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John S Adams

Title(s)Professor, Orthopaedic Surgery
SchoolMedicine
Phone75585, Adm 51394
ORCID ORCID Icon0000-0001-9607-5020 Additional info
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    Other Positions
    Title(s)Professor, Medicine


    Collapse Biography 
    Collapse Education and Training
    University of Kansas School of Medicine, Kansas City, KansasM.D.1974Medicine
    University of Kansas School of Medicine, Kansas City, KansasResidency1978Internal Medicine
    University of Kansas School of Medicine, Kansas City, KansasClinical Fellow1979Endocrinology
    Harvard University, Boston, MassachusettsPostdoctoral Felloiw1981Endocrinology
    Massachusetts General Hospital , Boston, MassachusettsInstructor1982Endocrinology
    Collapse Awards and Honors
    American Society for Bone and Mineral Research1983Young Investigator Award
    American Society for Clinical Investigation1990Elected Member
    Association of American Physicians2002Elected Member
    University of California2014Distinguished Professor
    American Society for Bone and Mineral Research2017Elected Fellow

    Collapse Overview 
    Collapse Overview
    Dr. Adams has been continually funded by the NIH for the last 40 years to do translational research in the field of vitamin D synthesis, metabolism and action. Adams’ current research portfolio includes: 1] the molecular biology of chromatin remodeling, transcription, splicing and miRNA action in response to sterol/steroid hormones; 2] the role of alternative splicing in determining stem cell fates in bone; 3] innate and adaptive molecular and cellular immunity with regard to vitamin D and its metabolites; 4] the translational aspects of human macrophage and neutrophil anti-microbial actions; 5] the impact of human vitamin D deficiency on innate immune-responsivity to microbes from orthopaedic implant infections and prosthetic wear debris; and 6] actions of vitamin D on the human musculoskeletal system in health and disease. He is the author of over 190 peer-reviewed publications in his field in the foremost scientific and biomedical research journals, including Nature, Science, Cell and the New England Journal of Medicine. Dr. Adams is an editor of the third edition of the signature text in his field, Vitamin D, and is on the editorial boards of the newest journals in his field, Bone Research and Journal of the Endocrine Society. He also serves on the consulting editorial board for the Journal of Clinical Investigation.

    Dr, Adams is i) founding and current Director of the UCLA-Orthopaedic Hospital Research Center, ii) Vice Chair for Research in the UCLA Department of Orthopaedic Surgery, iii) founding Principal Investigator of the NIAMS-funded Orthopaedic T32 at UCLA, iv) founding and current Associate Director of the UCLA Clinical and Translation Science Institute (CTSI; CTSA to UCLA), v) founding Director of the California Institute for Regenerative Medicine-funded UCLA Alpha Stem Cell Clinic, and vi) Assistant Dean for Translational Research. Collectively, these programs are designed to open up new transdisiplinary opportunities for precedent-setting research in the field of translational science for senior and junior investigators, particularly surgeon scientists during the formative stages of their independent research career.

    Dr. Adams has a long and successful track record in training undergraduate, graduate, postdoctoral and medical students as well as junior faculty for careers in research under the auspices of extramural funding from the NIH. In his laboratory and translational research program over the past ten years Dr. Adams has trained; i) 18 undergraduates (including three Hispanics and two African Americans), ten of whom have applied to or entered medical school and seven of whom have entered graduate school, ii) ten graduate students (including two Hispanics), all of whom have matriculated to post-doctoral fellowships or medical school, iii) ten postdoctoral fellows (including one Pacific Islander), nine of whom have taken jobs in academia or industry and iv) three medical students (including one Hispanic). During this same ten-year period Dr. Adams has served as mentor for eight junior faculty on NIH- and VA- supported career development awards..

