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William Louis Sheppard

Title(s)Assistant Professor-in-residence, Orthopaedic Surgery
SchoolMedicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Different Concepts in Short Segment Reconstruction of Moderate to Severe PI-LL Mismatch Deformity with ALIF, Mini-PSO, and TLIF: A Video Case Series. Clin Spine Surg. 2025 Jun 01; 38(5):230-237. Sheppard W, Reading L, Patel AA, Greenberg J, Spiessberger A. PMID: 40163631.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Glucagon-Like Peptide-1 Receptor Agonist Medications Alter Outcomes of Spine Surgery: A Study Among Over 15,000 Patients. Spine (Phila Pa 1976). 2025 Jul 01; 50(13):871-880. Wiener JM, Sanghvi PA, Vlastaris K, Mroz T, Belding J, Kaelber DC, Olson T, Francis KP, Adams JS, Bernthal N, Sheppard WL. PMID: 39895110.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Atlanto-occipital Dissociation: A Review on Epidemiology, Recognition and Diagnosis, Management Options, Outcomes, and Future Directions. Clin Spine Surg. 2024 Nov 01; 37(9):395-403. Sheppard WL, Savage JW, Moore T. PMID: 39356168.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Surgical Technique for TDR/ACDF Hybrid Constructs: A Surgical Video Case Example. World Neurosurg. 2024 11; 191:197. Sheppard W, Rudic T, Patel AA, Spiessberger A. PMID: 39179027.
      View in: PubMed   Mentions:    Fields:    
    5. Global utilization of biportal spinal endoscopy: Case series on management of lumbar pathology in Soddo, Ethiopia. Int J Surg Case Rep. 2024 Sep; 122:110046. Sheppard WL, Getachew K, Zelalem T, Anderson D, Park DY. PMID: 39047398; PMCID: PMC11320474.
      View in: PubMed   Mentions:
    6. Does the use of tranexamic acid intraoperatively reduce postoperative blood loss and complications following biportal endoscopic lumbosacral decompression? J Spine Surg. 2024 Mar 20; 10(1):68-79. Upfill-Brown A, Olson T, Adejuyigbe B, Shah A, Sheppard W, Park CW, Heo DH, Park DY. PMID: 38567010; PMCID: PMC10982914.
      View in: PubMed   Mentions: 1  
    7. Biportal Endoscopic Approach for Lumbar Degenerative Disease in the Ambulatory Outpatient vs Inpatient Setting: A Comparative Study. Int J Spine Surg. 2023 Dec 26; 17(6):858-865. Park DY, Olson TE, Upfill-Brown A, Adejuyigbe B, Shah AA, Sheppard WL, Park CW, Heo DH. PMID: 37770193; PMCID: PMC10753325.
      View in: PubMed   Mentions: 4  
    8. Spinal Cord Signal Intensity Predicts Functional Outcomes in the Operative Management of Degenerative Cervical Myelopathy. Clin Spine Surg. 2023 12 01; 36(10):438-443. Firempong GK, Sheppard WL, Gelfand Y, Ellingson BM, Holly LT. PMID: 38031316; PMCID: PMC10691530.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Clinical outcomes and complications after biportal endoscopic spine surgery: a comprehensive systematic review and meta-analysis of 3673 cases. Eur Spine J. 2023 08; 32(8):2637-2646. Park DY, Upfill-Brown A, Curtin N, Hamad CD, Shah A, Kwon B, Kim YH, Heo DH, Park CW, Sheppard WL. PMID: 37079079.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    10. Spondylolisthesis and mismatch deformity affect outcomes after total knee arthroplasty. J Orthop Surg Res. 2023 Mar 02; 18(1):157. Sheppard WL, Chiou D, Upfill-Brown A, Shah A, Edogun E, Sassoon A, Park DY. PMID: 36864440; PMCID: PMC9979472.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    11. Development and External Validation of a Risk Calculator for Prediction of Major Complications and Readmission After Anterior Cervical Discectomy and Fusion. Spine (Phila Pa 1976). 2023 Apr 01; 48(7):460-467. Shah AA, Devana SK, Lee C, Olson TE, Upfill-Brown A, Sheppard WL, Lord EL, Shamie AN, van der Schaar M, SooHoo NF, Park DY. PMID: 36730869; PMCID: PMC10023283.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    12. A Call to Action: Improving the Surgical Training Experience for Residents Underrepresented in Medicine. Ann Surg. 2023 02 01; 277(2):e254-e256. Liu TP, Wang A, Sheppard WL, Stavrakis AI, Hines OJ, McIntosh D. PMID: 36120865.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. National trends in the utilization of lumbar disc replacement for lumbar degenerative disc disease over a 10-year period, 2010 to 2019. J Spine Surg. 2022 Sep; 8(3):343-352. Upfill-Brown A, Policht J, Sperry BP, Ghosh D, Shah AA, Sheppard WL, Lord E, Shamie AN, Park DY. PMID: 36285102; PMCID: PMC9547699.
