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Symptomatic vigabatrin-associated MRI toxicity is associated with simultaneous hormonal therapy among patients with infantile spasms. Epilepsia Open. 2024 Nov 21.
Sathe R, Shrestha G, Terango A, Tabibzadeh D, Rajaraman RR, Nariai H, Hussain SA. PMID: 39570186.
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Multi-disciplinary team approach for pediatric hemimegalencephaly: Insights from a single institutional case series. Epilepsia Open. 2024 Oct 23.
Edmonds B, Ngo JP, Groves A, Reyes B, Gott RA, Chia DJ, Mirbaha H, Magaki S, Khanlou N, Pineles SL, Salamon N, Thompson RM, Newman M, Rajaraman RR, Hussain SA, Fallah A, Russell B, Nariai H. PMID: 39442533.
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Deletions in the CDKL5 5' untranslated region lead to CDKL5 deficiency disorder. Am J Med Genet A. 2024 Aug 28; e63843.
Haviland I, Hector RD, Swanson LC, Verran AS, Sherrill E, Frazier Z, Denny AM, Lucash J, Zhang B, Dubbs HA, Marsh ED, Weisenberg JL, Leonard H, Crippa M, Cogliati F, Russo S, Suter B, Rajaraman R, Percy AK, Schreiber JM, Demarest S, Benke TA, Chopra M, Yu TW, Olson HE. PMID: 39205479.
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Psychometric evaluation of clinician- and caregiver-reported clinical severity assessments for individuals with CDKL5 deficiency disorder. Epilepsia. 2024 Oct; 65(10):3064-3075.
Saldaris JM, Jacoby P, Downs J, Marsh ED, Leonard H, Pestana-Knight E, Rajaraman R, Weisenberg J, Suter B, Olson HE, Price D, Hong W, Prange E, Benke TA, Demarest S. PMID: 39190322; PMCID: PMC11495992.
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Humans
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Overnight Electroencephalogram to Forecast Epilepsy Development in Children with Autism Spectrum Disorders. J Pediatr. 2024 Nov; 274:114217.
Daida A, Oana S, Nadkarni D, Espiritu BL, Edmonds BD, Stanecki C, Samuel AS, Rao LM, Rajaraman RR, Hussain SA, Matsumoto JH, Sankar R, Hannauer PS, Nariai H. PMID: 39074735.
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Humans
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Caregiver Perspective of Benefits and Side Effects of Anti-Seizure Medications in CDKL5 Deficiency Disorder from an International Database. CNS Drugs. 2024 Sep; 38(9):719-732.
Wong K, Junaid M, Alexander S, Olson HE, Pestana-Knight EM, Rajaraman RR, Downs J, Leonard H. PMID: 39060900; PMCID: PMC11316688.
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1 Fields:
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Humans
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Modification of a parent-report sleep scale for individuals with CDKL5 deficiency disorder: a psychometric study. J Clin Sleep Med. 2024 Jul 04.
Saldaris JM, Demarest S, Jacoby P, Olson HE, Maski K, Pestana-Knight E, Price D, Rajaraman R, Suter B, Weisenberg J, Leonard H, Marsh ED, Benke TA, Downs J. PMID: 38963064.
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1 Fields:
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Humans
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Drug-Resistant Epilepsy in Tuberous Sclerosis Complex Is Associated With TSC2 Genotype: More Findings From the Preventing Epilepsy Using Vigatrin (PREVeNT) Trial. Pediatr Neurol. 2024 Oct; 159:62-71.
Farach LS, Richard MA, Wulsin AC, Bebin EM, Krueger DA, Sahin M, Porter BE, McPherson TO, Peters JM, O'Kelley S, Taub KS, Rajaraman R, Randle SC, McClintock WM, Koenig MK, Frost MD, Werner K, Nolan DA, Wong M, Cutter G, Northrup H, Au KS, PREVeNT Study Group. PMID: 39142021.
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1 Fields:
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Humans
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Effects of ganaxolone on non-seizure outcomes in CDKL5 Deficiency Disorder: Double-blind placebo-controlled randomized trial. Eur J Paediatr Neurol. 2024 Jul; 51:140-146.
Downs J, Jacoby P, Specchio N, Cross H, Amin S, Bahi-Buisson N, Rajaraman R, Suter B, Devinsky O, Aimetti A, Busse G, Olson HE, Demarest S, Benke TA, Pestana-Knight E. PMID: 38959712; PMCID: PMC11283350.