    Collapse Research 
    Collapse Research Activities and Funding
    Impact of ethnicity in the gut microbiome in response to oral vitamin D replacement
    NIH/NIAMS R21AR073018Sep 18, 2017 - Aug 31, 2018
    Role: Principal Investigator
    UCLA/UCI Alpha Stem Cell Consoirtium
    California Institute for Regenerative Medicine AC1-07675-05Mar 1, 2015 - Dec 31, 2020
    Role: Principal Investigator
    Role Description: Develop the research infrastructure for first-in-man stem cell trials
    DBP and the bioavailability and function of vitamin D
    NIH/NIAMS R01AR063910Sep 1, 2013 - May 31, 2018
    Role: Principal Investigator
    Regenerative Musculoskeletal Medicine Training Program
    NIH/NIAMS T32AR059033Apr 1, 2010 - Jul 31, 2021
    Role: Principal Investigator
    Orthopaedic Wear Debris, Vitamin D, and Innate Immunity
    NIH/NIAMS R21AR056885Aug 1, 2009 - Jul 31, 2012
    Role: Principal Investigator
    CO-FACILITATORS: NOVEL REGULATORS OF HORMONE METABOLISM
    NIH/NIDDK R01DK058891Sep 1, 2001 - Aug 31, 2006
    Role: Principal Investigator
    BISPHOSPHONATES AND EXTRAOSSEOUS CALCIFICATION
    NIH/NIAMS R01AR046231Sep 30, 1999 - Aug 31, 2003
    Role: Principal Investigator
    Vitamin D and Estrogen Action in Bone: Concerted Role for hnRNPs in the C Family
    NIH/NIAMS R01AR037399Apr 1, 1988 - Mar 31, 1993
    Role: Principal Investigator
    VITAMIN D METABOLISM IN SARCOIDOSIS
    NIH/NIAID R01AI040403Jul 1, 1985 - Mar 31, 2002
    Role: Principal Investigator
    VITAMIN D METABOLISM IN SARCOIDOSIS AND LYMPHOMA
    NIH/NIDDK R01DK033139Jul 1, 1985 - Jun 30, 1995
    Role: Principal Investigator
    METABOLISM OF 25-HYDROXYVITAMIN D3 BY PAM IN SARCOIDOSIS
    NIH/NIADDK R23AM033139Jul 1, 1985 - Jun 30, 1988
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Preoperative Vitamin D Repletion in Total Knee Arthroplasty: A Cost-Effectiveness Model. J Arthroplasty. 2020 May; 35(5):1379-1383. Arshi A, Shieh A, Adams JS, Bernthal NM, Zeegen EN, Sassoon AA. PMID: 31983566.
      View in: PubMed   Mentions:    Fields:    
    2. Vitamin D Binding Protein and the Biological Activity of Vitamin D. Front Endocrinol (Lausanne). 2019; 10:718. Chun RF, Shieh A, Gottlieb C, Yacoubian V, Wang J, Hewison M, Adams JS. PMID: 31708871.
