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Adams, John S

Title(s)Professor, Orthopaedic Surgery
Phone75585, Adm 51394
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    Other Positions
    Title(s)Professor, Medicine


    Collapse Research 
    Collapse Research Activities and Funding
    Impact of ethnicity in the gut microbiome in response to oral vitamin D replacement
    NIH/NIAMS R21AR073018Sep 18, 2017 - Aug 31, 2018
    Role: Principal Investigator
    DBP and the bioavailability and function of vitamin D
    NIH/NIAMS R01AR063910Sep 1, 2013 - May 31, 2018
    Role: Principal Investigator
    Regenerative Musculoskeletal Medicine Training Program
    NIH/NIAMS T32AR059033Apr 1, 2010 - Jul 31, 2021
    Role: Principal Investigator
    Orthopaedic Wear Debris, Vitamin D, and Innate Immunity
    NIH/NIAMS R21AR056885Aug 1, 2009 - Jul 31, 2012
    Role: Principal Investigator
    Vitamin D and Barrier Function
    NIH/NIAMS R01AR050626Jul 26, 2004 - Nov 2, 2007
    Role: Co-Principal Investigator
    CO-FACILITATORS: NOVEL REGULATORS OF HORMONE METABOLISM
    NIH/NIDDK R01DK058891Sep 1, 2001 - Aug 31, 2006
    Role: Principal Investigator
    BISPHOSPHONATES AND EXTRAOSSEOUS CALCIFICATION
    NIH/NIAMS R01AR046231Sep 30, 1999 - Aug 31, 2003
    Role: Principal Investigator
    Vitamin D and Estrogen Action in Bone: Concerted Role for hnRNPs in the C Family
    NIH/NIAMS R01AR037399Apr 1, 1988 - Mar 31, 1993
    Role: Principal Investigator
    GENETICS OF FERRIC-TRANSFERRIN USE IN N. GONORRHOEAE
    NIH/NIAID F32AI007745Mar 31, 1988
    Role: Principal Investigator
    VITAMIN D METABOLISM IN SARCOIDOSIS
    NIH/NIAID R01AI040403Jul 1, 1985 - Mar 31, 2002
    Role: Principal Investigator
    VITAMIN D METABOLISM IN SARCOIDOSIS AND LYMPHOMA
    NIH/NIDDK R01DK033139Jul 1, 1985 - Jun 30, 1995
    Role: Principal Investigator
    METABOLISM OF 25-HYDROXYVITAMIN D3 BY PAM IN SARCOIDOSIS
    NIH/NIADDK R23AM033139Jul 1, 1985 - Jun 30, 1988
    Role: Principal Investigator
    METABOLISM OF 25-HYDROXYVITAMIN D3 BY PAM IN SARCOIDOSIS
    NIH/NIDDK R23DK033139Jul 1, 1985 - Jun 30, 1988
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Arshi A, Shieh A, Adams JS, Bernthal NM, Zeegen EN, Sassoon AA. Preoperative Vitamin D Repletion in Total Knee Arthroplasty: A Cost-Effectiveness Model. J Arthroplasty. 2019 Dec 27. PMID: 31983566.
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    2. Chun RF, Shieh A, Gottlieb C, Yacoubian V, Wang J, Hewison M, Adams JS. Vitamin D Binding Protein and the Biological Activity of Vitamin D. Front Endocrinol (Lausanne). 2019; 10:718. PMID: 31708871.
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    3. Li D, Jeffery LE, Jenkinson C, Harrison SR, Chun RF, Adams JS, Raza K, Hewison M. Serum and synovial fluid vitamin D metabolites and rheumatoid arthritis. J Steroid Biochem Mol Biol. 2019 03; 187:1-8. PMID: 30611909.
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    4. Zavala K, Gottlieb CA, Teles RM, Adams JS, Hewison M, Modlin RL, Liu PT. Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN. PLoS Negl Trop Dis. 2018 10; 12(10):e0006815. PMID: 30300363.
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    5. Shieh A, Ma C, Chun RF, Wittwer-Schegg J, Swinkels L, Huijs T, Wang J, Donangelo I, Hewison M, Adams JS. Associations Between Change in Total and Free 25-Hydroxyvitamin D With 24,25-Dihydroxyvitamin D and Parathyroid Hormone. J Clin Endocrinol Metab. 2018 09 01; 103(9):3368-3375. PMID: 29931358.
