Y, Østermark Sørensen H, Ouali U, Pica Ruiz Y, Pilhatsch M, Pinna M, da Ponte FDR, Quiroz D, Ramesar R, Rasgon N, Reddy MS, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Scippa ÂM, Severus E, Simhandl C, Stein DJ, Strejilevich S, Subramaniam M, Sulaiman AH, Suominen K, Tagata H, Tatebayashi Y, Tondo L, Torrent C, Vaaler AE, Veeh J, Vieta E, Viswanath B, Yoldi-Negrete M, Zetin M, Zgueb Y, Whybrow PC. PMID: 28722128.
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    180. Validation of a Teaching Effectiveness Assessment in Psychiatry Continuing Medical Education. Acad Psychiatry. 2018 Aug; 42(4):458-463. Palmer BA, Frye MA, Vickers Douglas KS, Staab JP, Bright RP, Schleck CD, Mandrekar JN, Mahapatra S, Beckman TJ, Wittich CM. PMID: 28685348.
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    181. Exploring hepsin functional genetic variation association with disease specific protein expression in bipolar disorder: Applications of a proteomic informed genomic approach. J Psychiatr Res. 2017 12; 95:208-212. Nassan M, Jia YF, Jenkins G, Colby C, Feeder S, Choi DS, Veldic M, McElroy SL, Bond DJ, Weinshilboum R, Biernacka JM, Frye MA. PMID: 28886448.
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    182. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Transl Psychiatry. 2017 06 20; 7(6):e1155. Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, Adolfsson R, Air TM, Akil H, Alda M, Alliey-Rodriguez N, Andreassen OA, Babadjanova G, Bass NJ, Bauer M, Baune BT, Bellivier F, Bergen S, Bethell A, Biernacka JM, Blackwood DHR, Boks MP, Boomsma DI, Børglum AD, Borrmann-Hassenbach M, Brennan P, Budde M, Buttenschøn HN, Byrne EM, Cervantes P, Clarke TK, Craddock N, Cruceanu C, Curtis D, Czerski PM, Dannlowski U, Davis T, de Geus EJC, Di Florio A, Djurovic S, Domenici E, Edenberg HJ, Etain B, Fischer SB, Forty L, Fraser C, Frye MA, Fullerton JM, Gade K, Gershon ES, Giegling I, Gordon SD, Gordon-Smith K, Grabe HJ, Green EK, Greenwood TA, Grigoroiu-Serbanescu M, Guzman-Parra J, Hall LS, Hamshere M, Hauser J, Hautzinger M, Heilbronner U, Herms S, Hitturlingappa S, Hoffmann P, Holmans P, Hottenga JJ, Jamain S, Jones I, Jones LA, Juréus A, Kahn RS, Kammerer-Ciernioch J, Kirov G, Kittel-Schneider S, Kloiber S, Knott SV, Kogevinas M, Landén M, Leber M, Leboyer M, Li QS, Lissowska J, Lucae S, Martin NG, Mayoral-Cleries F, McElroy SL, McIntosh AM, McKay JD, McQuillin A, Medland SE, Middeldorp CM, Milaneschi Y, Mitchell PB, Montgomery GW, Morken G, Mors O, Mühleisen TW, Müller-Myhsok B, Myers RM, Nievergelt CM, Nurnberger JI, O'Donovan MC, Loohuis LMO, Ophoff R, Oruc L, Owen MJ, Paciga SA, Penninx BWJH, Perry A, Pfennig A, Potash JB, Preisig M, Reif A, Rivas F, Rouleau GA, Schofield PR, Schulze TG, Schwarz M, Scott L, Sinnamon GCB, Stahl EA, Strauss J, Turecki G, Van der Auwera S, Vedder H, Vincent JB, Willemsen G, Witt CC, Wray NR, Xi HS, Bipolar Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Tadic A, Dahmen N, Schott BH, Cichon S, Nöthen MM, Ripke S, Mobascher A, Rujescu D, Lieb K, Roepke S, Schmahl C, Bohus M, Rietschel M. PMID: 28632202; PMCID: PMC5537640.
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    183. A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders. JAMA Psychiatry. 2017 Apr 01; 74(4):399-405. Sanacora G, Frye MA, McDonald W, Mathew SJ, Turner MS, Schatzberg AF, Summergrad P, Nemeroff CB, American Psychiatric Association (APA) Council of Research Task Force on Novel Biomarkers and Treatm. PMID: 28249076.
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    184. Visual Input to the Drosophila Central Complex by Developmentally and Functionally Distinct Neuronal Populations. Curr Biol. 2017 Apr 24; 27(8):1098-1110. Omoto JJ, Keles MF, Nguyen BM, Bolanos C, Lovick JK, Frye MA, Hartenstein V. PMID: 28366740; PMCID: PMC5446208.
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    185. Object-Detecting Neurons in Drosophila. Curr Biol. 2017 Mar 06; 27(5):680-687. Keles MF, Frye MA. PMID: 28190726; PMCID: PMC5340600.
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    186. The eyes have it. Elife. 2017 02 06; 6. Keles M, Frye MA. PMID: 28165325; PMCID: PMC5293486.
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    187. More childhood onset bipolar disorder in the United States than Canada or Europe: Implications for treatment and prevention. Neurosci Biobehav Rev. 2017 Mar; 74(Pt A):204-213. Post RM, Altshuler LL, Kupka R, McElroy SL, Frye MA, Rowe M, Grunze H, Suppes T, Keck PE, Leverich GS, Nolen WA. PMID: 28119069.
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    190. An Exploratory Study of Spectroscopic Glutamatergic Correlates of Cortical Excitability in Depressed Adolescents. Front Neural Circuits. 2016; 10:98. Lewis CP, Port JD, Frye MA, Vande Voort JL, Ameis SH, Husain MM, Daskalakis ZJ, Croarkin PE. PMID: 27965544; PMCID: PMC5127083.
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    194. Mitochondrial DNA sequence data reveals association of haplogroup U with psychosis in bipolar disorder. J Psychiatr Res. 2017 01; 84:221-226. Frye MA, Ryu E, Nassan M, Jenkins GD, Andreazza AC, Evans JM, McElroy SL, Oglesbee D, Highsmith WE, Biernacka JM. PMID: 27770741.
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    200. Elevated Glutamate Levels in the Left Dorsolateral Prefrontal Cortex Are Associated with Higher Cravings for Alcohol. Alcohol Clin Exp Res. 2016 08; 40(8):1609-16. Frye MA, Hinton DJ, Karpyak VM, Biernacka JM, Gunderson LJ, Geske J, Feeder SE, Choi DS, Port JD. PMID: 27439218.
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    201. Depressive symptom severity and mortality in older adults undergoing percutaneous coronary intervention. Int J Cardiol. 2016 Oct 15; 221:521-3. Gharacholou SM, Roger VL, Lennon RJ, Frye MA, Rihal CS, Singh M. PMID: 27414733; PMCID: PMC5106288.
