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Alcino Jose Silva

Title(s)Professor, Neurobiology
SchoolMedicine
Address760 Westwood Plaza 73-210
Los Angeles CA 90024
Phone46345
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    Other Positions
    Title(s)Professor, Psychiatry and Biobehavioral Sciences


    Collapse Research 
    Collapse Research Activities and Funding
    CCR5 Activation and Cognitive Dysfunction Caused by HIV-Proteins
    NIH/NINDS R01NS106969Sep 30, 2017 - May 31, 2022
    Role: Principal Investigator
    Molecular, Cellular and Circuit Mechnisms for Memory-linking deficits in Psychiatric Disorders
    NIH/NIMH R01MH113071Jun 1, 2017 - May 31, 2022
    Role: Principal Investigator
    Building and sharing next generation open-source, wireless, multichannel miniaturized microscopes for imaging activity in freely behaving mice
    NIH/NINDS U01NS094286Sep 30, 2015 - Jun 30, 2018
    Role: Co-Principal Investigator
    Forward Genetic Approaches to Mechanisms of Cortical Plasticity
    NIH/NIMH P50MH077972Apr 1, 2007 - Mar 31, 2012
    Role: Principal Investigator
    Molecular and Cellular Cognition Meeting
    NIH/NIMH R13MH073327Sep 22, 2004 - Jul 31, 2007
    Role: Principal Investigator
    AGE RELATED LEARNING AND MEMORY IMPROVEMENTS
    NIH/NIA R01AG017499Mar 1, 2000 - Feb 28, 2005
    Role: Principal Investigator
    PHENOTYPING THE MOUSE NERVOUS SYSTEM AND BEHAVIOR
    NIH/NIMH R01MH061094Dec 6, 1999 - Nov 30, 2002
    Role: Principal Investigator
    Mechanisms for Cognitive Dysfunction in Noonan Syndrome
    NIH/NIMH R01MH084315Sep 4, 1998 - Nov 30, 2020
    Role: Principal Investigator
    Mechanisms for Neurological Dysfunction in NF1
    NIH/NINDS R01NS038480Sep 4, 1998 - Feb 28, 2003
    Role: Principal Investigator
    Gene Targeting Approaches to Learning and Memory Studies
    NIH/NIA R37AG013622Jul 25, 1995 - Mar 31, 2017
    Role: Principal Investigator
    Molecular, cellular and circuit mechanisms for age-related deficits in memory-linking
    NIH/NIA R01AG013622Jul 25, 1995 - Jun 30, 2000
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Getting the full picture. Elife. 2019 03 26; 8. Luchetti A, Chowdhury A, Silva AJ. PMID: 30912744.
      View in: PubMed   Mentions:    Fields:    
    2. Excitatory neuron-specific SHP2-ERK signaling network regulates synaptic plasticity and memory. Sci Signal. 2019 03 05; 12(571). Ryu HH, Kim T, Kim JW, Kang M, Park P, Kim YG, Kim H, Ha J, Choi JE, Lee J, Lim CS, Kim CH, Kim SJ, Silva AJ, Kaang BK, Lee YS. PMID: 30837304.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    3. CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury. Cell. 2019 02 21; 176(5):1143-1157.e13. Joy MT, Ben Assayag E, Shabashov-Stone D, Liraz-Zaltsman S, Mazzitelli J, Arenas M, Abduljawad N, Kliper E, Korczyn AD, Thareja NS, Kesner EL, Zhou M, Huang S, Silva TK, Katz N, Bornstein NM, Silva AJ, Shohami E, Carmichael ST. PMID: 30794775.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    4. All the light that we can see: a new era in miniaturized microscopy. Nat Methods. 2019 Jan; 16(1):11-13. Aharoni D, Khakh BS, Silva AJ, Golshani P. PMID: 30573833.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    5. ResearchMaps.org for integrating and planning research. PLoS One. 2018; 13(5):e0195271. Matiasz NJ, Wood J, Doshi P, Speier W, Beckemeyer B, Wang W, Hsu W, Silva AJ. PMID: 29723213.