      View in: PubMed   Mentions: 5  
    14. Severity and location of lumbar spine stenosis affects the outcome of total knee arthroplasty. J Orthop Surg Res. 2021 Dec 20; 16(1):720. Sheppard WL, McKay KM, Upfill-Brown A, Blumstein G, Park HY, Shah A, Sassoon AA, Park DY. PMID: 34930340; PMCID: PMC8686657.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    15. Predictors of Medical Malpractice Outcomes After Spine Surgery: A Comprehensive Analysis From 2010 to 2019. Clin Spine Surg. 2021 07 01; 34(6):228-235. Park HY, Hwang R, Sheppard WL, Blumstein G, Shah AA, Medina JA, Cargle MN, Bugarin A, Hamad CD, Proal JD, Smith R, Bernthal NM, Shamie AN, Park DY. PMID: 33872221.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. Spinal Cord Drift Following Laminoplasty Versus Laminectomy and Fusion for Cervical Spondylotic Myelopathy. Int J Spine Surg. 2021 Apr; 15(2):205-212. Ashana AO, Ajiboye RM, Sheppard WL, Ishmael CR, Cohen JY, Beckett JS, Holly LT. PMID: 33900976; PMCID: PMC8059389.
      View in: PubMed   Mentions: 4  
    17. Updated external validation of the SORG machine learning algorithms for prediction of ninety-day and one-year mortality after surgery for spinal metastasis. Spine J. 2021 10; 21(10):1679-1686. Shah AA, Karhade AV, Park HY, Sheppard WL, Macyszyn LJ, Everson RG, Shamie AN, Park DY, Schwab JH, Hornicek FJ. PMID: 33798728.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    18. Intermittent and Transient Hypotension-related Anterior Cord Syndrome following Elective Cervical Spine Surgery: A Case Report. J Orthop Case Rep. 2021 Mar; 11(3):21-24. Greig D, Zoller S, Sheppard WL, Park DY. PMID: 34239823; PMCID: PMC8241245.
      View in: PubMed   Mentions:
    19. Lumbar Spine Sagittal Mismatch Deformity Negatively Affects Total Knee Arthroplasty Outcomes. J Knee Surg. 2022 Nov; 35(13):1409-1416. Sheppard WL, Upfill-Brown A, McKay KM, Park HY, Shah A, Park DY, Sassoon AA. PMID: 33618399.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    20. Comparison of two fluorescent probes in preclinical non-invasive imaging and image-guided debridement surgery of Staphylococcal biofilm implant infections. Sci Rep. 2021 01 15; 11(1):1622. Park HY, Zoller SD, Hegde V, Sheppard W, Burke Z, Blumstein G, Hamad C, Sprague M, Hoang J, Smith R, Romero Pastrana F, Czupryna J, Miller LS, López-Álvarez M, Bispo M, van Oosten M, van Dijl JM, Francis KP, Bernthal NM. PMID: 33452271; PMCID: PMC7810895.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    21. Evading the host response: Staphylococcus "hiding" in cortical bone canalicular system causes increased bacterial burden. Bone Res. 2020 Dec 10; 8(1):43. Zoller SD, Hegde V, Burke ZDC, Park HY, Ishmael CR, Blumstein GW, Sheppard W, Hamad C, Loftin AH, Johansen DO, Smith RA, Sprague MM, Hori KR, Clarkson SJ, Borthwell R, Simon SI, Miller JF, Nelson SD, Bernthal NM. PMID: 33303744; PMCID: PMC7728749.