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    202. Pharmacokinetic Pharmacogenetic Prescribing Guidelines for Antidepressants: A Template for Psychiatric Precision Medicine. Mayo Clin Proc. 2016 07; 91(7):897-907. Nassan M, Nicholson WT, Elliott MA, Rohrer Vitek CR, Black JL, Frye MA. PMID: 27289413.
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    205. Ketamine: stimulating antidepressant treatment? BJPsych Open. 2016 May; 2(3):e5-e9. Malhi GS, Byrow Y, Cassidy F, Cipriani A, Demyttenaere K, Frye MA, Gitlin M, Kennedy SH, Ketter TA, Lam RW, McShane R, Mitchell AJ, Ostacher MJ, Rizvi SJ, Thase ME, Tohen M. PMID: 27703782; PMCID: PMC4995167.
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    207. Gender-specific effects of comorbid depression and anxiety on the propensity to drink in negative emotional states. Addiction. 2016 08; 111(8):1366-75. Karpyak VM, Biernacka JM, Geske JR, Abulseoud OA, Brunner MD, Chauhan M, Hall-Flavin DK, Lewis KA, Loukianova LL, Melnyk GJ, Onsrud DA, Proctor BD, Schneekloth TD, Skime MK, Wittkopp JE, Frye MA, Mrazek DA. PMID: 27009547; PMCID: PMC4940218.
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    209. Stimulation-Induced Transient Nonmotor Psychiatric Symptoms following Subthalamic Deep Brain Stimulation in Patients with Parkinson's Disease: Association with Clinical Outcomes and Neuroanatomical Correlates. Stereotact Funct Neurosurg. 2016; 94(2):93-101. Abulseoud OA, Kasasbeh A, Min HK, Fields JA, Tye SJ, Goerss S, Knight EJ, Sampson SM, Klassen BT, Matsumoto JY, Stoppel C, Lee KH, Frye MA. PMID: 27093641; PMCID: PMC4850907.
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    210. Mixed Depression in Bipolar Disorder: Prevalence Rate and Clinical Correlates During Naturalistic Follow-Up in the Stanley Bipolar Network. Am J Psychiatry. 2016 Oct 01; 173(10):1015-1023. Miller S, Suppes T, Mintz J, Hellemann G, Frye MA, McElroy SL, Nolen WA, Kupka R, Leverich GS, Grunze H, Altshuler LL, Keck PE, Post RM. PMID: 27079133.
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    211. KETAMINE FOR TREATMENT-RESISTANT UNIPOLAR AND BIPOLAR MAJOR DEPRESSION: CRITICAL REVIEW AND IMPLICATIONS FOR CLINICAL PRACTICE. Depress Anxiety. 2016 08; 33(8):698-710. Bobo WV, Vande Voort JL, Croarkin PE, Leung JG, Tye SJ, Frye MA. PMID: 27062450.
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    212. Antidepressant actions of lateral habenula deep brain stimulation differentially correlate with CaMKII/GSK3/AMPK signaling locally and in the infralimbic cortex. Behav Brain Res. 2016 06 01; 306:170-7. Kim Y, Morath B, Hu C, Byrne LK, Sutor SL, Frye MA, Tye SJ. PMID: 26956153.
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    214. Potential Risks of Poorly Monitored Ketamine Use in Depression Treatment. Am J Psychiatry. 2016 Mar 01; 173(3):215-8. Schak KM, Vande Voort JL, Johnson EK, Kung S, Leung JG, Rasmussen KG, Palmer BA, Frye MA. PMID: 26926127.
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    216. Long-term safety and efficacy of armodafinil in bipolar depression: A 6-month open-label extension study. J Affect Disord. 2016 Jun; 197:51-7. Ketter TA, Amchin J, Frye MA, Gross N. PMID: 26970266.
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    217. TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: pharmacometabolomics-informed pharmacogenomics. Mol Psychiatry. 2016 12; 21(12):1717-1725. Gupta M, Neavin D, Liu D, Biernacka J, Hall-Flavin D, Bobo WV, Frye MA, Skime M, Jenkins GD, Batzler A, Kalari K, Matson W, Bhasin SS, Zhu H, Mushiroda T, Nakamura Y, Kubo M, Wang L, Kaddurah-Daouk R, Weinshilboum RM. PMID: 26903268; PMCID: PMC5003027.
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    222. Long-term risk of myocardial infarction and stroke in bipolar I disorder: A population-based Cohort Study. J Affect Disord. 2016 Apr; 194:120-7. Prieto ML, Schenck LA, Kruse JL, Klaas JP, Chamberlain AM, Bobo WV, Bellivier F, Leboyer M, Roger VL, Brown RD, Rocca WA, Frye MA. PMID: 26820761; PMCID: PMC4909505.
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    223. Lipid peroxidation biomarkers in adolescents with or at high-risk for bipolar disorder. J Affect Disord. 2016 Mar 01; 192:176-83. Scola G, McNamara RK, Croarkin PE, Leffler JM, Cullen KR, Geske JR, Biernacka JM, Frye MA, DelBello MP, Andreazza AC. PMID: 26735329; PMCID: PMC5549852.
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    224. Feasibility of investigating differential proteomic expression in depression: implications for biomarker development in mood disorders. Transl Psychiatry. 2015 Dec 08; 5:e689. Frye MA, Nassan M, Jenkins GD, Kung S, Veldic M, Palmer BA, Feeder SE, Tye SJ, Choi DS, Biernacka JM. PMID: 26645624; PMCID: PMC5068585.
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    225. Transcranial magnetic stimulation potentiates glutamatergic neurotransmission in depressed adolescents. Psychiatry Res Neuroimaging. 2016 Jan 30; 247:25-33. Croarkin PE, Nakonezny PA, Wall CA, Murphy LL, Sampson SM, Frye MA, Port JD. PMID: 26651598; PMCID: PMC4716879.
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    227. Prevalence and correlates of DSM-5 eating disorders in patients with bipolar disorder. J Affect Disord. 2016 Feb; 191:216-21. McElroy SL, Crow S, Blom TJ, Biernacka JM, Winham SJ, Geske J, Cuellar-Barboza AB, Bobo WV, Prieto ML, Veldic M, Mori N, Seymour LR, Bond DJ, Frye MA. PMID: 26682490.
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    228. Increases in multiple psychiatric disorders in parents and grandparents of patients with bipolar disorder from the USA compared with The Netherlands and Germany. Psychiatr Genet. 2015 Oct; 25(5):194-200. Post RM, Leverich GS, Kupka R, Keck PE, McElroy SL, Altshuler LL, Frye MA, Rowe M, Grunze H, Suppes T, Nolen WA. PMID: 26146875.