      View in: PubMed   Mentions:
    3. Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN. PLoS Negl Trop Dis. 2018 10; 12(10):e0006815. Zavala K, Gottlieb CA, Teles RM, Adams JS, Hewison M, Modlin RL, Liu PT. PMID: 30300363.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. CIRM Alpha Stem Cell Clinics: Collaboratively Addressing Regenerative Medicine Challenges. Cell Stem Cell. 2018 06 01; 22(6):801-805. Jamieson CHM, Millan MT, Creasey AA, Lomax G, Donohoe ME, Walters MC, Abedi M, Bota DA, Zaia JA, Adams JS. PMID: 29859170.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. Concerted effects of heterogeneous nuclear ribonucleoprotein C1/C2 to control vitamin D-directed gene transcription and RNA splicing in human bone cells. Nucleic Acids Res. 2017 01 25; 45(2):606-618. Zhou R, Park JW, Chun RF, Lisse TS, Garcia AJ, Zavala K, Sea JL, Lu ZX, Xu J, Adams JS, Xing Y, Hewison M. PMID: 27672039.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    6. Differential Responses to Vitamin D2 and Vitamin D3 Are Associated With Variations in Free 25-Hydroxyvitamin D. Endocrinology. 2016 09; 157(9):3420-30. Chun RF, Hernandez I, Pereira R, Swinkles L, Huijs T, Zhou R, Liu NQ, Shieh A, Guemes M, Mallya SM, Adams JS, Hewison M. PMID: 27399876.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    7. High throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 01; 1014:56-63. Jenkinson C, Taylor AE, Hassan-Smith ZK, Adams JS, Stewart PM, Hewison M, Keevil BG. PMID: 26874878.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    8. NELL-1 in the treatment of osteoporotic bone loss. Nat Commun. 2015 Jun 17; 6:7362. James AW, Shen J, Zhang X, Asatrian G, Goyal R, Kwak JH, Jiang L, Bengs B, Culiat CT, Turner AS, Seim Iii HB, Wu BM, Lyons K, Adams JS, Ting K, Soo C. PMID: 26082355.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    9. Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis. Osteoarthritis Cartilage. 2015 Feb; 23(2):308-18. Wu L, Petrigliano FA, Ba K, Lee S, Bogdanov J, McAllister DR, Adams JS, Rosenthal AK, Van Handel B, Crooks GM, Lin Y, Evseenko D. PMID: 25464168.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    10. Vitamin D and alternative splicing of RNA. J Steroid Biochem Mol Biol. 2015 Apr; 148:310-7. Zhou R, Chun RF, Lisse TS, Garcia AJ, Xu J, Adams JS, Hewison M. PMID: 25447737.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    11. Cloning of a functional 25-hydroxyvitamin D-1a-hydroxylase in zebrafish (Danio rerio). Cell Biochem Funct. 2014 Dec; 32(8):675-82. Chun RF, Blatter E, Elliott S, Fitz-Gibbon S, Rieger S, Sagasti A, Adams JS, Hewison M. PMID: 25290078.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    12. IL-32 is a molecular marker of a host defense network in human tuberculosis. Sci Transl Med. 2014 Aug 20; 6(250):250ra114. Montoya D, Inkeles MS, Liu PT, Realegeno S, Teles RM, Vaidya P, Munoz MA, Schenk M, Swindell WR, Chun R, Zavala K, Hewison M, Adams JS, Horvath S, Pellegrini M, Bloom BR, Modlin RL. PMID: 25143364.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    13. Vitamin D supplementation and antibacterial immune responses in adolescents and young adults with HIV/AIDS. J Steroid Biochem Mol Biol. 2015 Apr; 148:290-7. Chun RF, Liu NQ, Lee T, Schall JI, Denburg MR, Rutstein RM, Adams JS, Zemel BS, Stallings VA, Hewison M. PMID: 25092518.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    14. Vitamin D signaling regulates oral keratinocyte proliferation in vitro and in vivo. Int J Oncol. 2014 May; 44(5):1625-33. Yuan FN, Valiyaparambil J, Woods MC, Tran H, Pant R, Adams JS, Mallya SM. PMID: 24626468.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    15. The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1,25-dihydroxyvitamin D-directed transcriptional events in osteoblasts. Bone Res. 2014; 2. Lisse TS, Vadivel K, Bajaj SP, Chun RF, Hewison M, Adams JS. PMID: 25506471.
      View in: PubMed   Mentions:
    16. Regulation of the extrarenal CYP27B1-hydroxylase. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:22-7. Adams JS, Rafison B, Witzel S, Reyes RE, Shieh A, Chun R, Zavala K, Hewison M, Liu PT. PMID: 24388948.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    17. Vitamin D and DBP: the free hormone hypothesis revisited. J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A:132-7. Chun RF, Peercy BE, Orwoll ES, Nielson CM, Adams JS, Hewison M. PMID: 24095930.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansAnimals
    18. Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes. J Bone Miner Res. 2013 Jan; 28(1):46-55. Bacchetta J, Sea JL, Chun RF, Lisse TS, Wesseling-Perry K, Gales B, Adams JS, Salusky IB, Hewison M. PMID: 22886720.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    19. Redefining Human Vitamin D Sufficiency: Back to the Basics. Bone Res. 2013; 1(1):2-10. Adams JS, Ramin J, Rafison B, Windon C, Windon A, Liu PT. PMID: 25285234.
