-
A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Sci Transl Med. 2022 09 14; 14(662):eabj2381.
Blaskovich MAT, Hansford KA, Butler MS, Ramu S, Kavanagh AM, Jarrad AM, Prasetyoputri A, Pitt ME, Huang JX, Lindahl F, Ziora ZM, Bradford T, Muldoon C, Rajaratnam P, Pelingon R, Edwards DJ, Zhang B, Amado M, Elliott AG, Zuegg J, Coin L, Woischnig AK, Khanna N, Breidenstein E, Stincone A, Mason C, Khan N, Cho HK, Karau MJ, Greenwood-Quaintance KE, Patel R, Wootton M, James ML, Hutton ML, Lyras D, Ogunniyi AD, Mahdi LK, Trott DJ, Wu X, Niles S, Lewis K, Smith JR, Barber KE, Yim J, Rice SA, Rybak MJ, Ishmael CR, Hori KR, Bernthal NM, Francis KP, Roberts JA, Paterson DL, Cooper MA. PMID: 36103517.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022 04 19; 39(3):110714.
Kenney DJ, O'Connell AK, Turcinovic J, Montanaro P, Hekman RM, Tamura T, Berneshawi AR, Cafiero TR, Al Abdullatif S, Blum B, Goldstein SI, Heller BL, Gertje HP, Bullitt E, Trachtenberg AJ, Chavez E, Nono ET, Morrison C, Tseng AE, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber BR, Saeed M, Balazs AB, Francis KP, Klose A, Paragas N, Campbell JD, Connor JH, Emili A, Crossland NA, Ploss A, Douam F. PMID: 35421379; PMCID: PMC8977517.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
-
In vitro and in vivo methods to study bacterial colonization of hydrogel dermal fillers. J Biomed Mater Res B Appl Biomater. 2022 08; 110(8):1932-1941.
Wang Y, Borthwell RM, Hori K, Clarkson S, Blumstein G, Park H, Hart CM, Hamad CD, Francis KP, Bernthal NM, Phillips KS. PMID: 35352867; PMCID: PMC10371418.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 03 05; 14(3).
Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. PMID: 35336942; PMCID: PMC8955233.
View in:
PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
-
Red blood cell transfusion-induced non-transferrin-bound iron promotes Pseudomonas aeruginosa biofilms in human sera and mortality in catheterized mice. Br J Haematol. 2022 02; 196(4):1105-1110.
La Carpia F, Slate A, Bandyopadhyay S, Wojczyk BS, Godbey EA, Francis KP, Prestia K, Hod EA. PMID: 34726258; PMCID: PMC8831455.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Fatal neuroinvasion and SARS-CoV-2 tropism in K18-hACE2 mice is partially independent on hACE2 expression. bioRxiv. 2021 Sep 23.
Carossino M, Montanaro P, O'Connell A, Kenney D, Gertje H, Grosz K, Ericsson M, Huber BR, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Kurnick S, Bosmann M, Saeed M, Balasuriya U, Douam F, Crossland N. PMID: 33469581; PMCID: PMC7814818.
View in:
PubMed Mentions:
-
Portable bioluminescent platform for in vivo monitoring of biological processes in non-transgenic animals. Nat Commun. 2021 05 11; 12(1):2680.
Yevtodiyenko A, Bazhin A, Khodakivskyi P, Godinat A, Budin G, Maric T, Pietramaggiori G, Scherer SS, Kunchulia M, Eppeldauer G, Polyakov SV, Francis KP, Bryan JN, Goun EA. PMID: 33976191; PMCID: PMC8113525.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Comparison of two fluorescent probes in preclinical non-invasive imaging and image-guided debridement surgery of Staphylococcal biofilm implant infections. Sci Rep. 2021 01 15; 11(1):1622.
Park HY, Zoller SD, Hegde V, Sheppard W, Burke Z, Blumstein G, Hamad C, Sprague M, Hoang J, Smith R, Romero Pastrana F, Czupryna J, Miller LS, López-Álvarez M, Bispo M, van Oosten M, van Dijl JM, Francis KP, Bernthal NM. PMID: 33452271; PMCID: PMC7810895.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Fighting Staphylococcus aureus infections with light and photoimmunoconjugates. JCI Insight. 2020 11 19; 5(22).
Bispo M, Anaya-Sanchez A, Suhani S, Raineri EJM, López-Álvarez M, Heuker M, Szymanski W, Romero Pastrana F, Buist G, Horswill AR, Francis KP, van Dam GM, van Oosten M, van Dijl JM. PMID: 33048846; PMCID: PMC7710284.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
In vivo Mouse Model of Spinal Implant Infection. J Vis Exp. 2020 06 23; (160).
Kelley BV, Hamad C, Zoller SD, Greig D, Mamouei Z, Chun R, Hori K, Cevallos N, Ishmael C, Hsiue P, Trikha R, Sekimura T, Gettleman B, Golzar A, Lin A, Olson T, Chaudry A, Le MM, Scaduto AA, Francis KP, Bernthal NM. PMID: 32658180; PMCID: PMC8601786.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Novel in vivo mouse model of shoulder implant infection. J Shoulder Elbow Surg. 2020 Jul; 29(7):1412-1424.