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    229. Telepsychiatry for post-traumatic stress disorder: a call for action in the Syrian conflict. Lancet Psychiatry. 2015 Oct; 2(10):866. Nassan M, Frye MA, Adi A, Alarcón RD. PMID: 26462214.
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    230. Screening for bipolar disorders: Clinical utilization of the Mood Disorders Questionnaire on an inpatient mood disorders unit. J Affect Disord. 2015 Dec 01; 188:97-100. Kung S, Palmer BA, Lapid MI, Poppe KA, Alarcon RD, Frye MA. PMID: 26344754.
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    231. Randomized, placebo-controlled, adjunctive study of armodafinil for bipolar I depression: implications of novel drug design and heterogeneity of concurrent bipolar maintenance treatments. Int J Bipolar Disord. 2015 Dec; 3(1):34. Frye MA, Amchin J, Bauer M, Adler C, Yang R, Ketter TA. PMID: 26330288; PMCID: PMC4556715.
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    233. Sex differences in the risk of rapid cycling and other indicators of adverse illness course in patients with bipolar I and II disorder. Bipolar Disord. 2015 Sep; 17(6):670-6. Erol A, Winham SJ, McElroy SL, Frye MA, Prieto ML, Cuellar-Barboza AB, Fuentes M, Geske J, Mori N, Biernacka JM, Bobo WV. PMID: 26529373.
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    234. National survey and community advisory board development for a bipolar disorder biobank. Bipolar Disord. 2015 Sep; 17(6):598-605. Frye MA, Doederlein A, Koenig B, McElroy SL, Nassan M, Seymour LR, Biernacka JM, Daniels AS. PMID: 26291791; PMCID: PMC4643402.
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    235. Elevated baseline serum glutamate as a pharmacometabolomic biomarker for acamprosate treatment outcome in alcohol-dependent subjects. Transl Psychiatry. 2015 Aug 18; 5:e621. Nam HW, Karpyak VM, Hinton DJ, Geske JR, Ho AM, Prieto ML, Biernacka JM, Frye MA, Weinshilboum RM, Choi DS. PMID: 26285131; PMCID: PMC4564571.
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    237. Peripheral proinflammatory markers associated with ketamine response in a preclinical model of antidepressant-resistance. Behav Brain Res. 2015 Oct 15; 293:198-202. Walker AJ, Foley BM, Sutor SL, McGillivray JA, Frye MA, Tye SJ. PMID: 26209292.
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    238. Development of a bipolar disorder biobank: differential phenotyping for subsequent biomarker analyses. Int J Bipolar Disord. 2015 Dec; 3(1):30. Frye MA, McElroy SL, Fuentes M, Sutor B, Schak KM, Galardy CW, Palmer BA, Prieto ML, Kung S, Sola CL, Ryu E, Veldic M, Geske J, Cuellar-Barboza A, Seymour LR, Mori N, Crowe S, Rummans TA, Biernacka JM. PMID: 26105627; PMCID: PMC4478187.
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    240. Concomitant benzodiazepine use attenuates ketamine response: implications for large scale study design and clinical development. J Clin Psychopharmacol. 2015 Jun; 35(3):334-6. Frye MA, Blier P, Tye SJ. PMID: 25928701.
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    241. Group behavior: social context modulates behavioral responses to sensory stimuli. Curr Biol. 2015 Jun 01; 25(11):R467-9. Wasserman SM, Frye MA. PMID: 26035792.
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    242. Neurons forming optic glomeruli compute figure-ground discriminations in Drosophila. J Neurosci. 2015 May 13; 35(19):7587-99. Aptekar JW, Keles MF, Lu PM, Zolotova NM, Frye MA. PMID: 25972183; PMCID: PMC4429157.
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    246. Sex differences in mania phenotype and ethanol consumption in the lateral hypothalamic kindled rat model. Transl Psychiatry. 2015 Mar 24; 5:e534. Abulseoud OA, Gawad NA, Mohamed K, Vadnie C, Camsari UM, Karpyak V, Frye MA, Choi DS. PMID: 25803497; PMCID: PMC4354358.
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    247. Elementary motion detectors. Curr Biol. 2015 Mar 16; 25(6):R215-R217. Frye M. PMID: 25784034.
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    249. Psychiatric Autoimmunity: N-Methyl-D-Aspartate Receptor IgG and Beyond. Psychosomatics. 2015 May-Jun; 56(3):227-41. Kruse JL, Lapid MI, Lennon VA, Klein CJ, Toole OO, Pittock SJ, Strand EA, Frye MA, McKeon A. PMID: 25975857.
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    259. Method and software for using m-sequences to characterize parallel components of higher-order visual tracking behavior in Drosophila. Front Neural Circuits. 2014; 8:130. Aptekar JW, Keles MF, Mongeau JM, Lu PM, Frye MA, Shoemaker PA. PMID: 25400550; PMCID: PMC4215624.
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    325. Differences in demographic composition and in work, social, and functional limitations among the populations with unipolar depression and bipolar disorder: results from a nationally representative sample. Health Qual Life Outcomes. 2011 Oct 13; 9:90. Shippee ND, Shah ND, Williams MD, Moriarty JP, Frye MA, Ziegenfuss JY. PMID: 21995725; PMCID: PMC3207868.
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    326. International consensus group on depression prevention in bipolar disorder. J Clin Psychiatry. 2011 Oct; 72(10):1295-310. Frye MA, Ha K, Kanba S, Kato T, McElroy SL, Özerdem A, Vázquez G, Vieta E. PMID: 22075097.
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    327. Trazodone and alcohol relapse: a retrospective study following residential treatment. Am J Addict. 2011 Nov-Dec; 20(6):525-9. Kolla BP, Schneekloth TD, Biernacka JM, Frye MA, Mansukhani MP, Hall-Flavin DK, Karpyak VM, Loukianova LL, Lesnick TG, Mrazek D. PMID: 21999497.
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    328. Review of pharmacological treatment in mood disorders and future directions for drug development. Neuropsychopharmacology. 2012 Jan; 37(1):77-101. Li X, Frye MA, Shelton RC. PMID: 21900884; PMCID: PMC3238080.
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    329. Direct costs of bipolar disorder versus other chronic conditions: an employer-based health plan analysis. Psychiatr Serv. 2011 Sep; 62(9):1073-8. Williams MD, Shah ND, Wagie AE, Wood DL, Frye MA. PMID: 21885587.
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    330. Odor identity influences tracking of temporally patterned plumes in Drosophila. BMC Neurosci. 2011 Jun 27; 12:62. Krishnan P, Duistermars BJ, Frye MA. PMID: 21708035; PMCID: PMC3145592.
