Negar Khanlou

Title(s)	HS Clinical Professor, Pathology and Laboratory Medicine
School	Medicine
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Cellular Modeling of CLN6 with IPSC-derived Neurons and Glia. bioRxiv. 2024 Jan 30. Otero MG, Kim J, Kushwaha YK, Rajewski A, Nonis FD, Santiskulvong C, Bannykh SI, Oza H, Farooqi HMU, Babros M, Freeman C, Dupuis L, Mercimek-Andrews S, Mendoza-Londono R, Bresee C, Adams DR, Tifft CJ, Toro C, Khanlou N, Gahl WA, Salamon N, Pierson TM. PMID: 38352418; PMCID: PMC10862716.

View in: PubMed Mentions:
Enhancing mitosis quantification and detection in meningiomas with computational digital pathology. Acta Neuropathol Commun. 2024 Jan 11; 12(1):7. Gu H, Yang C, Al-Kharouf I, Magaki S, Lakis N, Williams CK, Alrosan SM, Onstott EK, Yan W, Khanlou N, Cobos I, Zhang XR, Zarrin-Khameh N, Vinters HV, Chen XA, Haeri M. PMID: 38212848; PMCID: PMC10782692.

View in: PubMed Mentions: Fields:
Neu Neurology
Translation:Humans
Small pretreatment lesion size and high sphericity as favorable prognostic factors after laser interstitial thermal therapy in brain metastases. J Neurosurg. 2024 Feb 01; 140(2):338-349. Sanvito F, Telesca D, Cho NS, Sayari JT, Nagaraj R, Raymond C, Rana S, Patel K, Mozaffari K, Unterberger AA, Khanlou N, Magaki S, Pouratian N, Everson RG, Yang I, Kim W, Ellingson BM. PMID: 37542437.

View in: PubMed Mentions: Fields:
Neu Neurosurgery
Translation:Humans
Whole-Exome Sequencing Identifies Homozygote Nonsense Variants in LMOD2 Gene Causing Infantile Dilated Cardiomyopathy. Cells. 2023 05 23; 12(11). Sono R, Larrinaga TM, Huang A, Makhlouf F, Kang X, Su J, Lau R, Arboleda VA, Biniwale R, Fishbein GA, Khanlou N, Si MS, Satou GM, Halnon N, Van Arsdell GS, Gregorio CC, Nelson S, Touma M. PMID: 37296576; PMCID: PMC10252268.

View in: PubMed Mentions: 1 Fields:
Bio Biophysics Cel Cell Biology Mol Molecular Biology
Translation:Humans
Hyaline protoplasmic astrocytopathy in epilepsy. Neuropathology. 2023 Dec; 43(6):441-456. Magaki S, Haeri M, Szymanski LJ, Chen Z, Diaz R, Williams CK, Chang JW, Ao Y, Newell KL, Khanlou N, Yong WH, Fallah A, Salamon N, Daniel T, Cotter J, Hawes D, Sofroniew M, Vinters HV. PMID: 37198977.

View in: PubMed Mentions: Fields:
Neu Neurology Pat Pathology
Translation:Humans Cells
A single-institution retrospective analysis of pathologically determined malignant transformation in IDH mutant glioma patients. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad036. Liu V, Wetzel EA, Eldred BSC, Zapanta Rinonos S, Prins TJ, Khanlou N, Liau LM, Chong R, Nghiemphu PL, Cloughesy TF, Ellingson BM, Lai A. PMID: 37152809; PMCID: PMC10162112.

View in: PubMed Mentions:
Neuropathology of microbleeds in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). J Neuropathol Exp Neurol. 2023 03 20; 82(4):333-344. Magaki S, Chen Z, Severance A, Williams CK, Diaz R, Fang C, Khanlou N, Yong WH, Paganini-Hill A, Kalaria RN, Vinters HV, Fisher M. PMID: 36715085; PMCID: PMC10025882.

View in: PubMed Mentions: 1 Fields:
Neu Neurology Pat Pathology
Translation:Humans
Retrospective examination of pseudoprogression in IDH mutant gliomas. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad028. Wetzel EA, Farrell MJ, Eldred BSC, Liu V, Saha I, Zapanta Rinonos S, Prins T, Li T, Cao M, Hegde J, Kaprealian T, Khanlou N, Liau LM, Nghiemphu PL, Cloughesy TF, Chong RA, Ellingson BM, Lai A. PMID: 37128507; PMCID: PMC10148681.