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    6. Hegde V, Dworsky EM, Stavrakis AI, Loftin AH, Zoller SD, Park HY, Richman S, Johansen D, Hu Y, Taylor JA, Hamad CD, Chun RF, Xi W, Adams JS, Bernthal NM. Single-Dose, Preoperative Vitamin-D Supplementation Decreases Infection in a Mouse Model of Periprosthetic Joint Infection. J Bone Joint Surg Am. 2017 Oct 18; 99(20):1737-1744. PMID: 29040128.
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    7. Shieh A, Ma C, Chun RF, Witzel S, Rafison B, Contreras HTM, Wittwer-Schegg J, Swinkels L, Huijs T, Hewison M, Adams JS. Effects of Cholecalciferol vs Calcifediol on Total and Free 25-Hydroxyvitamin D and Parathyroid Hormone. J Clin Endocrinol Metab. 2017 Apr 01; 102(4):1133-1140. PMID: 28187226.
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    8. Zhou R, Park JW, Chun RF, Lisse TS, Garcia AJ, Zavala K, Sea JL, Lu ZX, Xu J, Adams JS, Xing Y, Hewison M. Concerted effects of heterogeneous nuclear ribonucleoprotein C1/C2 to control vitamin D-directed gene transcription and RNA splicing in human bone cells. Nucleic Acids Res. 2017 01 25; 45(2):606-618. PMID: 27672039.
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    9. Chun RF, Hernandez I, Pereira R, Swinkles L, Huijs T, Zhou R, Liu NQ, Shieh A, Guemes M, Mallya SM, Adams JS, Hewison M. Differential Responses to Vitamin D2 and Vitamin D3 Are Associated With Variations in Free 25-Hydroxyvitamin D. Endocrinology. 2016 09; 157(9):3420-30. PMID: 27399876.
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    10. Shieh A, Chun RF, Ma C, Witzel S, Meyer B, Rafison B, Swinkels L, Huijs T, Pepkowitz S, Holmquist B, Hewison M, Adams JS. Effects of High-Dose Vitamin D2 Versus D3 on Total and Free 25-Hydroxyvitamin D and Markers of Calcium Balance. J Clin Endocrinol Metab. 2016 08; 101(8):3070-8. PMID: 27192696.
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    11. Nielson CM, Jones KS, Chun RF, Jacobs JM, Wang Y, Hewison M, Adams JS, Swanson CM, Lee CG, Vanderschueren D, Pauwels S, Prentice A, Smith RD, Shi T, Gao Y, Schepmoes AA, Zmuda JM, Lapidus J, Cauley JA, Bouillon R, Schoenmakers I, Orwoll ES. Free 25-Hydroxyvitamin D: Impact of Vitamin D Binding Protein Assays on Racial-Genotypic Associations. J Clin Endocrinol Metab. 2016 05; 101(5):2226-34. PMID: 27007693.
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    12. Nielson CM, Jones KS, Bouillon R, Chun RF, Jacobs J, Wang Y, Hewison M, Adams JS, Swanson CM, Lee CG, Vanderschueren D, Pauwels S, Prentice A, Smith RD, Shi T, Gao Y, Zmuda JM, Lapidus J, Cauley JA, Schoenmakers I, Orwoll ES. Role of Assay Type in Determining Free 25-Hydroxyvitamin D Levels in Diverse Populations. N Engl J Med. 2016 Apr 28; 374(17):1695-6. PMID: 27007809.
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    13. Jenkinson C, Taylor AE, Hassan-Smith ZK, Adams JS, Stewart PM, Hewison M, Keevil BG. High throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 01; 1014:56-63. PMID: 26874878.
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    14. James AW, Shen J, Zhang X, Asatrian G, Goyal R, Kwak JH, Jiang L, Bengs B, Culiat CT, Turner AS, Seim Iii HB, Wu BM, Lyons K, Adams JS, Ting K, Soo C. NELL-1 in the treatment of osteoporotic bone loss. Nat Commun. 2015 Jun 17; 6:7362. PMID: 26082355.
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    15. Zhou R, Chun RF, Lisse TS, Garcia AJ, Xu J, Adams JS, Hewison M. Vitamin D and alternative splicing of RNA. J Steroid Biochem Mol Biol. 2015 Apr; 148:310-7. PMID: 25447737.