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    331. Pharmacogenomics of antidepressant induced mania: a review and meta-analysis of the serotonin transporter gene (5HTTLPR) association. J Affect Disord. 2012 Jan; 136(1-2):e21-e29. Biernacka JM, McElroy SL, Crow S, Sharp A, Benitez J, Veldic M, Kung S, Cunningham JM, Post RM, Mrazek D, Frye MA. PMID: 21680025.
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    332. Voltage-dependent mania after subthalamic nucleus deep brain stimulation in Parkinson's disease: a case report. Biol Psychiatry. 2011 Jul 15; 70(2):e5-7. Chopra A, Tye SJ, Lee KH, Matsumoto J, Klassen B, Adams AC, Stead M, Sampson S, Kall BA, Frye MA. PMID: 21414603.
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    333. Differential clinical characteristics, medication usage, and treatment response of bipolar disorder in the US versus The Netherlands and Germany. Int Clin Psychopharmacol. 2011 Mar; 26(2):96-106. Post RM, Leverich GS, Altshuler LL, Frye MA, Suppes T, Keck PE, McElroy SL, Nolen WA, Kupka R, Grunze H, Walden J, Rowe M. PMID: 21178634.
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    334. Clinical practice. Bipolar disorder--a focus on depression. N Engl J Med. 2011 Jan 06; 364(1):51-9. Frye MA. PMID: 21208108.
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    335. Utilization of residential alcoholism treatment in bipolar disorder. Am J Addict. 2011 Jan-Feb; 20(1):40-4. Hall-Flavin DK, Schneekloth TD, Loukianova LL, Karpyak VM, Lesnick TG, Biernacka JM, Mrazek DA, Frye MA. PMID: 21175919.
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    336. Complexity of pharmacologic treatment required for sustained improvement in outpatients with bipolar disorder. J Clin Psychiatry. 2010 Sep; 71(9):1176-86; quiz 1252-3. Post RM, Altshuler LL, Frye MA, Suppes T, Keck PE, McElroy SL, Leverich GS, Luckenbaugh DA, Rowe M, Pizzarello S, Kupka RW, Grunze H, Nolen WA. PMID: 20923622.
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    337. Improving the design of maintenance studies for bipolar disorder. Curr Med Res Opin. 2010 Aug; 26(8):1835-42. Gitlin MJ, Abulseoud O, Frye MA. PMID: 20515320.
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    338. Prevalence and correlates of eating disorders in 875 patients with bipolar disorder. J Affect Disord. 2011 Feb; 128(3):191-8. McElroy SL, Frye MA, Hellemann G, Altshuler L, Leverich GS, Suppes T, Keck PE, Nolen WA, Kupka R, Post RM. PMID: 20674033.
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    339. Adjunctive armodafinil for major depressive episodes associated with bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept study. J Clin Psychiatry. 2010 Oct; 71(10):1363-70. Calabrese JR, Ketter TA, Youakim JM, Tiller JM, Yang R, Frye MA. PMID: 20673554.
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    340. Theta motion processing in fruit flies. Front Behav Neurosci. 2010; 4. Theobald JC, Shoemaker PA, Ringach DL, Frye MA. PMID: 20700393; PMCID: PMC2918350.
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    342. Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood. J Clin Psychiatry. 2010 Jul; 71(7):864-72. Post RM, Leverich GS, Kupka RW, Keck PE, McElroy SL, Altshuler LL, Frye MA, Luckenbaugh DA, Rowe M, Grunze H, Suppes T, Nolen WA. PMID: 20667291.
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    343. Mutation of the Drosophila vesicular GABA transporter disrupts visual figure detection. J Exp Biol. 2010 May; 213(Pt 10):1717-30. Fei H, Chow DM, Chen A, Romero-Calderón R, Ong WS, Ackerson LC, Maidment NT, Simpson JH, Frye MA, Krantz DE. PMID: 20435823; PMCID: PMC2861964.
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    344. Dynamics of optomotor responses in Drosophila to perturbations in optic flow. J Exp Biol. 2010 Apr; 213(Pt 8):1366-75. Theobald JC, Ringach DL, Frye MA. PMID: 20348349; PMCID: PMC2846167.
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    345. Mechanisms of odor-tracking: multiple sensors for enhanced perception and behavior. Front Cell Neurosci. 2010; 4:6. Gomez-Marin A, Duistermars BJ, Frye MA, Louis M. PMID: 20407585; PMCID: PMC2854573.
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    348. Modafinil for bipolar depression with comorbid methamphetamine abuse. Am J Addict. 2010 Mar-Apr; 19(2):190-1. Camacho A, Ng B, Frye MA. PMID: 20163392.
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    349. Multisensory integration for odor tracking by flying Drosophila: Behavior, circuits and speculation. Commun Integr Biol. 2010 Jan; 3(1):60-3. Duistermars BJ, Frye MA. PMID: 20539786; PMCID: PMC2881244.
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    352. Olanzapine/fluoxetine combination for the treatment of mixed depression in bipolar I disorder: a post hoc analysis. J Clin Psychiatry. 2009 Oct; 70(10):1424-31. Benazzi F, Berk M, Frye MA, Wang W, Barraco A, Tohen M. PMID: 19906346.
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    353. Mood stabilization and destabilization during acute and continuation phase treatment for bipolar I disorder with lamotrigine or placebo. J Clin Psychiatry. 2009 Sep; 70(9):1273-80. Goldberg JF, Calabrese JR, Saville BR, Frye MA, Ketter TA, Suppes T, Post RM, Goodwin FK. PMID: 19689918.
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    354. Neurogenetics and the "fly-stampede": dissecting neural circuits involved in visual behaviors. Fly (Austin). 2009 Jul-Sep; 3(3):207-9. Zhu Y, Frye M. PMID: 19625763.
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    355. Flies require bilateral sensory input to track odor gradients in flight. Curr Biol. 2009 Aug 11; 19(15):1301-7. Duistermars BJ, Chow DM, Frye MA. PMID: 19576769; PMCID: PMC2726901.
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    356. Disrupting disordered neurocircuitry: treating refractory psychiatric illness with neuromodulation. Mayo Clin Proc. 2009 Jun; 84(6):522-32. Tye SJ, Frye MA, Lee KH. PMID: 19483169; PMCID: PMC2688626.
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    357. Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study. J Clin Psychiatry. 2009 Apr; 70(4):450-7. Altshuler LL, Post RM, Hellemann G, Leverich GS, Nolen WA, Frye MA, Keck PE, Kupka RW, Grunze H, McElroy SL, Sugar CA, Suppes T. PMID: 19358785.
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    358. Peripheral visual circuits functionally segregate motion and phototaxis behaviors in the fly. Curr Biol. 2009 Apr 14; 19(7):613-9. Zhu Y, Nern A, Zipursky SL, Frye MA. PMID: 19303299; PMCID: PMC2846117.