      View in: PubMed   Mentions: 1     Fields:    
    6. Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability. Nat Neurosci. 2018 03; 21(3):309-314. Lisman J, Cooper K, Sehgal M, Silva AJ. PMID: 29434376.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    7. Hotspots of dendritic spine turnover facilitate clustered spine addition and learning and memory. Nat Commun. 2018 01 29; 9(1):422. Frank AC, Huang S, Zhou M, Gdalyahu A, Kastellakis G, Silva TK, Lu E, Wen X, Poirazi P, Trachtenberg JT, Silva AJ. PMID: 29379017.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    8. Miniaturized two-photon microscope: seeing clearer and deeper into the brain. Light Sci Appl. 2017 Aug; 6(8):e17104. Silva AJ. PMID: 30167288.
      View in: PubMed   Mentions:
    9. Risky Decision Making in Neurofibromatosis Type 1: An Exploratory Study. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Mar; 2(2):170-179. Jonas RK, Roh E, Montojo CA, Pacheco LA, Rosser T, Silva AJ, Bearden CE. PMID: 28736755.
      View in: PubMed   Mentions: 2     Fields:    
    10. CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory. Elife. 2016 12 20; 5. Zhou M, Greenhill S, Huang S, Silva TK, Sano Y, Wu S, Cai Y, Nagaoka Y, Sehgal M, Cai DJ, Lee YS, Fox K, Silva AJ. PMID: 27996938.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    11. Randomized placebo-controlled study of lovastatin in children with neurofibromatosis type 1. Neurology. 2016 Dec 13; 87(24):2575-2584. Payne JM, Barton B, Ullrich NJ, Cantor A, Hearps SJ, Cutter G, Rosser T, Walsh KS, Gioia GA, Wolters PL, Tonsgard J, Schorry E, Viskochil D, Klesse L, Fisher M, Gutmann DH, Silva AJ, Hunter SJ, Rey-Casserly C, Cantor NL, Byars AW, Stavinoha PL, Ackerson JD, Armstrong CL, Isenberg J, O'Neil SH, Packer RJ, Korf B, Acosta MT, North KN. PMID: 27956565.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    12. Corrigendum: The need for novel informatics tools for integrating and planning research in molecular and cellular cognition. Learn Mem. 2016 11; 23(11):668. Silva AJ, Müller KR. PMID: 27918288.
      View in: PubMed   Mentions:    Fields:    
    13. Molecular and Cellular Mechanisms for Trapping and Activating Emotional Memories. PLoS One. 2016; 11(8):e0161655. Rogerson T, Jayaprakash B, Cai DJ, Sano Y, Lee YS, Zhou Y, Bekal P, Deisseroth K, Silva AJ. PMID: 27579481.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    14. A shared neural ensemble links distinct contextual memories encoded close in time. Nature. 2016 06 02; 534(7605):115-8. Cai DJ, Aharoni D, Shuman T, Shobe J, Biane J, Song W, Wei B, Veshkini M, La-Vu M, Lou J, Flores SE, Kim I, Sano Y, Zhou M, Baumgaertel K, Lavi A, Kamata M, Tuszynski M, Mayford M, Golshani P, Silva AJ. PMID: 27251287.
      View in: PubMed   Mentions: 124     Fields:    Translation:AnimalsCells
    15. Hijacking translation in addiction. Elife. 2016 Mar 01; 5. Izquierdo A, Silva AJ. PMID: 26929992.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. A randomized placebo-controlled lovastatin trial for neurobehavioral function in neurofibromatosis I. Ann Clin Transl Neurol. 2016 04; 3(4):266-79. Bearden CE, Hellemann GS, Rosser T, Montojo C, Jonas R, Enrique N, Pacheco L, Hussain SA, Wu JY, Ho JS, McGough JJ, Sugar CA, Silva AJ. PMID: 27081657.