Sheppard WL, Mosich GM, Smith RA, Hamad CD, Park HY, Zoller SD, Trikha R, McCoy TK, Borthwell R, Hoang J, Truong N, Cevallos N, Clarkson S, Hori KR, van Dijl JM, Francis KP, Petrigliano FA, Bernthal NM. PMID: 32014357.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Preclinical Models and Methodologies for Monitoring Staphylococcus aureus Infections Using Noninvasive Optical Imaging. Methods Mol Biol. 2020; 2069:197-228.
Archer NK, Wang Y, Ortines RV, Liu H, Nolan SJ, Liu Q, Alphonse MP, Dikeman DA, Mazhar M, Miller RJ, Anderson LS, Francis KP, Simon SI, Miller LS. PMID: 31523776; PMCID: PMC7745539.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
Bacterial adhesion inhibitor prevents infection in a rodent surgical incision model. Virulence. 2020 01 01; 11(1):695-706.
Huebinger RM, Do DH, Carlson DL, Yao X, Stones DH, De Souza Santos M, Vaz DP, Keen E, Wolf SE, Minei JP, Francis KP, Orth K, Krachler AM. PMID: 32490711; PMCID: PMC7550027.
View in:
PubMed Mentions: Fields:
Translation:
Animals
-
Development of a Staphylococcus aureus reporter strain with click beetle red luciferase for enhanced in vivo imaging of experimental bacteremia and mixed infections. Sci Rep. 2019 11 13; 9(1):16663.
Miller RJ, Crosby HA, Schilcher K, Wang Y, Ortines RV, Mazhar M, Dikeman DA, Pinsker BL, Brown ID, Joyce DP, Zhang J, Archer NK, Liu H, Alphonse MP, Czupryna J, Anderson WR, Bernthal NM, Fortuno-Miranda L, Bulte JWM, Francis KP, Horswill AR, Miller LS. PMID: 31723175; PMCID: PMC6853927.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice. Commun Biol. 2019; 2:326.
Miyazaki T, Gharib SA, Hsu YA, Xu K, Khodakivskyi P, Kobayashi A, Paragas J, Klose AD, Francis KP, Dubikovskaya E, Page-McCaw PS, Barasch J, Paragas N. PMID: 31508501; PMCID: PMC6718519.
View in:
PubMed Mentions:
7 Translation:
AnimalsCells
-
Corrigendum: Elevated Gut Microbiome-Derived Propionate Levels Are Associated With Reduced Sterile Lung Inflammation and Bacterial Immunity in Mice. Front Microbiol. 2019; 10:518.
Tian X, Hellman J, Horswill AR, Crosby HA, Francis KP, Prakash A. PMID: 30972040; PMCID: PMC6443955.
View in:
PubMed Mentions:
-
Elevated Gut Microbiome-Derived Propionate Levels Are Associated With Reduced Sterile Lung Inflammation and Bacterial Immunity in Mice. Front Microbiol. 2019; 10:159.
Tian X, Hellman J, Horswill AR, Crosby HA, Francis KP, Prakash A. PMID: 30891007; PMCID: PMC6413706.
View in:
PubMed Mentions:
28
-
Multimodal imaging guides surgical management in a preclinical spinal implant infection model. JCI Insight. 2019 Feb 07; 4(3).
Zoller SD, Park HY, Olafsen T, Zamilpa C, Burke ZD, Blumstein G, Sheppard WL, Hamad CD, Hori KR, Tseng JC, Czupryna J, McMannus C, Lee JT, Bispo M, Romero Pastrana F, Raineri EJ, Miller JF, Miller LS, van Dijl JM, Francis KP, Bernthal NM. PMID: 30728332; PMCID: PMC6413782.
View in:
PubMed Mentions:
10 Fields:
-
Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice. J Vis Exp. 2019 01 07; (143).
Gastelum G, Chang EY, Shackleford D, Bernthal N, Kraut J, Francis K, Smutko V, Frost P. PMID: 30663654; PMCID: PMC9202028.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
-
Mouse model of Gram-negative prosthetic joint infection reveals therapeutic targets. JCI Insight. 2018 09 06; 3(17).
Thompson JM, Miller RJ, Ashbaugh AG, Dillen CA, Pickett JE, Wang Y, Ortines RV, Sterling RS, Francis KP, Bernthal NM, Cohen TS, Tkaczyk C, Yu L, Stover CK, DiGiandomenico A, Sellman BR, Thorek DL, Miller LS. PMID: 30185667; PMCID: PMC6171808.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer. J Vis Exp. 2018 07 21; (137).
Momcilovic M, Bailey ST, Lee JT, Zamilpa C, Jones A, Abdelhady G, Mansfield J, Francis KP, Shackelford DB. PMID: 30080208; PMCID: PMC6126521.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
-
Can 3D imaging provide insights into spatial variations in bacterial infection patterns? Future Microbiol. 2018 06 01; 13:897-901.