      View in: PubMed   Mentions: 19     Fields:    
    22. Implications of sagittal alignment and complication profile with stand-alone anterior lumbar interbody fusion versus anterior posterior lumbar fusion. J Spine Surg. 2020 Dec; 6(4):659-669. Ahlquist S, Thommen R, Park HY, Sheppard W, James K, Lord E, Shamie AN, Park DY. PMID: 33447668; PMCID: PMC7797796.
      View in: PubMed   Mentions: 6  
    23. Delayed Diagnosis Is the Primary Cause of Sarcoma Litigation: Analysis of Malpractice Claims in the United States. Clin Orthop Relat Res. 2020 10; 478(10):2239-2253. Hwang R, Park HY, Sheppard W, Bernthal NM. PMID: 32496320; PMCID: PMC7491906.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    24. Novel in vivo mouse model of shoulder implant infection. J Shoulder Elbow Surg. 2020 Jul; 29(7):1412-1424. Sheppard WL, Mosich GM, Smith RA, Hamad CD, Park HY, Zoller SD, Trikha R, McCoy TK, Borthwell R, Hoang J, Truong N, Cevallos N, Clarkson S, Hori KR, van Dijl JM, Francis KP, Petrigliano FA, Bernthal NM. PMID: 32014357; PMCID: PMC11037115.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    25. Progress not panacea: vancomycin powder efficacy and dose evaluated in an in vivo mouse model of spine implant infection. Spine J. 2020 06; 20(6):973-980. Park HY, Hegde V, Zoller SD, Sheppard W, Hamad C, Smith RA, Sprague MM, Proal JD, Hoang J, Loftin A, Blumstein G, Burke Z, Cevallos N, Scaduto AA, Bernthal NM. PMID: 31863932; PMCID: PMC7351246.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    26. Accurate Reporting of Concomitant Procedures Is Highly Variable in Studies Investigating Knee Cartilage Restoration. Cartilage. 2021 07; 12(3):333-343. Sheppard WL, Hinckel BB, Arshi A, Sherman SL, Jones KJ. PMID: 30971096; PMCID: PMC8236649.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. Multimodal imaging guides surgical management in a preclinical spinal implant infection model. JCI Insight. 2019 Feb 07; 4(3). Zoller SD, Park HY, Olafsen T, Zamilpa C, Burke ZD, Blumstein G, Sheppard WL, Hamad CD, Hori KR, Tseng JC, Czupryna J, McMannus C, Lee JT, Bispo M, Romero Pastrana F, Raineri EJ, Miller JF, Miller LS, van Dijl JM, Francis KP, Bernthal NM. PMID: 30728332; PMCID: PMC6413782.
      View in: PubMed   Mentions: 11     Fields:    
    28. A Comparison of Defense and Plaintiff Expert Witnesses in Orthopaedic Surgery Malpractice Litigation. J Bone Joint Surg Am. 2018 Jun 06; 100(11):e78. Park HY, Zoller SD, Sheppard WL, Hegde V, Smith RA, Borthwell RM, Clarkson SJ, Hamad CD, Proal JD, Bernthal NM. PMID: 29870452; PMCID: PMC6636805.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. The combined administration of vancomycin IV, standard prophylactic antibiotics, and vancomycin powder in spinal instrumentation surgery: does the routine use affect infection rates and bacterial resistance? J Spine Surg. 2018 Jun; 4(2):173-179. Park HY, Sheppard W, Smith R, Xiao J, Gatto J, Bowen R, Scaduto A, Holly L, Lu D, McBride D, Shamie AN, Park DY. PMID: 30069504; PMCID: PMC6046309.