      View in: PubMed   Mentions: 16     Fields:    
    17. Resting state functional MRI reveals abnormal network connectivity in neurofibromatosis 1. Hum Brain Mapp. 2015 Nov; 36(11):4566-81. Tomson SN, Schreiner MJ, Narayan M, Rosser T, Enrique N, Silva AJ, Allen GI, Bookheimer SY, Bearden CE. PMID: 26304096.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    18. The need for novel informatics tools for integrating and planning research in molecular and cellular cognition. Learn Mem. 2015 Sep; 22(9):494-8. Silva AJ, Müller KR. PMID: 26286658.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    19. CREB regulates memory allocation in the insular cortex. Curr Biol. 2014 Dec 01; 24(23):2833-7. Sano Y, Shobe JL, Zhou M, Huang S, Shuman T, Cai DJ, Golshani P, Kamata M, Silva AJ. PMID: 25454591.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    20. Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome. Nat Neurosci. 2014 Dec; 17(12):1736-43. Lee YS, Ehninger D, Zhou M, Oh JY, Kang M, Kwak C, Ryu HH, Butz D, Araki T, Cai Y, Balaji J, Sano Y, Nam CI, Kim HK, Kaang BK, Burger C, Neel BG, Silva AJ. PMID: 25383899.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimals
    21. Maternal inflammation contributes to brain overgrowth and autism-associated behaviors through altered redox signaling in stem and progenitor cells. Stem Cell Reports. 2014 Nov 11; 3(5):725-34. Le Belle JE, Sperry J, Ngo A, Ghochani Y, Laks DR, López-Aranda M, Silva AJ, Kornblum HI. PMID: 25418720.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    22. Temporal and region-specific requirements of aCaMKII in spatial and contextual learning. J Neurosci. 2014 Aug 20; 34(34):11180-7. Achterberg KG, Buitendijk GH, Kool MJ, Goorden SM, Post L, Slump DE, Silva AJ, van Woerden GM, Kushner SA, Elgersma Y. PMID: 25143599.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    23. Encoding and storage of spatial information in the retrosplenial cortex. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8661-6. Czajkowski R, Jayaprakash B, Wiltgen B, Rogerson T, Guzman-Karlsson MC, Barth AL, Trachtenberg JT, Silva AJ. PMID: 24912150.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    24. Synaptic tagging during memory allocation. Nat Rev Neurosci. 2014 Mar; 15(3):157-69. Rogerson T, Cai DJ, Frank A, Sano Y, Shobe J, Lopez-Aranda MF, Silva AJ. PMID: 24496410.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    25. The need for research maps to navigate published work and inform experiment planning. Neuron. 2013 Aug 07; 79(3):411-5. Landreth A, Silva AJ. PMID: 23931992.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    26. mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons. Neuron. 2013 Feb 20; 77(4):647-54. Zhou M, Li W, Huang S, Song J, Kim JY, Tian X, Kang E, Sano Y, Liu C, Balaji J, Wu S, Zhou Y, Zhou Y, Parivash SN, Ehninger D, He L, Song H, Ming GL, Silva AJ. PMID: 23439118.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    27. Associative fear learning enhances sparse network coding in primary sensory cortex. Neuron. 2012 Jul 12; 75(1):121-32. Gdalyahu A, Tring E, Polack PO, Gruver R, Golshani P, Fanselow MS, Silva AJ, Trachtenberg JT. PMID: 22794266.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    28. a-Calcium calmodulin kinase II modulates the temporal structure of hippocampal bursting patterns. PLoS One. 2012; 7(2):e31649. Cho J, Bhatt R, Elgersma Y, Silva AJ. PMID: 22363696.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    29. Obituary: A career that transformed neuroscience. Brain Res Bull. 2011 Nov 25; 86(5-6):285-6. Silva AJ. PMID: 21930192.