Taylor PW, Francis KP. PMID: 29877113.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
Noninvasive optical and nuclear imaging of Staphylococcus-specific infection with a human monoclonal antibody-based probe. Virulence. 2018 01 01; 9(1):262-272.
Romero Pastrana F, Thompson JM, Heuker M, Hoekstra H, Dillen CA, Ortines RV, Ashbaugh AG, Pickett JE, Linssen MD, Bernthal NM, Francis KP, Buist G, van Oosten M, van Dam GM, Thorek DLJ, Miller LS, van Dijl JM. PMID: 29166841; PMCID: PMC5955194.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
-
NLRP3 Inflammasome Mediates Dormant Neutrophil Recruitment following Sterile Lung Injury and Protects against Subsequent Bacterial Pneumonia in Mice. Front Immunol. 2017; 8:1337.
Tian X, Sun H, Casbon AJ, Lim E, Francis KP, Hellman J, Prakash A. PMID: 29163464; PMCID: PMC5671513.
View in:
PubMed Mentions:
14 Fields:
-
Development of a Click Beetle Luciferase Reporter System for Enhanced Bioluminescence Imaging of Listeria monocytogenes: Analysis in Cell Culture and Murine Infection Models. Front Microbiol. 2017; 8:1797.
Ur Rahman S, Stanton M, Casey PG, Spagnuolo A, Bensi G, Hill C, Francis KP, Tangney M, Gahan CGM. PMID: 29018414; PMCID: PMC5622934.
View in:
PubMed Mentions:
10
-
Non-invasive three-dimensional imaging of Escherichia coli K1 infection using diffuse light imaging tomography combined with micro-computed tomography. Methods. 2017 08 15; 127:62-68.
Witcomb LA, Czupryna J, Francis KP, Frankel G, Taylor PW. PMID: 28522324.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Combinatory antibiotic therapy increases rate of bacterial kill but not final outcome in a novel mouse model of Staphylococcus aureus spinal implant infection. PLoS One. 2017; 12(2):e0173019.
Hu Y, Hegde V, Johansen D, Loftin AH, Dworsky E, Zoller SD, Park HY, Hamad CD, Nelson GE, Francis KP, Scaduto A, Bernthal NM. PMID: 28245229; PMCID: PMC5330510.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Preclinical Evaluation of Photoacoustic Imaging as a Novel Noninvasive Approach to Detect an Orthopaedic Implant Infection. J Am Acad Orthop Surg. 2017 Feb; 25 Suppl 1:S7-S12.
Wang Y, Thompson JM, Ashbaugh AG, Khodakivskyi P, Budin G, Sinisi R, Heinmiller A, van Oosten M, van Dijl JM, van Dam GM, Francis KP, Bernthal NM, Dubikovskaya EA, Miller LS. PMID: 27941556; PMCID: PMC6056014.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
Novel in vivo mouse model of implant related spine infection. J Orthop Res. 2017 01; 35(1):193-199.
Dworsky EM, Hegde V, Loftin AH, Richman S, Hu Y, Lord E, Francis KP, Miller LS, Wang JC, Scaduto A, Bernthal NM. PMID: 27116085; PMCID: PMC5268448.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Application of Fluorescent Protein Expressing Strains to Evaluation of Anti-Tuberculosis Therapeutic Efficacy In Vitro and In Vivo. PLoS One. 2016; 11(3):e0149972.
Kong Y, Yang D, Cirillo SL, Li S, Akin A, Francis KP, Maloney T, Cirillo JD. PMID: 26934495; PMCID: PMC4774912.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
In Vivo Bioluminescence Imaging of Intratumoral Bacteria. Methods Mol Biol. 2016; 1409:69-77.
Cronin M, Akin AR, Francis KP, Tangney M. PMID: 26846803.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Multi-Modal Imaging with a Toolbox of Influenza A Reporter Viruses. Viruses. 2015 Oct 13; 7(10):5319-27.
Tran V, Poole DS, Jeffery JJ, Sheahan TP, Creech D, Yevtodiyenko A, Peat AJ, Francis KP, You S, Mehle A. PMID: 26473913; PMCID: PMC4632381.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Development of a Bioluminescent Nitroreductase Probe for Preclinical Imaging. PLoS One. 2015; 10(6):e0131037.
Vorobyeva AG, Stanton M, Godinat A, Lund KB, Karateev GG, Francis KP, Allen E, Gelovani JG, McCormack E, Tangney M, Dubikovskaya EA. PMID: 26110789; PMCID: PMC4482324.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
-
Targeted imaging of bacterial infections: advances, hurdles and hopes. FEMS Microbiol Rev. 2015 Nov; 39(6):892-916.
van Oosten M, Hahn M, Crane LM, Pleijhuis RG, Francis KP, van Dijl JM, van Dam GM. PMID: 26109599.