      View in: PubMed   Mentions:
    20. Extrarenal expression of the 25-hydroxyvitamin D-1-hydroxylase. Arch Biochem Biophys. 2012 Jul 01; 523(1):95-102. Adams JS, Hewison M. PMID: 22446158.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    21. The John Charnley Award: an accurate and extremely sensitive method to separate, display, and characterize wear debris: part 2: metal and ceramic particles. Clin Orthop Relat Res. 2012 Feb; 470(2):339-50. Billi F, Benya P, Kavanaugh A, Adams J, McKellop H, Ebramzadeh E. PMID: 21932105.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    22. The John Charnley Award: an accurate and sensitive method to separate, display, and characterize wear debris: part 1: polyethylene particles. Clin Orthop Relat Res. 2012 Feb; 470(2):329-38. Billi F, Benya P, Kavanaugh A, Adams J, Ebramzadeh E, McKellop H. PMID: 21997780.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    23. Vitamin D binding protein and monocyte response to 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D: analysis by mathematical modeling. PLoS One. 2012; 7(1):e30773. Chun RF, Peercy BE, Adams JS, Hewison M. PMID: 22292037.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    24. Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Sci Transl Med. 2011 Oct 12; 3(104):104ra102. Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, Hollis BW, Hewison M, Adams JS, Steinmeyer A, Zügel U, Cheng G, Jo EK, Bloom BR, Modlin RL. PMID: 21998409.
      View in: PubMed   Mentions: 178     Fields:    Translation:HumansCells
    25. Immunomodulation by vitamin D: implications for TB. Expert Rev Clin Pharmacol. 2011 Sep; 4(5):583-91. Chun RF, Adams JS, Hewison M. PMID: 22046197.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    26. Vitamin D in HIV-Infected Patients. Curr HIV/AIDS Rep. 2011 Sep; 8(3):133-41. Lake JE, Adams JS. PMID: 21647555.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    27. Cord blood vitamin D status impacts innate immune responses. J Clin Endocrinol Metab. 2011 Jun; 96(6):1835-43. Walker VP, Zhang X, Rastegar I, Liu PT, Hollis BW, Adams JS, Modlin RL. PMID: 21470993.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    28. Hormone response element binding proteins: novel regulators of vitamin D and estrogen signaling. Steroids. 2011 Mar; 76(4):331-9. Lisse TS, Hewison M, Adams JS. PMID: 21236284.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    29. Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats. J Bone Miner Res. 2010 Jun; 25(6):1337-49. Hokugo A, Christensen R, Chung EM, Sung EC, Felsenfeld AL, Sayre JW, Garrett N, Adams JS, Nishimura I. PMID: 20200938.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    30. Update in vitamin D. J Clin Endocrinol Metab. 2010 Feb; 95(2):471-8. Adams JS, Hewison M. PMID: 20133466.
      View in: PubMed   Mentions: 229     Fields:    Translation:HumansAnimals
    31. Vitamin D insufficiency and skeletal development in utero. J Bone Miner Res. 2010 Jan; 25(1):11-3. Hewison M, Adams JS. PMID: 20091930.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    32. Vitamin D-mediated hypercalcemia and Cushing syndrome as manifestations of malignant pleural mesothelioma. Endocr Pract. 2008 Nov; 14(8):1011-6. Lee JM, Pou K, Sadow PM, Chen H, Hu B, Hewison M, Adams JS, Sugarbaker DJ, Fisher ND. PMID: 19095601.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation. Endocrinology. 2008 Oct; 149(10):4799-808. Liu N, Nguyen L, Chun RF, Lagishetty V, Ren S, Wu S, Hollis B, DeLuca HF, Adams JS, Hewison M. PMID: 18535110.
