Claudio Scafoglio

Title(s)Associate Adjunct Professor, Medicine
SchoolMedicine
ORCID ORCID Icon0000-0003-1188-8124 Additional info
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    Seconda Università degli Studi di Napoli, ItalyMD07/2002Molecular Pathology
    Seconda Università degli Studi di Napoli, ItalyPhD12/2006Oncology

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Exploring the Role of SGLT2 Inhibitors in Cancer: Mechanisms of Action and Therapeutic Opportunities. Cancers (Basel). 2025 Jan 30; 17(3). Pandey A, Alcaraz M, Saggese P, Soto A, Gomez E, Jaldu S, Yanagawa J, Scafoglio C. PMID: 39941833; PMCID: PMC11815934.
      View in: PubMed   Mentions:
    2. Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma. Cancer Res. 2024 01 16; 84(2):305-327. Saggese P, Pandey A, Alcaraz M, Fung E, Hall A, Yanagawa J, Rodriguez EF, Grogan TR, Giurato G, Nassa G, Salvati A, Shirihai OS, Weisz A, Dubinett SM, Scafoglio C. PMID: 37934116; PMCID: PMC10790128.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    3. Glucose deprivation promotes pseudo-hypoxia and de-differentiation in lung adenocarcinoma. bioRxiv. 2023 Feb 01. Saggese P, Pandey A, Fung E, Hall A, Yanagawa J, Rodriguez EF, Grogan TR, Giurato G, Nassa G, Salvati A, Weisz A, Dubinett SM, Scafoglio C. PMID: 36778362; PMCID: PMC9915520.
      View in: PubMed   Mentions:
    4. Genotoxic Treatment Enhances Immune Response in a Genetic Model of Lung Cancer. Cancers (Basel). 2021 Jul 18; 13(14). Saggese P, Martinez CA, Tran LM, Lim R, Dumitras C, Grogan T, Elashoff D, Ramin SR, Dubinett SM, Liu B, Scafoglio C. PMID: 34298808; PMCID: PMC8307650.
      View in: PubMed   Mentions: 2  
    5. Metabolic Regulation of Epigenetic Modifications and Cell Differentiation in Cancer. Cancers (Basel). 2020 Dec 16; 12(12). Saggese P, Sellitto A, Martinez CA, Giurato G, Nassa G, Rizzo F, Tarallo R, Scafoglio C. PMID: 33339101; PMCID: PMC7765496.
      View in: PubMed   Mentions: 17  
    6. Heterogeneity of Glucose Transport in Lung Cancer. Biomolecules. 2020 06 05; 10(6). Martinez CA, Scafoglio C. PMID: 32517099; PMCID: PMC7356687.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    7. Does 2-FDG PET Accurately Reflect Quantitative In Vivo Glucose Utilization? J Nucl Med. 2020 06; 61(6):931-937. Barrio JR, Huang SC, Satyamurthy N, Scafoglio CS, Yu AS, Alavi A, Krohn KA. PMID: 31676728; PMCID: PMC7818046.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    8. p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas. Cell Rep. 2019 08 13; 28(7):1860-1878.e9. Hsieh MH, Choe JH, Gadhvi J, Kim YJ, Arguez MA, Palmer M, Gerold H, Nowak C, Do H, Mazambani S, Knighton JK, Cha M, Goodwin J, Kang MK, Jeong JY, Lee SY, Faubert B, Xuan Z, Abel ED, Scafoglio C, Shackelford DB, Minna JD, Singh PK, Shulaev V, Bleris L, Hoyt K, Kim J, Inoue M, DeBerardinis RJ, Kim TH, Kim JW. PMID: 31412252; PMCID: PMC7048935.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    9. Sodium-glucose transporter 2 is a diagnostic and therapeutic target for early-stage lung adenocarcinoma. Sci Transl Med. 2018 11 14; 10(467). Scafoglio CR, Villegas B, Abdelhady G, Bailey ST, Liu J, Shirali AS, Wallace WD, Magyar CE, Grogan TR, Elashoff D, Walser T, Yanagawa J, Aberle DR, Barrio JR, Dubinett SM, Shackelford DB. PMID: 30429355; PMCID: PMC6428683.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimals
    10. Positron emission tomography of sodium glucose cotransport activity in high grade astrocytomas. J Neurooncol. 2018 Jul; 138(3):557-569. Kepe V, Scafoglio C, Liu J, Yong WH, Bergsneider M, Huang SC, Barrio JR, Wright EM. PMID: 29525972; PMCID: PMC5999166.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    11. Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule. J Am Soc Nephrol. 2017 Mar; 28(3):802-810. Ghezzi C, Yu AS, Hirayama BA, Kepe V, Liu J, Scafoglio C, Powell DR, Huang SC, Satyamurthy N, Barrio JR, Wright EM. PMID: 27620988; PMCID: PMC5328165.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    12. Functional expression of sodium-glucose transporters in cancer. Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):E4111-9. Scafoglio C, Hirayama BA, Kepe V, Liu J, Ghezzi C, Satyamurthy N, Moatamed NA, Huang J, Koepsell H, Barrio JR, Wright EM. PMID: 26170283; PMCID: PMC4522748.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansAnimals
    13. The co-repressor SMRT delays DNA damage-induced caspase activation by repressing pro-apoptotic genes and modulating the dynamics of checkpoint kinase 2 activation. PLoS One. 2013; 8(5):e59986. Scafoglio C, Smolka M, Zhou H, Perissi V, Rosenfeld MG. PMID: 23690919; PMCID: PMC3656868.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    14. TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints. Mol Cell. 2008 Mar 28; 29(6):755-66. Perissi V, Scafoglio C, Zhang J, Ohgi KA, Rose DW, Glass CK, Rosenfeld MG. PMID: 18374649; PMCID: PMC2364611.
      View in: PubMed   Mentions: 80     Fields:    
    15. Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell. 2006 May 05; 125(3):593-605. Olson LE, Tollkuhn J, Scafoglio C, Krones A, Zhang J, Ohgi KA, Wu W, Taketo MM, Kemler R, Grosschedl R, Rose D, Li X, Rosenfeld MG. PMID: 16678101.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
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