View in:
PubMed Mentions:
38 Fields:
Translation:
Humans
-
Combined in vivo optical and µCT imaging to monitor infection, inflammation, and bone anatomy in an orthopaedic implant infection in mice. J Vis Exp. 2014 Oct 16; (92):e51612.
Bernthal NM, Taylor BN, Meganck JA, Wang Y, Shahbazian JH, Niska JA, Francis KP, Miller LS. PMID: 25350287; PMCID: PMC4480817.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Real-time bioluminescence imaging of mixed mycobacterial infections. PLoS One. 2014; 9(9):e108341.
Chang M, Anttonen KP, Cirillo SL, Francis KP, Cirillo JD. PMID: 25265287; PMCID: PMC4180448.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Azithromycin inhibits nuclear factor-κB activation during lung inflammation: an in vivo imaging study. Pharmacol Res Perspect. 2014 Oct; 2(5):e00058.
Stellari FF, Sala A, Donofrio G, Ruscitti F, Caruso P, Topini TM, Francis KP, Li X, Carnini C, Civelli M, Villetti G. PMID: 25505605; PMCID: PMC4186419.
View in:
PubMed Mentions:
24 Fields:
-
Efficacy of enrofloxacin in a mouse model of sepsis. J Am Assoc Lab Anim Sci. 2014 Jul; 53(4):381-6.
Slate AR, Bandyopadhyay S, Francis KP, Papich MG, Karolewski B, Hod EA, Prestia KA. PMID: 25199094; PMCID: PMC4113238.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
α-Intercalated cells defend the urinary system from bacterial infection. J Clin Invest. 2014 Jul; 124(7):2963-76.
Paragas N, Kulkarni R, Werth M, Schmidt-Ott KM, Forster C, Deng R, Zhang Q, Singer E, Klose AD, Shen TH, Francis KP, Ray S, Vijayakumar S, Seward S, Bovino ME, Xu K, Takabe Y, Amaral FE, Mohan S, Wax R, Corbin K, Sanna-Cherchi S, Mori K, Johnson L, Nickolas T, D'Agati V, Lin CS, Qiu A, Al-Awqati Q, Ratner AJ, Barasch J. PMID: 24937428; PMCID: PMC4071397.
View in:
PubMed Mentions:
88 Fields:
Translation:
HumansAnimalsCells
-
Transfusion of stored blood impairs host defenses against Gram-negative pathogens in mice. Transfusion. 2014 Nov; 54(11):2842-51.
Prestia K, Bandyopadhyay S, Slate A, Francis RO, Francis KP, Spitalnik SL, Fidock DA, Brittenham GM, Hod EA. PMID: 24840185; PMCID: PMC4229414.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
-
Opening up the optical imaging window using nano-luciferin. Pharm Res. 2014 Nov; 31(11):3073-84.
Patel AR, Lim E, Francis KP, Singh M. PMID: 24831312; PMCID: PMC4214878.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
-
Microbiota of human breast tissue. Appl Environ Microbiol. 2014 May; 80(10):3007-14.
Urbaniak C, Cummins J, Brackstone M, Macklaim JM, Gloor GB, Baban CK, Scott L, O'Hanlon DM, Burton JP, Francis KP, Tangney M, Reid G. PMID: 24610844; PMCID: PMC4018903.
View in:
PubMed Mentions:
195 Fields:
Translation:
HumansCells
-
Combination prophylactic therapy with rifampin increases efficacy against an experimental Staphylococcus epidermidis subcutaneous implant-related infection. Antimicrob Agents Chemother. 2014; 58(4):2377-86.
Stavrakis AI, Niska JA, Shahbazian JH, Loftin AH, Ramos RI, Billi F, Francis KP, Otto M, Bernthal NM, Uslan DZ, Miller LS. PMID: 24514089; PMCID: PMC4023771.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Theranostic tumor homing nanocarriers for the treatment of lung cancer. Nanomedicine. 2014 Jul; 10(5):1053-63.
Patel AR, Chougule MB, Lim E, Francis KP, Safe S, Singh M. PMID: 24355163; PMCID: PMC4061286.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
-
4D multimodality imaging of Citrobacter rodentium infections in mice. J Vis Exp. 2013 Aug 13; (78).
Collins JW, Meganck JA, Kuo C, Francis KP, Frankel G. PMID: 23979310; PMCID: PMC3855914.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Vancomycin-rifampin combination therapy has enhanced efficacy against an experimental Staphylococcus aureus prosthetic joint infection. Antimicrob Agents Chemother. 2013 Oct; 57(10):5080-6.
Niska JA, Shahbazian JH, Ramos RI, Francis KP, Bernthal NM, Miller LS. PMID: 23917317; PMCID: PMC3811477.
View in:
PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Use of optical imaging to progress novel therapeutics to the clinic. J Control Release. 2013 Dec 10; 172(2):523-34.
Byrne WL, DeLille A, Kuo C, de Jong JS, van Dam GM, Francis KP, Tangney M. PMID: 23680286.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
Enhanced detection of myeloperoxidase activity in deep tissues through luminescent excitation of near-infrared nanoparticles. Nat Med. 2013 Apr; 19(4):500-5.