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2 Fields:
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Humans
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Humans
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Computational EEG attributes predict response to therapy for epileptic spasms. Clin Neurophysiol. 2024 Jul; 163:39-46.
Rajaraman RR, Smith RJ, Oana S, Daida A, Shrey DW, Nariai H, Lopour BA, Hussain SA. PMID: 38703698.
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Humans
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Epileptic spasms relapse is associated with response latency but not conventional attributes of post-treatment EEG. Epilepsia Open. 2024 Jun; 9(3):1034-1041.
Deckard E, Sathe R, Tabibzadeh D, Terango A, Groves A, Rajaraman RR, Nariai H, Hussain SA. PMID: 38588009; PMCID: PMC11145600.
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1 Fields:
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Humans
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Adapting a measure of gross motor skills for individuals with CDKL5 deficiency disorder: A psychometric study. Epilepsy Res. 2024 Feb; 200:107287.
Saldaris JM, Jacoby P, Marsh ED, Suter B, Leonard H, Olson HE, Rajaraman R, Pestana-Knight E, Weisenberg J, Price D, Drummond C, Benke TA, Demarest S, Downs J. PMID: 38237219.
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1 Fields:
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Humans
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Long-term treatment with ganaxolone for seizures associated with cyclin-dependent kinase-like 5 deficiency disorder: Two-year open-label extension follow-up. Epilepsia. 2024 Jan; 65(1):37-45.
Olson HE, Amin S, Bahi-Buisson N, Devinsky O, Marsh ED, Pestana-Knight E, Rajaraman RR, Aimetti AA, Rybak E, Kong F, Miller I, Hulihan J, Demarest S. PMID: 37950390.
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8 Fields:
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Humans
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The development, content and response process validation of a caregiver-reported severity measure for CDKL5 deficiency disorder. Epilepsy Res. 2023 11; 197:107231.
Ziniel SI, Mackie A, Saldaris J, Leonard H, Jacoby P, Marsh ED, Suter B, Pestana-Knight E, Olson HE, Price D, Weisenberg J, Rajaraman R, VanderVeen G, Benke TA, Downs J, Demarest S. PMID: 37751639; PMCID: PMC10760432.
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1 Fields:
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Humans
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Early Treatment with Vigabatrin Does Not Decrease Focal Seizures or Improve Cognition in Tuberous Sclerosis Complex: The PREVeNT Trial. Ann Neurol. 2023 Aug 28.
Bebin EM, Peters JM, Porter BE, McPherson TO, O'Kelley S, Sahin M, Taub KS, Rajaraman R, Randle SC, McClintock WM, Koenig MK, Frost MD, Northrup HA, Werner K, Nolan DA, Wong M, Krefting JL, Biasini F, Peri K, Cutter G, Krueger DA, PREVeNT Study Group. PMID: 37638552; PMCID: PMC10899525.
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9 Fields:
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Epileptic spasms in CDKL5 deficiency disorder: Delayed treatment and poor response to first-line therapies. Epilepsia. 2023 07; 64(7):1821-1832.
Olson HE, Demarest S, Pestana-Knight E, Moosa AN, Zhang X, Pérez-Pérez JR, Weisenberg J, O'Connor Prange E, Marsh ED, Rajaraman RR, Suter B, Katyayan A, Haviland I, Daniels C, Zhang B, Greene C, DeLeo M, Swanson L, Love-Nichols J, Benke T, Harini C, Poduri A. PMID: 37114835; PMCID: PMC10524264.
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3 Fields:
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Humans
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Automated preprocessing and phase-amplitude coupling analysis of scalp EEG discriminates infantile spasms from controls during wakefulness. Epilepsy Res. 2021 12; 178:106809.
Miyakoshi M, Nariai H, Rajaraman RR, Bernardo D, Shrey DW, Lopour BA, Sim MS, Staba RJ, Hussain SA. PMID: 34823159.
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3 Fields:
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Humans
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Content Validation of Clinician-Reported Items for a Severity Measure for CDKL5 Deficiency Disorder. J Child Neurol. 2021 10; 36(11):998-1006.
Saldaris J, Weisenberg J, Pestana-Knight E, Marsh ED, Suter B, Rajaraman R, Heidary G, Olson HE, Devinsky O, Price D, Jacoby P, Leonard H, Benke TA, Demarest S, Downs J. PMID: 34378447; PMCID: PMC8458223.