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    16. Chun RF, Blatter E, Elliott S, Fitz-Gibbon S, Rieger S, Sagasti A, Adams JS, Hewison M. Cloning of a functional 25-hydroxyvitamin D-1a-hydroxylase in zebrafish (Danio rerio). Cell Biochem Funct. 2014 Dec; 32(8):675-82. PMID: 25290078.
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    17. Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, Bloom BR, Modlin RL. IL-32 is a molecular marker of a host defense network in human tuberculosis. Sci Transl Med. 2014 Aug 20; 6(250):250ra114. PMID: 25143364.
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    18. Chun RF, Liu NQ, Lee T, Schall JI, Denburg MR, Rutstein RM, Adams JS, Zemel BS, Stallings VA, Hewison M. Vitamin D supplementation and antibacterial immune responses in adolescents and young adults with HIV/AIDS. J Steroid Biochem Mol Biol. 2015 Apr; 148:290-7. PMID: 25092518.
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    19. Chun RF, Liu PT, Modlin RL, Adams JS, Hewison M. Impact of vitamin D on immune function: lessons learned from genome-wide analysis. Front Physiol. 2014; 5:151. PMID: 24795646.
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    20. Yuan FN, Valiyaparambil J, Woods MC, Tran H, Pant R, Adams JS, Mallya SM. Vitamin D signaling regulates oral keratinocyte proliferation in vitro and in vivo. Int J Oncol. 2014 May; 44(5):1625-33. PMID: 24626468.
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    21. Lisse TS, Vadivel K, Bajaj SP, Chun RF, Hewison M, Adams JS. The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1,25-dihydroxyvitamin D-directed transcriptional events in osteoblasts. Bone Res. 2014; 2. PMID: 25506471.
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    22. Adams JS, Rafison B, Witzel S, Reyes RE, Shieh A, Chun R, Zavala K, Hewison M, Liu PT. Regulation of the extrarenal CYP27B1-hydroxylase. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:22-7. PMID: 24388948.
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    23. Wu L, Bluguermann C, Kyupelyan L, Latour B, Gonzalez S, Shah S, Galic Z, Ge S, Zhu Y, Petrigliano FA, Nsair A, Miriuka SG, Li X, Lyons KM, Crooks GM, McAllister DR, Van Handel B, Adams JS, Evseenko D. Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells. Stem Cell Reports. 2013; 1(6):575-89. PMID: 24371811.
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    24. Chun RF, Peercy BE, Orwoll ES, Nielson CM, Adams JS, Hewison M. Vitamin D and DBP: the free hormone hypothesis revisited. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:132-7. PMID: 24095930.
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    25. Wu L, Gonzalez S, Shah S, Kyupelyan L, Petrigliano FA, McAllister DR, Adams JS, Karperien M, Tuan TL, Benya PD, Evseenko D. Extracellular matrix domain formation as an indicator of chondrocyte dedifferentiation and hypertrophy. Tissue Eng Part C Methods. 2014 Feb; 20(2):160-8. PMID: 23758619.
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    26. Lisse TS, Chun RF, Rieger S, Adams JS, Hewison M. Vitamin D activation of functionally distinct regulatory miRNAs in primary human osteoblasts. J Bone Miner Res. 2013 Jun; 28(6):1478-88. PMID: 23362149.
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    27. Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL. Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science. 2013 Mar 22; 339(6126):1448-53. PMID: 23449998.
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    28. Bacchetta J, Sea JL, Chun RF, Lisse TS, Wesseling-Perry K, Gales B, Adams JS, Salusky IB, Hewison M. Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes. J Bone Miner Res. 2013 Jan; 28(1):46-55. PMID: 22886720.
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    29. Lisse TS, Adams JS, Hewison M. Vitamin D and microRNAs in bone. Crit Rev Eukaryot Gene Expr. 2013; 23(3):195-214. PMID: 23879537.
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    30. Adams JS, Ramin J, Rafison B, Windon C, Windon A, Liu PT. Redefining Human Vitamin D Sufficiency: Back to the Basics. Bone Res. 2013; 1(1):2-10. PMID: 25285234.
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    31. Adams JS, Hewison M. Extrarenal expression of the 25-hydroxyvitamin D-1-hydroxylase. Arch Biochem Biophys. 2012 Jul 01; 523(1):95-102. PMID: 22446158.