Zhang N, Francis KP, Prakash A, Ansaldi D. PMID: 23455711.
View in:
PubMed Mentions:
33 Fields:
Translation:
Animals
-
Real-time in vivo imaging of invasive- and biomaterial-associated bacterial infections using fluorescently labelled vancomycin. Nat Commun. 2013; 4:2584.
van Oosten M, Schäfer T, Gazendam JA, Ohlsen K, Tsompanidou E, de Goffau MC, Harmsen HJ, Crane LM, Lim E, Francis KP, Cheung L, Olive M, Ntziachristos V, van Dijl JM, van Dam GM. PMID: 24129412.
View in:
PubMed Mentions:
85 Fields:
Translation:
HumansAnimalsCells
-
Bioluminescent bacterial imaging in vivo. J Vis Exp. 2012 Nov 04; (69):e4318.
Baban CK, Cronin M, Akin AR, O'Brien A, Gao X, Tabirca S, Francis KP, Tangney M. PMID: 23149597; PMCID: PMC3578263.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
Monitoring bacterial burden, inflammation and bone damage longitudinally using optical and μCT imaging in an orthopaedic implant infection in mice. PLoS One. 2012; 7(10):e47397.
Niska JA, Meganck JA, Pribaz JR, Shahbazian JH, Lim E, Zhang N, Rice BW, Akin A, Ramos RI, Bernthal NM, Francis KP, Miller LS. PMID: 23082163; PMCID: PMC3474799.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
-
Bacterial vectors for imaging and cancer gene therapy: a review. Cancer Gene Ther. 2012 Nov; 19(11):731-40.
Cronin M, Stanton RM, Francis KP, Tangney M. PMID: 22996740.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
-
Pre-treatment with Bifidobacterium breve UCC2003 modulates Citrobacter rodentium-induced colonic inflammation and organ specificity. Microbiology (Reading). 2012 Nov; 158(Pt 11):2826-2834.
Collins JW, Akin AR, Kosta A, Zhang N, Tangney M, Francis KP, Frankel G. PMID: 22902730; PMCID: PMC3541765.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Daptomycin and tigecycline have broader effective dose ranges than vancomycin as prophylaxis against a Staphylococcus aureus surgical implant infection in mice. Antimicrob Agents Chemother. 2012 May; 56(5):2590-7.
Niska JA, Shahbazian JH, Ramos RI, Pribaz JR, Billi F, Francis KP, Miller LS. PMID: 22371896; PMCID: PMC3346658.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
-
In vivo optical imaging in gene & cell therapy. Curr Gene Ther. 2012 Feb 01; 12(1):2-11.
Tangney M, Francis KP. PMID: 22263919.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimals
-
High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting. PLoS One. 2012; 7(1):e30940.
Cronin M, Akin AR, Collins SA, Meganck J, Kim JB, Baban CK, Joyce SA, van Dam GM, Zhang N, van Sinderen D, O'Sullivan GC, Kasahara N, Gahan CG, Francis KP, Tangney M. PMID: 22295120; PMCID: PMC3266281.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
-
Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps. J Immunol. 2012 Mar 01; 188(5):2316-27.
Yan J, Meng X, Wancket LM, Lintner K, Nelin LD, Chen B, Francis KP, Smith CV, Rogers LK, Liu Y. PMID: 22279102; PMCID: PMC3480216.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
-
Imaging pulmonary NF-kappaB activation and therapeutic effects of MLN120B and TDZD-8. PLoS One. 2011; 6(9):e25093.
Ansaldi D, Hod EA, Stellari F, Kim JB, Lim E, Roskey M, Francis KP, Singh R, Zhang N. PMID: 21966423; PMCID: PMC3178604.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
-
Mouse model of chronic post-arthroplasty infection: noninvasive in vivo bioluminescence imaging to monitor bacterial burden for long-term study. J Orthop Res. 2012 Mar; 30(3):335-40.
Pribaz JR, Bernthal NM, Billi F, Cho JS, Ramos RI, Guo Y, Cheung AL, Francis KP, Miller LS. PMID: 21837686; PMCID: PMC3217109.
View in:
PubMed Mentions:
78 Fields:
Translation:
AnimalsCells
-
Visualization of plant viral suppressor silencing activity in intact leaf lamina by quantitative fluorescent imaging. Plant Methods. 2011 Aug 03; 7:25.
Stephan D, Slabber C, George G, Ninov V, Francis KP, Burger JT. PMID: 21812965; PMCID: PMC3163223.
View in:
PubMed Mentions:
5
-
Whole-body imaging of infection using bioluminescence. Curr Protoc Microbiol. 2011 May; Chapter 2:Unit 2C.4.
Kong Y, Shi Y, Chang M, Akin AR, Francis KP, Zhang N, Troy TL, Yao H, Rao J, Cirillo SL, Cirillo JD. PMID: 21538305; PMCID: PMC4540481.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
Whole-body imaging of infection using fluorescence. Curr Protoc Microbiol. 2011 May; Chapter 2:Unit 2C.3.