View in: PubMed Mentions:
Myofibrillar myopathy presenting with an inclusion body myositis-like phenotype. Muscle Nerve. 2023 05; 67(5):E15-E17. Diaz F, Soltanzadeh P, Khosa S, Khanlou N, Freundlich R, Mishra SK. PMID: 36815757.

View in: PubMed Mentions: Fields:
Neu Neurology Phy Physiology
Translation:Humans
Targeting chromosome 12q amplification in relapsed glioblastoma: the use of computational biological modeling to identify effective therapy-a case report. Ann Transl Med. 2022 Dec; 10(23):1289. Castro MP, Khanlou N, Fallah A, Pampana A, Alam A, Lala DA, Roy KGG, Amara ARR, Prakash A, Singh D, Behura L, Kumar A, Kapoor S. PMID: 36618786; PMCID: PMC9816820.

View in: PubMed Mentions: 1
Neuropathologic Findings in Elderly HIV-Positive Individuals. J Neuropathol Exp Neurol. 2022 06 20; 81(7):565-576. Magaki SD, Vinters HV, Williams CK, Mareninov S, Khanlou N, Said J, Nemanim N, Gonzalez J, Morales JG, Singer EJ, Yong WH. PMID: 35656871; PMCID: PMC9425852.

View in: PubMed Mentions: 1 Fields:
Neu Neurology Pat Pathology
Translation:Humans Cells
Solitary Extramedullary Plasmacytoma of the Lacrimal Sac With Associated Crystal-Storing Histiocytosis. Ophthalmic Plast Reconstr Surg. 2022 Mar-Apr 01; 38(2):102-107. Lee CM, Asilnejad B, Cohen LM, Roelofs KA, Rootman DB, Khanlou N, Pullarkat ST. PMID: 34406151.

View in: PubMed Mentions: 1 Fields:
Gen General Surgery Oph Ophthalmology
Translation:Humans Cells
Case Report: Whole Exome Sequencing Identifies Compound Heterozygous Variants in TSFM Gene Causing Juvenile Hypertrophic Cardiomyopathy. Front Cardiovasc Med. 2021; 8:798985. Yang JO, Shaybekyan H, Zhao Y, Kang X, Fishbein GA, Khanlou N, Alejos JC, Halnon N, Satou G, Biniwale R, Lee H, Van Arsdell G, Nelson SF, Touma M, UCLA Clinical Genomics Center, UCLA Congenital Heart Defects-BioCore Faculty. PMID: 35071363; PMCID: PMC8770926.

View in: PubMed Mentions: 1
Recessive ciliopathy mutations in primary endocardial fibroelastosis: a rare neonatal cardiomyopathy in a case of Alstrom syndrome. J Mol Med (Berl). 2021 11; 99(11):1623-1638. Zhao Y, Wang LK, Eskin A, Kang X, Fajardo VM, Mehta Z, Pineles S, Schmidt RJ, Nagiel A, Satou G, Garg M, Federman M, Reardon LC, Lee SL, Biniwale R, Grody WW, Halnon N, Khanlou N, Quintero-Rivera F, Alejos JC, Nakano A, Fishbein GA, Van Arsdell GS, Nelson SF, Touma M. PMID: 34387706; PMCID: PMC8541947.

View in: PubMed Mentions: 3 Fields:
Gen Genetics Mol Molecular Biology
Translation:Humans Cells
Charcot-Bouchard aneurysms revisited: clinicopathologic correlations. Mod Pathol. 2021 12; 34(12):2109-2121. Magaki S, Chen Z, Haeri M, Williams CK, Khanlou N, Yong WH, Vinters HV. PMID: 34326486; PMCID: PMC8592842.

View in: PubMed Mentions: 3 Fields:
Pat Pathology
Translation:Humans
Occult Colonic Perforation in a Patient With Coronavirus Disease 2019 After Interleukin-6 Receptor Antagonist Therapy. Open Forum Infect Dis. 2020 Nov; 7(11):ofaa424. Schwab K, Hamidi S, Chung A, Lim RJ, Khanlou N, Hoesterey D, Dumitras C, Adeyiga OB, Phan-Tang M, Wang TS, Saggar R, Goldstein J, Belperio JA, Dubinett SM, Kim JT, Salehi-Rad R. PMID: 33204749; PMCID: PMC7543619.

View in: PubMed Mentions: 3
Myopathy associated with homozygous PYROXD1 pathogenic variants detected by genome sequencing. Neuropathology. 2020 Jun; 40(3):302-307. Woods JD, Khanlou N, Lee H, Signer R, Shieh P, Chen J, Herzog M, Palmer C, Martinez-Agosto J, Undiagnosed Diseases Network, Nelson SF. PMID: 32037607; PMCID: PMC7317439.

