Patrick J Frost

Title(s)Associate Adjunct Professor, Medicine
SchoolMedicine
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    Collapse Research 
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    ShEEP Request for Small Animal Magnetic Resonance Imaging System
    NIH IS1BX005024Sep 1, 2019 - Aug 31, 2020
    Role: Principal Investigator
    Targeting the in Vivo Hypoxic Microenvironment of Multiple Myeloma as an Anti-Tumor Strategy
    NIH I01BX004280Jul 1, 2019 - Jun 30, 2023
    Role: Principal Investigator
    Acquisition of a SOPHIA G8 PET/CT Animal Imager
    NIH IS1BX003089Apr 1, 2015 - Sep 30, 2015
    Role: Principal Investigator
    Effects of mTOR inhibitors on MM tumors
    NIH I01BX001532Oct 1, 2011 - Sep 30, 2015
    Role: Principal Investigator
    Effects of mTOR inhibitors on multiple myeloma tumors
    NIH K01CA111623Aug 1, 2005 - Jul 31, 2012
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism. Mol Cancer Res. 2016 Apr; 14(4):397-407. Hoang B, Shi Y, Frost PJ, Mysore V, Bardeleben C, Lichtenstein A. PMID: 26869290.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    2. A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity. Mol Cancer Res. 2016 Mar; 14(3):253-66. Mysore VS, Szablowski J, Dervan PB, Frost PJ. PMID: 26801054.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    3. Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin. . 2009 Jan; 8(1):83-93. Frost P, Shi Y, Hoang B, Gera J, Lichtenstein A. PMID: 19139116.
      View in: PubMed   Mentions:
    4. IL-6-induced stimulation of c-myc translation in multiple myeloma cells is mediated by myc internal ribosome entry site function and the RNA-binding protein, hnRNP A1. Cancer Res. 2008 Dec 15; 68(24):10215-22. Shi Y, Frost PJ, Hoang BQ, Benavides A, Sharma S, Gera JF, Lichtenstein AK. PMID: 19074889.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    5. AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells. Oncogene. 2007 Apr 05; 26(16):2255-62. Frost P, Shi Y, Hoang B, Lichtenstein A. PMID: 17016437.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
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