      View in: PubMed   Mentions:    Fields:    
    30. Constitutively active H-ras accelerates multiple forms of plasticity in developing visual cortex. Proc Natl Acad Sci U S A. 2010 Nov 02; 107(44):19026-31. Kaneko M, Cheetham CE, Lee YS, Silva AJ, Stryker MP, Fox K. PMID: 20937865.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    31. Increased levels of anxiety-related behaviors in a Tsc2 dominant negative transgenic mouse model of tuberous sclerosis. Behav Genet. 2011 May; 41(3):357-63. Ehninger D, Silva AJ. PMID: 20882401.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    32. The hippocampus plays a selective role in the retrieval of detailed contextual memories. Curr Biol. 2010 Aug 10; 20(15):1336-44. Wiltgen BJ, Zhou M, Cai Y, Balaji J, Karlsson MG, Parivash SN, Li W, Silva AJ. PMID: 20637623.
      View in: PubMed   Mentions: 74     Fields:    Translation:Animals
    33. Neurofibromin regulates corticostriatal inhibitory networks during working memory performance. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):13141-6. Shilyansky C, Karlsgodt KH, Cummings DM, Sidiropoulou K, Hardt M, James AS, Ehninger D, Bearden CE, Poirazi P, Jentsch JD, Cannon TD, Levine MS, Silva AJ. PMID: 20624961.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    34. CaMKII "autonomy" is required for initiating but not for maintaining neuronal long-term information storage. J Neurosci. 2010 Jun 16; 30(24):8214-20. Buard I, Coultrap SJ, Freund RK, Lee YS, Dell'Acqua ML, Silva AJ, Bayer KU. PMID: 20554872.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    35. Muscleblind1, but not Dmpk or Six5, contributes to a complex phenotype of muscular and motivational deficits in mouse models of myotonic dystrophy. PLoS One. 2010 Mar 25; 5(3):e9857. Matynia A, Ng CH, Dansithong W, Chiang A, Silva AJ, Reddy S. PMID: 20360842.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    36. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci. 2010 Apr; 13(4):423-30. Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G. PMID: 20228804.
      View in: PubMed   Mentions: 343     Fields:    Translation:AnimalsCells
    37. Molecular and cellular approaches to memory allocation in neural circuits. Science. 2009 Oct 16; 326(5951):391-5. Silva AJ, Zhou Y, Rogerson T, Shobe J, Balaji J. PMID: 19833959.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    38. CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala. Nat Neurosci. 2009 Nov; 12(11):1438-43. Zhou Y, Won J, Karlsson MG, Zhou M, Rogerson T, Balaji J, Neve R, Poirazi P, Silva AJ. PMID: 19783993.
      View in: PubMed   Mentions: 146     Fields:    Translation:AnimalsCells
    39. Genetics and neuropsychiatric disorders: treatment during adulthood. Nat Med. 2009 Aug; 15(8):849-50. Ehninger D, Silva AJ. PMID: 19661989.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    40. Dissociated fear and spatial learning in mice with deficiency of ataxin-2. PLoS One. 2009 Jul 20; 4(7):e6235. Huynh DP, Maalouf M, Silva AJ, Schweizer FE, Pulst SM. PMID: 19617910.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    41. Adult reversal of cognitive phenotypes in neurodevelopmental disorders. J Neurodev Disord. 2009 Jun; 1(2):150-7. Silva AJ, Ehninger D. PMID: 19812701.
      View in: PubMed   Mentions: 17     Fields:    
    42. DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Hum Mol Genet. 2009 Aug 01; 18(15):2875-88. Hutnick LK, Golshani P, Namihira M, Xue Z, Matynia A, Yang XW, Silva AJ, Schweizer FE, Fan G. PMID: 19433415.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    43. The molecular and cellular biology of enhanced cognition. Nat Rev Neurosci. 2009 Feb; 10(2):126-40. Lee YS, Silva AJ. PMID: 19153576.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    44. Reversing neurodevelopmental disorders in adults. Neuron. 2008 Dec 26; 60(6):950-60. Ehninger D, Li W, Fox K, Stryker MP, Silva AJ. PMID: 19109903.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimals
    45. Neurofibromin regulation of ERK signaling modulates GABA release and learning. Cell. 2008 Oct 31; 135(3):549-60. Cui Y, Costa RM, Murphy GG, Elgersma Y, Zhu Y, Gutmann DH, Parada LF, Mody I, Silva AJ. PMID: 18984165.
