Sanaz Memarzadeh

Title(s)Professor, Obstetrics and Gynecology
SchoolMedicine
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    Reactivating p53 Function with a Novel Structure-based Peptide as a Therapeutic Approach for Overcoming Platinum Resistance
    NIH I01BX004651Jan 1, 2020 - Dec 31, 2023
    Role: Principal Investigator
    Pathobiology and Mechanism of Progesterone Resistance in Human Endometrial Cancer
    NIH R01CA183877Mar 1, 2015 - Feb 28, 2021
    Role: Principal Investigator
    Role of estrogen receptor in endometrial cancer initiation and progression
    NIH IK2BX001305Jul 1, 2011 - Jun 30, 2016
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Safety and efficacy of mirvetuximab soravtansine, a folate receptor alpha (FRa)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer. Gynecol Oncol. 2023 03; 170:241-247. Gilbert L, Oaknin A, Matulonis UA, Mantia-Smaldone GM, Lim PC, Castro CM, Provencher D, Memarzadeh S, Method M, Wang J, Moore KN, O'Malley DM. PMID: 36736157.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. Expression of immune checkpoint regulators, programmed death-ligand 1 (PD-L1/PD-1), cytotoxic T lymphocyte antigen 4 (CTLA-4), and indolaimine-2, 3-deoxygenase (IDO) in uterine mesenchymal tumors. Diagn Pathol. 2022 Sep 14; 17(1):70. Samiei A, Gjertson DW, Memarzadeh S, Konecny GE, Moatamed NA. PMID: 36104728; PMCID: PMC9476344.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Inability of ovarian cancers to upregulate their MHC-class I surface expression marks their aggressiveness and increased susceptibility to NK cell-mediated cytotoxicity. Cancer Immunol Immunother. 2022 Dec; 71(12):2929-2941. Chovatiya N, Kaur K, Huerta-Yepez S, Chen PC, Neal A, DiBernardo G, Gumrukcu S, Memarzadeh S, Jewett A. PMID: 35507102.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. cfTrack: A Method of Exome-Wide Mutation Analysis of Cell-free DNA to Simultaneously Monitor the Full Spectrum of Cancer Treatment Outcomes Including MRD, Recurrence, and Evolution. Clin Cancer Res. 2022 05 02; 28(9):1841-1853. Li S, Zeng W, Ni X, Zhou Y, Stackpole ML, Noor ZS, Yuan Z, Neal A, Memarzadeh S, Garon EB, Dubinett SM, Li W, Zhou XJ. PMID: 35149536; PMCID: PMC9126584.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Efficacy of birinapant in combination with carboplatin in targeting platinum‑resistant epithelial ovarian cancers. Int J Oncol. 2022 Mar; 60(3). Singh T, Neal A, Dibernardo G, Raheseparian N, Moatamed NA, Memarzadeh S. PMID: 35191515; PMCID: PMC8878637.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Combining ReACp53 with Carboplatin to Target High-Grade Serous Ovarian Cancers. Cancers (Basel). 2021 Nov 24; 13(23). Neal A, Lai T, Singh T, Rahseparian N, Grogan T, Elashoff D, Scott P, Pellegrini M, Memarzadeh S. PMID: 34885017; PMCID: PMC8657291.
      View in: PubMed   Mentions: 6  
    7. Management of Clitoral Melanoma Presenting as an Exophytic Clitoral Mass: A Case Report and Review of the Literature. Curr Oncol. 2021 10 21; 28(6):4264-4272. Szlachta-McGinn A, Chmielowski B, Kang Y, Raman S, Memarzadeh S. PMID: 34898540; PMCID: PMC8544559.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Gynecologic tumor board: a radiologist's guide to vulvar and vaginal malignancies. Abdom Radiol (NY). 2021 12; 46(12):5669-5686. Chow L, Tsui BQ, Bahrami S, Masamed R, Memarzadeh S, Raman SS, Patel MK. PMID: 34435227; PMCID: PMC8590682.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. A rare case of vulvar extraskeletal myxoid chondrosarcoma: mimics and diagnostic clues. Autops Case Rep. 2021; 11:e2021322. Liou SS, Memarzadeh S, Dry SM, Graham RP, Moatamed NA. PMID: 34458187; PMCID: PMC8387072.
