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Tobin, Nicole H

Title(s)Associate Adjunct Professor, Pediatrics
SchoolPed - Infectious Diseases
Phone57708
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    Collapse Research 
    Collapse Research Activities and Funding
    Persistent Replication of HIV-1 in Children
    NIH/NIAID K23AI058683Mar 1, 2004 - Jul 15, 2005
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Farr Zuend C, Tobin NH, Vera T, Kotyrba L, Noël-Romas L, Birse K, Mutch S, Li F, Lee D, McCorrister S, Westmacott G, Aldrovandi GM, Burgener A. Pregnancy associates with alterations to the host and microbial proteome in vaginal mucosa. Am J Reprod Immunol. 2020 Mar 20; e13235. PMID: 32196803.
      View in: PubMed
    2. Kordy K, Gaufin T, Mwangi M, Li F, Cerini C, Lee DJ, Adisetiyo H, Woodward C, Pannaraj PS, Tobin NH, Aldrovandi GM. Contributions to human breast milk microbiome and enteromammary transfer of Bifidobacterium breve. PLoS One. 2020; 15(1):e0219633. PMID: 31990909.
      View in: PubMed
    3. Cook RR, Fulcher JA, Tobin NH, Li F, Lee D, Woodward C, Javanbakht M, Brookmeyer R, Shoptaw S, Bolan R, Aldrovandi GM, Gorbach PM. Combined effects of HIV and obesity on the gastrointestinal microbiome of young men who have sex with men. HIV Med. 2019 Dec 27. PMID: 31883184.
      View in: PubMed
    4. Cook RR, Fulcher JA, Tobin NH, Li F, Lee DJ, Woodward C, Javanbakht M, Brookmeyer R, Shoptaw S, Bolan R, Aldrovandi GM, Gorbach PM. Alterations to the Gastrointestinal Microbiome Associated with Methamphetamine Use among Young Men who have Sex with Men. Sci Rep. 2019 Oct 16; 9(1):14840. PMID: 31619731.
      View in: PubMed
    5. Cook RR, Fulcher JA, Tobin NH, Li F, Lee D, Javanbakht M, Brookmeyer R, Shoptaw S, Bolan R, Aldrovandi GM, Gorbach PM. Effects of HIV viremia on the gastrointestinal microbiome of young MSM. AIDS. 2019 04 01; 33(5):793-804. PMID: 30649052.
      View in: PubMed
    6. Fulcher JA, Hussain SK, Cook R, Li F, Tobin NH, Ragsdale A, Shoptaw S, Gorbach PM, Aldrovandi GM. Effects of Substance Use and Sex Practices on the Intestinal Microbiome During HIV-1 Infection. J Infect Dis. 2018 10 05; 218(10):1560-1570. PMID: 29982500.
      View in: PubMed
    7. Bender JM, Li F, Adisetiyo H, Lee D, Zabih S, Hung L, Wilkinson TA, Pannaraj PS, She RC, Bard JD, Tobin NH, Aldrovandi GM. Quantification of variation and the impact of biomass in targeted 16S rRNA gene sequencing studies. Microbiome. 2018 09 10; 6(1):155. PMID: 30201048.
      View in: PubMed
    8. Kordy K, Romeo AC, Lee DJ, Li F, Zabih S, Saavedra M, Cunningham NJ, Tobin N, Aldrovandi GM. Combination Antibiotics Improves Disease Activity and Alters Microbial Communities in Children With Ulcerative Colitis. J Pediatr Gastroenterol Nutr. 2018 09; 67(3):e60-e63. PMID: 29762192.
      View in: PubMed
    9. Tobin NH, Woodward C, Zabih S, Lee DJ, Li F, Aldrovandi GM. A Method for Targeted 16S Sequencing of Human Milk Samples. J Vis Exp. 2018 03 23; (133). PMID: 29630048.
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    10. Gaufin T, Tobin NH, Aldrovandi GM. The importance of the microbiome in pediatrics and pediatric infectious diseases. Curr Opin Pediatr. 2018 02; 30(1):117-124. PMID: 29206649.
      View in: PubMed
    11. Nakamura KJ, Heath L, Sobrera ER, Wilkinson TA, Semrau K, Kankasa C, Tobin NH, Webb NE, Lee B, Thea DM, Kuhn L, Mullins JI, Aldrovandi GM. Breast milk and in utero transmission of HIV-1 select for envelope variants with unique molecular signatures. Retrovirology. 2017 01 26; 14(1):6. PMID: 28122636.