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    359. Invertebrate solutions for sensing gravity. Curr Biol. 2009 Mar 10; 19(5):R186-90. Bender JA, Frye MA. PMID: 19278626.
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    360. Depressive relapse during lithium treatment associated with increased serum thyroid-stimulating hormone: results from two placebo-controlled bipolar I maintenance studies. Acta Psychiatr Scand. 2009 Jul; 120(1):10-3. Frye MA, Yatham L, Ketter TA, Goldberg J, Suppes T, Calabrese JR, Bowden CL, Bourne E, Bahn RS, Adams B. PMID: 19183414.
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    361. Visually mediated odor tracking during flight in Drosophila. J Vis Exp. 2009 Jan 26; (23). Frye MA, Duistermars BJ. PMID: 19229181; PMCID: PMC2781825.
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    362. The neuro-ecology of resource localization in Drosophila: behavioral components of perception and search. Fly (Austin). 2009 Jan-Mar; 3(1):50-61. Chow DM, Frye MA. PMID: 19218831.
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    363. The psychometric validation of the Sheehan Disability Scale (SDS) in patients with bipolar disorder. Psychiatry Res. 2009 Jan 30; 165(1-2):163-74. Arbuckle R, Frye MA, Brecher M, Paulsson B, Rajagopalan K, Palmer S, Degl' Innocenti A. PMID: 19042030.
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    364. A magnetic tether system to investigate visual and olfactory mediated flight control in Drosophila. J Vis Exp. 2008 Nov 21; (21). Duistermars BJ, Frye M. PMID: 19066526; PMCID: PMC2953965.
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    365. Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression. Am J Psychiatry. 2009 Feb; 166(2):164-72. Frye MA, Helleman G, McElroy SL, Altshuler LL, Black DO, Keck PE, Nolen WA, Kupka R, Leverich GS, Grunze H, Mintz J, Post RM, Suppes T. PMID: 19015231.
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    366. Context-dependent olfactory enhancement of optomotor flight control in Drosophila. J Exp Biol. 2008 Aug; 211(Pt 15):2478-85. Chow DM, Frye MA. PMID: 18626082.
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    367. Flies see second-order motion. Curr Biol. 2008 Jun 03; 18(11):R464-5. Theobald JC, Duistermars BJ, Ringach DL, Frye MA. PMID: 18522814.
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    368. Diagnostic dilemmas and clinical correlates of mixed states in bipolar disorder. J Clin Psychiatry. 2008 May; 69(5):e13. Frye MA. PMID: 18681758.
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    369. Are bipolar mood symptoms affected by the phase of the menstrual cycle? J Womens Health (Larchmt). 2008 Apr; 17(3):473-8. Shivakumar G, Bernstein IH, Suppes T, Stanley Foundation Bipolar Network, Keck PE, McElroy SL, Altshuler LL, Frye MA, Nolen WA, Kupka RW, Grunze H, Leverich GS, Mintz J, Post RM. PMID: 18328012.
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    370. Aripiprazole efficacy in irritability and disruptive-aggressive symptoms: young mania rating scale line analysis from two, randomized, double-blind, placebo-controlled trials. J Clin Psychopharmacol. 2008 Apr; 28(2):243-5. Frye MA, Eudicone J, Pikalov A, McQuade RD, Marcus RN, Carlson BX. PMID: 18344741.
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    371. Animal behavior: flying back to front. Curr Biol. 2008 Feb 26; 18(4):R169-70. Theobald JC, Frye MA. PMID: 18302921.
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    372. Crossmodal visual input for odor tracking during fly flight. Curr Biol. 2008 Feb 26; 18(4):270-5. Duistermars BJ, Frye MA. PMID: 18280156.
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    373. Incidence of childhood-onset bipolar illness in the USA and Europe. Br J Psychiatry. 2008 Feb; 192(2):150-1. Post RM, Luckenbaugh DA, Leverich GS, Altshuler LL, Frye MA, Suppes T, Keck PE, McElroy SL, Nolen WA, Kupka R, Grunze H, Walden J. PMID: 18245035.
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    374. The alcohol withdrawal syndrome. J Neurol Neurosurg Psychiatry. 2008 Aug; 79(8):854-62. McKeon A, Frye MA, Delanty N. PMID: 17986499.
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    375. Bipolar depression: best practices for the hospitalized patient. CNS Spectr. 2007 Nov; 12(11 Suppl 19):1-13. Keck PE, Frye MA, Thase ME. PMID: 17984859.
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    376. Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment Network. Int Clin Psychopharmacol. 2007 Nov; 22(6):376-81. Suppes T, Kelly DI, Keck PE, McElroy SL, Altshuler LL, Mintz J, Frye MA, Nolen WA, Luckenbaugh DA, Post RM, Leverich GS, Kupka RW, Grunze H. PMID: 17917557.
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    377. Routine stair climbing in place of residence and body mass index: a pan-European population based study. Int J Obes (Lond). 2008 Mar; 32(3):490-4. Shenassa ED, Frye M, Braubach M, Daskalakis C. PMID: 17955028.
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    378. The spatial, temporal and contrast properties of expansion and rotation flight optomotor responses in Drosophila. J Exp Biol. 2007 Sep; 210(Pt 18):3218-27. Duistermars BJ, Chow DM, Condro M, Frye MA. PMID: 17766299.
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    379. A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression. Am J Psychiatry. 2007 Aug; 164(8):1242-9. Frye MA, Grunze H, Suppes T, McElroy SL, Keck PE, Walden J, Leverich GS, Altshuler LL, Nakelsky S, Hwang S, Mintz J, Post RM. PMID: 17671288.
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    380. Comorbid substance use disorder in women with bipolar disorder associated with criminal arrest. Bipolar Disord. 2007 Aug; 9(5):536-40. McDermott BE, Quanbeck CD, Frye MA. PMID: 17680926.
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    381. Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder. Bipolar Disord. 2007 Aug; 9(5):531-5. Kupka RW, Altshuler LL, Nolen WA, Suppes T, Luckenbaugh DA, Leverich GS, Frye MA, Keck PE, McElroy SL, Grunze H, Post RM. PMID: 17680925.
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    382. Modal subcomponents of metabolic syndrome in patients with bipolar disorder. J Affect Disord. 2008 Feb; 106(1-2):91-7. Cardenas J, Frye MA, Marusak SL, Levander EM, Chirichigno JW, Lewis S, Nakelsky S, Hwang S, Mintz J, Altshuler LL. PMID: 17628693.
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    383. Dynamic properties of large-field and small-field optomotor flight responses in Drosophila. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2007 Jul; 193(7):787-99. Duistermars BJ, Reiser MB, Zhu Y, Frye MA. PMID: 17551735.
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    384. Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling bipolar disorder. Biol Psychiatry. 2008 Jan 01; 63(1):125-30. Goldberg JF, Bowden CL, Calabrese JR, Ketter TA, Dann RS, Frye MA, Suppes T, Post RM. PMID: 17543894.