      View in: PubMed   Mentions:
    10. Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy. Nat Commun. 2021 06 10; 12(1):3530. Wang YC, Wang X, Yu J, Ma F, Li Z, Zhou Y, Zeng S, Ma X, Li YR, Neal A, Huang J, To A, Clarke N, Memarzadeh S, Pellegrini M, Yang L. PMID: 34112755; PMCID: PMC8192781.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    11. Image-Guided Percutaneous Thermal Ablation of Oligometastatic Ovarian and Non-Ovarian Gynecologic Tumors. J Vasc Interv Radiol. 2021 05; 32(5):729-738. Yuan F, Wei SH, Konecny GE, Memarzadeh S, Suh RD, Sayre J, Lu DS, Raman SS. PMID: 33608192.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Matched sequential tumor molecular profiling in solid malignancies may impact clinical practice. Cancer Genet. 2021 04; 252-253:73-79. Lai TS, Manrriquez E, Neal A, Memarzadeh S. PMID: 33434795.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Exploring the Potential of Drug Response Assays for Precision Medicine in Ovarian Cancer. Int J Mol Sci. 2020 Dec 30; 22(1). Singh T, Neal AS, Moatamed NA, Memarzadeh S. PMID: 33396714; PMCID: PMC7794771.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    14. The uterine pathological features associated with sentinel lymph node metastasis in endometrial carcinomas. PLoS One. 2020; 15(11):e0242772. Kang Y, Kim TH, Gjertson DW, Cohen JG, Memarzadeh S, Moatamed NA. PMID: 33232380; PMCID: PMC7685478.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. 68Ga-FAPi-46 diffuse bilateral breast uptake in a patient with cervical cancer after hormonal stimulation. Eur J Nucl Med Mol Imaging. 2021 03; 48(3):924-926. Sonni I, Lee-Felker S, Memarzadeh S, Quinn MM, Mona CE, Lückerath K, Czernin J, Calais J. PMID: 32651662.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    16. An asymptomatic anterior vaginal wall endometrioma, a rare manifestation of endometriosis: A case report. Case Rep Womens Health. 2020 Jul; 27:e00210. Dilday EA, Lewis MS, Vahidi K, Memarzadeh S. PMID: 32551235; PMCID: PMC7287488.
      View in: PubMed   Mentions: 1  
    17. Expression of Stromal Progesterone Receptor and Differential Methylation Patterns in the Endometrium May Correlate with Response to Progesterone Therapy in Endometrial Complex Atypical Hyperplasia. Reprod Sci. 2020 09; 27(9):1778-1790. Neal AS, Nunez M, Lai T, Tosevska A, Morselli M, Amneus M, Zakhour M, Moatamed NA, Pellegrini M, Memarzadeh S. PMID: 32124398; PMCID: PMC7395059.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    18. A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids. Commun Biol. 2019; 2:78. Phan N, Hong JJ, Tofig B, Mapua M, Elashoff D, Moatamed NA, Huang J, Memarzadeh S, Damoiseaux R, Soragni A. PMID: 30820473; PMCID: PMC6389967.
      View in: PubMed   Mentions: 82  Translation:Humans
    19. Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy. Stem Cells Dev. 2016 12 15; 25(24):1863-1873. Smith DJ, Lin LJ, Moon H, Pham AT, Wang X, Liu S, Ji S, Rezek V, Shimizu S, Ruiz M, Lam J, Janzen DM, Memarzadeh S, Kohn DB, Zack JA, Kitchen SG, An DS, Yang L. PMID: 27608727; PMCID: PMC5165681.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    20. A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas. Cancer Cell. 2016 Jan 11; 29(1):90-103. Soragni A, Janzen DM, Johnson LM, Lindgren AG, Thai-Quynh Nguyen A, Tiourin E, Soriaga AB, Lu J, Jiang L, Faull KF, Pellegrini M, Memarzadeh S, Eisenberg DS. PMID: 26748848; PMCID: PMC4733364.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    21. Tubal Ligation Induces Quiescence in the Epithelia of the Fallopian Tube Fimbria. Reprod Sci. 2015 Oct; 22(10):1262-71. Tiourin E, Velasco VS, Rosales MA, Sullivan PS, Janzen DM, Memarzadeh S. PMID: 25736327; PMCID: PMC5933088.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    22. Low levels of circulating estrogen sensitize PTEN-null endometrial tumors to PARP inhibition in vivo. Mol Cancer Ther. 2013 Dec; 12(12):2917-28. Janzen DM, Paik DY, Rosales MA, Yep B, Cheng D, Witte ON, Kayadibi H, Ryan CM, Jung ME, Faull K, Memarzadeh S. PMID: 24222661; PMCID: PMC3904550.