View in: PubMed Mentions: 2 Fields:
Neu Neurology Pat Pathology
Translation:Humans
Large in-frame 5' deletions in DMD associated with mild Duchenne muscular dystrophy: Two case reports and a review of the literature. Neuromuscul Disord. 2019 11; 29(11):863-873. Gibbs EM, Barthélémy F, Douine ED, Hardiman NC, Shieh PB, Khanlou N, Crosbie RH, Nelson SF, Miceli MC. PMID: 31672265; PMCID: PMC7092699.

View in: PubMed Mentions: 3 Fields:
Neu Neurology
Translation:Humans Cells
Vertical asymmetric mitochondrial ophthalmoplegia. Can J Ophthalmol. 2019 10; 54(5):e230-e232. Pineles SL, Lewis RA, Khanlou N, Velez FG. PMID: 31564362.

View in: PubMed Mentions: Fields:
Oph Ophthalmology
Translation:Humans
A 44-year-old female with familial Mediterranean fever, cardiomyopathy and end stage renal disease. Brain Pathol. 2019 03; 29(2):312. Magaki S, Parks R, Vinters HV, Khanlou N. PMID: 30821026; PMCID: PMC8028615.

View in: PubMed Mentions: Fields:
Bra Brain Pat Pathology
Translation:Humans
Sample Preparation for Transmission Electron Microscopy. Methods Mol Biol. 2019; 1897:417-424. Tizro P, Choi C, Khanlou N. PMID: 30539461.

View in: PubMed Mentions: 19 Fields:
Mol Molecular Biology
Translation:Humans Cells
A Case of Tuberculosis-related Leukocytoclastic Vasculitis Presenting With Peripheral Neuropathy. Cureus. 2018 Dec 07; 10(12):e3703. Rafiei N, Khanlou N, Khosa S, Moheb N, Mishra SK. PMID: 30788192; PMCID: PMC6372249.

View in: PubMed Mentions: 1
Hydroxychloroquine-induced autophagic vacuolar myopathy with mitochondrial abnormalities. Neuropathology. 2018 Dec; 38(6):646-652. Khosa S, Khanlou N, Khosa GS, Mishra SK. PMID: 30411412.

View in: PubMed Mentions: 14 Fields:
Neu Neurology Pat Pathology
Translation:Humans Cells
DMD genotype correlations from the Duchenne Registry: Endogenous exon skipping is a factor in prolonged ambulation for individuals with a defined mutation subtype. Hum Mutat. 2018 09; 39(9):1193-1202. Wang RT, Barthelemy F, Martin AS, Douine ED, Eskin A, Lucas A, Lavigne J, Peay H, Khanlou N, Sweeney L, Cantor RM, Miceli MC, Nelson SF. PMID: 29907980; PMCID: PMC6175390.

View in: PubMed Mentions: 45 Fields:
Gen Genetics
Translation:Humans Cells
The effects of cerebral amyloid angiopathy on integrity of the blood-brain barrier. Neurobiol Aging. 2018 10; 70:70-77. Magaki S, Tang Z, Tung S, Williams CK, Lo D, Yong WH, Khanlou N, Vinters HV. PMID: 30007166; PMCID: PMC6146962.

View in: PubMed Mentions: 36 Fields:
Ger Geriatrics Neu Neurology Phy Physiology
Translation:Humans
A 44-Year-Old Female with Familial Mediterranean Fever, Cardiomyopathy and End Stage Renal Disease. Brain Pathol. 2018 01; 28(1):135-136. Magaki S, Parks R, Vinters HV, Khanlou N. PMID: 29265632; PMCID: PMC6130257.

View in: PubMed Mentions: 2 Fields:
Bra Brain Pat Pathology
Translation:Humans
Inflammation, oxidative stress, and glial cell activation characterize stellate ganglia from humans with electrical storm. JCI Insight. 2017 09 21; 2(18). Ajijola OA, Hoover DB, Simerly TM, Brown TC, Yanagawa J, Biniwale RM, Lee JM, Sadeghi A, Khanlou N, Ardell JL, Shivkumar K. PMID: 28931760; PMCID: PMC5621921.