      View in: PubMed   Mentions: 170     Fields:    Translation:AnimalsCells
    46. Autophosphorylation of alphaCaMKII is differentially involved in new learning and unlearning mechanisms of memory extinction. Learn Mem. 2008 Nov; 15(11):837-43. Kimura R, Silva AJ, Ohno M. PMID: 18984565.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    47. Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis. Nat Med. 2008 Aug; 14(8):843-8. Ehninger D, Han S, Shilyansky C, Zhou Y, Li W, Kwiatkowski DJ, Ramesh V, Silva AJ. PMID: 18568033.
      View in: PubMed   Mentions: 330     Fields:    Translation:AnimalsCells
    48. A high through-put reverse genetic screen identifies two genes involved in remote memory in mice. PLoS One. 2008 May 07; 3(5):e2121. Matynia A, Anagnostaras SG, Wiltgen BJ, Lacuesta M, Fanselow MS, Silva AJ. PMID: 18464936.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    49. The science of research: the principles underlying the discovery of cognitive and other biological mechanisms. J Physiol Paris. 2007 Jul-Nov; 101(4-6):203-13. Silva AJ. PMID: 18280120.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    50. Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning. J Neurosci. 2007 Dec 12; 27(50):13843-53. Zhou Y, Takahashi E, Li W, Halt A, Wiltgen B, Ehninger D, Li GD, Hell JW, Kennedy MB, Silva AJ. PMID: 18077696.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    51. Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18280-5. Li W, Zhou Y, Jentsch JD, Brown RA, Tian X, Ehninger D, Hennah W, Peltonen L, Lönnqvist J, Huttunen MO, Kaprio J, Trachtenberg JT, Silva AJ, Cannon TD. PMID: 17984054.
      View in: PubMed   Mentions: 94     Fields:    Translation:Animals
    52. Molecular and cellular mechanisms of memory allocation in neuronetworks. Neurobiol Learn Mem. 2008 Mar; 89(3):285-92. Won J, Silva AJ. PMID: 17962049.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    53. Kinase activity is not required for alphaCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses. Nat Neurosci. 2007 Sep; 10(9):1125-7. Hojjati MR, van Woerden GM, Tyler WJ, Giese KP, Silva AJ, Pozzo-Miller L, Elgersma Y. PMID: 17660813.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    54. Neuronal competition and selection during memory formation. Science. 2007 Apr 20; 316(5823):457-60. Han JH, Kushner SA, Yiu AP, Cole CJ, Matynia A, Brown RA, Neve RL, Guzowski JF, Silva AJ, Josselyn SA. PMID: 17446403.
      View in: PubMed   Mentions: 189     Fields:    Translation:AnimalsCells
    55. Memory for context becomes less specific with time. Learn Mem. 2007 Apr; 14(4):313-7. Wiltgen BJ, Silva AJ. PMID: 17522020.
      View in: PubMed   Mentions: 83     Fields:    Translation:Animals
    56. Investigation of age-related cognitive decline using mice as a model system: behavioral correlates. Am J Geriatr Psychiatry. 2006 Dec; 14(12):1004-11. Murphy GG, Rahnama NP, Silva AJ. PMID: 17138807.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    57. Investigation of age-related cognitive decline using mice as a model system: neurophysiological correlates. Am J Geriatr Psychiatry. 2006 Dec; 14(12):1012-21. Murphy GG, Shah V, Hell JW, Silva AJ. PMID: 17138808.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    58. Stability of recent and remote contextual fear memory. Learn Mem. 2006 Jul-Aug; 13(4):451-7. Frankland PW, Ding HK, Takahashi E, Suzuki A, Kida S, Silva AJ. PMID: 16882861.