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    32. Chun RF, Peercy BE, Adams JS, Hewison M. Vitamin D binding protein and monocyte response to 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D: analysis by mathematical modeling. PLoS One. 2012; 7(1):e30773. PMID: 22292037.
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    33. Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, Hollis BW, Hewison M, Adams JS, Steinmeyer A, Zügel U, Cheng G, Jo EK, Bloom BR, Modlin RL. Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Sci Transl Med. 2011 Oct 12; 3(104):104ra102. PMID: 21998409.
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    34. Chun RF, Adams JS, Hewison M. Immunomodulation by vitamin D: implications for TB. Expert Rev Clin Pharmacol. 2011 Sep; 4(5):583-91. PMID: 22046197.
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    35. Lake JE, Adams JS. Vitamin D in HIV-Infected Patients. Curr HIV/AIDS Rep. 2011 Sep; 8(3):133-41. PMID: 21647555.
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    36. Walker VP, Zhang X, Rastegar I, Liu PT, Hollis BW, Adams JS, Modlin RL. Cord blood vitamin D status impacts innate immune responses. J Clin Endocrinol Metab. 2011 Jun; 96(6):1835-43. PMID: 21470993.
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    37. Lisse TS, Hewison M, Adams JS. Hormone response element binding proteins: novel regulators of vitamin D and estrogen signaling. Steroids. 2011 Mar; 76(4):331-9. PMID: 21236284.
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    38. Edfeldt K, Liu PT, Chun R, Fabri M, Schenk M, Wheelwright M, Keegan C, Krutzik SR, Adams JS, Hewison M, Modlin RL. T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22593-8. PMID: 21149724.
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    39. Lisse TS, Liu T, Irmler M, Beckers J, Chen H, Adams JS, Hewison M. Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling. FASEB J. 2011 Mar; 25(3):937-47. PMID: 21123297.
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    40. Bernthal NM, Stavrakis AI, Billi F, Cho JS, Kremen TJ, Simon SI, Cheung AL, Finerman GA, Lieberman JR, Adams JS, Miller LS. A mouse model of post-arthroplasty Staphylococcus aureus joint infection to evaluate in vivo the efficacy of antimicrobial implant coatings. PLoS One. 2010 Sep 07; 5(9):e12580. PMID: 20830204.
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    41. Hokugo A, Christensen R, Chung EM, Sung EC, Felsenfeld AL, Sayre JW, Garrett N, Adams JS, Nishimura I. Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats. J Bone Miner Res. 2010 Jun; 25(6):1337-49. PMID: 20200938.
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    42. Lagishetty V, Misharin AV, Liu NQ, Lisse TS, Chun RF, Ouyang Y, McLachlan SM, Adams JS, Hewison M. Vitamin D deficiency in mice impairs colonic antibacterial activity and predisposes to colitis. Endocrinology. 2010 Jun; 151(6):2423-32. PMID: 20392825.
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    43. Lagishetty V, Chun RF, Liu NQ, Lisse TS, Adams JS, Hewison M. 1alpha-hydroxylase and innate immune responses to 25-hydroxyvitamin D in colonic cell lines. J Steroid Biochem Mol Biol. 2010 Jul; 121(1-2):228-33. PMID: 20152900.
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    44. Adams JS, Hewison M. Update in vitamin D. J Clin Endocrinol Metab. 2010 Feb; 95(2):471-8. PMID: 20133466.
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    45. Hewison M, Adams JS. Vitamin D insufficiency and skeletal development in utero. J Bone Miner Res. 2010 Jan; 25(1):11-3. PMID: 20091930.
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    46. Montoya D, Cruz D, Teles RM, Lee DJ, Ochoa MT, Krutzik SR, Chun R, Schenk M, Zhang X, Ferguson BG, Burdick AE, Sarno EN, Rea TH, Hewison M, Adams JS, Cheng G, Modlin RL. Divergence of macrophage phagocytic and antimicrobial programs in leprosy. Cell Host Microbe. 2009 Oct 22; 6(4):343-53. PMID: 19837374.
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    47. Adams JS, Ren S, Liu PT, Chun RF, Lagishetty V, Gombart AF, Borregaard N, Modlin RL, Hewison M. Vitamin d-directed rheostatic regulation of monocyte antibacterial responses. J Immunol. 2009 Apr 01; 182(7):4289-95. PMID: 19299728.