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    23. Progesterone receptor signaling in the microenvironment of endometrial cancer influences its response to hormonal therapy. Cancer Res. 2013 Aug 01; 73(15):4697-710. Janzen DM, Rosales MA, Paik DY, Lee DS, Smith DA, Witte ON, Iruela-Arispe ML, Memarzadeh S. PMID: 23744837; PMCID: PMC3752407.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    24. Estrogen and progesterone together expand murine endometrial epithelial progenitor cells. Stem Cells. 2013 Apr; 31(4):808-22. Janzen DM, Cheng D, Schafenacker AM, Paik DY, Goldstein AS, Witte ON, Jaroszewicz A, Pellegrini M, Memarzadeh S. PMID: 23341289; PMCID: PMC3774116.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    25. Stem-like epithelial cells are concentrated in the distal end of the fallopian tube: a site for injury and serous cancer initiation. Stem Cells. 2012 Nov; 30(11):2487-97. Paik DY, Janzen DM, Schafenacker AM, Velasco VS, Shung MS, Cheng D, Huang J, Witte ON, Memarzadeh S. PMID: 22911892; PMCID: PMC4442093.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    26. Collaboration of Kras and androgen receptor signaling stimulates EZH2 expression and tumor-propagating cells in prostate cancer. Cancer Res. 2012 Sep 15; 72(18):4672-81. Cai H, Memarzadeh S, Stoyanova T, Beharry Z, Kraft AS, Witte ON. PMID: 22805308; PMCID: PMC3445707.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    27. Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7962-7. Memarzadeh S, Cai H, Janzen DM, Xin L, Lukacs R, Riedinger M, Zong Y, DeGendt K, Verhoeven G, Huang J, Witte ON. PMID: 21518863; PMCID: PMC3093518.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    28. Differential transformation capacity of Src family kinases during the initiation of prostate cancer. Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16):6579-84. Cai H, Smith DA, Memarzadeh S, Lowell CA, Cooper JA, Witte ON. PMID: 21464326; PMCID: PMC3080985.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    29. Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation. Cell Stem Cell. 2010 Dec 03; 7(6):682-93. Lukacs RU, Memarzadeh S, Wu H, Witte ON. PMID: 21112563; PMCID: PMC3019762.
      View in: PubMed   Mentions: 153     Fields:    Translation:AnimalsCells
    30. Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium. Proc Natl Acad Sci U S A. 2010 Oct 05; 107(40):17298-303. Memarzadeh S, Zong Y, Janzen DM, Goldstein AS, Cheng D, Kurita T, Schafenacker AM, Huang J, Witte ON. PMID: 20855612; PMCID: PMC2951427.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    31. Basal epithelial stem cells are efficient targets for prostate cancer initiation. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2610-5. Lawson DA, Zong Y, Memarzadeh S, Xin L, Huang J, Witte ON. PMID: 20133806; PMCID: PMC2823887.
      View in: PubMed   Mentions: 148     Fields:    Translation:HumansAnimalsCells
    32. Non-Peutz-Jeghers syndrome associated ovarian sex cord tumor with annular tubules: a case report. Fertil Steril. 2009 Oct; 92(4):1497.e5-1497.e8. Nosov V, Park S, Rao J, Memarzadeh S. PMID: 19703688.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    33. Enhanced paracrine FGF10 expression promotes formation of multifocal prostate adenocarcinoma and an increase in epithelial androgen receptor. Cancer Cell. 2007 Dec; 12(6):572-85. Memarzadeh S, Xin L, Mulholland DJ, Mansukhani A, Wu H, Teitell MA, Witte ON. PMID: 18068633; PMCID: PMC2931420.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    34. Lymphovascular and perineural invasion in the parametria: a prognostic factor for early-stage cervical cancer. Obstet Gynecol. 2003 Sep; 102(3):612-9. Memarzadeh S, Natarajan S, Dandade DP, Ostrzega N, Saber PA, Busuttil A, Lentz SE, Berek JS. PMID: 12962952.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    35. Urokinase plasminogen activator receptor: Prognostic biomarker for endometrial cancer. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10647-52. Memarzadeh S, Kozak KR, Chang L, Natarajan S, Shintaku P, Reddy ST, Farias-Eisner R, Memarzedeh S. PMID: 12130664; PMCID: PMC125001.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
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