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11 Fields:
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Humans
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Computational characteristics of interictal EEG as objective markers of epileptic spasms. Epilepsy Res. 2021 10; 176:106704.
Smith RJ, Hu DK, Shrey DW, Rajaraman R, Hussain SA, Lopour BA. PMID: 34218209.
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9 Fields:
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Humans
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Potential induction of epileptic spasms by nonselective voltage-gated sodium channel blockade: Interaction with etiology. Epilepsy Behav. 2021 02; 115:107624.
Hussain SA, Heesch J, Weng J, Rajaraman RR, Numis AL, Sankar R. PMID: 33341392.
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4 Fields:
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Humans
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Felbamate in the treatment of refractory epileptic spasms. Epilepsy Res. 2020 03; 161:106284.
Hussain SA, Asilnejad B, Heesch J, Navarro M, Ji M, Shrey DW, Rajaraman RR, Sankar R. PMID: 32058261.
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3 Fields:
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Humans
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Limited efficacy of zonisamide in the treatment of refractory infantile spasms. Epilepsia Open. 2020 Mar; 5(1):121-126.
Hussain SA, Navarro M, Heesch J, Ji M, Asilnejad B, Peters H, Rajaraman RR, Sankar R. PMID: 32140650; PMCID: PMC7049796.
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3 Fields:
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Prospective observational study: Fast ripple localization delineates the epileptogenic zone. Clin Neurophysiol. 2019 11; 130(11):2144-2152.
Nariai H, Hussain SA, Bernardo D, Fallah A, Murata KK, Nguyen JC, Rajaraman RR, Rao LM, Matsumoto JH, Lerner JT, Salamon N, Elashoff D, Sankar R, Wu JY. PMID: 31569042.
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17 Fields:
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Humans
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Very-High-Dose Prednisolone Before ACTH for Treatment of Infantile Spasms: Evaluation of a Standardized Protocol. Pediatr Neurol. 2019 10; 99:16-22.
Eliyan Y, Heesch J, Alayari A, Rajaraman RR, Sankar R, Hussain SA. PMID: 31331669.
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8 Fields:
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Humans
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Strength and stability of EEG functional connectivity predict treatment response in infants with epileptic spasms. Clin Neurophysiol. 2018 10; 129(10):2137-2148.
Shrey DW, Kim McManus O, Rajaraman R, Ombao H, Hussain SA, Lopour BA. PMID: 30114662; PMCID: PMC6193760.
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20 Fields:
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Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus. Epilepsy Behav Case Rep. 2018; 10:141-144.
Rajaraman RR, Sankar R, Hussain SA. PMID: 30596011; PMCID: PMC6306515.
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2
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AR2, a novel automatic muscle artifact reduction software method for ictal EEG interpretation: Validation and comparison of performance with commercially available software. F1000Res. 2017; 6:30.
Weiss SA, Asadi-Pooya AA, Vangala S, Moy S, Wyeth DH, Orosz I, Gibbs M, Schrader L, Lerner J, Cheng CK, Chang E, Rajaraman R, Keselman I, Churchman P, Bower-Baca C, Numis AL, Ho MG, Rao L, Bhat A, Suski J, Asadollahi M, Ambrose T, Fernandez A, Nei M, Skidmore C, Mintzer S, Eliashiv DS, Mathern GW, Nuwer MR, Sperling M, Engel J, Stern JM. PMID: 28491280; PMCID: PMC5399961.
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3 Fields:
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Prevention of infantile spasms relapse: Zonisamide and topiramate provide no benefit. Epilepsia. 2016 08; 57(8):1280-7.
Rajaraman RR, Lay J, Alayari A, Anderson K, Sankar R, Hussain SA. PMID: 27312124.
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6 Fields:
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Humans
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Correlation of health-related quality of life in children with inflammatory bowel disease, their parents, and physician as measured by a visual analog scale. J Pediatr Gastroenterol Nutr. 2013 Nov; 57(5):594-7.
Teitelbaum JE, Rajaraman RR, Jaeger J, Para S, Rakitt T. PMID: 23752079.
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2 Fields:
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Humans
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Inaccuracy of stated versus measured parental heights. Clin Pediatr (Phila). 2005 May; 44(4):339-41.
Teitelbaum JE, Koreen S, Hightower K, Rajaraman R, Jaeger J. PMID: 15864367.
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2 Fields:
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Humans