Frank U Alber

Title(s)Professor, MIMG
SchoolMedicine
Address609 Charles E. Young Drive, Ea 1602A
Los Angeles CA 90024
Phone310-267-0363
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sensitive detection of tumor mutations from blood and its application to immunotherapy prognosis. Nat Commun. 2021 07 07; 12(1):4172. Li S, Noor ZS, Zeng W, Stackpole ML, Ni X, Zhou Y, Yuan Z, Wong WH, Agopian VG, Dubinett SM, Alber F, Li W, Garon EB, Zhou XJ. PMID: 34234141.
      View in: PubMed   Mentions:    Fields:    
    2. Assessment of scoring functions to rank the quality of 3D subtomogram clusters from cryo-electron tomography. J Struct Biol. 2021 Jun; 213(2):107727. Singla J, White KL, Stevens RC, Alber F. PMID: 33753204.
      View in: PubMed   Mentions:    Fields:    
    3. Visualizing subcellular rearrangements in intact ß cells using soft x-ray tomography. Sci Adv. 2020 Dec; 6(50). White KL, Singla J, Loconte V, Chen JH, Ekman A, Sun L, Zhang X, Francis JP, Li A, Lin W, Tseng K, McDermott G, Alber F, Sali A, Larabell C, Stevens RC. PMID: 33298443.
      View in: PubMed   Mentions:    Fields:    
    4. Spatial Principles of Chromatin Architecture Associated With Organ-Specific Gene Regulation. Front Cardiovasc Med. 2018; 5:186. Chapski DJ, Rosa-Garrido M, Hua N, Alber F, Vondriska TM. PMID: 30697540.
      View in: PubMed   Mentions:
    5. CancerDetector: ultrasensitive and non-invasive cancer detection at the resolution of individual reads using cell-free DNA methylation sequencing data. Nucleic Acids Res. 2018 09 06; 46(15):e89. Li W, Li Q, Kang S, Same M, Zhou Y, Sun C, Liu CC, Matsuoka L, Sher L, Wong WH, Alber F, Zhou XJ. PMID: 29897492.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    6. Producing genome structure populations with the dynamic and automated PGS software. Nat Protoc. 2018 05; 13(5):915-926. Hua N, Tjong H, Shin H, Gong K, Zhou XJ, Alber F. PMID: 29622804.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    7. Opportunities and Challenges in Building a Spatiotemporal Multi-scale Model of the Human Pancreatic ß Cell. Cell. 2018 03 22; 173(1):11-19. Singla J, McClary KM, White KL, Alber F, Sali A, Stevens RC. PMID: 29570991.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    8. Quantitative Methods to Investigate the 4D Dynamics of Heterochromatic Repair Sites in Drosophila Cells. Methods Enzymol. 2018; 601:359-389. Caridi CP, Delabaere L, Tjong H, Hopp H, Das D, Alber F, Chiolo I. PMID: 29523239.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    9. The three-dimensional genome organization of Drosophila melanogaster through data integration. Genome Biol. 2017 07 31; 18(1):145. Li Q, Tjong H, Li X, Gong K, Zhou XJ, Chiolo I, Alber F. PMID: 28760140.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    10. TomoMiner and TomoMinerCloud: A Software Platform for Large-Scale Subtomogram Structural Analysis. Structure. 2017 06 06; 25(6):951-961.e2. Frazier Z, Xu M, Alber F. PMID: 28552576.
      View in: PubMed   Mentions: 5     Fields:    
    11. CancerLocator: non-invasive cancer diagnosis and tissue-of-origin prediction using methylation profiles of cell-free DNA. Genome Biol. 2017 03 24; 18(1):53. Kang S, Li Q, Chen Q, Zhou Y, Park S, Lee G, Grimes B, Krysan K, Yu M, Wang W, Alber F, Sun F, Dubinett SM, Li W, Zhou XJ. PMID: 28335812.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    12. Comprehensive characterization of neutrophil genome topology. Genes Dev. 2017 01 15; 31(2):141-153. Zhu Y, Gong K, Denholtz M, Chandra V, Kamps MP, Alber F, Murre C. PMID: 28167501.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    13. Simulating cryo electron tomograms of crowded cell cytoplasm for assessment of automated particle picking. BMC Bioinformatics. 2016 Oct 05; 17(1):405. Pei L, Xu M, Frazier Z, Alber F. PMID: 27716029.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    14. Mining 3D genome structure populations identifies major factors governing the stability of regulatory communities. Nat Commun. 2016 05 31; 7:11549. Dai C, Li W, Tjong H, Hao S, Zhou Y, Li Q, Chen L, Zhu B, Alber F, Jasmine Zhou X. PMID: 27240697.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    15. Population-based 3D genome structure analysis reveals driving forces in spatial genome organization. Proc Natl Acad Sci U S A. 2016 Mar 22; 113(12):E1663-72. Tjong H, Li W, Kalhor R, Dai C, Hao S, Gong K, Zhou Y, Li H, Zhou XJ, Le Gros MA, Larabell CA, Chen L, Alber F. PMID: 26951677.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    16. TopDom: an efficient and deterministic method for identifying topological domains in genomes. Nucleic Acids Res. 2016 Apr 20; 44(7):e70. Shin H, Shi Y, Dai C, Tjong H, Gong K, Alber F, Zhou XJ. PMID: 26704975.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    17. Comparative 3D genome structure analysis of the fission and the budding yeast. PLoS One. 2015; 10(3):e0119672. Gong K, Tjong H, Zhou XJ, Alber F. PMID: 25799503.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    18. Hi-Corrector: a fast, scalable and memory-efficient package for normalizing large-scale Hi-C data. Bioinformatics. 2015 Mar 15; 31(6):960-2. Li W, Gong K, Li Q, Alber F, Zhou XJ. PMID: 25391400.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    19. Automated target segmentation and real space fast alignment methods for high-throughput classification and averaging of crowded cryo-electron subtomograms. Bioinformatics. 2013 Jul 01; 29(13):i274-82. Xu M, Alber F. PMID: 23812994.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    20. High precision alignment of cryo-electron subtomograms through gradient-based parallel optimization. BMC Syst Biol. 2012; 6 Suppl 1:S18. Xu M, Alber F. PMID: 23046491.