Kong Y, Akin AR, Francis KP, Zhang N, Troy TL, Xie H, Rao J, Cirillo SL, Cirillo JD. PMID: 21538304.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Protective role of IL-1β against post-arthroplasty Staphylococcus aureus infection. J Orthop Res. 2011 Oct; 29(10):1621-6.
Bernthal NM, Pribaz JR, Stavrakis AI, Billi F, Cho JS, Ramos RI, Francis KP, Iwakura Y, Miller LS. PMID: 21445990; PMCID: PMC3132302.
View in:
PubMed Mentions:
45 Fields:
Translation:
AnimalsCells
-
In vivo sodium concentration continuously monitored with fluorescent sensors. Integr Biol (Camb). 2011 Feb; 3(2):142-8.
Dubach JM, Lim E, Zhang N, Francis KP, Clark H. PMID: 21088796.
View in:
PubMed Mentions:
20 Fields:
Translation:
Animals
-
The risk of biomaterial-associated infection after revision surgery due to an experimental primary implant infection. Biofouling. 2010 Oct; 26(7):761-7.
Engelsman AF, Saldarriaga-Fernandez IC, Nejadnik MR, van Dam GM, Francis KP, Ploeg RJ, Busscher HJ, van der Mei HC. PMID: 20737327.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCellsPHPublic Health
-
Fluorescent nano-optodes for glucose detection. Anal Chem. 2010 May 01; 82(9):3707-13.
Billingsley K, Balaconis MK, Dubach JM, Zhang N, Lim E, Francis KP, Clark HA. PMID: 20355725; PMCID: PMC2862111.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation. Blood. 2010 May 27; 115(21):4284-92.
Hod EA, Zhang N, Sokol SA, Wojczyk BS, Francis RO, Ansaldi D, Francis KP, Della-Latta P, Whittier S, Sheth S, Hendrickson JE, Zimring JC, Brittenham GM, Spitalnik SL. PMID: 20299509; PMCID: PMC2879099.
View in:
PubMed Mentions:
213 Fields:
Translation:
HumansAnimals
-
Measuring prions by bioluminescence imaging. Proc Natl Acad Sci U S A. 2009 Sep 01; 106(35):15002-6.
Tamgüney G, Francis KP, Giles K, Lemus A, DeArmond SJ, Prusiner SB. PMID: 19706444; PMCID: PMC2736416.
View in:
PubMed Mentions:
38 Fields:
Translation:
Animals
-
Real time noninvasive monitoring of contaminating bacteria in a soft tissue implant infection model. J Biomed Mater Res B Appl Biomater. 2009 Jan; 88(1):123-9.
Engelsman AF, van der Mei HC, Francis KP, Busscher HJ, Ploeg RJ, van Dam GM. PMID: 18618733.
View in:
PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
-
Bioluminescent imaging of bacterial biofilm infections in vivo. Methods Mol Biol. 2008; 431:225-39.
Kadurugamuwa JL, Francis KP. PMID: 18287760.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Expression of firefly luciferase in Candida albicans and its use in the selection of stable transformants. Microb Pathog. 2006 Feb; 40(2):69-81.
Doyle TC, Nawotka KA, Purchio AF, Akin AR, Francis KP, Contag PR. PMID: 16427765.
View in:
PubMed Mentions:
15 Fields:
Translation:
Animals
-
Visualizing fungal infections in living mice using bioluminescent pathogenic Candida albicans strains transformed with the firefly luciferase gene. Microb Pathog. 2006 Feb; 40(2):82-90.
Doyle TC, Nawotka KA, Kawahara CB, Francis KP, Contag PR. PMID: 16426810.
View in:
PubMed Mentions:
35 Fields:
Translation:
Animals
-
Monitoring photodynamic therapy of localized infections by bioluminescence imaging of genetically engineered bacteria. J Photochem Photobiol B. 2005 Oct 03; 81(1):15-25.
Demidova TN, Gad F, Zahra T, Francis KP, Hamblin MR. PMID: 16040251; PMCID: PMC3071690.
View in:
PubMed Mentions:
56 Fields:
Translation:
Animals
-
Noninvasive biophotonic imaging for monitoring of catheter-associated urinary tract infections and therapy in mice. Infect Immun. 2005 Jul; 73(7):3878-87.
Kadurugamuwa JL, Modi K, Yu J, Francis KP, Purchio T, Contag PR. PMID: 15972473; PMCID: PMC1168591.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
-
Noninvasive monitoring of pneumococcal meningitis and evaluation of treatment efficacy in an experimental mouse model. Mol Imaging. 2005 Apr-Jun; 4(2):137-42.
Kadurugamuwa JL, Modi K, Yu J, Francis KP, Orihuela C, Tuomanen E, Purchio AF, Contag PR. PMID: 16105511.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Monitoring in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm infection model. J Antimicrob Chemother. 2005 Apr; 55(4):528-34.