      View in: PubMed   Mentions: 79     Fields:    Translation:Animals
    59. Differential effects of alphaCaMKII mutation on hippocampal learning and changes in intrinsic neuronal excitability. Eur J Neurosci. 2006 Apr; 23(8):2235-40. Ohno M, Sametsky EA, Silva AJ, Disterhoft JF. PMID: 16630070.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    60. Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory. J Neurosci. 2006 Feb 15; 26(7):1923-34. Nagy V, Bozdagi O, Matynia A, Balcerzyk M, Okulski P, Dzwonek J, Costa RM, Silva AJ, Kaczmarek L, Huntley GW. PMID: 16481424.
      View in: PubMed   Mentions: 154     Fields:    Translation:AnimalsCells
    61. Forebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memory. J Neurosci Res. 2006 Jan; 83(1):28-38. Chen AP, Ohno M, Giese KP, Kühn R, Chen RL, Silva AJ. PMID: 16342120.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    62. The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1. Curr Biol. 2005 Nov 08; 15(21):1961-7. Li W, Cui Y, Kushner SA, Brown RA, Jentsch JD, Frankland PW, Cannon TD, Silva AJ. PMID: 16271875.
      View in: PubMed   Mentions: 139     Fields:    Translation:Animals
    63. Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway. J Neurosci. 2005 Oct 19; 25(42):9721-34. Kushner SA, Elgersma Y, Murphy GG, Jaarsma D, van Woerden GM, Hojjati MR, Cui Y, LeBoutillier JC, Marrone DF, Choi ES, De Zeeuw CI, Petit TL, Pozzo-Miller L, Silva AJ. PMID: 16237176.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    64. Notch to remember. Trends Neurosci. 2005 Aug; 28(8):429-35. Costa RM, Drew C, Silva AJ. PMID: 15922461.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    65. Trace eyeblink conditioning requires the hippocampus but not autophosphorylation of alphaCaMKII in mice. Learn Mem. 2005 May-Jun; 12(3):211-5. Ohno M, Tseng W, Silva AJ, Disterhoft JF. PMID: 15897256.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    66. Increased neuronal excitability, synaptic plasticity, and learning in aged Kvbeta1.1 knockout mice. Curr Biol. 2004 Nov 09; 14(21):1907-15. Murphy GG, Fedorov NB, Giese KP, Ohno M, Friedman E, Chen R, Silva AJ. PMID: 15530391.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    67. New circuits for old memories: the role of the neocortex in consolidation. Neuron. 2004 Sep 30; 44(1):101-8. Wiltgen BJ, Brown RA, Talton LE, Silva AJ. PMID: 15450163.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimals
    68. Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Curr Biol. 2004 Sep 21; 14(18):1657-63. Israely I, Costa RM, Xie CW, Silva AJ, Kosik KS, Liu X. PMID: 15380068.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    69. Memory reconsolidation and extinction have distinct temporal and biochemical signatures. J Neurosci. 2004 May 19; 24(20):4787-95. Suzuki A, Josselyn SA, Frankland PW, Masushige S, Silva AJ, Kida S. PMID: 15152039.
      View in: PubMed   Mentions: 333     Fields:    Translation:Animals
    70. The involvement of the anterior cingulate cortex in remote contextual fear memory. Science. 2004 May 07; 304(5672):881-3. Frankland PW, Bontempi B, Talton LE, Kaczmarek L, Silva AJ. PMID: 15131309.