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    48. Chen H, Clemens TL, Hewison M, Adams JS. Estradiol and tamoxifen mediate rescue of the dominant-negative effects of estrogen response element-binding protein in vivo and in vitro. Endocrinology. 2009 May; 150(5):2429-35. PMID: 19106221.
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    49. Krutzik SR, Hewison M, Liu PT, Robles JA, Stenger S, Adams JS, Modlin RL. IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway. J Immunol. 2008 Nov 15; 181(10):7115-20. PMID: 18981132.
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    50. Lee JM, Pou K, Sadow PM, Chen H, Hu B, Hewison M, Adams JS, Sugarbaker DJ, Fisher ND. Vitamin D-mediated hypercalcemia and Cushing syndrome as manifestations of malignant pleural mesothelioma. Endocr Pract. 2008 Nov; 14(8):1011-6. PMID: 19095601.
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    51. Liu N, Nguyen L, Chun RF, Lagishetty V, Ren S, Wu S, Hollis B, DeLuca HF, Adams JS, Hewison M. Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation. Endocrinology. 2008 Oct; 149(10):4799-808. PMID: 18535110.
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    52. Chun RF, Adams JS, Hewison M. Back to the future: a new look at 'old' vitamin D. J Endocrinol. 2008 Aug; 198(2):261-9. PMID: 18495944.
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    53. Geller JL, Hu B, Reed S, Mirocha J, Adams JS. Increase in bone mass after correction of vitamin D insufficiency in bisphosphonate-treated patients. Endocr Pract. 2008 Apr; 14(3):293-7. PMID: 18463035.
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    54. Adams JS, Hewison M. Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab. 2008 Feb; 4(2):80-90. PMID: 18212810.
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    55. Chen H, Hewison M, Adams JS. Control of estradiol-directed gene transactivation by an intracellular estrogen-binding protein and an estrogen response element-binding protein. Mol Endocrinol. 2008 Mar; 22(3):559-69. PMID: 18096692.
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    56. Adams JS, Chen H, Chun R, Ren S, Wu S, Gacad M, Nguyen L, Ride J, Liu P, Modlin R, Hewison M. Substrate and enzyme trafficking as a means of regulating 1,25-dihydroxyvitamin D synthesis and action: the human innate immune response. J Bone Miner Res. 2007 Dec; 22 Suppl 2:V20-4. PMID: 18290716.
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    57. Adams JS, Liu PT, Chun R, Modlin RL, Hewison M. Vitamin D in defense of the human immune response. Ann N Y Acad Sci. 2007 Nov; 1117:94-105. PMID: 17656563.
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    58. Geller JL, Khosravi A, Kelly MH, Riminucci M, Adams JS, Collins MT. Cinacalcet in the management of tumor-induced osteomalacia. J Bone Miner Res. 2007 Jun; 22(6):931-7. PMID: 17352646.
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    59. Hewison M, Burke F, Evans KN, Lammas DA, Sansom DM, Liu P, Modlin RL, Adams JS. Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease. J Steroid Biochem Mol Biol. 2007 Mar; 103(3-5):316-21. PMID: 17368179.
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    60. Chen H, Hewison M, Adams JS. Functional characterization of heterogeneous nuclear ribonuclear protein C1/C2 in vitamin D resistance: a novel response element-binding protein. J Biol Chem. 2006 Dec 22; 281(51):39114-20. PMID: 17071612.
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    61. Karakelides H, Geller JL, Schroeter AL, Chen H, Behn PS, Adams JS, Hewison M, Wermers RA. Vitamin D-mediated hypercalcemia in slack skin disease: evidence for involvement of extrarenal 25-hydroxyvitamin D 1alpha-hydroxylase. J Bone Miner Res. 2006 Sep; 21(9):1496-9. PMID: 16939409.
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    62. Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science. 2006 Mar 24; 311(5768):1770-3. PMID: 16497887.
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    63. Adams JS. "Bound" to work: the free hormone hypothesis revisited. Cell. 2005 Sep 09; 122(5):647-9. PMID: 16143095.
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    64. Chun R, Gacad MA, Hewison M, Adams JS. Adenosine 5'-triphosphate-dependent vitamin D sterol binding to heat shock protein-70 chaperones. Endocrinology. 2005 Dec; 146(12):5540-4. PMID: 16141393.