View in: PubMed Mentions: 35 Fields:
Med Medicine (General)
Translation:Humans Cells
Early experience with formalin-fixed paraffin-embedded (FFPE) based commercial clinical genomic profiling of gliomas-robust and informative with caveats. Exp Mol Pathol. 2017 08; 103(1):87-93. Movassaghi M, Shabihkhani M, Hojat SA, Williams RR, Chung LK, Im K, Lucey GM, Wei B, Mareninov S, Wang MW, Ng DW, Tashjian RS, Magaki S, Perez-Rosendahl M, Yang I, Khanlou N, Vinters HV, Liau LM, Nghiemphu PL, Lai A, Cloughesy TF, Yong WH. PMID: 28663030.

View in: PubMed Mentions: 4 Fields:
Mol Molecular Biology Pat Pathology
Translation:Humans
61-year-old man with chronic expansile sellar mass. Brain Pathol. 2017 05; 27(3):397-398. Khanlou N, Tashjian R, Shahinian HK, Vinters HV. PMID: 28414887; PMCID: PMC8028862.

View in: PubMed Mentions: Fields:
Bra Brain Pat Pathology
Translation:Humans
Cardiac Transplantation in Dermatomyositis: A case report and literature review. Hum Pathol (N Y). 2017 Jun; 8:55-58. Bae S, Khanlou N, Charles-Schoeman C. PMID: 29204355; PMCID: PMC5710758.

View in: PubMed Mentions: 3
Incidence, survival, pathology, and genetics of adult Latino Americans with glioblastoma. J Neurooncol. 2017 04; 132(2):351-358. Shabihkhani M, Telesca D, Movassaghi M, Naeini YB, Naeini KM, Hojat SA, Gupta D, Lucey GM, Ontiveros M, Wang MW, Hanna LS, Sanchez DE, Mareninov S, Khanlou N, Vinters HV, Bergsneider M, Nghiemphu PL, Lai A, Liau LM, Cloughesy TF, Yong WH. PMID: 28161760.

View in: PubMed Mentions: 18 Fields:
Neo Neoplasms Neu Neurology
Translation:Humans
HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads. J Virol. 2016 10 15; 90(20):8968-83. Lamers SL, Rose R, Maidji E, Agsalda-Garcia M, Nolan DJ, Fogel GB, Salemi M, Garcia DL, Bracci P, Yong W, Commins D, Said J, Khanlou N, Hinkin CH, Sueiras MV, Mathisen G, Donovan S, Shiramizu B, Stoddart CA, McGrath MS, Singer EJ. PMID: 27466426; PMCID: PMC5044815.

View in: PubMed Mentions: 94 Fields:
Vir Virology
Translation:Humans
Mutations in TFAM, encoding mitochondrial transcription factor A, cause neonatal liver failure associated with mtDNA depletion. Mol Genet Metab. 2016 09; 119(1-2):91-9. Stiles AR, Simon MT, Stover A, Eftekharian S, Khanlou N, Wang HL, Magaki S, Lee H, Partynski K, Dorrani N, Chang R, Martinez-Agosto JA, Abdenur JE. PMID: 27448789.

View in: PubMed Mentions: 52 Fields:
Bio Biochemistry Met Metabolism Mol Molecular Biology
Translation:Humans Animals Cells PHPublic Health
Brain biopsy in atypical dementia and primary angiitis of the central nervous system--reply. Hum Pathol. 2016 May; 51:147-8. Magaki S, Gardner T, Khanlou N, Yong WH, Salamon N, Vinters HV. PMID: 26980043.

View in: PubMed Mentions: 1 Fields:
Pat Pathology
Translation:Humans
Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction. Cancer Cell. 2015 Feb 09; 27(2):240-56. Moriceau G, Hugo W, Hong A, Shi H, Kong X, Yu CC, Koya RC, Samatar AA, Khanlou N, Braun J, Ruchalski K, Seifert H, Larkin J, Dahlman KB, Johnson DB, Algazi A, Sosman JA, Ribas A, Lo RS. PMID: 25600339; PMCID: PMC4326539.

View in: PubMed Mentions: 173 Fields:
Neo Neoplasms
Translation:Humans Cells
Brain biopsy in neurologic decline of unknown etiology. Hum Pathol. 2015 Apr; 46(4):499-506. Magaki S, Gardner T, Khanlou N, Yong WH, Salamon N, Vinters HV. PMID: 25661242; PMCID: PMC4380782.

View in: PubMed Mentions: 10 Fields:
Pat Pathology
Translation:Humans
Neuropathology and genetics of cerebroretinal vasculopathies. Brain Pathol. 2014 Sep; 24(5):510-8. Kolar GR, Kothari PH, Khanlou N, Jen JC, Schmidt RE, Vinters HV. PMID: 25323666; PMCID: PMC8029267.