      View in: PubMed   Mentions: 5  
    30. Academic Influence and Its Relationship to Industry Payments in Orthopaedic Surgery. J Bone Joint Surg Am. 2018 May 02; 100(9):e59. Buerba RA, Sheppard WL, Herndon KE, Gajewski N, Patel AD, Leong NL, Bernthal NM, SooHoo NF. PMID: 29715232.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    31. Use of the subcutaneous lumbar spine (SLS) index as a predictor for surgical complications in lumbar spine surgery. Spine J. 2018 12; 18(12):2181-2186. Shaw K, Chen J, Sheppard W, Alazzeh M, Park H, Park DY, Shamie AN. PMID: 29709549.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. Articular Cartilage Lesion Characteristic Reporting Is Highly Variable in Clinical Outcomes Studies of the Knee. Cartilage. 2019 07; 10(3):299-304. Jones KJ, Sheppard WL, Arshi A, Hinckel BB, Sherman SL. PMID: 29405742; PMCID: PMC6585291.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    33. Cervical Paraspinal Muscle Atrophy Rates Following Laminoplasty and Laminectomy with Fusion for Cervical Spondylotic Myelopathy. World Neurosurg. 2017 Nov; 107:445-450. Ashana AO, Ajiboye RM, Sheppard WL, Sharma A, Kay AB, Holly LT. PMID: 28790004.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Utility of Intraoperative Neuromonitoring for Lumbar Pedicle Screw Placement Is Questionable: A Review of 9957 Cases. Spine (Phila Pa 1976). 2017 Jul 01; 42(13):1006-1010. Ajiboye RM, Zoller SD, D'Oro A, Burke ZD, Sheppard W, Wang C, Buser Z, Wang JC, Pourtaheri S. PMID: 27851660; PMCID: PMC5552371.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    35. Staged reconstruction of diaphyseal fractures with segmental defects: Surgical and patient-reported outcomes. Injury. 2017 Oct; 48(10):2248-2252. Zoller SD, Cao LA, Smith RA, Sheppard W, Lord EL, Hamad CD, Ghodasra JH, Lee C, Jeffcoat D. PMID: 28712488.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    36. Regression of Disc-Osteophyte Complexes Following Laminoplasty Versus Laminectomy with Fusion for Cervical Spondylotic Myelopathy. Int J Spine Surg. 2017; 11:17. Ajiboye RM, Zoller SD, Ashana AA, Sharma A, Sheppard W, Holly LT. PMID: 28765801; PMCID: PMC5537950.
      View in: PubMed   Mentions: 5  
    37. Current management of aneurysmal bone cysts. Curr Rev Musculoskelet Med. 2016 Dec; 9(4):435-444. Park HY, Yang SK, Sheppard WL, Hegde V, Zoller SD, Nelson SD, Federman N, Bernthal NM. PMID: 27778155; PMCID: PMC5127951.
      View in: PubMed   Mentions: 88  
    38. An Early Warning Score Predicts Risk of Death after In-hospital Cardiopulmonary Arrest in Surgical Patients. Am Surg. 2015 Oct; 81(10):916-21. Stark AP, Maciel RC, Sheppard W, Sacks G, Hines OJ. PMID: 26463280.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. The impact of intracranial pressure monitoring on mortality after severe traumatic brain injury. Am J Surg. 2015 Dec; 210(6):1082-6; discussion 1086-7. MacLaughlin BW, Plurad DS, Sheppard W, Bricker S, Bongard F, Neville A, Smith JA, Putnam B, Kim DY. PMID: 26482513.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    40. Extreme oxatriquinanes: structural characterization of α-oxyoxonium species with extraordinarily long carbon-oxygen bonds. J Am Chem Soc. 2013 Jun 05; 135(22):8173-6. Gunbas G, Sheppard WL, Fettinger JC, Olmstead MM, Mascal M. PMID: 23682676.
      View in: PubMed   Mentions: 1     Fields:    
    41. Extreme oxatriquinanes and a record C-O bond length. Nat Chem. 2012 Dec; 4(12):1018-23. Gunbas G, Hafezi N, Sheppard WL, Olmstead MM, Stoyanova IV, Tham FS, Meyer MP, Mascal M. PMID: 23174982.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
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