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    385. Lack of mania prophylaxis associated with lamotrigine monotherapy in manic-predominant bipolar I disorder. J Clin Psychiatry. 2007 Jun; 68(6):973-4. Dossett EC, Land AJ, Gitlin MJ, Frye MA. PMID: 17592931.
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    386. A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders. Bipolar Disord. 2007 Jun; 9(4):426-34. McElroy SL, Frye MA, Altshuler LL, Suppes T, Hellemann G, Black D, Mintz J, Kupka R, Nolen W, Leverich GS, Denicoff KD, Post RM, Keck PE. PMID: 17547588.
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    387. Visual edge orientation shapes free-flight behavior in Drosophila. Fly (Austin). 2007 May-Jun; 1(3):153-4. Frye MA, Dickinson MH. PMID: 18820449.
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    388. The poor prognosis of childhood-onset bipolar disorder. J Pediatr. 2007 May; 150(5):485-90. Leverich GS, Post RM, Keck PE, Altshuler LL, Frye MA, Kupka RW, Nolen WA, Suppes T, McElroy SL, Grunze H, Denicoff K, Moravec MK, Luckenbaugh D. PMID: 17452221.
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    389. Tranylcypromine vs. lamotrigine in the treatment of refractory bipolar depression: a failed but clinically useful study. Acta Psychiatr Scand. 2007 May; 115(5):360-5. Nolen WA, Kupka RW, Hellemann G, Frye MA, Altshuler LL, Leverich GS, Suppes T, Keck PE, McElroy S, Grunze H, Mintz J, Post RM. PMID: 17430413.
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    390. Increased anterior cingulate/medial prefrontal cortical glutamate and creatine in bipolar depression. Neuropsychopharmacology. 2007 Dec; 32(12):2490-9. Frye MA, Watzl J, Banakar S, O'Neill J, Mintz J, Davanzo P, Fischer J, Chirichigno JW, Ventura J, Elman S, Tsuang J, Walot I, Thomas MA. PMID: 17429412.
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    391. Free-flight odor tracking in Drosophila is consistent with an optimal intermittent scale-free search. PLoS One. 2007 Apr 04; 2(4):e354. Reynolds AM, Frye MA. PMID: 17406678; PMCID: PMC1831497.
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    394. Behavioral neurobiology: a vibrating gyroscope controls fly steering maneuvers. Curr Biol. 2007 Feb 20; 17(4):R134-6. Frye MA. PMID: 17307048.
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    397. Defining the clinical course of bipolar disorder: response, remission, relapse, recurrence, and roughening. Psychopharmacol Bull. 2007; 40(3):7-14. Hirschfeld RM, Calabrese JR, Frye MA, Lavori PW, Sachs G, Thase ME, Wagner KD. PMID: 18007564.
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    398. Bipolar disorder and comorbid alcoholism: prevalence rate and treatment considerations. Bipolar Disord. 2006 Dec; 8(6):677-85. Frye MA, Salloum IM. PMID: 17156154.
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    399. New findings from the Bipolar Collaborative Network: clinical implications for therapeutics. Curr Psychiatry Rep. 2006 Dec; 8(6):489-97. Post RM, Altshuler LL, Frye MA, Suppes T, McElroy S, Keck PE, Leverich GS, Kupka R, Nolen WA, Grunze H. PMID: 17162830.
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    400. Free T4 index and clinical outcome in patients with depression. J Affect Disord. 2007 Jun; 100(1-3):271-7. Abulseoud O, Sane N, Cozzolino A, Kiriakos L, Mehra V, Gitlin M, Masseling S, Whybrow P, Altshuler LL, Mintz J, Frye MA. PMID: 17123630.
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    401. Incidence and time course of subsyndromal symptoms in patients with bipolar I disorder: an evaluation of 2 placebo-controlled maintenance trials. J Clin Psychiatry. 2006 Nov; 67(11):1721-8. Frye MA, Yatham LN, Calabrese JR, Bowden CL, Ketter TA, Suppes T, Adams BE, Thompson TR. PMID: 17196051.
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    402. Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite study. J Clin Psychiatry. 2006 Oct; 67(10):1551-60. Altshuler LL, Post RM, Black DO, Keck PE, Nolen WA, Frye MA, Suppes T, Grunze H, Kupka RW, Leverich GS, McElroy SL, Walden J, Mintz J. PMID: 17107246.
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    403. Healthcare resource utilization in bipolar depression compared with unipolar depression: results of a United States population-based study. CNS Spectr. 2006 Sep; 11(9):704-10; quiz 719. Frye MA, Calabrese JR, Reed ML, Hirschfeld RM. PMID: 16946695.
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    404. Predictors of bipolar disorder risk among patients currently treated for major depression. MedGenMed. 2006 Aug 15; 8(3):38. Calabrese JR, Muzina DJ, Kemp DE, Sachs GS, Frye MA, Thompson TR, Klingman D, Reed ML, Hirschfeld RM. PMID: 17406171; PMCID: PMC1781328.
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    405. Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline. Br J Psychiatry. 2006 Aug; 189:124-31. Post RM, Altshuler LL, Leverich GS, Frye MA, Nolen WA, Kupka RW, Suppes T, McElroy S, Keck PE, Denicoff KD, Grunze H, Walden J, Kitchen CM, Mintz J. PMID: 16880481.
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    406. Discharge against medical advice from inpatient psychiatric treatment: a literature review. Psychiatr Serv. 2006 Aug; 57(8):1192-8. Brook M, Hilty DM, Liu W, Hu R, Frye MA. PMID: 16870972.
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    407. Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder. Biol Psychiatry. 2006 Nov 01; 60(9):1020-2. Keck PE, Mintz J, McElroy SL, Freeman MP, Suppes T, Frye MA, Altshuler LL, Kupka R, Nolen WA, Leverich GS, Denicoff KD, Grunze H, Duan N, Post RM. PMID: 16814257.
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    408. Low cerebrospinal fluid glutamate and glycine in refractory affective disorder. Biol Psychiatry. 2007 Jan 15; 61(2):162-6. Frye MA, Tsai GE, Huggins T, Coyle JT, Post RM. PMID: 16735030.
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    409. Recurrence in bipolar I disorder: a post hoc analysis excluding relapses in two double-blind maintenance studies. Biol Psychiatry. 2006 Jun 01; 59(11):1061-4. Calabrese JR, Goldberg JF, Ketter TA, Suppes T, Frye M, White R, DeVeaugh-Geiss A, Thompson TR. PMID: 16769295.
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    410. Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizers. Am J Psychiatry. 2006 Feb; 163(2):232-9. Leverich GS, Altshuler LL, Frye MA, Suppes T, McElroy SL, Keck PE, Kupka RW, Denicoff KD, Nolen WA, Grunze H, Martinez MI, Post RM. PMID: 16449476.