View in: PubMed Mentions: 20 Fields:
Bra Brain Pat Pathology
Translation:Humans
Comorbidity in dementia: update of an ongoing autopsy study. J Am Geriatr Soc. 2014 Sep; 62(9):1722-8. Magaki S, Yong WH, Khanlou N, Tung S, Vinters HV. PMID: 25039832; PMCID: PMC4172655.

View in: PubMed Mentions: 32 Fields:
Ger Geriatrics
Translation:Humans
Lyophilized brain tumor specimens can be used for histologic, nucleic acid, and protein analyses after 1 year of room temperature storage. J Neurooncol. 2013 Jul; 113(3):365-73. Mareninov S, De Jesus J, Sanchez DE, Kay AB, Wilson RW, Babic I, Chen W, Telesca D, Lou JJ, Mirsadraei L, Gardner TP, Khanlou N, Vinters HV, Shafa BB, Lai A, Liau LM, Mischel PS, Cloughesy TF, Yong WH. PMID: 23640138; PMCID: PMC3886564.

View in: PubMed Mentions: 12 Fields:
Neo Neoplasms Neu Neurology
Translation:Humans Cells
Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome. Neuro Oncol. 2013 Mar; 15(3):370-81. Lalezari S, Chou AP, Tran A, Solis OE, Khanlou N, Chen W, Li S, Carrillo JA, Chowdhury R, Selfridge J, Sanchez DE, Wilson RW, Zurayk M, Lalezari J, Lou JJ, Ormiston L, Ancheta K, Hanna R, Miller P, Piccioni D, Ellingson BM, Buchanan C, Mischel PS, Nghiemphu PL, Green R, Wang HJ, Pope WB, Liau LM, Elashoff RM, Cloughesy TF, Yong WH, Lai A. PMID: 23328811; PMCID: PMC3578486.

View in: PubMed Mentions: 61 Fields:
Neo Neoplasms Neu Neurology
Translation:Humans Cells
The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology. PLoS One. 2012; 7(9):e46308. Nalbandian A, Llewellyn KJ, Kitazawa M, Yin HZ, Badadani M, Khanlou N, Edwards R, Nguyen C, Mukherjee J, Mozaffar T, Watts G, Weiss J, Kimonis VE. PMID: 23029473; PMCID: PMC3460820.

View in: PubMed Mentions: 38 Fields:
Med Medicine (General)Sci Science
Translation:Humans Animals Cells
Cortical dysplasia with prominent Rosenthal fiber formation in a case of intractable pediatric epilepsy. Hum Pathol. 2009 Aug; 40(8):1200-4. Khanlou N, Mathern GW, Mitchell WG, Salamon N, Pope WB, Yong WH, Vinters HV. PMID: 19427021.

View in: PubMed Mentions: 4 Fields:
Pat Pathology
Translation:Humans Cells
Increased frequency of alpha-synuclein in the substantia nigra in human immunodeficiency virus infection. J Neurovirol. 2009 Apr; 15(2):131-8. Khanlou N, Moore DJ, Chana G, Cherner M, Lazzaretto D, Dawes S, Grant I, Masliah E, Everall IP, HNRC Group. PMID: 19115126; PMCID: PMC3979854.

View in: PubMed Mentions: 48 Fields:
Neu Neurology Vir Virology
Translation:Humans Cells
Hemangiopericytoma of the cerebellopontine angle: a case report and review of the literature. Surg Neurol. 2009 Sep; 72(3):290-5. Tashjian VS, Khanlou N, Vinters HV, Canalis RF, Becker DP. PMID: 18786704.

View in: PubMed Mentions: 7 Fields:
Neu Neurosurgery
Translation:Humans
Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors. Proc Natl Acad Sci U S A. 2007 Jun 19; 104(25):10601-6. Zelcer N, Khanlou N, Clare R, Jiang Q, Reed-Geaghan EG, Landreth GE, Vinters HV, Tontonoz P. PMID: 17563384; PMCID: PMC1890560.

View in: PubMed Mentions: 157 Fields:
Sci Science
Translation:Animals Cells
Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia. Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15533-8. Glatt SJ, Everall IP, Kremen WS, Corbeil J, Sásik R, Khanlou N, Han M, Liew CC, Tsuang MT. PMID: 16223876; PMCID: PMC1266138.

View in: PubMed Mentions: 144 Fields:
Sci Science
Translation:Humans Cells