      View in: PubMed
    12. Ruan A, Tobin NH, Mulligan K, Rollie A, Li F, Sleasman J, Aldrovandi GM. Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021. J Acquir Immune Defic Syndr. 2016 08 01; 72(4):372-5. PMID: 26885808.
      View in: PubMed
    13. Bender JM, Li F, Martelly S, Byrt E, Rouzier V, Leo M, Tobin N, Pannaraj PS, Adisetiyo H, Rollie A, Santiskulvong C, Wang S, Autran C, Bode L, Fitzgerald D, Kuhn L, Aldrovandi GM. Maternal HIV infection influences the microbiome of HIV-uninfected infants. Sci Transl Med. 2016 07 27; 8(349):349ra100. PMID: 27464748.
      View in: PubMed
    14. Lombardi F, Nakamura KJ, Chen T, Sobrera ER, Tobin NH, Aldrovandi GM. A Conserved Glycan in the C2 Domain of HIV-1 Envelope Acts as a Molecular Switch to Control X4 Utilization by Clonal Variants with Identical V3 Loops. PLoS One. 2015; 10(6):e0128116. PMID: 26083631.
      View in: PubMed
    15. Tobin NH, Aldrovandi GM. Are infants unique in their ability to be "functionally cured" of HIV-1? Curr HIV/AIDS Rep. 2014 Mar; 11(1):1-10. PMID: 24390641.
      View in: PubMed
    16. Tobin NH, Aldrovandi GM. Immunology of pediatric HIV infection. Immunol Rev. 2013 Jul; 254(1):143-69. PMID: 23772619.
      View in: PubMed
    17. Wagner TA, McKernan JL, Tobin NH, Tapia KA, Mullins JI, Frenkel LM. An increasing proportion of monotypic HIV-1 DNA sequences during antiretroviral treatment suggests proliferation of HIV-infected cells. J Virol. 2013 Feb; 87(3):1770-8. PMID: 23175380.
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    18. Wagner TA, Lin CH, Tobin NH, Côté HC, Sloan DD, Jerome KR, Frenkel LM. Quantification of mitochondrial toxicity in HIV-infected individuals by quantitative PCR compared to flow cytometry. Cytometry B Clin Cytom. 2013 Jan-Feb; 84(1):55-8. PMID: 23044657.
      View in: PubMed
    19. Wagner TA, Tobin NH, McKernan JL, Xu M, Melvin AJ, Mohan KM, Learn GH, Mullins JI, Frenkel LM. Increased mutations in Env and Pol suggest greater HIV-1 replication in sputum-derived viruses compared with blood-derived viruses. AIDS. 2009 May 15; 23(8):923-8. PMID: 19349849.
      View in: PubMed
    20. Lin CH, Sloan DD, Dang CH, Wagner T, Cabrera AJ, Tobin NH, Frenkel LM, Jerome KR. Assessment of mitochondrial toxicity by analysis of mitochondrial protein expression in mononuclear cells. Cytometry B Clin Cytom. 2009 May; 76(3):181-90. PMID: 18823003.
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    21. Holte SE, Melvin AJ, Mullins JI, Tobin NH, Frenkel LM. Density-dependent decay in HIV-1 dynamics. J Acquir Immune Defic Syndr. 2006 Mar; 41(3):266-76. PMID: 16540927.
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    22. Tobin NH, Learn GH, Holte SE, Wang Y, Melvin AJ, McKernan JL, Pawluk DM, Mohan KM, Lewis PF, Mullins JI, Frenkel LM. Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: expression of archival virus and replication of virus. J Virol. 2005 Aug; 79(15):9625-34. PMID: 16014925.
      View in: PubMed
    23. Frenkel LM, Tobin NH. Understanding HIV-1 drug resistance. Ther Drug Monit. 2004 Apr; 26(2):116-21. PMID: 15228150.
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    24. Frenkel LM, Wang Y, Learn GH, McKernan JL, Ellis GM, Mohan KM, Holte SE, De Vange SM, Pawluk DM, Melvin AJ, Lewis PF, Heath LM, Beck IA, Mahalanabis M, Naugler WE, Tobin NH, Mullins JI. Multiple viral genetic analyses detect low-level human immunodeficiency virus type 1 replication during effective highly active antiretroviral therapy. J Virol. 2003 May; 77(10):5721-30. PMID: 12719565.
      View in: PubMed
    25. Tobin NH, Frenkel LM. Human immunodeficiency virus drug susceptibility and resistance testing. Pediatr Infect Dis J. 2002 Jul; 21(7):681-3. PMID: 12237603.
      View in: PubMed