      View in: PubMed   Mentions: 9     Fields:    
    21. A computational approach to increase time scales in Brownian dynamics-based reaction-diffusion modeling. J Comput Biol. 2012 Jun; 19(6):606-18. Frazier Z, Alber F. PMID: 22697237.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    22. Physical tethering and volume exclusion determine higher-order genome organization in budding yeast. Genome Res. 2012 Jul; 22(7):1295-305. Tjong H, Gong K, Chen L, Alber F. PMID: 22619363.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    23. High-throughput subtomogram alignment and classification by Fourier space constrained fast volumetric matching. J Struct Biol. 2012 May; 178(2):152-64. Xu M, Beck M, Alber F. PMID: 22420977.
      View in: PubMed   Mentions: 21     Fields:    
    24. Genome architectures revealed by tethered chromosome conformation capture and population-based modeling. Nat Biotechnol. 2011 Dec 25; 30(1):90-8. Kalhor R, Tjong H, Jayathilaka N, Alber F, Chen L. PMID: 22198700.
      View in: PubMed   Mentions: 266     Fields:    Translation:HumansCells
    25. Template-free detection of macromolecular complexes in cryo electron tomograms. Bioinformatics. 2011 Jul 01; 27(13):i69-76. Xu M, Beck M, Alber F. PMID: 21685103.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    26. Gradient-based high precision alignment of cryo-electron subtomograms. IEEE Int Conf Systems Biol. 2011; 279-284. Xu M, Alber F. PMID: 25068871.
      View in: PubMed   Mentions:
    27. A fast mathematical programming procedure for simultaneous fitting of assembly components into cryoEM density maps. Bioinformatics. 2010 Jun 15; 26(12):i261-8. Zhang S, Vasishtan D, Xu M, Topf M, Alber F. PMID: 20529915.
      View in: PubMed   Mentions: 10     Fields:    
    28. Integrating diverse data for structure determination of macromolecular assemblies. Annu Rev Biochem. 2008; 77:443-77. Alber F, Förster F, Korkin D, Topf M, Sali A. PMID: 18318657.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    29. Determining the architectures of macromolecular assemblies. Nature. 2007 Nov 29; 450(7170):683-94. Alber F, Dokudovskaya S, Veenhoff LM, Zhang W, Kipper J, Devos D, Suprapto A, Karni-Schmidt O, Williams R, Chait BT, Rout MP, Sali A. PMID: 18046405.
      View in: PubMed   Mentions: 239     Fields:    Translation:AnimalsCells
    30. The molecular architecture of the nuclear pore complex. Nature. 2007 Nov 29; 450(7170):695-701. Alber F, Dokudovskaya S, Veenhoff LM, Zhang W, Kipper J, Devos D, Suprapto A, Karni-Schmidt O, Williams R, Chait BT, Sali A, Rout MP. PMID: 18046406.
      View in: PubMed   Mentions: 431     Fields:    Translation:AnimalsCells
    31. Structural modeling of protein interactions by analogy: application to PSD-95. PLoS Comput Biol. 2006 Nov 10; 2(11):e153. Korkin D, Davis FP, Alber F, Luong T, Shen MY, Lucic V, Kennedy MB, Sali A. PMID: 17096593.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    32. Simple fold composition and modular architecture of the nuclear pore complex. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2172-7. Devos D, Dokudovskaya S, Williams R, Alber F, Eswar N, Chait BT, Rout MP, Sali A. PMID: 16461911.
      View in: PubMed   Mentions: 128     Fields:    Translation:AnimalsCells
    33. Structural characterization of assemblies from overall shape and subcomplex compositions. Structure. 2005 Mar; 13(3):435-45. Alber F, Kim MF, Sali A. PMID: 15766545.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    34. Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry. Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47):16454-9. Chu F, Shan SO, Moustakas DT, Alber F, Egea PF, Stroud RM, Walter P, Burlingame AL. PMID: 15546976.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    35. Components of coated vesicles and nuclear pore complexes share a common molecular architecture. PLoS Biol. 2004 Dec; 2(12):e380. Devos D, Dokudovskaya S, Alber F, Williams R, Chait BT, Sali A, Rout MP. PMID: 15523559.
      View in: PubMed   Mentions: 170     Fields:    Translation:AnimalsCells
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