      View in: PubMed   Mentions: 57     Fields:    Translation:Animals
    34. Back to the future: a new look at 'old' vitamin D. J Endocrinol. 2008 Aug; 198(2):261-9. Chun RF, Adams JS, Hewison M. PMID: 18495944.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    35. Vitamin D therapy. Curr Osteoporos Rep. 2008 Mar; 6(1):5-11. Geller JL, Adams JS. PMID: 18430394.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab. 2008 Feb; 4(2):80-90. Adams JS, Hewison M. PMID: 18212810.
      View in: PubMed   Mentions: 230     Fields:    Translation:Humans
    37. Substrate and enzyme trafficking as a means of regulating 1,25-dihydroxyvitamin D synthesis and action: the human innate immune response. J Bone Miner Res. 2007 Dec; 22 Suppl 2:V20-4. Adams JS, Chen H, Chun R, Ren S, Wu S, Gacad M, Nguyen L, Ride J, Liu P, Modlin R, Hewison M. PMID: 18290716.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    38. Cinacalcet in the management of tumor-induced osteomalacia. J Bone Miner Res. 2007 Jun; 22(6):931-7. Geller JL, Khosravi A, Kelly MH, Riminucci M, Adams JS, Collins MT. PMID: 17352646.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCTClinical Trials
    39. Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease. J Steroid Biochem Mol Biol. 2007 Mar; 103(3-5):316-21. Hewison M, Burke F, Evans KN, Lammas DA, Sansom DM, Liu P, Modlin RL, Adams JS. PMID: 17368179.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansCells
    40. Functional characterization of heterogeneous nuclear ribonuclear protein C1/C2 in vitamin D resistance: a novel response element-binding protein. J Biol Chem. 2006 Dec 22; 281(51):39114-20. Chen H, Hewison M, Adams JS. PMID: 17071612.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    41. 1,25-Dihydroxyvitamin D inhibits lipopolysaccharide-induced immune activation in human endothelial cells. Clin Exp Immunol. 2006 Jan; 143(1):58-64. Equils O, Naiki Y, Shapiro AM, Michelsen K, Lu D, Adams J, Jordan S. PMID: 16367934.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    42. "Bound" to work: the free hormone hypothesis revisited. Cell. 2005 Sep 09; 122(5):647-9. Adams JS. PMID: 16143095.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    43. Response element binding proteins and intracellular vitamin D binding proteins: novel regulators of vitamin D trafficking, action and metabolism. J Steroid Biochem Mol Biol. 2004 May; 89-90(1-5):461-5. Adams JS, Chen H, Chun R, Gacad MA, Encinas C, Ren S, Nguyen L, Wu S, Hewison M, Barsony J. PMID: 15225821.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsPHPublic Health
    44. An Hsp27-related, dominant-negative-acting intracellular estradiol-binding protein. J Biol Chem. 2004 Jul 16; 279(29):29944-51. Chen H, Hewison M, Hu B, Sharma M, Sun Z, Adams JS. PMID: 15123601.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    45. Novel regulators of vitamin D action and metabolism: Lessons learned at the Los Angeles zoo. J Cell Biochem. 2003 Feb 01; 88(2):308-14. Adams JS, Chen H, Chun RF, Nguyen L, Wu S, Ren SY, Barsony J, Gacad MA. PMID: 12520531.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    46. Purification and characterization of a novel intracellular 17 beta-estradiol binding protein in estrogen-resistant New World primate cells. J Clin Endocrinol Metab. 2003 Jan; 88(1):501-4. Chen H, Hu B, Huang GH, Trainor AG, Abbott DH, Adams JS. PMID: 12519896.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    47. Progression of coronary artery calcification in patients taking alendronate for osteoporosis. Acad Radiol. 