Yu J, Wu J, Francis KP, Purchio TF, Kadurugamuwa JL. PMID: 15743898.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Real-time in vivo bioluminescent imaging for evaluating the efficacy of antibiotics in a rat Staphylococcus aureus endocarditis model. Antimicrob Agents Chemother. 2005 Jan; 49(1):380-7.
Xiong YQ, Willard J, Kadurugamuwa JL, Yu J, Francis KP, Bayer AS. PMID: 15616318; PMCID: PMC538900.
View in:
PubMed Mentions:
56 Fields:
Translation:
HumansAnimalsCells
-
Tissue-specific contributions of pneumococcal virulence factors to pathogenesis. J Infect Dis. 2004 Nov 01; 190(9):1661-9.
Orihuela CJ, Gao G, Francis KP, Yu J, Tuomanen EI. PMID: 15478073.
View in:
PubMed Mentions:
162 Fields:
Translation:
AnimalsCells
-
Noninvasive optical imaging method to evaluate postantibiotic effects on biofilm infection in vivo. Antimicrob Agents Chemother. 2004 Jun; 48(6):2283-7.
Kadurugamuwa JL, Sin LV, Yu J, Francis KP, Purchio TF, Contag PR. PMID: 15155235; PMCID: PMC415634.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
-
Targeted photodynamic therapy of established soft-tissue infections in mice. Photochem Photobiol Sci. 2004 May; 3(5):451-8.
Gad F, Zahra T, Francis KP, Hasan T, Hamblin MR. PMID: 15122362; PMCID: PMC3071693.
View in:
PubMed Mentions:
54 Fields:
Translation:
Animals
-
Extracellular replication of Listeria monocytogenes in the murine gall bladder. Science. 2004 Feb 06; 303(5659):851-3.
Hardy J, Francis KP, DeBoer M, Chu P, Gibbs K, Contag CH. PMID: 14764883.
View in:
PubMed Mentions:
111 Fields:
Translation:
AnimalsCells
-
The AGUAAA motif in cspA1/A2 mRNA is important for adaptation of Yersinia enterocolitica to grow at low temperature. Mol Microbiol. 2003 Dec; 50(5):1629-45.
Neuhaus K, Anastasov N, Kaberdin V, Francis KP, Miller VL, Scherer S. PMID: 14651644.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Rapid direct method for monitoring antibiotics in a mouse model of bacterial biofilm infection. Antimicrob Agents Chemother. 2003 Oct; 47(10):3130-7.
Kadurugamuwa JL, Sin LV, Yu J, Francis KP, Kimura R, Purchio T, Contag PR. PMID: 14506020; PMCID: PMC201124.
View in:
PubMed Mentions:
41 Fields:
Translation:
AnimalsCells
-
Real-time monitoring of bacterial infection in vivo: development of bioluminescent staphylococcal foreign-body and deep-thigh-wound mouse infection models. Antimicrob Agents Chemother. 2003 Sep; 47(9):2740-8.
Kuklin NA, Pancari GD, Tobery TW, Cope L, Jackson J, Gill C, Overbye K, Francis KP, Yu J, Montgomery D, Anderson AS, McClements W, Jansen KU. PMID: 12936968; PMCID: PMC182637.
View in:
PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
-
Membranous cells in nasal-associated lymphoid tissue: a portal of entry for the respiratory mucosal pathogen group A streptococcus. J Immunol. 2003 Sep 01; 171(5):2532-7.
Park HS, Francis KP, Yu J, Cleary PP. PMID: 12928403.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansAnimalsCells
-
Direct continuous method for monitoring biofilm infection in a mouse model. Infect Immun. 2003 02; 71(2):882-90.
Kadurugamuwa JL, Sin L, Albert E, Yu J, Francis K, DeBoer M, Rubin M, Bellinger-Kawahara C, Parr TR, Contag PR. PMID: 12540570; PMCID: PMC145362.
View in:
PubMed Mentions:
95 Fields:
Translation:
HumansAnimalsCells
-
Organ-specific models of Streptococcus pneumoniae disease. Scand J Infect Dis. 2003; 35(9):647-52.
Orihuela CJ, Gao G, McGee M, Yu J, Francis KP, Tuomanen E. PMID: 14620149.
View in:
PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
-
Sensitive in situ monitoring of a recombinant bioluminescent Yersinia enterocolitica reporter mutant in real time on Camembert cheese. Appl Environ Microbiol. 2002 Nov; 68(11):5737-40.
Maoz A, Mayr R, Bresolin G, Neuhaus K, Francis KP, Scherer S. PMID: 12406772; PMCID: PMC129901.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
-
Pyridinyl polythiazole class peptide antibiotic micrococcin P1, secreted by foodborne Staphylococcus equorum WS2733, is biosynthesized nonribosomally. Eur J Biochem. 2001 Dec; 268(24):6390-401.
Carnio MC, Stachelhaus T, Francis KP, Scherer S. PMID: 11737193.
View in:
PubMed Mentions:
12 Fields:
Translation:
Cells
-
Visualizing pneumococcal infections in the lungs of live mice using bioluminescent Streptococcus pneumoniae transformed with a novel gram-positive lux transposon. Infect Immun. 2001 May; 69(5):3350-8.