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    411. Lower switch rate in depressed patients with bipolar II than bipolar I disorder treated adjunctively with second-generation antidepressants. Am J Psychiatry. 2006 Feb; 163(2):313-5. Altshuler LL, Suppes T, Black DO, Nolen WA, Leverich G, Keck PE, Frye MA, Kupka R, McElroy SL, Grunze H, Kitchen CM, Post R. PMID: 16449487.
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    412. Use of health care services among persons who screen positive for bipolar disorder. Psychiatr Serv. 2005 Dec; 56(12):1529-33. Frye MA, Calabrese JR, Reed ML, Wagner KD, Lewis L, McNulty J, Hirschfeld RM. PMID: 16339614.
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    413. Clinical and legal characteristics of inmates with bipolar disorder. Curr Psychiatry Rep. 2005 Dec; 7(6):478-84. Quanbeck CD, McDermott BE, Frye MA. PMID: 16318827.
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    414. Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon. Arch Gen Psychiatry. 2005 Oct; 62(10):1089-96. Suppes T, Mintz J, McElroy SL, Altshuler LL, Kupka RW, Frye MA, Keck PE, Nolen WA, Leverich GS, Grunze H, Rush AJ, Post RM. PMID: 16203954.
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    415. Longitudinal evaluation of reproductive function in women treated for bipolar disorder. J Affect Disord. 2005 Dec; 89(1-3):217-25. Rasgon NL, Reynolds MF, Elman S, Saad M, Frye MA, Bauer M, Altshuler LL. PMID: 16171873.
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    416. Patterns of alcohol consumption in bipolar patients comorbid for alcohol abuse or dependence. Bipolar Disord. 2005 Aug; 7(4):377-81. McKowen JW, Frye MA, Altshuler LL, Gitlin MJ. PMID: 16026491.
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    417. Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients. Am J Psychiatry. 2005 Jul; 162(7):1273-80. Kupka RW, Luckenbaugh DA, Post RM, Suppes T, Altshuler LL, Keck PE, Frye MA, Denicoff KD, Grunze H, Leverich GS, McElroy SL, Walden J, Nolen WA. PMID: 15994709.
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    418. Relationship between criminal arrest and community treatment history among patients with bipolar disorder. Psychiatr Serv. 2005 Jul; 56(7):847-52. Quanbeck CD, Stone DC, McDermott BE, Boone K, Scott CL, Frye MA. PMID: 16020818.
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    419. Reproductive function and risk for PCOS in women treated for bipolar disorder. Bipolar Disord. 2005 Jun; 7(3):246-59. Rasgon NL, Altshuler LL, Fairbanks L, Elman S, Bitran J, Labarca R, Saad M, Kupka R, Nolen WA, Frye MA, Suppes T, McElroy SL, Keck PE, Leverich G, Grunze H, Walden J, Post R, Mintz J. PMID: 15898962.
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    420. Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trial. J Clin Psychiatry. 2005 May; 66(5):617-24. McElroy SL, Suppes T, Keck PE, Black D, Frye MA, Altshuler LL, Nolen WA, Kupka RW, Leverich GS, Walden J, Grunze H, Post RM. PMID: 15889949.
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    421. Supraphysiological doses of levothyroxine alter regional cerebral metabolism and improve mood in bipolar depression. Mol Psychiatry. 2005 May; 10(5):456-69. Bauer M, London ED, Rasgon N, Berman SM, Frye MA, Altshuler LL, Mandelkern MA, Bramen J, Voytek B, Woods R, Mazziotta JC, Whybrow PC. PMID: 15724143.
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    422. Preliminary observations on the effectiveness of levetiracetam in the open adjunctive treatment of refractory bipolar disorder. J Clin Psychiatry. 2005 Mar; 66(3):370-4. Post RM, Altshuler LL, Frye MA, Suppes T, McElroy SL, Keck PE, Leverich GS, Kupka R, Nolen WA, Luckenbaugh DA, Walden J, Grunze H. PMID: 15766304.
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    423. Molecular dynamics of cyclically contracting insect flight muscle in vivo. Nature. 2005 Jan 20; 433(7023):330-4. Dickinson M, Farman G, Frye M, Bekyarova T, Gore D, Maughan D, Irving T. PMID: 15662427.
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    424. Closing the loop between neurobiology and flight behavior in Drosophila. Curr Opin Neurobiol. 2004 Dec; 14(6):729-36. Frye MA, Dickinson MH. PMID: 15582376.
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    425. Impact of depressive symptoms compared with manic symptoms in bipolar disorder: results of a U.S. community-based sample. J Clin Psychiatry. 2004 Nov; 65(11):1499-504. Calabrese JR, Hirschfeld RM, Frye MA, Reed ML. PMID: 15554762.
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    426. Peripheral thyroid hormones and response to selective serotonin reuptake inhibitors. J Psychiatry Neurosci. 2004 Sep; 29(5):383-6. Gitlin M, Altshuler LL, Frye MA, Suri R, Huynh EL, Fairbanks L, Bauer M, Korenman S. PMID: 15486607; PMCID: PMC518867.
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    427. Chart review of the impact of attention-deficit/hyperactivity disorder comorbidity on response to lithium or divalproex sodium in adolescent mania. J Clin Psychiatry. 2004 Aug; 65(8):1057-63. State RC, Frye MA, Altshuler LL, Strober M, DeAntonio M, Hwang S, Mintz J. PMID: 15323589.
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    428. Correlates of 1-year prospective outcome in bipolar disorder: results from the Stanley Foundation Bipolar Network. Am J Psychiatry. 2004 Aug; 161(8):1447-54. Nolen WA, Luckenbaugh DA, Altshuler LL, Suppes T, McElroy SL, Frye MA, Kupka RW, Keck PE, Leverich GS, Post RM. PMID: 15285972.
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    429. Use of quetiapine in bipolar disorder: a case series with prospective evaluation. Int Clin Psychopharmacol. 2004 May; 19(3):173-4. Suppes T, McElroy SL, Keck PE, Altshuler L, Frye MA, Grunze H, Leverich GS, Nolen WA, Chisholm K, Dennehy EB, Post RM. PMID: 15107662.
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    430. Clinical and legal correlates of inmates with bipolar disorder at time of criminal arrest. J Clin Psychiatry. 2004 Feb; 65(2):198-203. Quanbeck CD, Stone DC, Scott CL, McDermott BE, Altshuler LL, Frye MA. PMID: 15003073.
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    431. Spatial organization of visuomotor reflexes in Drosophila. J Exp Biol. 2004 Jan; 207(Pt 1):113-22. Tammero LF, Frye MA, Dickinson MH. PMID: 14638838.