2002 Oct; 9(10):1148-52. Hill JA, Goldin JG, Gjertson D, Emerick AM, Greaser LD, Yoon HC, Khorrami S, Aziz D, Adams JS. PMID: 12385509.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Regulation of 1,25-dihydroxyvitamin d synthesis by intracellular vitamin d binding protein-1. Endocrinology. 2002 Oct; 143(10):4135. Wu S, Chun R, Gacad MA, Ren S, Chen H, Adams JS. PMID: 12239126.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    49. Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging. Nat Med. 2002 Aug; 8(8):891-7. Adams JY, Johnson M, Sato M, Berger F, Gambhir SS, Carey M, Iruela-Arispe ML, Wu L. PMID: 12134144.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimals
    50. The vitamin D response element-binding protein. A novel dominant-negative regulator of vitamin D-directed transactivation. J Biol Chem. 2000 Nov 10; 275(45):35557-64. Chen H, Hu B, Allegretto EA, Adams JS. PMID: 10948206.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    51. Cloning and expression of a novel dominant-negative-acting estrogen response element-binding protein in the heterogeneous nuclear ribonucleoprotein family. J Biol Chem. 1998 Nov 20; 273(47):31352-7. Chen H, Hu B, Gacad MA, Adams JS. PMID: 9813044.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    52. Functional characterization and purification of an intracellular vitamin D-binding protein in vitamin D-resistant new world primate cells. Amino acid sequence homology with proteins in the hsp-70 family. J Biol Chem. 1997 Mar 28; 272(13):8433-40. Gacad MA, Chen H, Arbelle JE, LeBon T, Adams JS. PMID: 9079669.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    53. Autoregulation of 1,25-dihydroxyvitamin D synthesis in macrophage mitochondria by nitric oxide. Endocrinology. 1996 Oct; 137(10):4514-7. Adams JS, Ren SY. PMID: 8828516.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    54. A role for nitric oxide in the regulated expression of the 25-hydroxy-vitamin D-1-hydroxylation reaction in the chick myelomonocytic cell line HD-11. Endocrinology. 1994 Jan; 134(1):499-502. Adams JS, Ren SY, Arbelle JE, Clemens TL, Shany S. PMID: 8275965.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    55. Absence of thyroid hormone resistance in vitamin D-;resistant new world primates. Am J Primatol. 1994; 32(3):215-222. Arbelle JE, Gacad MA, Spencer CA, Adams JS. PMID: 31936922.
      View in: PubMed   Mentions:    Fields:    
    56. Influence of ultraviolet B radiation on vitamin D3 metabolism in vitamin D3-resistant New World primates. Am J Primatol. 1992; 28(4):263-270. Gacad MA, Deseran MW, Adams JS. PMID: 31941204.
      View in: PubMed   Mentions:    Fields:    
    57. Constitutive expression of a vitamin D 1-hydroxylase in a myelomonocytic cell line: a model for studying 1,25-dihydroxyvitamin D production in vitro. J Bone Miner Res. 1990 Dec; 5(12):1265-9. Adams JS, Beeker TG, Hongo T, Clemens TL. PMID: 1963733.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    58. Pharmacokinetics of calcitriol in continuous ambulatory and cycling peritoneal dialysis patients. Am J Kidney Dis. 1990 Aug; 16(2):126-32. Salusky IB, Goodman WG, Horst R, Segre GV, Kim L, Norris KC, Adams JS, Holloway M, Fine RN, Coburn JW. PMID: 2382648.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    59. Tumoral calcinosis-like lesion of the proximal linea aspera. Skeletal Radiol. 1990; 19(8):579-83. Seeger LL, Butler DL, Eckardt JJ, Layfield L, Adams JS. PMID: 2278012.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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