Francis KP, Yu J, Bellinger-Kawahara C, Joh D, Hawkinson MJ, Xiao G, Purchio TF, Caparon MG, Lipsitch M, Contag PR. PMID: 11292758; PMCID: PMC98294.
View in:
PubMed Mentions:
121 Fields:
Translation:
AnimalsCells
-
Revealing the spatiotemporal patterns of bacterial infectious diseases using bioluminescent pathogens and whole body imaging. Contrib Microbiol. 2001; 9:71-88.
Burns SM, Joh D, Francis KP, Shortliffe LD, Gruber CA, Contag PR, Contag CH. PMID: 11764723.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
-
Changes in cspL, cspP, and cspC mRNA abundance as a function of cold shock and growth phase in Lactobacillus plantarum. J Bacteriol. 2000 Sep; 182(18):5105-13.
Derzelle S, Hallet B, Francis KP, Ferain T, Delcour J, Hols P. PMID: 10960094; PMCID: PMC94658.
View in:
PubMed Mentions:
24 Fields:
Translation:
Cells
-
Monitoring bioluminescent Staphylococcus aureus infections in living mice using a novel luxABCDE construct. Infect Immun. 2000 Jun; 68(6):3594-600.
Francis KP, Joh D, Bellinger-Kawahara C, Hawkinson MJ, Purchio TF, Contag PR. PMID: 10816517; PMCID: PMC97648.
View in:
PubMed Mentions:
157 Fields:
Translation:
AnimalsCells
-
Restart of exponential growth of cold-shocked Yersinia enterocolitica occurs after down-regulation of cspA1/A2 mRNA. J Bacteriol. 2000 Jun; 182(11):3285-8.
Neuhaus K, Rapposch S, Francis KP, Scherer S. PMID: 10809713; PMCID: PMC94520.
View in:
PubMed Mentions:
19 Fields:
Translation:
Cells
-
Pathogenic Yersinia species carry a novel, cold-inducible major cold shock protein tandem gene duplication producing both bicistronic and monocistronic mRNA. J Bacteriol. 1999 Oct; 181(20):6449-55.
Neuhaus K, Francis KP, Rapposch S, Görg A, Scherer S. PMID: 10515936; PMCID: PMC103781.
View in:
PubMed Mentions:
9 Fields:
Translation:
Cells
-
Correlation of 16S ribosomal DNA signature sequences with temperature-dependent growth rates of mesophilic and psychrotolerant strains of the Bacillus cereus group. J Bacteriol. 1999 Apr; 181(8):2624-30.
Prüss BM, Francis KP, von Stetten F, Scherer S. PMID: 10198030; PMCID: PMC93692.
View in:
PubMed Mentions:
20 Fields:
Translation:
CellsPHPublic Health
-
Bacillus weihenstephanensis sp. nov. is a new psychrotolerant species of the Bacillus cereus group. Int J Syst Bacteriol. 1998 Oct; 48 Pt 4:1373-82.
Lechner S, Mayr R, Francis KP, Prüss BM, Kaplan T, Wiessner-Gunkel E, Stewart GS, Scherer S. PMID: 9828439.
View in:
PubMed Mentions:
99 Fields:
Translation:
AnimalsCells
-
Discrimination of psychrotrophic and mesophilic strains of the Bacillus cereus group by PCR targeting of major cold shock protein genes. Appl Environ Microbiol. 1998 Sep; 64(9):3525-9.
Francis KP, Mayr R, von Stetten F, Stewart GS, Scherer S. PMID: 9726910; PMCID: PMC106760.
View in:
PubMed Mentions:
22 Fields:
Translation:
CellsPHPublic Health
-
Expression of the cold-shock gene cspB in Salmonella typhimurium occurs below a threshold temperature. Microbiology (Reading). 1998 Mar; 144 ( Pt 3):697-704.
Craig JE, Boyle D, Francis KP, Gallagher MP. PMID: 9534239.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Detection and speciation of bacteria through PCR using universal major cold-shock protein primer oligomers. J Ind Microbiol Biotechnol. 1997 Oct; 19(4):286-93.
Francis KP, Stewart GS. PMID: 9439003.
View in:
PubMed Mentions:
14 Fields:
Translation:
Cells
-
Identification of the ahp operon of Salmonella typhimurium as a macrophage-induced locus. J Bacteriol. 1997 Jun; 179(12):4046-8.
Francis KP, Taylor PD, Inchley CJ, Gallagher MP. PMID: 9190824; PMCID: PMC179217.
View in:
PubMed Mentions:
8 Fields:
Translation:
Cells
-
Light emission from a Mudlux transcriptional fusion in Salmonella typhimurium is stimulated by hydrogen peroxide and by interaction with the mouse macrophage cell line J774.2. Infect Immun. 1993 Feb; 61(2):640-9.
Francis KP, Gallagher MP. PMID: 8423094; PMCID: PMC302775.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells