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Claudio Scafoglio

Title(s)Associate Adjunct Professor, Medicine
SchoolMedicine
ORCID ORCID Icon0000-0003-1188-8124 Additional info
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    Seconda Università degli Studi di Napoli, ItalyMD07/2002Molecular Pathology
    Seconda Università degli Studi di Napoli, ItalyPhD12/2006Oncology

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A novel murine carcinogen-induced model recapitulates the progression and heterogeneity of human lung adenocarcinoma. Lung Cancer. 2025 Aug; 206:108581. Pandey A, Gomez E, Soto A, Jr MA, Jaldu S, Quezada F, Dumitras C, Saggese P, Liu B, Fishbein GA, Belperio J, Dubinett SM, Scafoglio C. PMID: 40680437.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    2. Exploring the Role of SGLT2 Inhibitors in Cancer: Mechanisms of Action and Therapeutic Opportunities. Cancers (Basel). 2025 Jan 30; 17(3). Pandey A, Alcaraz M, Saggese P, Soto A, Gomez E, Jaldu S, Yanagawa J, Scafoglio C. PMID: 39941833; PMCID: PMC11815934.
      View in: PubMed   Mentions: 5  
    3. Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma. Cancer Res. 2024 01 16; 84(2):305-327. Saggese P, Pandey A, Alcaraz M, Fung E, Hall A, Yanagawa J, Rodriguez EF, Grogan TR, Giurato G, Nassa G, Salvati A, Shirihai OS, Weisz A, Dubinett SM, Scafoglio C. PMID: 37934116; PMCID: PMC10790128.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    4. Glucose deprivation promotes pseudo-hypoxia and de-differentiation in lung adenocarcinoma. bioRxiv. 2023 Feb 01. Saggese P, Pandey A, Fung E, Hall A, Yanagawa J, Rodriguez EF, Grogan TR, Giurato G, Nassa G, Salvati A, Weisz A, Dubinett SM, Scafoglio C. PMID: 36778362; PMCID: PMC9915520.
      View in: PubMed   Mentions:
    5. Mitoquinone mesylate targets SARS-CoV-2 infection in preclinical models. bioRxiv. 2022 Jun 23. Petcherski A, Sharma M, Daskou M, Satta S, Vasilopoulos H, Hugo C, Ritou E, Dillon BJ, Fung E, Garcia G, Scafoglio C, Purkayastha A, Gomperts BN, Fishbein GA, Arumugaswami V, Liesa M, Shirihai OS, Kelesidis T. PMID: 35233569; PMCID: PMC8887067.
      View in: PubMed   Mentions: 1  
    6. Genotoxic Treatment Enhances Immune Response in a Genetic Model of Lung Cancer. Cancers (Basel). 2021 Jul 18; 13(14). Saggese P, Martinez CA, Tran LM, Lim R, Dumitras C, Grogan T, Elashoff D, Ramin SR, Dubinett SM, Liu B, Scafoglio C. PMID: 34298808; PMCID: PMC8307650.
      View in: PubMed   Mentions: 4  
    7. Regulation of Metabolic Reprogramming by Long Non-Coding RNAs in Cancer. Cancers (Basel). 2021 Jul 12; 13(14). Sellitto A, Pecoraro G, Giurato G, Nassa G, Rizzo F, Saggese P, Martinez CA, Scafoglio C, Tarallo R. PMID: 34298698; PMCID: PMC8308086.
      View in: PubMed   Mentions: 13  
    8. Metabolic Regulation of Epigenetic Modifications and Cell Differentiation in Cancer. Cancers (Basel). 2020 Dec 16; 12(12). Saggese P, Sellitto A, Martinez CA, Giurato G, Nassa G, Rizzo F, Tarallo R, Scafoglio C. PMID: 33339101; PMCID: PMC7765496.