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    432. Motor output reflects the linear superposition of visual and olfactory inputs in Drosophila. J Exp Biol. 2004 Jan; 207(Pt 1):123-31. Frye MA, Dickinson MH. PMID: 14638839.
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    433. Unmet needs in bipolar depression. Depress Anxiety. 2004; 19(4):199-208. Frye MA, Gitlin MJ, Altshuler LL. PMID: 15274168.
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    434. A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network. Bipolar Disord. 2003 Dec; 5(6):396-406. Post RM, Leverich GS, Nolen WA, Kupka RW, Altshuler LL, Frye MA, Suppes T, McElroy S, Keck P, Grunze H, Walden J, Stanley Foundation Bipolar Network. PMID: 14636363.
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    435. An overview of recent findings of the Stanley Foundation Bipolar Network (Part I). Bipolar Disord. 2003 Oct; 5(5):310-9. Post RM, Leverich GS, Altshuler LL, Frye MA, Suppes TM, Keck PE, McElroy SL, Kupka R, Nolen WA, Grunze H, Walden J. PMID: 14525551.
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    436. Mania and the law in California: understanding the criminalization of the mentally ill. Am J Psychiatry. 2003 Jul; 160(7):1245-50. Quanbeck C, Frye M, Altshuler L. PMID: 12832237.
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    437. Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up. Am J Psychiatry. 2003 Jul; 160(7):1252-62. Altshuler L, Suppes T, Black D, Nolen WA, Keck PE, Frye MA, McElroy S, Kupka R, Grunze H, Walden J, Leverich G, Denicoff K, Luckenbaugh D, Post R. PMID: 12832239.
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    438. Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study. Am J Psychiatry. 2003 Jul; 160(7):1263-71. Tohen M, Ketter TA, Zarate CA, Suppes T, Frye M, Altshuler L, Zajecka J, Schuh LM, Risser RC, Brown E, Baker RW. PMID: 12832240.
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    439. Psychosis in bipolar disorder: phenomenology and impact on morbidity and course of illness. Compr Psychiatry. 2003 Jul-Aug; 44(4):263-9. Keck PE, McElroy SL, Havens JR, Altshuler LL, Nolen WA, Frye MA, Suppes T, Denicoff KD, Kupka R, Leverich GS, Rush AJ, Post RM. PMID: 12923703.
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    440. Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH life chart method. J Clin Psychiatry. 2003 Jun; 64(6):680-90; quiz 738-9. Post RM, Denicoff KD, Leverich GS, Altshuler LL, Frye MA, Suppes TM, Rush AJ, Keck PE, McElroy SL, Luckenbaugh DA, Pollio C, Kupka R, Nolen WA. PMID: 12823083.
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    441. A signature of salience in the Drosophila brain. Nat Neurosci. 2003 Jun; 6(6):544-6. Frye MA, Dickinson MH. PMID: 12771957.
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    442. Neuronal pathology in the hippocampal area of patients with bipolar disorder: a study with proton magnetic resonance spectroscopic imaging. Biol Psychiatry. 2003 May 15; 53(10):906-13. Bertolino A, Frye M, Callicott JH, Mattay VS, Rakow R, Shelton-Repella J, Post R, Weinberger DR. PMID: 12742678.
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    443. Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network. J Clin Psychiatry. 2003 May; 64(5):506-15. Leverich GS, Altshuler LL, Frye MA, Suppes T, Keck PE, McElroy SL, Denicoff KD, Obrocea G, Nolen WA, Kupka R, Walden J, Grunze H, Perez S, Luckenbaugh DA, Post RM. PMID: 12755652.
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    444. Gender differences in prevalence, risk, and clinical correlates of alcoholism comorbidity in bipolar disorder. Am J Psychiatry. 2003 May; 160(5):883-9. Frye MA, Altshuler LL, McElroy SL, Suppes T, Keck PE, Denicoff K, Nolen WA, Kupka R, Leverich GS, Pollio C, Grunze H, Walden J, Post RM. PMID: 12727691.
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    445. Acceleration and augmentation strategies for treating bipolar depression. Biol Psychiatry. 2003 Apr 15; 53(8):691-700. Altshuler LL, Frye MA, Gitlin MJ. PMID: 12706955.
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    446. Impact of bipolar disorder on a U.S. community sample. J Clin Psychiatry. 2003 Apr; 64(4):425-32. Calabrese JR, Hirschfeld RM, Reed M, Davies MA, Frye MA, Keck PE, Lewis L, McElroy SL, McNulty JP, Wagner KD. PMID: 12716245.
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    447. Odor localization requires visual feedback during free flight in Drosophila melanogaster. J Exp Biol. 2003 Mar; 206(Pt 5):843-55. Frye MA, Tarsitano M, Dickinson MH. PMID: 12547939.
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    448. Treating acute mania. J Fam Pract. 2003 Mar; Suppl:S10-3. Frye MA, Gitlin MJ, Altshuler LL. PMID: 12676078.
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    449. Low CSF somatostatin associated with response to nimodipine in patents with affective illness. Biol Psychiatry. 2003 Jan 15; 53(2):180-3. Frye MA, Pazzaglia PJ, George MS, Luckenbaugh DA, Vanderham E, Davis CL, Rubinow DR, Post RM. PMID: 12547475.
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    450. Screening for bipolar disorder in the community. J Clin Psychiatry. 2003 Jan; 64(1):53-9. Hirschfeld RM, Calabrese JR, Weissman MM, Reed M, Davies MA, Frye MA, Keck PE, Lewis L, McElroy SL, McNulty JP, Wagner KD. PMID: 12590624.
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    451. Validity of the mood disorder questionnaire: a general population study. Am J Psychiatry. 2003 Jan; 160(1):178-80. Hirschfeld RM, Holzer C, Calabrese JR, Weissman M, Reed M, Davies M, Frye MA, Keck P, McElroy S, Lewis L, Tierce J, Wagner KD, Hazard E. PMID: 12505821.
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    452. Acute antimanic efficacy and safety of oxcarbazepine in an open trial with an on-off-on design. Bipolar Disord. 2002 Dec; 4(6):412-7. Hummel B, Walden J, Stampfer R, Dittmann S, Amann B, Sterr A, Schaefer M, Frye MA, Grunze H. PMID: 12519102.
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    453. Tiagabine in treatment refractory bipolar disorder: a clinical case series. Bipolar Disord. 2002 Oct; 4(5):283-9. Suppes T, Chisholm KA, Dhavale D, Frye MA, Altshuler LL, McElroy SL, Keck PE, Nolen WA, Kupka R, Denicoff KD, Leverich GS, Rush AJ, Post RM. PMID: 12479659.
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    454. Mania and attention deficit hyperactivity disorder in a prepubertal child: diagnostic and treatment challenges. Am J Psychiatry. 2002 Jun; 159(6):918-25. State RC, Altshuler LL, Frye MA. PMID: 12042177.
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