      View in: PubMed   Mentions: 262     Fields:    Translation:AnimalsCells
    71. Molecular and cellular cognition; the unraveling of memory retrieval. Cell. 2004 Apr 02; 117(1):3-4. Brown R, Silva AJ. PMID: 15066276.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    72. Consolidation of CS and US representations in associative fear conditioning. Hippocampus. 2004; 14(5):557-69. Frankland PW, Josselyn SA, Anagnostaras SG, Kogan JH, Takahashi E, Silva AJ. PMID: 15301434.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    73. The antimetabolite ara-CTP blocks long-term memory of conditioned taste aversion. Learn Mem. 2003 Nov-Dec; 10(6):503-9. Wang J, Ren K, Pérez J, Silva AJ, Peña de Ortiz S. PMID: 14657261.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    74. Learning and memory deficits in Notch mutant mice. Curr Biol. 2003 Aug 05; 13(15):1348-54. Costa RM, Honjo T, Silva AJ. PMID: 12906797.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    75. Pharmacologically regulated induction of silent mutations (PRISM): combined pharmacological and genetic approaches for learning and memory. Neuroscientist. 2003 Apr; 9(2):104-9. Frankland PW, Ohno M, Takahashi E, Chen AR, Costa RM, Kushner SA, Silva AJ. PMID: 12708614.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    76. The RAS effector RIN1 modulates the formation of aversive memories. J Neurosci. 2003 Feb 01; 23(3):748-57. Dhaka A, Costa RM, Hu H, Irvin DK, Patel A, Kornblum HI, Silva AJ, O'Dell TJ, Colicelli J. PMID: 12574403.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    77. Molecular and cellular cognitive studies of the role of synaptic plasticity in memory. J Neurobiol. 2003 Jan; 54(1):224-37. Silva AJ. PMID: 12486706.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    78. Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice. Nat Neurosci. 2003 Jan; 6(1):51-8. Anagnostaras SG, Murphy GG, Hamilton SE, Mitchell SL, Rahnama NP, Nathanson NM, Silva AJ. PMID: 12483218.
      View in: PubMed   Mentions: 139     Fields:    Translation:Animals
    79. Mouse models of neurofibromatosis type I: bridging the GAP. Trends Mol Med. 2003 Jan; 9(1):19-23. Costa RM, Silva AJ. PMID: 12524206.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    80. Autophosphorylation of alphaCaMKII is required for ocular dominance plasticity. Neuron. 2002 Oct 24; 36(3):483-91. Taha S, Hanover JL, Silva AJ, Stryker MP. PMID: 12408850.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    81. Inhibitory autophosphorylation of CaMKII controls PSD association, plasticity, and learning. Neuron. 2002 Oct 24; 36(3):493-505. Elgersma Y, Fedorov NB, Ikonen S, Choi ES, Elgersma M, Carvalho OM, Giese KP, Silva AJ. PMID: 12408851.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
    82. Genetic approaches to molecular and cellular cognition: a focus on LTP and learning and memory. Annu Rev Genet. 2002; 36:687-720. Matynia A, Kushner SA, Silva AJ. PMID: 12429705.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    83. The molecules of forgetfulness. Nature. 2002 Aug 29; 418(6901):929-30. Silva AJ, Josselyn SA. PMID: 12198533.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    84. Molecular and cellular mechanisms underlying the cognitive deficits associated with neurofibromatosis 1. J Child Neurol. 2002 Aug; 17(8):622-6; discussion 627-9, 646-51. Costa RM, Silva AJ. PMID: 12403561.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    85. A pharmacogenetic inducible approach to the study of NMDA/alphaCaMKII signaling in synaptic plasticity. Curr Biol. 2002 Apr 16; 12(8):654-6. Ohno M, Frankland PW, Silva AJ. PMID: 11967152.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    86. CREB required for the stability of new and reactivated fear memories. Nat Neurosci. 2002 Apr; 5(4):348-55. Kida S, Josselyn SA, Peña de Ortiz S, Kogan JH, Chevere I, Masushige S, Silva AJ. PMID: 11889468.
      View in: PubMed   Mentions: 193     Fields:    Translation:Animals
    87. Central nervous system myelination in mice with deficient expression of Notch1 receptor. J Neurosci Res. 2002 Feb 01; 67(3):309-20. Givogri MI, Costa RM, Schonmann V, Silva AJ, Campagnoni AT, Bongarzone ER. PMID: 11813235.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    88. Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1. Nature. 2002 Jan 31; 415(6871):526-30. Costa RM, Federov NB, Kogan JH, Murphy GG, Stern J, Ohno M, Kucherlapati R, Jacks T, Silva AJ. PMID: 11793011.
      View in: PubMed   Mentions: 185     Fields:    Translation:Animals
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