      View in: PubMed   Mentions: 20  
    9. Heterogeneity of Glucose Transport in Lung Cancer. Biomolecules. 2020 06 05; 10(6). Martinez CA, Scafoglio C. PMID: 32517099; PMCID: PMC7356687.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    10. Does 2-FDG PET Accurately Reflect Quantitative In Vivo Glucose Utilization? J Nucl Med. 2020 06; 61(6):931-937. Barrio JR, Huang SC, Satyamurthy N, Scafoglio CS, Yu AS, Alavi A, Krohn KA. PMID: 31676728; PMCID: PMC7818046.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    11. p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas. Cell Rep. 2019 08 13; 28(7):1860-1878.e9. Hsieh MH, Choe JH, Gadhvi J, Kim YJ, Arguez MA, Palmer M, Gerold H, Nowak C, Do H, Mazambani S, Knighton JK, Cha M, Goodwin J, Kang MK, Jeong JY, Lee SY, Faubert B, Xuan Z, Abel ED, Scafoglio C, Shackelford DB, Minna JD, Singh PK, Shulaev V, Bleris L, Hoyt K, Kim J, Inoue M, DeBerardinis RJ, Kim TH, Kim JW. PMID: 31412252; PMCID: PMC7048935.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    12. Sodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma. Sci Transl Med. 2018 11 14; 10(467). Scafoglio CR, Villegas B, Abdelhady G, Bailey ST, Liu J, Shirali AS, Wallace WD, Magyar CE, Grogan TR, Elashoff D, Walser T, Yanagawa J, Aberle DR, Barrio JR, Dubinett SM, Shackelford DB. PMID: 30429355; PMCID: PMC6428683.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimals
    13. Positron emission tomography of sodium glucose cotransport activity in high grade astrocytomas. J Neurooncol. 2018 Jul; 138(3):557-569. Kepe V, Scafoglio C, Liu J, Yong WH, Bergsneider M, Huang SC, Barrio JR, Wright EM. PMID: 29525972; PMCID: PMC5999166.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    14. Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule. J Am Soc Nephrol. 2017 Mar; 28(3):802-810. Ghezzi C, Yu AS, Hirayama BA, Kepe V, Liu J, Scafoglio C, Powell DR, Huang SC, Satyamurthy N, Barrio JR, Wright EM. PMID: 27620988; PMCID: PMC5328165.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    15. Functional expression of sodium-glucose transporters in cancer. Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):E4111-9. Scafoglio C, Hirayama BA, Kepe V, Liu J, Ghezzi C, Satyamurthy N, Moatamed NA, Huang J, Koepsell H, Barrio JR, Wright EM. PMID: 26170283; PMCID: PMC4522748.
      View in: PubMed   Mentions: 169     Fields:    Translation:HumansAnimals
    16. Estrogen receptor beta impacts hormone-induced alternative mRNA splicing in breast cancer cells. BMC Genomics. 2015 May 09; 16:367. Dago DN, Scafoglio C, Rinaldi A, Memoli D, Giurato G, Nassa G, Ravo M, Rizzo F, Tarallo R, Weisz A. PMID: 25956916; PMCID: PMC4424892.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    17. The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation. PLoS One. 2013; 8(5):e59986. Scafoglio C, Smolka M, Zhou H, Perissi V, Rosenfeld MG. PMID: 23690919; PMCID: PMC3656868.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    18. TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints. Mol Cell. 2008 Mar 28; 29(6):755-66. Perissi V, Scafoglio C, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. PMID: 18374649; PMCID: PMC2364611.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    19. Influence of estrogens and antiestrogens on the expression of selected hormone-responsive genes. Maturitas. 2007 May 20; 57(1):50-5. Sismondi P, Biglia N, Ponzone R, Fuso L, Scafoglio C, Cicatiello L, Ravo M, Weisz A, Cimino D, Altobelli G, Friard O, De Bortoli M. PMID: 17395409.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    20. Comparative gene expression profiling reveals partially overlapping but distinct genomic actions of different antiestrogens in human breast cancer cells. J Cell Biochem. 2006 Aug 01; 98(5):1163-84. Scafoglio C, Ambrosino C, Cicatiello L, Altucci L, Ardovino M, Bontempo P, Medici N, Molinari AM, Nebbioso A, Facchiano A, Calogero RA, Elkon R, Menini N, Ponzone R, Biglia N, Sismondi P, De Bortoli M, Weisz A. PMID: 16514628.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    21. Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell. 2006 May 05; 125(3):593-605. Olson LE, Tollkuhn J, Scafoglio C, Krones A, Zhang J, Ohgi KA, Wu W, Taketo MM, Kemler R, Grosschedl R, Rose D, Li X, Rosenfeld MG. PMID: 16678101.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansAnimalsCells
    22. Molecular identification of ERalpha-positive breast cancer cells by the expression profile of an intrinsic set of estrogen regulated genes. J Cell Physiol. 2004 Sep; 200(3):440-50. Weisz A, Basile W, Scafoglio C, Altucci L, Bresciani F, Facchiano A, Sismondi P, Cicatiello L, De Bortoli M. PMID: 15254972.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    23. Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (progesterone receptor) complex assembly to a distal regulatory element and recruitment of cyclin D1 to its own gene promoter. Mol Cell Biol. 2004 Aug; 24(16):7260-74. Cicatiello L, Addeo R, Sasso A, Altucci L, Petrizzi VB, Borgo R, Cancemi M, Caporali S, Caristi S, Scafoglio C, Teti D, Bresciani F, Perillo B, Weisz A. PMID: 15282324; PMCID: PMC479712.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    24. A genomic view of estrogen actions in human breast cancer cells by expression profiling of the hormone-responsive transcriptome. J Mol Endocrinol. 2004 Jun; 32(3):719-75. Cicatiello L, Scafoglio C, Altucci L, Cancemi M, Natoli G, Facchiano A, Iazzetti G, Calogero R, Biglia N, De Bortoli M, Sfiligoi C, Sismondi P, Bresciani F, Weisz A. PMID: 15171711.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    25. Quantitative real-time RT-PCR analysis of eight novel estrogen-regulated genes in breast cancer. Int J Biol Markers. 2003 Apr-Jun; 18(2):123-9. Sorbello V, Fuso L, Sfiligoi C, Scafoglio C, Ponzone R, Biglia N, Weisz A, Sismondi P, De Bortoli M. PMID: 12841681.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
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