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    65. Townsend K, Evans KN, Campbell MJ, Colston KW, Adams JS, Hewison M. Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment. J Steroid Biochem Mol Biol. 2005 Oct; 97(1-2):103-9. PMID: 16081283.
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    66. Chen H, Stuart W, Hu B, Nguyen L, Huang G, Clemens TL, Adams JS. Creation of estrogen resistance in vivo by transgenic overexpression of the heterogeneous nuclear ribonucleoprotein-related estrogen response element binding protein. Endocrinology. 2005 Oct; 146(10):4266-73. PMID: 15976060.
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    67. Ren S, Nguyen L, Wu S, Encinas C, Adams JS, Hewison M. Alternative splicing of vitamin D-24-hydroxylase: a novel mechanism for the regulation of extrarenal 1,25-dihydroxyvitamin D synthesis. J Biol Chem. 2005 May 27; 280(21):20604-11. PMID: 15788398.
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    68. Evans KN, Taylor H, Zehnder D, Kilby MD, Bulmer JN, Shah F, Adams JS, Hewison M. Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy. Am J Pathol. 2004 Sep; 165(3):807-13. PMID: 15331405.
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    69. Adams JS, Chen H, Chun R, Gacad MA, Encinas C, Ren S, Nguyen L, Wu S, Hewison M, Barsony J. Response element binding proteins and intracellular vitamin D binding proteins: novel regulators of vitamin D trafficking, action and metabolism. J Steroid Biochem Mol Biol. 2004 May; 89-90(1-5):461-5. PMID: 15225821.
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    70. Chen H, Hewison M, Hu B, Sharma M, Sun Z, Adams JS. An Hsp27-related, dominant-negative-acting intracellular estradiol-binding protein. J Biol Chem. 2004 Jul 16; 279(29):29944-51. PMID: 15123601.
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    71. Hewison M, Zehnder D, Chakraverty R, Adams JS. Vitamin D and barrier function: a novel role for extra-renal 1 alpha-hydroxylase. Mol Cell Endocrinol. 2004 Feb 27; 215(1-2):31-8. PMID: 15026172.
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    72. Chen H, Hewison M, Hu B, Adams JS. Heterogeneous nuclear ribonucleoprotein (hnRNP) binding to hormone response elements: a cause of vitamin D resistance. Proc Natl Acad Sci U S A. 2003 May 13; 100(10):6109-14. PMID: 12716975.
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    73. Hewison M, Kantorovich V, Liker HR, Van Herle AJ, Cohan P, Zehnder D, Adams JS. Vitamin D-mediated hypercalcemia in lymphoma: evidence for hormone production by tumor-adjacent macrophages. J Bone Miner Res. 2003 Mar; 18(3):579-82. PMID: 12619944.
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    74. Chen H, Hu B, Huang GH, Trainor AG, Abbott DH, Adams JS. Purification and characterization of a novel intracellular 17 beta-estradiol binding protein in estrogen-resistant New World primate cells. J Clin Endocrinol Metab. 2003 Jan; 88(1):501-4. PMID: 12519896.
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    75. Hill JA, Goldin JG, Gjertson D, Emerick AM, Greaser LD, Yoon HC, Khorrami S, Aziz D, Adams JS. Progression of coronary artery calcification in patients taking alendronate for osteoporosis. Acad Radiol. 2002 Oct; 9(10):1148-52. PMID: 12385509.
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    76. Wu S, Chun R, Gacad MA, Ren S, Chen H, Adams JS. Regulation of 1,25-dihydroxyvitamin d synthesis by intracellular vitamin d binding protein-1. Endocrinology. 2002 Oct; 143(10):4135. PMID: 12239126.
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    77. Kantorovich V, Adams JS, Gaines JE, Guo X, Pandian MR, Cohn DH, Rude RK. Genetic heterogeneity in familial renal magnesium wasting. J Clin Endocrinol Metab. 2002 Feb; 87(2):612-7. PMID: 11836293.
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    78. Adams JS, Gacad MA, Rude RK, Deseran M, Endres DB, Mallette LE. Immunoreactive parathyroid hormone levels in platyrrhini and catarrhini: A comparative analysis with three different assays. Am J Primatol. 1987; 13(4):425-433. PMID: 31973460.
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